Amino acid dipepetide frequency for Tessaracoccus oleiagri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.719AlaAla: 16.719 ± 0.21	0.809AlaCys: 0.809 ± 0.029	7.648AlaAsp: 7.648 ± 0.104	8.178AlaGlu: 8.178 ± 0.11	3.512AlaPhe: 3.512 ± 0.075	10.868AlaGly: 10.868 ± 0.125	2.475AlaHis: 2.475 ± 0.051	5.241AlaIle: 5.241 ± 0.091	3.07AlaLys: 3.07 ± 0.061	13.053AlaLeu: 13.053 ± 0.143	2.991AlaMet: 2.991 ± 0.058	2.354AlaAsn: 2.354 ± 0.047	5.677AlaPro: 5.677 ± 0.084	3.767AlaGln: 3.767 ± 0.068	8.676AlaArg: 8.676 ± 0.115	6.209AlaSer: 6.209 ± 0.09	6.904AlaThr: 6.904 ± 0.097	10.319AlaVal: 10.319 ± 0.106	1.908AlaTrp: 1.908 ± 0.053	2.253AlaTyr: 2.253 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.695CysAla: 0.695 ± 0.03	0.068CysCys: 0.068 ± 0.011	0.414CysAsp: 0.414 ± 0.023	0.35CysGlu: 0.35 ± 0.02	0.183CysPhe: 0.183 ± 0.013	0.724CysGly: 0.724 ± 0.03	0.162CysHis: 0.162 ± 0.015	0.207CysIle: 0.207 ± 0.015	0.086CysLys: 0.086 ± 0.009	0.537CysLeu: 0.537 ± 0.024	0.108CysMet: 0.108 ± 0.012	0.151CysAsn: 0.151 ± 0.014	0.41CysPro: 0.41 ± 0.021	0.15CysGln: 0.15 ± 0.011	0.407CysArg: 0.407 ± 0.026	0.376CysSer: 0.376 ± 0.018	0.4CysThr: 0.4 ± 0.02	0.491CysVal: 0.491 ± 0.024	0.076CysTrp: 0.076 ± 0.01	0.135CysTyr: 0.135 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.451AspAla: 7.451 ± 0.11	0.353AspCys: 0.353 ± 0.021	4.221AspAsp: 4.221 ± 0.082	5.318AspGlu: 5.318 ± 0.077	1.929AspPhe: 1.929 ± 0.053	6.135AspGly: 6.135 ± 0.103	1.41AspHis: 1.41 ± 0.041	2.263AspIle: 2.263 ± 0.051	1.098AspLys: 1.098 ± 0.037	6.388AspLeu: 6.388 ± 0.085	1.012AspMet: 1.012 ± 0.033	1.107AspAsn: 1.107 ± 0.038	4.152AspPro: 4.152 ± 0.064	1.741AspGln: 1.741 ± 0.049	4.208AspArg: 4.208 ± 0.071	2.462AspSer: 2.462 ± 0.046	2.745AspThr: 2.745 ± 0.053	5.833AspVal: 5.833 ± 0.076	0.991AspTrp: 0.991 ± 0.034	1.339AspTyr: 1.339 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.994GluAla: 7.994 ± 0.124	0.349GluCys: 0.349 ± 0.02	3.144GluAsp: 3.144 ± 0.064	4.028GluGlu: 4.028 ± 0.075	1.999GluPhe: 1.999 ± 0.047	4.961GluGly: 4.961 ± 0.073	1.64GluHis: 1.64 ± 0.038	2.707GluIle: 2.707 ± 0.058	1.446GluLys: 1.446 ± 0.044	7.31GluLeu: 7.31 ± 0.105	1.214GluMet: 1.214 ± 0.04	1.093GluAsn: 1.093 ± 0.034	3.375GluPro: 3.375 ± 0.066	2.378GluGln: 2.378 ± 0.057	5.397GluArg: 5.397 ± 0.081	3.089GluSer: 3.089 ± 0.06	3.056GluThr: 3.056 ± 0.053	5.443GluVal: 5.443 ± 0.081	0.892GluTrp: 0.892 ± 0.029	1.287GluTyr: 1.287 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.826PheAla: 3.826 ± 0.06	0.243PheCys: 0.243 ± 0.018	2.401PheAsp: 2.401 ± 0.049	1.906PheGlu: 1.906 ± 0.045	1.052PhePhe: 1.052 ± 0.033	3.358PheGly: 3.358 ± 0.062	0.683PheHis: 0.683 ± 0.026	1.197PheIle: 1.197 ± 0.037	0.607PheLys: 0.607 ± 0.028	3.052PheLeu: 3.052 ± 0.059	0.592PheMet: 0.592 ± 0.022	0.77PheAsn: 0.77 ± 0.029	1.467PhePro: 1.467 ± 0.038	0.832PheGln: 0.832 ± 0.03	1.992PheArg: 1.992 ± 0.052	1.763PheSer: 1.763 ± 0.05	2.04PheThr: 2.04 ± 0.045	2.882PheVal: 2.882 ± 0.062	0.501PheTrp: 0.501 ± 0.028	0.669PheTyr: 0.669 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.648GlyAla: 9.648 ± 0.106	0.643GlyCys: 0.643 ± 0.033	5.196GlyAsp: 5.196 ± 0.086	5.279GlyGlu: 5.279 ± 0.074	3.196GlyPhe: 3.196 ± 0.058	7.415GlyGly: 7.415 ± 0.133	2.076GlyHis: 2.076 ± 0.051	4.37GlyIle: 4.37 ± 0.073	2.399GlyLys: 2.399 ± 0.054	9.162GlyLeu: 9.162 ± 0.121	2.247GlyMet: 2.247 ± 0.045	1.892GlyAsn: 1.892 ± 0.055	3.852GlyPro: 3.852 ± 0.063	2.729GlyGln: 2.729 ± 0.057	6.632GlyArg: 6.632 ± 0.09	5.023GlySer: 5.023 ± 0.085	5.383GlyThr: 5.383 ± 0.077	7.616GlyVal: 7.616 ± 0.101	1.797GlyTrp: 1.797 ± 0.045	2.364GlyTyr: 2.364 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.37HisAla: 2.37 ± 0.051	0.156HisCys: 0.156 ± 0.012	1.462HisAsp: 1.462 ± 0.04	1.258HisGlu: 1.258 ± 0.036	0.648HisPhe: 0.648 ± 0.024	2.086HisGly: 2.086 ± 0.051	0.645HisHis: 0.645 ± 0.027	0.793HisIle: 0.793 ± 0.028	0.38HisLys: 0.38 ± 0.019	2.253HisLeu: 2.253 ± 0.052	0.378HisMet: 0.378 ± 0.02	0.449HisAsn: 0.449 ± 0.021	1.538HisPro: 1.538 ± 0.04	0.624HisGln: 0.624 ± 0.027	1.763HisArg: 1.763 ± 0.045	0.986HisSer: 0.986 ± 0.036	1.092HisThr: 1.092 ± 0.036	1.929HisVal: 1.929 ± 0.041	0.342HisTrp: 0.342 ± 0.018	0.488HisTyr: 0.488 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.736IleAla: 5.736 ± 0.089	0.296IleCys: 0.296 ± 0.019	3.192IleAsp: 3.192 ± 0.057	2.766IleGlu: 2.766 ± 0.062	1.175IlePhe: 1.175 ± 0.041	3.95IleGly: 3.95 ± 0.079	0.776IleHis: 0.776 ± 0.026	1.854IleIle: 1.854 ± 0.055	0.9IleLys: 0.9 ± 0.035	3.525IleLeu: 3.525 ± 0.071	0.694IleMet: 0.694 ± 0.027	1.049IleAsn: 1.049 ± 0.034	2.189IlePro: 2.189 ± 0.052	1.004IleGln: 1.004 ± 0.035	2.681IleArg: 2.681 ± 0.059	2.269IleSer: 2.269 ± 0.053	2.611IleThr: 2.611 ± 0.061	4.125IleVal: 4.125 ± 0.07	0.532IleTrp: 0.532 ± 0.024	0.789IleTyr: 0.789 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.576LysAla: 2.576 ± 0.055	0.104LysCys: 0.104 ± 0.011	1.207LysAsp: 1.207 ± 0.039	1.319LysGlu: 1.319 ± 0.04	0.665LysPhe: 0.665 ± 0.028	1.74LysGly: 1.74 ± 0.043	0.525LysHis: 0.525 ± 0.023	0.957LysIle: 0.957 ± 0.034	0.742LysLys: 0.742 ± 0.032	2.326LysLeu: 2.326 ± 0.049	0.471LysMet: 0.471 ± 0.023	0.505LysAsn: 0.505 ± 0.023	1.339LysPro: 1.339 ± 0.045	0.788LysGln: 0.788 ± 0.032	1.717LysArg: 1.717 ± 0.04	1.266LysSer: 1.266 ± 0.034	1.2LysThr: 1.2 ± 0.04	2.069LysVal: 2.069 ± 0.053	0.32LysTrp: 0.32 ± 0.017	0.561LysTyr: 0.561 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	14.03LeuAla: 14.03 ± 0.157	0.557LeuCys: 0.557 ± 0.023	6.69LeuAsp: 6.69 ± 0.082	5.82LeuGlu: 5.82 ± 0.083	3.055LeuPhe: 3.055 ± 0.065	9.798LeuGly: 9.798 ± 0.118	2.001LeuHis: 2.001 ± 0.048	3.862LeuIle: 3.862 ± 0.077	2.003LeuLys: 2.003 ± 0.047	10.426LeuLeu: 10.426 ± 0.158	1.955LeuMet: 1.955 ± 0.049	2.024LeuAsn: 2.024 ± 0.041	5.663LeuPro: 5.663 ± 0.08	2.708LeuGln: 2.708 ± 0.055	7.882LeuArg: 7.882 ± 0.103	5.509LeuSer: 5.509 ± 0.086	6.188LeuThr: 6.188 ± 0.083	9.755LeuVal: 9.755 ± 0.125	1.327LeuTrp: 1.327 ± 0.042	1.656LeuTyr: 1.656 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.643MetAla: 2.643 ± 0.052	0.118MetCys: 0.118 ± 0.012	1.025MetAsp: 1.025 ± 0.037	0.964MetGlu: 0.964 ± 0.032	0.647MetPhe: 0.647 ± 0.027	1.623MetGly: 1.623 ± 0.044	0.401MetHis: 0.401 ± 0.022	0.937MetIle: 0.937 ± 0.034	0.543MetLys: 0.543 ± 0.023	2.114MetLeu: 2.114 ± 0.05	0.451MetMet: 0.451 ± 0.026	0.592MetAsn: 0.592 ± 0.026	1.165MetPro: 1.165 ± 0.035	0.589MetGln: 0.589 ± 0.027	1.581MetArg: 1.581 ± 0.04	1.447MetSer: 1.447 ± 0.041	1.712MetThr: 1.712 ± 0.038	1.762MetVal: 1.762 ± 0.044	0.291MetTrp: 0.291 ± 0.016	0.335MetTyr: 0.335 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.385AsnAla: 2.385 ± 0.046	0.135AsnCys: 0.135 ± 0.012	1.163AsnAsp: 1.163 ± 0.038	1.153AsnGlu: 1.153 ± 0.041	0.727AsnPhe: 0.727 ± 0.028	1.786AsnGly: 1.786 ± 0.051	0.467AsnHis: 0.467 ± 0.02	0.906AsnIle: 0.906 ± 0.029	0.487AsnLys: 0.487 ± 0.025	2.108AsnLeu: 2.108 ± 0.044	0.41AsnMet: 0.41 ± 0.023	0.546AsnAsn: 0.546 ± 0.027	1.621AsnPro: 1.621 ± 0.042	0.646AsnGln: 0.646 ± 0.027	1.396AsnArg: 1.396 ± 0.039	1.035AsnSer: 1.035 ± 0.03	1.153AsnThr: 1.153 ± 0.037	1.761AsnVal: 1.761 ± 0.045	0.376AsnTrp: 0.376 ± 0.02	0.572AsnTyr: 0.572 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	6.262ProAla: 6.262 ± 0.097	0.248ProCys: 0.248 ± 0.017	3.993ProAsp: 3.993 ± 0.078	4.262ProGlu: 4.262 ± 0.061	1.622ProPhe: 1.622 ± 0.039	5.209ProGly: 5.209 ± 0.075	1.132ProHis: 1.132 ± 0.037	1.974ProIle: 1.974 ± 0.047	1.266ProLys: 1.266 ± 0.04	4.784ProLeu: 4.784 ± 0.076	1.082ProMet: 1.082 ± 0.027	1.129ProAsn: 1.129 ± 0.036	2.55ProPro: 2.55 ± 0.059	1.535ProGln: 1.535 ± 0.045	3.3ProArg: 3.3 ± 0.062	3.316ProSer: 3.316 ± 0.072	3.508ProThr: 3.508 ± 0.079	4.859ProVal: 4.859 ± 0.067	0.919ProTrp: 0.919 ± 0.032	1.119ProTyr: 1.119 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.515GlnAla: 3.515 ± 0.073	0.136GlnCys: 0.136 ± 0.011	1.229GlnAsp: 1.229 ± 0.034	1.643GlnGlu: 1.643 ± 0.045	0.959GlnPhe: 0.959 ± 0.029	2.224GlnGly: 2.224 ± 0.048	0.692GlnHis: 0.692 ± 0.03	1.317GlnIle: 1.317 ± 0.04	0.615GlnLys: 0.615 ± 0.028	3.598GlnLeu: 3.598 ± 0.077	0.579GlnMet: 0.579 ± 0.027	0.552GlnAsn: 0.552 ± 0.023	1.699GlnPro: 1.699 ± 0.048	1.343GlnGln: 1.343 ± 0.046	2.599GlnArg: 2.599 ± 0.063	1.472GlnSer: 1.472 ± 0.041	1.409GlnThr: 1.409 ± 0.038	2.663GlnVal: 2.663 ± 0.054	0.496GlnTrp: 0.496 ± 0.024	0.721GlnTyr: 0.721 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	8.405ArgAla: 8.405 ± 0.105	0.418ArgCys: 0.418 ± 0.023	4.433ArgAsp: 4.433 ± 0.073	4.683ArgGlu: 4.683 ± 0.073	2.61ArgPhe: 2.61 ± 0.055	5.306ArgGly: 5.306 ± 0.076	1.73ArgHis: 1.73 ± 0.044	3.47ArgIle: 3.47 ± 0.065	1.644ArgLys: 1.644 ± 0.041	7.801ArgLeu: 7.801 ± 0.122	1.73ArgMet: 1.73 ± 0.038	1.522ArgAsn: 1.522 ± 0.042	3.984ArgPro: 3.984 ± 0.067	2.248ArgGln: 2.248 ± 0.05	6.982ArgArg: 6.982 ± 0.103	3.817ArgSer: 3.817 ± 0.065	4.011ArgThr: 4.011 ± 0.071	5.902ArgVal: 5.902 ± 0.073	1.317ArgTrp: 1.317 ± 0.037	1.771ArgTyr: 1.771 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.043SerAla: 6.043 ± 0.085	0.307SerCys: 0.307 ± 0.02	3.019SerAsp: 3.019 ± 0.056	2.967SerGlu: 2.967 ± 0.058	1.787SerPhe: 1.787 ± 0.045	5.306SerGly: 5.306 ± 0.075	1.077SerHis: 1.077 ± 0.035	2.338SerIle: 2.338 ± 0.063	1.218SerLys: 1.218 ± 0.032	5.328SerLeu: 5.328 ± 0.077	1.331SerMet: 1.331 ± 0.042	1.104SerAsn: 1.104 ± 0.029	3.169SerPro: 3.169 ± 0.063	1.486SerGln: 1.486 ± 0.044	3.757SerArg: 3.757 ± 0.067	2.999SerSer: 2.999 ± 0.059	3.112SerThr: 3.112 ± 0.06	4.406SerVal: 4.406 ± 0.071	0.868SerTrp: 0.868 ± 0.031	1.266SerTyr: 1.266 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.585ThrAla: 6.585 ± 0.092	0.352ThrCys: 0.352 ± 0.024	3.417ThrAsp: 3.417 ± 0.058	3.067ThrGlu: 3.067 ± 0.059	1.952ThrPhe: 1.952 ± 0.045	5.507ThrGly: 5.507 ± 0.077	1.145ThrHis: 1.145 ± 0.03	2.738ThrIle: 2.738 ± 0.056	1.328ThrLys: 1.328 ± 0.041	5.736ThrLeu: 5.736 ± 0.084	1.268ThrMet: 1.268 ± 0.035	1.29ThrAsn: 1.29 ± 0.039	3.588ThrPro: 3.588 ± 0.068	1.499ThrGln: 1.499 ± 0.036	3.689ThrArg: 3.689 ± 0.056	3.136ThrSer: 3.136 ± 0.064	3.63ThrThr: 3.63 ± 0.076	5.557ThrVal: 5.557 ± 0.082	0.984ThrTrp: 0.984 ± 0.031	1.363ThrTyr: 1.363 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	11.753ValAla: 11.753 ± 0.127	0.562ValCys: 0.562 ± 0.027	6.106ValAsp: 6.106 ± 0.084	5.689ValGlu: 5.689 ± 0.078	2.723ValPhe: 2.723 ± 0.054	7.72ValGly: 7.72 ± 0.096	1.795ValHis: 1.795 ± 0.041	3.67ValIle: 3.67 ± 0.065	1.777ValLys: 1.777 ± 0.037	9.15ValLeu: 9.15 ± 0.134	1.778ValMet: 1.778 ± 0.048	1.806ValAsn: 1.806 ± 0.05	4.729ValPro: 4.729 ± 0.069	2.147ValGln: 2.147 ± 0.047	6.063ValArg: 6.063 ± 0.087	4.603ValSer: 4.603 ± 0.071	5.573ValThr: 5.573 ± 0.102	9.231ValVal: 9.231 ± 0.119	1.224ValTrp: 1.224 ± 0.043	1.553ValTyr: 1.553 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.634TrpAla: 1.634 ± 0.043	0.119TrpCys: 0.119 ± 0.01	0.85TrpAsp: 0.85 ± 0.029	0.808TrpGlu: 0.808 ± 0.029	0.585TrpPhe: 0.585 ± 0.025	1.21TrpGly: 1.21 ± 0.037	0.366TrpHis: 0.366 ± 0.02	0.634TrpIle: 0.634 ± 0.026	0.354TrpLys: 0.354 ± 0.019	2.022TrpLeu: 2.022 ± 0.053	0.338TrpMet: 0.338 ± 0.021	0.398TrpAsn: 0.398 ± 0.024	0.779TrpPro: 0.779 ± 0.028	0.629TrpGln: 0.629 ± 0.027	1.362TrpArg: 1.362 ± 0.04	0.925TrpSer: 0.925 ± 0.033	0.892TrpThr: 0.892 ± 0.036	1.258TrpVal: 1.258 ± 0.04	0.402TrpTrp: 0.402 ± 0.022	0.353TrpTyr: 0.353 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.358TyrAla: 2.358 ± 0.049	0.159TyrCys: 0.159 ± 0.012	1.348TyrAsp: 1.348 ± 0.044	1.342TyrGlu: 1.342 ± 0.033	0.803TyrPhe: 0.803 ± 0.035	1.992TyrGly: 1.992 ± 0.05	0.442TyrHis: 0.442 ± 0.021	0.679TyrIle: 0.679 ± 0.025	0.434TyrLys: 0.434 ± 0.02	2.235TyrLeu: 2.235 ± 0.057	0.309TyrMet: 0.309 ± 0.021	0.503TyrAsn: 0.503 ± 0.023	1.12TyrPro: 1.12 ± 0.033	0.618TyrGln: 0.618 ± 0.026	1.7TyrArg: 1.7 ± 0.046	1.187TyrSer: 1.187 ± 0.035	1.213TyrThr: 1.213 ± 0.038	1.794TyrVal: 1.794 ± 0.042	0.355TyrTrp: 0.355 ± 0.019	0.507TyrTyr: 0.507 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2895 proteins (980936 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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