Amino acid dipepetide frequency for Minicystis rosea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.607AlaAla: 19.607 ± 0.125	2.079AlaCys: 2.079 ± 0.041	6.741AlaAsp: 6.741 ± 0.049	7.746AlaGlu: 7.746 ± 0.071	4.226AlaPhe: 4.226 ± 0.032	11.059AlaGly: 11.059 ± 0.06	2.9AlaHis: 2.9 ± 0.025	5.261AlaIle: 5.261 ± 0.037	3.858AlaLys: 3.858 ± 0.041	14.685AlaLeu: 14.685 ± 0.085	2.66AlaMet: 2.66 ± 0.032	2.232AlaAsn: 2.232 ± 0.025	9.274AlaPro: 9.274 ± 0.072	3.535AlaGln: 3.535 ± 0.034	12.038AlaArg: 12.038 ± 0.084	8.287AlaSer: 8.287 ± 0.06	7.057AlaThr: 7.057 ± 0.051	9.32AlaVal: 9.32 ± 0.056	1.872AlaTrp: 1.872 ± 0.019	2.428AlaTyr: 2.428 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	1.72CysAla: 1.72 ± 0.033	0.197CysCys: 0.197 ± 0.009	0.984CysAsp: 0.984 ± 0.025	0.653CysGlu: 0.653 ± 0.014	0.379CysPhe: 0.379 ± 0.01	1.531CysGly: 1.531 ± 0.044	0.345CysHis: 0.345 ± 0.013	0.382CysIle: 0.382 ± 0.01	0.368CysLys: 0.368 ± 0.011	0.86CysLeu: 0.86 ± 0.015	0.18CysMet: 0.18 ± 0.007	0.442CysAsn: 0.442 ± 0.02	0.777CysPro: 0.777 ± 0.019	0.388CysGln: 0.388 ± 0.013	0.756CysArg: 0.756 ± 0.015	0.944CysSer: 0.944 ± 0.024	0.924CysThr: 0.924 ± 0.03	0.964CysVal: 0.964 ± 0.024	0.168CysTrp: 0.168 ± 0.01	0.226CysTyr: 0.226 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	8.401AspAla: 8.401 ± 0.06	0.762AspCys: 0.762 ± 0.022	3.937AspAsp: 3.937 ± 0.038	3.812AspGlu: 3.812 ± 0.032	1.801AspPhe: 1.801 ± 0.02	6.158AspGly: 6.158 ± 0.067	1.267AspHis: 1.267 ± 0.018	1.878AspIle: 1.878 ± 0.021	1.469AspLys: 1.469 ± 0.024	6.008AspLeu: 6.008 ± 0.046	0.804AspMet: 0.804 ± 0.012	0.984AspAsn: 0.984 ± 0.015	4.297AspPro: 4.297 ± 0.034	1.331AspGln: 1.331 ± 0.019	4.544AspArg: 4.544 ± 0.038	1.803AspSer: 1.803 ± 0.021	2.621AspThr: 2.621 ± 0.026	4.928AspVal: 4.928 ± 0.04	0.662AspTrp: 0.662 ± 0.012	1.014AspTyr: 1.014 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	8.152GluAla: 8.152 ± 0.067	0.483GluCys: 0.483 ± 0.012	2.722GluAsp: 2.722 ± 0.03	3.23GluGlu: 3.23 ± 0.043	0.912GluPhe: 0.912 ± 0.014	4.731GluGly: 4.731 ± 0.032	1.538GluHis: 1.538 ± 0.02	2.939GluIle: 2.939 ± 0.03	1.889GluLys: 1.889 ± 0.028	5.826GluLeu: 5.826 ± 0.043	1.137GluMet: 1.137 ± 0.017	1.025GluAsn: 1.025 ± 0.014	3.398GluPro: 3.398 ± 0.03	1.944GluGln: 1.944 ± 0.022	5.694GluArg: 5.694 ± 0.052	2.688GluSer: 2.688 ± 0.024	2.829GluThr: 2.829 ± 0.026	4.238GluVal: 4.238 ± 0.033	0.606GluTrp: 0.606 ± 0.013	0.828GluTyr: 0.828 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	4.191PheAla: 4.191 ± 0.031	0.392PheCys: 0.392 ± 0.01	2.36PheAsp: 2.36 ± 0.024	1.987PheGlu: 1.987 ± 0.024	1.179PhePhe: 1.179 ± 0.017	3.186PheGly: 3.186 ± 0.026	0.755PheHis: 0.755 ± 0.012	0.986PheIle: 0.986 ± 0.014	0.672PheLys: 0.672 ± 0.015	2.688PheLeu: 2.688 ± 0.026	0.531PheMet: 0.531 ± 0.01	0.652PheAsn: 0.652 ± 0.015	1.523PhePro: 1.523 ± 0.021	0.857PheGln: 0.857 ± 0.013	2.112PheArg: 2.112 ± 0.026	1.76PheSer: 1.76 ± 0.024	1.894PheThr: 1.894 ± 0.023	2.708PheVal: 2.708 ± 0.027	0.423PheTrp: 0.423 ± 0.011	0.713PheTyr: 0.713 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	11.768GlyAla: 11.768 ± 0.073	1.434GlyCys: 1.434 ± 0.029	5.421GlyAsp: 5.421 ± 0.043	4.98GlyGlu: 4.98 ± 0.04	2.958GlyPhe: 2.958 ± 0.028	9.072GlyGly: 9.072 ± 0.069	1.897GlyHis: 1.897 ± 0.024	3.513GlyIle: 3.513 ± 0.028	3.144GlyLys: 3.144 ± 0.034	7.318GlyLeu: 7.318 ± 0.044	1.863GlyMet: 1.863 ± 0.022	2.181GlyAsn: 2.181 ± 0.034	4.551GlyPro: 4.551 ± 0.039	2.369GlyGln: 2.369 ± 0.029	6.375GlyArg: 6.375 ± 0.046	5.57GlySer: 5.57 ± 0.046	5.599GlyThr: 5.599 ± 0.047	6.404GlyVal: 6.404 ± 0.041	1.188GlyTrp: 1.188 ± 0.019	1.985GlyTyr: 1.985 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	3.133HisAla: 3.133 ± 0.034	0.267HisCys: 0.267 ± 0.009	1.433HisAsp: 1.433 ± 0.018	1.374HisGlu: 1.374 ± 0.019	0.751HisPhe: 0.751 ± 0.016	2.171HisGly: 2.171 ± 0.025	0.659HisHis: 0.659 ± 0.013	0.646HisIle: 0.646 ± 0.013	0.407HisLys: 0.407 ± 0.008	2.125HisLeu: 2.125 ± 0.027	0.306HisMet: 0.306 ± 0.008	0.355HisAsn: 0.355 ± 0.009	1.496HisPro: 1.496 ± 0.018	0.51HisGln: 0.51 ± 0.011	1.922HisArg: 1.922 ± 0.023	0.707HisSer: 0.707 ± 0.013	0.96HisThr: 0.96 ± 0.016	1.95HisVal: 1.95 ± 0.021	0.302HisTrp: 0.302 ± 0.01	0.481HisTyr: 0.481 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	6.042IleAla: 6.042 ± 0.042	0.406IleCys: 0.406 ± 0.012	3.22IleAsp: 3.22 ± 0.028	2.986IleGlu: 2.986 ± 0.03	1.13IlePhe: 1.13 ± 0.016	3.649IleGly: 3.649 ± 0.031	0.951IleHis: 0.951 ± 0.015	1.147IleIle: 1.147 ± 0.017	0.98IleLys: 0.98 ± 0.017	3.146IleLeu: 3.146 ± 0.03	0.468IleMet: 0.468 ± 0.01	0.757IleAsn: 0.757 ± 0.014	2.125IlePro: 2.125 ± 0.023	0.947IleGln: 0.947 ± 0.014	2.407IleArg: 2.407 ± 0.028	1.894IleSer: 1.894 ± 0.022	2.283IleThr: 2.283 ± 0.023	3.506IleVal: 3.506 ± 0.026	0.376IleTrp: 0.376 ± 0.009	0.731IleTyr: 0.731 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.437LysAla: 3.437 ± 0.039	0.291LysCys: 0.291 ± 0.01	1.547LysAsp: 1.547 ± 0.024	1.397LysGlu: 1.397 ± 0.021	0.542LysPhe: 0.542 ± 0.012	2.298LysGly: 2.298 ± 0.029	0.597LysHis: 0.597 ± 0.011	1.212LysIle: 1.212 ± 0.023	1.432LysLys: 1.432 ± 0.027	2.963LysLeu: 2.963 ± 0.031	0.603LysMet: 0.603 ± 0.012	0.76LysAsn: 0.76 ± 0.014	2.071LysPro: 2.071 ± 0.026	0.87LysGln: 0.87 ± 0.016	2.186LysArg: 2.186 ± 0.025	1.506LysSer: 1.506 ± 0.02	1.596LysThr: 1.596 ± 0.021	2.086LysVal: 2.086 ± 0.023	0.286LysTrp: 0.286 ± 0.009	0.491LysTyr: 0.491 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	14.17LeuAla: 14.17 ± 0.077	1.053LeuCys: 1.053 ± 0.016	6.438LeuAsp: 6.438 ± 0.041	5.316LeuGlu: 5.316 ± 0.045	3.098LeuPhe: 3.098 ± 0.029	8.945LeuGly: 8.945 ± 0.054	2.113LeuHis: 2.113 ± 0.022	2.719LeuIle: 2.719 ± 0.029	2.121LeuLys: 2.121 ± 0.027	8.934LeuLeu: 8.934 ± 0.058	1.344LeuMet: 1.344 ± 0.018	1.435LeuAsn: 1.435 ± 0.019	5.726LeuPro: 5.726 ± 0.039	2.096LeuGln: 2.096 ± 0.023	8.109LeuArg: 8.109 ± 0.056	5.771LeuSer: 5.771 ± 0.042	4.904LeuThr: 4.904 ± 0.036	8.05LeuVal: 8.05 ± 0.044	1.145LeuTrp: 1.145 ± 0.016	1.75LeuTyr: 1.75 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.192MetAla: 2.192 ± 0.022	0.173MetCys: 0.173 ± 0.007	0.808MetAsp: 0.808 ± 0.013	0.842MetGlu: 0.842 ± 0.015	0.502MetPhe: 0.502 ± 0.011	1.54MetGly: 1.54 ± 0.022	0.404MetHis: 0.404 ± 0.01	0.849MetIle: 0.849 ± 0.015	0.749MetLys: 0.749 ± 0.014	1.908MetLeu: 1.908 ± 0.021	0.458MetMet: 0.458 ± 0.012	0.515MetAsn: 0.515 ± 0.012	1.269MetPro: 1.269 ± 0.017	0.481MetGln: 0.481 ± 0.012	1.684MetArg: 1.684 ± 0.022	1.373MetSer: 1.373 ± 0.017	1.186MetThr: 1.186 ± 0.015	1.297MetVal: 1.297 ± 0.017	0.194MetTrp: 0.194 ± 0.006	0.255MetTyr: 0.255 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.589AsnAla: 2.589 ± 0.028	0.293AsnCys: 0.293 ± 0.013	1.279AsnAsp: 1.279 ± 0.019	1.094AsnGlu: 1.094 ± 0.018	0.535AsnPhe: 0.535 ± 0.012	2.296AsnGly: 2.296 ± 0.043	0.45AsnHis: 0.45 ± 0.01	0.774AsnIle: 0.774 ± 0.014	0.533AsnLys: 0.533 ± 0.012	1.809AsnLeu: 1.809 ± 0.023	0.341AsnMet: 0.341 ± 0.009	0.558AsnAsn: 0.558 ± 0.014	1.394AsnPro: 1.394 ± 0.023	0.579AsnGln: 0.579 ± 0.013	1.196AsnArg: 1.196 ± 0.018	0.7AsnSer: 0.7 ± 0.013	1.055AsnThr: 1.055 ± 0.02	1.742AsnVal: 1.742 ± 0.021	0.211AsnTrp: 0.211 ± 0.006	0.411AsnTyr: 0.411 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	8.57ProAla: 8.57 ± 0.06	0.621ProCys: 0.621 ± 0.014	3.673ProAsp: 3.673 ± 0.03	4.063ProGlu: 4.063 ± 0.032	2.013ProPhe: 2.013 ± 0.023	5.182ProGly: 5.182 ± 0.041	1.187ProHis: 1.187 ± 0.016	2.519ProIle: 2.519 ± 0.027	1.87ProLys: 1.87 ± 0.022	5.209ProLeu: 5.209 ± 0.038	1.335ProMet: 1.335 ± 0.016	1.392ProAsn: 1.392 ± 0.019	5.462ProPro: 5.462 ± 0.067	1.472ProGln: 1.472 ± 0.026	4.549ProArg: 4.549 ± 0.039	4.603ProSer: 4.603 ± 0.039	3.346ProThr: 3.346 ± 0.029	4.237ProVal: 4.237 ± 0.036	0.826ProTrp: 0.826 ± 0.014	1.086ProTyr: 1.086 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.233GlnAla: 3.233 ± 0.03	0.388GlnCys: 0.388 ± 0.016	1.074GlnAsp: 1.074 ± 0.018	1.123GlnGlu: 1.123 ± 0.02	0.628GlnPhe: 0.628 ± 0.014	2.157GlnGly: 2.157 ± 0.025	0.626GlnHis: 0.626 ± 0.012	1.283GlnIle: 1.283 ± 0.019	0.99GlnLys: 0.99 ± 0.016	2.334GlnLeu: 2.334 ± 0.023	0.558GlnMet: 0.558 ± 0.01	0.657GlnAsn: 0.657 ± 0.014	1.573GlnPro: 1.573 ± 0.026	0.93GlnGln: 0.93 ± 0.022	2.387GlnArg: 2.387 ± 0.026	1.502GlnSer: 1.502 ± 0.02	1.391GlnThr: 1.391 ± 0.023	1.835GlnVal: 1.835 ± 0.022	0.347GlnTrp: 0.347 ± 0.008	0.508GlnTyr: 0.508 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	11.787ArgAla: 11.787 ± 0.092	0.915ArgCys: 0.915 ± 0.018	4.421ArgAsp: 4.421 ± 0.033	4.695ArgGlu: 4.695 ± 0.044	3.121ArgPhe: 3.121 ± 0.027	6.102ArgGly: 6.102 ± 0.042	1.728ArgHis: 1.728 ± 0.02	3.598ArgIle: 3.598 ± 0.032	1.817ArgLys: 1.817 ± 0.024	7.812ArgLeu: 7.812 ± 0.061	1.788ArgMet: 1.788 ± 0.017	1.208ArgAsn: 1.208 ± 0.017	4.224ArgPro: 4.224 ± 0.033	1.641ArgGln: 1.641 ± 0.019	7.673ArgArg: 7.673 ± 0.065	4.374ArgSer: 4.374 ± 0.03	3.836ArgThr: 3.836 ± 0.032	6.145ArgVal: 6.145 ± 0.043	1.292ArgTrp: 1.292 ± 0.016	1.759ArgTyr: 1.759 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	7.633SerAla: 7.633 ± 0.054	0.981SerCys: 0.981 ± 0.028	2.944SerAsp: 2.944 ± 0.027	2.574SerGlu: 2.574 ± 0.025	2.224SerPhe: 2.224 ± 0.023	5.767SerGly: 5.767 ± 0.051	1.042SerHis: 1.042 ± 0.016	2.54SerIle: 2.54 ± 0.022	1.452SerLys: 1.452 ± 0.023	5.315SerLeu: 5.315 ± 0.039	1.205SerMet: 1.205 ± 0.019	1.24SerAsn: 1.24 ± 0.019	3.864SerPro: 3.864 ± 0.034	1.287SerGln: 1.287 ± 0.018	3.955SerArg: 3.955 ± 0.031	4.676SerSer: 4.676 ± 0.075	3.547SerThr: 3.547 ± 0.033	3.967SerVal: 3.967 ± 0.028	0.76SerTrp: 0.76 ± 0.014	1.146SerTyr: 1.146 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	6.542ThrAla: 6.542 ± 0.045	1.037ThrCys: 1.037 ± 0.032	2.736ThrAsp: 2.736 ± 0.026	2.457ThrGlu: 2.457 ± 0.026	2.005ThrPhe: 2.005 ± 0.023	5.225ThrGly: 5.225 ± 0.047	1.082ThrHis: 1.082 ± 0.016	2.476ThrIle: 2.476 ± 0.023	1.497ThrLys: 1.497 ± 0.02	5.387ThrLeu: 5.387 ± 0.035	1.068ThrMet: 1.068 ± 0.014	1.221ThrAsn: 1.221 ± 0.019	3.898ThrPro: 3.898 ± 0.034	1.346ThrGln: 1.346 ± 0.017	3.635ThrArg: 3.635 ± 0.034	3.657ThrSer: 3.657 ± 0.032	3.542ThrThr: 3.542 ± 0.039	4.076ThrVal: 4.076 ± 0.032	0.851ThrTrp: 0.851 ± 0.014	1.177ThrTyr: 1.177 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	9.93ValAla: 9.93 ± 0.051	1.006ValCys: 1.006 ± 0.026	4.72ValAsp: 4.72 ± 0.036	4.635ValGlu: 4.635 ± 0.029	2.37ValPhe: 2.37 ± 0.023	5.821ValGly: 5.821 ± 0.047	1.696ValHis: 1.696 ± 0.022	3.206ValIle: 3.206 ± 0.027	2.038ValLys: 2.038 ± 0.025	7.604ValLeu: 7.604 ± 0.05	1.35ValMet: 1.35 ± 0.015	1.43ValAsn: 1.43 ± 0.023	4.587ValPro: 4.587 ± 0.037	1.9ValGln: 1.9 ± 0.021	6.119ValArg: 6.119 ± 0.042	4.457ValSer: 4.457 ± 0.035	4.569ValThr: 4.569 ± 0.034	6.673ValVal: 6.673 ± 0.051	0.963ValTrp: 0.963 ± 0.019	1.475ValTyr: 1.475 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.377TrpAla: 1.377 ± 0.019	0.156TrpCys: 0.156 ± 0.006	0.701TrpAsp: 0.701 ± 0.017	0.667TrpGlu: 0.667 ± 0.012	0.428TrpPhe: 0.428 ± 0.01	0.961TrpGly: 0.961 ± 0.019	0.29TrpHis: 0.29 ± 0.008	0.703TrpIle: 0.703 ± 0.013	0.422TrpLys: 0.422 ± 0.011	1.385TrpLeu: 1.385 ± 0.019	0.363TrpMet: 0.363 ± 0.01	0.364TrpAsn: 0.364 ± 0.009	0.664TrpPro: 0.664 ± 0.012	0.439TrpGln: 0.439 ± 0.01	0.928TrpArg: 0.928 ± 0.015	1.032TrpSer: 1.032 ± 0.017	0.79TrpThr: 0.79 ± 0.013	0.842TrpVal: 0.842 ± 0.014	0.202TrpTrp: 0.202 ± 0.007	0.255TrpTyr: 0.255 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.391TyrAla: 2.391 ± 0.023	0.257TyrCys: 0.257 ± 0.009	1.32TyrAsp: 1.32 ± 0.023	1.174TyrGlu: 1.174 ± 0.019	0.767TyrPhe: 0.767 ± 0.013	1.739TyrGly: 1.739 ± 0.021	0.427TyrHis: 0.427 ± 0.009	0.519TyrIle: 0.519 ± 0.01	0.465TyrLys: 0.465 ± 0.012	1.922TyrLeu: 1.922 ± 0.023	0.316TyrMet: 0.316 ± 0.009	0.43TyrAsn: 0.43 ± 0.011	1.042TyrPro: 1.042 ± 0.017	0.601TyrGln: 0.601 ± 0.012	1.669TyrArg: 1.669 ± 0.022	0.816TyrSer: 0.816 ± 0.016	0.984TyrThr: 0.984 ± 0.017	1.582TyrVal: 1.582 ± 0.024	0.298TyrTrp: 0.298 ± 0.008	0.517TyrTyr: 0.517 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13965 proteins (4652819 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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