Amino acid dipepetide frequency for Hubei unio douglasiae virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.234AlaAla: 4.234 ± 1.682
1.693AlaCys: 1.693 ± 0.612
2.54AlaAsp: 2.54 ± 1.54
2.54AlaGlu: 2.54 ± 1.021
2.54AlaPhe: 2.54 ± 1.021
5.927AlaGly: 5.927 ± 1.33
1.693AlaHis: 1.693 ± 0.612
0.847AlaIle: 0.847 ± 0.727
4.234AlaLys: 4.234 ± 0.889
3.387AlaLeu: 3.387 ± 1.905
3.387AlaMet: 3.387 ± 0.327
5.08AlaAsn: 5.08 ± 2.774
9.314AlaPro: 9.314 ± 2.638
1.693AlaGln: 1.693 ± 0.734
5.08AlaArg: 5.08 ± 0.958
11.854AlaSer: 11.854 ± 2.628
2.54AlaThr: 2.54 ± 1.214
2.54AlaVal: 2.54 ± 0.305
0.847AlaTrp: 0.847 ± 0.727
0.847AlaTyr: 0.847 ± 0.839
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.847CysCys: 0.847 ± 0.727
0.0CysAsp: 0.0 ± 0.0
3.387CysGlu: 3.387 ± 1.224
0.0CysPhe: 0.0 ± 0.0
0.847CysGly: 0.847 ± 0.578
0.0CysHis: 0.0 ± 0.0
0.847CysIle: 0.847 ± 0.727
0.847CysLys: 0.847 ± 0.578
0.847CysLeu: 0.847 ± 0.727
1.693CysMet: 1.693 ± 0.612
2.54CysAsn: 2.54 ± 0.305
0.0CysPro: 0.0 ± 0.0
0.847CysGln: 0.847 ± 0.727
1.693CysArg: 1.693 ± 0.864
0.0CysSer: 0.0 ± 0.0
1.693CysThr: 1.693 ± 1.156
2.54CysVal: 2.54 ± 1.021
0.0CysTrp: 0.0 ± 0.0
0.847CysTyr: 0.847 ± 0.727
0.0CysXaa: 0.0 ± 0.0
Asp
5.08AspAla: 5.08 ± 0.609
0.847AspCys: 0.847 ± 0.578
1.693AspAsp: 1.693 ± 1.455
0.847AspGlu: 0.847 ± 0.839
1.693AspPhe: 1.693 ± 1.455
1.693AspGly: 1.693 ± 0.864
2.54AspHis: 2.54 ± 0.942
3.387AspIle: 3.387 ± 1.104
5.08AspLys: 5.08 ± 0.609
4.234AspLeu: 4.234 ± 1.541
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
5.08AspPro: 5.08 ± 0.651
0.847AspGln: 0.847 ± 0.727
0.847AspArg: 0.847 ± 0.578
1.693AspSer: 1.693 ± 0.612
0.847AspThr: 0.847 ± 0.578
1.693AspVal: 1.693 ± 0.734
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.693GluAla: 1.693 ± 0.612
2.54GluCys: 2.54 ± 0.942
1.693GluAsp: 1.693 ± 0.612
5.927GluGlu: 5.927 ± 3.103
2.54GluPhe: 2.54 ± 1.467
3.387GluGly: 3.387 ± 1.439
2.54GluHis: 2.54 ± 1.214
0.847GluIle: 0.847 ± 0.578
2.54GluLys: 2.54 ± 0.942
1.693GluLeu: 1.693 ± 1.156
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
3.387GluPro: 3.387 ± 1.488
4.234GluGln: 4.234 ± 2.688
5.08GluArg: 5.08 ± 0.651
3.387GluSer: 3.387 ± 1.468
1.693GluThr: 1.693 ± 0.612
5.08GluVal: 5.08 ± 2.042
2.54GluTrp: 2.54 ± 1.54
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.693PheAla: 1.693 ± 0.612
0.847PheCys: 0.847 ± 0.727
3.387PheAsp: 3.387 ± 0.84
0.0PheGlu: 0.0 ± 0.0
0.847PhePhe: 0.847 ± 0.839
3.387PheGly: 3.387 ± 2.325
0.847PheHis: 0.847 ± 0.578
1.693PheIle: 1.693 ± 0.734
0.847PheLys: 0.847 ± 0.578
3.387PheLeu: 3.387 ± 2.002
2.54PheMet: 2.54 ± 1.54
0.847PheAsn: 0.847 ± 0.727
0.0PhePro: 0.0 ± 0.0
3.387PheGln: 3.387 ± 0.327
3.387PheArg: 3.387 ± 2.274
0.847PheSer: 0.847 ± 0.727
0.847PheThr: 0.847 ± 0.727
2.54PheVal: 2.54 ± 1.735
0.0PheTrp: 0.0 ± 0.0
1.693PheTyr: 1.693 ± 0.612
0.0PheXaa: 0.0 ± 0.0
Gly
4.234GlyAla: 4.234 ± 2.162
0.847GlyCys: 0.847 ± 0.839
2.54GlyAsp: 2.54 ± 1.214
1.693GlyGlu: 1.693 ± 1.156
5.08GlyPhe: 5.08 ± 1.664
6.774GlyGly: 6.774 ± 2.323
1.693GlyHis: 1.693 ± 0.612
5.08GlyIle: 5.08 ± 0.609
5.927GlyLys: 5.927 ± 3.111
2.54GlyLeu: 2.54 ± 0.305
1.693GlyMet: 1.693 ± 1.455
3.387GlyAsn: 3.387 ± 0.327
1.693GlyPro: 1.693 ± 0.612
4.234GlyGln: 4.234 ± 1.16
6.774GlyArg: 6.774 ± 3.686
7.621GlySer: 7.621 ± 1.24
5.927GlyThr: 5.927 ± 0.256
5.927GlyVal: 5.927 ± 2.492
2.54GlyTrp: 2.54 ± 0.305
1.693GlyTyr: 1.693 ± 0.864
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.847HisCys: 0.847 ± 0.727
0.847HisAsp: 0.847 ± 0.727
0.847HisGlu: 0.847 ± 0.727
0.847HisPhe: 0.847 ± 0.578
2.54HisGly: 2.54 ± 0.305
0.0HisHis: 0.0 ± 0.0
0.847HisIle: 0.847 ± 0.727
0.847HisLys: 0.847 ± 0.578
0.847HisLeu: 0.847 ± 0.578
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.387HisPro: 3.387 ± 1.224
0.0HisGln: 0.0 ± 0.0
0.847HisArg: 0.847 ± 0.578
2.54HisSer: 2.54 ± 0.942
0.847HisThr: 0.847 ± 0.839
1.693HisVal: 1.693 ± 1.455
1.693HisTrp: 1.693 ± 1.455
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.54IleAla: 2.54 ± 1.36
1.693IleCys: 1.693 ± 0.864
2.54IleAsp: 2.54 ± 2.182
2.54IleGlu: 2.54 ± 1.36
0.847IlePhe: 0.847 ± 0.727
5.08IleGly: 5.08 ± 3.335
0.0IleHis: 0.0 ± 0.0
1.693IleIle: 1.693 ± 0.612
1.693IleLys: 1.693 ± 0.734
2.54IleLeu: 2.54 ± 0.942
0.847IleMet: 0.847 ± 0.839
1.693IleAsn: 1.693 ± 0.612
2.54IlePro: 2.54 ± 1.021
5.08IleGln: 5.08 ± 0.651
4.234IleArg: 4.234 ± 0.48
3.387IleSer: 3.387 ± 1.104
2.54IleThr: 2.54 ± 1.36
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.693IleTyr: 1.693 ± 0.734
0.0IleXaa: 0.0 ± 0.0
Lys
4.234LysAla: 4.234 ± 0.889
0.847LysCys: 0.847 ± 0.727
0.847LysAsp: 0.847 ± 0.727
3.387LysGlu: 3.387 ± 2.313
1.693LysPhe: 1.693 ± 1.455
4.234LysGly: 4.234 ± 1.682
0.847LysHis: 0.847 ± 0.727
2.54LysIle: 2.54 ± 0.305
4.234LysLys: 4.234 ± 0.889
4.234LysLeu: 4.234 ± 1.779
3.387LysMet: 3.387 ± 2.003
3.387LysAsn: 3.387 ± 0.327
3.387LysPro: 3.387 ± 0.327
4.234LysGln: 4.234 ± 0.48
3.387LysArg: 3.387 ± 1.439
6.774LysSer: 6.774 ± 3.672
4.234LysThr: 4.234 ± 2.014
3.387LysVal: 3.387 ± 1.468
1.693LysTrp: 1.693 ± 0.734
2.54LysTyr: 2.54 ± 2.182
0.0LysXaa: 0.0 ± 0.0
Leu
3.387LeuAla: 3.387 ± 1.439
0.0LeuCys: 0.0 ± 0.0
5.08LeuAsp: 5.08 ± 1.188
5.927LeuGlu: 5.927 ± 1.911
0.847LeuPhe: 0.847 ± 0.839
4.234LeuGly: 4.234 ± 1.16
2.54LeuHis: 2.54 ± 1.214
2.54LeuIle: 2.54 ± 0.942
3.387LeuLys: 3.387 ± 1.905
5.08LeuLeu: 5.08 ± 1.188
0.0LeuMet: 0.0 ± 0.0
2.54LeuAsn: 2.54 ± 1.021
6.774LeuPro: 6.774 ± 1.675
2.54LeuGln: 2.54 ± 1.36
2.54LeuArg: 2.54 ± 1.467
5.927LeuSer: 5.927 ± 1.911
5.08LeuThr: 5.08 ± 1.842
4.234LeuVal: 4.234 ± 0.48
0.0LeuTrp: 0.0 ± 0.0
2.54LeuTyr: 2.54 ± 1.36
0.0LeuXaa: 0.0 ± 0.0
Met
2.54MetAla: 2.54 ± 1.36
0.847MetCys: 0.847 ± 0.578
0.847MetAsp: 0.847 ± 0.578
1.693MetGlu: 1.693 ± 1.678
2.54MetPhe: 2.54 ± 1.36
0.847MetGly: 0.847 ± 0.727
0.0MetHis: 0.0 ± 0.0
1.693MetIle: 1.693 ± 0.864
0.847MetLys: 0.847 ± 0.578
1.693MetLeu: 1.693 ± 1.455
0.847MetMet: 0.847 ± 0.727
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.847MetGln: 0.847 ± 0.839
2.54MetArg: 2.54 ± 0.942
5.08MetSer: 5.08 ± 1.188
4.234MetThr: 4.234 ± 1.937
1.693MetVal: 1.693 ± 1.455
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.927AsnAla: 5.927 ± 1.33
1.693AsnCys: 1.693 ± 0.734
0.847AsnAsp: 0.847 ± 0.578
2.54AsnGlu: 2.54 ± 1.021
0.0AsnPhe: 0.0 ± 0.0
4.234AsnGly: 4.234 ± 1.16
0.847AsnHis: 0.847 ± 0.727
0.0AsnIle: 0.0 ± 0.0
2.54AsnLys: 2.54 ± 0.942
5.927AsnLeu: 5.927 ± 1.385
1.693AsnMet: 1.693 ± 0.864
0.847AsnAsn: 0.847 ± 0.578
1.693AsnPro: 1.693 ± 0.612
1.693AsnGln: 1.693 ± 0.734
5.08AsnArg: 5.08 ± 2.538
1.693AsnSer: 1.693 ± 0.864
2.54AsnThr: 2.54 ± 0.305
4.234AsnVal: 4.234 ± 1.682
0.0AsnTrp: 0.0 ± 0.0
2.54AsnTyr: 2.54 ± 1.214
0.0AsnXaa: 0.0 ± 0.0
Pro
5.927ProAla: 5.927 ± 2.877
0.0ProCys: 0.0 ± 0.0
1.693ProAsp: 1.693 ± 1.156
0.0ProGlu: 0.0 ± 0.0
2.54ProPhe: 2.54 ± 1.214
2.54ProGly: 2.54 ± 1.021
0.847ProHis: 0.847 ± 0.839
6.774ProIle: 6.774 ± 1.221
5.927ProLys: 5.927 ± 1.33
2.54ProLeu: 2.54 ± 1.467
1.693ProMet: 1.693 ± 0.61
1.693ProAsn: 1.693 ± 1.156
5.927ProPro: 5.927 ± 2.04
1.693ProGln: 1.693 ± 1.156
5.08ProArg: 5.08 ± 0.651
8.467ProSer: 8.467 ± 1.229
7.621ProThr: 7.621 ± 3.103
4.234ProVal: 4.234 ± 3.637
1.693ProTrp: 1.693 ± 0.734
1.693ProTyr: 1.693 ± 0.612
0.0ProXaa: 0.0 ± 0.0
Gln
5.927GlnAla: 5.927 ± 1.566
1.693GlnCys: 1.693 ± 1.455
1.693GlnAsp: 1.693 ± 1.678
1.693GlnGlu: 1.693 ± 1.156
1.693GlnPhe: 1.693 ± 0.612
1.693GlnGly: 1.693 ± 1.156
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
3.387GlnLeu: 3.387 ± 0.327
2.54GlnMet: 2.54 ± 0.305
2.54GlnAsn: 2.54 ± 1.214
1.693GlnPro: 1.693 ± 1.156
3.387GlnGln: 3.387 ± 0.327
3.387GlnArg: 3.387 ± 2.002
2.54GlnSer: 2.54 ± 1.467
3.387GlnThr: 3.387 ± 1.729
0.847GlnVal: 0.847 ± 0.839
2.54GlnTrp: 2.54 ± 0.305
2.54GlnTyr: 2.54 ± 2.182
0.0GlnXaa: 0.0 ± 0.0
Arg
6.774ArgAla: 6.774 ± 0.655
1.693ArgCys: 1.693 ± 0.612
5.927ArgAsp: 5.927 ± 1.33
4.234ArgGlu: 4.234 ± 2.891
1.693ArgPhe: 1.693 ± 0.734
4.234ArgGly: 4.234 ± 0.48
1.693ArgHis: 1.693 ± 1.455
4.234ArgIle: 4.234 ± 1.16
6.774ArgLys: 6.774 ± 2.976
2.54ArgLeu: 2.54 ± 0.942
2.54ArgMet: 2.54 ± 1.36
5.08ArgAsn: 5.08 ± 1.464
3.387ArgPro: 3.387 ± 1.905
2.54ArgGln: 2.54 ± 1.467
4.234ArgArg: 4.234 ± 2.014
8.467ArgSer: 8.467 ± 2.888
0.847ArgThr: 0.847 ± 0.578
4.234ArgVal: 4.234 ± 0.48
0.0ArgTrp: 0.0 ± 0.0
0.847ArgTyr: 0.847 ± 0.727
0.0ArgXaa: 0.0 ± 0.0
Ser
6.774SerAla: 6.774 ± 2.684
1.693SerCys: 1.693 ± 1.156
4.234SerAsp: 4.234 ± 1.682
5.08SerGlu: 5.08 ± 1.664
0.847SerPhe: 0.847 ± 0.578
10.161SerGly: 10.161 ± 1.106
0.0SerHis: 0.0 ± 0.0
4.234SerIle: 4.234 ± 2.616
1.693SerLys: 1.693 ± 0.612
5.927SerLeu: 5.927 ± 2.995
0.847SerMet: 0.847 ± 0.839
6.774SerAsn: 6.774 ± 1.679
5.927SerPro: 5.927 ± 0.256
1.693SerGln: 1.693 ± 0.734
10.161SerArg: 10.161 ± 2.14
7.621SerSer: 7.621 ± 2.24
5.08SerThr: 5.08 ± 0.958
4.234SerVal: 4.234 ± 0.889
0.0SerTrp: 0.0 ± 0.0
5.927SerTyr: 5.927 ± 2.363
0.0SerXaa: 0.0 ± 0.0
Thr
5.927ThrAla: 5.927 ± 2.386
0.0ThrCys: 0.0 ± 0.0
0.847ThrAsp: 0.847 ± 0.727
4.234ThrGlu: 4.234 ± 1.48
1.693ThrPhe: 1.693 ± 0.734
5.927ThrGly: 5.927 ± 0.256
0.847ThrHis: 0.847 ± 0.578
0.847ThrIle: 0.847 ± 0.839
7.621ThrLys: 7.621 ± 1.24
2.54ThrLeu: 2.54 ± 0.305
1.693ThrMet: 1.693 ± 1.455
2.54ThrAsn: 2.54 ± 1.467
6.774ThrPro: 6.774 ± 1.675
1.693ThrGln: 1.693 ± 0.864
1.693ThrArg: 1.693 ± 1.455
6.774ThrSer: 6.774 ± 1.675
5.927ThrThr: 5.927 ± 2.492
5.927ThrVal: 5.927 ± 0.256
0.0ThrTrp: 0.0 ± 0.0
0.847ThrTyr: 0.847 ± 0.839
0.0ThrXaa: 0.0 ± 0.0
Val
2.54ValAla: 2.54 ± 1.36
0.847ValCys: 0.847 ± 0.578
0.847ValAsp: 0.847 ± 0.839
3.387ValGlu: 3.387 ± 0.84
1.693ValPhe: 1.693 ± 0.612
5.927ValGly: 5.927 ± 1.385
0.0ValHis: 0.0 ± 0.0
1.693ValIle: 1.693 ± 1.455
5.927ValLys: 5.927 ± 3.121
5.927ValLeu: 5.927 ± 1.566
2.54ValMet: 2.54 ± 1.021
5.08ValAsn: 5.08 ± 1.591
5.927ValPro: 5.927 ± 1.566
0.847ValGln: 0.847 ± 0.578
4.234ValArg: 4.234 ± 0.889
1.693ValSer: 1.693 ± 1.156
5.08ValThr: 5.08 ± 0.609
5.08ValVal: 5.08 ± 0.609
0.847ValTrp: 0.847 ± 0.839
1.693ValTyr: 1.693 ± 1.455
0.0ValXaa: 0.0 ± 0.0
Trp
0.847TrpAla: 0.847 ± 0.727
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.693TrpPhe: 1.693 ± 0.864
0.847TrpGly: 0.847 ± 0.727
0.847TrpHis: 0.847 ± 0.839
0.847TrpIle: 0.847 ± 0.839
0.847TrpLys: 0.847 ± 0.727
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.693TrpAsn: 1.693 ± 1.156
0.0TrpPro: 0.0 ± 0.0
0.847TrpGln: 0.847 ± 0.727
0.0TrpArg: 0.0 ± 0.0
2.54TrpSer: 2.54 ± 1.467
1.693TrpThr: 1.693 ± 0.612
0.847TrpVal: 0.847 ± 0.839
0.0TrpTrp: 0.0 ± 0.0
0.847TrpTyr: 0.847 ± 0.839
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.54TyrAla: 2.54 ± 1.214
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.847TyrGlu: 0.847 ± 0.727
1.693TyrPhe: 1.693 ± 0.864
3.387TyrGly: 3.387 ± 1.224
1.693TyrHis: 1.693 ± 0.612
2.54TyrIle: 2.54 ± 2.182
1.693TyrLys: 1.693 ± 1.455
5.927TyrLeu: 5.927 ± 0.256
0.0TyrMet: 0.0 ± 0.547
0.847TyrAsn: 0.847 ± 0.839
1.693TyrPro: 1.693 ± 1.678
0.847TyrGln: 0.847 ± 0.578
1.693TyrArg: 1.693 ± 1.455
0.0TyrSer: 0.0 ± 0.0
1.693TyrThr: 1.693 ± 0.612
0.847TyrVal: 0.847 ± 0.727
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1182 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski