Amino acid dipepetide frequency for Avian infectious bursal disease virus (strain Chicken/Cuba/Soroa/1998) (IBDV) (Gumboro disease virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.354AlaAla: 8.354 ± 1.923
0.983AlaCys: 0.983 ± 0.173
3.44AlaAsp: 3.44 ± 0.596
3.44AlaGlu: 3.44 ± 1.384
2.457AlaPhe: 2.457 ± 0.466
6.388AlaGly: 6.388 ± 0.423
3.44AlaHis: 3.44 ± 1.414
2.948AlaIle: 2.948 ± 1.357
3.931AlaLys: 3.931 ± 1.138
7.862AlaLeu: 7.862 ± 1.383
4.423AlaMet: 4.423 ± 1.109
5.897AlaAsn: 5.897 ± 1.792
4.914AlaPro: 4.914 ± 0.361
2.457AlaGln: 2.457 ± 0.466
3.44AlaArg: 3.44 ± 0.598
5.897AlaSer: 5.897 ± 1.521
7.371AlaThr: 7.371 ± 1.399
5.405AlaVal: 5.405 ± 0.905
0.491AlaTrp: 0.491 ± 0.392
2.948AlaTyr: 2.948 ± 1.005
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.491CysAsp: 0.491 ± 0.34
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.966CysGly: 1.966 ± 1.981
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.491CysLys: 0.491 ± 0.392
0.983CysLeu: 0.983 ± 1.053
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.983CysPro: 0.983 ± 1.053
0.0CysGln: 0.0 ± 0.0
0.491CysArg: 0.491 ± 0.34
1.474CysSer: 1.474 ± 2.09
0.983CysThr: 0.983 ± 1.053
0.491CysVal: 0.491 ± 0.34
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.44AspAla: 3.44 ± 1.79
1.966AspCys: 1.966 ± 3.161
3.931AspAsp: 3.931 ± 0.534
2.457AspGlu: 2.457 ± 0.466
0.983AspPhe: 0.983 ± 0.173
1.966AspGly: 1.966 ± 0.689
0.0AspHis: 0.0 ± 0.0
2.457AspIle: 2.457 ± 1.273
3.931AspLys: 3.931 ± 1.331
6.388AspLeu: 6.388 ± 2.404
0.491AspMet: 0.491 ± 0.34
1.474AspAsn: 1.474 ± 0.502
5.405AspPro: 5.405 ± 1.188
3.44AspGln: 3.44 ± 0.596
1.966AspArg: 1.966 ± 1.308
1.966AspSer: 1.966 ± 0.346
1.474AspThr: 1.474 ± 1.019
3.44AspVal: 3.44 ± 0.598
0.983AspTrp: 0.983 ± 0.173
3.44AspTyr: 3.44 ± 1.052
0.0AspXaa: 0.0 ± 0.0
Glu
6.88GluAla: 6.88 ± 2.11
0.0GluCys: 0.0 ± 0.0
3.931GluAsp: 3.931 ± 0.691
3.44GluGlu: 3.44 ± 0.793
1.966GluPhe: 1.966 ± 0.885
3.931GluGly: 3.931 ± 0.691
0.0GluHis: 0.0 ± 0.0
2.457GluIle: 2.457 ± 1.699
3.931GluLys: 3.931 ± 0.691
5.405GluLeu: 5.405 ± 0.351
1.474GluMet: 1.474 ± 0.551
1.966GluAsn: 1.966 ± 0.885
2.457GluPro: 2.457 ± 1.938
1.966GluGln: 1.966 ± 0.346
2.948GluArg: 2.948 ± 1.005
2.948GluSer: 2.948 ± 1.973
3.931GluThr: 3.931 ± 0.691
3.931GluVal: 3.931 ± 0.72
1.474GluTrp: 1.474 ± 0.502
2.457GluTyr: 2.457 ± 0.466
0.0GluXaa: 0.0 ± 0.0
Phe
1.966PheAla: 1.966 ± 0.689
0.491PheCys: 0.491 ± 0.392
2.457PheAsp: 2.457 ± 1.536
2.457PheGlu: 2.457 ± 1.273
0.491PhePhe: 0.491 ± 0.34
1.474PheGly: 1.474 ± 0.502
0.0PheHis: 0.0 ± 0.0
2.457PheIle: 2.457 ± 1.021
1.966PheLys: 1.966 ± 0.346
2.457PheLeu: 2.457 ± 1.273
0.983PheMet: 0.983 ± 0.679
2.457PheAsn: 2.457 ± 1.273
4.423PhePro: 4.423 ± 0.668
1.474PheGln: 1.474 ± 1.019
2.457PheArg: 2.457 ± 1.021
0.983PheSer: 0.983 ± 0.679
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.88GlyAla: 6.88 ± 2.103
0.983GlyCys: 0.983 ± 1.053
3.931GlyAsp: 3.931 ± 0.691
4.914GlyGlu: 4.914 ± 0.665
2.457GlyPhe: 2.457 ± 0.466
4.914GlyGly: 4.914 ± 0.361
1.474GlyHis: 1.474 ± 1.137
3.931GlyIle: 3.931 ± 0.691
0.983GlyLys: 0.983 ± 0.173
6.88GlyLeu: 6.88 ± 1.585
0.491GlyMet: 0.491 ± 0.392
3.44GlyAsn: 3.44 ± 1.695
3.44GlyPro: 3.44 ± 1.695
3.931GlyGln: 3.931 ± 1.656
5.405GlyArg: 5.405 ± 1.208
4.914GlySer: 4.914 ± 1.418
3.931GlyThr: 3.931 ± 0.824
6.388GlyVal: 6.388 ± 1.843
1.474GlyTrp: 1.474 ± 1.177
3.44GlyTyr: 3.44 ± 0.598
0.0GlyXaa: 0.0 ± 0.0
His
0.983HisAla: 0.983 ± 0.679
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.474HisGly: 1.474 ± 1.019
0.491HisHis: 0.491 ± 1.073
0.0HisIle: 0.0 ± 0.0
0.983HisLys: 0.983 ± 1.053
2.457HisLeu: 2.457 ± 1.273
0.491HisMet: 0.491 ± 0.392
0.983HisAsn: 0.983 ± 0.679
0.491HisPro: 0.491 ± 1.073
0.0HisGln: 0.0 ± 0.0
3.44HisArg: 3.44 ± 1.414
2.457HisSer: 2.457 ± 3.13
1.966HisThr: 1.966 ± 3.161
0.491HisVal: 0.491 ± 0.34
0.0HisTrp: 0.0 ± 0.0
0.491HisTyr: 0.491 ± 0.34
0.0HisXaa: 0.0 ± 0.0
Ile
3.931IleAla: 3.931 ± 1.138
0.0IleCys: 0.0 ± 0.0
2.457IleAsp: 2.457 ± 0.466
3.44IleGlu: 3.44 ± 1.384
0.0IlePhe: 0.0 ± 0.0
2.948IleGly: 2.948 ± 0.739
0.983IleHis: 0.983 ± 0.679
0.491IleIle: 0.491 ± 0.34
2.948IleLys: 2.948 ± 0.518
2.948IleLeu: 2.948 ± 0.518
0.983IleMet: 0.983 ± 0.173
2.948IleAsn: 2.948 ± 0.518
3.931IlePro: 3.931 ± 1.694
0.0IleGln: 0.0 ± 0.0
3.931IleArg: 3.931 ± 1.377
1.966IleSer: 1.966 ± 0.885
4.423IleThr: 4.423 ± 1.708
3.931IleVal: 3.931 ± 1.377
0.491IleTrp: 0.491 ± 0.392
2.948IleTyr: 2.948 ± 0.518
0.0IleXaa: 0.0 ± 0.0
Lys
4.914LysAla: 4.914 ± 2.546
0.0LysCys: 0.0 ± 0.0
3.44LysAsp: 3.44 ± 0.598
2.457LysGlu: 2.457 ± 1.273
1.474LysPhe: 1.474 ± 0.502
2.948LysGly: 2.948 ± 1.664
1.474LysHis: 1.474 ± 1.137
1.966LysIle: 1.966 ± 0.346
1.474LysLys: 1.474 ± 0.502
4.423LysLeu: 4.423 ± 1.507
1.966LysMet: 1.966 ± 0.689
1.966LysAsn: 1.966 ± 0.885
5.897LysPro: 5.897 ± 2.113
0.983LysGln: 0.983 ± 0.785
2.948LysArg: 2.948 ± 1.818
4.423LysSer: 4.423 ± 1.507
1.966LysThr: 1.966 ± 0.885
3.931LysVal: 3.931 ± 1.138
0.0LysTrp: 0.0 ± 0.0
1.966LysTyr: 1.966 ± 0.346
0.0LysXaa: 0.0 ± 0.0
Leu
9.337LeuAla: 9.337 ± 1.656
0.491LeuCys: 0.491 ± 1.073
4.423LeuAsp: 4.423 ± 0.995
4.914LeuGlu: 4.914 ± 0.933
4.423LeuPhe: 4.423 ± 0.668
5.897LeuGly: 5.897 ± 1.059
1.474LeuHis: 1.474 ± 1.173
2.948LeuIle: 2.948 ± 0.739
4.914LeuLys: 4.914 ± 3.23
9.828LeuLeu: 9.828 ± 3.731
2.457LeuMet: 2.457 ± 0.466
5.405LeuAsn: 5.405 ± 0.532
7.862LeuPro: 7.862 ± 0.16
4.914LeuGln: 4.914 ± 3.875
4.914LeuArg: 4.914 ± 0.933
9.337LeuSer: 9.337 ± 1.786
6.388LeuThr: 6.388 ± 1.067
7.862LeuVal: 7.862 ± 1.743
0.0LeuTrp: 0.0 ± 0.0
0.491LeuTyr: 0.491 ± 0.392
0.0LeuXaa: 0.0 ± 0.0
Met
1.474MetAla: 1.474 ± 0.37
0.0MetCys: 0.0 ± 0.0
0.491MetAsp: 0.491 ± 0.34
2.457MetGlu: 2.457 ± 1.021
0.983MetPhe: 0.983 ± 0.173
1.474MetGly: 1.474 ± 0.502
0.0MetHis: 0.0 ± 0.0
1.966MetIle: 1.966 ± 1.57
1.474MetLys: 1.474 ± 0.37
1.966MetLeu: 1.966 ± 0.346
0.0MetMet: 0.0 ± 0.0
1.474MetAsn: 1.474 ± 0.502
0.983MetPro: 0.983 ± 0.679
0.491MetGln: 0.491 ± 0.392
1.474MetArg: 1.474 ± 0.502
1.966MetSer: 1.966 ± 0.346
1.474MetThr: 1.474 ± 1.019
0.983MetVal: 0.983 ± 1.052
0.491MetTrp: 0.491 ± 0.34
0.491MetTyr: 0.491 ± 0.392
0.0MetXaa: 0.0 ± 0.0
Asn
5.405AsnAla: 5.405 ± 0.905
1.474AsnCys: 1.474 ± 2.09
0.983AsnAsp: 0.983 ± 1.052
2.457AsnGlu: 2.457 ± 0.641
1.966AsnPhe: 1.966 ± 0.689
3.931AsnGly: 3.931 ± 1.377
0.983AsnHis: 0.983 ± 0.173
3.931AsnIle: 3.931 ± 1.769
2.948AsnLys: 2.948 ± 1.664
6.388AsnLeu: 6.388 ± 2.396
0.0AsnMet: 0.0 ± 0.0
2.457AsnAsn: 2.457 ± 1.09
4.423AsnPro: 4.423 ± 0.458
1.474AsnGln: 1.474 ± 0.502
1.966AsnArg: 1.966 ± 1.396
2.457AsnSer: 2.457 ± 0.466
1.474AsnThr: 1.474 ± 0.502
1.966AsnVal: 1.966 ± 0.346
0.491AsnTrp: 0.491 ± 0.34
2.457AsnTyr: 2.457 ± 1.021
0.0AsnXaa: 0.0 ± 0.0
Pro
3.44ProAla: 3.44 ± 0.818
0.0ProCys: 0.0 ± 0.0
4.423ProAsp: 4.423 ± 0.995
5.897ProGlu: 5.897 ± 1.62
1.474ProPhe: 1.474 ± 0.37
6.88ProGly: 6.88 ± 2.884
0.491ProHis: 0.491 ± 0.34
3.44ProIle: 3.44 ± 1.695
6.88ProLys: 6.88 ± 1.585
4.423ProLeu: 4.423 ± 0.952
0.983ProMet: 0.983 ± 0.785
5.405ProAsn: 5.405 ± 1.188
5.405ProPro: 5.405 ± 0.905
2.457ProGln: 2.457 ± 0.466
2.948ProArg: 2.948 ± 0.707
3.931ProSer: 3.931 ± 1.331
6.388ProThr: 6.388 ± 0.312
5.405ProVal: 5.405 ± 0.991
1.474ProTrp: 1.474 ± 2.09
1.474ProTyr: 1.474 ± 0.37
0.0ProXaa: 0.0 ± 0.0
Gln
5.405GlnAla: 5.405 ± 0.351
0.0GlnCys: 0.0 ± 0.0
0.983GlnAsp: 0.983 ± 0.785
0.983GlnGlu: 0.983 ± 0.173
1.474GlnPhe: 1.474 ± 0.909
1.966GlnGly: 1.966 ± 0.346
0.491GlnHis: 0.491 ± 0.392
2.457GlnIle: 2.457 ± 0.641
0.491GlnLys: 0.491 ± 0.392
2.457GlnLeu: 2.457 ± 1.938
2.457GlnMet: 2.457 ± 0.502
1.966GlnAsn: 1.966 ± 0.689
2.948GlnPro: 2.948 ± 0.518
0.491GlnGln: 0.491 ± 0.34
2.457GlnArg: 2.457 ± 1.021
1.474GlnSer: 1.474 ± 0.502
1.966GlnThr: 1.966 ± 0.923
2.457GlnVal: 2.457 ± 1.927
0.983GlnTrp: 0.983 ± 1.053
0.983GlnTyr: 0.983 ± 0.679
0.0GlnXaa: 0.0 ± 0.0
Arg
4.914ArgAla: 4.914 ± 2.303
0.0ArgCys: 0.0 ± 0.0
3.44ArgAsp: 3.44 ± 2.968
3.931ArgGlu: 3.931 ± 1.377
0.983ArgPhe: 0.983 ± 0.679
4.423ArgGly: 4.423 ± 1.109
1.474ArgHis: 1.474 ± 2.09
1.966ArgIle: 1.966 ± 0.689
0.491ArgLys: 0.491 ± 1.073
6.88ArgLeu: 6.88 ± 0.744
0.983ArgMet: 0.983 ± 0.173
2.457ArgAsn: 2.457 ± 0.641
3.931ArgPro: 3.931 ± 0.691
4.423ArgGln: 4.423 ± 2.157
2.457ArgArg: 2.457 ± 0.749
6.88ArgSer: 6.88 ± 2.386
2.457ArgThr: 2.457 ± 0.975
2.457ArgVal: 2.457 ± 0.975
0.491ArgTrp: 0.491 ± 0.34
1.474ArgTyr: 1.474 ± 1.177
0.0ArgXaa: 0.0 ± 0.0
Ser
4.914SerAla: 4.914 ± 0.864
0.983SerCys: 0.983 ± 0.785
5.897SerAsp: 5.897 ± 2.533
6.388SerGlu: 6.388 ± 2.404
0.983SerPhe: 0.983 ± 0.679
6.388SerGly: 6.388 ± 0.423
0.491SerHis: 0.491 ± 1.073
4.423SerIle: 4.423 ± 0.747
5.405SerLys: 5.405 ± 1.115
5.897SerLeu: 5.897 ± 0.19
0.983SerMet: 0.983 ± 0.785
3.931SerAsn: 3.931 ± 2.01
3.931SerPro: 3.931 ± 1.138
1.966SerGln: 1.966 ± 1.308
3.931SerArg: 3.931 ± 1.331
3.44SerSer: 3.44 ± 0.793
4.423SerThr: 4.423 ± 0.952
2.948SerVal: 2.948 ± 1.166
0.983SerTrp: 0.983 ± 1.052
1.474SerTyr: 1.474 ± 1.019
0.0SerXaa: 0.0 ± 0.0
Thr
5.405ThrAla: 5.405 ± 1.208
0.491ThrCys: 0.491 ± 0.34
2.457ThrAsp: 2.457 ± 1.021
0.983ThrGlu: 0.983 ± 1.052
2.457ThrPhe: 2.457 ± 0.641
6.88ThrGly: 6.88 ± 1.241
0.983ThrHis: 0.983 ± 0.785
3.44ThrIle: 3.44 ± 1.052
2.948ThrLys: 2.948 ± 0.81
7.862ThrLeu: 7.862 ± 1.647
0.491ThrMet: 0.491 ± 0.34
1.474ThrAsn: 1.474 ± 1.137
2.457ThrPro: 2.457 ± 1.021
1.966ThrGln: 1.966 ± 0.689
3.931ThrArg: 3.931 ± 1.138
5.897ThrSer: 5.897 ± 0.816
1.966ThrThr: 1.966 ± 1.359
5.405ThrVal: 5.405 ± 2.377
1.966ThrTrp: 1.966 ± 1.57
1.966ThrTyr: 1.966 ± 0.885
0.0ThrXaa: 0.0 ± 0.0
Val
6.388ValAla: 6.388 ± 2.396
0.0ValCys: 0.0 ± 0.0
2.457ValAsp: 2.457 ± 0.466
4.423ValGlu: 4.423 ± 2.157
2.457ValPhe: 2.457 ± 1.021
4.914ValGly: 4.914 ± 0.864
2.457ValHis: 2.457 ± 1.927
1.966ValIle: 1.966 ± 1.359
2.457ValLys: 2.457 ± 1.09
6.88ValLeu: 6.88 ± 1.585
0.491ValMet: 0.491 ± 0.392
1.474ValAsn: 1.474 ± 0.502
5.405ValPro: 5.405 ± 1.115
0.983ValGln: 0.983 ± 0.785
4.423ValArg: 4.423 ± 4.016
3.931ValSer: 3.931 ± 1.694
5.405ValThr: 5.405 ± 2.377
4.423ValVal: 4.423 ± 1.109
1.474ValTrp: 1.474 ± 0.37
2.948ValTyr: 2.948 ± 0.739
0.0ValXaa: 0.0 ± 0.0
Trp
0.983TrpAla: 0.983 ± 0.173
0.0TrpCys: 0.0 ± 0.0
0.983TrpAsp: 0.983 ± 0.679
0.491TrpGlu: 0.491 ± 1.073
0.491TrpPhe: 0.491 ± 0.392
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.474TrpIle: 1.474 ± 0.909
0.0TrpLys: 0.0 ± 0.0
1.474TrpLeu: 1.474 ± 0.909
0.491TrpMet: 0.491 ± 0.392
0.983TrpAsn: 0.983 ± 0.785
0.983TrpPro: 0.983 ± 0.173
0.491TrpGln: 0.491 ± 0.34
0.491TrpArg: 0.491 ± 1.073
2.457TrpSer: 2.457 ± 1.273
0.0TrpThr: 0.0 ± 0.0
1.474TrpVal: 1.474 ± 0.502
0.491TrpTrp: 0.491 ± 1.073
0.983TrpTyr: 0.983 ± 0.785
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.474TyrAla: 1.474 ± 0.37
0.491TyrCys: 0.491 ± 0.34
0.983TyrAsp: 0.983 ± 0.173
2.457TyrGlu: 2.457 ± 0.466
1.474TyrPhe: 1.474 ± 0.37
3.44TyrGly: 3.44 ± 1.052
0.491TyrHis: 0.491 ± 0.34
0.983TyrIle: 0.983 ± 0.785
1.966TyrLys: 1.966 ± 0.885
4.423TyrLeu: 4.423 ± 0.747
0.983TyrMet: 0.983 ± 0.173
1.474TyrAsn: 1.474 ± 1.019
2.948TyrPro: 2.948 ± 1.664
0.983TyrGln: 0.983 ± 0.679
0.491TyrArg: 0.491 ± 0.392
0.983TyrSer: 0.983 ± 0.785
3.44TyrThr: 3.44 ± 1.052
1.966TyrVal: 1.966 ± 0.346
0.983TyrTrp: 0.983 ± 0.173
0.983TyrTyr: 0.983 ± 0.785
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2036 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski