Amino acid dipepetide frequency for Jeotgalibacillus malaysiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.61AlaAla: 6.61 ± 0.104	0.534AlaCys: 0.534 ± 0.022	4.186AlaAsp: 4.186 ± 0.066	5.989AlaGlu: 5.989 ± 0.093	3.423AlaPhe: 3.423 ± 0.072	6.251AlaGly: 6.251 ± 0.08	1.357AlaHis: 1.357 ± 0.037	5.31AlaIle: 5.31 ± 0.074	4.334AlaLys: 4.334 ± 0.068	7.209AlaLeu: 7.209 ± 0.097	2.195AlaMet: 2.195 ± 0.043	2.393AlaAsn: 2.393 ± 0.048	2.161AlaPro: 2.161 ± 0.044	2.132AlaGln: 2.132 ± 0.046	2.692AlaArg: 2.692 ± 0.053	4.284AlaSer: 4.284 ± 0.058	3.165AlaThr: 3.165 ± 0.057	6.129AlaVal: 6.129 ± 0.084	0.669AlaTrp: 0.669 ± 0.028	2.354AlaTyr: 2.354 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.39CysAla: 0.39 ± 0.02	0.068CysCys: 0.068 ± 0.009	0.361CysAsp: 0.361 ± 0.016	0.468CysGlu: 0.468 ± 0.021	0.245CysPhe: 0.245 ± 0.014	0.618CysGly: 0.618 ± 0.025	0.191CysHis: 0.191 ± 0.014	0.417CysIle: 0.417 ± 0.019	0.293CysLys: 0.293 ± 0.017	0.565CysLeu: 0.565 ± 0.024	0.168CysMet: 0.168 ± 0.01	0.216CysAsn: 0.216 ± 0.014	0.32CysPro: 0.32 ± 0.016	0.217CysGln: 0.217 ± 0.013	0.268CysArg: 0.268 ± 0.015	0.449CysSer: 0.449 ± 0.021	0.372CysThr: 0.372 ± 0.019	0.369CysVal: 0.369 ± 0.016	0.067CysTrp: 0.067 ± 0.008	0.238CysTyr: 0.238 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.718AspAla: 3.718 ± 0.059	0.407AspCys: 0.407 ± 0.02	2.834AspAsp: 2.834 ± 0.062	5.266AspGlu: 5.266 ± 0.076	2.541AspPhe: 2.541 ± 0.049	3.826AspGly: 3.826 ± 0.066	1.366AspHis: 1.366 ± 0.036	4.026AspIle: 4.026 ± 0.056	2.847AspLys: 2.847 ± 0.056	5.136AspLeu: 5.136 ± 0.076	1.561AspMet: 1.561 ± 0.038	1.794AspAsn: 1.794 ± 0.045	2.106AspPro: 2.106 ± 0.04	2.704AspGln: 2.704 ± 0.054	2.517AspArg: 2.517 ± 0.046	2.891AspSer: 2.891 ± 0.054	2.66AspThr: 2.66 ± 0.054	3.973AspVal: 3.973 ± 0.062	0.71AspTrp: 0.71 ± 0.025	2.285AspTyr: 2.285 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.2GluAla: 6.2 ± 0.092	0.427GluCys: 0.427 ± 0.023	4.534GluAsp: 4.534 ± 0.079	8.252GluGlu: 8.252 ± 0.143	2.713GluPhe: 2.713 ± 0.051	4.934GluGly: 4.934 ± 0.082	1.709GluHis: 1.709 ± 0.04	5.411GluIle: 5.411 ± 0.072	6.635GluLys: 6.635 ± 0.086	7.607GluLeu: 7.607 ± 0.087	2.687GluMet: 2.687 ± 0.051	3.607GluAsn: 3.607 ± 0.059	2.232GluPro: 2.232 ± 0.054	3.595GluGln: 3.595 ± 0.071	4.006GluArg: 4.006 ± 0.068	4.338GluSer: 4.338 ± 0.065	4.332GluThr: 4.332 ± 0.072	5.53GluVal: 5.53 ± 0.076	0.985GluTrp: 0.985 ± 0.03	2.369GluTyr: 2.369 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	2.994PheAla: 2.994 ± 0.058	0.296PheCys: 0.296 ± 0.016	2.583PheAsp: 2.583 ± 0.048	3.184PheGlu: 3.184 ± 0.053	2.265PhePhe: 2.265 ± 0.05	3.174PheGly: 3.174 ± 0.055	0.962PheHis: 0.962 ± 0.031	3.532PheIle: 3.532 ± 0.065	2.409PheLys: 2.409 ± 0.048	4.176PheLeu: 4.176 ± 0.066	1.214PheMet: 1.214 ± 0.034	1.939PheAsn: 1.939 ± 0.043	1.554PhePro: 1.554 ± 0.037	1.405PheGln: 1.405 ± 0.039	1.573PheArg: 1.573 ± 0.037	3.277PheSer: 3.277 ± 0.047	2.701PheThr: 2.701 ± 0.054	2.92PheVal: 2.92 ± 0.053	0.454PheTrp: 0.454 ± 0.021	1.707PheTyr: 1.707 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	5.027GlyAla: 5.027 ± 0.086	0.543GlyCys: 0.543 ± 0.022	3.689GlyAsp: 3.689 ± 0.068	5.198GlyGlu: 5.198 ± 0.073	3.404GlyPhe: 3.404 ± 0.047	5.035GlyGly: 5.035 ± 0.123	1.44GlyHis: 1.44 ± 0.037	5.26GlyIle: 5.26 ± 0.073	4.555GlyLys: 4.555 ± 0.068	6.559GlyLeu: 6.559 ± 0.1	2.23GlyMet: 2.23 ± 0.045	2.634GlyAsn: 2.634 ± 0.071	1.553GlyPro: 1.553 ± 0.047	2.274GlyGln: 2.274 ± 0.048	2.78GlyArg: 2.78 ± 0.052	4.261GlySer: 4.261 ± 0.071	4.107GlyThr: 4.107 ± 0.075	5.099GlyVal: 5.099 ± 0.07	0.85GlyTrp: 0.85 ± 0.028	2.834GlyTyr: 2.834 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.469HisAla: 1.469 ± 0.039	0.187HisCys: 0.187 ± 0.014	1.165HisAsp: 1.165 ± 0.035	1.603HisGlu: 1.603 ± 0.04	1.072HisPhe: 1.072 ± 0.03	1.456HisGly: 1.456 ± 0.038	0.692HisHis: 0.692 ± 0.027	1.49HisIle: 1.49 ± 0.043	1.06HisLys: 1.06 ± 0.032	2.109HisLeu: 2.109 ± 0.047	0.552HisMet: 0.552 ± 0.019	0.763HisAsn: 0.763 ± 0.026	1.122HisPro: 1.122 ± 0.032	0.921HisGln: 0.921 ± 0.032	0.913HisArg: 0.913 ± 0.025	1.277HisSer: 1.277 ± 0.034	1.118HisThr: 1.118 ± 0.032	1.494HisVal: 1.494 ± 0.035	0.209HisTrp: 0.209 ± 0.015	0.925HisTyr: 0.925 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.727IleAla: 5.727 ± 0.083	0.503IleCys: 0.503 ± 0.021	4.274IleAsp: 4.274 ± 0.065	5.893IleGlu: 5.893 ± 0.081	2.91IlePhe: 2.91 ± 0.06	5.305IleGly: 5.305 ± 0.081	1.685IleHis: 1.685 ± 0.045	4.748IleIle: 4.748 ± 0.077	3.983IleLys: 3.983 ± 0.065	6.533IleLeu: 6.533 ± 0.083	1.624IleMet: 1.624 ± 0.039	2.849IleAsn: 2.849 ± 0.047	2.902IlePro: 2.902 ± 0.048	2.861IleGln: 2.861 ± 0.051	3.249IleArg: 3.249 ± 0.058	4.794IleSer: 4.794 ± 0.069	4.02IleThr: 4.02 ± 0.055	4.909IleVal: 4.909 ± 0.072	0.596IleTrp: 0.596 ± 0.022	2.249IleTyr: 2.249 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.61LysAla: 4.61 ± 0.071	0.285LysCys: 0.285 ± 0.017	3.641LysAsp: 3.641 ± 0.064	6.457LysGlu: 6.457 ± 0.097	1.694LysPhe: 1.694 ± 0.044	4.383LysGly: 4.383 ± 0.062	1.42LysHis: 1.42 ± 0.032	3.941LysIle: 3.941 ± 0.066	5.987LysLys: 5.987 ± 0.094	5.158LysLeu: 5.158 ± 0.075	2.23LysMet: 2.23 ± 0.041	2.997LysAsn: 2.997 ± 0.047	2.16LysPro: 2.16 ± 0.045	2.719LysGln: 2.719 ± 0.043	3.372LysArg: 3.372 ± 0.056	3.554LysSer: 3.554 ± 0.06	3.636LysThr: 3.636 ± 0.057	4.363LysVal: 4.363 ± 0.069	0.806LysTrp: 0.806 ± 0.027	1.841LysTyr: 1.841 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	7.015LeuAla: 7.015 ± 0.096	0.51LeuCys: 0.51 ± 0.021	4.847LeuAsp: 4.847 ± 0.071	6.831LeuGlu: 6.831 ± 0.082	4.502LeuPhe: 4.502 ± 0.078	5.686LeuGly: 5.686 ± 0.088	1.942LeuHis: 1.942 ± 0.038	7.145LeuIle: 7.145 ± 0.092	6.487LeuLys: 6.487 ± 0.085	9.351LeuLeu: 9.351 ± 0.131	2.624LeuMet: 2.624 ± 0.048	4.264LeuAsn: 4.264 ± 0.064	3.768LeuPro: 3.768 ± 0.058	3.322LeuGln: 3.322 ± 0.063	3.527LeuArg: 3.527 ± 0.059	6.926LeuSer: 6.926 ± 0.079	5.858LeuThr: 5.858 ± 0.077	5.825LeuVal: 5.825 ± 0.089	0.766LeuTrp: 0.766 ± 0.028	3.192LeuTyr: 3.192 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.077MetAla: 2.077 ± 0.037	0.135MetCys: 0.135 ± 0.01	1.613MetAsp: 1.613 ± 0.037	2.088MetGlu: 2.088 ± 0.041	1.056MetPhe: 1.056 ± 0.033	1.7MetGly: 1.7 ± 0.036	0.457MetHis: 0.457 ± 0.019	2.324MetIle: 2.324 ± 0.051	2.84MetLys: 2.84 ± 0.042	2.662MetLeu: 2.662 ± 0.052	1.076MetMet: 1.076 ± 0.033	1.818MetAsn: 1.818 ± 0.038	1.037MetPro: 1.037 ± 0.034	0.975MetGln: 0.975 ± 0.031	1.187MetArg: 1.187 ± 0.031	1.812MetSer: 1.812 ± 0.041	2.023MetThr: 2.023 ± 0.037	1.824MetVal: 1.824 ± 0.041	0.192MetTrp: 0.192 ± 0.013	0.749MetTyr: 0.749 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.776AsnAla: 2.776 ± 0.048	0.258AsnCys: 0.258 ± 0.013	2.184AsnAsp: 2.184 ± 0.046	3.672AsnGlu: 3.672 ± 0.058	1.417AsnPhe: 1.417 ± 0.037	3.398AsnGly: 3.398 ± 0.08	0.975AsnHis: 0.975 ± 0.03	2.789AsnIle: 2.789 ± 0.048	2.436AsnLys: 2.436 ± 0.049	3.537AsnLeu: 3.537 ± 0.053	1.128AsnMet: 1.128 ± 0.03	1.597AsnAsn: 1.597 ± 0.047	1.925AsnPro: 1.925 ± 0.042	1.886AsnGln: 1.886 ± 0.041	2.021AsnArg: 2.021 ± 0.041	2.004AsnSer: 2.004 ± 0.052	2.009AsnThr: 2.009 ± 0.048	2.898AsnVal: 2.898 ± 0.056	0.47AsnTrp: 0.47 ± 0.021	1.299AsnTyr: 1.299 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	2.701ProAla: 2.701 ± 0.052	0.194ProCys: 0.194 ± 0.014	2.44ProAsp: 2.44 ± 0.048	3.477ProGlu: 3.477 ± 0.057	1.882ProPhe: 1.882 ± 0.036	2.441ProGly: 2.441 ± 0.049	0.773ProHis: 0.773 ± 0.027	2.227ProIle: 2.227 ± 0.045	1.81ProLys: 1.81 ± 0.04	3.358ProLeu: 3.358 ± 0.059	0.843ProMet: 0.843 ± 0.025	1.295ProAsn: 1.295 ± 0.036	0.996ProPro: 0.996 ± 0.032	1.001ProGln: 1.001 ± 0.034	1.028ProArg: 1.028 ± 0.033	2.251ProSer: 2.251 ± 0.046	1.623ProThr: 1.623 ± 0.043	3.193ProVal: 3.193 ± 0.058	0.326ProTrp: 0.326 ± 0.017	1.365ProTyr: 1.365 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.832GlnAla: 2.832 ± 0.051	0.173GlnCys: 0.173 ± 0.012	1.836GlnAsp: 1.836 ± 0.039	3.03GlnGlu: 3.03 ± 0.056	1.636GlnPhe: 1.636 ± 0.04	2.132GlnGly: 2.132 ± 0.054	0.883GlnHis: 0.883 ± 0.025	2.45GlnIle: 2.45 ± 0.048	2.587GlnLys: 2.587 ± 0.054	3.875GlnLeu: 3.875 ± 0.064	1.232GlnMet: 1.232 ± 0.033	1.478GlnAsn: 1.478 ± 0.038	1.303GlnPro: 1.303 ± 0.034	1.798GlnGln: 1.798 ± 0.047	1.508GlnArg: 1.508 ± 0.04	2.368GlnSer: 2.368 ± 0.042	2.135GlnThr: 2.135 ± 0.043	2.418GlnVal: 2.418 ± 0.049	0.413GlnTrp: 0.413 ± 0.018	1.352GlnTyr: 1.352 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.635ArgAla: 2.635 ± 0.051	0.249ArgCys: 0.249 ± 0.016	2.237ArgAsp: 2.237 ± 0.049	3.509ArgGlu: 3.509 ± 0.057	2.107ArgPhe: 2.107 ± 0.041	2.39ArgGly: 2.39 ± 0.046	0.933ArgHis: 0.933 ± 0.029	3.013ArgIle: 3.013 ± 0.048	3.142ArgLys: 3.142 ± 0.056	4.08ArgLeu: 4.08 ± 0.063	1.434ArgMet: 1.434 ± 0.035	1.803ArgAsn: 1.803 ± 0.038	1.332ArgPro: 1.332 ± 0.038	1.657ArgGln: 1.657 ± 0.042	1.823ArgArg: 1.823 ± 0.046	2.427ArgSer: 2.427 ± 0.046	2.129ArgThr: 2.129 ± 0.045	2.848ArgVal: 2.848 ± 0.052	0.412ArgTrp: 0.412 ± 0.017	1.55ArgTyr: 1.55 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.373SerAla: 4.373 ± 0.065	0.374SerCys: 0.374 ± 0.018	3.344SerAsp: 3.344 ± 0.053	4.537SerGlu: 4.537 ± 0.063	3.264SerPhe: 3.264 ± 0.056	4.981SerGly: 4.981 ± 0.08	1.238SerHis: 1.238 ± 0.032	4.774SerIle: 4.774 ± 0.068	3.53SerLys: 3.53 ± 0.069	5.94SerLeu: 5.94 ± 0.075	1.926SerMet: 1.926 ± 0.041	2.269SerAsn: 2.269 ± 0.047	2.201SerPro: 2.201 ± 0.046	1.945SerGln: 1.945 ± 0.046	2.448SerArg: 2.448 ± 0.045	4.055SerSer: 4.055 ± 0.085	3.137SerThr: 3.137 ± 0.056	4.502SerVal: 4.502 ± 0.064	0.642SerTrp: 0.642 ± 0.026	2.251SerTyr: 2.251 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	4.644ThrAla: 4.644 ± 0.075	0.334ThrCys: 0.334 ± 0.017	3.127ThrAsp: 3.127 ± 0.058	4.039ThrGlu: 4.039 ± 0.067	2.684ThrPhe: 2.684 ± 0.046	4.554ThrGly: 4.554 ± 0.069	1.076ThrHis: 1.076 ± 0.029	4.118ThrIle: 4.118 ± 0.061	2.924ThrLys: 2.924 ± 0.058	5.186ThrLeu: 5.186 ± 0.068	1.361ThrMet: 1.361 ± 0.032	2.152ThrAsn: 2.152 ± 0.057	2.324ThrPro: 2.324 ± 0.049	1.546ThrGln: 1.546 ± 0.032	1.86ThrArg: 1.86 ± 0.041	3.197ThrSer: 3.197 ± 0.056	2.789ThrThr: 2.789 ± 0.057	4.474ThrVal: 4.474 ± 0.069	0.513ThrTrp: 0.513 ± 0.026	1.957ThrTyr: 1.957 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	4.694ValAla: 4.694 ± 0.071	0.51ValCys: 0.51 ± 0.02	3.651ValAsp: 3.651 ± 0.067	5.174ValGlu: 5.174 ± 0.076	3.175ValPhe: 3.175 ± 0.052	4.138ValGly: 4.138 ± 0.062	1.381ValHis: 1.381 ± 0.032	5.565ValIle: 5.565 ± 0.081	4.812ValLys: 4.812 ± 0.057	6.895ValLeu: 6.895 ± 0.081	2.253ValMet: 2.253 ± 0.04	3.029ValAsn: 3.029 ± 0.051	2.679ValPro: 2.679 ± 0.049	2.481ValGln: 2.481 ± 0.043	2.875ValArg: 2.875 ± 0.046	4.855ValSer: 4.855 ± 0.064	4.48ValThr: 4.48 ± 0.081	4.85ValVal: 4.85 ± 0.072	0.691ValTrp: 0.691 ± 0.025	2.323ValTyr: 2.323 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.606TrpAla: 0.606 ± 0.024	0.076TrpCys: 0.076 ± 0.008	0.513TrpAsp: 0.513 ± 0.021	0.711TrpGlu: 0.711 ± 0.025	0.519TrpPhe: 0.519 ± 0.02	0.624TrpGly: 0.624 ± 0.022	0.238TrpHis: 0.238 ± 0.016	0.831TrpIle: 0.831 ± 0.028	0.682TrpLys: 0.682 ± 0.022	1.112TrpLeu: 1.112 ± 0.031	0.402TrpMet: 0.402 ± 0.017	0.468TrpAsn: 0.468 ± 0.023	0.231TrpPro: 0.231 ± 0.015	0.391TrpGln: 0.391 ± 0.019	0.437TrpArg: 0.437 ± 0.019	0.65TrpSer: 0.65 ± 0.025	0.633TrpThr: 0.633 ± 0.03	0.693TrpVal: 0.693 ± 0.023	0.136TrpTrp: 0.136 ± 0.011	0.318TrpTyr: 0.318 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.28TyrAla: 2.28 ± 0.047	0.238TyrCys: 0.238 ± 0.014	2.107TyrAsp: 2.107 ± 0.042	2.723TyrGlu: 2.723 ± 0.051	1.806TyrPhe: 1.806 ± 0.041	2.309TyrGly: 2.309 ± 0.042	0.88TyrHis: 0.88 ± 0.033	2.244TyrIle: 2.244 ± 0.05	1.902TyrLys: 1.902 ± 0.042	3.337TyrLeu: 3.337 ± 0.053	0.906TyrMet: 0.906 ± 0.029	1.313TyrAsn: 1.313 ± 0.037	1.318TyrPro: 1.318 ± 0.035	1.609TyrGln: 1.609 ± 0.039	1.625TyrArg: 1.625 ± 0.037	2.06TyrSer: 2.06 ± 0.045	1.932TyrThr: 1.932 ± 0.05	2.198TyrVal: 2.198 ± 0.042	0.365TyrTrp: 0.365 ± 0.018	1.322TyrTyr: 1.322 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4426 proteins (1165848 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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