Amino acid dipepetide frequency for Hubei virga-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.05AlaAla: 2.05 ± 1.934
0.0AlaCys: 0.0 ± 0.0
2.05AlaAsp: 2.05 ± 0.763
1.538AlaGlu: 1.538 ± 0.484
2.05AlaPhe: 2.05 ± 2.691
2.05AlaGly: 2.05 ± 0.763
2.05AlaHis: 2.05 ± 1.499
1.025AlaIle: 1.025 ± 1.158
3.588AlaLys: 3.588 ± 0.916
4.613AlaLeu: 4.613 ± 1.503
3.075AlaMet: 3.075 ± 1.185
1.538AlaAsn: 1.538 ± 0.907
2.05AlaPro: 2.05 ± 0.763
0.0AlaGln: 0.0 ± 0.0
0.513AlaArg: 0.513 ± 0.508
3.075AlaSer: 3.075 ± 1.61
2.05AlaThr: 2.05 ± 1.299
3.588AlaVal: 3.588 ± 3.034
0.0AlaTrp: 0.0 ± 0.0
3.075AlaTyr: 3.075 ± 0.967
0.0AlaXaa: 0.0 ± 0.0
Cys
1.538CysAla: 1.538 ± 1.04
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.513CysGlu: 0.513 ± 0.508
0.0CysPhe: 0.0 ± 0.0
1.025CysGly: 1.025 ± 0.693
0.0CysHis: 0.0 ± 0.0
0.513CysIle: 0.513 ± 0.347
1.538CysLys: 1.538 ± 0.484
1.025CysLeu: 1.025 ± 1.158
0.0CysMet: 0.0 ± 0.0
1.025CysAsn: 1.025 ± 0.355
1.025CysPro: 1.025 ± 0.355
0.0CysGln: 0.0 ± 0.0
0.513CysArg: 0.513 ± 0.508
1.538CysSer: 1.538 ± 0.484
0.513CysThr: 0.513 ± 0.347
1.025CysVal: 1.025 ± 0.693
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.638AspAla: 5.638 ± 1.364
0.513AspCys: 0.513 ± 0.508
5.126AspAsp: 5.126 ± 1.548
2.05AspGlu: 2.05 ± 1.387
3.075AspPhe: 3.075 ± 1.821
1.538AspGly: 1.538 ± 0.484
1.538AspHis: 1.538 ± 0.484
7.688AspIle: 7.688 ± 3.732
9.739AspLys: 9.739 ± 1.99
6.151AspLeu: 6.151 ± 1.713
2.563AspMet: 2.563 ± 0.774
0.513AspAsn: 0.513 ± 0.347
2.05AspPro: 2.05 ± 0.796
2.563AspGln: 2.563 ± 1.805
2.563AspArg: 2.563 ± 1.278
4.613AspSer: 4.613 ± 1.794
2.563AspThr: 2.563 ± 0.84
4.613AspVal: 4.613 ± 1.886
0.0AspTrp: 0.0 ± 0.0
2.563AspTyr: 2.563 ± 0.88
0.0AspXaa: 0.0 ± 0.0
Glu
1.538GluAla: 1.538 ± 2.034
1.025GluCys: 1.025 ± 0.693
2.05GluAsp: 2.05 ± 2.524
2.05GluGlu: 2.05 ± 1.387
3.075GluPhe: 3.075 ± 0.967
1.025GluGly: 1.025 ± 0.355
1.538GluHis: 1.538 ± 1.04
5.126GluIle: 5.126 ± 1.303
5.638GluLys: 5.638 ± 3.091
5.126GluLeu: 5.126 ± 0.939
1.025GluMet: 1.025 ± 0.355
1.538GluAsn: 1.538 ± 0.484
0.513GluPro: 0.513 ± 0.508
1.025GluGln: 1.025 ± 0.693
1.538GluArg: 1.538 ± 0.484
4.613GluSer: 4.613 ± 1.451
3.075GluThr: 3.075 ± 0.967
2.05GluVal: 2.05 ± 0.71
0.0GluTrp: 0.0 ± 0.0
5.638GluTyr: 5.638 ± 1.537
0.0GluXaa: 0.0 ± 0.0
Phe
2.05PheAla: 2.05 ± 1.123
1.025PheCys: 1.025 ± 0.693
4.1PheAsp: 4.1 ± 0.871
5.126PheGlu: 5.126 ± 2.356
2.563PhePhe: 2.563 ± 1.082
2.05PheGly: 2.05 ± 0.763
0.0PheHis: 0.0 ± 0.0
3.075PheIle: 3.075 ± 1.064
4.1PheLys: 4.1 ± 1.66
4.613PheLeu: 4.613 ± 0.812
2.05PheMet: 2.05 ± 1.108
4.613PheAsn: 4.613 ± 1.262
1.538PhePro: 1.538 ± 2.034
1.025PheGln: 1.025 ± 1.158
1.025PheArg: 1.025 ± 0.693
5.126PheSer: 5.126 ± 2.557
6.151PheThr: 6.151 ± 3.22
1.025PheVal: 1.025 ± 1.016
0.0PheTrp: 0.0 ± 0.0
2.05PheTyr: 2.05 ± 0.744
0.0PheXaa: 0.0 ± 0.0
Gly
0.513GlyAla: 0.513 ± 0.347
1.025GlyCys: 1.025 ± 0.355
4.613GlyAsp: 4.613 ± 3.12
1.538GlyGlu: 1.538 ± 0.484
1.538GlyPhe: 1.538 ± 1.04
0.513GlyGly: 0.513 ± 0.347
0.513GlyHis: 0.513 ± 0.508
2.05GlyIle: 2.05 ± 0.796
2.563GlyLys: 2.563 ± 1.733
4.613GlyLeu: 4.613 ± 1.676
0.513GlyMet: 0.513 ± 0.508
2.05GlyAsn: 2.05 ± 0.71
0.513GlyPro: 0.513 ± 1.092
0.513GlyGln: 0.513 ± 0.508
1.538GlyArg: 1.538 ± 0.958
3.075GlySer: 3.075 ± 2.657
1.025GlyThr: 1.025 ± 0.355
5.638GlyVal: 5.638 ± 2.322
0.0GlyTrp: 0.0 ± 0.0
1.025GlyTyr: 1.025 ± 1.016
0.0GlyXaa: 0.0 ± 0.0
His
1.538HisAla: 1.538 ± 0.931
0.0HisCys: 0.0 ± 0.0
0.513HisAsp: 0.513 ± 0.347
1.538HisGlu: 1.538 ± 1.004
0.0HisPhe: 0.0 ± 0.0
1.025HisGly: 1.025 ± 0.693
1.025HisHis: 1.025 ± 1.756
1.025HisIle: 1.025 ± 0.693
0.513HisLys: 0.513 ± 0.347
2.05HisLeu: 2.05 ± 1.126
0.0HisMet: 0.0 ± 0.0
0.513HisAsn: 0.513 ± 0.508
0.513HisPro: 0.513 ± 0.508
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
4.613HisSer: 4.613 ± 2.695
2.563HisThr: 2.563 ± 0.88
1.025HisVal: 1.025 ± 0.967
0.513HisTrp: 0.513 ± 1.092
1.538HisTyr: 1.538 ± 0.484
0.0HisXaa: 0.0 ± 0.0
Ile
2.563IleAla: 2.563 ± 1.136
0.513IleCys: 0.513 ± 0.508
6.663IleAsp: 6.663 ± 2.503
3.588IleGlu: 3.588 ± 1.999
3.588IlePhe: 3.588 ± 0.724
3.588IleGly: 3.588 ± 1.622
1.538IleHis: 1.538 ± 1.004
5.638IleIle: 5.638 ± 0.768
8.201IleLys: 8.201 ± 2.122
4.613IleLeu: 4.613 ± 1.676
1.538IleMet: 1.538 ± 1.012
5.638IleAsn: 5.638 ± 2.74
5.126IlePro: 5.126 ± 1.037
2.05IleGln: 2.05 ± 1.126
2.563IleArg: 2.563 ± 0.88
4.613IleSer: 4.613 ± 1.752
4.1IleThr: 4.1 ± 1.936
5.638IleVal: 5.638 ± 1.988
0.513IleTrp: 0.513 ± 0.347
3.588IleTyr: 3.588 ± 0.916
0.0IleXaa: 0.0 ± 0.0
Lys
3.588LysAla: 3.588 ± 1.638
1.025LysCys: 1.025 ± 0.355
4.613LysAsp: 4.613 ± 1.824
2.563LysGlu: 2.563 ± 1.082
6.663LysPhe: 6.663 ± 0.119
3.075LysGly: 3.075 ± 1.814
1.025LysHis: 1.025 ± 0.693
5.638LysIle: 5.638 ± 1.918
3.588LysLys: 3.588 ± 1.752
6.663LysLeu: 6.663 ± 1.409
0.513LysMet: 0.513 ± 0.347
5.126LysAsn: 5.126 ± 1.995
4.1LysPro: 4.1 ± 2.093
2.563LysGln: 2.563 ± 0.723
4.613LysArg: 4.613 ± 2.415
8.201LysSer: 8.201 ± 2.122
7.176LysThr: 7.176 ± 2.197
3.075LysVal: 3.075 ± 0.857
0.0LysTrp: 0.0 ± 0.0
5.126LysTyr: 5.126 ± 2.164
0.0LysXaa: 0.0 ± 0.0
Leu
3.075LeuAla: 3.075 ± 1.124
1.538LeuCys: 1.538 ± 1.04
6.663LeuAsp: 6.663 ± 1.687
6.151LeuGlu: 6.151 ± 1.822
6.151LeuPhe: 6.151 ± 1.455
1.025LeuGly: 1.025 ± 0.355
2.563LeuHis: 2.563 ± 1.082
6.663LeuIle: 6.663 ± 1.217
11.276LeuLys: 11.276 ± 1.934
10.764LeuLeu: 10.764 ± 0.642
3.075LeuMet: 3.075 ± 0.727
6.663LeuAsn: 6.663 ± 1.601
3.075LeuPro: 3.075 ± 0.727
4.1LeuGln: 4.1 ± 0.807
2.563LeuArg: 2.563 ± 0.88
10.251LeuSer: 10.251 ± 1.713
6.151LeuThr: 6.151 ± 2.34
4.613LeuVal: 4.613 ± 0.713
0.513LeuTrp: 0.513 ± 0.347
2.563LeuTyr: 2.563 ± 1.329
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.563MetAsp: 2.563 ± 1.136
0.513MetGlu: 0.513 ± 0.347
1.538MetPhe: 1.538 ± 1.04
1.025MetGly: 1.025 ± 0.355
0.513MetHis: 0.513 ± 0.508
0.513MetIle: 0.513 ± 0.347
2.563MetLys: 2.563 ± 1.801
3.075MetLeu: 3.075 ± 0.65
0.513MetMet: 0.513 ± 0.508
2.563MetAsn: 2.563 ± 1.858
1.025MetPro: 1.025 ± 1.155
0.0MetGln: 0.0 ± 0.0
1.025MetArg: 1.025 ± 0.967
3.588MetSer: 3.588 ± 1.103
2.05MetThr: 2.05 ± 1.123
2.05MetVal: 2.05 ± 0.71
0.0MetTrp: 0.0 ± 0.0
0.513MetTyr: 0.513 ± 1.1
0.0MetXaa: 0.0 ± 0.0
Asn
3.588AsnAla: 3.588 ± 2.1
0.0AsnCys: 0.0 ± 0.0
4.1AsnAsp: 4.1 ± 1.526
2.05AsnGlu: 2.05 ± 0.763
2.05AsnPhe: 2.05 ± 0.744
3.075AsnGly: 3.075 ± 1.197
0.513AsnHis: 0.513 ± 1.1
6.663AsnIle: 6.663 ± 2.011
3.588AsnLys: 3.588 ± 1.103
7.176AsnLeu: 7.176 ± 2.391
2.05AsnMet: 2.05 ± 0.71
6.151AsnAsn: 6.151 ± 3.272
1.538AsnPro: 1.538 ± 0.931
3.075AsnGln: 3.075 ± 0.942
3.588AsnArg: 3.588 ± 1.017
4.613AsnSer: 4.613 ± 1.824
2.563AsnThr: 2.563 ± 1.801
5.126AsnVal: 5.126 ± 0.958
1.025AsnTrp: 1.025 ± 0.693
2.563AsnTyr: 2.563 ± 0.8
0.0AsnXaa: 0.0 ± 0.0
Pro
0.513ProAla: 0.513 ± 0.508
0.0ProCys: 0.0 ± 0.0
3.588ProAsp: 3.588 ± 1.752
3.075ProGlu: 3.075 ± 1.459
2.563ProPhe: 2.563 ± 2.373
2.05ProGly: 2.05 ± 0.763
0.0ProHis: 0.0 ± 0.0
2.563ProIle: 2.563 ± 0.723
1.025ProLys: 1.025 ± 0.355
4.1ProLeu: 4.1 ± 2.54
1.025ProMet: 1.025 ± 1.016
2.563ProAsn: 2.563 ± 1.858
1.025ProPro: 1.025 ± 1.016
0.513ProGln: 0.513 ± 0.508
1.538ProArg: 1.538 ± 0.805
4.1ProSer: 4.1 ± 1.241
0.513ProThr: 0.513 ± 1.1
2.05ProVal: 2.05 ± 0.71
0.0ProTrp: 0.0 ± 0.0
2.563ProTyr: 2.563 ± 0.723
0.0ProXaa: 0.0 ± 0.0
Gln
0.513GlnAla: 0.513 ± 0.508
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.513GlnGlu: 0.513 ± 1.092
1.538GlnPhe: 1.538 ± 1.411
2.05GlnGly: 2.05 ± 1.387
1.025GlnHis: 1.025 ± 0.995
2.05GlnIle: 2.05 ± 0.763
0.513GlnLys: 0.513 ± 0.347
4.613GlnLeu: 4.613 ± 2.695
1.025GlnMet: 1.025 ± 0.561
1.538GlnAsn: 1.538 ± 1.004
0.513GlnPro: 0.513 ± 0.347
0.513GlnGln: 0.513 ± 1.092
1.025GlnArg: 1.025 ± 0.355
1.025GlnSer: 1.025 ± 0.693
2.05GlnThr: 2.05 ± 1.499
3.075GlnVal: 3.075 ± 0.727
0.513GlnTrp: 0.513 ± 0.347
1.538GlnTyr: 1.538 ± 1.04
0.0GlnXaa: 0.0 ± 0.0
Arg
1.538ArgAla: 1.538 ± 2.069
0.513ArgCys: 0.513 ± 0.347
3.588ArgAsp: 3.588 ± 0.916
2.563ArgGlu: 2.563 ± 0.774
2.05ArgPhe: 2.05 ± 1.068
1.025ArgGly: 1.025 ± 0.355
2.05ArgHis: 2.05 ± 0.763
2.05ArgIle: 2.05 ± 1.108
2.05ArgLys: 2.05 ± 0.71
4.613ArgLeu: 4.613 ± 1.444
1.538ArgMet: 1.538 ± 1.525
3.075ArgAsn: 3.075 ± 1.064
1.025ArgPro: 1.025 ± 0.355
2.05ArgGln: 2.05 ± 1.499
3.075ArgArg: 3.075 ± 1.064
1.538ArgSer: 1.538 ± 0.484
4.1ArgThr: 4.1 ± 3.334
2.05ArgVal: 2.05 ± 0.744
0.513ArgTrp: 0.513 ± 1.1
2.563ArgTyr: 2.563 ± 1.329
0.0ArgXaa: 0.0 ± 0.0
Ser
2.05SerAla: 2.05 ± 0.71
1.538SerCys: 1.538 ± 1.04
5.126SerAsp: 5.126 ± 2.277
3.588SerGlu: 3.588 ± 1.229
5.126SerPhe: 5.126 ± 2.253
2.563SerGly: 2.563 ± 1.082
1.538SerHis: 1.538 ± 0.958
6.663SerIle: 6.663 ± 2.148
6.151SerLys: 6.151 ± 2.828
7.176SerLeu: 7.176 ± 4.61
2.05SerMet: 2.05 ± 1.068
7.176SerAsn: 7.176 ± 2.791
1.538SerPro: 1.538 ± 0.484
3.588SerGln: 3.588 ± 1.172
5.638SerArg: 5.638 ± 1.79
6.663SerSer: 6.663 ± 3.031
4.613SerThr: 4.613 ± 1.824
5.126SerVal: 5.126 ± 1.351
0.513SerTrp: 0.513 ± 1.1
4.613SerTyr: 4.613 ± 1.84
0.0SerXaa: 0.0 ± 0.0
Thr
2.563ThrAla: 2.563 ± 2.203
1.538ThrCys: 1.538 ± 0.805
4.1ThrAsp: 4.1 ± 1.15
3.588ThrGlu: 3.588 ± 2.616
2.563ThrPhe: 2.563 ± 1.136
1.025ThrGly: 1.025 ± 0.355
1.538ThrHis: 1.538 ± 2.19
8.201ThrIle: 8.201 ± 3.301
5.638ThrLys: 5.638 ± 1.618
7.688ThrLeu: 7.688 ± 1.424
0.513ThrMet: 0.513 ± 0.347
2.05ThrAsn: 2.05 ± 1.775
3.588ThrPro: 3.588 ± 2.15
1.025ThrGln: 1.025 ± 0.693
3.588ThrArg: 3.588 ± 1.622
3.588ThrSer: 3.588 ± 1.483
9.226ThrThr: 9.226 ± 4.329
1.538ThrVal: 1.538 ± 0.484
1.025ThrTrp: 1.025 ± 0.967
3.588ThrTyr: 3.588 ± 0.724
0.0ThrXaa: 0.0 ± 0.0
Val
2.563ValAla: 2.563 ± 0.723
1.538ValCys: 1.538 ± 0.931
5.126ValAsp: 5.126 ± 2.277
2.563ValGlu: 2.563 ± 0.723
3.075ValPhe: 3.075 ± 0.942
2.563ValGly: 2.563 ± 1.733
1.025ValHis: 1.025 ± 0.995
3.588ValIle: 3.588 ± 1.172
3.588ValLys: 3.588 ± 0.617
7.176ValLeu: 7.176 ± 2.043
1.025ValMet: 1.025 ± 0.835
6.151ValAsn: 6.151 ± 1.872
2.563ValPro: 2.563 ± 0.723
0.513ValGln: 0.513 ± 0.347
2.563ValArg: 2.563 ± 1.278
2.563ValSer: 2.563 ± 0.774
3.075ValThr: 3.075 ± 1.688
4.613ValVal: 4.613 ± 2.435
1.025ValTrp: 1.025 ± 0.967
4.613ValTyr: 4.613 ± 1.426
0.0ValXaa: 0.0 ± 0.0
Trp
0.513TrpAla: 0.513 ± 1.092
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.513TrpGlu: 0.513 ± 0.347
0.513TrpPhe: 0.513 ± 0.347
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.025TrpIle: 1.025 ± 0.995
0.513TrpLys: 0.513 ± 0.347
0.0TrpLeu: 0.0 ± 0.0
0.513TrpMet: 0.513 ± 0.347
0.513TrpAsn: 0.513 ± 0.347
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.513TrpArg: 0.513 ± 0.347
0.513TrpSer: 0.513 ± 0.347
0.513TrpThr: 0.513 ± 1.092
1.025TrpVal: 1.025 ± 1.756
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.05TyrAla: 2.05 ± 1.458
0.0TyrCys: 0.0 ± 0.0
3.075TyrAsp: 3.075 ± 0.857
3.588TyrGlu: 3.588 ± 1.229
3.588TyrPhe: 3.588 ± 1.752
3.075TyrGly: 3.075 ± 0.857
0.513TyrHis: 0.513 ± 1.1
4.1TyrIle: 4.1 ± 1.15
2.563TyrLys: 2.563 ± 1.136
3.588TyrLeu: 3.588 ± 1.172
0.513TyrMet: 0.513 ± 0.508
4.1TyrAsn: 4.1 ± 1.419
2.05TyrPro: 2.05 ± 0.796
1.025TyrGln: 1.025 ± 0.693
3.588TyrArg: 3.588 ± 1.739
5.126TyrSer: 5.126 ± 2.164
4.1TyrThr: 4.1 ± 2.688
2.563TyrVal: 2.563 ± 1.733
0.513TyrTrp: 0.513 ± 0.347
3.588TyrTyr: 3.588 ± 1.172
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1952 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski