Amino acid dipepetide frequency for CRESS virus sp. ctYls24

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.522AlaAla: 1.522 ± 1.159
0.0AlaCys: 0.0 ± 0.0
1.522AlaAsp: 1.522 ± 1.159
4.566AlaGlu: 4.566 ± 2.733
3.044AlaPhe: 3.044 ± 2.15
7.61AlaGly: 7.61 ± 2.441
1.522AlaHis: 1.522 ± 1.067
6.088AlaIle: 6.088 ± 2.807
7.61AlaLys: 7.61 ± 2.597
6.088AlaLeu: 6.088 ± 7.283
0.0AlaMet: 0.0 ± 0.0
3.044AlaAsn: 3.044 ± 2.317
0.0AlaPro: 0.0 ± 0.0
0.0AlaGln: 0.0 ± 0.0
1.522AlaArg: 1.522 ± 1.067
1.522AlaSer: 1.522 ± 1.159
3.044AlaThr: 3.044 ± 0.837
1.522AlaVal: 1.522 ± 2.547
1.522AlaTrp: 1.522 ± 1.067
7.61AlaTyr: 7.61 ± 3.936
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.522CysGlu: 1.522 ± 1.067
3.044CysPhe: 3.044 ± 2.134
1.522CysGly: 1.522 ± 1.067
0.0CysHis: 0.0 ± 0.0
1.522CysIle: 1.522 ± 1.067
1.522CysLys: 1.522 ± 1.067
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.522CysSer: 1.522 ± 2.547
0.0CysThr: 0.0 ± 0.0
1.522CysVal: 1.522 ± 1.067
0.0CysTrp: 0.0 ± 0.0
1.522CysTyr: 1.522 ± 1.067
0.0CysXaa: 0.0 ± 0.0
Asp
1.522AspAla: 1.522 ± 1.067
0.0AspCys: 0.0 ± 0.0
4.566AspAsp: 4.566 ± 3.201
3.044AspGlu: 3.044 ± 2.232
0.0AspPhe: 0.0 ± 0.0
3.044AspGly: 3.044 ± 2.134
1.522AspHis: 1.522 ± 1.159
1.522AspIle: 1.522 ± 1.067
6.088AspLys: 6.088 ± 4.269
6.088AspLeu: 6.088 ± 3.867
0.0AspMet: 0.0 ± 0.0
4.566AspAsn: 4.566 ± 1.529
1.522AspPro: 1.522 ± 2.185
1.522AspGln: 1.522 ± 1.159
0.0AspArg: 0.0 ± 0.0
6.088AspSer: 6.088 ± 1.675
0.0AspThr: 0.0 ± 0.0
0.0AspVal: 0.0 ± 0.0
1.522AspTrp: 1.522 ± 1.067
3.044AspTyr: 3.044 ± 2.317
0.0AspXaa: 0.0 ± 0.0
Glu
6.088GluAla: 6.088 ± 3.498
6.088GluCys: 6.088 ± 4.269
3.044GluAsp: 3.044 ± 4.369
10.654GluGlu: 10.654 ± 10.704
1.522GluPhe: 1.522 ± 1.159
4.566GluGly: 4.566 ± 2.733
3.044GluHis: 3.044 ± 2.134
1.522GluIle: 1.522 ± 1.067
3.044GluLys: 3.044 ± 2.134
3.044GluLeu: 3.044 ± 4.369
1.522GluMet: 1.522 ± 1.067
1.522GluAsn: 1.522 ± 1.067
1.522GluPro: 1.522 ± 1.067
4.566GluGln: 4.566 ± 1.529
3.044GluArg: 3.044 ± 2.232
3.044GluSer: 3.044 ± 2.15
4.566GluThr: 4.566 ± 3.201
3.044GluVal: 3.044 ± 2.232
3.044GluTrp: 3.044 ± 2.232
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
1.522PheGlu: 1.522 ± 1.067
9.132PhePhe: 9.132 ± 12.546
3.044PheGly: 3.044 ± 0.837
0.0PheHis: 0.0 ± 0.0
3.044PheIle: 3.044 ± 2.339
6.088PheLys: 6.088 ± 3.205
4.566PheLeu: 4.566 ± 7.64
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
1.522PheGln: 1.522 ± 2.185
3.044PheArg: 3.044 ± 0.837
6.088PheSer: 6.088 ± 3.519
1.522PheThr: 1.522 ± 1.159
4.566PheVal: 4.566 ± 1.953
1.522PheTrp: 1.522 ± 1.159
3.044PheTyr: 3.044 ± 3.497
0.0PheXaa: 0.0 ± 0.0
Gly
3.044GlyAla: 3.044 ± 2.134
1.522GlyCys: 1.522 ± 1.067
1.522GlyAsp: 1.522 ± 1.067
6.088GlyGlu: 6.088 ± 4.269
9.132GlyPhe: 9.132 ± 3.868
3.044GlyGly: 3.044 ± 0.837
1.522GlyHis: 1.522 ± 1.067
3.044GlyIle: 3.044 ± 2.317
4.566GlyLys: 4.566 ± 1.717
1.522GlyLeu: 1.522 ± 1.067
1.522GlyMet: 1.522 ± 2.185
4.566GlyAsn: 4.566 ± 1.529
3.044GlyPro: 3.044 ± 2.317
1.522GlyGln: 1.522 ± 2.185
6.088GlyArg: 6.088 ± 2.202
10.654GlySer: 10.654 ± 4.507
1.522GlyThr: 1.522 ± 1.159
3.044GlyVal: 3.044 ± 0.837
0.0GlyTrp: 0.0 ± 0.0
4.566GlyTyr: 4.566 ± 1.529
0.0GlyXaa: 0.0 ± 0.0
His
1.522HisAla: 1.522 ± 1.067
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.522HisGlu: 1.522 ± 1.067
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
4.566HisIle: 4.566 ± 2.594
0.0HisLys: 0.0 ± 0.0
3.044HisLeu: 3.044 ± 2.134
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.522HisPro: 1.522 ± 1.067
3.044HisGln: 3.044 ± 2.571
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
3.044HisTrp: 3.044 ± 2.134
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.566IleAla: 4.566 ± 1.717
1.522IleCys: 1.522 ± 2.547
6.088IleAsp: 6.088 ± 2.501
3.044IleGlu: 3.044 ± 2.232
1.522IlePhe: 1.522 ± 2.547
7.61IleGly: 7.61 ± 2.693
0.0IleHis: 0.0 ± 0.0
3.044IleIle: 3.044 ± 0.837
4.566IleLys: 4.566 ± 1.529
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
1.522IleAsn: 1.522 ± 2.185
0.0IlePro: 0.0 ± 0.0
3.044IleGln: 3.044 ± 0.837
3.044IleArg: 3.044 ± 2.339
3.044IleSer: 3.044 ± 0.837
0.0IleThr: 0.0 ± 0.0
6.088IleVal: 6.088 ± 1.675
1.522IleTrp: 1.522 ± 1.067
4.566IleTyr: 4.566 ± 3.07
0.0IleXaa: 0.0 ± 0.0
Lys
1.522LysAla: 1.522 ± 1.067
0.0LysCys: 0.0 ± 0.0
4.566LysAsp: 4.566 ± 1.529
9.132LysGlu: 9.132 ± 5.466
1.522LysPhe: 1.522 ± 1.159
10.654LysGly: 10.654 ± 5.627
1.522LysHis: 1.522 ± 1.067
4.566LysIle: 4.566 ± 3.201
6.088LysLys: 6.088 ± 2.501
1.522LysLeu: 1.522 ± 1.067
3.044LysMet: 3.044 ± 2.55
1.522LysAsn: 1.522 ± 1.067
1.522LysPro: 1.522 ± 1.067
6.088LysGln: 6.088 ± 4.461
4.566LysArg: 4.566 ± 1.717
3.044LysSer: 3.044 ± 0.837
7.61LysThr: 7.61 ± 5.336
0.0LysVal: 0.0 ± 0.0
4.566LysTrp: 4.566 ± 3.201
1.522LysTyr: 1.522 ± 1.159
0.0LysXaa: 0.0 ± 0.0
Leu
4.566LeuAla: 4.566 ± 3.296
0.0LeuCys: 0.0 ± 0.0
4.566LeuAsp: 4.566 ± 3.201
10.654LeuGlu: 10.654 ± 6.03
6.088LeuPhe: 6.088 ± 5.344
3.044LeuGly: 3.044 ± 5.094
1.522LeuHis: 1.522 ± 2.547
3.044LeuIle: 3.044 ± 3.497
3.044LeuLys: 3.044 ± 2.134
6.088LeuLeu: 6.088 ± 2.672
0.0LeuMet: 0.0 ± 0.0
3.044LeuAsn: 3.044 ± 2.571
1.522LeuPro: 1.522 ± 1.067
3.044LeuGln: 3.044 ± 2.317
4.566LeuArg: 4.566 ± 1.717
4.566LeuSer: 4.566 ± 1.747
4.566LeuThr: 4.566 ± 2.676
1.522LeuVal: 1.522 ± 2.547
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.044MetAla: 3.044 ± 2.15
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.044MetGlu: 3.044 ± 0.837
0.0MetPhe: 0.0 ± 0.0
1.522MetGly: 1.522 ± 1.159
0.0MetHis: 0.0 ± 0.0
1.522MetIle: 1.522 ± 1.067
3.044MetLys: 3.044 ± 2.134
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.522MetAsn: 1.522 ± 2.185
0.0MetPro: 0.0 ± 0.0
1.522MetGln: 1.522 ± 2.547
1.522MetArg: 1.522 ± 1.159
1.522MetSer: 1.522 ± 1.159
1.522MetThr: 1.522 ± 1.067
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.522AsnAla: 1.522 ± 1.159
0.0AsnCys: 0.0 ± 0.0
3.044AsnAsp: 3.044 ± 2.317
3.044AsnGlu: 3.044 ± 2.232
1.522AsnPhe: 1.522 ± 2.185
1.522AsnGly: 1.522 ± 1.159
0.0AsnHis: 0.0 ± 0.0
3.044AsnIle: 3.044 ± 2.339
1.522AsnLys: 1.522 ± 1.067
1.522AsnLeu: 1.522 ± 2.547
1.522AsnMet: 1.522 ± 1.067
0.0AsnAsn: 0.0 ± 0.0
9.132AsnPro: 9.132 ± 5.079
3.044AsnGln: 3.044 ± 2.571
0.0AsnArg: 0.0 ± 0.0
4.566AsnSer: 4.566 ± 1.717
3.044AsnThr: 3.044 ± 0.837
1.522AsnVal: 1.522 ± 1.067
0.0AsnTrp: 0.0 ± 0.0
1.522AsnTyr: 1.522 ± 1.067
0.0AsnXaa: 0.0 ± 0.0
Pro
1.522ProAla: 1.522 ± 1.159
0.0ProCys: 0.0 ± 0.0
3.044ProAsp: 3.044 ± 2.134
1.522ProGlu: 1.522 ± 1.067
1.522ProPhe: 1.522 ± 1.159
3.044ProGly: 3.044 ± 2.134
0.0ProHis: 0.0 ± 0.0
1.522ProIle: 1.522 ± 1.159
4.566ProLys: 4.566 ± 2.733
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
1.522ProAsn: 1.522 ± 1.159
1.522ProPro: 1.522 ± 1.159
0.0ProGln: 0.0 ± 0.0
3.044ProArg: 3.044 ± 2.571
3.044ProSer: 3.044 ± 2.317
1.522ProThr: 1.522 ± 1.159
4.566ProVal: 4.566 ± 3.476
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.044GlnAla: 3.044 ± 2.571
1.522GlnCys: 1.522 ± 1.067
3.044GlnAsp: 3.044 ± 2.232
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
4.566GlnIle: 4.566 ± 1.717
1.522GlnLys: 1.522 ± 1.159
10.654GlnLeu: 10.654 ± 3.717
0.0GlnMet: 0.0 ± 0.0
1.522GlnAsn: 1.522 ± 2.547
1.522GlnPro: 1.522 ± 1.159
3.044GlnGln: 3.044 ± 2.571
1.522GlnArg: 1.522 ± 1.159
3.044GlnSer: 3.044 ± 2.317
0.0GlnThr: 0.0 ± 0.0
3.044GlnVal: 3.044 ± 2.339
3.044GlnTrp: 3.044 ± 2.15
3.044GlnTyr: 3.044 ± 2.339
0.0GlnXaa: 0.0 ± 0.0
Arg
4.566ArgAla: 4.566 ± 3.07
0.0ArgCys: 0.0 ± 0.0
1.522ArgAsp: 1.522 ± 1.067
1.522ArgGlu: 1.522 ± 1.067
3.044ArgPhe: 3.044 ± 2.339
3.044ArgGly: 3.044 ± 2.317
1.522ArgHis: 1.522 ± 1.067
0.0ArgIle: 0.0 ± 0.0
4.566ArgLys: 4.566 ± 1.953
7.61ArgLeu: 7.61 ± 2.693
1.522ArgMet: 1.522 ± 1.159
1.522ArgAsn: 1.522 ± 2.547
3.044ArgPro: 3.044 ± 2.339
0.0ArgGln: 0.0 ± 0.0
18.265ArgArg: 18.265 ± 7.736
4.566ArgSer: 4.566 ± 3.476
6.088ArgThr: 6.088 ± 1.675
0.0ArgVal: 0.0 ± 0.0
1.522ArgTrp: 1.522 ± 1.067
6.088ArgTyr: 6.088 ± 1.675
0.0ArgXaa: 0.0 ± 0.0
Ser
7.61SerAla: 7.61 ± 3.936
0.0SerCys: 0.0 ± 0.0
1.522SerAsp: 1.522 ± 1.159
3.044SerGlu: 3.044 ± 0.837
1.522SerPhe: 1.522 ± 2.547
9.132SerGly: 9.132 ± 5.079
3.044SerHis: 3.044 ± 2.134
6.088SerIle: 6.088 ± 3.519
4.566SerLys: 4.566 ± 1.747
0.0SerLeu: 0.0 ± 0.0
1.522SerMet: 1.522 ± 1.146
0.0SerAsn: 0.0 ± 0.0
3.044SerPro: 3.044 ± 0.837
3.044SerGln: 3.044 ± 0.837
7.61SerArg: 7.61 ± 1.597
6.088SerSer: 6.088 ± 4.461
4.566SerThr: 4.566 ± 3.476
7.61SerVal: 7.61 ± 1.655
1.522SerTrp: 1.522 ± 1.067
6.088SerTyr: 6.088 ± 2.807
0.0SerXaa: 0.0 ± 0.0
Thr
3.044ThrAla: 3.044 ± 2.134
0.0ThrCys: 0.0 ± 0.0
1.522ThrAsp: 1.522 ± 1.159
1.522ThrGlu: 1.522 ± 1.067
3.044ThrPhe: 3.044 ± 2.134
1.522ThrGly: 1.522 ± 1.159
0.0ThrHis: 0.0 ± 0.0
1.522ThrIle: 1.522 ± 1.159
1.522ThrLys: 1.522 ± 1.067
6.088ThrLeu: 6.088 ± 3.498
0.0ThrMet: 0.0 ± 0.0
9.132ThrAsn: 9.132 ± 5.079
0.0ThrPro: 0.0 ± 0.0
1.522ThrGln: 1.522 ± 1.159
0.0ThrArg: 0.0 ± 0.0
7.61ThrSer: 7.61 ± 3.528
7.61ThrThr: 7.61 ± 2.223
6.088ThrVal: 6.088 ± 4.634
0.0ThrTrp: 0.0 ± 0.0
3.044ThrTyr: 3.044 ± 0.837
0.0ThrXaa: 0.0 ± 0.0
Val
4.566ValAla: 4.566 ± 3.07
3.044ValCys: 3.044 ± 2.134
1.522ValAsp: 1.522 ± 1.067
3.044ValGlu: 3.044 ± 2.232
0.0ValPhe: 0.0 ± 0.0
3.044ValGly: 3.044 ± 2.317
0.0ValHis: 0.0 ± 0.0
3.044ValIle: 3.044 ± 2.15
3.044ValLys: 3.044 ± 0.837
4.566ValLeu: 4.566 ± 1.953
3.044ValMet: 3.044 ± 0.837
1.522ValAsn: 1.522 ± 1.067
1.522ValPro: 1.522 ± 1.159
3.044ValGln: 3.044 ± 2.317
6.088ValArg: 6.088 ± 1.816
4.566ValSer: 4.566 ± 1.953
3.044ValThr: 3.044 ± 0.837
9.132ValVal: 9.132 ± 2.512
1.522ValTrp: 1.522 ± 1.159
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
3.044TrpAsp: 3.044 ± 2.232
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.522TrpGly: 1.522 ± 1.067
0.0TrpHis: 0.0 ± 0.0
1.522TrpIle: 1.522 ± 1.067
0.0TrpLys: 0.0 ± 0.0
3.044TrpLeu: 3.044 ± 2.15
3.044TrpMet: 3.044 ± 1.933
1.522TrpAsn: 1.522 ± 1.067
0.0TrpPro: 0.0 ± 0.0
1.522TrpGln: 1.522 ± 1.159
1.522TrpArg: 1.522 ± 1.159
0.0TrpSer: 0.0 ± 0.0
1.522TrpThr: 1.522 ± 1.067
4.566TrpVal: 4.566 ± 1.529
1.522TrpTrp: 1.522 ± 1.067
3.044TrpTyr: 3.044 ± 2.134
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.088TyrAla: 6.088 ± 1.675
0.0TyrCys: 0.0 ± 0.0
1.522TyrAsp: 1.522 ± 1.159
0.0TyrGlu: 0.0 ± 0.0
3.044TyrPhe: 3.044 ± 2.339
3.044TyrGly: 3.044 ± 0.837
3.044TyrHis: 3.044 ± 2.339
0.0TyrIle: 0.0 ± 0.0
9.132TyrLys: 9.132 ± 3.058
0.0TyrLeu: 0.0 ± 0.0
1.522TyrMet: 1.522 ± 2.082
3.044TyrAsn: 3.044 ± 2.317
1.522TyrPro: 1.522 ± 1.159
3.044TyrGln: 3.044 ± 2.232
4.566TyrArg: 4.566 ± 1.717
3.044TyrSer: 3.044 ± 0.837
3.044TyrThr: 3.044 ± 2.317
1.522TyrVal: 1.522 ± 1.159
1.522TyrTrp: 1.522 ± 1.159
4.566TyrTyr: 4.566 ± 1.529
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (658 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski