Amino acid dipepetide frequency for CRESS virus sp. ctfsu28

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.681AlaAla: 3.681 ± 0.292
0.0AlaCys: 0.0 ± 0.0
8.589AlaAsp: 8.589 ± 3.456
3.681AlaGlu: 3.681 ± 2.82
3.681AlaPhe: 3.681 ± 3.529
3.681AlaGly: 3.681 ± 2.055
1.227AlaHis: 1.227 ± 1.176
7.362AlaIle: 7.362 ± 1.47
3.681AlaLys: 3.681 ± 1.636
4.908AlaLeu: 4.908 ± 0.658
0.0AlaMet: 0.0 ± 0.0
2.454AlaAsn: 2.454 ± 2.279
2.454AlaPro: 2.454 ± 2.279
3.681AlaGln: 3.681 ± 2.055
1.227AlaArg: 1.227 ± 0.94
8.589AlaSer: 8.589 ± 3.287
2.454AlaThr: 2.454 ± 2.279
7.362AlaVal: 7.362 ± 2.291
0.0AlaTrp: 0.0 ± 0.0
1.227AlaTyr: 1.227 ± 0.94
0.0AlaXaa: 0.0 ± 0.0
Cys
3.681CysAla: 3.681 ± 0.292
0.0CysCys: 0.0 ± 0.0
1.227CysAsp: 1.227 ± 0.94
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.454CysGly: 2.454 ± 1.88
1.227CysHis: 1.227 ± 0.94
2.454CysIle: 2.454 ± 1.0
0.0CysLys: 0.0 ± 0.0
2.454CysLeu: 2.454 ± 1.0
0.0CysMet: 0.0 ± 0.0
2.454CysAsn: 2.454 ± 1.071
0.0CysPro: 0.0 ± 0.0
1.227CysGln: 1.227 ± 1.14
3.681CysArg: 3.681 ± 0.292
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.227CysVal: 1.227 ± 0.94
0.0CysTrp: 0.0 ± 0.0
1.227CysTyr: 1.227 ± 0.94
0.0CysXaa: 0.0 ± 0.0
Asp
8.589AspAla: 8.589 ± 4.08
1.227AspCys: 1.227 ± 1.176
0.0AspAsp: 0.0 ± 0.0
3.681AspGlu: 3.681 ± 1.636
2.454AspPhe: 2.454 ± 1.071
8.589AspGly: 8.589 ± 2.102
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
1.227AspLys: 1.227 ± 0.94
7.362AspLeu: 7.362 ± 4.18
8.589AspMet: 8.589 ± 3.456
3.681AspAsn: 3.681 ± 2.055
4.908AspPro: 4.908 ± 1.392
4.908AspGln: 4.908 ± 3.196
2.454AspArg: 2.454 ± 1.88
4.908AspSer: 4.908 ± 2.388
3.681AspThr: 3.681 ± 2.116
3.681AspVal: 3.681 ± 2.055
1.227AspTrp: 1.227 ± 0.94
1.227AspTyr: 1.227 ± 1.14
0.0AspXaa: 0.0 ± 0.0
Glu
1.227GluAla: 1.227 ± 1.176
2.454GluCys: 2.454 ± 1.88
4.908GluAsp: 4.908 ± 0.658
3.681GluGlu: 3.681 ± 2.82
3.681GluPhe: 3.681 ± 1.636
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
2.454GluIle: 2.454 ± 1.0
4.908GluLys: 4.908 ± 3.76
2.454GluLeu: 2.454 ± 1.226
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
2.454GluPro: 2.454 ± 1.226
1.227GluGln: 1.227 ± 1.14
1.227GluArg: 1.227 ± 0.94
1.227GluSer: 1.227 ± 0.94
1.227GluThr: 1.227 ± 0.94
3.681GluVal: 3.681 ± 1.571
2.454GluTrp: 2.454 ± 1.88
4.908GluTyr: 4.908 ± 2.388
0.0GluXaa: 0.0 ± 0.0
Phe
2.454PheAla: 2.454 ± 1.0
0.0PheCys: 0.0 ± 0.0
2.454PheAsp: 2.454 ± 2.353
0.0PheGlu: 0.0 ± 0.0
1.227PhePhe: 1.227 ± 0.94
2.454PheGly: 2.454 ± 1.0
3.681PheHis: 3.681 ± 2.116
2.454PheIle: 2.454 ± 2.353
3.681PheLys: 3.681 ± 1.927
2.454PheLeu: 2.454 ± 1.0
1.227PheMet: 1.227 ± 0.953
1.227PheAsn: 1.227 ± 1.14
1.227PhePro: 1.227 ± 1.176
2.454PheGln: 2.454 ± 1.226
3.681PheArg: 3.681 ± 0.292
4.908PheSer: 4.908 ± 3.196
0.0PheThr: 0.0 ± 0.0
1.227PheVal: 1.227 ± 0.94
0.0PheTrp: 0.0 ± 0.0
3.681PheTyr: 3.681 ± 0.292
0.0PheXaa: 0.0 ± 0.0
Gly
7.362GlyAla: 7.362 ± 2.291
1.227GlyCys: 1.227 ± 1.14
6.135GlyAsp: 6.135 ± 4.7
3.681GlyGlu: 3.681 ± 1.571
1.227GlyPhe: 1.227 ± 1.176
6.135GlyGly: 6.135 ± 2.461
1.227GlyHis: 1.227 ± 0.94
3.681GlyIle: 3.681 ± 0.292
4.908GlyLys: 4.908 ± 2.388
4.908GlyLeu: 4.908 ± 2.453
0.0GlyMet: 0.0 ± 0.0
2.454GlyAsn: 2.454 ± 2.353
2.454GlyPro: 2.454 ± 1.0
1.227GlyGln: 1.227 ± 1.176
6.135GlyArg: 6.135 ± 1.515
6.135GlySer: 6.135 ± 1.08
11.043GlyThr: 11.043 ± 0.875
7.362GlyVal: 7.362 ± 2.395
1.227GlyTrp: 1.227 ± 0.94
2.454GlyTyr: 2.454 ± 1.88
0.0GlyXaa: 0.0 ± 0.0
His
1.227HisAla: 1.227 ± 1.14
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.227HisGlu: 1.227 ± 0.94
1.227HisPhe: 1.227 ± 1.176
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.454HisIle: 2.454 ± 1.88
2.454HisLys: 2.454 ± 1.071
1.227HisLeu: 1.227 ± 0.94
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.227HisArg: 1.227 ± 0.94
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.454HisVal: 2.454 ± 2.353
1.227HisTrp: 1.227 ± 0.94
1.227HisTyr: 1.227 ± 1.14
0.0HisXaa: 0.0 ± 0.0
Ile
3.681IleAla: 3.681 ± 0.292
1.227IleCys: 1.227 ± 1.176
4.908IleAsp: 4.908 ± 0.658
4.908IleGlu: 4.908 ± 0.658
1.227IlePhe: 1.227 ± 1.14
7.362IleGly: 7.362 ± 2.16
0.0IleHis: 0.0 ± 0.0
4.908IleIle: 4.908 ± 2.142
2.454IleLys: 2.454 ± 1.0
1.227IleLeu: 1.227 ± 1.176
0.0IleMet: 0.0 ± 0.0
1.227IleAsn: 1.227 ± 1.14
2.454IlePro: 2.454 ± 1.88
0.0IleGln: 0.0 ± 0.0
2.454IleArg: 2.454 ± 1.88
1.227IleSer: 1.227 ± 1.14
3.681IleThr: 3.681 ± 0.292
6.135IleVal: 6.135 ± 1.08
0.0IleTrp: 0.0 ± 0.0
1.227IleTyr: 1.227 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
2.454LysAla: 2.454 ± 1.0
1.227LysCys: 1.227 ± 0.94
6.135LysAsp: 6.135 ± 0.887
6.135LysGlu: 6.135 ± 3.272
2.454LysPhe: 2.454 ± 1.0
4.908LysGly: 4.908 ± 0.658
2.454LysHis: 2.454 ± 1.88
3.681LysIle: 3.681 ± 2.82
3.681LysLys: 3.681 ± 3.419
1.227LysLeu: 1.227 ± 1.14
3.681LysMet: 3.681 ± 1.636
4.908LysAsn: 4.908 ± 3.76
0.0LysPro: 0.0 ± 0.0
2.454LysGln: 2.454 ± 1.071
7.362LysArg: 7.362 ± 1.933
1.227LysSer: 1.227 ± 0.94
0.0LysThr: 0.0 ± 0.0
4.908LysVal: 4.908 ± 4.559
2.454LysTrp: 2.454 ± 1.071
4.908LysTyr: 4.908 ± 2.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.908LeuAla: 4.908 ± 0.658
0.0LeuCys: 0.0 ± 0.0
6.135LeuAsp: 6.135 ± 3.044
2.454LeuGlu: 2.454 ± 1.0
2.454LeuPhe: 2.454 ± 1.226
4.908LeuGly: 4.908 ± 3.158
2.454LeuHis: 2.454 ± 1.88
6.135LeuIle: 6.135 ± 0.887
8.589LeuLys: 8.589 ± 1.454
1.227LeuLeu: 1.227 ± 0.94
1.227LeuMet: 1.227 ± 1.14
4.908LeuAsn: 4.908 ± 2.0
0.0LeuPro: 0.0 ± 0.0
1.227LeuGln: 1.227 ± 0.94
1.227LeuArg: 1.227 ± 0.94
3.681LeuSer: 3.681 ± 2.055
3.681LeuThr: 3.681 ± 1.636
3.681LeuVal: 3.681 ± 0.292
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.681MetAla: 3.681 ± 2.116
1.227MetCys: 1.227 ± 1.14
3.681MetAsp: 3.681 ± 0.292
1.227MetGlu: 1.227 ± 1.176
0.0MetPhe: 0.0 ± 0.0
1.227MetGly: 1.227 ± 1.176
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.454MetLys: 2.454 ± 1.88
2.454MetLeu: 2.454 ± 1.88
0.0MetMet: 0.0 ± 0.0
2.454MetAsn: 2.454 ± 1.071
0.0MetPro: 0.0 ± 0.0
2.454MetGln: 2.454 ± 1.226
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.227MetVal: 1.227 ± 1.176
1.227MetTrp: 1.227 ± 0.94
2.454MetTyr: 2.454 ± 1.071
0.0MetXaa: 0.0 ± 0.0
Asn
1.227AsnAla: 1.227 ± 1.14
1.227AsnCys: 1.227 ± 1.14
1.227AsnAsp: 1.227 ± 1.176
2.454AsnGlu: 2.454 ± 1.88
0.0AsnPhe: 0.0 ± 0.0
3.681AsnGly: 3.681 ± 2.055
0.0AsnHis: 0.0 ± 0.0
1.227AsnIle: 1.227 ± 1.14
2.454AsnLys: 2.454 ± 1.88
8.589AsnLeu: 8.589 ± 0.392
0.0AsnMet: 0.0 ± 0.0
3.681AsnAsn: 3.681 ± 1.571
3.681AsnPro: 3.681 ± 0.292
1.227AsnGln: 1.227 ± 1.14
2.454AsnArg: 2.454 ± 1.88
7.362AsnSer: 7.362 ± 3.679
7.362AsnThr: 7.362 ± 2.291
2.454AsnVal: 2.454 ± 1.88
0.0AsnTrp: 0.0 ± 0.0
3.681AsnTyr: 3.681 ± 1.571
0.0AsnXaa: 0.0 ± 0.0
Pro
4.908ProAla: 4.908 ± 1.392
0.0ProCys: 0.0 ± 0.0
3.681ProAsp: 3.681 ± 1.571
1.227ProGlu: 1.227 ± 1.176
2.454ProPhe: 2.454 ± 1.88
4.908ProGly: 4.908 ± 3.004
1.227ProHis: 1.227 ± 0.94
0.0ProIle: 0.0 ± 0.0
0.0ProLys: 0.0 ± 0.0
2.454ProLeu: 2.454 ± 1.88
0.0ProMet: 0.0 ± 0.0
3.681ProAsn: 3.681 ± 2.055
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
2.454ProArg: 2.454 ± 1.226
2.454ProSer: 2.454 ± 2.353
2.454ProThr: 2.454 ± 2.279
3.681ProVal: 3.681 ± 0.292
0.0ProTrp: 0.0 ± 0.0
1.227ProTyr: 1.227 ± 0.94
0.0ProXaa: 0.0 ± 0.0
Gln
2.454GlnAla: 2.454 ± 1.226
1.227GlnCys: 1.227 ± 0.94
2.454GlnAsp: 2.454 ± 1.226
2.454GlnGlu: 2.454 ± 1.071
0.0GlnPhe: 0.0 ± 0.0
4.908GlnGly: 4.908 ± 3.088
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.227GlnLys: 1.227 ± 0.94
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
3.681GlnAsn: 3.681 ± 2.055
0.0GlnPro: 0.0 ± 0.0
4.908GlnGln: 4.908 ± 2.453
2.454GlnArg: 2.454 ± 1.226
1.227GlnSer: 1.227 ± 1.176
4.908GlnThr: 4.908 ± 2.453
3.681GlnVal: 3.681 ± 2.055
1.227GlnTrp: 1.227 ± 1.176
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
1.227ArgCys: 1.227 ± 1.176
2.454ArgAsp: 2.454 ± 1.071
1.227ArgGlu: 1.227 ± 1.14
3.681ArgPhe: 3.681 ± 2.055
2.454ArgGly: 2.454 ± 1.0
0.0ArgHis: 0.0 ± 0.0
6.135ArgIle: 6.135 ± 2.561
6.135ArgLys: 6.135 ± 0.887
3.681ArgLeu: 3.681 ± 0.292
1.227ArgMet: 1.227 ± 0.94
2.454ArgAsn: 2.454 ± 1.88
2.454ArgPro: 2.454 ± 1.88
1.227ArgGln: 1.227 ± 1.176
2.454ArgArg: 2.454 ± 2.353
3.681ArgSer: 3.681 ± 1.636
2.454ArgThr: 2.454 ± 1.0
7.362ArgVal: 7.362 ± 1.312
2.454ArgTrp: 2.454 ± 1.88
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.908SerAla: 4.908 ± 3.004
1.227SerCys: 1.227 ± 0.94
1.227SerAsp: 1.227 ± 1.176
1.227SerGlu: 1.227 ± 1.14
8.589SerPhe: 8.589 ± 3.287
6.135SerGly: 6.135 ± 3.044
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.908SerLys: 4.908 ± 2.388
1.227SerLeu: 1.227 ± 1.176
1.227SerMet: 1.227 ± 0.94
4.908SerAsn: 4.908 ± 3.158
3.681SerPro: 3.681 ± 2.044
2.454SerGln: 2.454 ± 2.279
2.454SerArg: 2.454 ± 1.071
7.362SerSer: 7.362 ± 5.466
1.227SerThr: 1.227 ± 0.94
4.908SerVal: 4.908 ± 3.196
3.681SerTrp: 3.681 ± 2.055
2.454SerTyr: 2.454 ± 1.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.908ThrAla: 4.908 ± 2.453
1.227ThrCys: 1.227 ± 1.14
1.227ThrAsp: 1.227 ± 1.14
1.227ThrGlu: 1.227 ± 1.14
0.0ThrPhe: 0.0 ± 0.0
6.135ThrGly: 6.135 ± 0.887
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
2.454ThrLys: 2.454 ± 1.071
3.681ThrLeu: 3.681 ± 2.116
0.0ThrMet: 0.0 ± 0.0
4.908ThrAsn: 4.908 ± 2.0
6.135ThrPro: 6.135 ± 2.399
2.454ThrGln: 2.454 ± 1.071
2.454ThrArg: 2.454 ± 1.071
3.681ThrSer: 3.681 ± 0.292
3.681ThrThr: 3.681 ± 2.055
4.908ThrVal: 4.908 ± 1.273
1.227ThrTrp: 1.227 ± 0.94
4.908ThrTyr: 4.908 ± 1.392
0.0ThrXaa: 0.0 ± 0.0
Val
4.908ValAla: 4.908 ± 1.273
1.227ValCys: 1.227 ± 1.14
7.362ValAsp: 7.362 ± 1.933
1.227ValGlu: 1.227 ± 0.94
3.681ValPhe: 3.681 ± 2.055
8.589ValGly: 8.589 ± 4.052
2.454ValHis: 2.454 ± 1.226
3.681ValIle: 3.681 ± 2.116
4.908ValLys: 4.908 ± 3.004
7.362ValLeu: 7.362 ± 2.395
6.135ValMet: 6.135 ± 2.501
2.454ValAsn: 2.454 ± 1.0
2.454ValPro: 2.454 ± 2.279
2.454ValGln: 2.454 ± 1.226
4.908ValArg: 4.908 ± 2.453
1.227ValSer: 1.227 ± 1.14
3.681ValThr: 3.681 ± 0.292
11.043ValVal: 11.043 ± 3.85
0.0ValTrp: 0.0 ± 0.0
6.135ValTyr: 6.135 ± 2.601
0.0ValXaa: 0.0 ± 0.0
Trp
1.227TrpAla: 1.227 ± 1.14
2.454TrpCys: 2.454 ± 1.88
3.681TrpAsp: 3.681 ± 1.571
1.227TrpGlu: 1.227 ± 0.94
2.454TrpPhe: 2.454 ± 2.353
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.227TrpAsn: 1.227 ± 0.94
1.227TrpPro: 1.227 ± 0.94
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
3.681TrpSer: 3.681 ± 1.636
0.0TrpThr: 0.0 ± 0.0
1.227TrpVal: 1.227 ± 0.94
1.227TrpTrp: 1.227 ± 0.94
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.454TyrAla: 2.454 ± 1.88
4.908TyrCys: 4.908 ± 3.76
4.908TyrAsp: 4.908 ± 3.158
1.227TyrGlu: 1.227 ± 0.94
0.0TyrPhe: 0.0 ± 0.0
2.454TyrGly: 2.454 ± 1.071
0.0TyrHis: 0.0 ± 0.0
3.681TyrIle: 3.681 ± 1.571
6.135TyrLys: 6.135 ± 2.851
0.0TyrLeu: 0.0 ± 0.0
1.227TyrMet: 1.227 ± 0.776
1.227TyrAsn: 1.227 ± 1.14
1.227TyrPro: 1.227 ± 0.94
1.227TyrGln: 1.227 ± 1.14
2.454TyrArg: 2.454 ± 1.88
1.227TyrSer: 1.227 ± 0.94
3.681TyrThr: 3.681 ± 0.292
4.908TyrVal: 4.908 ± 1.273
0.0TyrTrp: 0.0 ± 0.0
3.681TyrTyr: 3.681 ± 2.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (816 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski