Amino acid dipepetide frequency for Changjiang tombus-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.309AlaAla: 20.309 ± 6.491
0.967AlaCys: 0.967 ± 0.843
8.704AlaAsp: 8.704 ± 2.768
7.737AlaGlu: 7.737 ± 1.918
2.901AlaPhe: 2.901 ± 1.152
17.408AlaGly: 17.408 ± 5.469
3.868AlaHis: 3.868 ± 1.828
0.967AlaIle: 0.967 ± 0.655
0.967AlaLys: 0.967 ± 0.655
10.638AlaLeu: 10.638 ± 3.845
1.934AlaMet: 1.934 ± 1.686
5.803AlaAsn: 5.803 ± 2.729
3.868AlaPro: 3.868 ± 1.271
5.803AlaGln: 5.803 ± 1.211
11.605AlaArg: 11.605 ± 4.092
7.737AlaSer: 7.737 ± 2.357
2.901AlaThr: 2.901 ± 1.765
5.803AlaVal: 5.803 ± 0.417
2.901AlaTrp: 2.901 ± 0.587
4.836AlaTyr: 4.836 ± 1.285
0.0AlaXaa: 0.0 ± 0.0
Cys
1.934CysAla: 1.934 ± 0.914
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.967CysGlu: 0.967 ± 0.655
0.967CysPhe: 0.967 ± 0.655
2.901CysGly: 2.901 ± 0.587
0.967CysHis: 0.967 ± 1.097
0.967CysIle: 0.967 ± 0.655
0.0CysLys: 0.0 ± 0.0
2.901CysLeu: 2.901 ± 0.587
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.967CysPro: 0.967 ± 1.097
1.934CysGln: 1.934 ± 1.311
0.967CysArg: 0.967 ± 0.655
0.967CysSer: 0.967 ± 0.655
3.868CysThr: 3.868 ± 2.622
1.934CysVal: 1.934 ± 0.636
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.77AspAla: 6.77 ± 0.679
1.934AspCys: 1.934 ± 1.311
0.967AspAsp: 0.967 ± 0.655
1.934AspGlu: 1.934 ± 0.914
0.967AspPhe: 0.967 ± 0.655
2.901AspGly: 2.901 ± 0.978
0.0AspHis: 0.0 ± 0.0
1.934AspIle: 1.934 ± 2.194
0.967AspLys: 0.967 ± 1.097
0.0AspLeu: 0.0 ± 0.0
1.934AspMet: 1.934 ± 1.311
1.934AspAsn: 1.934 ± 1.686
5.803AspPro: 5.803 ± 1.957
1.934AspGln: 1.934 ± 0.636
2.901AspArg: 2.901 ± 1.91
0.967AspSer: 0.967 ± 1.097
1.934AspThr: 1.934 ± 1.204
1.934AspVal: 1.934 ± 1.311
0.0AspTrp: 0.0 ± 0.0
0.967AspTyr: 0.967 ± 0.655
0.0AspXaa: 0.0 ± 0.0
Glu
2.901GluAla: 2.901 ± 2.143
1.934GluCys: 1.934 ± 0.914
0.967GluAsp: 0.967 ± 1.097
3.868GluGlu: 3.868 ± 0.317
3.868GluPhe: 3.868 ± 1.539
3.868GluGly: 3.868 ± 1.641
2.901GluHis: 2.901 ± 1.966
1.934GluIle: 1.934 ± 0.914
0.967GluLys: 0.967 ± 0.655
2.901GluLeu: 2.901 ± 2.143
2.901GluMet: 2.901 ± 1.152
1.934GluAsn: 1.934 ± 1.686
0.0GluPro: 0.0 ± 0.0
0.967GluGln: 0.967 ± 0.655
4.836GluArg: 4.836 ± 3.277
5.803GluSer: 5.803 ± 1.957
0.0GluThr: 0.0 ± 0.0
5.803GluVal: 5.803 ± 2.742
1.934GluTrp: 1.934 ± 0.636
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.967PheAla: 0.967 ± 1.097
1.934PheCys: 1.934 ± 1.311
1.934PheAsp: 1.934 ± 1.311
2.901PheGlu: 2.901 ± 0.978
1.934PhePhe: 1.934 ± 1.311
7.737PheGly: 7.737 ± 0.936
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.934PheLys: 1.934 ± 1.311
2.901PheLeu: 2.901 ± 1.341
0.0PheMet: 0.0 ± 0.56
2.901PheAsn: 2.901 ± 0.978
1.934PhePro: 1.934 ± 0.914
0.0PheGln: 0.0 ± 0.0
2.901PheArg: 2.901 ± 1.341
2.901PheSer: 2.901 ± 0.978
1.934PheThr: 1.934 ± 0.636
3.868PheVal: 3.868 ± 1.271
0.967PheTrp: 0.967 ± 1.097
0.967PheTyr: 0.967 ± 0.655
0.0PheXaa: 0.0 ± 0.0
Gly
12.573GlyAla: 12.573 ± 3.837
1.934GlyCys: 1.934 ± 0.914
1.934GlyAsp: 1.934 ± 1.311
3.868GlyGlu: 3.868 ± 1.636
5.803GlyPhe: 5.803 ± 0.417
6.77GlyGly: 6.77 ± 1.027
0.967GlyHis: 0.967 ± 0.655
5.803GlyIle: 5.803 ± 1.907
1.934GlyLys: 1.934 ± 0.914
11.605GlyLeu: 11.605 ± 2.29
1.934GlyMet: 1.934 ± 0.636
2.901GlyAsn: 2.901 ± 1.341
2.901GlyPro: 2.901 ± 1.341
3.868GlyGln: 3.868 ± 1.271
4.836GlyArg: 4.836 ± 0.544
3.868GlySer: 3.868 ± 1.129
6.77GlyThr: 6.77 ± 1.591
8.704GlyVal: 8.704 ± 1.385
0.967GlyTrp: 0.967 ± 0.655
3.868GlyTyr: 3.868 ± 2.148
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.967HisCys: 0.967 ± 1.097
0.967HisAsp: 0.967 ± 0.655
0.0HisGlu: 0.0 ± 0.0
2.901HisPhe: 2.901 ± 1.765
3.868HisGly: 3.868 ± 2.622
0.0HisHis: 0.0 ± 0.0
0.967HisIle: 0.967 ± 0.655
0.967HisLys: 0.967 ± 0.655
0.967HisLeu: 0.967 ± 0.655
1.934HisMet: 1.934 ± 1.311
0.967HisAsn: 0.967 ± 0.655
3.868HisPro: 3.868 ± 0.317
0.0HisGln: 0.0 ± 0.0
1.934HisArg: 1.934 ± 1.311
0.967HisSer: 0.967 ± 0.655
0.0HisThr: 0.0 ± 0.0
0.967HisVal: 0.967 ± 0.655
0.0HisTrp: 0.0 ± 0.0
1.934HisTyr: 1.934 ± 1.204
0.0HisXaa: 0.0 ± 0.0
Ile
1.934IleAla: 1.934 ± 0.914
0.967IleCys: 0.967 ± 0.655
0.967IleAsp: 0.967 ± 1.097
2.901IleGlu: 2.901 ± 1.152
0.967IlePhe: 0.967 ± 1.097
1.934IleGly: 1.934 ± 1.686
0.967IleHis: 0.967 ± 0.655
0.967IleIle: 0.967 ± 0.843
1.934IleLys: 1.934 ± 1.311
0.967IleLeu: 0.967 ± 1.097
2.901IleMet: 2.901 ± 0.978
2.901IleAsn: 2.901 ± 0.978
0.967IlePro: 0.967 ± 0.655
2.901IleGln: 2.901 ± 1.341
3.868IleArg: 3.868 ± 0.317
4.836IleSer: 4.836 ± 0.544
2.901IleThr: 2.901 ± 2.143
1.934IleVal: 1.934 ± 2.194
0.0IleTrp: 0.0 ± 0.0
0.967IleTyr: 0.967 ± 0.655
0.0IleXaa: 0.0 ± 0.0
Lys
5.803LysAla: 5.803 ± 2.303
0.967LysCys: 0.967 ± 0.655
0.967LysAsp: 0.967 ± 0.655
0.967LysGlu: 0.967 ± 1.097
0.0LysPhe: 0.0 ± 0.0
2.901LysGly: 2.901 ± 1.966
1.934LysHis: 1.934 ± 1.311
3.868LysIle: 3.868 ± 0.317
0.0LysLys: 0.0 ± 0.0
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
0.967LysAsn: 0.967 ± 0.655
3.868LysPro: 3.868 ± 1.129
0.967LysGln: 0.967 ± 0.655
2.901LysArg: 2.901 ± 1.765
1.934LysSer: 1.934 ± 1.686
0.967LysThr: 0.967 ± 1.097
2.901LysVal: 2.901 ± 0.587
1.934LysTrp: 1.934 ± 0.914
0.967LysTyr: 0.967 ± 0.655
0.0LysXaa: 0.0 ± 0.0
Leu
10.638LeuAla: 10.638 ± 1.778
0.0LeuCys: 0.0 ± 0.0
3.868LeuAsp: 3.868 ± 1.271
0.967LeuGlu: 0.967 ± 1.097
0.967LeuPhe: 0.967 ± 0.843
3.868LeuGly: 3.868 ± 1.828
1.934LeuHis: 1.934 ± 0.914
7.737LeuIle: 7.737 ± 0.936
2.901LeuLys: 2.901 ± 0.978
6.77LeuLeu: 6.77 ± 2.207
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
6.77LeuPro: 6.77 ± 0.679
1.934LeuGln: 1.934 ± 1.311
4.836LeuArg: 4.836 ± 2.729
5.803LeuSer: 5.803 ± 1.479
8.704LeuThr: 8.704 ± 3.016
5.803LeuVal: 5.803 ± 0.417
0.0LeuTrp: 0.0 ± 0.0
0.967LeuTyr: 0.967 ± 0.655
0.0LeuXaa: 0.0 ± 0.0
Met
4.836MetAla: 4.836 ± 1.923
0.967MetCys: 0.967 ± 0.655
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.967MetPhe: 0.967 ± 0.655
0.0MetGly: 0.0 ± 0.0
1.934MetHis: 1.934 ± 1.311
0.0MetIle: 0.0 ± 0.0
2.901MetLys: 2.901 ± 1.152
2.901MetLeu: 2.901 ± 1.966
0.967MetMet: 0.967 ± 0.67
0.967MetAsn: 0.967 ± 0.655
0.0MetPro: 0.0 ± 0.0
0.967MetGln: 0.967 ± 1.097
1.934MetArg: 1.934 ± 0.914
2.901MetSer: 2.901 ± 1.341
0.967MetThr: 0.967 ± 0.843
0.967MetVal: 0.967 ± 0.655
0.967MetTrp: 0.967 ± 0.655
0.967MetTyr: 0.967 ± 0.655
0.0MetXaa: 0.0 ± 0.0
Asn
7.737AsnAla: 7.737 ± 1.832
0.967AsnCys: 0.967 ± 0.655
1.934AsnAsp: 1.934 ± 0.636
0.967AsnGlu: 0.967 ± 0.655
3.868AsnPhe: 3.868 ± 2.148
1.934AsnGly: 1.934 ± 1.311
0.967AsnHis: 0.967 ± 0.843
1.934AsnIle: 1.934 ± 2.194
2.901AsnLys: 2.901 ± 1.341
0.0AsnLeu: 0.0 ± 0.0
2.901AsnMet: 2.901 ± 0.978
3.868AsnAsn: 3.868 ± 1.271
0.967AsnPro: 0.967 ± 0.843
0.0AsnGln: 0.0 ± 0.0
0.967AsnArg: 0.967 ± 0.843
0.967AsnSer: 0.967 ± 0.655
3.868AsnThr: 3.868 ± 1.271
2.901AsnVal: 2.901 ± 1.341
0.967AsnTrp: 0.967 ± 1.097
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.836ProAla: 4.836 ± 0.544
2.901ProCys: 2.901 ± 0.587
2.901ProAsp: 2.901 ± 1.966
1.934ProGlu: 1.934 ± 0.914
0.967ProPhe: 0.967 ± 0.655
7.737ProGly: 7.737 ± 3.067
0.967ProHis: 0.967 ± 0.843
0.0ProIle: 0.0 ± 0.0
2.901ProLys: 2.901 ± 1.765
3.868ProLeu: 3.868 ± 0.317
1.934ProMet: 1.934 ± 0.636
1.934ProAsn: 1.934 ± 1.686
5.803ProPro: 5.803 ± 3.819
0.0ProGln: 0.0 ± 0.0
5.803ProArg: 5.803 ± 2.787
4.836ProSer: 4.836 ± 0.544
3.868ProThr: 3.868 ± 1.539
3.868ProVal: 3.868 ± 1.539
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.901GlnAla: 2.901 ± 1.152
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.836GlnGlu: 4.836 ± 0.846
0.967GlnPhe: 0.967 ± 0.655
1.934GlnGly: 1.934 ± 1.686
0.967GlnHis: 0.967 ± 0.655
1.934GlnIle: 1.934 ± 1.311
0.0GlnLys: 0.0 ± 0.0
2.901GlnLeu: 2.901 ± 0.978
0.967GlnMet: 0.967 ± 1.097
0.967GlnAsn: 0.967 ± 0.843
1.934GlnPro: 1.934 ± 0.636
0.0GlnGln: 0.0 ± 0.0
0.967GlnArg: 0.967 ± 0.655
0.0GlnSer: 0.0 ± 0.0
0.967GlnThr: 0.967 ± 0.843
0.967GlnVal: 0.967 ± 0.843
1.934GlnTrp: 1.934 ± 0.914
0.967GlnTyr: 0.967 ± 1.097
0.0GlnXaa: 0.0 ± 0.0
Arg
8.704ArgAla: 8.704 ± 4.024
2.901ArgCys: 2.901 ± 0.978
8.704ArgAsp: 8.704 ± 1.516
2.901ArgGlu: 2.901 ± 1.152
0.967ArgPhe: 0.967 ± 0.655
1.934ArgGly: 1.934 ± 1.686
0.967ArgHis: 0.967 ± 0.655
0.967ArgIle: 0.967 ± 0.843
4.836ArgLys: 4.836 ± 1.285
9.671ArgLeu: 9.671 ± 0.381
0.967ArgMet: 0.967 ± 0.655
3.868ArgAsn: 3.868 ± 1.129
3.868ArgPro: 3.868 ± 2.622
1.934ArgGln: 1.934 ± 1.204
6.77ArgArg: 6.77 ± 2.151
3.868ArgSer: 3.868 ± 1.641
3.868ArgThr: 3.868 ± 0.317
7.737ArgVal: 7.737 ± 1.918
0.0ArgTrp: 0.0 ± 0.0
0.967ArgTyr: 0.967 ± 0.655
0.0ArgXaa: 0.0 ± 0.0
Ser
7.737SerAla: 7.737 ± 3.617
0.967SerCys: 0.967 ± 0.655
0.967SerAsp: 0.967 ± 0.655
3.868SerGlu: 3.868 ± 2.49
4.836SerPhe: 4.836 ± 0.846
10.638SerGly: 10.638 ± 3.339
0.0SerHis: 0.0 ± 0.0
3.868SerIle: 3.868 ± 0.317
2.901SerLys: 2.901 ± 0.978
3.868SerLeu: 3.868 ± 1.828
0.0SerMet: 0.0 ± 0.0
0.967SerAsn: 0.967 ± 0.843
5.803SerPro: 5.803 ± 1.957
0.0SerGln: 0.0 ± 0.0
5.803SerArg: 5.803 ± 1.211
1.934SerSer: 1.934 ± 0.914
1.934SerThr: 1.934 ± 0.914
3.868SerVal: 3.868 ± 1.129
1.934SerTrp: 1.934 ± 0.636
0.967SerTyr: 0.967 ± 0.843
0.0SerXaa: 0.0 ± 0.0
Thr
11.605ThrAla: 11.605 ± 3.902
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
1.934ThrGlu: 1.934 ± 1.686
3.868ThrPhe: 3.868 ± 1.271
4.836ThrGly: 4.836 ± 0.846
0.0ThrHis: 0.0 ± 0.0
0.967ThrIle: 0.967 ± 1.097
3.868ThrLys: 3.868 ± 2.977
1.934ThrLeu: 1.934 ± 0.636
0.967ThrMet: 0.967 ± 0.655
2.901ThrAsn: 2.901 ± 0.978
2.901ThrPro: 2.901 ± 1.341
0.0ThrGln: 0.0 ± 0.0
3.868ThrArg: 3.868 ± 2.148
4.836ThrSer: 4.836 ± 3.273
1.934ThrThr: 1.934 ± 0.914
4.836ThrVal: 4.836 ± 0.846
0.0ThrTrp: 0.0 ± 0.0
2.901ThrTyr: 2.901 ± 0.587
0.0ThrXaa: 0.0 ± 0.0
Val
9.671ValAla: 9.671 ± 2.443
1.934ValCys: 1.934 ± 0.914
0.967ValAsp: 0.967 ± 0.655
4.836ValGlu: 4.836 ± 1.973
1.934ValPhe: 1.934 ± 1.311
6.77ValGly: 6.77 ± 2.106
2.901ValHis: 2.901 ± 1.341
1.934ValIle: 1.934 ± 0.636
0.967ValLys: 0.967 ± 0.655
0.967ValLeu: 0.967 ± 0.843
1.934ValMet: 1.934 ± 0.777
1.934ValAsn: 1.934 ± 0.636
3.868ValPro: 3.868 ± 1.129
0.967ValGln: 0.967 ± 1.097
8.704ValArg: 8.704 ± 2.464
5.803ValSer: 5.803 ± 2.787
3.868ValThr: 3.868 ± 1.641
1.934ValVal: 1.934 ± 1.311
1.934ValTrp: 1.934 ± 1.204
3.868ValTyr: 3.868 ± 1.539
0.0ValXaa: 0.0 ± 0.0
Trp
2.901TrpAla: 2.901 ± 2.143
0.0TrpCys: 0.0 ± 0.0
0.967TrpAsp: 0.967 ± 1.097
0.967TrpGlu: 0.967 ± 0.655
0.967TrpPhe: 0.967 ± 0.655
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.934TrpIle: 1.934 ± 0.914
0.967TrpLys: 0.967 ± 0.843
3.868TrpLeu: 3.868 ± 1.828
0.0TrpMet: 0.0 ± 0.0
0.967TrpAsn: 0.967 ± 0.655
0.0TrpPro: 0.0 ± 0.0
1.934TrpGln: 1.934 ± 0.636
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.967TrpVal: 0.967 ± 0.843
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.901TyrAla: 2.901 ± 0.587
0.0TyrCys: 0.0 ± 0.0
0.967TyrAsp: 0.967 ± 1.097
1.934TyrGlu: 1.934 ± 0.636
0.967TyrPhe: 0.967 ± 0.843
3.868TyrGly: 3.868 ± 1.828
1.934TyrHis: 1.934 ± 1.311
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
4.836TyrLeu: 4.836 ± 0.846
0.967TyrMet: 0.967 ± 0.655
1.934TyrAsn: 1.934 ± 1.311
0.967TyrPro: 0.967 ± 0.843
0.0TyrGln: 0.0 ± 0.0
0.0TyrArg: 0.0 ± 0.0
1.934TyrSer: 1.934 ± 0.636
2.901TyrThr: 2.901 ± 1.341
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.967TyrTyr: 0.967 ± 0.655
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1035 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski