Amino acid dipepetide frequency for Qingshengfaniella alkalisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.658AlaAla: 13.658 ± 0.137	1.004AlaCys: 1.004 ± 0.031	6.872AlaAsp: 6.872 ± 0.107	7.341AlaGlu: 7.341 ± 0.098	4.05AlaPhe: 4.05 ± 0.066	9.357AlaGly: 9.357 ± 0.096	2.052AlaHis: 2.052 ± 0.045	6.102AlaIle: 6.102 ± 0.08	3.692AlaLys: 3.692 ± 0.067	12.375AlaLeu: 12.375 ± 0.126	3.546AlaMet: 3.546 ± 0.056	2.86AlaAsn: 2.86 ± 0.06	4.896AlaPro: 4.896 ± 0.079	4.283AlaGln: 4.283 ± 0.065	7.576AlaArg: 7.576 ± 0.106	5.79AlaSer: 5.79 ± 0.066	5.914AlaThr: 5.914 ± 0.078	8.065AlaVal: 8.065 ± 0.09	1.318AlaTrp: 1.318 ± 0.04	2.465AlaTyr: 2.465 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.991CysAla: 0.991 ± 0.029	0.117CysCys: 0.117 ± 0.01	0.601CysAsp: 0.601 ± 0.024	0.475CysGlu: 0.475 ± 0.023	0.332CysPhe: 0.332 ± 0.016	0.918CysGly: 0.918 ± 0.031	0.264CysHis: 0.264 ± 0.019	0.414CysIle: 0.414 ± 0.019	0.206CysLys: 0.206 ± 0.014	0.93CysLeu: 0.93 ± 0.029	0.161CysMet: 0.161 ± 0.011	0.227CysAsn: 0.227 ± 0.016	0.498CysPro: 0.498 ± 0.024	0.235CysGln: 0.235 ± 0.015	0.549CysArg: 0.549 ± 0.024	0.518CysSer: 0.518 ± 0.022	0.414CysThr: 0.414 ± 0.021	0.675CysVal: 0.675 ± 0.022	0.114CysTrp: 0.114 ± 0.009	0.195CysTyr: 0.195 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.365AspAla: 7.365 ± 0.095	0.523AspCys: 0.523 ± 0.023	3.985AspAsp: 3.985 ± 0.093	3.937AspGlu: 3.937 ± 0.07	2.446AspPhe: 2.446 ± 0.049	5.985AspGly: 5.985 ± 0.14	1.413AspHis: 1.413 ± 0.032	3.468AspIle: 3.468 ± 0.064	1.76AspLys: 1.76 ± 0.045	6.513AspLeu: 6.513 ± 0.084	1.692AspMet: 1.692 ± 0.039	1.548AspAsn: 1.548 ± 0.041	3.939AspPro: 3.939 ± 0.087	2.059AspGln: 2.059 ± 0.049	4.433AspArg: 4.433 ± 0.068	2.59AspSer: 2.59 ± 0.06	3.281AspThr: 3.281 ± 0.087	4.582AspVal: 4.582 ± 0.07	1.179AspTrp: 1.179 ± 0.035	1.62AspTyr: 1.62 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	7.134GluAla: 7.134 ± 0.094	0.389GluCys: 0.389 ± 0.02	3.511GluAsp: 3.511 ± 0.064	3.397GluGlu: 3.397 ± 0.064	1.954GluPhe: 1.954 ± 0.045	4.617GluGly: 4.617 ± 0.074	1.229GluHis: 1.229 ± 0.033	3.883GluIle: 3.883 ± 0.054	2.164GluLys: 2.164 ± 0.047	5.679GluLeu: 5.679 ± 0.069	1.76GluMet: 1.76 ± 0.036	1.936GluAsn: 1.936 ± 0.04	2.601GluPro: 2.601 ± 0.055	2.254GluGln: 2.254 ± 0.046	4.395GluArg: 4.395 ± 0.062	2.49GluSer: 2.49 ± 0.05	3.724GluThr: 3.724 ± 0.062	4.117GluVal: 4.117 ± 0.067	0.759GluTrp: 0.759 ± 0.027	1.113GluTyr: 1.113 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.189PheAla: 4.189 ± 0.068	0.403PheCys: 0.403 ± 0.019	2.967PheAsp: 2.967 ± 0.052	2.236PheGlu: 2.236 ± 0.048	1.433PhePhe: 1.433 ± 0.047	3.648PheGly: 3.648 ± 0.068	0.742PheHis: 0.742 ± 0.025	1.881PheIle: 1.881 ± 0.047	0.935PheLys: 0.935 ± 0.031	3.511PheLeu: 3.511 ± 0.077	0.889PheMet: 0.889 ± 0.031	1.142PheAsn: 1.142 ± 0.036	1.579PhePro: 1.579 ± 0.038	1.087PheGln: 1.087 ± 0.038	2.166PheArg: 2.166 ± 0.046	2.372PheSer: 2.372 ± 0.044	2.13PheThr: 2.13 ± 0.059	2.808PheVal: 2.808 ± 0.052	0.555PheTrp: 0.555 ± 0.024	0.938PheTyr: 0.938 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	8.756GlyAla: 8.756 ± 0.088	0.864GlyCys: 0.864 ± 0.03	4.855GlyAsp: 4.855 ± 0.085	4.668GlyGlu: 4.668 ± 0.068	3.579GlyPhe: 3.579 ± 0.058	7.05GlyGly: 7.05 ± 0.112	1.832GlyHis: 1.832 ± 0.04	4.712GlyIle: 4.712 ± 0.081	3.153GlyLys: 3.153 ± 0.058	8.916GlyLeu: 8.916 ± 0.109	2.498GlyMet: 2.498 ± 0.052	2.252GlyAsn: 2.252 ± 0.053	3.408GlyPro: 3.408 ± 0.052	3.106GlyGln: 3.106 ± 0.057	5.472GlyArg: 5.472 ± 0.083	4.579GlySer: 4.579 ± 0.077	4.771GlyThr: 4.771 ± 0.099	6.378GlyVal: 6.378 ± 0.073	1.41GlyTrp: 1.41 ± 0.036	2.264GlyTyr: 2.264 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.193HisAla: 2.193 ± 0.044	0.253HisCys: 0.253 ± 0.015	1.336HisAsp: 1.336 ± 0.035	1.046HisGlu: 1.046 ± 0.034	0.808HisPhe: 0.808 ± 0.027	1.819HisGly: 1.819 ± 0.044	0.546HisHis: 0.546 ± 0.026	1.064HisIle: 1.064 ± 0.033	0.537HisLys: 0.537 ± 0.022	2.113HisLeu: 2.113 ± 0.05	0.518HisMet: 0.518 ± 0.021	0.482HisAsn: 0.482 ± 0.021	1.33HisPro: 1.33 ± 0.03	0.61HisGln: 0.61 ± 0.023	1.341HisArg: 1.341 ± 0.038	1.016HisSer: 1.016 ± 0.032	0.835HisThr: 0.835 ± 0.027	1.47HisVal: 1.47 ± 0.037	0.319HisTrp: 0.319 ± 0.016	0.528HisTyr: 0.528 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.18IleAla: 7.18 ± 0.088	0.619IleCys: 0.619 ± 0.025	3.846IleAsp: 3.846 ± 0.062	3.802IleGlu: 3.802 ± 0.058	1.934IlePhe: 1.934 ± 0.047	5.1IleGly: 5.1 ± 0.082	1.012IleHis: 1.012 ± 0.032	2.61IleIle: 2.61 ± 0.058	1.396IleLys: 1.396 ± 0.04	4.87IleLeu: 4.87 ± 0.082	1.162IleMet: 1.162 ± 0.037	1.489IleAsn: 1.489 ± 0.037	2.558IlePro: 2.558 ± 0.05	1.252IleGln: 1.252 ± 0.03	3.467IleArg: 3.467 ± 0.052	3.318IleSer: 3.318 ± 0.054	3.004IleThr: 3.004 ± 0.064	4.191IleVal: 4.191 ± 0.072	0.735IleTrp: 0.735 ± 0.026	1.273IleTyr: 1.273 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.661LysAla: 3.661 ± 0.061	0.206LysCys: 0.206 ± 0.013	1.841LysAsp: 1.841 ± 0.048	1.622LysGlu: 1.622 ± 0.045	0.953LysPhe: 0.953 ± 0.031	2.59LysGly: 2.59 ± 0.048	0.657LysHis: 0.657 ± 0.026	1.7LysIle: 1.7 ± 0.042	1.181LysLys: 1.181 ± 0.041	3.267LysLeu: 3.267 ± 0.065	0.856LysMet: 0.856 ± 0.027	0.898LysAsn: 0.898 ± 0.029	1.832LysPro: 1.832 ± 0.045	1.001LysGln: 1.001 ± 0.031	2.291LysArg: 2.291 ± 0.048	1.94LysSer: 1.94 ± 0.044	1.921LysThr: 1.921 ± 0.047	2.363LysVal: 2.363 ± 0.051	0.398LysTrp: 0.398 ± 0.017	0.631LysTyr: 0.631 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	11.895LeuAla: 11.895 ± 0.135	0.986LeuCys: 0.986 ± 0.028	6.629LeuAsp: 6.629 ± 0.08	5.352LeuGlu: 5.352 ± 0.066	3.587LeuPhe: 3.587 ± 0.078	8.201LeuGly: 8.201 ± 0.099	1.899LeuHis: 1.899 ± 0.045	5.478LeuIle: 5.478 ± 0.087	3.262LeuLys: 3.262 ± 0.056	9.153LeuLeu: 9.153 ± 0.137	2.48LeuMet: 2.48 ± 0.055	2.922LeuAsn: 2.922 ± 0.056	5.375LeuPro: 5.375 ± 0.07	2.955LeuGln: 2.955 ± 0.049	6.772LeuArg: 6.772 ± 0.093	7.021LeuSer: 7.021 ± 0.071	6.06LeuThr: 6.06 ± 0.084	6.925LeuVal: 6.925 ± 0.093	1.18LeuTrp: 1.18 ± 0.034	1.999LeuTyr: 1.999 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	3.053MetAla: 3.053 ± 0.055	0.178MetCys: 0.178 ± 0.011	1.427MetAsp: 1.427 ± 0.032	1.276MetGlu: 1.276 ± 0.034	0.853MetPhe: 0.853 ± 0.029	2.086MetGly: 2.086 ± 0.043	0.454MetHis: 0.454 ± 0.021	1.616MetIle: 1.616 ± 0.044	1.041MetLys: 1.041 ± 0.03	2.669MetLeu: 2.669 ± 0.058	0.727MetMet: 0.727 ± 0.029	0.923MetAsn: 0.923 ± 0.029	1.417MetPro: 1.417 ± 0.037	0.948MetGln: 0.948 ± 0.031	1.975MetArg: 1.975 ± 0.046	1.819MetSer: 1.819 ± 0.038	2.081MetThr: 2.081 ± 0.043	1.846MetVal: 1.846 ± 0.044	0.26MetTrp: 0.26 ± 0.016	0.327MetTyr: 0.327 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.207AsnAla: 3.207 ± 0.06	0.276AsnCys: 0.276 ± 0.019	1.775AsnAsp: 1.775 ± 0.069	1.489AsnGlu: 1.489 ± 0.04	1.05AsnPhe: 1.05 ± 0.031	2.607AsnGly: 2.607 ± 0.072	0.604AsnHis: 0.604 ± 0.026	1.489AsnIle: 1.489 ± 0.039	0.741AsnLys: 0.741 ± 0.026	2.648AsnLeu: 2.648 ± 0.051	0.704AsnMet: 0.704 ± 0.025	0.751AsnAsn: 0.751 ± 0.028	1.962AsnPro: 1.962 ± 0.042	0.803AsnGln: 0.803 ± 0.025	1.84AsnArg: 1.84 ± 0.041	1.364AsnSer: 1.364 ± 0.039	1.44AsnThr: 1.44 ± 0.039	2.054AsnVal: 2.054 ± 0.041	0.466AsnTrp: 0.466 ± 0.021	0.728AsnTyr: 0.728 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.095ProAla: 5.095 ± 0.071	0.352ProCys: 0.352 ± 0.018	4.275ProAsp: 4.275 ± 0.092	4.069ProGlu: 4.069 ± 0.066	1.956ProPhe: 1.956 ± 0.037	3.905ProGly: 3.905 ± 0.066	1.006ProHis: 1.006 ± 0.032	2.323ProIle: 2.323 ± 0.044	1.633ProLys: 1.633 ± 0.044	4.46ProLeu: 4.46 ± 0.062	1.224ProMet: 1.224 ± 0.032	1.426ProAsn: 1.426 ± 0.035	2.137ProPro: 2.137 ± 0.063	1.677ProGln: 1.677 ± 0.042	2.677ProArg: 2.677 ± 0.048	2.772ProSer: 2.772 ± 0.053	2.602ProThr: 2.602 ± 0.053	4.272ProVal: 4.272 ± 0.066	0.649ProTrp: 0.649 ± 0.026	1.166ProTyr: 1.166 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.781GlnAla: 3.781 ± 0.058	0.213GlnCys: 0.213 ± 0.013	1.873GlnAsp: 1.873 ± 0.039	1.604GlnGlu: 1.604 ± 0.042	1.148GlnPhe: 1.148 ± 0.031	2.542GlnGly: 2.542 ± 0.057	0.593GlnHis: 0.593 ± 0.023	2.246GlnIle: 2.246 ± 0.045	1.126GlnLys: 1.126 ± 0.033	3.017GlnLeu: 3.017 ± 0.053	1.138GlnMet: 1.138 ± 0.033	0.972GlnAsn: 0.972 ± 0.03	1.686GlnPro: 1.686 ± 0.037	1.274GlnGln: 1.274 ± 0.042	2.253GlnArg: 2.253 ± 0.046	2.139GlnSer: 2.139 ± 0.047	1.857GlnThr: 1.857 ± 0.037	2.402GlnVal: 2.402 ± 0.052	0.403GlnTrp: 0.403 ± 0.018	0.64GlnTyr: 0.64 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	6.916ArgAla: 6.916 ± 0.093	0.514ArgCys: 0.514 ± 0.02	4.401ArgAsp: 4.401 ± 0.063	3.908ArgGlu: 3.908 ± 0.064	2.613ArgPhe: 2.613 ± 0.051	4.34ArgGly: 4.34 ± 0.073	1.541ArgHis: 1.541 ± 0.037	3.883ArgIle: 3.883 ± 0.062	2.537ArgLys: 2.537 ± 0.054	7.074ArgLeu: 7.074 ± 0.106	1.912ArgMet: 1.912 ± 0.044	1.976ArgAsn: 1.976 ± 0.044	2.94ArgPro: 2.94 ± 0.048	2.41ArgGln: 2.41 ± 0.047	4.754ArgArg: 4.754 ± 0.094	3.656ArgSer: 3.656 ± 0.055	3.089ArgThr: 3.089 ± 0.046	4.722ArgVal: 4.722 ± 0.081	0.893ArgTrp: 0.893 ± 0.028	1.657ArgTyr: 1.657 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.975SerAla: 5.975 ± 0.071	0.454SerCys: 0.454 ± 0.021	3.833SerAsp: 3.833 ± 0.073	3.259SerGlu: 3.259 ± 0.057	2.429SerPhe: 2.429 ± 0.048	5.863SerGly: 5.863 ± 0.082	1.122SerHis: 1.122 ± 0.036	2.91SerIle: 2.91 ± 0.054	1.639SerLys: 1.639 ± 0.038	5.466SerLeu: 5.466 ± 0.073	1.451SerMet: 1.451 ± 0.041	1.517SerAsn: 1.517 ± 0.035	2.616SerPro: 2.616 ± 0.05	1.762SerGln: 1.762 ± 0.043	3.545SerArg: 3.545 ± 0.063	2.915SerSer: 2.915 ± 0.06	2.86SerThr: 2.86 ± 0.051	4.265SerVal: 4.265 ± 0.071	0.765SerTrp: 0.765 ± 0.031	1.474SerTyr: 1.474 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	5.986ThrAla: 5.986 ± 0.083	0.475ThrCys: 0.475 ± 0.024	3.565ThrAsp: 3.565 ± 0.103	3.053ThrGlu: 3.053 ± 0.053	2.026ThrPhe: 2.026 ± 0.049	5.232ThrGly: 5.232 ± 0.092	1.121ThrHis: 1.121 ± 0.034	2.99ThrIle: 2.99 ± 0.062	1.589ThrLys: 1.589 ± 0.038	6.047ThrLeu: 6.047 ± 0.097	1.273ThrMet: 1.273 ± 0.031	1.46ThrAsn: 1.46 ± 0.04	3.435ThrPro: 3.435 ± 0.066	1.648ThrGln: 1.648 ± 0.036	3.515ThrArg: 3.515 ± 0.058	3.039ThrSer: 3.039 ± 0.058	3.078ThrThr: 3.078 ± 0.076	4.483ThrVal: 4.483 ± 0.122	0.641ThrTrp: 0.641 ± 0.026	1.273ThrTyr: 1.273 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	8.465ValAla: 8.465 ± 0.089	0.622ValCys: 0.622 ± 0.022	4.332ValAsp: 4.332 ± 0.076	4.639ValGlu: 4.639 ± 0.076	2.955ValPhe: 2.955 ± 0.057	5.584ValGly: 5.584 ± 0.077	1.24ValHis: 1.24 ± 0.03	4.356ValIle: 4.356 ± 0.071	2.183ValLys: 2.183 ± 0.05	7.521ValLeu: 7.521 ± 0.097	2.057ValMet: 2.057 ± 0.047	2.101ValAsn: 2.101 ± 0.057	3.621ValPro: 3.621 ± 0.056	2.212ValGln: 2.212 ± 0.043	4.131ValArg: 4.131 ± 0.07	4.672ValSer: 4.672 ± 0.069	4.926ValThr: 4.926 ± 0.138	5.688ValVal: 5.688 ± 0.087	0.911ValTrp: 0.911 ± 0.031	1.585ValTyr: 1.585 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.261TrpAla: 1.261 ± 0.042	0.142TrpCys: 0.142 ± 0.009	0.766TrpAsp: 0.766 ± 0.027	0.612TrpGlu: 0.612 ± 0.021	0.556TrpPhe: 0.556 ± 0.021	0.996TrpGly: 0.996 ± 0.027	0.333TrpHis: 0.333 ± 0.019	0.696TrpIle: 0.696 ± 0.029	0.46TrpLys: 0.46 ± 0.019	1.547TrpLeu: 1.547 ± 0.04	0.419TrpMet: 0.419 ± 0.021	0.493TrpAsn: 0.493 ± 0.022	0.683TrpPro: 0.683 ± 0.026	0.616TrpGln: 0.616 ± 0.025	1.006TrpArg: 1.006 ± 0.03	0.827TrpSer: 0.827 ± 0.028	0.79TrpThr: 0.79 ± 0.027	0.863TrpVal: 0.863 ± 0.028	0.228TrpTrp: 0.228 ± 0.015	0.272TrpTyr: 0.272 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.455TyrAla: 2.455 ± 0.045	0.242TyrCys: 0.242 ± 0.015	1.627TyrAsp: 1.627 ± 0.043	1.319TyrGlu: 1.319 ± 0.034	0.949TyrPhe: 0.949 ± 0.03	2.085TyrGly: 2.085 ± 0.039	0.504TyrHis: 0.504 ± 0.021	0.995TyrIle: 0.995 ± 0.029	0.574TyrLys: 0.574 ± 0.021	2.355TyrLeu: 2.355 ± 0.046	0.509TyrMet: 0.509 ± 0.022	0.625TyrAsn: 0.625 ± 0.023	1.163TyrPro: 1.163 ± 0.033	0.715TyrGln: 0.715 ± 0.026	1.578TyrArg: 1.578 ± 0.039	1.283TyrSer: 1.283 ± 0.032	1.156TyrThr: 1.156 ± 0.048	1.632TyrVal: 1.632 ± 0.035	0.384TyrTrp: 0.384 ± 0.018	0.607TyrTyr: 0.607 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3573 proteins (1157484 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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