Amino acid dipepetide frequency for Bean yellow dwarf virus (BeYDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.079AlaAla: 2.079 ± 1.951
1.04AlaCys: 1.04 ± 0.975
2.079AlaAsp: 2.079 ± 1.687
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
3.119AlaLys: 3.119 ± 2.253
4.158AlaLeu: 4.158 ± 0.932
0.0AlaMet: 0.0 ± 0.0
4.158AlaAsn: 4.158 ± 1.268
3.119AlaPro: 3.119 ± 2.253
1.04AlaGln: 1.04 ± 0.843
7.277AlaArg: 7.277 ± 2.544
5.198AlaSer: 5.198 ± 2.22
8.316AlaThr: 8.316 ± 1.561
1.04AlaVal: 1.04 ± 1.277
0.0AlaTrp: 0.0 ± 0.0
3.119AlaTyr: 3.119 ± 1.511
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.04CysAsp: 1.04 ± 0.803
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.079CysGly: 2.079 ± 0.825
3.119CysHis: 3.119 ± 0.44
3.119CysIle: 3.119 ± 1.24
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.119CysAsn: 3.119 ± 1.748
0.0CysPro: 0.0 ± 0.0
1.04CysGln: 1.04 ± 0.803
1.04CysArg: 1.04 ± 0.975
2.079CysSer: 2.079 ± 0.825
0.0CysThr: 0.0 ± 0.0
2.079CysVal: 2.079 ± 0.948
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.119AspAla: 3.119 ± 1.463
1.04AspCys: 1.04 ± 1.277
3.119AspAsp: 3.119 ± 1.393
3.119AspGlu: 3.119 ± 2.41
7.277AspPhe: 7.277 ± 2.544
5.198AspGly: 5.198 ± 2.145
3.119AspHis: 3.119 ± 1.24
5.198AspIle: 5.198 ± 1.214
3.119AspLys: 3.119 ± 0.44
8.316AspLeu: 8.316 ± 3.668
2.079AspMet: 2.079 ± 0.825
2.079AspAsn: 2.079 ± 0.948
4.158AspPro: 4.158 ± 0.932
2.079AspGln: 2.079 ± 1.687
0.0AspArg: 0.0 ± 0.0
2.079AspSer: 2.079 ± 1.951
3.119AspThr: 3.119 ± 2.074
2.079AspVal: 2.079 ± 1.951
1.04AspTrp: 1.04 ± 0.803
3.119AspTyr: 3.119 ± 1.393
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
4.158GluAsp: 4.158 ± 2.12
4.158GluGlu: 4.158 ± 1.651
2.079GluPhe: 2.079 ± 0.825
6.237GluGly: 6.237 ± 0.88
1.04GluHis: 1.04 ± 0.803
1.04GluIle: 1.04 ± 1.277
2.079GluLys: 2.079 ± 0.825
2.079GluLeu: 2.079 ± 0.825
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
2.079GluGln: 2.079 ± 0.825
2.079GluArg: 2.079 ± 1.502
5.198GluSer: 5.198 ± 1.214
3.119GluThr: 3.119 ± 1.393
1.04GluVal: 1.04 ± 0.843
4.158GluTrp: 4.158 ± 0.954
4.158GluTyr: 4.158 ± 1.651
0.0GluXaa: 0.0 ± 0.0
Phe
1.04PheAla: 1.04 ± 0.803
0.0PheCys: 0.0 ± 0.0
2.079PheAsp: 2.079 ± 0.825
4.158PheGlu: 4.158 ± 0.87
6.237PhePhe: 6.237 ± 1.406
2.079PheGly: 2.079 ± 2.554
1.04PheHis: 1.04 ± 0.975
1.04PheIle: 1.04 ± 0.843
4.158PheLys: 4.158 ± 1.907
9.356PheLeu: 9.356 ± 3.071
1.04PheMet: 1.04 ± 0.975
0.0PheAsn: 0.0 ± 0.0
7.277PhePro: 7.277 ± 0.702
2.079PheGln: 2.079 ± 0.825
6.237PheArg: 6.237 ± 0.88
2.079PheSer: 2.079 ± 1.951
4.158PheThr: 4.158 ± 2.12
2.079PheVal: 2.079 ± 0.948
1.04PheTrp: 1.04 ± 0.975
1.04PheTyr: 1.04 ± 1.277
0.0PheXaa: 0.0 ± 0.0
Gly
6.237GlyAla: 6.237 ± 5.852
1.04GlyCys: 1.04 ± 0.803
9.356GlyAsp: 9.356 ± 2.382
1.04GlyGlu: 1.04 ± 0.803
1.04GlyPhe: 1.04 ± 1.277
3.119GlyGly: 3.119 ± 1.748
0.0GlyHis: 0.0 ± 0.0
3.119GlyIle: 3.119 ± 1.748
4.158GlyLys: 4.158 ± 1.488
2.079GlyLeu: 2.079 ± 1.687
0.0GlyMet: 0.0 ± 0.0
3.119GlyAsn: 3.119 ± 0.44
6.237GlyPro: 6.237 ± 2.289
2.079GlyGln: 2.079 ± 1.55
2.079GlyArg: 2.079 ± 1.607
5.198GlySer: 5.198 ± 2.186
4.158GlyThr: 4.158 ± 1.651
5.198GlyVal: 5.198 ± 0.863
0.0GlyTrp: 0.0 ± 0.0
1.04GlyTyr: 1.04 ± 0.975
0.0GlyXaa: 0.0 ± 0.0
His
3.119HisAla: 3.119 ± 1.393
1.04HisCys: 1.04 ± 0.843
1.04HisAsp: 1.04 ± 0.803
4.158HisGlu: 4.158 ± 1.651
1.04HisPhe: 1.04 ± 0.975
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.079HisLys: 2.079 ± 0.825
2.079HisLeu: 2.079 ± 0.825
0.0HisMet: 0.0 ± 0.714
4.158HisAsn: 4.158 ± 0.87
5.198HisPro: 5.198 ± 1.675
2.079HisGln: 2.079 ± 0.825
1.04HisArg: 1.04 ± 0.975
0.0HisSer: 0.0 ± 0.0
1.04HisThr: 1.04 ± 0.975
1.04HisVal: 1.04 ± 0.843
0.0HisTrp: 0.0 ± 0.0
4.158HisTyr: 4.158 ± 0.87
0.0HisXaa: 0.0 ± 0.0
Ile
1.04IleAla: 1.04 ± 1.277
1.04IleCys: 1.04 ± 0.803
4.158IleAsp: 4.158 ± 0.87
0.0IleGlu: 0.0 ± 0.0
3.119IlePhe: 3.119 ± 0.44
2.079IleGly: 2.079 ± 1.26
1.04IleHis: 1.04 ± 0.843
5.198IleIle: 5.198 ± 2.145
7.277IleLys: 7.277 ± 1.121
4.158IleLeu: 4.158 ± 3.641
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
3.119IlePro: 3.119 ± 1.462
6.237IleGln: 6.237 ± 2.476
2.079IleArg: 2.079 ± 0.825
3.119IleSer: 3.119 ± 1.463
0.0IleThr: 0.0 ± 0.0
1.04IleVal: 1.04 ± 0.975
0.0IleTrp: 0.0 ± 0.0
1.04IleTyr: 1.04 ± 0.975
0.0IleXaa: 0.0 ± 0.0
Lys
2.079LysAla: 2.079 ± 1.55
2.079LysCys: 2.079 ± 0.825
4.158LysAsp: 4.158 ± 1.452
5.198LysGlu: 5.198 ± 0.893
4.158LysPhe: 4.158 ± 2.668
2.079LysGly: 2.079 ± 0.948
0.0LysHis: 0.0 ± 0.0
1.04LysIle: 1.04 ± 0.803
8.316LysLys: 8.316 ± 1.874
6.237LysLeu: 6.237 ± 2.476
0.0LysMet: 0.0 ± 0.0
4.158LysAsn: 4.158 ± 1.268
2.079LysPro: 2.079 ± 0.825
4.158LysGln: 4.158 ± 1.452
3.119LysArg: 3.119 ± 2.926
7.277LysSer: 7.277 ± 4.156
5.198LysThr: 5.198 ± 1.214
4.158LysVal: 4.158 ± 0.932
0.0LysTrp: 0.0 ± 0.0
3.119LysTyr: 3.119 ± 1.393
0.0LysXaa: 0.0 ± 0.0
Leu
1.04LeuAla: 1.04 ± 1.277
1.04LeuCys: 1.04 ± 0.803
7.277LeuAsp: 7.277 ± 1.663
4.158LeuGlu: 4.158 ± 2.241
7.277LeuPhe: 7.277 ± 1.964
5.198LeuGly: 5.198 ± 0.893
4.158LeuHis: 4.158 ± 1.651
5.198LeuIle: 5.198 ± 2.145
1.04LeuLys: 1.04 ± 1.277
1.04LeuLeu: 1.04 ± 1.277
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
0.0LeuPro: 0.0 ± 0.0
5.198LeuGln: 5.198 ± 0.893
2.079LeuArg: 2.079 ± 0.825
1.04LeuSer: 1.04 ± 0.803
5.198LeuThr: 5.198 ± 2.22
5.198LeuVal: 5.198 ± 2.942
3.119LeuTrp: 3.119 ± 1.393
6.237LeuTyr: 6.237 ± 1.132
0.0LeuXaa: 0.0 ± 0.0
Met
2.079MetAla: 2.079 ± 0.96
1.04MetCys: 1.04 ± 0.803
0.0MetAsp: 0.0 ± 0.0
1.04MetGlu: 1.04 ± 1.277
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.079MetIle: 2.079 ± 0.825
1.04MetLys: 1.04 ± 0.975
1.04MetLeu: 1.04 ± 0.803
0.0MetMet: 0.0 ± 0.0
1.04MetAsn: 1.04 ± 0.843
2.079MetPro: 2.079 ± 0.825
0.0MetGln: 0.0 ± 0.0
1.04MetArg: 1.04 ± 0.843
1.04MetSer: 1.04 ± 0.975
1.04MetThr: 1.04 ± 0.803
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
2.079AsnCys: 2.079 ± 0.948
1.04AsnAsp: 1.04 ± 0.975
0.0AsnGlu: 0.0 ± 0.0
3.119AsnPhe: 3.119 ± 0.44
3.119AsnGly: 3.119 ± 1.748
2.079AsnHis: 2.079 ± 0.825
3.119AsnIle: 3.119 ± 1.393
4.158AsnLys: 4.158 ± 1.268
0.0AsnLeu: 0.0 ± 0.0
1.04AsnMet: 1.04 ± 0.75
0.0AsnAsn: 0.0 ± 0.0
3.119AsnPro: 3.119 ± 1.462
3.119AsnGln: 3.119 ± 2.253
0.0AsnArg: 0.0 ± 0.0
3.119AsnSer: 3.119 ± 0.44
2.079AsnThr: 2.079 ± 0.96
1.04AsnVal: 1.04 ± 0.975
2.079AsnTrp: 2.079 ± 0.825
3.119AsnTyr: 3.119 ± 1.684
0.0AsnXaa: 0.0 ± 0.0
Pro
5.198ProAla: 5.198 ± 2.634
3.119ProCys: 3.119 ± 0.44
1.04ProAsp: 1.04 ± 0.803
3.119ProGlu: 3.119 ± 1.463
6.237ProPhe: 6.237 ± 1.406
5.198ProGly: 5.198 ± 2.837
3.119ProHis: 3.119 ± 0.44
1.04ProIle: 1.04 ± 0.843
3.119ProLys: 3.119 ± 1.393
1.04ProLeu: 1.04 ± 0.803
1.04ProMet: 1.04 ± 0.979
2.079ProAsn: 2.079 ± 0.825
5.198ProPro: 5.198 ± 2.388
3.119ProGln: 3.119 ± 0.44
3.119ProArg: 3.119 ± 0.44
13.514ProSer: 13.514 ± 1.196
3.119ProThr: 3.119 ± 0.44
1.04ProVal: 1.04 ± 0.843
1.04ProTrp: 1.04 ± 0.975
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.04GlnAla: 1.04 ± 0.843
0.0GlnCys: 0.0 ± 0.0
3.119GlnAsp: 3.119 ± 1.24
0.0GlnGlu: 0.0 ± 0.0
2.079GlnPhe: 2.079 ± 0.825
3.119GlnGly: 3.119 ± 2.253
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.079GlnLys: 2.079 ± 0.948
4.158GlnLeu: 4.158 ± 1.651
1.04GlnMet: 1.04 ± 0.771
0.0GlnAsn: 0.0 ± 0.0
4.158GlnPro: 4.158 ± 1.651
1.04GlnGln: 1.04 ± 0.803
3.119GlnArg: 3.119 ± 1.24
4.158GlnSer: 4.158 ± 1.651
4.158GlnThr: 4.158 ± 2.378
5.198GlnVal: 5.198 ± 1.45
2.079GlnTrp: 2.079 ± 0.825
2.079GlnTyr: 2.079 ± 0.825
0.0GlnXaa: 0.0 ± 0.0
Arg
2.079ArgAla: 2.079 ± 1.951
2.079ArgCys: 2.079 ± 0.825
6.237ArgAsp: 6.237 ± 2.476
5.198ArgGlu: 5.198 ± 0.893
1.04ArgPhe: 1.04 ± 0.975
3.119ArgGly: 3.119 ± 0.44
3.119ArgHis: 3.119 ± 1.462
1.04ArgIle: 1.04 ± 1.277
3.119ArgLys: 3.119 ± 0.44
3.119ArgLeu: 3.119 ± 0.44
1.04ArgMet: 1.04 ± 0.843
3.119ArgAsn: 3.119 ± 1.24
1.04ArgPro: 1.04 ± 0.843
0.0ArgGln: 0.0 ± 0.0
1.04ArgArg: 1.04 ± 0.975
3.119ArgSer: 3.119 ± 1.748
5.198ArgThr: 5.198 ± 1.993
1.04ArgVal: 1.04 ± 0.975
2.079ArgTrp: 2.079 ± 0.825
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.237SerAla: 6.237 ± 1.504
2.079SerCys: 2.079 ± 1.951
9.356SerAsp: 9.356 ± 2.003
2.079SerGlu: 2.079 ± 0.825
2.079SerPhe: 2.079 ± 0.825
4.158SerGly: 4.158 ± 2.655
3.119SerHis: 3.119 ± 0.44
2.079SerIle: 2.079 ± 0.825
11.435SerLys: 11.435 ± 3.284
4.158SerLeu: 4.158 ± 1.897
1.04SerMet: 1.04 ± 0.803
3.119SerAsn: 3.119 ± 1.741
8.316SerPro: 8.316 ± 1.908
6.237SerGln: 6.237 ± 1.998
3.119SerArg: 3.119 ± 2.926
14.553SerSer: 14.553 ± 2.543
6.237SerThr: 6.237 ± 2.879
3.119SerVal: 3.119 ± 2.253
1.04SerTrp: 1.04 ± 0.975
3.119SerTyr: 3.119 ± 1.511
0.0SerXaa: 0.0 ± 0.0
Thr
3.119ThrAla: 3.119 ± 1.24
0.0ThrCys: 0.0 ± 0.0
1.04ThrAsp: 1.04 ± 1.277
4.158ThrGlu: 4.158 ± 0.932
3.119ThrPhe: 3.119 ± 0.44
6.237ThrGly: 6.237 ± 0.88
5.198ThrHis: 5.198 ± 2.145
4.158ThrIle: 4.158 ± 0.87
3.119ThrLys: 3.119 ± 0.44
1.04ThrLeu: 1.04 ± 1.277
1.04ThrMet: 1.04 ± 0.843
3.119ThrAsn: 3.119 ± 1.289
5.198ThrPro: 5.198 ± 2.388
0.0ThrGln: 0.0 ± 0.0
4.158ThrArg: 4.158 ± 1.651
7.277ThrSer: 7.277 ± 2.269
9.356ThrThr: 9.356 ± 4.063
4.158ThrVal: 4.158 ± 2.668
4.158ThrTrp: 4.158 ± 2.668
4.158ThrTyr: 4.158 ± 0.87
0.0ThrXaa: 0.0 ± 0.0
Val
3.119ValAla: 3.119 ± 0.44
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.04ValGlu: 1.04 ± 0.975
5.198ValPhe: 5.198 ± 2.192
4.158ValGly: 4.158 ± 3.106
0.0ValHis: 0.0 ± 0.0
2.079ValIle: 2.079 ± 2.554
2.079ValLys: 2.079 ± 1.951
3.119ValLeu: 3.119 ± 0.44
0.0ValMet: 0.0 ± 0.0
2.079ValAsn: 2.079 ± 0.948
3.119ValPro: 3.119 ± 0.44
0.0ValGln: 0.0 ± 0.0
1.04ValArg: 1.04 ± 0.803
12.474ValSer: 12.474 ± 2.741
3.119ValThr: 3.119 ± 1.289
4.158ValVal: 4.158 ± 3.099
0.0ValTrp: 0.0 ± 0.0
3.119ValTyr: 3.119 ± 2.926
0.0ValXaa: 0.0 ± 0.0
Trp
3.119TrpAla: 3.119 ± 1.393
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.079TrpGlu: 2.079 ± 0.825
0.0TrpPhe: 0.0 ± 0.0
1.04TrpGly: 1.04 ± 0.975
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.079TrpLys: 2.079 ± 0.948
3.119TrpLeu: 3.119 ± 0.44
2.079TrpMet: 2.079 ± 0.825
1.04TrpAsn: 1.04 ± 0.803
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
4.158TrpArg: 4.158 ± 1.651
1.04TrpSer: 1.04 ± 0.975
3.119TrpThr: 3.119 ± 2.926
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
4.158TyrAsp: 4.158 ± 0.932
0.0TyrGlu: 0.0 ± 0.0
3.119TyrPhe: 3.119 ± 1.748
2.079TyrGly: 2.079 ± 0.948
4.158TyrHis: 4.158 ± 1.651
5.198TyrIle: 5.198 ± 1.214
1.04TyrLys: 1.04 ± 0.975
5.198TyrLeu: 5.198 ± 1.45
2.079TyrMet: 2.079 ± 0.948
1.04TyrAsn: 1.04 ± 0.803
2.079TyrPro: 2.079 ± 0.825
1.04TyrGln: 1.04 ± 1.277
0.0TyrArg: 0.0 ± 0.0
3.119TyrSer: 3.119 ± 1.24
2.079TyrThr: 2.079 ± 1.502
5.198TyrVal: 5.198 ± 0.893
1.04TyrTrp: 1.04 ± 0.803
1.04TyrTyr: 1.04 ± 0.975
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (963 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski