Amino acid dipepetide frequency for Rosa chinensis (China rose)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.778AlaAla: 5.778 ± 0.029	1.262AlaCys: 1.262 ± 0.01	2.942AlaAsp: 2.942 ± 0.017	3.89AlaGlu: 3.89 ± 0.021	2.744AlaPhe: 2.744 ± 0.016	3.878AlaGly: 3.878 ± 0.019	1.298AlaHis: 1.298 ± 0.009	3.655AlaIle: 3.655 ± 0.017	3.713AlaLys: 3.713 ± 0.019	6.527AlaLeu: 6.527 ± 0.024	1.727AlaMet: 1.727 ± 0.012	2.511AlaAsn: 2.511 ± 0.012	2.66AlaPro: 2.66 ± 0.018	2.064AlaGln: 2.064 ± 0.012	3.192AlaArg: 3.192 ± 0.015	5.603AlaSer: 5.603 ± 0.024	3.464AlaThr: 3.464 ± 0.018	4.562AlaVal: 4.562 ± 0.021	0.796AlaTrp: 0.796 ± 0.009	1.801AlaTyr: 1.801 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	0.999CysAla: 0.999 ± 0.009	0.632CysCys: 0.632 ± 0.008	0.907CysAsp: 0.907 ± 0.008	0.928CysGlu: 0.928 ± 0.009	1.069CysPhe: 1.069 ± 0.009	1.466CysGly: 1.466 ± 0.012	0.519CysHis: 0.519 ± 0.005	1.108CysIle: 1.108 ± 0.009	1.258CysLys: 1.258 ± 0.01	2.155CysLeu: 2.155 ± 0.014	0.522CysMet: 0.522 ± 0.006	0.958CysAsn: 0.958 ± 0.009	0.957CysPro: 0.957 ± 0.011	0.659CysGln: 0.659 ± 0.007	1.095CysArg: 1.095 ± 0.01	1.99CysSer: 1.99 ± 0.014	0.961CysThr: 0.961 ± 0.01	1.143CysVal: 1.143 ± 0.01	0.303CysTrp: 0.303 ± 0.005	0.582CysTyr: 0.582 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.209AspAla: 3.209 ± 0.015	1.037AspCys: 1.037 ± 0.01	3.414AspAsp: 3.414 ± 0.022	3.73AspGlu: 3.73 ± 0.02	2.39AspPhe: 2.39 ± 0.013	3.636AspGly: 3.636 ± 0.018	1.281AspHis: 1.281 ± 0.011	2.982AspIle: 2.982 ± 0.017	2.606AspLys: 2.606 ± 0.015	5.311AspLeu: 5.311 ± 0.021	1.366AspMet: 1.366 ± 0.01	1.974AspAsn: 1.974 ± 0.01	2.467AspPro: 2.467 ± 0.014	1.792AspGln: 1.792 ± 0.012	2.298AspArg: 2.298 ± 0.015	3.966AspSer: 3.966 ± 0.019	2.119AspThr: 2.119 ± 0.013	3.586AspVal: 3.586 ± 0.016	0.754AspTrp: 0.754 ± 0.008	1.571AspTyr: 1.571 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	4.535GluAla: 4.535 ± 0.024	0.949GluCys: 0.949 ± 0.01	3.79GluAsp: 3.79 ± 0.022	5.78GluGlu: 5.78 ± 0.036	2.421GluPhe: 2.421 ± 0.012	3.703GluGly: 3.703 ± 0.017	1.201GluHis: 1.201 ± 0.009	3.734GluIle: 3.734 ± 0.016	4.435GluLys: 4.435 ± 0.025	6.082GluLeu: 6.082 ± 0.029	1.741GluMet: 1.741 ± 0.013	2.832GluAsn: 2.832 ± 0.015	1.984GluPro: 1.984 ± 0.013	2.098GluGln: 2.098 ± 0.016	3.165GluArg: 3.165 ± 0.018	4.365GluSer: 4.365 ± 0.025	2.964GluThr: 2.964 ± 0.016	4.179GluVal: 4.179 ± 0.021	0.79GluTrp: 0.79 ± 0.008	1.675GluTyr: 1.675 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	2.432PheAla: 2.432 ± 0.016	1.026PheCys: 1.026 ± 0.009	2.378PheAsp: 2.378 ± 0.012	2.298PheGlu: 2.298 ± 0.012	2.244PhePhe: 2.244 ± 0.017	3.267PheGly: 3.267 ± 0.02	1.151PheHis: 1.151 ± 0.009	2.236PheIle: 2.236 ± 0.015	2.232PheLys: 2.232 ± 0.013	4.687PheLeu: 4.687 ± 0.021	1.055PheMet: 1.055 ± 0.009	1.87PheAsn: 1.87 ± 0.013	2.166PhePro: 2.166 ± 0.014	1.66PheGln: 1.66 ± 0.011	2.129PheArg: 2.129 ± 0.014	4.3PheSer: 4.3 ± 0.02	2.133PheThr: 2.133 ± 0.014	2.887PheVal: 2.887 ± 0.013	0.683PheTrp: 0.683 ± 0.008	1.349PheTyr: 1.349 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	3.639GlyAla: 3.639 ± 0.018	1.455GlyCys: 1.455 ± 0.013	3.257GlyAsp: 3.257 ± 0.014	3.544GlyGlu: 3.544 ± 0.017	3.336GlyPhe: 3.336 ± 0.019	5.218GlyGly: 5.218 ± 0.038	1.484GlyHis: 1.484 ± 0.011	3.699GlyIle: 3.699 ± 0.016	3.99GlyLys: 3.99 ± 0.017	6.142GlyLeu: 6.142 ± 0.024	1.571GlyMet: 1.571 ± 0.012	3.178GlyAsn: 3.178 ± 0.018	2.367GlyPro: 2.367 ± 0.014	2.102GlyGln: 2.102 ± 0.013	3.508GlyArg: 3.508 ± 0.019	5.895GlySer: 5.895 ± 0.025	3.241GlyThr: 3.241 ± 0.016	4.248GlyVal: 4.248 ± 0.018	0.935GlyTrp: 0.935 ± 0.008	2.138GlyTyr: 2.138 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.326HisAla: 1.326 ± 0.01	0.58HisCys: 0.58 ± 0.006	1.169HisAsp: 1.169 ± 0.01	1.26HisGlu: 1.26 ± 0.011	1.148HisPhe: 1.148 ± 0.008	1.677HisGly: 1.677 ± 0.012	0.98HisHis: 0.98 ± 0.011	1.311HisIle: 1.311 ± 0.01	1.195HisLys: 1.195 ± 0.01	2.684HisLeu: 2.684 ± 0.017	0.589HisMet: 0.589 ± 0.006	1.016HisAsn: 1.016 ± 0.009	1.286HisPro: 1.286 ± 0.008	1.058HisGln: 1.058 ± 0.009	1.363HisArg: 1.363 ± 0.01	1.932HisSer: 1.932 ± 0.012	1.005HisThr: 1.005 ± 0.009	1.564HisVal: 1.564 ± 0.011	0.335HisTrp: 0.335 ± 0.005	0.741HisTyr: 0.741 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	3.515IleAla: 3.515 ± 0.018	1.228IleCys: 1.228 ± 0.01	2.875IleAsp: 2.875 ± 0.014	3.247IleGlu: 3.247 ± 0.017	2.431IlePhe: 2.431 ± 0.016	3.53IleGly: 3.53 ± 0.021	1.351IleHis: 1.351 ± 0.009	2.852IleIle: 2.852 ± 0.017	2.922IleLys: 2.922 ± 0.015	5.385IleLeu: 5.385 ± 0.022	1.238IleMet: 1.238 ± 0.009	2.206IleAsn: 2.206 ± 0.014	3.202IlePro: 3.202 ± 0.022	1.988IleGln: 1.988 ± 0.011	2.614IleArg: 2.614 ± 0.015	4.967IleSer: 4.967 ± 0.02	2.709IleThr: 2.709 ± 0.015	3.536IleVal: 3.536 ± 0.016	0.799IleTrp: 0.799 ± 0.009	1.626IleTyr: 1.626 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.943LysAla: 3.943 ± 0.019	1.039LysCys: 1.039 ± 0.01	3.091LysAsp: 3.091 ± 0.017	4.457LysGlu: 4.457 ± 0.023	2.24LysPhe: 2.24 ± 0.012	3.636LysGly: 3.636 ± 0.019	1.346LysHis: 1.346 ± 0.01	3.211LysIle: 3.211 ± 0.016	4.595LysLys: 4.595 ± 0.026	6.322LysLeu: 6.322 ± 0.029	1.575LysMet: 1.575 ± 0.011	2.658LysAsn: 2.658 ± 0.014	2.615LysPro: 2.615 ± 0.016	2.26LysGln: 2.26 ± 0.014	3.446LysArg: 3.446 ± 0.019	4.563LysSer: 4.563 ± 0.017	2.872LysThr: 2.872 ± 0.013	3.874LysVal: 3.874 ± 0.019	0.855LysTrp: 0.855 ± 0.008	1.685LysTyr: 1.685 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	6.389LeuAla: 6.389 ± 0.024	2.115LeuCys: 2.115 ± 0.014	5.369LeuAsp: 5.369 ± 0.023	6.53LeuGlu: 6.53 ± 0.032	4.174LeuPhe: 4.174 ± 0.02	6.085LeuGly: 6.085 ± 0.024	2.801LeuHis: 2.801 ± 0.014	4.954LeuIle: 4.954 ± 0.023	6.501LeuLys: 6.501 ± 0.025	10.428LeuLeu: 10.428 ± 0.035	2.242LeuMet: 2.242 ± 0.013	4.229LeuAsn: 4.229 ± 0.019	5.438LeuPro: 5.438 ± 0.024	4.447LeuGln: 4.447 ± 0.02	5.439LeuArg: 5.439 ± 0.024	9.295LeuSer: 9.295 ± 0.04	4.778LeuThr: 4.778 ± 0.023	6.804LeuVal: 6.804 ± 0.024	1.327LeuTrp: 1.327 ± 0.011	2.741LeuTyr: 2.741 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	2.078MetAla: 2.078 ± 0.013	0.378MetCys: 0.378 ± 0.004	1.396MetAsp: 1.396 ± 0.01	1.982MetGlu: 1.982 ± 0.013	0.898MetPhe: 0.898 ± 0.008	1.637MetGly: 1.637 ± 0.011	0.604MetHis: 0.604 ± 0.007	1.276MetIle: 1.276 ± 0.011	1.717MetLys: 1.717 ± 0.011	2.328MetLeu: 2.328 ± 0.013	0.712MetMet: 0.712 ± 0.008	1.053MetAsn: 1.053 ± 0.009	1.061MetPro: 1.061 ± 0.009	0.925MetGln: 0.925 ± 0.009	1.244MetArg: 1.244 ± 0.01	1.871MetSer: 1.871 ± 0.011	1.098MetThr: 1.098 ± 0.009	1.777MetVal: 1.777 ± 0.012	0.297MetTrp: 0.297 ± 0.004	0.62MetTyr: 0.62 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.536AsnAla: 2.536 ± 0.014	0.972AsnCys: 0.972 ± 0.009	1.997AsnAsp: 1.997 ± 0.013	2.403AsnGlu: 2.403 ± 0.014	2.103AsnPhe: 2.103 ± 0.013	3.122AsnGly: 3.122 ± 0.016	1.115AsnHis: 1.115 ± 0.009	2.458AsnIle: 2.458 ± 0.014	2.402AsnLys: 2.402 ± 0.014	5.202AsnLeu: 5.202 ± 0.029	1.188AsnMet: 1.188 ± 0.008	2.339AsnAsn: 2.339 ± 0.019	2.311AsnPro: 2.311 ± 0.014	1.771AsnGln: 1.771 ± 0.015	1.952AsnArg: 1.952 ± 0.012	3.865AsnSer: 3.865 ± 0.018	1.967AsnThr: 1.967 ± 0.012	2.836AsnVal: 2.836 ± 0.014	0.629AsnTrp: 0.629 ± 0.007	1.325AsnTyr: 1.325 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	2.813ProAla: 2.813 ± 0.018	0.809ProCys: 0.809 ± 0.008	2.38ProAsp: 2.38 ± 0.013	3.071ProGlu: 3.071 ± 0.017	1.966ProPhe: 1.966 ± 0.014	2.509ProGly: 2.509 ± 0.015	1.124ProHis: 1.124 ± 0.01	2.397ProIle: 2.397 ± 0.013	2.814ProLys: 2.814 ± 0.016	4.244ProLeu: 4.244 ± 0.02	0.983ProMet: 0.983 ± 0.008	2.426ProAsn: 2.426 ± 0.015	3.553ProPro: 3.553 ± 0.039	1.841ProGln: 1.841 ± 0.014	2.236ProArg: 2.236 ± 0.015	4.997ProSer: 4.997 ± 0.024	2.655ProThr: 2.655 ± 0.016	2.875ProVal: 2.875 ± 0.014	0.587ProTrp: 0.587 ± 0.007	1.313ProTyr: 1.313 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	2.288GlnAla: 2.288 ± 0.015	0.623GlnCys: 0.623 ± 0.006	1.614GlnAsp: 1.614 ± 0.012	2.308GlnGlu: 2.308 ± 0.015	1.491GlnPhe: 1.491 ± 0.011	2.158GlnGly: 2.158 ± 0.014	0.931GlnHis: 0.931 ± 0.008	2.101GlnIle: 2.101 ± 0.012	2.272GlnLys: 2.272 ± 0.013	3.893GlnLeu: 3.893 ± 0.023	0.957GlnMet: 0.957 ± 0.008	1.804GlnAsn: 1.804 ± 0.01	1.656GlnPro: 1.656 ± 0.012	1.947GlnGln: 1.947 ± 0.029	2.038GlnArg: 2.038 ± 0.014	2.825GlnSer: 2.825 ± 0.018	1.787GlnThr: 1.787 ± 0.011	2.446GlnVal: 2.446 ± 0.015	0.479GlnTrp: 0.479 ± 0.006	0.975GlnTyr: 0.975 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.009ArgAla: 3.009 ± 0.018	1.011ArgCys: 1.011 ± 0.009	2.557ArgAsp: 2.557 ± 0.014	3.137ArgGlu: 3.137 ± 0.018	2.254ArgPhe: 2.254 ± 0.014	3.133ArgGly: 3.133 ± 0.018	1.255ArgHis: 1.255 ± 0.01	2.866ArgIle: 2.866 ± 0.014	3.55ArgLys: 3.55 ± 0.02	5.144ArgLeu: 5.144 ± 0.021	1.315ArgMet: 1.315 ± 0.01	2.431ArgAsn: 2.431 ± 0.013	2.237ArgPro: 2.237 ± 0.014	1.736ArgGln: 1.736 ± 0.013	3.675ArgArg: 3.675 ± 0.02	4.226ArgSer: 4.226 ± 0.024	2.368ArgThr: 2.368 ± 0.013	3.31ArgVal: 3.31 ± 0.015	0.778ArgTrp: 0.778 ± 0.007	1.451ArgTyr: 1.451 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.041SerAla: 5.041 ± 0.021	1.84SerCys: 1.84 ± 0.013	4.244SerAsp: 4.244 ± 0.021	4.538SerGlu: 4.538 ± 0.024	4.201SerPhe: 4.201 ± 0.018	5.843SerGly: 5.843 ± 0.025	2.057SerHis: 2.057 ± 0.014	4.779SerIle: 4.779 ± 0.02	4.858SerLys: 4.858 ± 0.021	9.444SerLeu: 9.444 ± 0.035	2.125SerMet: 2.125 ± 0.014	4.124SerAsn: 4.124 ± 0.023	4.199SerPro: 4.199 ± 0.027	2.921SerGln: 2.921 ± 0.018	4.249SerArg: 4.249 ± 0.021	10.708SerSer: 10.708 ± 0.047	4.771SerThr: 4.771 ± 0.022	5.173SerVal: 5.173 ± 0.023	1.265SerTrp: 1.265 ± 0.011	2.442SerTyr: 2.442 ± 0.014	0.0SerXaa: 0.0 ± 0.0
Thr	3.29ThrAla: 3.29 ± 0.015	0.986ThrCys: 0.986 ± 0.009	2.269ThrAsp: 2.269 ± 0.014	2.691ThrGlu: 2.691 ± 0.014	2.133ThrPhe: 2.133 ± 0.014	3.212ThrGly: 3.212 ± 0.015	1.099ThrHis: 1.099 ± 0.01	2.814ThrIle: 2.814 ± 0.016	2.729ThrLys: 2.729 ± 0.015	4.92ThrLeu: 4.92 ± 0.022	1.248ThrMet: 1.248 ± 0.009	2.182ThrAsn: 2.182 ± 0.014	2.504ThrPro: 2.504 ± 0.017	1.612ThrGln: 1.612 ± 0.011	2.381ThrArg: 2.381 ± 0.015	4.656ThrSer: 4.656 ± 0.023	3.143ThrThr: 3.143 ± 0.02	3.292ThrVal: 3.292 ± 0.018	0.693ThrTrp: 0.693 ± 0.008	1.453ThrTyr: 1.453 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.675ValAla: 4.675 ± 0.021	1.278ValCys: 1.278 ± 0.009	3.608ValAsp: 3.608 ± 0.015	4.281ValGlu: 4.281 ± 0.019	2.896ValPhe: 2.896 ± 0.015	4.249ValGly: 4.249 ± 0.019	1.557ValHis: 1.557 ± 0.01	3.446ValIle: 3.446 ± 0.018	3.9ValLys: 3.9 ± 0.018	6.737ValLeu: 6.737 ± 0.024	1.575ValMet: 1.575 ± 0.01	2.56ValAsn: 2.56 ± 0.015	3.133ValPro: 3.133 ± 0.017	2.32ValGln: 2.32 ± 0.013	3.102ValArg: 3.102 ± 0.015	5.377ValSer: 5.377 ± 0.022	3.234ValThr: 3.234 ± 0.015	4.998ValVal: 4.998 ± 0.019	0.879ValTrp: 0.879 ± 0.008	2.038ValTyr: 2.038 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.796TrpAla: 0.796 ± 0.009	0.288TrpCys: 0.288 ± 0.004	0.691TrpAsp: 0.691 ± 0.008	0.79TrpGlu: 0.79 ± 0.007	0.658TrpPhe: 0.658 ± 0.007	0.804TrpGly: 0.804 ± 0.009	0.316TrpHis: 0.316 ± 0.005	0.774TrpIle: 0.774 ± 0.008	1.023TrpLys: 1.023 ± 0.009	1.379TrpLeu: 1.379 ± 0.011	0.386TrpMet: 0.386 ± 0.005	0.757TrpAsn: 0.757 ± 0.008	0.525TrpPro: 0.525 ± 0.006	0.444TrpGln: 0.444 ± 0.005	0.893TrpArg: 0.893 ± 0.009	1.072TrpSer: 1.072 ± 0.009	0.692TrpThr: 0.692 ± 0.008	0.932TrpVal: 0.932 ± 0.008	0.285TrpTrp: 0.285 ± 0.005	0.385TrpTyr: 0.385 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.777TyrAla: 1.777 ± 0.013	0.705TyrCys: 0.705 ± 0.007	1.544TyrAsp: 1.544 ± 0.011	1.558TyrGlu: 1.558 ± 0.011	1.386TyrPhe: 1.386 ± 0.011	2.183TyrGly: 2.183 ± 0.015	0.747TyrHis: 0.747 ± 0.007	1.568TyrIle: 1.568 ± 0.012	1.574TyrLys: 1.574 ± 0.01	3.073TyrLeu: 3.073 ± 0.016	0.832TyrMet: 0.832 ± 0.007	1.388TyrAsn: 1.388 ± 0.011	1.27TyrPro: 1.27 ± 0.01	0.949TyrGln: 0.949 ± 0.009	1.424TyrArg: 1.424 ± 0.011	2.349TyrSer: 2.349 ± 0.014	1.343TyrThr: 1.343 ± 0.011	1.823TyrVal: 1.823 ± 0.011	0.42TyrTrp: 0.42 ± 0.007	1.028TyrTyr: 1.028 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 45026 proteins (14462663 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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