Amino acid dipepetide frequency for Lysinibacillus odysseyi 34hs-1 = NBRC 100172

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.223AlaAla: 7.223 ± 0.1
0.705AlaCys: 0.705 ± 0.023
3.814AlaAsp: 3.814 ± 0.06
5.432AlaGlu: 5.432 ± 0.076
3.608AlaPhe: 3.608 ± 0.055
5.709AlaGly: 5.709 ± 0.081
1.423AlaHis: 1.423 ± 0.039
6.465AlaIle: 6.465 ± 0.08
4.894AlaLys: 4.894 ± 0.068
7.834AlaLeu: 7.834 ± 0.098
2.235AlaMet: 2.235 ± 0.042
2.865AlaAsn: 2.865 ± 0.051
2.224AlaPro: 2.224 ± 0.051
2.619AlaGln: 2.619 ± 0.05
2.969AlaArg: 2.969 ± 0.053
4.235AlaSer: 4.235 ± 0.068
3.749AlaThr: 3.749 ± 0.062
6.17AlaVal: 6.17 ± 0.08
0.664AlaTrp: 0.664 ± 0.022
2.648AlaTyr: 2.648 ± 0.054
0.0AlaXaa: 0.0 ± 0.0
Cys
0.468CysAla: 0.468 ± 0.022
0.111CysCys: 0.111 ± 0.011
0.352CysAsp: 0.352 ± 0.016
0.473CysGlu: 0.473 ± 0.022
0.354CysPhe: 0.354 ± 0.018
0.677CysGly: 0.677 ± 0.026
0.174CysHis: 0.174 ± 0.012
0.653CysIle: 0.653 ± 0.026
0.365CysLys: 0.365 ± 0.017
0.699CysLeu: 0.699 ± 0.027
0.202CysMet: 0.202 ± 0.015
0.296CysAsn: 0.296 ± 0.016
0.336CysPro: 0.336 ± 0.02
0.237CysGln: 0.237 ± 0.014
0.305CysArg: 0.305 ± 0.017
0.461CysSer: 0.461 ± 0.021
0.428CysThr: 0.428 ± 0.017
0.416CysVal: 0.416 ± 0.019
0.082CysTrp: 0.082 ± 0.008
0.294CysTyr: 0.294 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
3.677AspAla: 3.677 ± 0.058
0.388AspCys: 0.388 ± 0.021
2.307AspAsp: 2.307 ± 0.052
4.524AspGlu: 4.524 ± 0.065
2.494AspPhe: 2.494 ± 0.045
3.399AspGly: 3.399 ± 0.061
1.005AspHis: 1.005 ± 0.029
4.229AspIle: 4.229 ± 0.065
2.75AspLys: 2.75 ± 0.056
4.571AspLeu: 4.571 ± 0.068
1.38AspMet: 1.38 ± 0.035
1.651AspAsn: 1.651 ± 0.042
1.739AspPro: 1.739 ± 0.041
1.665AspGln: 1.665 ± 0.039
2.079AspArg: 2.079 ± 0.043
2.36AspSer: 2.36 ± 0.051
2.563AspThr: 2.563 ± 0.057
3.752AspVal: 3.752 ± 0.052
0.603AspTrp: 0.603 ± 0.021
2.332AspTyr: 2.332 ± 0.046
0.0AspXaa: 0.0 ± 0.0
Glu
6.201GluAla: 6.201 ± 0.077
0.403GluCys: 0.403 ± 0.02
3.778GluAsp: 3.778 ± 0.062
7.911GluGlu: 7.911 ± 0.112
2.56GluPhe: 2.56 ± 0.045
4.542GluGly: 4.542 ± 0.071
1.642GluHis: 1.642 ± 0.039
5.597GluIle: 5.597 ± 0.076
6.378GluLys: 6.378 ± 0.08
7.479GluLeu: 7.479 ± 0.091
2.529GluMet: 2.529 ± 0.046
3.497GluAsn: 3.497 ± 0.067
1.99GluPro: 1.99 ± 0.042
4.054GluGln: 4.054 ± 0.07
3.749GluArg: 3.749 ± 0.053
3.339GluSer: 3.339 ± 0.057
3.91GluThr: 3.91 ± 0.048
5.311GluVal: 5.311 ± 0.068
0.846GluTrp: 0.846 ± 0.031
2.384GluTyr: 2.384 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
3.264PheAla: 3.264 ± 0.052
0.382PheCys: 0.382 ± 0.019
2.384PheAsp: 2.384 ± 0.05
3.17PheGlu: 3.17 ± 0.06
2.339PhePhe: 2.339 ± 0.061
3.213PheGly: 3.213 ± 0.065
1.004PheHis: 1.004 ± 0.029
4.052PheIle: 4.052 ± 0.078
2.319PheLys: 2.319 ± 0.043
4.378PheLeu: 4.378 ± 0.085
1.268PheMet: 1.268 ± 0.031
1.836PheAsn: 1.836 ± 0.046
1.539PhePro: 1.539 ± 0.041
1.484PheGln: 1.484 ± 0.041
1.535PheArg: 1.535 ± 0.034
3.102PheSer: 3.102 ± 0.062
2.917PheThr: 2.917 ± 0.049
3.152PheVal: 3.152 ± 0.056
0.481PheTrp: 0.481 ± 0.022
1.834PheTyr: 1.834 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
5.003GlyAla: 5.003 ± 0.085
0.609GlyCys: 0.609 ± 0.023
3.23GlyAsp: 3.23 ± 0.053
4.706GlyGlu: 4.706 ± 0.075
3.281GlyPhe: 3.281 ± 0.06
4.706GlyGly: 4.706 ± 0.093
1.384GlyHis: 1.384 ± 0.038
5.7GlyIle: 5.7 ± 0.077
4.69GlyLys: 4.69 ± 0.067
6.34GlyLeu: 6.34 ± 0.088
2.108GlyMet: 2.108 ± 0.046
2.552GlyAsn: 2.552 ± 0.056
1.586GlyPro: 1.586 ± 0.041
2.285GlyGln: 2.285 ± 0.052
2.727GlyArg: 2.727 ± 0.052
3.784GlySer: 3.784 ± 0.056
4.057GlyThr: 4.057 ± 0.067
4.837GlyVal: 4.837 ± 0.068
0.742GlyTrp: 0.742 ± 0.028
2.778GlyTyr: 2.778 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
1.447HisAla: 1.447 ± 0.036
0.206HisCys: 0.206 ± 0.016
0.952HisAsp: 0.952 ± 0.028
1.504HisGlu: 1.504 ± 0.042
1.113HisPhe: 1.113 ± 0.03
1.325HisGly: 1.325 ± 0.032
0.642HisHis: 0.642 ± 0.027
1.749HisIle: 1.749 ± 0.04
1.021HisLys: 1.021 ± 0.028
2.119HisLeu: 2.119 ± 0.043
0.576HisMet: 0.576 ± 0.025
0.745HisAsn: 0.745 ± 0.028
1.035HisPro: 1.035 ± 0.033
0.814HisGln: 0.814 ± 0.031
0.778HisArg: 0.778 ± 0.026
1.096HisSer: 1.096 ± 0.033
1.084HisThr: 1.084 ± 0.029
1.407HisVal: 1.407 ± 0.038
0.2HisTrp: 0.2 ± 0.013
0.993HisTyr: 0.993 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
6.479IleAla: 6.479 ± 0.077
0.689IleCys: 0.689 ± 0.023
4.356IleAsp: 4.356 ± 0.066
6.166IleGlu: 6.166 ± 0.07
3.291IlePhe: 3.291 ± 0.061
5.989IleGly: 5.989 ± 0.087
1.62IleHis: 1.62 ± 0.034
5.958IleIle: 5.958 ± 0.086
4.074IleLys: 4.074 ± 0.061
7.1IleLeu: 7.1 ± 0.091
1.874IleMet: 1.874 ± 0.042
3.014IleAsn: 3.014 ± 0.051
3.186IlePro: 3.186 ± 0.047
3.027IleGln: 3.027 ± 0.058
3.139IleArg: 3.139 ± 0.055
4.77IleSer: 4.77 ± 0.062
4.355IleThr: 4.355 ± 0.057
5.765IleVal: 5.765 ± 0.067
0.67IleTrp: 0.67 ± 0.031
2.565IleTyr: 2.565 ± 0.054
0.0IleXaa: 0.0 ± 0.0
Lys
4.726LysAla: 4.726 ± 0.064
0.346LysCys: 0.346 ± 0.018
3.316LysAsp: 3.316 ± 0.06
6.507LysGlu: 6.507 ± 0.076
1.964LysPhe: 1.964 ± 0.04
4.114LysGly: 4.114 ± 0.062
1.208LysHis: 1.208 ± 0.033
4.249LysIle: 4.249 ± 0.06
5.186LysLys: 5.186 ± 0.077
5.687LysLeu: 5.687 ± 0.071
2.264LysMet: 2.264 ± 0.037
2.992LysAsn: 2.992 ± 0.058
2.178LysPro: 2.178 ± 0.049
3.003LysGln: 3.003 ± 0.05
3.165LysArg: 3.165 ± 0.053
3.215LysSer: 3.215 ± 0.05
3.409LysThr: 3.409 ± 0.053
4.283LysVal: 4.283 ± 0.069
0.802LysTrp: 0.802 ± 0.029
2.153LysTyr: 2.153 ± 0.047
0.0LysXaa: 0.0 ± 0.0
Leu
8.199LeuAla: 8.199 ± 0.093
0.693LeuCys: 0.693 ± 0.026
4.585LeuAsp: 4.585 ± 0.064
6.815LeuGlu: 6.815 ± 0.087
4.86LeuPhe: 4.86 ± 0.083
6.062LeuGly: 6.062 ± 0.076
2.142LeuHis: 2.142 ± 0.045
6.95LeuIle: 6.95 ± 0.093
6.083LeuLys: 6.083 ± 0.07
10.667LeuLeu: 10.667 ± 0.144
2.577LeuMet: 2.577 ± 0.046
3.852LeuAsn: 3.852 ± 0.062
4.039LeuPro: 4.039 ± 0.068
4.153LeuGln: 4.153 ± 0.065
3.63LeuArg: 3.63 ± 0.053
6.292LeuSer: 6.292 ± 0.084
5.792LeuThr: 5.792 ± 0.075
6.358LeuVal: 6.358 ± 0.083
0.806LeuTrp: 0.806 ± 0.031
3.481LeuTyr: 3.481 ± 0.066
0.0LeuXaa: 0.0 ± 0.0
Met
2.189MetAla: 2.189 ± 0.053
0.154MetCys: 0.154 ± 0.013
1.494MetAsp: 1.494 ± 0.032
2.162MetGlu: 2.162 ± 0.048
1.099MetPhe: 1.099 ± 0.033
1.706MetGly: 1.706 ± 0.043
0.523MetHis: 0.523 ± 0.02
2.086MetIle: 2.086 ± 0.046
2.584MetLys: 2.584 ± 0.047
2.848MetLeu: 2.848 ± 0.047
0.926MetMet: 0.926 ± 0.028
1.5MetAsn: 1.5 ± 0.034
1.13MetPro: 1.13 ± 0.03
1.145MetGln: 1.145 ± 0.035
1.186MetArg: 1.186 ± 0.028
1.642MetSer: 1.642 ± 0.042
1.874MetThr: 1.874 ± 0.04
1.632MetVal: 1.632 ± 0.038
0.189MetTrp: 0.189 ± 0.013
0.849MetTyr: 0.849 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
2.955AsnAla: 2.955 ± 0.06
0.288AsnCys: 0.288 ± 0.017
2.021AsnAsp: 2.021 ± 0.047
3.492AsnGlu: 3.492 ± 0.057
1.607AsnPhe: 1.607 ± 0.036
3.163AsnGly: 3.163 ± 0.061
0.838AsnHis: 0.838 ± 0.027
3.355AsnIle: 3.355 ± 0.058
2.615AsnLys: 2.615 ± 0.052
3.496AsnLeu: 3.496 ± 0.063
1.158AsnMet: 1.158 ± 0.032
1.852AsnAsn: 1.852 ± 0.051
1.912AsnPro: 1.912 ± 0.043
1.429AsnGln: 1.429 ± 0.034
1.886AsnArg: 1.886 ± 0.048
2.065AsnSer: 2.065 ± 0.04
2.155AsnThr: 2.155 ± 0.046
2.802AsnVal: 2.802 ± 0.046
0.455AsnTrp: 0.455 ± 0.022
1.5AsnTyr: 1.5 ± 0.036
0.0AsnXaa: 0.0 ± 0.0
Pro
2.68ProAla: 2.68 ± 0.051
0.216ProCys: 0.216 ± 0.015
1.839ProAsp: 1.839 ± 0.044
2.779ProGlu: 2.779 ± 0.053
1.996ProPhe: 1.996 ± 0.043
2.148ProGly: 2.148 ± 0.049
0.846ProHis: 0.846 ± 0.027
2.728ProIle: 2.728 ± 0.05
2.001ProLys: 2.001 ± 0.046
3.435ProLeu: 3.435 ± 0.063
0.864ProMet: 0.864 ± 0.024
1.511ProAsn: 1.511 ± 0.038
1.022ProPro: 1.022 ± 0.04
1.237ProGln: 1.237 ± 0.038
1.041ProArg: 1.041 ± 0.033
2.171ProSer: 2.171 ± 0.045
1.929ProThr: 1.929 ± 0.044
2.884ProVal: 2.884 ± 0.053
0.344ProTrp: 0.344 ± 0.018
1.421ProTyr: 1.421 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
3.145GlnAla: 3.145 ± 0.058
0.229GlnCys: 0.229 ± 0.015
1.616GlnAsp: 1.616 ± 0.038
2.842GlnGlu: 2.842 ± 0.053
1.712GlnPhe: 1.712 ± 0.037
2.165GlnGly: 2.165 ± 0.044
0.862GlnHis: 0.862 ± 0.031
2.774GlnIle: 2.774 ± 0.052
2.631GlnLys: 2.631 ± 0.052
4.45GlnLeu: 4.45 ± 0.064
1.222GlnMet: 1.222 ± 0.033
1.501GlnAsn: 1.501 ± 0.035
1.257GlnPro: 1.257 ± 0.039
2.124GlnGln: 2.124 ± 0.048
1.53GlnArg: 1.53 ± 0.037
2.021GlnSer: 2.021 ± 0.047
2.114GlnThr: 2.114 ± 0.047
2.503GlnVal: 2.503 ± 0.049
0.389GlnTrp: 0.389 ± 0.019
1.466GlnTyr: 1.466 ± 0.038
0.0GlnXaa: 0.0 ± 0.0
Arg
2.729ArgAla: 2.729 ± 0.052
0.249ArgCys: 0.249 ± 0.015
1.998ArgAsp: 1.998 ± 0.051
3.333ArgGlu: 3.333 ± 0.058
1.943ArgPhe: 1.943 ± 0.041
2.346ArgGly: 2.346 ± 0.05
0.9ArgHis: 0.9 ± 0.029
3.075ArgIle: 3.075 ± 0.054
2.963ArgLys: 2.963 ± 0.054
4.201ArgLeu: 4.201 ± 0.065
1.268ArgMet: 1.268 ± 0.032
1.794ArgAsn: 1.794 ± 0.038
1.305ArgPro: 1.305 ± 0.033
1.688ArgGln: 1.688 ± 0.038
1.761ArgArg: 1.761 ± 0.045
2.069ArgSer: 2.069 ± 0.044
2.135ArgThr: 2.135 ± 0.042
2.595ArgVal: 2.595 ± 0.045
0.394ArgTrp: 0.394 ± 0.019
1.658ArgTyr: 1.658 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
3.929SerAla: 3.929 ± 0.065
0.373SerCys: 0.373 ± 0.017
2.642SerAsp: 2.642 ± 0.058
3.548SerGlu: 3.548 ± 0.06
3.202SerPhe: 3.202 ± 0.058
3.919SerGly: 3.919 ± 0.062
1.149SerHis: 1.149 ± 0.03
4.825SerIle: 4.825 ± 0.074
3.392SerLys: 3.392 ± 0.054
5.874SerLeu: 5.874 ± 0.071
1.713SerMet: 1.713 ± 0.036
2.298SerAsn: 2.298 ± 0.044
2.056SerPro: 2.056 ± 0.047
1.794SerGln: 1.794 ± 0.041
2.177SerArg: 2.177 ± 0.045
3.67SerSer: 3.67 ± 0.058
3.093SerThr: 3.093 ± 0.053
3.832SerVal: 3.832 ± 0.058
0.602SerTrp: 0.602 ± 0.023
2.323SerTyr: 2.323 ± 0.045
0.0SerXaa: 0.0 ± 0.0
Thr
4.691ThrAla: 4.691 ± 0.07
0.339ThrCys: 0.339 ± 0.015
2.748ThrAsp: 2.748 ± 0.054
3.92ThrGlu: 3.92 ± 0.066
2.676ThrPhe: 2.676 ± 0.053
4.152ThrGly: 4.152 ± 0.074
1.048ThrHis: 1.048 ± 0.03
4.653ThrIle: 4.653 ± 0.062
3.298ThrLys: 3.298 ± 0.048
5.186ThrLeu: 5.186 ± 0.075
1.416ThrMet: 1.416 ± 0.036
2.361ThrAsn: 2.361 ± 0.046
2.226ThrPro: 2.226 ± 0.045
1.6ThrGln: 1.6 ± 0.039
1.895ThrArg: 1.895 ± 0.042
3.195ThrSer: 3.195 ± 0.052
3.13ThrThr: 3.13 ± 0.066
4.456ThrVal: 4.456 ± 0.066
0.494ThrTrp: 0.494 ± 0.021
2.148ThrTyr: 2.148 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
5.319ValAla: 5.319 ± 0.087
0.603ValCys: 0.603 ± 0.024
3.58ValAsp: 3.58 ± 0.059
5.136ValGlu: 5.136 ± 0.069
3.097ValPhe: 3.097 ± 0.053
4.591ValGly: 4.591 ± 0.081
1.409ValHis: 1.409 ± 0.035
5.387ValIle: 5.387 ± 0.074
4.653ValLys: 4.653 ± 0.06
7.076ValLeu: 7.076 ± 0.079
2.015ValMet: 2.015 ± 0.044
2.87ValAsn: 2.87 ± 0.057
2.687ValPro: 2.687 ± 0.053
2.497ValGln: 2.497 ± 0.044
2.77ValArg: 2.77 ± 0.051
4.16ValSer: 4.16 ± 0.069
4.27ValThr: 4.27 ± 0.071
5.023ValVal: 5.023 ± 0.086
0.603ValTrp: 0.603 ± 0.023
2.367ValTyr: 2.367 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.638TrpAla: 0.638 ± 0.025
0.092TrpCys: 0.092 ± 0.009
0.465TrpAsp: 0.465 ± 0.022
0.643TrpGlu: 0.643 ± 0.023
0.487TrpPhe: 0.487 ± 0.024
0.651TrpGly: 0.651 ± 0.026
0.225TrpHis: 0.225 ± 0.014
0.777TrpIle: 0.777 ± 0.026
0.632TrpLys: 0.632 ± 0.026
1.103TrpLeu: 1.103 ± 0.032
0.362TrpMet: 0.362 ± 0.019
0.468TrpAsn: 0.468 ± 0.023
0.255TrpPro: 0.255 ± 0.017
0.423TrpGln: 0.423 ± 0.02
0.433TrpArg: 0.433 ± 0.021
0.579TrpSer: 0.579 ± 0.021
0.537TrpThr: 0.537 ± 0.023
0.622TrpVal: 0.622 ± 0.02
0.123TrpTrp: 0.123 ± 0.011
0.347TrpTyr: 0.347 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.522TyrAla: 2.522 ± 0.046
0.305TyrCys: 0.305 ± 0.017
1.99TyrAsp: 1.99 ± 0.041
3.038TyrGlu: 3.038 ± 0.061
1.97TyrPhe: 1.97 ± 0.048
2.53TyrGly: 2.53 ± 0.048
0.763TyrHis: 0.763 ± 0.025
2.825TyrIle: 2.825 ± 0.045
2.239TyrLys: 2.239 ± 0.05
3.493TyrLeu: 3.493 ± 0.065
0.963TyrMet: 0.963 ± 0.032
1.585TyrAsn: 1.585 ± 0.037
1.39TyrPro: 1.39 ± 0.037
1.275TyrGln: 1.275 ± 0.034
1.65TyrArg: 1.65 ± 0.041
2.184TyrSer: 2.184 ± 0.047
2.132TyrThr: 2.132 ± 0.045
2.313TyrVal: 2.313 ± 0.048
0.374TyrTrp: 0.374 ± 0.019
1.545TyrTyr: 1.545 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4109 proteins (1154994 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski