Amino acid dipepetide frequency for Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5) (Clostridium lentocellum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.947AlaAla: 4.947 ± 0.097	0.859AlaCys: 0.859 ± 0.026	3.163AlaAsp: 3.163 ± 0.049	4.363AlaGlu: 4.363 ± 0.07	3.043AlaPhe: 3.043 ± 0.055	4.377AlaGly: 4.377 ± 0.072	1.195AlaHis: 1.195 ± 0.037	6.247AlaIle: 6.247 ± 0.079	4.947AlaLys: 4.947 ± 0.07	7.058AlaLeu: 7.058 ± 0.082	2.005AlaMet: 2.005 ± 0.043	2.926AlaAsn: 2.926 ± 0.059	1.845AlaPro: 1.845 ± 0.041	2.032AlaGln: 2.032 ± 0.045	2.251AlaArg: 2.251 ± 0.045	3.971AlaSer: 3.971 ± 0.065	4.112AlaThr: 4.112 ± 0.07	4.407AlaVal: 4.407 ± 0.068	0.549AlaTrp: 0.549 ± 0.021	3.007AlaTyr: 3.007 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.647CysAla: 0.647 ± 0.025	0.211CysCys: 0.211 ± 0.014	0.668CysAsp: 0.668 ± 0.021	0.844CysGlu: 0.844 ± 0.026	0.561CysPhe: 0.561 ± 0.019	0.991CysGly: 0.991 ± 0.035	0.28CysHis: 0.28 ± 0.017	1.167CysIle: 1.167 ± 0.03	0.911CysLys: 0.911 ± 0.028	1.047CysLeu: 1.047 ± 0.029	0.371CysMet: 0.371 ± 0.016	0.612CysAsn: 0.612 ± 0.023	0.46CysPro: 0.46 ± 0.021	0.349CysGln: 0.349 ± 0.016	0.382CysArg: 0.382 ± 0.018	0.782CysSer: 0.782 ± 0.029	0.676CysThr: 0.676 ± 0.023	0.692CysVal: 0.692 ± 0.023	0.086CysTrp: 0.086 ± 0.008	0.568CysTyr: 0.568 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.03AspAla: 3.03 ± 0.056	0.579AspCys: 0.579 ± 0.023	2.161AspAsp: 2.161 ± 0.047	4.451AspGlu: 4.451 ± 0.057	2.383AspPhe: 2.383 ± 0.045	3.339AspGly: 3.339 ± 0.06	0.805AspHis: 0.805 ± 0.027	4.519AspIle: 4.519 ± 0.064	3.56AspLys: 3.56 ± 0.059	4.716AspLeu: 4.716 ± 0.065	1.41AspMet: 1.41 ± 0.03	2.243AspAsn: 2.243 ± 0.048	1.44AspPro: 1.44 ± 0.038	1.515AspGln: 1.515 ± 0.034	1.658AspArg: 1.658 ± 0.031	2.653AspSer: 2.653 ± 0.047	2.966AspThr: 2.966 ± 0.054	3.221AspVal: 3.221 ± 0.049	0.515AspTrp: 0.515 ± 0.019	2.73AspTyr: 2.73 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	6.275GluAla: 6.275 ± 0.088	0.69GluCys: 0.69 ± 0.022	3.991GluAsp: 3.991 ± 0.062	7.699GluGlu: 7.699 ± 0.102	2.305GluPhe: 2.305 ± 0.048	4.835GluGly: 4.835 ± 0.075	1.289GluHis: 1.289 ± 0.032	6.153GluIle: 6.153 ± 0.078	6.528GluLys: 6.528 ± 0.082	6.85GluLeu: 6.85 ± 0.087	2.389GluMet: 2.389 ± 0.044	3.852GluAsn: 3.852 ± 0.055	1.826GluPro: 1.826 ± 0.042	3.127GluGln: 3.127 ± 0.063	2.972GluArg: 2.972 ± 0.056	3.494GluSer: 3.494 ± 0.054	3.718GluThr: 3.718 ± 0.049	5.85GluVal: 5.85 ± 0.074	0.693GluTrp: 0.693 ± 0.025	2.8GluTyr: 2.8 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	2.496PheAla: 2.496 ± 0.046	0.596PheCys: 0.596 ± 0.021	2.176PheAsp: 2.176 ± 0.034	2.798PheGlu: 2.798 ± 0.051	1.74PhePhe: 1.74 ± 0.039	2.592PheGly: 2.592 ± 0.05	0.61PheHis: 0.61 ± 0.023	3.743PheIle: 3.743 ± 0.064	3.169PheLys: 3.169 ± 0.054	3.474PheLeu: 3.474 ± 0.052	1.112PheMet: 1.112 ± 0.031	2.302PheAsn: 2.302 ± 0.053	1.121PhePro: 1.121 ± 0.029	1.026PheGln: 1.026 ± 0.031	1.153PheArg: 1.153 ± 0.026	2.751PheSer: 2.751 ± 0.042	2.475PheThr: 2.475 ± 0.045	2.551PheVal: 2.551 ± 0.05	0.385PheTrp: 0.385 ± 0.017	1.785PheTyr: 1.785 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.48GlyAla: 4.48 ± 0.075	1.064GlyCys: 1.064 ± 0.032	3.288GlyAsp: 3.288 ± 0.054	4.887GlyGlu: 4.887 ± 0.069	2.892GlyPhe: 2.892 ± 0.049	4.319GlyGly: 4.319 ± 0.08	1.161GlyHis: 1.161 ± 0.033	6.441GlyIle: 6.441 ± 0.075	5.227GlyLys: 5.227 ± 0.059	6.009GlyLeu: 6.009 ± 0.073	2.126GlyMet: 2.126 ± 0.043	3.086GlyAsn: 3.086 ± 0.068	1.292GlyPro: 1.292 ± 0.038	2.002GlyGln: 2.002 ± 0.045	2.231GlyArg: 2.231 ± 0.041	3.855GlySer: 3.855 ± 0.056	3.935GlyThr: 3.935 ± 0.071	4.619GlyVal: 4.619 ± 0.065	0.57GlyTrp: 0.57 ± 0.024	3.173GlyTyr: 3.173 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	0.88HisAla: 0.88 ± 0.027	0.259HisCys: 0.259 ± 0.016	0.739HisAsp: 0.739 ± 0.027	1.069HisGlu: 1.069 ± 0.03	0.922HisPhe: 0.922 ± 0.026	0.984HisGly: 0.984 ± 0.03	0.465HisHis: 0.465 ± 0.021	1.666HisIle: 1.666 ± 0.04	1.104HisLys: 1.104 ± 0.035	1.806HisLeu: 1.806 ± 0.041	0.58HisMet: 0.58 ± 0.021	0.73HisAsn: 0.73 ± 0.023	0.751HisPro: 0.751 ± 0.026	0.661HisGln: 0.661 ± 0.026	0.583HisArg: 0.583 ± 0.021	1.014HisSer: 1.014 ± 0.028	1.073HisThr: 1.073 ± 0.034	0.983HisVal: 0.983 ± 0.027	0.169HisTrp: 0.169 ± 0.011	0.953HisTyr: 0.953 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.029IleAla: 6.029 ± 0.085	1.188IleCys: 1.188 ± 0.03	4.525IleAsp: 4.525 ± 0.058	6.666IleGlu: 6.666 ± 0.083	3.066IlePhe: 3.066 ± 0.052	6.122IleGly: 6.122 ± 0.071	1.393IleHis: 1.393 ± 0.037	6.902IleIle: 6.902 ± 0.101	6.431IleLys: 6.431 ± 0.076	7.659IleLeu: 7.659 ± 0.104	2.138IleMet: 2.138 ± 0.048	4.285IleAsn: 4.285 ± 0.062	3.202IlePro: 3.202 ± 0.047	2.653IleGln: 2.653 ± 0.05	2.928IleArg: 2.928 ± 0.049	5.507IleSer: 5.507 ± 0.075	4.968IleThr: 4.968 ± 0.063	5.428IleVal: 5.428 ± 0.075	0.66IleTrp: 0.66 ± 0.023	3.312IleTyr: 3.312 ± 0.055	0.0IleXaa: 0.0 ± 0.0
Lys	5.632LysAla: 5.632 ± 0.07	0.712LysCys: 0.712 ± 0.027	4.241LysAsp: 4.241 ± 0.059	7.975LysGlu: 7.975 ± 0.103	1.844LysPhe: 1.844 ± 0.044	4.959LysGly: 4.959 ± 0.071	1.274LysHis: 1.274 ± 0.035	5.107LysIle: 5.107 ± 0.068	6.057LysLys: 6.057 ± 0.078	6.544LysLeu: 6.544 ± 0.074	2.158LysMet: 2.158 ± 0.046	3.751LysAsn: 3.751 ± 0.05	2.088LysPro: 2.088 ± 0.041	3.404LysGln: 3.404 ± 0.053	3.03LysArg: 3.03 ± 0.05	3.758LysSer: 3.758 ± 0.054	3.835LysThr: 3.835 ± 0.054	5.686LysVal: 5.686 ± 0.066	0.758LysTrp: 0.758 ± 0.025	3.136LysTyr: 3.136 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	6.484LeuAla: 6.484 ± 0.078	1.258LeuCys: 1.258 ± 0.035	4.746LeuAsp: 4.746 ± 0.057	7.345LeuGlu: 7.345 ± 0.094	3.986LeuPhe: 3.986 ± 0.061	6.459LeuGly: 6.459 ± 0.077	1.397LeuHis: 1.397 ± 0.033	7.303LeuIle: 7.303 ± 0.085	7.394LeuLys: 7.394 ± 0.084	9.155LeuLeu: 9.155 ± 0.118	2.569LeuMet: 2.569 ± 0.047	4.392LeuAsn: 4.392 ± 0.06	3.307LeuPro: 3.307 ± 0.064	3.067LeuGln: 3.067 ± 0.056	3.271LeuArg: 3.271 ± 0.055	6.493LeuSer: 6.493 ± 0.085	5.299LeuThr: 5.299 ± 0.07	5.987LeuVal: 5.987 ± 0.076	0.754LeuTrp: 0.754 ± 0.025	3.543LeuTyr: 3.543 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.102MetAla: 2.102 ± 0.037	0.295MetCys: 0.295 ± 0.016	1.366MetAsp: 1.366 ± 0.03	1.786MetGlu: 1.786 ± 0.041	0.854MetPhe: 0.854 ± 0.028	1.904MetGly: 1.904 ± 0.04	0.45MetHis: 0.45 ± 0.021	2.352MetIle: 2.352 ± 0.04	2.5MetLys: 2.5 ± 0.042	2.62MetLeu: 2.62 ± 0.044	0.869MetMet: 0.869 ± 0.026	1.629MetAsn: 1.629 ± 0.035	1.163MetPro: 1.163 ± 0.036	1.112MetGln: 1.112 ± 0.033	1.088MetArg: 1.088 ± 0.028	1.913MetSer: 1.913 ± 0.038	1.643MetThr: 1.643 ± 0.037	1.665MetVal: 1.665 ± 0.036	0.216MetTrp: 0.216 ± 0.012	0.874MetTyr: 0.874 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	2.98AsnAla: 2.98 ± 0.05	0.556AsnCys: 0.556 ± 0.023	2.14AsnAsp: 2.14 ± 0.037	3.679AsnGlu: 3.679 ± 0.049	1.708AsnPhe: 1.708 ± 0.04	3.287AsnGly: 3.287 ± 0.06	0.981AsnHis: 0.981 ± 0.03	4.07AsnIle: 4.07 ± 0.057	3.953AsnLys: 3.953 ± 0.052	4.29AsnLeu: 4.29 ± 0.062	1.373AsnMet: 1.373 ± 0.029	2.562AsnAsn: 2.562 ± 0.056	1.928AsnPro: 1.928 ± 0.041	2.103AsnGln: 2.103 ± 0.041	1.701AsnArg: 1.701 ± 0.034	2.65AsnSer: 2.65 ± 0.052	2.943AsnThr: 2.943 ± 0.058	3.007AsnVal: 3.007 ± 0.056	0.512AsnTrp: 0.512 ± 0.024	2.149AsnTyr: 2.149 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	1.796ProAla: 1.796 ± 0.045	0.369ProCys: 0.369 ± 0.018	1.493ProAsp: 1.493 ± 0.038	2.523ProGlu: 2.523 ± 0.047	1.487ProPhe: 1.487 ± 0.032	1.742ProGly: 1.742 ± 0.043	0.611ProHis: 0.611 ± 0.021	2.998ProIle: 2.998 ± 0.052	2.045ProLys: 2.045 ± 0.045	2.858ProLeu: 2.858 ± 0.054	0.826ProMet: 0.826 ± 0.023	1.571ProAsn: 1.571 ± 0.04	0.713ProPro: 0.713 ± 0.028	1.026ProGln: 1.026 ± 0.029	0.892ProArg: 0.892 ± 0.024	2.059ProSer: 2.059 ± 0.046	2.072ProThr: 2.072 ± 0.063	2.25ProVal: 2.25 ± 0.053	0.299ProTrp: 0.299 ± 0.015	1.528ProTyr: 1.528 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.0GlnAla: 2.0 ± 0.044	0.344GlnCys: 0.344 ± 0.019	1.66GlnAsp: 1.66 ± 0.04	2.739GlnGlu: 2.739 ± 0.057	1.335GlnPhe: 1.335 ± 0.033	2.33GlnGly: 2.33 ± 0.051	0.489GlnHis: 0.489 ± 0.02	3.027GlnIle: 3.027 ± 0.048	2.662GlnLys: 2.662 ± 0.05	3.638GlnLeu: 3.638 ± 0.052	1.185GlnMet: 1.185 ± 0.033	1.633GlnAsn: 1.633 ± 0.034	0.798GlnPro: 0.798 ± 0.026	1.269GlnGln: 1.269 ± 0.045	1.233GlnArg: 1.233 ± 0.031	1.789GlnSer: 1.789 ± 0.042	1.87GlnThr: 1.87 ± 0.043	2.627GlnVal: 2.627 ± 0.051	0.266GlnTrp: 0.266 ± 0.015	1.485GlnTyr: 1.485 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.08ArgAla: 2.08 ± 0.039	0.423ArgCys: 0.423 ± 0.019	1.631ArgAsp: 1.631 ± 0.039	2.782ArgGlu: 2.782 ± 0.055	1.522ArgPhe: 1.522 ± 0.033	2.153ArgGly: 2.153 ± 0.038	0.646ArgHis: 0.646 ± 0.025	2.994ArgIle: 2.994 ± 0.046	2.67ArgLys: 2.67 ± 0.053	3.452ArgLeu: 3.452 ± 0.057	1.109ArgMet: 1.109 ± 0.029	1.675ArgAsn: 1.675 ± 0.037	0.983ArgPro: 0.983 ± 0.028	1.277ArgGln: 1.277 ± 0.037	1.517ArgArg: 1.517 ± 0.041	1.843ArgSer: 1.843 ± 0.039	1.867ArgThr: 1.867 ± 0.041	2.305ArgVal: 2.305 ± 0.043	0.341ArgTrp: 0.341 ± 0.018	1.663ArgTyr: 1.663 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.544SerAla: 3.544 ± 0.049	0.708SerCys: 0.708 ± 0.025	2.809SerAsp: 2.809 ± 0.055	3.883SerGlu: 3.883 ± 0.059	2.856SerPhe: 2.856 ± 0.047	4.205SerGly: 4.205 ± 0.072	1.139SerHis: 1.139 ± 0.031	5.371SerIle: 5.371 ± 0.072	4.359SerLys: 4.359 ± 0.063	5.673SerLeu: 5.673 ± 0.069	1.632SerMet: 1.632 ± 0.038	2.837SerAsn: 2.837 ± 0.05	1.883SerPro: 1.883 ± 0.043	2.023SerGln: 2.023 ± 0.044	2.07SerArg: 2.07 ± 0.041	4.043SerSer: 4.043 ± 0.079	3.583SerThr: 3.583 ± 0.053	3.577SerVal: 3.577 ± 0.053	0.557SerTrp: 0.557 ± 0.019	2.809SerTyr: 2.809 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.894ThrAla: 3.894 ± 0.066	0.563ThrCys: 0.563 ± 0.022	2.687ThrAsp: 2.687 ± 0.051	3.362ThrGlu: 3.362 ± 0.054	2.54ThrPhe: 2.54 ± 0.053	3.98ThrGly: 3.98 ± 0.073	1.111ThrHis: 1.111 ± 0.032	4.928ThrIle: 4.928 ± 0.058	3.924ThrLys: 3.924 ± 0.05	6.021ThrLeu: 6.021 ± 0.069	1.357ThrMet: 1.357 ± 0.03	2.704ThrAsn: 2.704 ± 0.055	2.401ThrPro: 2.401 ± 0.059	1.877ThrGln: 1.877 ± 0.044	1.808ThrArg: 1.808 ± 0.039	3.776ThrSer: 3.776 ± 0.072	3.718ThrThr: 3.718 ± 0.072	3.912ThrVal: 3.912 ± 0.065	0.512ThrTrp: 0.512 ± 0.02	2.809ThrTyr: 2.809 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	4.947ValAla: 4.947 ± 0.068	0.916ValCys: 0.916 ± 0.024	3.528ValAsp: 3.528 ± 0.055	4.599ValGlu: 4.599 ± 0.066	2.703ValPhe: 2.703 ± 0.05	4.574ValGly: 4.574 ± 0.061	0.993ValHis: 0.993 ± 0.027	5.692ValIle: 5.692 ± 0.067	4.719ValLys: 4.719 ± 0.07	6.29ValLeu: 6.29 ± 0.071	1.763ValMet: 1.763 ± 0.042	3.15ValAsn: 3.15 ± 0.05	2.32ValPro: 2.32 ± 0.049	2.002ValGln: 2.002 ± 0.038	2.244ValArg: 2.244 ± 0.046	4.152ValSer: 4.152 ± 0.062	4.082ValThr: 4.082 ± 0.059	4.859ValVal: 4.859 ± 0.075	0.536ValTrp: 0.536 ± 0.022	2.596ValTyr: 2.596 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.49TrpAla: 0.49 ± 0.021	0.15TrpCys: 0.15 ± 0.009	0.525TrpAsp: 0.525 ± 0.022	0.613TrpGlu: 0.613 ± 0.021	0.358TrpPhe: 0.358 ± 0.017	0.685TrpGly: 0.685 ± 0.023	0.19TrpHis: 0.19 ± 0.011	0.737TrpIle: 0.737 ± 0.022	0.552TrpLys: 0.552 ± 0.021	0.922TrpLeu: 0.922 ± 0.026	0.247TrpMet: 0.247 ± 0.014	0.457TrpAsn: 0.457 ± 0.019	0.196TrpPro: 0.196 ± 0.013	0.432TrpGln: 0.432 ± 0.019	0.319TrpArg: 0.319 ± 0.016	0.54TrpSer: 0.54 ± 0.02	0.413TrpThr: 0.413 ± 0.022	0.513TrpVal: 0.513 ± 0.018	0.13TrpTrp: 0.13 ± 0.011	0.417TrpTyr: 0.417 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.57TyrAla: 2.57 ± 0.042	0.566TyrCys: 0.566 ± 0.021	2.355TyrAsp: 2.355 ± 0.058	3.271TyrGlu: 3.271 ± 0.055	1.95TyrPhe: 1.95 ± 0.04	2.819TyrGly: 2.819 ± 0.048	0.913TyrHis: 0.913 ± 0.027	3.644TyrIle: 3.644 ± 0.054	3.237TyrLys: 3.237 ± 0.059	4.13TyrLeu: 4.13 ± 0.062	1.181TyrMet: 1.181 ± 0.03	2.176TyrAsn: 2.176 ± 0.043	1.439TyrPro: 1.439 ± 0.035	1.426TyrGln: 1.426 ± 0.035	1.603TyrArg: 1.603 ± 0.034	2.521TyrSer: 2.521 ± 0.052	2.635TyrThr: 2.635 ± 0.055	2.527TyrVal: 2.527 ± 0.046	0.377TyrTrp: 0.377 ± 0.017	2.055TyrTyr: 2.055 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4150 proteins (1326943 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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