Amino acid dipepetide frequency for Heterobasidion partitivirus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.22AlaAla: 5.22 ± 2.842
0.746AlaCys: 0.746 ± 0.558
4.474AlaAsp: 4.474 ± 1.22
0.746AlaGlu: 0.746 ± 0.506
1.491AlaPhe: 1.491 ± 0.052
5.966AlaGly: 5.966 ± 3.399
4.474AlaHis: 4.474 ± 0.157
3.729AlaIle: 3.729 ± 1.726
1.491AlaLys: 1.491 ± 1.116
5.22AlaLeu: 5.22 ± 0.349
1.491AlaMet: 1.491 ± 0.399
2.237AlaAsn: 2.237 ± 0.61
5.22AlaPro: 5.22 ± 2.842
2.983AlaGln: 2.983 ± 0.959
6.711AlaArg: 6.711 ± 0.767
5.22AlaSer: 5.22 ± 2.842
7.457AlaThr: 7.457 ± 2.388
2.237AlaVal: 2.237 ± 0.453
1.491AlaTrp: 1.491 ± 1.011
2.237AlaTyr: 2.237 ± 0.453
0.0AlaXaa: 0.0 ± 0.0
Cys
0.746CysAla: 0.746 ± 0.506
0.746CysCys: 0.746 ± 0.506
0.746CysAsp: 0.746 ± 0.558
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.746CysHis: 0.746 ± 0.558
0.746CysIle: 0.746 ± 0.506
0.0CysLys: 0.0 ± 0.0
0.746CysLeu: 0.746 ± 0.558
0.746CysMet: 0.746 ± 0.558
0.746CysAsn: 0.746 ± 0.506
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.746CysArg: 0.746 ± 0.506
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.237AspAla: 2.237 ± 0.453
0.746AspCys: 0.746 ± 0.558
6.711AspAsp: 6.711 ± 0.767
3.729AspGlu: 3.729 ± 0.401
4.474AspPhe: 4.474 ± 0.906
2.983AspGly: 2.983 ± 1.168
1.491AspHis: 1.491 ± 1.116
2.237AspIle: 2.237 ± 0.61
3.729AspLys: 3.729 ± 1.464
5.22AspLeu: 5.22 ± 1.412
0.0AspMet: 0.0 ± 0.0
3.729AspAsn: 3.729 ± 0.401
5.22AspPro: 5.22 ± 0.715
2.983AspGln: 2.983 ± 0.959
2.237AspArg: 2.237 ± 0.453
2.983AspSer: 2.983 ± 0.959
5.22AspThr: 5.22 ± 0.715
5.966AspVal: 5.966 ± 1.273
0.746AspTrp: 0.746 ± 0.506
0.746AspTyr: 0.746 ± 0.558
0.0AspXaa: 0.0 ± 0.0
Glu
1.491GluAla: 1.491 ± 0.052
0.746GluCys: 0.746 ± 0.506
1.491GluAsp: 1.491 ± 1.011
2.983GluGlu: 2.983 ± 0.959
2.983GluPhe: 2.983 ± 2.022
0.746GluGly: 0.746 ± 0.558
2.983GluHis: 2.983 ± 1.168
1.491GluIle: 1.491 ± 0.052
0.746GluLys: 0.746 ± 0.506
2.983GluLeu: 2.983 ± 1.168
0.746GluMet: 0.746 ± 0.506
2.237GluAsn: 2.237 ± 0.453
1.491GluPro: 1.491 ± 1.116
2.237GluGln: 2.237 ± 0.453
1.491GluArg: 1.491 ± 0.052
4.474GluSer: 4.474 ± 1.97
2.983GluThr: 2.983 ± 0.105
2.237GluVal: 2.237 ± 0.453
0.0GluTrp: 0.0 ± 0.0
2.983GluTyr: 2.983 ± 0.959
0.0GluXaa: 0.0 ± 0.0
Phe
5.22PheAla: 5.22 ± 1.778
0.746PheCys: 0.746 ± 0.506
2.237PheAsp: 2.237 ± 0.453
1.491PheGlu: 1.491 ± 0.052
4.474PhePhe: 4.474 ± 1.97
3.729PheGly: 3.729 ± 0.401
1.491PheHis: 1.491 ± 1.011
3.729PheIle: 3.729 ± 0.401
2.237PheLys: 2.237 ± 0.453
11.186PheLeu: 11.186 ± 1.203
1.491PheMet: 1.491 ± 0.052
2.983PheAsn: 2.983 ± 1.168
4.474PhePro: 4.474 ± 1.97
2.237PheGln: 2.237 ± 0.453
2.237PheArg: 2.237 ± 0.61
2.237PheSer: 2.237 ± 0.61
4.474PheThr: 4.474 ± 1.97
1.491PheVal: 1.491 ± 0.052
0.0PheTrp: 0.0 ± 0.0
2.983PheTyr: 2.983 ± 0.105
0.0PheXaa: 0.0 ± 0.0
Gly
2.983GlyAla: 2.983 ± 0.105
0.0GlyCys: 0.0 ± 0.0
1.491GlyAsp: 1.491 ± 0.052
0.746GlyGlu: 0.746 ± 0.558
4.474GlyPhe: 4.474 ± 0.157
0.0GlyGly: 0.0 ± 0.0
2.237GlyHis: 2.237 ± 1.674
2.237GlyIle: 2.237 ± 0.61
0.746GlyLys: 0.746 ± 0.558
2.237GlyLeu: 2.237 ± 0.61
1.491GlyMet: 1.491 ± 1.011
4.474GlyAsn: 4.474 ± 1.22
0.746GlyPro: 0.746 ± 0.506
0.0GlyGln: 0.0 ± 0.0
2.983GlyArg: 2.983 ± 1.168
2.983GlySer: 2.983 ± 1.168
4.474GlyThr: 4.474 ± 1.22
0.746GlyVal: 0.746 ± 0.506
0.0GlyTrp: 0.0 ± 0.0
5.22GlyTyr: 5.22 ± 2.475
0.0GlyXaa: 0.0 ± 0.0
His
1.491HisAla: 1.491 ± 0.052
0.0HisCys: 0.0 ± 0.0
2.237HisAsp: 2.237 ± 0.61
1.491HisGlu: 1.491 ± 1.011
2.237HisPhe: 2.237 ± 0.453
2.237HisGly: 2.237 ± 0.61
1.491HisHis: 1.491 ± 1.116
2.237HisIle: 2.237 ± 0.453
1.491HisLys: 1.491 ± 0.052
3.729HisLeu: 3.729 ± 0.663
1.491HisMet: 1.491 ± 1.419
1.491HisAsn: 1.491 ± 1.116
2.237HisPro: 2.237 ± 0.453
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.237HisSer: 2.237 ± 0.453
2.237HisThr: 2.237 ± 0.61
4.474HisVal: 4.474 ± 1.97
0.746HisTrp: 0.746 ± 0.506
2.237HisTyr: 2.237 ± 0.61
0.0HisXaa: 0.0 ± 0.0
Ile
5.22IleAla: 5.22 ± 0.715
0.0IleCys: 0.0 ± 0.0
5.966IleAsp: 5.966 ± 0.854
3.729IleGlu: 3.729 ± 0.663
1.491IlePhe: 1.491 ± 0.052
0.746IleGly: 0.746 ± 0.558
3.729IleHis: 3.729 ± 0.401
1.491IleIle: 1.491 ± 0.052
2.237IleLys: 2.237 ± 0.453
4.474IleLeu: 4.474 ± 0.157
2.983IleMet: 2.983 ± 0.105
2.237IleAsn: 2.237 ± 1.517
2.983IlePro: 2.983 ± 0.105
3.729IleGln: 3.729 ± 1.464
3.729IleArg: 3.729 ± 0.663
2.237IleSer: 2.237 ± 0.453
3.729IleThr: 3.729 ± 1.464
1.491IleVal: 1.491 ± 0.052
0.746IleTrp: 0.746 ± 0.506
1.491IleTyr: 1.491 ± 0.052
0.0IleXaa: 0.0 ± 0.0
Lys
1.491LysAla: 1.491 ± 1.116
0.0LysCys: 0.0 ± 0.0
2.983LysAsp: 2.983 ± 0.105
0.746LysGlu: 0.746 ± 0.506
2.237LysPhe: 2.237 ± 0.61
1.491LysGly: 1.491 ± 0.052
2.237LysHis: 2.237 ± 0.453
3.729LysIle: 3.729 ± 0.401
2.983LysLys: 2.983 ± 1.168
2.237LysLeu: 2.237 ± 0.453
1.491LysMet: 1.491 ± 1.011
1.491LysAsn: 1.491 ± 1.116
2.237LysPro: 2.237 ± 1.517
1.491LysGln: 1.491 ± 0.052
2.983LysArg: 2.983 ± 2.022
2.983LysSer: 2.983 ± 0.105
1.491LysThr: 1.491 ± 1.011
1.491LysVal: 1.491 ± 0.052
0.746LysTrp: 0.746 ± 0.506
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
11.186LeuAla: 11.186 ± 5.178
0.0LeuCys: 0.0 ± 0.0
5.22LeuAsp: 5.22 ± 0.715
5.966LeuGlu: 5.966 ± 2.981
5.966LeuPhe: 5.966 ± 0.854
4.474LeuGly: 4.474 ± 1.22
1.491LeuHis: 1.491 ± 0.052
2.983LeuIle: 2.983 ± 2.022
1.491LeuLys: 1.491 ± 1.011
11.931LeuLeu: 11.931 ± 0.645
1.491LeuMet: 1.491 ± 1.116
5.966LeuAsn: 5.966 ± 2.336
7.457LeuPro: 7.457 ± 1.865
3.729LeuGln: 3.729 ± 0.663
3.729LeuArg: 3.729 ± 1.464
11.931LeuSer: 11.931 ± 1.708
5.966LeuThr: 5.966 ± 1.273
5.22LeuVal: 5.22 ± 2.475
0.746LeuTrp: 0.746 ± 0.558
2.983LeuTyr: 2.983 ± 1.168
0.0LeuXaa: 0.0 ± 0.0
Met
2.237MetAla: 2.237 ± 0.453
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.746MetPhe: 0.746 ± 0.506
0.746MetGly: 0.746 ± 0.506
0.0MetHis: 0.0 ± 0.0
1.491MetIle: 1.491 ± 0.052
0.746MetLys: 0.746 ± 0.506
3.729MetLeu: 3.729 ± 0.663
0.746MetMet: 0.746 ± 0.506
1.491MetAsn: 1.491 ± 0.052
0.746MetPro: 0.746 ± 0.558
1.491MetGln: 1.491 ± 0.052
0.0MetArg: 0.0 ± 0.0
2.983MetSer: 2.983 ± 0.105
2.237MetThr: 2.237 ± 1.674
2.237MetVal: 2.237 ± 1.517
0.0MetTrp: 0.0 ± 0.0
2.983MetTyr: 2.983 ± 0.105
0.0MetXaa: 0.0 ± 0.0
Asn
4.474AsnAla: 4.474 ± 2.284
0.746AsnCys: 0.746 ± 0.558
3.729AsnAsp: 3.729 ± 1.726
0.0AsnGlu: 0.0 ± 0.0
3.729AsnPhe: 3.729 ± 0.663
0.746AsnGly: 0.746 ± 0.558
1.491AsnHis: 1.491 ± 1.011
3.729AsnIle: 3.729 ± 0.401
2.983AsnLys: 2.983 ± 0.105
2.983AsnLeu: 2.983 ± 1.168
1.491AsnMet: 1.491 ± 0.052
2.237AsnAsn: 2.237 ± 1.674
3.729AsnPro: 3.729 ± 1.726
1.491AsnGln: 1.491 ± 1.011
2.983AsnArg: 2.983 ± 0.959
2.237AsnSer: 2.237 ± 1.517
2.983AsnThr: 2.983 ± 0.105
5.22AsnVal: 5.22 ± 0.715
0.746AsnTrp: 0.746 ± 0.558
1.491AsnTyr: 1.491 ± 1.116
0.0AsnXaa: 0.0 ± 0.0
Pro
6.711ProAla: 6.711 ± 1.831
0.0ProCys: 0.0 ± 0.0
4.474ProAsp: 4.474 ± 0.906
4.474ProGlu: 4.474 ± 0.906
0.746ProPhe: 0.746 ± 0.506
0.746ProGly: 0.746 ± 0.506
1.491ProHis: 1.491 ± 0.052
2.237ProIle: 2.237 ± 1.517
2.983ProLys: 2.983 ± 0.105
4.474ProLeu: 4.474 ± 0.906
0.0ProMet: 0.0 ± 0.0
0.746ProAsn: 0.746 ± 0.558
3.729ProPro: 3.729 ± 1.726
2.237ProGln: 2.237 ± 1.517
2.983ProArg: 2.983 ± 0.105
7.457ProSer: 7.457 ± 0.802
5.22ProThr: 5.22 ± 1.778
5.966ProVal: 5.966 ± 2.336
0.746ProTrp: 0.746 ± 0.506
6.711ProTyr: 6.711 ± 1.831
0.0ProXaa: 0.0 ± 0.0
Gln
0.746GlnAla: 0.746 ± 0.506
0.0GlnCys: 0.0 ± 0.0
2.237GlnAsp: 2.237 ± 0.453
2.237GlnGlu: 2.237 ± 0.61
3.729GlnPhe: 3.729 ± 1.464
2.237GlnGly: 2.237 ± 0.61
2.237GlnHis: 2.237 ± 1.517
0.746GlnIle: 0.746 ± 0.558
0.746GlnLys: 0.746 ± 0.506
2.237GlnLeu: 2.237 ± 0.453
0.0GlnMet: 0.0 ± 0.0
0.746GlnAsn: 0.746 ± 0.506
2.983GlnPro: 2.983 ± 0.105
0.746GlnGln: 0.746 ± 0.558
5.22GlnArg: 5.22 ± 1.412
2.983GlnSer: 2.983 ± 0.959
2.983GlnThr: 2.983 ± 0.959
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.237GlnTyr: 2.237 ± 1.517
0.0GlnXaa: 0.0 ± 0.0
Arg
0.746ArgAla: 0.746 ± 0.506
0.0ArgCys: 0.0 ± 0.0
2.983ArgAsp: 2.983 ± 0.105
2.237ArgGlu: 2.237 ± 0.453
2.983ArgPhe: 2.983 ± 1.168
0.746ArgGly: 0.746 ± 0.506
0.746ArgHis: 0.746 ± 0.506
2.983ArgIle: 2.983 ± 0.105
1.491ArgLys: 1.491 ± 0.052
8.203ArgLeu: 8.203 ± 4.497
0.746ArgMet: 0.746 ± 0.558
2.237ArgAsn: 2.237 ± 0.61
5.22ArgPro: 5.22 ± 2.475
0.0ArgGln: 0.0 ± 0.0
2.237ArgArg: 2.237 ± 0.453
5.22ArgSer: 5.22 ± 0.349
6.711ArgThr: 6.711 ± 1.831
3.729ArgVal: 3.729 ± 0.663
0.746ArgTrp: 0.746 ± 0.506
3.729ArgTyr: 3.729 ± 0.401
0.0ArgXaa: 0.0 ± 0.0
Ser
4.474SerAla: 4.474 ± 0.157
0.746SerCys: 0.746 ± 0.506
3.729SerAsp: 3.729 ± 0.663
0.0SerGlu: 0.0 ± 0.0
4.474SerPhe: 4.474 ± 1.97
5.22SerGly: 5.22 ± 0.349
2.983SerHis: 2.983 ± 2.022
5.966SerIle: 5.966 ± 0.854
4.474SerLys: 4.474 ± 1.97
8.203SerLeu: 8.203 ± 0.82
1.491SerMet: 1.491 ± 0.052
5.22SerAsn: 5.22 ± 0.349
2.983SerPro: 2.983 ± 2.231
0.746SerGln: 0.746 ± 0.506
5.966SerArg: 5.966 ± 0.854
3.729SerSer: 3.729 ± 1.726
2.237SerThr: 2.237 ± 0.61
2.983SerVal: 2.983 ± 1.168
0.746SerTrp: 0.746 ± 0.558
5.966SerTyr: 5.966 ± 0.854
0.0SerXaa: 0.0 ± 0.0
Thr
8.203ThrAla: 8.203 ± 4.01
0.746ThrCys: 0.746 ± 0.506
4.474ThrAsp: 4.474 ± 0.157
3.729ThrGlu: 3.729 ± 0.663
7.457ThrPhe: 7.457 ± 1.325
2.983ThrGly: 2.983 ± 0.959
0.0ThrHis: 0.0 ± 0.0
5.22ThrIle: 5.22 ± 0.349
2.237ThrLys: 2.237 ± 0.453
8.203ThrLeu: 8.203 ± 2.946
1.491ThrMet: 1.491 ± 1.011
4.474ThrAsn: 4.474 ± 1.22
5.22ThrPro: 5.22 ± 1.778
3.729ThrGln: 3.729 ± 0.401
4.474ThrArg: 4.474 ± 0.157
1.491ThrSer: 1.491 ± 0.052
6.711ThrThr: 6.711 ± 0.296
1.491ThrVal: 1.491 ± 1.011
2.237ThrTrp: 2.237 ± 0.61
2.237ThrTyr: 2.237 ± 0.61
0.0ThrXaa: 0.0 ± 0.0
Val
0.746ValAla: 0.746 ± 0.506
0.0ValCys: 0.0 ± 0.0
3.729ValAsp: 3.729 ± 2.528
1.491ValGlu: 1.491 ± 1.116
4.474ValPhe: 4.474 ± 0.906
1.491ValGly: 1.491 ± 0.052
1.491ValHis: 1.491 ± 0.052
3.729ValIle: 3.729 ± 0.401
1.491ValLys: 1.491 ± 0.052
5.22ValLeu: 5.22 ± 0.715
3.729ValMet: 3.729 ± 0.401
2.237ValAsn: 2.237 ± 1.674
4.474ValPro: 4.474 ± 0.906
2.237ValGln: 2.237 ± 0.61
2.237ValArg: 2.237 ± 1.517
3.729ValSer: 3.729 ± 0.663
5.22ValThr: 5.22 ± 0.349
2.237ValVal: 2.237 ± 0.61
0.0ValTrp: 0.0 ± 0.0
2.983ValTyr: 2.983 ± 0.105
0.0ValXaa: 0.0 ± 0.0
Trp
0.746TrpAla: 0.746 ± 0.506
0.0TrpCys: 0.0 ± 0.0
0.746TrpAsp: 0.746 ± 0.506
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.746TrpHis: 0.746 ± 0.558
1.491TrpIle: 1.491 ± 1.011
0.0TrpLys: 0.0 ± 0.0
0.746TrpLeu: 0.746 ± 0.558
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.746TrpGln: 0.746 ± 0.506
0.0TrpArg: 0.0 ± 0.0
2.237TrpSer: 2.237 ± 0.453
0.746TrpThr: 0.746 ± 0.558
0.746TrpVal: 0.746 ± 0.506
0.0TrpTrp: 0.0 ± 0.0
1.491TrpTyr: 1.491 ± 0.052
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.474TyrAla: 4.474 ± 0.157
0.746TyrCys: 0.746 ± 0.558
3.729TyrAsp: 3.729 ± 0.401
3.729TyrGlu: 3.729 ± 1.464
2.983TyrPhe: 2.983 ± 1.168
2.983TyrGly: 2.983 ± 0.959
2.983TyrHis: 2.983 ± 2.231
2.237TyrIle: 2.237 ± 0.61
2.237TyrLys: 2.237 ± 0.61
5.966TyrLeu: 5.966 ± 0.854
0.746TyrMet: 0.746 ± 0.506
2.237TyrAsn: 2.237 ± 1.517
2.983TyrPro: 2.983 ± 0.959
2.237TyrGln: 2.237 ± 1.517
0.746TyrArg: 0.746 ± 0.558
2.983TyrSer: 2.983 ± 0.105
3.729TyrThr: 3.729 ± 1.726
2.983TyrVal: 2.983 ± 0.105
0.0TyrTrp: 0.0 ± 0.0
1.491TyrTyr: 1.491 ± 1.011
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1342 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski