Amino acid dipepetide frequency for Hubei diptera virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.054AlaAla: 1.054 ± 0.787
2.107AlaCys: 2.107 ± 1.116
1.054AlaAsp: 1.054 ± 0.787
1.054AlaGlu: 1.054 ± 0.558
3.161AlaPhe: 3.161 ± 0.328
2.107AlaGly: 2.107 ± 0.23
2.107AlaHis: 2.107 ± 0.23
3.161AlaIle: 3.161 ± 0.328
4.215AlaLys: 4.215 ± 0.886
7.376AlaLeu: 7.376 ± 0.131
2.107AlaMet: 2.107 ± 1.116
1.054AlaAsn: 1.054 ± 0.787
3.161AlaPro: 3.161 ± 0.328
2.107AlaGln: 2.107 ± 1.116
3.161AlaArg: 3.161 ± 1.017
6.322AlaSer: 6.322 ± 3.347
6.322AlaThr: 6.322 ± 2.001
2.107AlaVal: 2.107 ± 1.116
0.0AlaTrp: 0.0 ± 0.0
3.161AlaTyr: 3.161 ± 0.328
0.0AlaXaa: 0.0 ± 0.0
Cys
1.054CysAla: 1.054 ± 0.558
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.054CysGlu: 1.054 ± 0.558
1.054CysPhe: 1.054 ± 0.787
1.054CysGly: 1.054 ± 0.787
1.054CysHis: 1.054 ± 0.787
2.107CysIle: 2.107 ± 1.116
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.57
0.0CysAsn: 0.0 ± 0.0
1.054CysPro: 1.054 ± 0.787
1.054CysGln: 1.054 ± 0.558
2.107CysArg: 2.107 ± 1.575
0.0CysSer: 0.0 ± 0.0
1.054CysThr: 1.054 ± 0.787
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
3.161CysTyr: 3.161 ± 0.328
0.0CysXaa: 0.0 ± 0.0
Asp
2.107AspAla: 2.107 ± 1.575
2.107AspCys: 2.107 ± 0.23
2.107AspAsp: 2.107 ± 0.23
2.107AspGlu: 2.107 ± 0.23
1.054AspPhe: 1.054 ± 0.558
3.161AspGly: 3.161 ± 1.017
2.107AspHis: 2.107 ± 0.23
0.0AspIle: 0.0 ± 0.0
1.054AspLys: 1.054 ± 0.558
4.215AspLeu: 4.215 ± 0.886
1.054AspMet: 1.054 ± 0.787
1.054AspAsn: 1.054 ± 0.787
1.054AspPro: 1.054 ± 0.787
3.161AspGln: 3.161 ± 0.328
1.054AspArg: 1.054 ± 0.787
3.161AspSer: 3.161 ± 0.328
4.215AspThr: 4.215 ± 1.804
4.215AspVal: 4.215 ± 0.459
0.0AspTrp: 0.0 ± 0.0
7.376AspTyr: 7.376 ± 2.821
0.0AspXaa: 0.0 ± 0.0
Glu
2.107GluAla: 2.107 ± 1.575
0.0GluCys: 0.0 ± 0.0
3.161GluAsp: 3.161 ± 0.328
2.107GluGlu: 2.107 ± 1.116
1.054GluPhe: 1.054 ± 0.787
3.161GluGly: 3.161 ± 0.328
1.054GluHis: 1.054 ± 0.558
3.161GluIle: 3.161 ± 0.328
1.054GluLys: 1.054 ± 0.787
6.322GluLeu: 6.322 ± 2.001
1.054GluMet: 1.054 ± 0.787
0.0GluAsn: 0.0 ± 0.0
2.107GluPro: 2.107 ± 1.116
2.107GluGln: 2.107 ± 1.116
3.161GluArg: 3.161 ± 2.362
5.269GluSer: 5.269 ± 0.099
3.161GluThr: 3.161 ± 1.673
1.054GluVal: 1.054 ± 0.558
0.0GluTrp: 0.0 ± 0.0
2.107GluTyr: 2.107 ± 0.23
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.054PheCys: 1.054 ± 0.787
2.107PheAsp: 2.107 ± 1.575
1.054PheGlu: 1.054 ± 0.787
1.054PhePhe: 1.054 ± 0.558
3.161PheGly: 3.161 ± 1.017
1.054PheHis: 1.054 ± 0.558
2.107PheIle: 2.107 ± 0.23
2.107PheLys: 2.107 ± 0.23
3.161PheLeu: 3.161 ± 1.673
0.0PheMet: 0.0 ± 0.0
4.215PheAsn: 4.215 ± 1.804
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
3.161PheArg: 3.161 ± 1.017
1.054PheSer: 1.054 ± 0.558
5.269PheThr: 5.269 ± 0.099
2.107PheVal: 2.107 ± 1.116
0.0PheTrp: 0.0 ± 0.0
3.161PheTyr: 3.161 ± 2.362
0.0PheXaa: 0.0 ± 0.0
Gly
3.161GlyAla: 3.161 ± 0.328
2.107GlyCys: 2.107 ± 1.575
5.269GlyAsp: 5.269 ± 2.592
2.107GlyGlu: 2.107 ± 0.23
1.054GlyPhe: 1.054 ± 0.787
0.0GlyGly: 0.0 ± 0.0
1.054GlyHis: 1.054 ± 0.787
1.054GlyIle: 1.054 ± 0.558
3.161GlyLys: 3.161 ± 1.017
2.107GlyLeu: 2.107 ± 1.116
1.054GlyMet: 1.054 ± 0.558
1.054GlyAsn: 1.054 ± 0.787
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
1.054GlyArg: 1.054 ± 0.787
3.161GlySer: 3.161 ± 0.328
3.161GlyThr: 3.161 ± 2.362
0.0GlyVal: 0.0 ± 0.0
1.054GlyTrp: 1.054 ± 0.558
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.107HisAla: 2.107 ± 0.23
0.0HisCys: 0.0 ± 0.0
1.054HisAsp: 1.054 ± 0.558
1.054HisGlu: 1.054 ± 0.558
0.0HisPhe: 0.0 ± 0.0
1.054HisGly: 1.054 ± 0.558
1.054HisHis: 1.054 ± 0.787
1.054HisIle: 1.054 ± 0.558
1.054HisLys: 1.054 ± 0.558
6.322HisLeu: 6.322 ± 0.656
0.0HisMet: 0.0 ± 0.0
1.054HisAsn: 1.054 ± 0.787
3.161HisPro: 3.161 ± 2.362
1.054HisGln: 1.054 ± 0.558
1.054HisArg: 1.054 ± 0.787
3.161HisSer: 3.161 ± 1.673
4.215HisThr: 4.215 ± 0.459
1.054HisVal: 1.054 ± 0.787
0.0HisTrp: 0.0 ± 0.0
1.054HisTyr: 1.054 ± 0.558
0.0HisXaa: 0.0 ± 0.0
Ile
1.054IleAla: 1.054 ± 0.558
0.0IleCys: 0.0 ± 0.0
2.107IleAsp: 2.107 ± 0.23
5.269IleGlu: 5.269 ± 1.247
2.107IlePhe: 2.107 ± 0.23
1.054IleGly: 1.054 ± 0.787
5.269IleHis: 5.269 ± 1.247
8.43IleIle: 8.43 ± 0.919
3.161IleLys: 3.161 ± 1.017
3.161IleLeu: 3.161 ± 0.328
4.215IleMet: 4.215 ± 0.886
8.43IleAsn: 8.43 ± 0.919
3.161IlePro: 3.161 ± 1.673
3.161IleGln: 3.161 ± 0.328
3.161IleArg: 3.161 ± 1.017
5.269IleSer: 5.269 ± 0.099
5.269IleThr: 5.269 ± 1.444
3.161IleVal: 3.161 ± 0.328
1.054IleTrp: 1.054 ± 0.558
3.161IleTyr: 3.161 ± 0.328
0.0IleXaa: 0.0 ± 0.0
Lys
2.107LysAla: 2.107 ± 0.23
2.107LysCys: 2.107 ± 0.23
0.0LysAsp: 0.0 ± 0.0
4.215LysGlu: 4.215 ± 0.886
2.107LysPhe: 2.107 ± 0.23
1.054LysGly: 1.054 ± 0.787
0.0LysHis: 0.0 ± 0.0
2.107LysIle: 2.107 ± 0.23
4.215LysLys: 4.215 ± 0.459
10.537LysLeu: 10.537 ± 3.839
2.107LysMet: 2.107 ± 0.23
0.0LysAsn: 0.0 ± 0.0
8.43LysPro: 8.43 ± 2.264
2.107LysGln: 2.107 ± 0.23
2.107LysArg: 2.107 ± 0.23
0.0LysSer: 0.0 ± 0.0
6.322LysThr: 6.322 ± 2.001
4.215LysVal: 4.215 ± 0.459
1.054LysTrp: 1.054 ± 0.558
5.269LysTyr: 5.269 ± 2.592
0.0LysXaa: 0.0 ± 0.0
Leu
8.43LeuAla: 8.43 ± 1.772
2.107LeuCys: 2.107 ± 1.575
3.161LeuAsp: 3.161 ± 1.017
8.43LeuGlu: 8.43 ± 2.264
5.269LeuPhe: 5.269 ± 1.444
3.161LeuGly: 3.161 ± 0.328
4.215LeuHis: 4.215 ± 0.886
6.322LeuIle: 6.322 ± 0.656
4.215LeuLys: 4.215 ± 1.804
5.269LeuLeu: 5.269 ± 0.099
3.161LeuMet: 3.161 ± 1.673
3.161LeuAsn: 3.161 ± 1.673
6.322LeuPro: 6.322 ± 0.656
4.215LeuGln: 4.215 ± 2.231
7.376LeuArg: 7.376 ± 1.476
11.591LeuSer: 11.591 ± 0.755
8.43LeuThr: 8.43 ± 1.772
1.054LeuVal: 1.054 ± 0.558
2.107LeuTrp: 2.107 ± 1.116
2.107LeuTyr: 2.107 ± 0.23
0.0LeuXaa: 0.0 ± 0.0
Met
3.161MetAla: 3.161 ± 1.673
0.0MetCys: 0.0 ± 0.0
2.107MetAsp: 2.107 ± 1.575
3.161MetGlu: 3.161 ± 0.328
0.0MetPhe: 0.0 ± 0.0
2.107MetGly: 2.107 ± 1.575
1.054MetHis: 1.054 ± 0.558
1.054MetIle: 1.054 ± 0.787
1.054MetLys: 1.054 ± 0.558
2.107MetLeu: 2.107 ± 1.575
0.0MetMet: 0.0 ± 0.0
3.161MetAsn: 3.161 ± 1.673
1.054MetPro: 1.054 ± 0.558
2.107MetGln: 2.107 ± 0.23
0.0MetArg: 0.0 ± 0.0
2.107MetSer: 2.107 ± 0.23
3.161MetThr: 3.161 ± 0.328
2.107MetVal: 2.107 ± 1.116
0.0MetTrp: 0.0 ± 0.0
1.054MetTyr: 1.054 ± 0.787
0.0MetXaa: 0.0 ± 0.0
Asn
4.215AsnAla: 4.215 ± 2.231
0.0AsnCys: 0.0 ± 0.0
2.107AsnAsp: 2.107 ± 0.23
0.0AsnGlu: 0.0 ± 0.0
1.054AsnPhe: 1.054 ± 0.787
3.161AsnGly: 3.161 ± 2.362
2.107AsnHis: 2.107 ± 0.23
8.43AsnIle: 8.43 ± 2.264
4.215AsnLys: 4.215 ± 1.804
3.161AsnLeu: 3.161 ± 0.328
1.054AsnMet: 1.054 ± 0.787
1.054AsnAsn: 1.054 ± 0.787
0.0AsnPro: 0.0 ± 0.0
0.0AsnGln: 0.0 ± 0.0
2.107AsnArg: 2.107 ± 1.575
4.215AsnSer: 4.215 ± 0.459
1.054AsnThr: 1.054 ± 0.558
0.0AsnVal: 0.0 ± 0.0
1.054AsnTrp: 1.054 ± 0.787
5.269AsnTyr: 5.269 ± 0.099
0.0AsnXaa: 0.0 ± 0.0
Pro
1.054ProAla: 1.054 ± 0.558
0.0ProCys: 0.0 ± 0.0
2.107ProAsp: 2.107 ± 1.575
1.054ProGlu: 1.054 ± 0.558
3.161ProPhe: 3.161 ± 1.017
1.054ProGly: 1.054 ± 0.558
1.054ProHis: 1.054 ± 0.558
4.215ProIle: 4.215 ± 1.804
4.215ProLys: 4.215 ± 0.459
6.322ProLeu: 6.322 ± 0.656
1.054ProMet: 1.054 ± 0.558
0.0ProAsn: 0.0 ± 0.0
6.322ProPro: 6.322 ± 2.001
2.107ProGln: 2.107 ± 1.116
1.054ProArg: 1.054 ± 0.787
9.484ProSer: 9.484 ± 0.984
3.161ProThr: 3.161 ± 1.017
1.054ProVal: 1.054 ± 0.787
1.054ProTrp: 1.054 ± 0.787
3.161ProTyr: 3.161 ± 0.328
0.0ProXaa: 0.0 ± 0.0
Gln
1.054GlnAla: 1.054 ± 0.787
1.054GlnCys: 1.054 ± 0.787
1.054GlnAsp: 1.054 ± 0.558
0.0GlnGlu: 0.0 ± 0.0
1.054GlnPhe: 1.054 ± 0.787
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
3.161GlnIle: 3.161 ± 0.328
0.0GlnLys: 0.0 ± 0.0
4.215GlnLeu: 4.215 ± 0.886
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
6.322GlnPro: 6.322 ± 2.001
3.161GlnGln: 3.161 ± 1.673
2.107GlnArg: 2.107 ± 1.116
4.215GlnSer: 4.215 ± 2.231
3.161GlnThr: 3.161 ± 1.673
3.161GlnVal: 3.161 ± 1.673
0.0GlnTrp: 0.0 ± 0.0
3.161GlnTyr: 3.161 ± 0.328
0.0GlnXaa: 0.0 ± 0.0
Arg
4.215ArgAla: 4.215 ± 0.459
2.107ArgCys: 2.107 ± 0.23
1.054ArgAsp: 1.054 ± 0.787
2.107ArgGlu: 2.107 ± 1.116
2.107ArgPhe: 2.107 ± 1.575
0.0ArgGly: 0.0 ± 0.0
1.054ArgHis: 1.054 ± 0.787
1.054ArgIle: 1.054 ± 0.787
5.269ArgLys: 5.269 ± 0.099
6.322ArgLeu: 6.322 ± 3.379
1.054ArgMet: 1.054 ± 0.787
2.107ArgAsn: 2.107 ± 1.575
1.054ArgPro: 1.054 ± 0.558
2.107ArgGln: 2.107 ± 0.23
3.161ArgArg: 3.161 ± 1.017
3.161ArgSer: 3.161 ± 1.017
3.161ArgThr: 3.161 ± 1.017
3.161ArgVal: 3.161 ± 1.017
3.161ArgTrp: 3.161 ± 1.673
2.107ArgTyr: 2.107 ± 1.575
0.0ArgXaa: 0.0 ± 0.0
Ser
5.269SerAla: 5.269 ± 1.444
0.0SerCys: 0.0 ± 0.0
1.054SerAsp: 1.054 ± 0.558
0.0SerGlu: 0.0 ± 0.0
4.215SerPhe: 4.215 ± 0.459
4.215SerGly: 4.215 ± 0.459
1.054SerHis: 1.054 ± 0.558
7.376SerIle: 7.376 ± 2.559
5.269SerLys: 5.269 ± 1.247
9.484SerLeu: 9.484 ± 3.675
5.269SerMet: 5.269 ± 1.444
5.269SerAsn: 5.269 ± 1.247
1.054SerPro: 1.054 ± 0.787
3.161SerGln: 3.161 ± 0.328
4.215SerArg: 4.215 ± 0.459
7.376SerSer: 7.376 ± 1.214
6.322SerThr: 6.322 ± 3.347
6.322SerVal: 6.322 ± 2.001
1.054SerTrp: 1.054 ± 0.558
4.215SerTyr: 4.215 ± 0.459
0.0SerXaa: 0.0 ± 0.0
Thr
6.322ThrAla: 6.322 ± 2.001
1.054ThrCys: 1.054 ± 0.558
3.161ThrAsp: 3.161 ± 0.328
3.161ThrGlu: 3.161 ± 0.328
3.161ThrPhe: 3.161 ± 1.017
0.0ThrGly: 0.0 ± 0.0
2.107ThrHis: 2.107 ± 1.116
4.215ThrIle: 4.215 ± 0.459
9.484ThrLys: 9.484 ± 1.706
5.269ThrLeu: 5.269 ± 2.789
2.107ThrMet: 2.107 ± 0.654
3.161ThrAsn: 3.161 ± 2.362
5.269ThrPro: 5.269 ± 0.099
1.054ThrGln: 1.054 ± 0.558
6.322ThrArg: 6.322 ± 0.656
8.43ThrSer: 8.43 ± 3.117
13.699ThrThr: 13.699 ± 5.906
5.269ThrVal: 5.269 ± 1.247
3.161ThrTrp: 3.161 ± 1.673
4.215ThrTyr: 4.215 ± 0.886
0.0ThrXaa: 0.0 ± 0.0
Val
4.215ValAla: 4.215 ± 0.886
0.0ValCys: 0.0 ± 0.0
2.107ValAsp: 2.107 ± 0.23
3.161ValGlu: 3.161 ± 0.328
1.054ValPhe: 1.054 ± 0.787
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
3.161ValIle: 3.161 ± 1.673
1.054ValLys: 1.054 ± 0.558
6.322ValLeu: 6.322 ± 2.001
0.0ValMet: 0.0 ± 0.0
4.215ValAsn: 4.215 ± 1.804
1.054ValPro: 1.054 ± 0.787
3.161ValGln: 3.161 ± 0.328
3.161ValArg: 3.161 ± 0.328
2.107ValSer: 2.107 ± 0.23
6.322ValThr: 6.322 ± 2.001
4.215ValVal: 4.215 ± 2.231
0.0ValTrp: 0.0 ± 0.0
2.107ValTyr: 2.107 ± 0.23
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.054TrpAsp: 1.054 ± 0.558
1.054TrpGlu: 1.054 ± 0.558
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.054TrpHis: 1.054 ± 0.558
4.215TrpIle: 4.215 ± 2.231
3.161TrpLys: 3.161 ± 0.328
1.054TrpLeu: 1.054 ± 0.558
1.054TrpMet: 1.054 ± 0.558
1.054TrpAsn: 1.054 ± 0.558
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.054TrpSer: 1.054 ± 0.787
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.215TyrAla: 4.215 ± 2.231
1.054TyrCys: 1.054 ± 0.558
10.537TyrAsp: 10.537 ± 1.148
1.054TyrGlu: 1.054 ± 0.558
2.107TyrPhe: 2.107 ± 1.116
2.107TyrGly: 2.107 ± 0.23
2.107TyrHis: 2.107 ± 0.23
5.269TyrIle: 5.269 ± 3.937
2.107TyrLys: 2.107 ± 1.575
7.376TyrLeu: 7.376 ± 1.476
3.161TyrMet: 3.161 ± 2.362
4.215TyrAsn: 4.215 ± 0.886
2.107TyrPro: 2.107 ± 1.575
1.054TyrGln: 1.054 ± 0.558
0.0TyrArg: 0.0 ± 0.0
1.054TyrSer: 1.054 ± 0.558
3.161TyrThr: 3.161 ± 2.362
3.161TyrVal: 3.161 ± 0.328
0.0TyrTrp: 0.0 ± 0.0
3.161TyrTyr: 3.161 ± 1.017
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (950 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski