Amino acid dipepetide frequency for Corynebacterium aquilae DSM 44791

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.023AlaAla: 16.023 ± 0.28	1.179AlaCys: 1.179 ± 0.045	7.403AlaAsp: 7.403 ± 0.14	7.499AlaGlu: 7.499 ± 0.115	3.558AlaPhe: 3.558 ± 0.078	10.243AlaGly: 10.243 ± 0.142	2.969AlaHis: 2.969 ± 0.074	5.94AlaIle: 5.94 ± 0.12	4.074AlaLys: 4.074 ± 0.11	11.495AlaLeu: 11.495 ± 0.156	2.776AlaMet: 2.776 ± 0.059	2.985AlaAsn: 2.985 ± 0.067	5.506AlaPro: 5.506 ± 0.15	4.874AlaGln: 4.874 ± 0.107	7.162AlaArg: 7.162 ± 0.127	5.866AlaSer: 5.866 ± 0.115	7.884AlaThr: 7.884 ± 0.13	9.407AlaVal: 9.407 ± 0.159	1.374AlaTrp: 1.374 ± 0.05	2.338AlaTyr: 2.338 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.156CysAla: 1.156 ± 0.053	0.11CysCys: 0.11 ± 0.013	0.569CysAsp: 0.569 ± 0.03	0.534CysGlu: 0.534 ± 0.033	0.284CysPhe: 0.284 ± 0.021	0.946CysGly: 0.946 ± 0.042	0.226CysHis: 0.226 ± 0.018	0.354CysIle: 0.354 ± 0.023	0.201CysLys: 0.201 ± 0.019	0.694CysLeu: 0.694 ± 0.037	0.153CysMet: 0.153 ± 0.016	0.218CysAsn: 0.218 ± 0.019	0.505CysPro: 0.505 ± 0.028	0.284CysGln: 0.284 ± 0.019	0.424CysArg: 0.424 ± 0.028	0.468CysSer: 0.468 ± 0.029	0.538CysThr: 0.538 ± 0.032	0.723CysVal: 0.723 ± 0.035	0.11CysTrp: 0.11 ± 0.012	0.181CysTyr: 0.181 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.301AspAla: 7.301 ± 0.111	0.58AspCys: 0.58 ± 0.033	3.776AspAsp: 3.776 ± 0.101	4.354AspGlu: 4.354 ± 0.096	2.161AspPhe: 2.161 ± 0.062	5.128AspGly: 5.128 ± 0.106	1.42AspHis: 1.42 ± 0.054	3.424AspIle: 3.424 ± 0.074	2.239AspLys: 2.239 ± 0.078	5.222AspLeu: 5.222 ± 0.093	1.312AspMet: 1.312 ± 0.041	2.073AspAsn: 2.073 ± 0.068	3.727AspPro: 3.727 ± 0.072	1.696AspGln: 1.696 ± 0.052	3.12AspArg: 3.12 ± 0.084	3.217AspSer: 3.217 ± 0.08	3.714AspThr: 3.714 ± 0.088	5.099AspVal: 5.099 ± 0.099	0.75AspTrp: 0.75 ± 0.035	1.543AspTyr: 1.543 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	6.502GluAla: 6.502 ± 0.128	0.442GluCys: 0.442 ± 0.029	3.729GluAsp: 3.729 ± 0.085	3.718GluGlu: 3.718 ± 0.096	2.018GluPhe: 2.018 ± 0.054	4.042GluGly: 4.042 ± 0.083	1.588GluHis: 1.588 ± 0.047	3.012GluIle: 3.012 ± 0.077	2.675GluLys: 2.675 ± 0.071	6.342GluLeu: 6.342 ± 0.1	1.309GluMet: 1.309 ± 0.05	1.877GluAsn: 1.877 ± 0.066	2.544GluPro: 2.544 ± 0.072	2.846GluGln: 2.846 ± 0.078	3.537GluArg: 3.537 ± 0.089	2.539GluSer: 2.539 ± 0.07	2.931GluThr: 2.931 ± 0.07	4.606GluVal: 4.606 ± 0.093	0.662GluTrp: 0.662 ± 0.038	1.469GluTyr: 1.469 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.926PheAla: 3.926 ± 0.087	0.265PheCys: 0.265 ± 0.022	2.507PheAsp: 2.507 ± 0.067	1.833PheGlu: 1.833 ± 0.052	1.321PhePhe: 1.321 ± 0.048	3.383PheGly: 3.383 ± 0.078	0.699PheHis: 0.699 ± 0.037	1.652PheIle: 1.652 ± 0.062	0.813PheLys: 0.813 ± 0.044	2.773PheLeu: 2.773 ± 0.084	0.628PheMet: 0.628 ± 0.037	1.036PheAsn: 1.036 ± 0.044	1.478PhePro: 1.478 ± 0.052	0.808PheGln: 0.808 ± 0.034	1.489PheArg: 1.489 ± 0.051	2.128PheSer: 2.128 ± 0.061	2.201PheThr: 2.201 ± 0.057	2.818PheVal: 2.818 ± 0.068	0.355PheTrp: 0.355 ± 0.026	0.856PheTyr: 0.856 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	8.757GlyAla: 8.757 ± 0.138	0.843GlyCys: 0.843 ± 0.042	4.53GlyAsp: 4.53 ± 0.102	4.945GlyGlu: 4.945 ± 0.098	3.207GlyPhe: 3.207 ± 0.078	6.769GlyGly: 6.769 ± 0.143	2.021GlyHis: 2.021 ± 0.059	4.504GlyIle: 4.504 ± 0.094	3.163GlyLys: 3.163 ± 0.082	7.778GlyLeu: 7.778 ± 0.137	2.216GlyMet: 2.216 ± 0.063	2.228GlyAsn: 2.228 ± 0.062	3.22GlyPro: 3.22 ± 0.071	3.053GlyGln: 3.053 ± 0.058	4.757GlyArg: 4.757 ± 0.091	4.659GlySer: 4.659 ± 0.086	5.149GlyThr: 5.149 ± 0.1	7.351GlyVal: 7.351 ± 0.137	1.304GlyTrp: 1.304 ± 0.041	2.196GlyTyr: 2.196 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	2.506HisAla: 2.506 ± 0.071	0.233HisCys: 0.233 ± 0.02	1.396HisAsp: 1.396 ± 0.049	1.18HisGlu: 1.18 ± 0.048	0.694HisPhe: 0.694 ± 0.034	1.897HisGly: 1.897 ± 0.061	0.819HisHis: 0.819 ± 0.042	1.153HisIle: 1.153 ± 0.042	0.583HisLys: 0.583 ± 0.03	2.146HisLeu: 2.146 ± 0.062	0.519HisMet: 0.519 ± 0.032	0.767HisAsn: 0.767 ± 0.033	1.719HisPro: 1.719 ± 0.063	0.805HisGln: 0.805 ± 0.038	1.464HisArg: 1.464 ± 0.051	1.228HisSer: 1.228 ± 0.048	1.737HisThr: 1.737 ± 0.055	1.644HisVal: 1.644 ± 0.05	0.279HisTrp: 0.279 ± 0.022	0.586HisTyr: 0.586 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.906IleAla: 6.906 ± 0.132	0.406IleCys: 0.406 ± 0.026	3.938IleAsp: 3.938 ± 0.082	2.898IleGlu: 2.898 ± 0.075	1.559IlePhe: 1.559 ± 0.058	4.507IleGly: 4.507 ± 0.103	1.023IleHis: 1.023 ± 0.035	2.835IleIle: 2.835 ± 0.084	1.575IleLys: 1.575 ± 0.056	3.949IleLeu: 3.949 ± 0.091	0.949IleMet: 0.949 ± 0.043	1.711IleAsn: 1.711 ± 0.051	2.695IlePro: 2.695 ± 0.06	1.199IleGln: 1.199 ± 0.044	2.504IleArg: 2.504 ± 0.067	2.818IleSer: 2.818 ± 0.071	3.66IleThr: 3.66 ± 0.092	4.522IleVal: 4.522 ± 0.104	0.386IleTrp: 0.386 ± 0.026	1.023IleTyr: 1.023 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.179LysAla: 4.179 ± 0.119	0.16LysCys: 0.16 ± 0.017	2.402LysAsp: 2.402 ± 0.075	1.993LysGlu: 1.993 ± 0.076	0.878LysPhe: 0.878 ± 0.039	2.413LysGly: 2.413 ± 0.07	0.72LysHis: 0.72 ± 0.035	1.774LysIle: 1.774 ± 0.063	1.911LysLys: 1.911 ± 0.067	3.163LysLeu: 3.163 ± 0.082	0.862LysMet: 0.862 ± 0.033	1.283LysAsn: 1.283 ± 0.047	1.874LysPro: 1.874 ± 0.07	1.382LysGln: 1.382 ± 0.047	1.984LysArg: 1.984 ± 0.066	1.559LysSer: 1.559 ± 0.057	2.147LysThr: 2.147 ± 0.071	2.82LysVal: 2.82 ± 0.084	0.372LysTrp: 0.372 ± 0.026	0.694LysTyr: 0.694 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	12.105LeuAla: 12.105 ± 0.166	0.793LeuCys: 0.793 ± 0.037	5.858LeuAsp: 5.858 ± 0.118	4.765LeuGlu: 4.765 ± 0.107	2.686LeuPhe: 2.686 ± 0.071	8.125LeuGly: 8.125 ± 0.127	1.879LeuHis: 1.879 ± 0.053	4.887LeuIle: 4.887 ± 0.109	3.2LeuLys: 3.2 ± 0.087	8.509LeuLeu: 8.509 ± 0.161	1.983LeuMet: 1.983 ± 0.058	2.761LeuAsn: 2.761 ± 0.069	5.225LeuPro: 5.225 ± 0.097	2.446LeuGln: 2.446 ± 0.067	5.401LeuArg: 5.401 ± 0.103	5.887LeuSer: 5.887 ± 0.119	5.901LeuThr: 5.901 ± 0.095	7.516LeuVal: 7.516 ± 0.126	1.156LeuTrp: 1.156 ± 0.048	1.713LeuTyr: 1.713 ± 0.05	0.002LeuXaa: 0.002 ± 0.001
Met	2.722MetAla: 2.722 ± 0.059	0.195MetCys: 0.195 ± 0.016	1.124MetAsp: 1.124 ± 0.042	1.081MetGlu: 1.081 ± 0.048	0.752MetPhe: 0.752 ± 0.035	1.835MetGly: 1.835 ± 0.059	0.433MetHis: 0.433 ± 0.027	1.168MetIle: 1.168 ± 0.048	0.816MetLys: 0.816 ± 0.031	2.163MetLeu: 2.163 ± 0.062	0.525MetMet: 0.525 ± 0.029	0.7MetAsn: 0.7 ± 0.035	1.179MetPro: 1.179 ± 0.043	0.605MetGln: 0.605 ± 0.03	1.495MetArg: 1.495 ± 0.052	1.609MetSer: 1.609 ± 0.049	1.698MetThr: 1.698 ± 0.046	1.789MetVal: 1.789 ± 0.054	0.265MetTrp: 0.265 ± 0.022	0.4MetTyr: 0.4 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.171AsnAla: 3.171 ± 0.073	0.241AsnCys: 0.241 ± 0.022	1.63AsnAsp: 1.63 ± 0.057	1.467AsnGlu: 1.467 ± 0.051	0.901AsnPhe: 0.901 ± 0.045	2.253AsnGly: 2.253 ± 0.08	0.735AsnHis: 0.735 ± 0.035	1.53AsnIle: 1.53 ± 0.05	1.159AsnLys: 1.159 ± 0.051	2.736AsnLeu: 2.736 ± 0.07	0.659AsnMet: 0.659 ± 0.028	1.126AsnAsn: 1.126 ± 0.058	2.305AsnPro: 2.305 ± 0.054	1.016AsnGln: 1.016 ± 0.04	1.6AsnArg: 1.6 ± 0.051	1.665AsnSer: 1.665 ± 0.054	2.035AsnThr: 2.035 ± 0.066	2.225AsnVal: 2.225 ± 0.07	0.393AsnTrp: 0.393 ± 0.023	0.796AsnTyr: 0.796 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	6.703ProAla: 6.703 ± 0.152	0.302ProCys: 0.302 ± 0.023	3.366ProAsp: 3.366 ± 0.078	3.86ProGlu: 3.86 ± 0.071	1.635ProPhe: 1.635 ± 0.047	4.571ProGly: 4.571 ± 0.095	1.33ProHis: 1.33 ± 0.052	2.23ProIle: 2.23 ± 0.06	1.751ProLys: 1.751 ± 0.059	4.405ProLeu: 4.405 ± 0.09	1.051ProMet: 1.051 ± 0.039	1.626ProAsn: 1.626 ± 0.051	2.123ProPro: 2.123 ± 0.084	2.112ProGln: 2.112 ± 0.065	2.631ProArg: 2.631 ± 0.06	2.664ProSer: 2.664 ± 0.06	3.778ProThr: 3.778 ± 0.093	4.4ProVal: 4.4 ± 0.106	0.683ProTrp: 0.683 ± 0.034	1.068ProTyr: 1.068 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.618GlnAla: 4.618 ± 0.099	0.232GlnCys: 0.232 ± 0.022	1.676GlnAsp: 1.676 ± 0.057	1.943GlnGlu: 1.943 ± 0.061	1.005GlnPhe: 1.005 ± 0.043	2.384GlnGly: 2.384 ± 0.059	0.921GlnHis: 0.921 ± 0.04	1.498GlnIle: 1.498 ± 0.054	1.055GlnLys: 1.055 ± 0.047	4.081GlnLeu: 4.081 ± 0.084	0.779GlnMet: 0.779 ± 0.037	0.76GlnAsn: 0.76 ± 0.039	2.227GlnPro: 2.227 ± 0.075	1.913GlnGln: 1.913 ± 0.085	2.599GlnArg: 2.599 ± 0.067	1.461GlnSer: 1.461 ± 0.048	1.508GlnThr: 1.508 ± 0.051	2.603GlnVal: 2.603 ± 0.073	0.607GlnTrp: 0.607 ± 0.032	0.65GlnTyr: 0.65 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	6.371ArgAla: 6.371 ± 0.102	0.444ArgCys: 0.444 ± 0.025	3.511ArgAsp: 3.511 ± 0.09	3.607ArgGlu: 3.607 ± 0.081	2.018ArgPhe: 2.018 ± 0.065	4.316ArgGly: 4.316 ± 0.078	1.367ArgHis: 1.367 ± 0.047	3.13ArgIle: 3.13 ± 0.07	1.971ArgLys: 1.971 ± 0.062	5.413ArgLeu: 5.413 ± 0.111	1.531ArgMet: 1.531 ± 0.052	1.707ArgAsn: 1.707 ± 0.049	2.838ArgPro: 2.838 ± 0.075	2.161ArgGln: 2.161 ± 0.061	4.284ArgArg: 4.284 ± 0.09	2.918ArgSer: 2.918 ± 0.083	3.583ArgThr: 3.583 ± 0.093	4.312ArgVal: 4.312 ± 0.091	0.793ArgTrp: 0.793 ± 0.038	1.492ArgTyr: 1.492 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	6.072SerAla: 6.072 ± 0.107	0.474SerCys: 0.474 ± 0.023	3.122SerAsp: 3.122 ± 0.077	2.733SerGlu: 2.733 ± 0.069	2.08SerPhe: 2.08 ± 0.06	5.051SerGly: 5.051 ± 0.103	1.165SerHis: 1.165 ± 0.046	2.512SerIle: 2.512 ± 0.067	1.746SerLys: 1.746 ± 0.06	4.992SerLeu: 4.992 ± 0.094	1.431SerMet: 1.431 ± 0.046	1.569SerAsn: 1.569 ± 0.048	2.913SerPro: 2.913 ± 0.06	1.858SerGln: 1.858 ± 0.058	3.163SerArg: 3.163 ± 0.068	3.392SerSer: 3.392 ± 0.084	3.79SerThr: 3.79 ± 0.085	4.199SerVal: 4.199 ± 0.094	0.828SerTrp: 0.828 ± 0.037	1.272SerTyr: 1.272 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	7.365ThrAla: 7.365 ± 0.116	0.595ThrCys: 0.595 ± 0.04	3.442ThrAsp: 3.442 ± 0.066	2.936ThrGlu: 2.936 ± 0.07	2.152ThrPhe: 2.152 ± 0.055	5.431ThrGly: 5.431 ± 0.111	1.679ThrHis: 1.679 ± 0.059	3.663ThrIle: 3.663 ± 0.087	2.099ThrLys: 2.099 ± 0.061	5.719ThrLeu: 5.719 ± 0.089	1.423ThrMet: 1.423 ± 0.045	1.893ThrAsn: 1.893 ± 0.08	4.406ThrPro: 4.406 ± 0.115	2.025ThrGln: 2.025 ± 0.064	3.364ThrArg: 3.364 ± 0.075	3.621ThrSer: 3.621 ± 0.084	4.999ThrThr: 4.999 ± 0.13	5.57ThrVal: 5.57 ± 0.108	0.877ThrTrp: 0.877 ± 0.034	1.466ThrTyr: 1.466 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	10.309ValAla: 10.309 ± 0.167	0.842ValCys: 0.842 ± 0.039	5.802ValAsp: 5.802 ± 0.096	5.085ValGlu: 5.085 ± 0.102	2.785ValPhe: 2.785 ± 0.076	6.506ValGly: 6.506 ± 0.107	1.673ValHis: 1.673 ± 0.05	4.229ValIle: 4.229 ± 0.09	2.527ValLys: 2.527 ± 0.069	7.62ValLeu: 7.62 ± 0.118	1.748ValMet: 1.748 ± 0.052	2.253ValAsn: 2.253 ± 0.063	3.962ValPro: 3.962 ± 0.079	2.004ValGln: 2.004 ± 0.056	4.487ValArg: 4.487 ± 0.084	4.701ValSer: 4.701 ± 0.087	5.303ValThr: 5.303 ± 0.133	7.885ValVal: 7.885 ± 0.124	0.973ValTrp: 0.973 ± 0.042	1.595ValTyr: 1.595 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	1.348TrpAla: 1.348 ± 0.05	0.142TrpCys: 0.142 ± 0.015	0.705TrpAsp: 0.705 ± 0.034	0.721TrpGlu: 0.721 ± 0.041	0.497TrpPhe: 0.497 ± 0.029	0.872TrpGly: 0.872 ± 0.038	0.268TrpHis: 0.268 ± 0.019	0.627TrpIle: 0.627 ± 0.033	0.4TrpLys: 0.4 ± 0.026	1.458TrpLeu: 1.458 ± 0.058	0.348TrpMet: 0.348 ± 0.024	0.381TrpAsn: 0.381 ± 0.026	0.604TrpPro: 0.604 ± 0.031	0.549TrpGln: 0.549 ± 0.027	0.863TrpArg: 0.863 ± 0.037	0.674TrpSer: 0.674 ± 0.032	0.647TrpThr: 0.647 ± 0.036	1.095TrpVal: 1.095 ± 0.043	0.314TrpTrp: 0.314 ± 0.024	0.271TrpTyr: 0.271 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.517TyrAla: 2.517 ± 0.057	0.198TyrCys: 0.198 ± 0.017	1.37TyrAsp: 1.37 ± 0.047	1.234TyrGlu: 1.234 ± 0.046	0.776TyrPhe: 0.776 ± 0.031	1.981TyrGly: 1.981 ± 0.058	0.419TyrHis: 0.419 ± 0.026	0.943TyrIle: 0.943 ± 0.038	0.613TyrLys: 0.613 ± 0.036	2.138TyrLeu: 2.138 ± 0.058	0.354TyrMet: 0.354 ± 0.025	0.691TyrAsn: 0.691 ± 0.038	1.24TyrPro: 1.24 ± 0.048	0.883TyrGln: 0.883 ± 0.035	1.435TyrArg: 1.435 ± 0.052	1.289TyrSer: 1.289 ± 0.04	1.524TyrThr: 1.524 ± 0.051	1.704TyrVal: 1.704 ± 0.049	0.3TyrTrp: 0.3 ± 0.022	0.578TyrTyr: 0.578 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.002XaaTrp: 0.002 ± 0.001	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2002 proteins (655671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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