Amino acid dipepetide frequency for Prevotella oryzae DSM 17970

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.976AlaAla: 3.976 ± 0.263
0.855AlaCys: 0.855 ± 0.085
4.165AlaAsp: 4.165 ± 0.246
3.449AlaGlu: 3.449 ± 0.219
2.813AlaPhe: 2.813 ± 0.17
4.125AlaGly: 4.125 ± 0.219
1.103AlaHis: 1.103 ± 0.097
4.87AlaIle: 4.87 ± 0.263
4.433AlaLys: 4.433 ± 0.242
5.526AlaLeu: 5.526 ± 0.278
1.829AlaMet: 1.829 ± 0.125
3.369AlaAsn: 3.369 ± 0.222
1.62AlaPro: 1.62 ± 0.13
2.306AlaGln: 2.306 ± 0.167
2.306AlaArg: 2.306 ± 0.142
4.264AlaSer: 4.264 ± 0.2
3.787AlaThr: 3.787 ± 0.201
3.618AlaVal: 3.618 ± 0.235
0.885AlaTrp: 0.885 ± 0.108
2.704AlaTyr: 2.704 ± 0.167
0.0AlaXaa: 0.0 ± 0.0
Cys
0.686CysAla: 0.686 ± 0.067
0.288CysCys: 0.288 ± 0.053
0.805CysAsp: 0.805 ± 0.087
0.606CysGlu: 0.606 ± 0.078
0.596CysPhe: 0.596 ± 0.085
1.064CysGly: 1.064 ± 0.107
0.258CysHis: 0.258 ± 0.053
0.974CysIle: 0.974 ± 0.1
0.835CysLys: 0.835 ± 0.088
1.054CysLeu: 1.054 ± 0.107
0.328CysMet: 0.328 ± 0.052
0.895CysAsn: 0.895 ± 0.092
0.467CysPro: 0.467 ± 0.069
0.278CysGln: 0.278 ± 0.043
0.567CysArg: 0.567 ± 0.092
1.004CysSer: 1.004 ± 0.102
0.576CysThr: 0.576 ± 0.079
0.686CysVal: 0.686 ± 0.08
0.099CysTrp: 0.099 ± 0.032
0.616CysTyr: 0.616 ± 0.08
0.0CysXaa: 0.0 ± 0.0
Asp
4.145AspAla: 4.145 ± 0.248
0.666AspCys: 0.666 ± 0.084
3.32AspAsp: 3.32 ± 0.207
3.707AspGlu: 3.707 ± 0.198
3.191AspPhe: 3.191 ± 0.193
4.622AspGly: 4.622 ± 0.275
0.795AspHis: 0.795 ± 0.105
4.821AspIle: 4.821 ± 0.23
4.513AspLys: 4.513 ± 0.22
4.801AspLeu: 4.801 ± 0.212
1.729AspMet: 1.729 ± 0.113
3.976AspAsn: 3.976 ± 0.215
2.008AspPro: 2.008 ± 0.184
1.521AspGln: 1.521 ± 0.143
2.097AspArg: 2.097 ± 0.156
3.866AspSer: 3.866 ± 0.224
2.624AspThr: 2.624 ± 0.16
3.648AspVal: 3.648 ± 0.181
1.034AspTrp: 1.034 ± 0.088
2.902AspTyr: 2.902 ± 0.173
0.0AspXaa: 0.0 ± 0.0
Glu
3.26GluAla: 3.26 ± 0.243
0.567GluCys: 0.567 ± 0.079
3.141GluAsp: 3.141 ± 0.203
3.489GluGlu: 3.489 ± 0.268
2.117GluPhe: 2.117 ± 0.13
3.3GluGly: 3.3 ± 0.193
1.143GluHis: 1.143 ± 0.113
4.294GluIle: 4.294 ± 0.312
4.224GluLys: 4.224 ± 0.239
4.294GluLeu: 4.294 ± 0.215
1.839GluMet: 1.839 ± 0.145
3.28GluAsn: 3.28 ± 0.211
1.56GluPro: 1.56 ± 0.131
1.67GluGln: 1.67 ± 0.12
2.664GluArg: 2.664 ± 0.158
2.902GluSer: 2.902 ± 0.17
2.614GluThr: 2.614 ± 0.179
3.051GluVal: 3.051 ± 0.202
0.745GluTrp: 0.745 ± 0.081
2.187GluTyr: 2.187 ± 0.15
0.0GluXaa: 0.0 ± 0.0
Phe
2.833PheAla: 2.833 ± 0.182
0.795PheCys: 0.795 ± 0.093
2.972PheAsp: 2.972 ± 0.15
2.465PheGlu: 2.465 ± 0.173
2.276PhePhe: 2.276 ± 0.162
3.618PheGly: 3.618 ± 0.241
0.745PheHis: 0.745 ± 0.089
3.618PheIle: 3.618 ± 0.251
3.23PheLys: 3.23 ± 0.21
3.32PheLeu: 3.32 ± 0.206
1.531PheMet: 1.531 ± 0.142
2.992PheAsn: 2.992 ± 0.188
1.541PhePro: 1.541 ± 0.128
1.133PheGln: 1.133 ± 0.117
1.72PheArg: 1.72 ± 0.142
3.876PheSer: 3.876 ± 0.182
2.614PheThr: 2.614 ± 0.16
2.415PheVal: 2.415 ± 0.18
0.696PheTrp: 0.696 ± 0.105
2.018PheTyr: 2.018 ± 0.142
0.0PheXaa: 0.0 ± 0.0
Gly
3.976GlyAla: 3.976 ± 0.269
0.845GlyCys: 0.845 ± 0.075
3.578GlyAsp: 3.578 ± 0.193
3.101GlyGlu: 3.101 ± 0.172
3.041GlyPhe: 3.041 ± 0.178
5.0GlyGly: 5.0 ± 0.359
1.362GlyHis: 1.362 ± 0.114
5.447GlyIle: 5.447 ± 0.262
5.407GlyLys: 5.407 ± 0.286
5.487GlyLeu: 5.487 ± 0.262
2.157GlyMet: 2.157 ± 0.156
4.393GlyAsn: 4.393 ± 0.253
1.342GlyPro: 1.342 ± 0.135
2.067GlyGln: 2.067 ± 0.153
2.356GlyArg: 2.356 ± 0.158
4.751GlySer: 4.751 ± 0.259
4.214GlyThr: 4.214 ± 0.267
4.691GlyVal: 4.691 ± 0.266
1.292GlyTrp: 1.292 ± 0.143
3.588GlyTyr: 3.588 ± 0.237
0.0GlyXaa: 0.0 ± 0.0
His
0.924HisAla: 0.924 ± 0.107
0.248HisCys: 0.248 ± 0.054
1.034HisAsp: 1.034 ± 0.122
0.934HisGlu: 0.934 ± 0.1
1.093HisPhe: 1.093 ± 0.099
1.431HisGly: 1.431 ± 0.116
0.557HisHis: 0.557 ± 0.076
1.57HisIle: 1.57 ± 0.134
1.252HisLys: 1.252 ± 0.137
1.739HisLeu: 1.739 ± 0.128
0.427HisMet: 0.427 ± 0.073
1.372HisAsn: 1.372 ± 0.118
0.845HisPro: 0.845 ± 0.088
0.716HisGln: 0.716 ± 0.082
0.855HisArg: 0.855 ± 0.093
1.322HisSer: 1.322 ± 0.135
1.004HisThr: 1.004 ± 0.107
1.064HisVal: 1.064 ± 0.1
0.159HisTrp: 0.159 ± 0.037
1.034HisTyr: 1.034 ± 0.103
0.0HisXaa: 0.0 ± 0.0
Ile
5.079IleAla: 5.079 ± 0.276
1.014IleCys: 1.014 ± 0.122
4.731IleAsp: 4.731 ± 0.207
4.403IleGlu: 4.403 ± 0.261
3.36IlePhe: 3.36 ± 0.207
5.576IleGly: 5.576 ± 0.246
1.382IleHis: 1.382 ± 0.143
6.312IleIle: 6.312 ± 0.376
5.854IleLys: 5.854 ± 0.308
6.62IleLeu: 6.62 ± 0.337
1.739IleMet: 1.739 ± 0.147
4.97IleAsn: 4.97 ± 0.223
3.191IlePro: 3.191 ± 0.209
2.217IleGln: 2.217 ± 0.148
3.419IleArg: 3.419 ± 0.207
6.013IleSer: 6.013 ± 0.252
4.761IleThr: 4.761 ± 0.204
4.731IleVal: 4.731 ± 0.279
0.984IleTrp: 0.984 ± 0.135
3.26IleTyr: 3.26 ± 0.149
0.0IleXaa: 0.0 ± 0.0
Lys
4.572LysAla: 4.572 ± 0.219
0.726LysCys: 0.726 ± 0.089
5.119LysAsp: 5.119 ± 0.246
4.721LysGlu: 4.721 ± 0.265
2.674LysPhe: 2.674 ± 0.161
4.841LysGly: 4.841 ± 0.241
1.352LysHis: 1.352 ± 0.127
5.795LysIle: 5.795 ± 0.285
5.407LysLys: 5.407 ± 0.271
5.387LysLeu: 5.387 ± 0.242
2.326LysMet: 2.326 ± 0.148
4.99LysAsn: 4.99 ± 0.236
1.859LysPro: 1.859 ± 0.12
2.554LysGln: 2.554 ± 0.141
3.181LysArg: 3.181 ± 0.2
4.254LysSer: 4.254 ± 0.247
4.016LysThr: 4.016 ± 0.192
3.916LysVal: 3.916 ± 0.21
1.123LysTrp: 1.123 ± 0.12
3.519LysTyr: 3.519 ± 0.19
0.0LysXaa: 0.0 ± 0.0
Leu
5.109LeuAla: 5.109 ± 0.276
1.113LeuCys: 1.113 ± 0.111
4.642LeuAsp: 4.642 ± 0.229
3.419LeuGlu: 3.419 ± 0.218
4.304LeuPhe: 4.304 ± 0.287
5.009LeuGly: 5.009 ± 0.267
1.799LeuHis: 1.799 ± 0.164
6.083LeuIle: 6.083 ± 0.286
6.252LeuLys: 6.252 ± 0.242
7.634LeuLeu: 7.634 ± 0.348
2.366LeuMet: 2.366 ± 0.163
5.188LeuAsn: 5.188 ± 0.203
3.399LeuPro: 3.399 ± 0.219
2.475LeuGln: 2.475 ± 0.151
3.628LeuArg: 3.628 ± 0.2
6.968LeuSer: 6.968 ± 0.278
4.761LeuThr: 4.761 ± 0.234
4.602LeuVal: 4.602 ± 0.249
1.203LeuTrp: 1.203 ± 0.131
3.36LeuTyr: 3.36 ± 0.203
0.0LeuXaa: 0.0 ± 0.0
Met
1.759MetAla: 1.759 ± 0.148
0.388MetCys: 0.388 ± 0.065
1.68MetAsp: 1.68 ± 0.114
1.292MetGlu: 1.292 ± 0.119
1.004MetPhe: 1.004 ± 0.095
1.729MetGly: 1.729 ± 0.137
0.706MetHis: 0.706 ± 0.077
1.958MetIle: 1.958 ± 0.178
2.654MetLys: 2.654 ± 0.154
2.694MetLeu: 2.694 ± 0.164
1.004MetMet: 1.004 ± 0.129
1.68MetAsn: 1.68 ± 0.133
1.242MetPro: 1.242 ± 0.122
1.143MetGln: 1.143 ± 0.106
1.302MetArg: 1.302 ± 0.112
1.998MetSer: 1.998 ± 0.14
1.421MetThr: 1.421 ± 0.114
1.511MetVal: 1.511 ± 0.132
0.308MetTrp: 0.308 ± 0.062
1.173MetTyr: 1.173 ± 0.108
0.0MetXaa: 0.0 ± 0.0
Asn
3.658AsnAla: 3.658 ± 0.201
0.716AsnCys: 0.716 ± 0.093
3.558AsnAsp: 3.558 ± 0.201
3.111AsnGlu: 3.111 ± 0.227
2.912AsnPhe: 2.912 ± 0.163
4.92AsnGly: 4.92 ± 0.285
1.411AsnHis: 1.411 ± 0.123
5.874AsnIle: 5.874 ± 0.328
4.681AsnLys: 4.681 ± 0.221
5.089AsnLeu: 5.089 ± 0.239
1.759AsnMet: 1.759 ± 0.151
4.175AsnAsn: 4.175 ± 0.276
2.604AsnPro: 2.604 ± 0.158
1.63AsnGln: 1.63 ± 0.126
2.266AsnArg: 2.266 ± 0.143
4.185AsnSer: 4.185 ± 0.286
3.379AsnThr: 3.379 ± 0.189
3.936AsnVal: 3.936 ± 0.252
0.805AsnTrp: 0.805 ± 0.1
2.972AsnTyr: 2.972 ± 0.215
0.0AsnXaa: 0.0 ± 0.0
Pro
1.978ProAla: 1.978 ± 0.14
0.308ProCys: 0.308 ± 0.064
2.296ProAsp: 2.296 ± 0.151
2.356ProGlu: 2.356 ± 0.159
1.65ProPhe: 1.65 ± 0.133
1.968ProGly: 1.968 ± 0.149
0.686ProHis: 0.686 ± 0.092
2.594ProIle: 2.594 ± 0.144
2.107ProLys: 2.107 ± 0.181
3.002ProLeu: 3.002 ± 0.208
0.795ProMet: 0.795 ± 0.107
1.958ProAsn: 1.958 ± 0.144
0.557ProPro: 0.557 ± 0.077
1.302ProGln: 1.302 ± 0.121
1.073ProArg: 1.073 ± 0.089
2.554ProSer: 2.554 ± 0.182
1.888ProThr: 1.888 ± 0.149
2.048ProVal: 2.048 ± 0.157
0.527ProTrp: 0.527 ± 0.086
1.888ProTyr: 1.888 ± 0.176
0.0ProXaa: 0.0 ± 0.0
Gln
2.028GlnAla: 2.028 ± 0.153
0.437GlnCys: 0.437 ± 0.073
1.481GlnAsp: 1.481 ± 0.124
1.491GlnGlu: 1.491 ± 0.129
1.352GlnPhe: 1.352 ± 0.115
1.859GlnGly: 1.859 ± 0.161
0.586GlnHis: 0.586 ± 0.069
2.584GlnIle: 2.584 ± 0.174
2.405GlnLys: 2.405 ± 0.168
2.873GlnLeu: 2.873 ± 0.186
1.024GlnMet: 1.024 ± 0.114
1.988GlnAsn: 1.988 ± 0.141
1.163GlnPro: 1.163 ± 0.103
1.491GlnGln: 1.491 ± 0.136
1.441GlnArg: 1.441 ± 0.121
1.819GlnSer: 1.819 ± 0.151
1.948GlnThr: 1.948 ± 0.135
1.978GlnVal: 1.978 ± 0.149
0.666GlnTrp: 0.666 ± 0.084
1.302GlnTyr: 1.302 ± 0.112
0.0GlnXaa: 0.0 ± 0.0
Arg
2.495ArgAla: 2.495 ± 0.184
0.417ArgCys: 0.417 ± 0.06
2.217ArgAsp: 2.217 ± 0.146
1.938ArgGlu: 1.938 ± 0.183
2.157ArgPhe: 2.157 ± 0.137
2.067ArgGly: 2.067 ± 0.143
0.855ArgHis: 0.855 ± 0.089
3.29ArgIle: 3.29 ± 0.214
2.882ArgLys: 2.882 ± 0.16
3.697ArgLeu: 3.697 ± 0.172
1.352ArgMet: 1.352 ± 0.128
2.485ArgAsn: 2.485 ± 0.176
1.282ArgPro: 1.282 ± 0.11
1.6ArgGln: 1.6 ± 0.136
2.018ArgArg: 2.018 ± 0.199
2.127ArgSer: 2.127 ± 0.142
2.187ArgThr: 2.187 ± 0.15
2.147ArgVal: 2.147 ± 0.151
0.616ArgTrp: 0.616 ± 0.076
2.048ArgTyr: 2.048 ± 0.151
0.0ArgXaa: 0.0 ± 0.0
Ser
4.284SerAla: 4.284 ± 0.235
0.924SerCys: 0.924 ± 0.093
4.145SerAsp: 4.145 ± 0.231
3.399SerGlu: 3.399 ± 0.195
3.578SerPhe: 3.578 ± 0.197
4.88SerGly: 4.88 ± 0.223
1.382SerHis: 1.382 ± 0.123
5.656SerIle: 5.656 ± 0.248
4.552SerLys: 4.552 ± 0.232
5.854SerLeu: 5.854 ± 0.278
1.7SerMet: 1.7 ± 0.115
3.936SerAsn: 3.936 ± 0.247
2.385SerPro: 2.385 ± 0.163
2.077SerGln: 2.077 ± 0.136
2.485SerArg: 2.485 ± 0.166
5.059SerSer: 5.059 ± 0.322
3.936SerThr: 3.936 ± 0.223
4.552SerVal: 4.552 ± 0.239
1.044SerTrp: 1.044 ± 0.097
3.678SerTyr: 3.678 ± 0.233
0.0SerXaa: 0.0 ± 0.0
Thr
3.767ThrAla: 3.767 ± 0.209
0.626ThrCys: 0.626 ± 0.093
3.568ThrAsp: 3.568 ± 0.192
2.713ThrGlu: 2.713 ± 0.164
2.902ThrPhe: 2.902 ± 0.19
4.085ThrGly: 4.085 ± 0.194
1.054ThrHis: 1.054 ± 0.111
4.761ThrIle: 4.761 ± 0.207
3.31ThrLys: 3.31 ± 0.186
4.88ThrLeu: 4.88 ± 0.246
1.511ThrMet: 1.511 ± 0.119
3.28ThrAsn: 3.28 ± 0.197
2.296ThrPro: 2.296 ± 0.156
1.69ThrGln: 1.69 ± 0.138
1.59ThrArg: 1.59 ± 0.122
3.688ThrSer: 3.688 ± 0.182
3.509ThrThr: 3.509 ± 0.243
3.707ThrVal: 3.707 ± 0.204
0.686ThrTrp: 0.686 ± 0.093
2.564ThrTyr: 2.564 ± 0.196
0.0ThrXaa: 0.0 ± 0.0
Val
3.787ValAla: 3.787 ± 0.251
0.865ValCys: 0.865 ± 0.088
3.847ValAsp: 3.847 ± 0.189
3.171ValGlu: 3.171 ± 0.163
2.723ValPhe: 2.723 ± 0.183
3.509ValGly: 3.509 ± 0.224
1.312ValHis: 1.312 ± 0.127
4.383ValIle: 4.383 ± 0.23
4.314ValLys: 4.314 ± 0.223
4.801ValLeu: 4.801 ± 0.241
1.57ValMet: 1.57 ± 0.124
4.045ValAsn: 4.045 ± 0.209
2.336ValPro: 2.336 ± 0.172
1.67ValGln: 1.67 ± 0.121
2.346ValArg: 2.346 ± 0.159
4.214ValSer: 4.214 ± 0.213
3.558ValThr: 3.558 ± 0.251
3.827ValVal: 3.827 ± 0.22
0.636ValTrp: 0.636 ± 0.076
2.495ValTyr: 2.495 ± 0.159
0.0ValXaa: 0.0 ± 0.0
Trp
0.934TrpAla: 0.934 ± 0.085
0.179TrpCys: 0.179 ± 0.042
0.686TrpAsp: 0.686 ± 0.087
0.636TrpGlu: 0.636 ± 0.084
0.775TrpPhe: 0.775 ± 0.094
1.143TrpGly: 1.143 ± 0.12
0.239TrpHis: 0.239 ± 0.052
1.213TrpIle: 1.213 ± 0.13
0.954TrpLys: 0.954 ± 0.099
0.934TrpLeu: 0.934 ± 0.097
0.467TrpMet: 0.467 ± 0.073
1.133TrpAsn: 1.133 ± 0.112
0.288TrpPro: 0.288 ± 0.062
0.726TrpGln: 0.726 ± 0.1
0.696TrpArg: 0.696 ± 0.094
1.123TrpSer: 1.123 ± 0.116
0.755TrpThr: 0.755 ± 0.089
0.636TrpVal: 0.636 ± 0.073
0.318TrpTrp: 0.318 ± 0.058
0.726TrpTyr: 0.726 ± 0.078
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.753TyrAla: 2.753 ± 0.175
0.706TyrCys: 0.706 ± 0.074
3.002TyrAsp: 3.002 ± 0.181
1.948TyrGlu: 1.948 ± 0.151
1.888TyrPhe: 1.888 ± 0.143
3.35TyrGly: 3.35 ± 0.226
0.855TyrHis: 0.855 ± 0.108
3.519TyrIle: 3.519 ± 0.183
3.061TyrLys: 3.061 ± 0.164
3.628TyrLeu: 3.628 ± 0.193
1.183TyrMet: 1.183 ± 0.115
3.538TyrAsn: 3.538 ± 0.225
1.551TyrPro: 1.551 ± 0.155
1.65TyrGln: 1.65 ± 0.129
1.869TyrArg: 1.869 ± 0.139
3.519TyrSer: 3.519 ± 0.208
2.634TyrThr: 2.634 ± 0.149
2.644TyrVal: 2.644 ± 0.167
0.736TyrTrp: 0.736 ± 0.074
2.336TyrTyr: 2.336 ± 0.187
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 244 proteins (100610 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski