Amino acid dipepetide frequency for Capronia coronata CBS 617.96

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.373AlaAla: 9.373 ± 0.064	1.024AlaCys: 1.024 ± 0.017	4.49AlaAsp: 4.49 ± 0.036	5.42AlaGlu: 5.42 ± 0.042	3.097AlaPhe: 3.097 ± 0.027	6.156AlaGly: 6.156 ± 0.038	1.867AlaHis: 1.867 ± 0.021	4.148AlaIle: 4.148 ± 0.036	4.107AlaLys: 4.107 ± 0.037	7.718AlaLeu: 7.718 ± 0.051	1.999AlaMet: 1.999 ± 0.022	2.973AlaAsn: 2.973 ± 0.023	4.741AlaPro: 4.741 ± 0.047	3.68AlaGln: 3.68 ± 0.035	5.307AlaArg: 5.307 ± 0.034	7.503AlaSer: 7.503 ± 0.055	5.56AlaThr: 5.56 ± 0.04	5.601AlaVal: 5.601 ± 0.038	1.132AlaTrp: 1.132 ± 0.016	2.168AlaTyr: 2.168 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.912CysAla: 0.912 ± 0.016	0.206CysCys: 0.206 ± 0.007	0.593CysAsp: 0.593 ± 0.012	0.536CysGlu: 0.536 ± 0.011	0.498CysPhe: 0.498 ± 0.01	0.86CysGly: 0.86 ± 0.015	0.328CysHis: 0.328 ± 0.008	0.64CysIle: 0.64 ± 0.011	0.464CysLys: 0.464 ± 0.011	1.209CysLeu: 1.209 ± 0.018	0.246CysMet: 0.246 ± 0.007	0.363CysAsn: 0.363 ± 0.009	0.612CysPro: 0.612 ± 0.013	0.413CysGln: 0.413 ± 0.01	0.714CysArg: 0.714 ± 0.013	0.803CysSer: 0.803 ± 0.016	0.624CysThr: 0.624 ± 0.012	0.747CysVal: 0.747 ± 0.014	0.183CysTrp: 0.183 ± 0.007	0.344CysTyr: 0.344 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.818AspAla: 4.818 ± 0.037	0.581AspCys: 0.581 ± 0.011	4.426AspAsp: 4.426 ± 0.051	4.571AspGlu: 4.571 ± 0.047	2.206AspPhe: 2.206 ± 0.02	4.136AspGly: 4.136 ± 0.035	1.376AspHis: 1.376 ± 0.018	2.902AspIle: 2.902 ± 0.025	2.421AspLys: 2.421 ± 0.025	5.259AspLeu: 5.259 ± 0.042	1.279AspMet: 1.279 ± 0.019	1.855AspAsn: 1.855 ± 0.019	3.511AspPro: 3.511 ± 0.027	2.075AspGln: 2.075 ± 0.021	3.258AspArg: 3.258 ± 0.035	4.142AspSer: 4.142 ± 0.034	3.046AspThr: 3.046 ± 0.027	3.79AspVal: 3.79 ± 0.031	0.886AspTrp: 0.886 ± 0.014	1.588AspTyr: 1.588 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.547GluAla: 5.547 ± 0.042	0.564GluCys: 0.564 ± 0.012	4.32GluAsp: 4.32 ± 0.041	5.362GluGlu: 5.362 ± 0.058	1.809GluPhe: 1.809 ± 0.02	3.675GluGly: 3.675 ± 0.031	1.451GluHis: 1.451 ± 0.019	2.969GluIle: 2.969 ± 0.029	3.562GluLys: 3.562 ± 0.037	5.069GluLeu: 5.069 ± 0.043	1.457GluMet: 1.457 ± 0.02	2.077GluAsn: 2.077 ± 0.023	2.848GluPro: 2.848 ± 0.031	2.66GluGln: 2.66 ± 0.03	3.993GluArg: 3.993 ± 0.035	4.186GluSer: 4.186 ± 0.034	3.538GluThr: 3.538 ± 0.028	3.709GluVal: 3.709 ± 0.031	0.821GluTrp: 0.821 ± 0.015	1.606GluTyr: 1.606 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.021PheAla: 3.021 ± 0.03	0.533PheCys: 0.533 ± 0.012	2.264PheAsp: 2.264 ± 0.023	2.093PheGlu: 2.093 ± 0.022	1.557PhePhe: 1.557 ± 0.023	2.838PheGly: 2.838 ± 0.034	0.873PheHis: 0.873 ± 0.015	1.641PheIle: 1.641 ± 0.02	1.405PheLys: 1.405 ± 0.02	3.35PheLeu: 3.35 ± 0.038	0.775PheMet: 0.775 ± 0.013	1.311PheAsn: 1.311 ± 0.021	1.902PhePro: 1.902 ± 0.021	1.365PheGln: 1.365 ± 0.019	1.921PheArg: 1.921 ± 0.023	2.818PheSer: 2.818 ± 0.028	1.995PheThr: 1.995 ± 0.021	2.388PheVal: 2.388 ± 0.025	0.613PheTrp: 0.613 ± 0.012	1.051PheTyr: 1.051 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.349GlyAla: 5.349 ± 0.035	0.776GlyCys: 0.776 ± 0.016	3.679GlyAsp: 3.679 ± 0.032	3.562GlyGlu: 3.562 ± 0.028	2.753GlyPhe: 2.753 ± 0.028	5.793GlyGly: 5.793 ± 0.06	1.792GlyHis: 1.792 ± 0.023	3.396GlyIle: 3.396 ± 0.035	3.375GlyLys: 3.375 ± 0.028	6.21GlyLeu: 6.21 ± 0.039	1.676GlyMet: 1.676 ± 0.022	2.374GlyAsn: 2.374 ± 0.025	3.509GlyPro: 3.509 ± 0.038	2.813GlyGln: 2.813 ± 0.029	4.308GlyArg: 4.308 ± 0.037	5.768GlySer: 5.768 ± 0.044	4.1GlyThr: 4.1 ± 0.033	4.443GlyVal: 4.443 ± 0.034	1.141GlyTrp: 1.141 ± 0.016	2.101GlyTyr: 2.101 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.973HisAla: 1.973 ± 0.022	0.293HisCys: 0.293 ± 0.008	1.491HisAsp: 1.491 ± 0.018	1.452HisGlu: 1.452 ± 0.018	0.9HisPhe: 0.9 ± 0.014	1.836HisGly: 1.836 ± 0.021	0.896HisHis: 0.896 ± 0.017	1.147HisIle: 1.147 ± 0.017	0.954HisLys: 0.954 ± 0.017	2.271HisLeu: 2.271 ± 0.022	0.486HisMet: 0.486 ± 0.011	0.849HisAsn: 0.849 ± 0.013	1.713HisPro: 1.713 ± 0.022	1.028HisGln: 1.028 ± 0.016	1.554HisArg: 1.554 ± 0.021	1.866HisSer: 1.866 ± 0.024	1.291HisThr: 1.291 ± 0.018	1.534HisVal: 1.534 ± 0.019	0.337HisTrp: 0.337 ± 0.009	0.679HisTyr: 0.679 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.049IleAla: 4.049 ± 0.037	0.703IleCys: 0.703 ± 0.013	2.816IleAsp: 2.816 ± 0.027	2.731IleGlu: 2.731 ± 0.025	1.858IlePhe: 1.858 ± 0.024	3.062IleGly: 3.062 ± 0.035	1.144IleHis: 1.144 ± 0.016	2.241IleIle: 2.241 ± 0.027	2.062IleLys: 2.062 ± 0.024	4.424IleLeu: 4.424 ± 0.037	0.968IleMet: 0.968 ± 0.015	1.681IleAsn: 1.681 ± 0.02	2.992IlePro: 2.992 ± 0.025	1.831IleGln: 1.831 ± 0.021	2.725IleArg: 2.725 ± 0.025	3.662IleSer: 3.662 ± 0.029	2.647IleThr: 2.647 ± 0.023	3.124IleVal: 3.124 ± 0.032	0.694IleTrp: 0.694 ± 0.014	1.314IleTyr: 1.314 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.368LysAla: 4.368 ± 0.034	0.461LysCys: 0.461 ± 0.011	2.797LysAsp: 2.797 ± 0.03	3.317LysGlu: 3.317 ± 0.038	1.361LysPhe: 1.361 ± 0.019	2.912LysGly: 2.912 ± 0.026	1.154LysHis: 1.154 ± 0.015	2.18LysIle: 2.18 ± 0.025	3.15LysLys: 3.15 ± 0.046	3.882LysLeu: 3.882 ± 0.035	1.001LysMet: 1.001 ± 0.017	1.579LysAsn: 1.579 ± 0.018	2.756LysPro: 2.756 ± 0.028	1.939LysGln: 1.939 ± 0.022	3.416LysArg: 3.416 ± 0.031	3.473LysSer: 3.473 ± 0.031	2.796LysThr: 2.796 ± 0.026	2.842LysVal: 2.842 ± 0.024	0.648LysTrp: 0.648 ± 0.011	1.37LysTyr: 1.37 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.943LeuAla: 7.943 ± 0.047	1.178LeuCys: 1.178 ± 0.019	5.35LeuAsp: 5.35 ± 0.038	5.462LeuGlu: 5.462 ± 0.043	3.212LeuPhe: 3.212 ± 0.033	5.837LeuGly: 5.837 ± 0.044	2.225LeuHis: 2.225 ± 0.026	3.727LeuIle: 3.727 ± 0.034	4.186LeuLys: 4.186 ± 0.036	8.244LeuLeu: 8.244 ± 0.067	1.749LeuMet: 1.749 ± 0.017	3.071LeuAsn: 3.071 ± 0.026	5.529LeuPro: 5.529 ± 0.036	3.91LeuGln: 3.91 ± 0.034	5.742LeuArg: 5.742 ± 0.041	7.147LeuSer: 7.147 ± 0.05	4.917LeuThr: 4.917 ± 0.036	5.421LeuVal: 5.421 ± 0.043	1.164LeuTrp: 1.164 ± 0.02	2.318LeuTyr: 2.318 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.309MetAla: 2.309 ± 0.025	0.229MetCys: 0.229 ± 0.008	1.239MetAsp: 1.239 ± 0.017	1.185MetGlu: 1.185 ± 0.016	0.743MetPhe: 0.743 ± 0.014	1.442MetGly: 1.442 ± 0.019	0.494MetHis: 0.494 ± 0.01	0.964MetIle: 0.964 ± 0.015	0.963MetLys: 0.963 ± 0.016	1.874MetLeu: 1.874 ± 0.02	0.543MetMet: 0.543 ± 0.012	0.767MetAsn: 0.767 ± 0.013	1.335MetPro: 1.335 ± 0.02	0.908MetGln: 0.908 ± 0.017	1.202MetArg: 1.202 ± 0.017	1.907MetSer: 1.907 ± 0.019	1.359MetThr: 1.359 ± 0.02	1.321MetVal: 1.321 ± 0.017	0.245MetTrp: 0.245 ± 0.007	0.542MetTyr: 0.542 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.085AsnAla: 3.085 ± 0.028	0.381AsnCys: 0.381 ± 0.012	1.943AsnAsp: 1.943 ± 0.021	1.893AsnGlu: 1.893 ± 0.022	1.242AsnPhe: 1.242 ± 0.019	2.95AsnGly: 2.95 ± 0.028	0.886AsnHis: 0.886 ± 0.015	1.871AsnIle: 1.871 ± 0.023	1.456AsnLys: 1.456 ± 0.019	3.097AsnLeu: 3.097 ± 0.029	0.786AsnMet: 0.786 ± 0.013	1.391AsnAsn: 1.391 ± 0.021	2.396AsnPro: 2.396 ± 0.027	1.283AsnGln: 1.283 ± 0.017	1.85AsnArg: 1.85 ± 0.02	2.552AsnSer: 2.552 ± 0.024	2.127AsnThr: 2.127 ± 0.024	2.365AsnVal: 2.365 ± 0.024	0.499AsnTrp: 0.499 ± 0.009	0.972AsnTyr: 0.972 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.566ProAla: 5.566 ± 0.049	0.471ProCys: 0.471 ± 0.01	3.436ProAsp: 3.436 ± 0.028	3.855ProGlu: 3.855 ± 0.035	2.033ProPhe: 2.033 ± 0.021	4.17ProGly: 4.17 ± 0.034	1.373ProHis: 1.373 ± 0.02	2.416ProIle: 2.416 ± 0.025	2.631ProLys: 2.631 ± 0.026	4.767ProLeu: 4.767 ± 0.037	1.091ProMet: 1.091 ± 0.014	2.129ProAsn: 2.129 ± 0.025	5.384ProPro: 5.384 ± 0.071	2.638ProGln: 2.638 ± 0.03	3.624ProArg: 3.624 ± 0.032	6.148ProSer: 6.148 ± 0.05	4.152ProThr: 4.152 ± 0.037	3.762ProVal: 3.762 ± 0.032	0.731ProTrp: 0.731 ± 0.014	1.541ProTyr: 1.541 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.705GlnAla: 3.705 ± 0.034	0.417GlnCys: 0.417 ± 0.01	2.227GlnAsp: 2.227 ± 0.023	2.555GlnGlu: 2.555 ± 0.029	1.262GlnPhe: 1.262 ± 0.015	2.533GlnGly: 2.533 ± 0.026	1.172GlnHis: 1.172 ± 0.017	1.936GlnIle: 1.936 ± 0.022	2.027GlnLys: 2.027 ± 0.027	3.464GlnLeu: 3.464 ± 0.034	0.895GlnMet: 0.895 ± 0.017	1.544GlnAsn: 1.544 ± 0.023	2.754GlnPro: 2.754 ± 0.031	2.583GlnGln: 2.583 ± 0.052	2.779GlnArg: 2.779 ± 0.029	3.384GlnSer: 3.384 ± 0.03	2.535GlnThr: 2.535 ± 0.024	2.236GlnVal: 2.236 ± 0.023	0.543GlnTrp: 0.543 ± 0.01	1.217GlnTyr: 1.217 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	4.928ArgAla: 4.928 ± 0.042	0.662ArgCys: 0.662 ± 0.013	3.453ArgAsp: 3.453 ± 0.034	3.841ArgGlu: 3.841 ± 0.035	2.054ArgPhe: 2.054 ± 0.022	3.741ArgGly: 3.741 ± 0.032	1.692ArgHis: 1.692 ± 0.02	2.781ArgIle: 2.781 ± 0.028	3.601ArgLys: 3.601 ± 0.031	5.613ArgLeu: 5.613 ± 0.045	1.306ArgMet: 1.306 ± 0.017	2.181ArgAsn: 2.181 ± 0.023	3.897ArgPro: 3.897 ± 0.041	2.84ArgGln: 2.84 ± 0.029	5.46ArgArg: 5.46 ± 0.053	4.958ArgSer: 4.958 ± 0.051	3.52ArgThr: 3.52 ± 0.03	3.319ArgVal: 3.319 ± 0.029	0.894ArgTrp: 0.894 ± 0.015	1.697ArgTyr: 1.697 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.913SerAla: 6.913 ± 0.047	0.782SerCys: 0.782 ± 0.014	4.238SerAsp: 4.238 ± 0.034	4.079SerGlu: 4.079 ± 0.033	2.846SerPhe: 2.846 ± 0.026	5.604SerGly: 5.604 ± 0.04	1.965SerHis: 1.965 ± 0.023	3.837SerIle: 3.837 ± 0.032	3.66SerLys: 3.66 ± 0.034	7.072SerLeu: 7.072 ± 0.044	1.749SerMet: 1.749 ± 0.02	2.941SerAsn: 2.941 ± 0.027	5.743SerPro: 5.743 ± 0.058	3.443SerGln: 3.443 ± 0.032	5.25SerArg: 5.25 ± 0.048	9.022SerSer: 9.022 ± 0.09	6.028SerThr: 6.028 ± 0.059	4.612SerVal: 4.612 ± 0.037	1.052SerTrp: 1.052 ± 0.016	1.977SerTyr: 1.977 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.545ThrAla: 5.545 ± 0.039	0.671ThrCys: 0.671 ± 0.015	2.985ThrAsp: 2.985 ± 0.025	3.099ThrGlu: 3.099 ± 0.027	2.236ThrPhe: 2.236 ± 0.025	4.321ThrGly: 4.321 ± 0.035	1.311ThrHis: 1.311 ± 0.017	3.036ThrIle: 3.036 ± 0.029	2.621ThrLys: 2.621 ± 0.026	5.165ThrLeu: 5.165 ± 0.038	1.276ThrMet: 1.276 ± 0.018	2.149ThrAsn: 2.149 ± 0.025	4.474ThrPro: 4.474 ± 0.038	2.181ThrGln: 2.181 ± 0.024	3.238ThrArg: 3.238 ± 0.029	5.809ThrSer: 5.809 ± 0.049	4.789ThrThr: 4.789 ± 0.062	3.848ThrVal: 3.848 ± 0.034	0.808ThrTrp: 0.808 ± 0.016	1.561ThrTyr: 1.561 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.389ValAla: 5.389 ± 0.039	0.782ValCys: 0.782 ± 0.014	3.887ValAsp: 3.887 ± 0.029	3.94ValGlu: 3.94 ± 0.032	2.385ValPhe: 2.385 ± 0.023	4.143ValGly: 4.143 ± 0.035	1.44ValHis: 1.44 ± 0.019	2.842ValIle: 2.842 ± 0.029	2.937ValLys: 2.937 ± 0.031	5.665ValLeu: 5.665 ± 0.044	1.309ValMet: 1.309 ± 0.018	2.183ValAsn: 2.183 ± 0.025	3.72ValPro: 3.72 ± 0.03	2.492ValGln: 2.492 ± 0.023	3.553ValArg: 3.553 ± 0.031	4.689ValSer: 4.689 ± 0.037	3.583ValThr: 3.583 ± 0.032	4.431ValVal: 4.431 ± 0.042	0.883ValTrp: 0.883 ± 0.015	1.705ValTyr: 1.705 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.082TrpAla: 1.082 ± 0.017	0.186TrpCys: 0.186 ± 0.007	0.836TrpAsp: 0.836 ± 0.015	0.784TrpGlu: 0.784 ± 0.015	0.517TrpPhe: 0.517 ± 0.012	0.84TrpGly: 0.84 ± 0.014	0.356TrpHis: 0.356 ± 0.009	0.728TrpIle: 0.728 ± 0.013	0.761TrpLys: 0.761 ± 0.013	1.331TrpLeu: 1.331 ± 0.019	0.366TrpMet: 0.366 ± 0.009	0.572TrpAsn: 0.572 ± 0.012	0.608TrpPro: 0.608 ± 0.011	0.583TrpGln: 0.583 ± 0.01	0.949TrpArg: 0.949 ± 0.014	1.025TrpSer: 1.025 ± 0.016	0.94TrpThr: 0.94 ± 0.014	0.827TrpVal: 0.827 ± 0.014	0.27TrpTrp: 0.27 ± 0.007	0.411TrpTyr: 0.411 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.191TyrAla: 2.191 ± 0.022	0.394TyrCys: 0.394 ± 0.01	1.655TyrAsp: 1.655 ± 0.019	1.487TyrGlu: 1.487 ± 0.02	1.147TyrPhe: 1.147 ± 0.018	2.067TyrGly: 2.067 ± 0.026	0.756TyrHis: 0.756 ± 0.013	1.329TyrIle: 1.329 ± 0.019	1.058TyrLys: 1.058 ± 0.015	2.647TyrLeu: 2.647 ± 0.026	0.614TyrMet: 0.614 ± 0.009	1.036TyrAsn: 1.036 ± 0.015	1.496TyrPro: 1.496 ± 0.021	1.101TyrGln: 1.101 ± 0.016	1.595TyrArg: 1.595 ± 0.019	1.949TyrSer: 1.949 ± 0.023	1.576TyrThr: 1.576 ± 0.02	1.639TyrVal: 1.639 ± 0.017	0.426TyrTrp: 0.426 ± 0.01	0.893TyrTyr: 0.893 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.003

Statistics based on 9230 proteins (4650262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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