Amino acid dipepetide frequency for Wenzhou tombus-like virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.395AlaAla: 8.395 ± 4.178
0.0AlaCys: 0.0 ± 0.0
5.247AlaAsp: 5.247 ± 2.306
7.345AlaGlu: 7.345 ± 1.603
4.197AlaPhe: 4.197 ± 2.003
1.049AlaGly: 1.049 ± 0.783
1.049AlaHis: 1.049 ± 1.238
7.345AlaIle: 7.345 ± 0.776
2.099AlaLys: 2.099 ± 0.671
4.197AlaLeu: 4.197 ± 1.343
3.148AlaMet: 3.148 ± 1.272
2.099AlaAsn: 2.099 ± 1.044
2.099AlaPro: 2.099 ± 1.199
2.099AlaGln: 2.099 ± 1.429
5.247AlaArg: 5.247 ± 1.331
4.197AlaSer: 4.197 ± 0.658
5.247AlaThr: 5.247 ± 2.763
3.148AlaVal: 3.148 ± 1.272
1.049AlaTrp: 1.049 ± 0.714
2.099AlaTyr: 2.099 ± 1.044
0.0AlaXaa: 0.0 ± 0.0
Cys
1.049CysAla: 1.049 ± 0.783
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.099CysGlu: 2.099 ± 0.671
0.0CysPhe: 0.0 ± 0.0
2.099CysGly: 2.099 ± 1.429
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.099CysLeu: 2.099 ± 1.429
0.0CysMet: 0.0 ± 0.0
1.049CysAsn: 1.049 ± 0.714
1.049CysPro: 1.049 ± 0.714
1.049CysGln: 1.049 ± 0.714
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.099CysVal: 2.099 ± 1.429
0.0CysTrp: 0.0 ± 0.0
1.049CysTyr: 1.049 ± 0.783
0.0CysXaa: 0.0 ± 0.0
Asp
6.296AspAla: 6.296 ± 1.611
1.049AspCys: 1.049 ± 0.714
3.148AspAsp: 3.148 ± 1.537
5.247AspGlu: 5.247 ± 2.306
2.099AspPhe: 2.099 ± 1.044
1.049AspGly: 1.049 ± 0.714
0.0AspHis: 0.0 ± 0.0
3.148AspIle: 3.148 ± 1.272
2.099AspLys: 2.099 ± 1.429
4.197AspLeu: 4.197 ± 2.003
1.049AspMet: 1.049 ± 0.783
2.099AspAsn: 2.099 ± 1.199
3.148AspPro: 3.148 ± 1.537
1.049AspGln: 1.049 ± 0.714
1.049AspArg: 1.049 ± 1.238
7.345AspSer: 7.345 ± 2.73
2.099AspThr: 2.099 ± 1.566
3.148AspVal: 3.148 ± 1.272
0.0AspTrp: 0.0 ± 0.0
1.049AspTyr: 1.049 ± 1.238
0.0AspXaa: 0.0 ± 0.0
Glu
4.197GluAla: 4.197 ± 1.343
1.049GluCys: 1.049 ± 0.714
5.247GluAsp: 5.247 ± 0.108
12.592GluGlu: 12.592 ± 3.265
3.148GluPhe: 3.148 ± 0.567
2.099GluGly: 2.099 ± 1.566
4.197GluHis: 4.197 ± 0.757
3.148GluIle: 3.148 ± 1.272
5.247GluLys: 5.247 ± 1.735
7.345GluLeu: 7.345 ± 3.263
2.099GluMet: 2.099 ± 1.566
3.148GluAsn: 3.148 ± 0.567
4.197GluPro: 4.197 ± 0.658
3.148GluGln: 3.148 ± 2.153
4.197GluArg: 4.197 ± 0.658
5.247GluSer: 5.247 ± 4.756
2.099GluThr: 2.099 ± 2.477
5.247GluVal: 5.247 ± 2.306
1.049GluTrp: 1.049 ± 0.783
5.247GluTyr: 5.247 ± 1.331
0.0GluXaa: 0.0 ± 0.0
Phe
1.049PheAla: 1.049 ± 0.714
1.049PheCys: 1.049 ± 0.714
3.148PheAsp: 3.148 ± 1.144
2.099PheGlu: 2.099 ± 1.566
0.0PhePhe: 0.0 ± 0.0
4.197PheGly: 4.197 ± 2.075
1.049PheHis: 1.049 ± 0.714
0.0PheIle: 0.0 ± 0.0
3.148PheLys: 3.148 ± 1.144
3.148PheLeu: 3.148 ± 0.567
2.099PheMet: 2.099 ± 0.682
4.197PheAsn: 4.197 ± 1.785
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
1.049PheSer: 1.049 ± 0.783
2.099PheThr: 2.099 ± 1.566
3.148PheVal: 3.148 ± 0.567
0.0PheTrp: 0.0 ± 0.0
2.099PheTyr: 2.099 ± 1.199
0.0PheXaa: 0.0 ± 0.0
Gly
4.197GlyAla: 4.197 ± 2.003
0.0GlyCys: 0.0 ± 0.0
3.148GlyAsp: 3.148 ± 1.537
1.049GlyGlu: 1.049 ± 0.783
2.099GlyPhe: 2.099 ± 0.671
1.049GlyGly: 1.049 ± 1.238
2.099GlyHis: 2.099 ± 0.671
0.0GlyIle: 0.0 ± 0.0
3.148GlyLys: 3.148 ± 1.369
4.197GlyLeu: 4.197 ± 0.757
1.049GlyMet: 1.049 ± 0.917
2.099GlyAsn: 2.099 ± 1.429
2.099GlyPro: 2.099 ± 1.044
0.0GlyGln: 0.0 ± 0.0
3.148GlyArg: 3.148 ± 1.537
3.148GlySer: 3.148 ± 2.331
2.099GlyThr: 2.099 ± 1.199
6.296GlyVal: 6.296 ± 2.034
0.0GlyTrp: 0.0 ± 0.0
5.247GlyTyr: 5.247 ± 1.704
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.099HisAsp: 2.099 ± 0.671
0.0HisGlu: 0.0 ± 0.0
1.049HisPhe: 1.049 ± 0.714
0.0HisGly: 0.0 ± 0.0
2.099HisHis: 2.099 ± 0.671
2.099HisIle: 2.099 ± 1.566
4.197HisLys: 4.197 ± 1.971
2.099HisLeu: 2.099 ± 1.429
1.049HisMet: 1.049 ± 0.783
0.0HisAsn: 0.0 ± 0.0
1.049HisPro: 1.049 ± 0.714
2.099HisGln: 2.099 ± 0.671
3.148HisArg: 3.148 ± 1.272
2.099HisSer: 2.099 ± 0.671
3.148HisThr: 3.148 ± 0.567
1.049HisVal: 1.049 ± 0.714
0.0HisTrp: 0.0 ± 0.0
1.049HisTyr: 1.049 ± 0.714
0.0HisXaa: 0.0 ± 0.0
Ile
4.197IleAla: 4.197 ± 1.785
3.148IleCys: 3.148 ± 2.143
2.099IleAsp: 2.099 ± 0.671
5.247IleGlu: 5.247 ± 1.521
1.049IlePhe: 1.049 ± 0.714
5.247IleGly: 5.247 ± 1.877
0.0IleHis: 0.0 ± 0.0
4.197IleIle: 4.197 ± 1.785
5.247IleLys: 5.247 ± 0.108
3.148IleLeu: 3.148 ± 2.143
3.148IleMet: 3.148 ± 1.632
2.099IleAsn: 2.099 ± 0.671
5.247IlePro: 5.247 ± 0.108
2.099IleGln: 2.099 ± 1.566
1.049IleArg: 1.049 ± 0.714
5.247IleSer: 5.247 ± 3.044
1.049IleThr: 1.049 ± 0.783
1.049IleVal: 1.049 ± 1.238
0.0IleTrp: 0.0 ± 0.0
4.197IleTyr: 4.197 ± 0.757
0.0IleXaa: 0.0 ± 0.0
Lys
5.247LysAla: 5.247 ± 1.521
0.0LysCys: 0.0 ± 0.0
3.148LysAsp: 3.148 ± 1.144
1.049LysGlu: 1.049 ± 1.238
1.049LysPhe: 1.049 ± 0.714
2.099LysGly: 2.099 ± 1.044
2.099LysHis: 2.099 ± 0.671
2.099LysIle: 2.099 ± 1.566
5.247LysLys: 5.247 ± 1.331
8.395LysLeu: 8.395 ± 2.685
2.099LysMet: 2.099 ± 0.671
3.148LysAsn: 3.148 ± 1.272
4.197LysPro: 4.197 ± 0.658
1.049LysGln: 1.049 ± 0.783
6.296LysArg: 6.296 ± 1.135
3.148LysSer: 3.148 ± 0.567
5.247LysThr: 5.247 ± 1.704
4.197LysVal: 4.197 ± 1.343
1.049LysTrp: 1.049 ± 0.714
1.049LysTyr: 1.049 ± 0.783
0.0LysXaa: 0.0 ± 0.0
Leu
5.247LeuAla: 5.247 ± 3.916
2.099LeuCys: 2.099 ± 0.671
4.197LeuAsp: 4.197 ± 1.971
8.395LeuGlu: 8.395 ± 2.685
2.099LeuPhe: 2.099 ± 1.429
4.197LeuGly: 4.197 ± 1.343
2.099LeuHis: 2.099 ± 1.566
4.197LeuIle: 4.197 ± 1.343
3.148LeuLys: 3.148 ± 1.144
6.296LeuLeu: 6.296 ± 0.823
1.049LeuMet: 1.049 ± 0.714
5.247LeuAsn: 5.247 ± 0.108
4.197LeuPro: 4.197 ± 2.089
7.345LeuGln: 7.345 ± 2.912
2.099LeuArg: 2.099 ± 0.671
7.345LeuSer: 7.345 ± 2.892
5.247LeuThr: 5.247 ± 0.108
4.197LeuVal: 4.197 ± 0.658
2.099LeuTrp: 2.099 ± 1.566
2.099LeuTyr: 2.099 ± 1.199
0.0LeuXaa: 0.0 ± 0.0
Met
4.197MetAla: 4.197 ± 3.133
1.049MetCys: 1.049 ± 0.714
0.0MetAsp: 0.0 ± 0.0
1.049MetGlu: 1.049 ± 1.238
2.099MetPhe: 2.099 ± 0.671
1.049MetGly: 1.049 ± 0.714
1.049MetHis: 1.049 ± 0.714
3.148MetIle: 3.148 ± 1.144
2.099MetLys: 2.099 ± 1.044
2.099MetLeu: 2.099 ± 0.671
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
4.197MetArg: 4.197 ± 2.003
4.197MetSer: 4.197 ± 1.785
0.0MetThr: 0.0 ± 0.0
3.148MetVal: 3.148 ± 1.144
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.247AsnAla: 5.247 ± 0.108
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
4.197AsnGlu: 4.197 ± 0.757
1.049AsnPhe: 1.049 ± 1.238
2.099AsnGly: 2.099 ± 1.429
1.049AsnHis: 1.049 ± 0.783
2.099AsnIle: 2.099 ± 1.429
3.148AsnLys: 3.148 ± 1.144
1.049AsnLeu: 1.049 ± 0.783
1.049AsnMet: 1.049 ± 0.714
4.197AsnAsn: 4.197 ± 2.075
3.148AsnPro: 3.148 ± 1.537
0.0AsnGln: 0.0 ± 0.0
4.197AsnArg: 4.197 ± 2.089
1.049AsnSer: 1.049 ± 0.714
3.148AsnThr: 3.148 ± 0.567
2.099AsnVal: 2.099 ± 1.199
0.0AsnTrp: 0.0 ± 0.0
2.099AsnTyr: 2.099 ± 1.566
0.0AsnXaa: 0.0 ± 0.0
Pro
1.049ProAla: 1.049 ± 0.783
1.049ProCys: 1.049 ± 0.783
2.099ProAsp: 2.099 ± 1.199
5.247ProGlu: 5.247 ± 1.521
0.0ProPhe: 0.0 ± 0.0
4.197ProGly: 4.197 ± 4.953
1.049ProHis: 1.049 ± 0.714
5.247ProIle: 5.247 ± 1.359
1.049ProLys: 1.049 ± 0.714
1.049ProLeu: 1.049 ± 0.783
0.0ProMet: 0.0 ± 0.0
1.049ProAsn: 1.049 ± 1.238
4.197ProPro: 4.197 ± 4.953
3.148ProGln: 3.148 ± 1.272
4.197ProArg: 4.197 ± 2.398
4.197ProSer: 4.197 ± 1.971
4.197ProThr: 4.197 ± 1.343
6.296ProVal: 6.296 ± 3.163
0.0ProTrp: 0.0 ± 0.0
2.099ProTyr: 2.099 ± 1.044
0.0ProXaa: 0.0 ± 0.0
Gln
3.148GlnAla: 3.148 ± 0.567
2.099GlnCys: 2.099 ± 0.671
0.0GlnAsp: 0.0 ± 0.0
2.099GlnGlu: 2.099 ± 1.044
1.049GlnPhe: 1.049 ± 0.714
3.148GlnGly: 3.148 ± 1.537
4.197GlnHis: 4.197 ± 1.343
1.049GlnIle: 1.049 ± 0.714
4.197GlnLys: 4.197 ± 1.971
2.099GlnLeu: 2.099 ± 1.429
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.049GlnPro: 1.049 ± 0.714
1.049GlnGln: 1.049 ± 0.714
0.0GlnArg: 0.0 ± 0.0
7.345GlnSer: 7.345 ± 3.263
1.049GlnThr: 1.049 ± 1.238
2.099GlnVal: 2.099 ± 1.566
1.049GlnTrp: 1.049 ± 0.714
1.049GlnTyr: 1.049 ± 0.783
0.0GlnXaa: 0.0 ± 0.0
Arg
5.247ArgAla: 5.247 ± 0.108
1.049ArgCys: 1.049 ± 0.714
3.148ArgAsp: 3.148 ± 1.369
3.148ArgGlu: 3.148 ± 1.272
3.148ArgPhe: 3.148 ± 1.144
1.049ArgGly: 1.049 ± 1.238
2.099ArgHis: 2.099 ± 1.566
5.247ArgIle: 5.247 ± 3.493
2.099ArgLys: 2.099 ± 1.199
4.197ArgLeu: 4.197 ± 0.757
6.296ArgMet: 6.296 ± 0.782
2.099ArgAsn: 2.099 ± 1.199
3.148ArgPro: 3.148 ± 1.537
2.099ArgGln: 2.099 ± 1.044
3.148ArgArg: 3.148 ± 1.144
5.247ArgSer: 5.247 ± 1.331
3.148ArgThr: 3.148 ± 0.567
2.099ArgVal: 2.099 ± 1.044
2.099ArgTrp: 2.099 ± 1.566
4.197ArgTyr: 4.197 ± 0.757
0.0ArgXaa: 0.0 ± 0.0
Ser
4.197SerAla: 4.197 ± 1.806
0.0SerCys: 0.0 ± 0.0
2.099SerAsp: 2.099 ± 2.477
3.148SerGlu: 3.148 ± 2.153
5.247SerPhe: 5.247 ± 1.359
3.148SerGly: 3.148 ± 2.143
2.099SerHis: 2.099 ± 1.429
6.296SerIle: 6.296 ± 3.074
2.099SerLys: 2.099 ± 1.566
8.395SerLeu: 8.395 ± 2.615
2.099SerMet: 2.099 ± 1.429
1.049SerAsn: 1.049 ± 1.238
4.197SerPro: 4.197 ± 2.003
4.197SerGln: 4.197 ± 2.089
8.395SerArg: 8.395 ± 2.045
4.197SerSer: 4.197 ± 1.343
3.148SerThr: 3.148 ± 1.144
4.197SerVal: 4.197 ± 2.398
1.049SerTrp: 1.049 ± 0.783
4.197SerTyr: 4.197 ± 0.757
0.0SerXaa: 0.0 ± 0.0
Thr
3.148ThrAla: 3.148 ± 0.567
0.0ThrCys: 0.0 ± 0.0
3.148ThrAsp: 3.148 ± 0.567
4.197ThrGlu: 4.197 ± 1.343
0.0ThrPhe: 0.0 ± 0.0
4.197ThrGly: 4.197 ± 2.089
1.049ThrHis: 1.049 ± 0.783
4.197ThrIle: 4.197 ± 1.806
3.148ThrLys: 3.148 ± 1.272
9.444ThrLeu: 9.444 ± 3.246
1.049ThrMet: 1.049 ± 0.783
1.049ThrAsn: 1.049 ± 0.783
2.099ThrPro: 2.099 ± 1.199
3.148ThrGln: 3.148 ± 1.144
3.148ThrArg: 3.148 ± 1.144
2.099ThrSer: 2.099 ± 1.199
3.148ThrThr: 3.148 ± 0.567
4.197ThrVal: 4.197 ± 1.343
0.0ThrTrp: 0.0 ± 0.0
1.049ThrTyr: 1.049 ± 1.238
0.0ThrXaa: 0.0 ± 0.0
Val
3.148ValAla: 3.148 ± 1.272
0.0ValCys: 0.0 ± 0.0
6.296ValAsp: 6.296 ± 2.014
7.345ValGlu: 7.345 ± 1.603
2.099ValPhe: 2.099 ± 0.671
1.049ValGly: 1.049 ± 1.238
1.049ValHis: 1.049 ± 0.783
3.148ValIle: 3.148 ± 2.143
7.345ValLys: 7.345 ± 0.947
4.197ValLeu: 4.197 ± 0.757
0.0ValMet: 0.0 ± 0.0
2.099ValAsn: 2.099 ± 0.671
2.099ValPro: 2.099 ± 1.199
4.197ValGln: 4.197 ± 2.003
4.197ValArg: 4.197 ± 1.343
5.247ValSer: 5.247 ± 2.662
5.247ValThr: 5.247 ± 2.662
5.247ValVal: 5.247 ± 3.044
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.049TrpAla: 1.049 ± 0.714
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.148TrpGlu: 3.148 ± 1.144
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.049TrpLeu: 1.049 ± 0.783
1.049TrpMet: 1.049 ± 0.783
1.049TrpAsn: 1.049 ± 0.783
2.099TrpPro: 2.099 ± 1.566
0.0TrpGln: 0.0 ± 0.0
2.099TrpArg: 2.099 ± 1.199
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.049TrpTrp: 1.049 ± 0.783
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.049TyrAla: 1.049 ± 0.783
0.0TyrCys: 0.0 ± 0.0
2.099TyrAsp: 2.099 ± 1.429
5.247TyrGlu: 5.247 ± 3.044
2.099TyrPhe: 2.099 ± 0.671
3.148TyrGly: 3.148 ± 0.567
0.0TyrHis: 0.0 ± 0.0
3.148TyrIle: 3.148 ± 1.272
3.148TyrLys: 3.148 ± 2.331
4.197TyrLeu: 4.197 ± 3.133
0.0TyrMet: 0.0 ± 0.0
3.148TyrAsn: 3.148 ± 1.537
2.099TyrPro: 2.099 ± 1.044
0.0TyrGln: 0.0 ± 0.0
4.197TyrArg: 4.197 ± 2.398
1.049TyrSer: 1.049 ± 0.783
2.099TyrThr: 2.099 ± 1.044
1.049TyrVal: 1.049 ± 0.783
2.099TyrTrp: 2.099 ± 1.199
2.099TyrTyr: 2.099 ± 0.671
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (954 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski