Amino acid dipepetide frequency for Bacteroides faecichinchillae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.881AlaAla: 4.881 ± 0.081	0.924AlaCys: 0.924 ± 0.028	3.674AlaAsp: 3.674 ± 0.055	4.281AlaGlu: 4.281 ± 0.063	3.033AlaPhe: 3.033 ± 0.058	4.417AlaGly: 4.417 ± 0.065	1.114AlaHis: 1.114 ± 0.029	4.871AlaIle: 4.871 ± 0.064	4.136AlaLys: 4.136 ± 0.06	6.006AlaLeu: 6.006 ± 0.079	1.815AlaMet: 1.815 ± 0.033	3.203AlaAsn: 3.203 ± 0.046	2.052AlaPro: 2.052 ± 0.041	2.469AlaGln: 2.469 ± 0.042	2.729AlaArg: 2.729 ± 0.046	3.863AlaSer: 3.863 ± 0.049	3.756AlaThr: 3.756 ± 0.055	4.344AlaVal: 4.344 ± 0.065	0.753AlaTrp: 0.753 ± 0.024	2.749AlaTyr: 2.749 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.769CysAla: 0.769 ± 0.027	0.242CysCys: 0.242 ± 0.013	0.656CysAsp: 0.656 ± 0.023	0.691CysGlu: 0.691 ± 0.024	0.671CysPhe: 0.671 ± 0.024	1.049CysGly: 1.049 ± 0.033	0.307CysHis: 0.307 ± 0.015	1.058CysIle: 1.058 ± 0.03	0.801CysLys: 0.801 ± 0.025	1.137CysLeu: 1.137 ± 0.03	0.354CysMet: 0.354 ± 0.016	0.625CysAsn: 0.625 ± 0.024	0.55CysPro: 0.55 ± 0.023	0.386CysGln: 0.386 ± 0.018	0.591CysArg: 0.591 ± 0.022	0.853CysSer: 0.853 ± 0.026	0.706CysThr: 0.706 ± 0.025	0.751CysVal: 0.751 ± 0.024	0.165CysTrp: 0.165 ± 0.01	0.608CysTyr: 0.608 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.388AspAla: 3.388 ± 0.048	0.632AspCys: 0.632 ± 0.022	2.618AspAsp: 2.618 ± 0.05	3.757AspGlu: 3.757 ± 0.059	2.913AspPhe: 2.913 ± 0.043	3.995AspGly: 3.995 ± 0.066	0.868AspHis: 0.868 ± 0.024	4.411AspIle: 4.411 ± 0.059	4.095AspLys: 4.095 ± 0.057	4.567AspLeu: 4.567 ± 0.07	1.6AspMet: 1.6 ± 0.036	2.937AspAsn: 2.937 ± 0.046	1.851AspPro: 1.851 ± 0.039	1.35AspGln: 1.35 ± 0.034	2.382AspArg: 2.382 ± 0.045	3.121AspSer: 3.121 ± 0.06	2.75AspThr: 2.75 ± 0.045	3.41AspVal: 3.41 ± 0.056	0.839AspTrp: 0.839 ± 0.025	2.898AspTyr: 2.898 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.443GluAla: 4.443 ± 0.066	0.676GluCys: 0.676 ± 0.026	3.236GluAsp: 3.236 ± 0.052	5.208GluGlu: 5.208 ± 0.067	2.618GluPhe: 2.618 ± 0.042	4.016GluGly: 4.016 ± 0.059	1.203GluHis: 1.203 ± 0.029	4.892GluIle: 4.892 ± 0.055	5.54GluLys: 5.54 ± 0.066	6.207GluLeu: 6.207 ± 0.061	2.046GluMet: 2.046 ± 0.043	3.728GluAsn: 3.728 ± 0.055	1.737GluPro: 1.737 ± 0.04	2.644GluGln: 2.644 ± 0.051	3.202GluArg: 3.202 ± 0.052	3.302GluSer: 3.302 ± 0.056	3.359GluThr: 3.359 ± 0.06	4.285GluVal: 4.285 ± 0.059	0.87GluTrp: 0.87 ± 0.024	2.989GluTyr: 2.989 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	2.839PheAla: 2.839 ± 0.046	0.745PheCys: 0.745 ± 0.024	2.722PheAsp: 2.722 ± 0.052	2.58PheGlu: 2.58 ± 0.038	2.279PhePhe: 2.279 ± 0.055	3.126PheGly: 3.126 ± 0.055	0.922PheHis: 0.922 ± 0.027	3.631PheIle: 3.631 ± 0.064	2.527PheLys: 2.527 ± 0.046	4.123PheLeu: 4.123 ± 0.073	1.234PheMet: 1.234 ± 0.032	2.47PheAsn: 2.47 ± 0.044	1.789PhePro: 1.789 ± 0.035	1.331PheGln: 1.331 ± 0.031	2.071PheArg: 2.071 ± 0.041	3.526PheSer: 3.526 ± 0.062	2.835PheThr: 2.835 ± 0.051	2.922PheVal: 2.922 ± 0.056	0.573PheTrp: 0.573 ± 0.023	2.112PheTyr: 2.112 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.037GlyAla: 4.037 ± 0.062	0.938GlyCys: 0.938 ± 0.029	3.399GlyAsp: 3.399 ± 0.056	4.044GlyGlu: 4.044 ± 0.061	3.134GlyPhe: 3.134 ± 0.054	4.482GlyGly: 4.482 ± 0.083	1.196GlyHis: 1.196 ± 0.031	5.538GlyIle: 5.538 ± 0.065	5.322GlyLys: 5.322 ± 0.063	5.588GlyLeu: 5.588 ± 0.071	2.06GlyMet: 2.06 ± 0.044	3.648GlyAsn: 3.648 ± 0.069	1.27GlyPro: 1.27 ± 0.032	1.961GlyGln: 1.961 ± 0.041	2.649GlyArg: 2.649 ± 0.044	3.758GlySer: 3.758 ± 0.06	4.035GlyThr: 4.035 ± 0.059	4.492GlyVal: 4.492 ± 0.048	0.952GlyTrp: 0.952 ± 0.027	3.319GlyTyr: 3.319 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.074HisAla: 1.074 ± 0.031	0.34HisCys: 0.34 ± 0.015	0.876HisAsp: 0.876 ± 0.028	1.051HisGlu: 1.051 ± 0.025	1.038HisPhe: 1.038 ± 0.028	1.141HisGly: 1.141 ± 0.03	0.493HisHis: 0.493 ± 0.02	1.444HisIle: 1.444 ± 0.032	1.098HisLys: 1.098 ± 0.029	1.828HisLeu: 1.828 ± 0.039	0.342HisMet: 0.342 ± 0.014	0.873HisAsn: 0.873 ± 0.028	1.098HisPro: 1.098 ± 0.028	0.642HisGln: 0.642 ± 0.019	0.862HisArg: 0.862 ± 0.025	1.219HisSer: 1.219 ± 0.032	1.003HisThr: 1.003 ± 0.027	1.008HisVal: 1.008 ± 0.024	0.271HisTrp: 0.271 ± 0.015	0.941HisTyr: 0.941 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.351IleAla: 5.351 ± 0.066	1.083IleCys: 1.083 ± 0.028	4.543IleAsp: 4.543 ± 0.059	4.764IleGlu: 4.764 ± 0.064	3.078IlePhe: 3.078 ± 0.058	4.903IleGly: 4.903 ± 0.068	1.497IleHis: 1.497 ± 0.033	5.253IleIle: 5.253 ± 0.089	4.643IleLys: 4.643 ± 0.063	6.576IleLeu: 6.576 ± 0.086	1.585IleMet: 1.585 ± 0.038	3.816IleAsn: 3.816 ± 0.059	3.328IlePro: 3.328 ± 0.053	2.555IleGln: 2.555 ± 0.042	3.505IleArg: 3.505 ± 0.052	5.11IleSer: 5.11 ± 0.071	4.288IleThr: 4.288 ± 0.065	4.581IleVal: 4.581 ± 0.064	0.811IleTrp: 0.811 ± 0.028	3.172IleTyr: 3.172 ± 0.053	0.0IleXaa: 0.0 ± 0.0
Lys	4.685LysAla: 4.685 ± 0.074	0.602LysCys: 0.602 ± 0.021	4.288LysAsp: 4.288 ± 0.056	6.31LysGlu: 6.31 ± 0.073	2.27LysPhe: 2.27 ± 0.044	4.538LysGly: 4.538 ± 0.063	1.238LysHis: 1.238 ± 0.03	4.74LysIle: 4.74 ± 0.063	5.694LysLys: 5.694 ± 0.075	5.572LysLeu: 5.572 ± 0.061	2.26LysMet: 2.26 ± 0.04	3.872LysAsn: 3.872 ± 0.056	2.129LysPro: 2.129 ± 0.043	2.727LysGln: 2.727 ± 0.046	3.319LysArg: 3.319 ± 0.052	3.562LysSer: 3.562 ± 0.052	3.539LysThr: 3.539 ± 0.056	4.569LysVal: 4.569 ± 0.061	0.809LysTrp: 0.809 ± 0.027	3.238LysTyr: 3.238 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	5.854LeuAla: 5.854 ± 0.072	1.353LeuCys: 1.353 ± 0.035	4.521LeuAsp: 4.521 ± 0.054	5.222LeuGlu: 5.222 ± 0.07	4.665LeuPhe: 4.665 ± 0.078	5.371LeuGly: 5.371 ± 0.073	1.742LeuHis: 1.742 ± 0.033	6.049LeuIle: 6.049 ± 0.08	6.588LeuLys: 6.588 ± 0.071	9.061LeuLeu: 9.061 ± 0.123	2.494LeuMet: 2.494 ± 0.052	4.823LeuAsn: 4.823 ± 0.064	4.094LeuPro: 4.094 ± 0.052	3.296LeuGln: 3.296 ± 0.052	4.056LeuArg: 4.056 ± 0.056	6.589LeuSer: 6.589 ± 0.075	5.045LeuThr: 5.045 ± 0.064	5.059LeuVal: 5.059 ± 0.071	1.062LeuTrp: 1.062 ± 0.03	3.787LeuTyr: 3.787 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	1.94MetAla: 1.94 ± 0.038	0.268MetCys: 0.268 ± 0.013	1.461MetAsp: 1.461 ± 0.036	1.835MetGlu: 1.835 ± 0.037	1.071MetPhe: 1.071 ± 0.026	1.835MetGly: 1.835 ± 0.036	0.431MetHis: 0.431 ± 0.019	1.792MetIle: 1.792 ± 0.039	2.697MetLys: 2.697 ± 0.04	2.433MetLeu: 2.433 ± 0.044	0.82MetMet: 0.82 ± 0.025	1.715MetAsn: 1.715 ± 0.031	1.069MetPro: 1.069 ± 0.03	0.995MetGln: 0.995 ± 0.033	1.297MetArg: 1.297 ± 0.029	1.526MetSer: 1.526 ± 0.033	1.439MetThr: 1.439 ± 0.027	1.606MetVal: 1.606 ± 0.032	0.239MetTrp: 0.239 ± 0.014	0.934MetTyr: 0.934 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.296AsnAla: 3.296 ± 0.048	0.584AsnCys: 0.584 ± 0.021	2.796AsnAsp: 2.796 ± 0.05	3.436AsnGlu: 3.436 ± 0.048	2.318AsnPhe: 2.318 ± 0.047	4.076AsnGly: 4.076 ± 0.057	0.997AsnHis: 0.997 ± 0.026	4.198AsnIle: 4.198 ± 0.071	3.636AsnLys: 3.636 ± 0.052	4.564AsnLeu: 4.564 ± 0.058	1.362AsnMet: 1.362 ± 0.031	2.867AsnAsn: 2.867 ± 0.057	2.377AsnPro: 2.377 ± 0.044	1.767AsnGln: 1.767 ± 0.039	2.46AsnArg: 2.46 ± 0.049	3.052AsnSer: 3.052 ± 0.053	2.831AsnThr: 2.831 ± 0.047	3.284AsnVal: 3.284 ± 0.055	0.713AsnTrp: 0.713 ± 0.022	2.5AsnTyr: 2.5 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	2.342ProAla: 2.342 ± 0.045	0.381ProCys: 0.381 ± 0.018	2.423ProAsp: 2.423 ± 0.037	3.221ProGlu: 3.221 ± 0.052	1.902ProPhe: 1.902 ± 0.037	2.259ProGly: 2.259 ± 0.037	0.683ProHis: 0.683 ± 0.024	2.619ProIle: 2.619 ± 0.043	2.172ProLys: 2.172 ± 0.036	3.224ProLeu: 3.224 ± 0.056	0.957ProMet: 0.957 ± 0.025	1.85ProAsn: 1.85 ± 0.039	0.829ProPro: 0.829 ± 0.024	1.404ProGln: 1.404 ± 0.034	1.229ProArg: 1.229 ± 0.028	2.329ProSer: 2.329 ± 0.043	2.004ProThr: 2.004 ± 0.039	2.794ProVal: 2.794 ± 0.041	0.422ProTrp: 0.422 ± 0.02	1.784ProTyr: 1.784 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.285GlnAla: 2.285 ± 0.048	0.335GlnCys: 0.335 ± 0.017	1.58GlnAsp: 1.58 ± 0.032	2.439GlnGlu: 2.439 ± 0.036	1.358GlnPhe: 1.358 ± 0.028	1.966GlnGly: 1.966 ± 0.038	0.641GlnHis: 0.641 ± 0.022	2.572GlnIle: 2.572 ± 0.039	2.614GlnLys: 2.614 ± 0.046	3.442GlnLeu: 3.442 ± 0.062	1.008GlnMet: 1.008 ± 0.027	1.798GlnAsn: 1.798 ± 0.039	1.279GlnPro: 1.279 ± 0.035	1.625GlnGln: 1.625 ± 0.039	1.598GlnArg: 1.598 ± 0.035	1.988GlnSer: 1.988 ± 0.039	2.082GlnThr: 2.082 ± 0.045	2.062GlnVal: 2.062 ± 0.04	0.461GlnTrp: 0.461 ± 0.02	1.552GlnTyr: 1.552 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.474ArgAla: 2.474 ± 0.048	0.479ArgCys: 0.479 ± 0.017	2.082ArgAsp: 2.082 ± 0.04	2.888ArgGlu: 2.888 ± 0.049	2.259ArgPhe: 2.259 ± 0.047	2.337ArgGly: 2.337 ± 0.048	0.849ArgHis: 0.849 ± 0.025	3.775ArgIle: 3.775 ± 0.053	3.484ArgLys: 3.484 ± 0.056	4.259ArgLeu: 4.259 ± 0.069	1.451ArgMet: 1.451 ± 0.035	2.469ArgAsn: 2.469 ± 0.047	1.575ArgPro: 1.575 ± 0.039	1.74ArgGln: 1.74 ± 0.035	2.092ArgArg: 2.092 ± 0.045	2.461ArgSer: 2.461 ± 0.045	2.401ArgThr: 2.401 ± 0.044	2.435ArgVal: 2.435 ± 0.042	0.618ArgTrp: 0.618 ± 0.021	2.202ArgTyr: 2.202 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	3.804SerAla: 3.804 ± 0.063	0.973SerCys: 0.973 ± 0.026	3.347SerAsp: 3.347 ± 0.055	3.691SerGlu: 3.691 ± 0.05	3.37SerPhe: 3.37 ± 0.052	4.343SerGly: 4.343 ± 0.066	1.163SerHis: 1.163 ± 0.031	4.728SerIle: 4.728 ± 0.061	3.656SerLys: 3.656 ± 0.055	5.988SerLeu: 5.988 ± 0.067	1.549SerMet: 1.549 ± 0.034	2.993SerAsn: 2.993 ± 0.056	2.345SerPro: 2.345 ± 0.043	1.982SerGln: 1.982 ± 0.04	2.557SerArg: 2.557 ± 0.047	4.168SerSer: 4.168 ± 0.083	3.319SerThr: 3.319 ± 0.051	4.148SerVal: 4.148 ± 0.056	0.831SerTrp: 0.831 ± 0.023	2.978SerTyr: 2.978 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	3.654ThrAla: 3.654 ± 0.053	0.625ThrCys: 0.625 ± 0.021	3.274ThrAsp: 3.274 ± 0.049	3.352ThrGlu: 3.352 ± 0.047	2.775ThrPhe: 2.775 ± 0.049	4.144ThrGly: 4.144 ± 0.06	1.0ThrHis: 1.0 ± 0.025	4.245ThrIle: 4.245 ± 0.06	3.056ThrLys: 3.056 ± 0.052	5.324ThrLeu: 5.324 ± 0.061	1.208ThrMet: 1.208 ± 0.03	2.678ThrAsn: 2.678 ± 0.046	2.704ThrPro: 2.704 ± 0.045	1.765ThrGln: 1.765 ± 0.036	2.094ThrArg: 2.094 ± 0.044	3.555ThrSer: 3.555 ± 0.051	3.126ThrThr: 3.126 ± 0.054	3.88ThrVal: 3.88 ± 0.055	0.685ThrTrp: 0.685 ± 0.023	2.486ThrTyr: 2.486 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	4.339ValAla: 4.339 ± 0.063	0.997ValCys: 0.997 ± 0.03	3.522ValAsp: 3.522 ± 0.05	4.077ValGlu: 4.077 ± 0.056	2.839ValPhe: 2.839 ± 0.047	3.941ValGly: 3.941 ± 0.057	1.091ValHis: 1.091 ± 0.028	4.641ValIle: 4.641 ± 0.066	4.329ValLys: 4.329 ± 0.061	5.476ValLeu: 5.476 ± 0.064	1.649ValMet: 1.649 ± 0.035	3.32ValAsn: 3.32 ± 0.048	2.516ValPro: 2.516 ± 0.037	1.856ValGln: 1.856 ± 0.036	2.819ValArg: 2.819 ± 0.051	4.314ValSer: 4.314 ± 0.066	3.75ValThr: 3.75 ± 0.051	4.233ValVal: 4.233 ± 0.063	0.728ValTrp: 0.728 ± 0.023	2.672ValTyr: 2.672 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.721TrpAla: 0.721 ± 0.024	0.174TrpCys: 0.174 ± 0.012	0.709TrpAsp: 0.709 ± 0.024	0.785TrpGlu: 0.785 ± 0.023	0.572TrpPhe: 0.572 ± 0.017	0.927TrpGly: 0.927 ± 0.025	0.251TrpHis: 0.251 ± 0.013	0.885TrpIle: 0.885 ± 0.03	0.986TrpLys: 0.986 ± 0.03	1.167TrpLeu: 1.167 ± 0.027	0.474TrpMet: 0.474 ± 0.02	0.841TrpAsn: 0.841 ± 0.028	0.288TrpPro: 0.288 ± 0.015	0.49TrpGln: 0.49 ± 0.019	0.552TrpArg: 0.552 ± 0.022	0.681TrpSer: 0.681 ± 0.02	0.671TrpThr: 0.671 ± 0.023	0.697TrpVal: 0.697 ± 0.024	0.192TrpTrp: 0.192 ± 0.012	0.552TrpTyr: 0.552 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.89TyrAla: 2.89 ± 0.05	0.621TyrCys: 0.621 ± 0.023	2.658TyrAsp: 2.658 ± 0.054	2.57TyrGlu: 2.57 ± 0.047	2.193TyrPhe: 2.193 ± 0.037	2.958TyrGly: 2.958 ± 0.048	0.956TyrHis: 0.956 ± 0.028	3.098TyrIle: 3.098 ± 0.049	2.89TyrLys: 2.89 ± 0.048	4.189TyrLeu: 4.189 ± 0.058	1.131TyrMet: 1.131 ± 0.029	2.586TyrAsn: 2.586 ± 0.054	1.948TyrPro: 1.948 ± 0.04	1.699TyrGln: 1.699 ± 0.037	2.269TyrArg: 2.269 ± 0.048	2.957TyrSer: 2.957 ± 0.045	2.69TyrThr: 2.69 ± 0.049	2.55TyrVal: 2.55 ± 0.041	0.619TyrTrp: 0.619 ± 0.022	2.304TyrTyr: 2.304 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4051 proteins (1408408 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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