Amino acid dipepetide frequency for Rattus norvegicus papillomavirus 1 (isolate Rat/Germany/Schulz/2009) (RnPV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.497AlaAla: 3.497 ± 1.644
1.748AlaCys: 1.748 ± 0.999
3.059AlaAsp: 3.059 ± 1.538
3.934AlaGlu: 3.934 ± 1.446
1.748AlaPhe: 1.748 ± 0.591
2.622AlaGly: 2.622 ± 0.974
0.437AlaHis: 0.437 ± 0.367
1.748AlaIle: 1.748 ± 0.967
3.934AlaLys: 3.934 ± 1.477
4.371AlaLeu: 4.371 ± 1.492
1.311AlaMet: 1.311 ± 0.601
1.311AlaAsn: 1.311 ± 0.369
3.934AlaPro: 3.934 ± 1.285
1.748AlaGln: 1.748 ± 0.908
3.497AlaArg: 3.497 ± 0.99
3.934AlaSer: 3.934 ± 1.715
4.371AlaThr: 4.371 ± 0.963
5.245AlaVal: 5.245 ± 1.295
0.437AlaTrp: 0.437 ± 0.346
1.311AlaTyr: 1.311 ± 0.653
0.0AlaXaa: 0.0 ± 0.0
Cys
1.311CysAla: 1.311 ± 0.695
1.311CysCys: 1.311 ± 1.039
0.874CysAsp: 0.874 ± 0.649
1.311CysGlu: 1.311 ± 0.804
0.437CysPhe: 0.437 ± 0.346
1.748CysGly: 1.748 ± 0.628
0.874CysHis: 0.874 ± 0.631
0.437CysIle: 0.437 ± 0.57
0.874CysLys: 0.874 ± 0.734
1.311CysLeu: 1.311 ± 0.759
0.437CysMet: 0.437 ± 0.527
0.874CysAsn: 0.874 ± 0.484
2.185CysPro: 2.185 ± 0.759
0.874CysGln: 0.874 ± 0.649
1.748CysArg: 1.748 ± 2.281
2.185CysSer: 2.185 ± 1.18
1.311CysThr: 1.311 ± 0.733
1.748CysVal: 1.748 ± 2.011
1.311CysTrp: 1.311 ± 0.474
0.437CysTyr: 0.437 ± 0.346
0.0CysXaa: 0.0 ± 0.0
Asp
3.934AspAla: 3.934 ± 1.454
2.185AspCys: 2.185 ± 1.102
3.497AspAsp: 3.497 ± 0.803
3.497AspGlu: 3.497 ± 1.397
3.497AspPhe: 3.497 ± 0.654
4.371AspGly: 4.371 ± 0.472
0.437AspHis: 0.437 ± 0.443
4.371AspIle: 4.371 ± 2.19
2.622AspLys: 2.622 ± 0.81
6.556AspLeu: 6.556 ± 2.153
0.437AspMet: 0.437 ± 0.367
3.059AspAsn: 3.059 ± 1.53
3.497AspPro: 3.497 ± 1.163
2.622AspGln: 2.622 ± 1.133
3.497AspArg: 3.497 ± 0.538
5.682AspSer: 5.682 ± 1.572
5.245AspThr: 5.245 ± 0.754
6.119AspVal: 6.119 ± 1.854
0.874AspTrp: 0.874 ± 0.434
2.185AspTyr: 2.185 ± 0.913
0.0AspXaa: 0.0 ± 0.0
Glu
6.119GluAla: 6.119 ± 1.347
0.0GluCys: 0.0 ± 0.0
4.808GluAsp: 4.808 ± 0.788
3.934GluGlu: 3.934 ± 1.39
1.748GluPhe: 1.748 ± 0.815
2.622GluGly: 2.622 ± 1.077
3.059GluHis: 3.059 ± 0.67
2.622GluIle: 2.622 ± 0.739
1.748GluLys: 1.748 ± 1.525
3.497GluLeu: 3.497 ± 1.225
1.311GluMet: 1.311 ± 0.715
3.059GluAsn: 3.059 ± 1.058
2.622GluPro: 2.622 ± 1.171
3.497GluGln: 3.497 ± 0.654
2.185GluArg: 2.185 ± 1.234
2.622GluSer: 2.622 ± 1.418
4.371GluThr: 4.371 ± 1.356
4.371GluVal: 4.371 ± 1.129
0.437GluTrp: 0.437 ± 0.346
0.437GluTyr: 0.437 ± 0.367
0.0GluXaa: 0.0 ± 0.0
Phe
2.185PheAla: 2.185 ± 0.88
1.311PheCys: 1.311 ± 0.601
2.185PheAsp: 2.185 ± 0.83
4.371PheGlu: 4.371 ± 1.464
2.622PhePhe: 2.622 ± 1.303
2.622PheGly: 2.622 ± 0.521
0.0PheHis: 0.0 ± 0.0
1.311PheIle: 1.311 ± 0.653
3.059PheLys: 3.059 ± 1.044
5.245PheLeu: 5.245 ± 1.058
1.311PheMet: 1.311 ± 0.653
0.874PheAsn: 0.874 ± 0.734
3.059PhePro: 3.059 ± 0.538
0.437PheGln: 0.437 ± 0.367
1.748PheArg: 1.748 ± 0.613
3.934PheSer: 3.934 ± 1.093
3.059PheThr: 3.059 ± 1.248
3.059PheVal: 3.059 ± 1.118
1.311PheTrp: 1.311 ± 0.726
1.748PheTyr: 1.748 ± 0.509
0.0PheXaa: 0.0 ± 0.0
Gly
3.934GlyAla: 3.934 ± 1.95
2.622GlyCys: 2.622 ± 1.357
3.934GlyAsp: 3.934 ± 1.546
6.119GlyGlu: 6.119 ± 2.374
1.748GlyPhe: 1.748 ± 0.613
8.741GlyGly: 8.741 ± 3.522
1.748GlyHis: 1.748 ± 0.696
3.497GlyIle: 3.497 ± 0.694
1.748GlyLys: 1.748 ± 1.008
6.556GlyLeu: 6.556 ± 1.738
0.0GlyMet: 0.0 ± 0.0
5.245GlyAsn: 5.245 ± 1.425
6.993GlyPro: 6.993 ± 2.247
1.748GlyGln: 1.748 ± 0.575
7.43GlyArg: 7.43 ± 1.74
5.245GlySer: 5.245 ± 0.742
8.304GlyThr: 8.304 ± 2.342
4.371GlyVal: 4.371 ± 1.328
0.874GlyTrp: 0.874 ± 0.692
0.874GlyTyr: 0.874 ± 0.649
0.0GlyXaa: 0.0 ± 0.0
His
1.311HisAla: 1.311 ± 0.474
1.748HisCys: 1.748 ± 1.141
0.0HisAsp: 0.0 ± 0.0
1.748HisGlu: 1.748 ± 0.591
0.874HisPhe: 0.874 ± 0.631
2.622HisGly: 2.622 ± 1.182
0.0HisHis: 0.0 ± 0.0
1.748HisIle: 1.748 ± 0.559
0.437HisLys: 0.437 ± 0.443
1.311HisLeu: 1.311 ± 1.048
0.437HisMet: 0.437 ± 0.346
0.437HisAsn: 0.437 ± 0.381
1.748HisPro: 1.748 ± 0.853
0.874HisGln: 0.874 ± 0.484
0.874HisArg: 0.874 ± 0.692
0.874HisSer: 0.874 ± 0.484
1.311HisThr: 1.311 ± 1.328
0.874HisVal: 0.874 ± 0.434
0.874HisTrp: 0.874 ± 0.434
0.437HisTyr: 0.437 ± 0.381
0.0HisXaa: 0.0 ± 0.0
Ile
1.311IleAla: 1.311 ± 0.653
0.0IleCys: 0.0 ± 0.0
3.059IleAsp: 3.059 ± 1.488
3.497IleGlu: 3.497 ± 1.069
1.311IlePhe: 1.311 ± 1.144
4.808IleGly: 4.808 ± 2.187
0.874IleHis: 0.874 ± 0.407
3.059IleIle: 3.059 ± 1.859
1.748IleLys: 1.748 ± 0.908
3.497IleLeu: 3.497 ± 1.622
0.874IleMet: 0.874 ± 0.434
1.748IleAsn: 1.748 ± 0.853
2.185IlePro: 2.185 ± 0.956
1.748IleGln: 1.748 ± 0.785
1.311IleArg: 1.311 ± 0.709
2.622IleSer: 2.622 ± 0.455
2.185IleThr: 2.185 ± 0.952
2.622IleVal: 2.622 ± 1.348
0.0IleTrp: 0.0 ± 0.0
1.311IleTyr: 1.311 ± 0.437
0.0IleXaa: 0.0 ± 0.0
Lys
0.874LysAla: 0.874 ± 0.885
1.311LysCys: 1.311 ± 0.665
2.185LysAsp: 2.185 ± 0.794
2.622LysGlu: 2.622 ± 0.947
2.185LysPhe: 2.185 ± 1.109
5.245LysGly: 5.245 ± 2.171
1.748LysHis: 1.748 ± 1.014
0.874LysIle: 0.874 ± 0.763
2.185LysLys: 2.185 ± 0.884
3.497LysLeu: 3.497 ± 1.209
0.437LysMet: 0.437 ± 0.686
0.437LysAsn: 0.437 ± 0.443
1.311LysPro: 1.311 ± 0.695
3.497LysGln: 3.497 ± 1.321
3.059LysArg: 3.059 ± 0.452
2.622LysSer: 2.622 ± 1.257
3.059LysThr: 3.059 ± 0.948
2.622LysVal: 2.622 ± 0.805
0.437LysTrp: 0.437 ± 0.367
2.185LysTyr: 2.185 ± 0.852
0.0LysXaa: 0.0 ± 0.0
Leu
4.371LeuAla: 4.371 ± 0.806
1.748LeuCys: 1.748 ± 1.469
8.741LeuAsp: 8.741 ± 1.879
3.934LeuGlu: 3.934 ± 1.01
6.556LeuPhe: 6.556 ± 2.85
8.304LeuGly: 8.304 ± 1.803
2.622LeuHis: 2.622 ± 0.886
3.497LeuIle: 3.497 ± 1.326
5.245LeuLys: 5.245 ± 1.259
6.119LeuLeu: 6.119 ± 1.67
0.874LeuMet: 0.874 ± 0.873
0.437LeuAsn: 0.437 ± 0.443
3.059LeuPro: 3.059 ± 1.264
4.808LeuGln: 4.808 ± 1.095
3.497LeuArg: 3.497 ± 0.666
6.119LeuSer: 6.119 ± 0.789
4.808LeuThr: 4.808 ± 1.72
6.556LeuVal: 6.556 ± 2.427
0.437LeuTrp: 0.437 ± 0.57
3.059LeuTyr: 3.059 ± 1.305
0.0LeuXaa: 0.0 ± 0.0
Met
0.874MetAla: 0.874 ± 0.434
1.311MetCys: 1.311 ± 0.887
1.311MetAsp: 1.311 ± 0.653
0.0MetGlu: 0.0 ± 0.0
0.874MetPhe: 0.874 ± 0.434
0.437MetGly: 0.437 ± 0.367
0.437MetHis: 0.437 ± 0.443
0.0MetIle: 0.0 ± 0.0
0.437MetLys: 0.437 ± 0.346
0.874MetLeu: 0.874 ± 0.705
0.0MetMet: 0.0 ± 0.0
1.748MetAsn: 1.748 ± 0.696
0.874MetPro: 0.874 ± 0.484
0.437MetGln: 0.437 ± 0.367
0.874MetArg: 0.874 ± 0.407
0.874MetSer: 0.874 ± 0.692
0.874MetThr: 0.874 ± 0.72
1.748MetVal: 1.748 ± 0.252
0.437MetTrp: 0.437 ± 0.367
0.874MetTyr: 0.874 ± 0.484
0.0MetXaa: 0.0 ± 0.0
Asn
1.311AsnAla: 1.311 ± 0.474
0.437AsnCys: 0.437 ± 0.381
2.622AsnAsp: 2.622 ± 1.303
1.748AsnGlu: 1.748 ± 0.66
3.497AsnPhe: 3.497 ± 1.405
2.622AsnGly: 2.622 ± 0.945
0.437AsnHis: 0.437 ± 0.346
0.874AsnIle: 0.874 ± 0.763
1.748AsnLys: 1.748 ± 0.613
2.622AsnLeu: 2.622 ± 0.554
0.437AsnMet: 0.437 ± 0.367
1.311AsnAsn: 1.311 ± 0.369
3.497AsnPro: 3.497 ± 1.789
0.874AsnGln: 0.874 ± 0.434
3.497AsnArg: 3.497 ± 1.056
4.808AsnSer: 4.808 ± 1.747
3.059AsnThr: 3.059 ± 1.268
1.748AsnVal: 1.748 ± 0.613
0.437AsnTrp: 0.437 ± 0.346
0.874AsnTyr: 0.874 ± 0.692
0.0AsnXaa: 0.0 ± 0.0
Pro
3.059ProAla: 3.059 ± 2.368
0.874ProCys: 0.874 ± 0.734
7.43ProAsp: 7.43 ± 2.448
3.934ProGlu: 3.934 ± 1.579
1.311ProPhe: 1.311 ± 0.733
3.934ProGly: 3.934 ± 1.79
0.0ProHis: 0.0 ± 0.0
3.497ProIle: 3.497 ± 1.297
2.622ProLys: 2.622 ± 1.045
6.556ProLeu: 6.556 ± 1.815
0.437ProMet: 0.437 ± 0.346
2.622ProAsn: 2.622 ± 1.045
6.993ProPro: 6.993 ± 1.17
3.059ProGln: 3.059 ± 0.969
4.808ProArg: 4.808 ± 1.62
3.934ProSer: 3.934 ± 1.456
3.934ProThr: 3.934 ± 2.019
1.748ProVal: 1.748 ± 0.613
0.437ProTrp: 0.437 ± 0.443
1.748ProTyr: 1.748 ± 0.819
0.0ProXaa: 0.0 ± 0.0
Gln
2.185GlnAla: 2.185 ± 0.745
1.748GlnCys: 1.748 ± 0.687
2.622GlnAsp: 2.622 ± 1.296
1.748GlnGlu: 1.748 ± 1.014
1.748GlnPhe: 1.748 ± 0.575
3.059GlnGly: 3.059 ± 1.021
0.874GlnHis: 0.874 ± 0.692
1.748GlnIle: 1.748 ± 1.259
1.748GlnLys: 1.748 ± 0.696
3.934GlnLeu: 3.934 ± 1.413
0.437GlnMet: 0.437 ± 0.367
2.622GlnAsn: 2.622 ± 1.78
2.185GlnPro: 2.185 ± 0.582
1.311GlnGln: 1.311 ± 0.369
2.185GlnArg: 2.185 ± 0.619
1.748GlnSer: 1.748 ± 1.008
1.748GlnThr: 1.748 ± 0.869
4.371GlnVal: 4.371 ± 1.048
0.874GlnTrp: 0.874 ± 0.484
1.748GlnTyr: 1.748 ± 1.192
0.0GlnXaa: 0.0 ± 0.0
Arg
3.934ArgAla: 3.934 ± 1.503
1.748ArgCys: 1.748 ± 0.735
3.497ArgAsp: 3.497 ± 1.506
2.185ArgGlu: 2.185 ± 1.106
3.059ArgPhe: 3.059 ± 1.093
3.059ArgGly: 3.059 ± 1.038
3.059ArgHis: 3.059 ± 1.32
0.437ArgIle: 0.437 ± 0.381
3.497ArgLys: 3.497 ± 0.625
6.993ArgLeu: 6.993 ± 0.945
1.311ArgMet: 1.311 ± 0.58
2.622ArgAsn: 2.622 ± 0.967
3.497ArgPro: 3.497 ± 0.654
2.622ArgGln: 2.622 ± 1.046
10.052ArgArg: 10.052 ± 3.117
3.059ArgSer: 3.059 ± 0.762
3.497ArgThr: 3.497 ± 1.251
6.556ArgVal: 6.556 ± 1.617
0.0ArgTrp: 0.0 ± 0.0
3.059ArgTyr: 3.059 ± 0.854
0.0ArgXaa: 0.0 ± 0.0
Ser
4.808SerAla: 4.808 ± 1.863
0.874SerCys: 0.874 ± 0.72
3.497SerAsp: 3.497 ± 0.777
2.185SerGlu: 2.185 ± 1.567
4.371SerPhe: 4.371 ± 1.44
6.993SerGly: 6.993 ± 1.309
0.437SerHis: 0.437 ± 0.346
2.185SerIle: 2.185 ± 0.959
2.185SerLys: 2.185 ± 1.014
8.304SerLeu: 8.304 ± 1.89
0.874SerMet: 0.874 ± 0.407
3.497SerAsn: 3.497 ± 1.677
3.934SerPro: 3.934 ± 0.776
3.497SerGln: 3.497 ± 1.233
2.622SerArg: 2.622 ± 1.199
6.119SerSer: 6.119 ± 2.764
7.867SerThr: 7.867 ± 1.228
5.682SerVal: 5.682 ± 1.67
0.437SerTrp: 0.437 ± 0.346
1.311SerTyr: 1.311 ± 0.715
0.0SerXaa: 0.0 ± 0.0
Thr
2.185ThrAla: 2.185 ± 0.711
1.311ThrCys: 1.311 ± 0.683
5.682ThrAsp: 5.682 ± 1.264
3.497ThrGlu: 3.497 ± 1.056
3.059ThrPhe: 3.059 ± 0.823
8.304ThrGly: 8.304 ± 1.957
2.185ThrHis: 2.185 ± 0.83
3.497ThrIle: 3.497 ± 1.358
0.874ThrLys: 0.874 ± 0.885
5.682ThrLeu: 5.682 ± 1.661
1.311ThrMet: 1.311 ± 0.873
2.185ThrAsn: 2.185 ± 0.719
6.119ThrPro: 6.119 ± 0.678
1.748ThrGln: 1.748 ± 1.008
6.119ThrArg: 6.119 ± 1.977
6.119ThrSer: 6.119 ± 2.1
5.245ThrThr: 5.245 ± 1.675
6.119ThrVal: 6.119 ± 1.958
0.437ThrTrp: 0.437 ± 0.443
0.874ThrTyr: 0.874 ± 0.407
0.0ThrXaa: 0.0 ± 0.0
Val
4.808ValAla: 4.808 ± 0.528
1.311ValCys: 1.311 ± 0.601
6.119ValAsp: 6.119 ± 0.828
2.622ValGlu: 2.622 ± 0.655
3.059ValPhe: 3.059 ± 0.731
6.119ValGly: 6.119 ± 2.029
1.311ValHis: 1.311 ± 1.014
3.497ValIle: 3.497 ± 1.024
2.622ValLys: 2.622 ± 0.727
2.622ValLeu: 2.622 ± 0.911
1.748ValMet: 1.748 ± 0.625
2.622ValAsn: 2.622 ± 0.54
4.808ValPro: 4.808 ± 1.703
3.934ValGln: 3.934 ± 1.093
4.808ValArg: 4.808 ± 1.915
7.867ValSer: 7.867 ± 1.883
5.245ValThr: 5.245 ± 2.151
3.497ValVal: 3.497 ± 1.144
1.311ValTrp: 1.311 ± 0.873
2.622ValTyr: 2.622 ± 1.506
0.0ValXaa: 0.0 ± 0.0
Trp
0.874TrpAla: 0.874 ± 0.692
0.0TrpCys: 0.0 ± 0.0
0.874TrpAsp: 0.874 ± 0.434
0.437TrpGlu: 0.437 ± 0.367
0.0TrpPhe: 0.0 ± 0.0
0.874TrpGly: 0.874 ± 0.502
0.0TrpHis: 0.0 ± 0.0
0.437TrpIle: 0.437 ± 0.346
0.437TrpLys: 0.437 ± 0.346
1.748TrpLeu: 1.748 ± 0.869
0.0TrpMet: 0.0 ± 0.0
0.874TrpAsn: 0.874 ± 0.434
0.437TrpPro: 0.437 ± 0.367
0.437TrpGln: 0.437 ± 0.443
1.311TrpArg: 1.311 ± 0.733
0.437TrpSer: 0.437 ± 0.443
1.311TrpThr: 1.311 ± 0.86
1.311TrpVal: 1.311 ± 0.715
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.311TyrAla: 1.311 ± 0.726
0.0TyrCys: 0.0 ± 0.0
2.185TyrAsp: 2.185 ± 0.905
1.748TyrGlu: 1.748 ± 1.29
1.748TyrPhe: 1.748 ± 0.613
2.622TyrGly: 2.622 ± 0.636
0.0TyrHis: 0.0 ± 0.0
0.437TyrIle: 0.437 ± 0.367
3.059TyrLys: 3.059 ± 1.044
3.497TyrLeu: 3.497 ± 1.019
0.874TyrMet: 0.874 ± 0.484
0.874TyrAsn: 0.874 ± 0.427
0.0TyrPro: 0.0 ± 0.0
0.874TyrGln: 0.874 ± 0.434
2.622TyrArg: 2.622 ± 0.711
0.874TyrSer: 0.874 ± 0.483
1.748TyrThr: 1.748 ± 0.575
2.185TyrVal: 2.185 ± 0.952
0.437TyrTrp: 0.437 ± 0.443
3.497TyrTyr: 3.497 ± 1.084
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2289 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski