Amino acid dipepetide frequency for Caballeronia glathei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.942AlaAla: 17.942 ± 0.153	1.366AlaCys: 1.366 ± 0.023	6.581AlaAsp: 6.581 ± 0.061	6.029AlaGlu: 6.029 ± 0.064	4.542AlaPhe: 4.542 ± 0.051	10.705AlaGly: 10.705 ± 0.091	2.863AlaHis: 2.863 ± 0.04	5.952AlaIle: 5.952 ± 0.053	3.857AlaLys: 3.857 ± 0.053	14.259AlaLeu: 14.259 ± 0.102	3.378AlaMet: 3.378 ± 0.037	3.251AlaAsn: 3.251 ± 0.045	6.014AlaPro: 6.014 ± 0.068	5.148AlaGln: 5.148 ± 0.054	9.485AlaArg: 9.485 ± 0.072	7.757AlaSer: 7.757 ± 0.075	6.317AlaThr: 6.317 ± 0.068	8.956AlaVal: 8.956 ± 0.071	1.656AlaTrp: 1.656 ± 0.03	2.714AlaTyr: 2.714 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	1.309CysAla: 1.309 ± 0.025	0.129CysCys: 0.129 ± 0.009	0.553CysAsp: 0.553 ± 0.019	0.502CysGlu: 0.502 ± 0.014	0.345CysPhe: 0.345 ± 0.012	1.019CysGly: 1.019 ± 0.021	0.252CysHis: 0.252 ± 0.012	0.427CysIle: 0.427 ± 0.015	0.201CysLys: 0.201 ± 0.01	0.77CysLeu: 0.77 ± 0.019	0.214CysMet: 0.214 ± 0.01	0.25CysAsn: 0.25 ± 0.011	0.44CysPro: 0.44 ± 0.015	0.203CysGln: 0.203 ± 0.011	0.641CysArg: 0.641 ± 0.02	0.518CysSer: 0.518 ± 0.013	0.482CysThr: 0.482 ± 0.014	0.815CysVal: 0.815 ± 0.019	0.115CysTrp: 0.115 ± 0.008	0.23CysTyr: 0.23 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.797AspAla: 7.797 ± 0.075	0.439AspCys: 0.439 ± 0.014	3.148AspAsp: 3.148 ± 0.047	3.423AspGlu: 3.423 ± 0.041	1.989AspPhe: 1.989 ± 0.028	4.543AspGly: 4.543 ± 0.049	1.157AspHis: 1.157 ± 0.024	2.624AspIle: 2.624 ± 0.039	1.492AspLys: 1.492 ± 0.028	5.104AspLeu: 5.104 ± 0.055	1.22AspMet: 1.22 ± 0.025	1.252AspAsn: 1.252 ± 0.023	3.024AspPro: 3.024 ± 0.04	1.468AspGln: 1.468 ± 0.023	3.48AspArg: 3.48 ± 0.043	2.408AspSer: 2.408 ± 0.031	2.738AspThr: 2.738 ± 0.037	4.346AspVal: 4.346 ± 0.047	0.86AspTrp: 0.86 ± 0.021	1.471AspTyr: 1.471 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.752GluAla: 6.752 ± 0.063	0.418GluCys: 0.418 ± 0.013	2.145GluAsp: 2.145 ± 0.031	2.508GluGlu: 2.508 ± 0.037	1.832GluPhe: 1.832 ± 0.028	3.585GluGly: 3.585 ± 0.04	1.462GluHis: 1.462 ± 0.028	2.745GluIle: 2.745 ± 0.039	1.814GluLys: 1.814 ± 0.03	5.432GluLeu: 5.432 ± 0.055	1.227GluMet: 1.227 ± 0.021	1.373GluAsn: 1.373 ± 0.024	2.595GluPro: 2.595 ± 0.042	2.201GluGln: 2.201 ± 0.036	5.151GluArg: 5.151 ± 0.055	2.76GluSer: 2.76 ± 0.041	2.902GluThr: 2.902 ± 0.036	3.501GluVal: 3.501 ± 0.045	0.734GluTrp: 0.734 ± 0.02	1.138GluTyr: 1.138 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	4.832PheAla: 4.832 ± 0.05	0.429PheCys: 0.429 ± 0.014	2.764PheAsp: 2.764 ± 0.039	2.137PheGlu: 2.137 ± 0.029	1.51PhePhe: 1.51 ± 0.029	3.815PheGly: 3.815 ± 0.051	0.778PheHis: 0.778 ± 0.017	1.665PheIle: 1.665 ± 0.027	0.968PheLys: 0.968 ± 0.02	3.09PheLeu: 3.09 ± 0.043	0.821PheMet: 0.821 ± 0.02	1.15PheAsn: 1.15 ± 0.023	1.589PhePro: 1.589 ± 0.029	0.977PheGln: 0.977 ± 0.021	2.162PheArg: 2.162 ± 0.031	2.329PheSer: 2.329 ± 0.034	2.006PheThr: 2.006 ± 0.028	3.218PheVal: 3.218 ± 0.035	0.51PheTrp: 0.51 ± 0.016	0.959PheTyr: 0.959 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	9.699GlyAla: 9.699 ± 0.078	0.886GlyCys: 0.886 ± 0.02	3.973GlyAsp: 3.973 ± 0.04	4.417GlyGlu: 4.417 ± 0.043	3.511GlyPhe: 3.511 ± 0.04	6.947GlyGly: 6.947 ± 0.103	1.862GlyHis: 1.862 ± 0.026	4.496GlyIle: 4.496 ± 0.049	3.092GlyLys: 3.092 ± 0.043	7.874GlyLeu: 7.874 ± 0.071	2.279GlyMet: 2.279 ± 0.036	2.248GlyAsn: 2.248 ± 0.04	3.018GlyPro: 3.018 ± 0.041	2.633GlyGln: 2.633 ± 0.035	5.626GlyArg: 5.626 ± 0.049	4.596GlySer: 4.596 ± 0.044	4.654GlyThr: 4.654 ± 0.051	6.793GlyVal: 6.793 ± 0.057	1.395GlyTrp: 1.395 ± 0.026	2.378GlyTyr: 2.378 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	3.164HisAla: 3.164 ± 0.036	0.27HisCys: 0.27 ± 0.012	1.366HisAsp: 1.366 ± 0.026	1.253HisGlu: 1.253 ± 0.025	0.943HisPhe: 0.943 ± 0.022	2.172HisGly: 2.172 ± 0.032	0.621HisHis: 0.621 ± 0.02	0.92HisIle: 0.92 ± 0.021	0.507HisLys: 0.507 ± 0.013	2.143HisLeu: 2.143 ± 0.029	0.503HisMet: 0.503 ± 0.015	0.485HisAsn: 0.485 ± 0.015	1.408HisPro: 1.408 ± 0.025	0.641HisGln: 0.641 ± 0.018	1.571HisArg: 1.571 ± 0.029	1.098HisSer: 1.098 ± 0.023	1.057HisThr: 1.057 ± 0.021	1.809HisVal: 1.809 ± 0.029	0.388HisTrp: 0.388 ± 0.012	0.64HisTyr: 0.64 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	7.226IleAla: 7.226 ± 0.055	0.46IleCys: 0.46 ± 0.015	3.552IleAsp: 3.552 ± 0.039	3.332IleGlu: 3.332 ± 0.043	1.544IlePhe: 1.544 ± 0.027	4.962IleGly: 4.962 ± 0.056	0.914IleHis: 0.914 ± 0.019	1.667IleIle: 1.667 ± 0.031	1.292IleLys: 1.292 ± 0.024	3.486IleLeu: 3.486 ± 0.044	0.776IleMet: 0.776 ± 0.018	1.353IleAsn: 1.353 ± 0.025	2.115IlePro: 2.115 ± 0.032	1.2IleGln: 1.2 ± 0.024	2.944IleArg: 2.944 ± 0.035	2.474IleSer: 2.474 ± 0.032	2.344IleThr: 2.344 ± 0.034	4.535IleVal: 4.535 ± 0.059	0.505IleTrp: 0.505 ± 0.016	1.094IleTyr: 1.094 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.657LysAla: 3.657 ± 0.048	0.182LysCys: 0.182 ± 0.01	1.462LysAsp: 1.462 ± 0.028	1.526LysGlu: 1.526 ± 0.03	0.893LysPhe: 0.893 ± 0.021	2.217LysGly: 2.217 ± 0.035	0.701LysHis: 0.701 ± 0.018	1.546LysIle: 1.546 ± 0.03	1.328LysLys: 1.328 ± 0.031	3.251LysLeu: 3.251 ± 0.036	0.787LysMet: 0.787 ± 0.018	0.854LysAsn: 0.854 ± 0.022	1.973LysPro: 1.973 ± 0.031	1.177LysGln: 1.177 ± 0.027	2.391LysArg: 2.391 ± 0.037	1.806LysSer: 1.806 ± 0.031	1.834LysThr: 1.834 ± 0.033	2.289LysVal: 2.289 ± 0.034	0.419LysTrp: 0.419 ± 0.014	0.699LysTyr: 0.699 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	14.114LeuAla: 14.114 ± 0.096	1.021LeuCys: 1.021 ± 0.02	5.951LeuAsp: 5.951 ± 0.058	4.964LeuGlu: 4.964 ± 0.05	3.677LeuPhe: 3.677 ± 0.044	8.094LeuGly: 8.094 ± 0.07	2.203LeuHis: 2.203 ± 0.032	4.647LeuIle: 4.647 ± 0.053	3.244LeuLys: 3.244 ± 0.046	9.745LeuLeu: 9.745 ± 0.087	2.288LeuMet: 2.288 ± 0.035	2.642LeuAsn: 2.642 ± 0.032	5.593LeuPro: 5.593 ± 0.052	3.16LeuGln: 3.16 ± 0.035	7.083LeuArg: 7.083 ± 0.068	6.185LeuSer: 6.185 ± 0.059	5.426LeuThr: 5.426 ± 0.056	7.64LeuVal: 7.64 ± 0.059	1.101LeuTrp: 1.101 ± 0.024	2.086LeuTyr: 2.086 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.524MetAla: 2.524 ± 0.034	0.193MetCys: 0.193 ± 0.01	0.927MetAsp: 0.927 ± 0.024	0.934MetGlu: 0.934 ± 0.019	0.818MetPhe: 0.818 ± 0.021	1.516MetGly: 1.516 ± 0.029	0.586MetHis: 0.586 ± 0.015	1.177MetIle: 1.177 ± 0.023	1.093MetLys: 1.093 ± 0.024	2.759MetLeu: 2.759 ± 0.036	0.617MetMet: 0.617 ± 0.017	0.979MetAsn: 0.979 ± 0.021	1.5MetPro: 1.5 ± 0.026	1.011MetGln: 1.011 ± 0.02	1.883MetArg: 1.883 ± 0.027	1.829MetSer: 1.829 ± 0.028	1.685MetThr: 1.685 ± 0.027	1.496MetVal: 1.496 ± 0.026	0.229MetTrp: 0.229 ± 0.009	0.403MetTyr: 0.403 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.554AsnAla: 3.554 ± 0.05	0.263AsnCys: 0.263 ± 0.01	1.435AsnAsp: 1.435 ± 0.029	1.324AsnGlu: 1.324 ± 0.023	1.002AsnPhe: 1.002 ± 0.02	2.492AsnGly: 2.492 ± 0.042	0.538AsnHis: 0.538 ± 0.017	1.199AsnIle: 1.199 ± 0.023	0.678AsnLys: 0.678 ± 0.019	2.627AsnLeu: 2.627 ± 0.035	0.575AsnMet: 0.575 ± 0.015	0.8AsnAsn: 0.8 ± 0.024	1.757AsnPro: 1.757 ± 0.031	0.887AsnGln: 0.887 ± 0.021	1.815AsnArg: 1.815 ± 0.032	1.321AsnSer: 1.321 ± 0.029	1.45AsnThr: 1.45 ± 0.026	2.254AsnVal: 2.254 ± 0.029	0.418AsnTrp: 0.418 ± 0.014	0.723AsnTyr: 0.723 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.795ProAla: 6.795 ± 0.07	0.35ProCys: 0.35 ± 0.012	3.233ProAsp: 3.233 ± 0.037	3.058ProGlu: 3.058 ± 0.042	2.0ProPhe: 2.0 ± 0.029	4.392ProGly: 4.392 ± 0.053	1.227ProHis: 1.227 ± 0.024	1.998ProIle: 1.998 ± 0.031	1.496ProLys: 1.496 ± 0.027	5.096ProLeu: 5.096 ± 0.051	1.153ProMet: 1.153 ± 0.023	1.369ProAsn: 1.369 ± 0.026	2.566ProPro: 2.566 ± 0.041	1.797ProGln: 1.797 ± 0.031	2.924ProArg: 2.924 ± 0.038	2.899ProSer: 2.899 ± 0.039	2.385ProThr: 2.385 ± 0.033	4.347ProVal: 4.347 ± 0.038	0.666ProTrp: 0.666 ± 0.017	1.232ProTyr: 1.232 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	4.241GlnAla: 4.241 ± 0.048	0.274GlnCys: 0.274 ± 0.011	1.279GlnAsp: 1.279 ± 0.025	1.383GlnGlu: 1.383 ± 0.026	1.266GlnPhe: 1.266 ± 0.025	2.333GlnGly: 2.333 ± 0.032	0.851GlnHis: 0.851 ± 0.022	1.859GlnIle: 1.859 ± 0.03	1.156GlnLys: 1.156 ± 0.025	3.555GlnLeu: 3.555 ± 0.04	0.983GlnMet: 0.983 ± 0.023	0.927GlnAsn: 0.927 ± 0.021	1.928GlnPro: 1.928 ± 0.033	1.636GlnGln: 1.636 ± 0.035	2.681GlnArg: 2.681 ± 0.038	1.962GlnSer: 1.962 ± 0.03	1.959GlnThr: 1.959 ± 0.03	2.412GlnVal: 2.412 ± 0.038	0.535GlnTrp: 0.535 ± 0.016	0.875GlnTyr: 0.875 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.637ArgAla: 8.637 ± 0.065	0.594ArgCys: 0.594 ± 0.017	3.918ArgAsp: 3.918 ± 0.043	4.481ArgGlu: 4.481 ± 0.046	3.017ArgPhe: 3.017 ± 0.038	4.778ArgGly: 4.778 ± 0.046	1.92ArgHis: 1.92 ± 0.033	3.812ArgIle: 3.812 ± 0.042	2.112ArgLys: 2.112 ± 0.037	7.334ArgLeu: 7.334 ± 0.07	1.913ArgMet: 1.913 ± 0.029	1.894ArgAsn: 1.894 ± 0.028	3.169ArgPro: 3.169 ± 0.04	2.44ArgGln: 2.44 ± 0.037	5.612ArgArg: 5.612 ± 0.063	3.652ArgSer: 3.652 ± 0.042	3.539ArgThr: 3.539 ± 0.034	5.526ArgVal: 5.526 ± 0.048	1.068ArgTrp: 1.068 ± 0.025	1.907ArgTyr: 1.907 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.97SerAla: 6.97 ± 0.065	0.452SerCys: 0.452 ± 0.016	2.867SerAsp: 2.867 ± 0.035	2.667SerGlu: 2.667 ± 0.036	2.258SerPhe: 2.258 ± 0.028	5.428SerGly: 5.428 ± 0.051	1.264SerHis: 1.264 ± 0.025	2.858SerIle: 2.858 ± 0.035	1.688SerLys: 1.688 ± 0.03	5.736SerLeu: 5.736 ± 0.057	1.488SerMet: 1.488 ± 0.025	1.637SerAsn: 1.637 ± 0.03	2.885SerPro: 2.885 ± 0.04	1.824SerGln: 1.824 ± 0.028	3.84SerArg: 3.84 ± 0.043	3.277SerSer: 3.277 ± 0.048	3.049SerThr: 3.049 ± 0.04	4.523SerVal: 4.523 ± 0.049	0.675SerTrp: 0.675 ± 0.019	1.284SerTyr: 1.284 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.882ThrAla: 5.882 ± 0.052	0.423ThrCys: 0.423 ± 0.014	2.65ThrAsp: 2.65 ± 0.04	2.264ThrGlu: 2.264 ± 0.03	2.024ThrPhe: 2.024 ± 0.031	4.788ThrGly: 4.788 ± 0.056	1.283ThrHis: 1.283 ± 0.025	2.636ThrIle: 2.636 ± 0.044	1.397ThrLys: 1.397 ± 0.028	6.285ThrLeu: 6.285 ± 0.058	1.216ThrMet: 1.216 ± 0.02	1.363ThrAsn: 1.363 ± 0.024	3.468ThrPro: 3.468 ± 0.043	1.843ThrGln: 1.843 ± 0.029	3.583ThrArg: 3.583 ± 0.041	2.959ThrSer: 2.959 ± 0.037	2.848ThrThr: 2.848 ± 0.04	4.411ThrVal: 4.411 ± 0.046	0.671ThrTrp: 0.671 ± 0.017	1.232ThrTyr: 1.232 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	9.785ValAla: 9.785 ± 0.079	0.868ValCys: 0.868 ± 0.02	4.251ValAsp: 4.251 ± 0.048	4.324ValGlu: 4.324 ± 0.046	2.957ValPhe: 2.957 ± 0.035	5.53ValGly: 5.53 ± 0.056	1.588ValHis: 1.588 ± 0.027	3.958ValIle: 3.958 ± 0.049	2.509ValLys: 2.509 ± 0.037	7.969ValLeu: 7.969 ± 0.067	1.896ValMet: 1.896 ± 0.027	2.227ValAsn: 2.227 ± 0.032	4.066ValPro: 4.066 ± 0.044	2.406ValGln: 2.406 ± 0.029	5.344ValArg: 5.344 ± 0.051	4.753ValSer: 4.753 ± 0.047	4.569ValThr: 4.569 ± 0.045	6.45ValVal: 6.45 ± 0.059	0.963ValTrp: 0.963 ± 0.018	1.689ValTyr: 1.689 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.151TrpAla: 1.151 ± 0.024	0.144TrpCys: 0.144 ± 0.007	0.614TrpAsp: 0.614 ± 0.017	0.519TrpGlu: 0.519 ± 0.017	0.55TrpPhe: 0.55 ± 0.016	0.89TrpGly: 0.89 ± 0.021	0.4TrpHis: 0.4 ± 0.012	0.715TrpIle: 0.715 ± 0.021	0.45TrpLys: 0.45 ± 0.014	1.85TrpLeu: 1.85 ± 0.031	0.37TrpMet: 0.37 ± 0.013	0.454TrpAsn: 0.454 ± 0.015	0.636TrpPro: 0.636 ± 0.017	0.622TrpGln: 0.622 ± 0.016	1.19TrpArg: 1.19 ± 0.025	0.802TrpSer: 0.802 ± 0.019	0.747TrpThr: 0.747 ± 0.016	0.886TrpVal: 0.886 ± 0.02	0.217TrpTrp: 0.217 ± 0.008	0.301TrpTyr: 0.301 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.74TyrAla: 2.74 ± 0.034	0.254TyrCys: 0.254 ± 0.011	1.31TyrAsp: 1.31 ± 0.027	1.231TyrGlu: 1.231 ± 0.025	1.031TyrPhe: 1.031 ± 0.022	2.175TyrGly: 2.175 ± 0.032	0.488TyrHis: 0.488 ± 0.013	0.874TyrIle: 0.874 ± 0.022	0.619TyrLys: 0.619 ± 0.018	2.5TyrLeu: 2.5 ± 0.039	0.454TyrMet: 0.454 ± 0.012	0.606TyrAsn: 0.606 ± 0.018	1.239TyrPro: 1.239 ± 0.024	0.821TyrGln: 0.821 ± 0.021	1.919TyrArg: 1.919 ± 0.033	1.286TyrSer: 1.286 ± 0.027	1.233TyrThr: 1.233 ± 0.027	1.892TyrVal: 1.892 ± 0.026	0.382TyrTrp: 0.382 ± 0.014	0.642TyrTyr: 0.642 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7464 proteins (2290966 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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