Amino acid dipepetide frequency for Suillus luteus UH-Slu-Lm8-n1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.349AlaAla: 7.349 ± 0.048	1.275AlaCys: 1.275 ± 0.015	3.878AlaAsp: 3.878 ± 0.027	4.258AlaGlu: 4.258 ± 0.029	3.251AlaPhe: 3.251 ± 0.025	4.71AlaGly: 4.71 ± 0.031	2.129AlaHis: 2.129 ± 0.02	4.276AlaIle: 4.276 ± 0.028	3.527AlaLys: 3.527 ± 0.029	8.344AlaLeu: 8.344 ± 0.044	1.879AlaMet: 1.879 ± 0.02	2.66AlaAsn: 2.66 ± 0.02	4.501AlaPro: 4.501 ± 0.035	3.281AlaGln: 3.281 ± 0.025	5.026AlaArg: 5.026 ± 0.032	7.297AlaSer: 7.297 ± 0.045	4.845AlaThr: 4.845 ± 0.032	5.315AlaVal: 5.315 ± 0.029	1.154AlaTrp: 1.154 ± 0.015	2.068AlaTyr: 2.068 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.156CysAla: 1.156 ± 0.015	0.36CysCys: 0.36 ± 0.01	0.784CysAsp: 0.784 ± 0.012	0.665CysGlu: 0.665 ± 0.011	0.68CysPhe: 0.68 ± 0.011	1.028CysGly: 1.028 ± 0.012	0.489CysHis: 0.489 ± 0.011	0.932CysIle: 0.932 ± 0.015	0.599CysLys: 0.599 ± 0.01	1.535CysLeu: 1.535 ± 0.017	0.396CysMet: 0.396 ± 0.008	0.534CysAsn: 0.534 ± 0.01	0.934CysPro: 0.934 ± 0.013	0.558CysGln: 0.558 ± 0.01	0.949CysArg: 0.949 ± 0.012	1.311CysSer: 1.311 ± 0.015	0.91CysThr: 0.91 ± 0.013	0.974CysVal: 0.974 ± 0.013	0.257CysTrp: 0.257 ± 0.007	0.402CysTyr: 0.402 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.641AspAla: 4.641 ± 0.031	0.718AspCys: 0.718 ± 0.013	4.182AspAsp: 4.182 ± 0.04	4.127AspGlu: 4.127 ± 0.029	2.117AspPhe: 2.117 ± 0.021	3.938AspGly: 3.938 ± 0.033	1.445AspHis: 1.445 ± 0.018	3.362AspIle: 3.362 ± 0.023	2.171AspLys: 2.171 ± 0.021	5.015AspLeu: 5.015 ± 0.032	1.215AspMet: 1.215 ± 0.013	1.81AspAsn: 1.81 ± 0.018	3.149AspPro: 3.149 ± 0.025	1.689AspGln: 1.689 ± 0.02	2.909AspArg: 2.909 ± 0.023	4.091AspSer: 4.091 ± 0.031	3.098AspThr: 3.098 ± 0.025	3.967AspVal: 3.967 ± 0.028	0.945AspTrp: 0.945 ± 0.016	1.411AspTyr: 1.411 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.496GluAla: 4.496 ± 0.035	0.752GluCys: 0.752 ± 0.011	3.906GluAsp: 3.906 ± 0.031	4.61GluGlu: 4.61 ± 0.042	1.868GluPhe: 1.868 ± 0.02	3.317GluGly: 3.317 ± 0.027	1.506GluHis: 1.506 ± 0.014	2.808GluIle: 2.808 ± 0.023	2.761GluLys: 2.761 ± 0.023	5.198GluLeu: 5.198 ± 0.033	1.28GluMet: 1.28 ± 0.016	1.896GluAsn: 1.896 ± 0.018	2.453GluPro: 2.453 ± 0.025	2.084GluGln: 2.084 ± 0.019	3.693GluArg: 3.693 ± 0.03	3.968GluSer: 3.968 ± 0.026	2.92GluThr: 2.92 ± 0.025	3.512GluVal: 3.512 ± 0.029	0.902GluTrp: 0.902 ± 0.013	1.451GluTyr: 1.451 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.058PheAla: 3.058 ± 0.027	0.646PheCys: 0.646 ± 0.012	2.266PheAsp: 2.266 ± 0.023	2.009PheGlu: 2.009 ± 0.02	1.602PhePhe: 1.602 ± 0.019	2.609PheGly: 2.609 ± 0.028	1.081PheHis: 1.081 ± 0.015	2.005PheIle: 2.005 ± 0.018	1.578PheLys: 1.578 ± 0.018	3.669PheLeu: 3.669 ± 0.03	0.885PheMet: 0.885 ± 0.013	1.429PheAsn: 1.429 ± 0.017	2.069PhePro: 2.069 ± 0.02	1.308PheGln: 1.308 ± 0.015	2.073PheArg: 2.073 ± 0.02	3.391PheSer: 3.391 ± 0.024	2.309PheThr: 2.309 ± 0.019	2.565PheVal: 2.565 ± 0.025	0.633PheTrp: 0.633 ± 0.009	1.083PheTyr: 1.083 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.398GlyAla: 4.398 ± 0.031	0.968GlyCys: 0.968 ± 0.015	3.258GlyAsp: 3.258 ± 0.026	3.232GlyGlu: 3.232 ± 0.026	2.383GlyPhe: 2.383 ± 0.023	4.455GlyGly: 4.455 ± 0.034	1.935GlyHis: 1.935 ± 0.022	3.277GlyIle: 3.277 ± 0.029	3.176GlyLys: 3.176 ± 0.027	5.272GlyLeu: 5.272 ± 0.032	1.454GlyMet: 1.454 ± 0.022	2.118GlyAsn: 2.118 ± 0.02	2.9GlyPro: 2.9 ± 0.026	2.187GlyGln: 2.187 ± 0.022	3.756GlyArg: 3.756 ± 0.028	5.274GlySer: 5.274 ± 0.034	3.709GlyThr: 3.709 ± 0.029	4.001GlyVal: 4.001 ± 0.029	1.005GlyTrp: 1.005 ± 0.014	1.712GlyTyr: 1.712 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	2.315HisAla: 2.315 ± 0.021	0.497HisCys: 0.497 ± 0.01	1.548HisAsp: 1.548 ± 0.017	1.409HisGlu: 1.409 ± 0.016	1.129HisPhe: 1.129 ± 0.015	1.701HisGly: 1.701 ± 0.018	1.046HisHis: 1.046 ± 0.016	1.601HisIle: 1.601 ± 0.016	0.997HisLys: 0.997 ± 0.011	2.762HisLeu: 2.762 ± 0.023	0.587HisMet: 0.587 ± 0.01	0.975HisAsn: 0.975 ± 0.015	2.038HisPro: 2.038 ± 0.023	1.09HisGln: 1.09 ± 0.014	1.802HisArg: 1.802 ± 0.02	2.512HisSer: 2.512 ± 0.023	1.787HisThr: 1.787 ± 0.02	1.793HisVal: 1.793 ± 0.019	0.402HisTrp: 0.402 ± 0.009	0.736HisTyr: 0.736 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.376IleAla: 4.376 ± 0.029	0.914IleCys: 0.914 ± 0.013	2.901IleAsp: 2.901 ± 0.021	2.694IleGlu: 2.694 ± 0.025	2.139IlePhe: 2.139 ± 0.021	2.958IleGly: 2.958 ± 0.025	1.429IleHis: 1.429 ± 0.017	2.884IleIle: 2.884 ± 0.022	2.158IleLys: 2.158 ± 0.019	4.925IleLeu: 4.925 ± 0.033	1.158IleMet: 1.158 ± 0.013	1.826IleAsn: 1.826 ± 0.019	3.372IlePro: 3.372 ± 0.023	1.986IleGln: 1.986 ± 0.018	3.059IleArg: 3.059 ± 0.023	4.477IleSer: 4.477 ± 0.028	3.075IleThr: 3.075 ± 0.022	3.386IleVal: 3.386 ± 0.024	0.851IleTrp: 0.851 ± 0.013	1.444IleTyr: 1.444 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.683LysAla: 3.683 ± 0.033	0.604LysCys: 0.604 ± 0.011	2.509LysAsp: 2.509 ± 0.024	2.827LysGlu: 2.827 ± 0.029	1.479LysPhe: 1.479 ± 0.016	2.567LysGly: 2.567 ± 0.025	1.266LysHis: 1.266 ± 0.017	2.066LysIle: 2.066 ± 0.02	2.835LysLys: 2.835 ± 0.028	4.067LysLeu: 4.067 ± 0.03	0.955LysMet: 0.955 ± 0.013	1.52LysAsn: 1.52 ± 0.016	2.326LysPro: 2.326 ± 0.019	1.632LysGln: 1.632 ± 0.017	3.281LysArg: 3.281 ± 0.028	3.331LysSer: 3.331 ± 0.027	2.638LysThr: 2.638 ± 0.021	2.66LysVal: 2.66 ± 0.025	0.636LysTrp: 0.636 ± 0.01	1.247LysTyr: 1.247 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.055LeuAla: 8.055 ± 0.044	1.611LeuCys: 1.611 ± 0.019	5.325LeuAsp: 5.325 ± 0.035	5.202LeuGlu: 5.202 ± 0.034	3.514LeuPhe: 3.514 ± 0.029	5.355LeuGly: 5.355 ± 0.034	2.786LeuHis: 2.786 ± 0.023	4.297LeuIle: 4.297 ± 0.033	4.134LeuLys: 4.134 ± 0.026	9.039LeuLeu: 9.039 ± 0.057	1.935LeuMet: 1.935 ± 0.018	3.201LeuAsn: 3.201 ± 0.023	6.133LeuPro: 6.133 ± 0.039	3.993LeuGln: 3.993 ± 0.03	6.075LeuArg: 6.075 ± 0.035	8.473LeuSer: 8.473 ± 0.047	5.336LeuThr: 5.336 ± 0.035	5.768LeuVal: 5.768 ± 0.037	1.417LeuTrp: 1.417 ± 0.017	2.441LeuTyr: 2.441 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.81MetAla: 1.81 ± 0.018	0.314MetCys: 0.314 ± 0.008	1.272MetAsp: 1.272 ± 0.015	1.19MetGlu: 1.19 ± 0.014	0.832MetPhe: 0.832 ± 0.012	1.282MetGly: 1.282 ± 0.018	0.665MetHis: 0.665 ± 0.01	1.132MetIle: 1.132 ± 0.015	1.046MetLys: 1.046 ± 0.013	2.007MetLeu: 2.007 ± 0.017	0.59MetMet: 0.59 ± 0.012	0.842MetAsn: 0.842 ± 0.015	1.27MetPro: 1.27 ± 0.016	0.925MetGln: 0.925 ± 0.014	1.352MetArg: 1.352 ± 0.015	2.139MetSer: 2.139 ± 0.019	1.42MetThr: 1.42 ± 0.015	1.285MetVal: 1.285 ± 0.013	0.286MetTrp: 0.286 ± 0.007	0.591MetTyr: 0.591 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.012AsnAla: 3.012 ± 0.023	0.486AsnCys: 0.486 ± 0.01	1.925AsnAsp: 1.925 ± 0.018	1.755AsnGlu: 1.755 ± 0.017	1.391AsnPhe: 1.391 ± 0.015	2.338AsnGly: 2.338 ± 0.021	0.979AsnHis: 0.979 ± 0.014	2.145AsnIle: 2.145 ± 0.019	1.371AsnLys: 1.371 ± 0.015	3.287AsnLeu: 3.287 ± 0.031	0.815AsnMet: 0.815 ± 0.012	1.4AsnAsn: 1.4 ± 0.016	2.185AsnPro: 2.185 ± 0.021	1.196AsnGln: 1.196 ± 0.015	1.75AsnArg: 1.75 ± 0.016	2.805AsnSer: 2.805 ± 0.022	2.219AsnThr: 2.219 ± 0.021	2.398AsnVal: 2.398 ± 0.02	0.512AsnTrp: 0.512 ± 0.011	0.935AsnTyr: 0.935 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.771ProAla: 4.771 ± 0.033	0.7ProCys: 0.7 ± 0.011	3.245ProAsp: 3.245 ± 0.026	3.162ProGlu: 3.162 ± 0.027	2.178ProPhe: 2.178 ± 0.02	3.338ProGly: 3.338 ± 0.026	1.694ProHis: 1.694 ± 0.019	2.825ProIle: 2.825 ± 0.024	2.295ProLys: 2.295 ± 0.022	5.315ProLeu: 5.315 ± 0.037	1.092ProMet: 1.092 ± 0.015	2.16ProAsn: 2.16 ± 0.021	5.725ProPro: 5.725 ± 0.062	2.407ProGln: 2.407 ± 0.028	3.468ProArg: 3.468 ± 0.027	7.026ProSer: 7.026 ± 0.053	4.128ProThr: 4.128 ± 0.034	3.719ProVal: 3.719 ± 0.023	0.74ProTrp: 0.74 ± 0.012	1.515ProTyr: 1.515 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.141GlnAla: 3.141 ± 0.025	0.601GlnCys: 0.601 ± 0.011	1.968GlnAsp: 1.968 ± 0.019	2.131GlnGlu: 2.131 ± 0.02	1.313GlnPhe: 1.313 ± 0.016	2.138GlnGly: 2.138 ± 0.02	1.214GlnHis: 1.214 ± 0.013	1.857GlnIle: 1.857 ± 0.019	1.653GlnLys: 1.653 ± 0.016	3.57GlnLeu: 3.57 ± 0.026	0.842GlnMet: 0.842 ± 0.013	1.376GlnAsn: 1.376 ± 0.016	2.465GlnPro: 2.465 ± 0.028	1.936GlnGln: 1.936 ± 0.033	2.623GlnArg: 2.623 ± 0.024	3.219GlnSer: 3.219 ± 0.026	2.305GlnThr: 2.305 ± 0.023	2.241GlnVal: 2.241 ± 0.021	0.628GlnTrp: 0.628 ± 0.009	1.072GlnTyr: 1.072 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.802ArgAla: 4.802 ± 0.037	0.99ArgCys: 0.99 ± 0.013	3.284ArgAsp: 3.284 ± 0.028	3.572ArgGlu: 3.572 ± 0.028	2.298ArgPhe: 2.298 ± 0.021	3.446ArgGly: 3.446 ± 0.03	1.802ArgHis: 1.802 ± 0.02	3.181ArgIle: 3.181 ± 0.024	3.222ArgLys: 3.222 ± 0.027	5.819ArgLeu: 5.819 ± 0.034	1.474ArgMet: 1.474 ± 0.015	2.108ArgAsn: 2.108 ± 0.019	3.485ArgPro: 3.485 ± 0.031	2.433ArgGln: 2.433 ± 0.024	5.011ArgArg: 5.011 ± 0.04	5.182ArgSer: 5.182 ± 0.036	3.586ArgThr: 3.586 ± 0.029	3.75ArgVal: 3.75 ± 0.027	1.039ArgTrp: 1.039 ± 0.015	1.656ArgTyr: 1.656 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.942SerAla: 6.942 ± 0.045	1.319SerCys: 1.319 ± 0.016	4.576SerAsp: 4.576 ± 0.03	4.076SerGlu: 4.076 ± 0.027	3.439SerPhe: 3.439 ± 0.026	5.403SerGly: 5.403 ± 0.038	2.529SerHis: 2.529 ± 0.02	4.401SerIle: 4.401 ± 0.03	3.533SerLys: 3.533 ± 0.029	8.273SerLeu: 8.273 ± 0.046	1.951SerMet: 1.951 ± 0.019	3.028SerAsn: 3.028 ± 0.024	6.162SerPro: 6.162 ± 0.052	3.346SerGln: 3.346 ± 0.027	5.401SerArg: 5.401 ± 0.041	10.274SerSer: 10.274 ± 0.085	6.157SerThr: 6.157 ± 0.036	5.17SerVal: 5.17 ± 0.037	1.155SerTrp: 1.155 ± 0.013	2.203SerTyr: 2.203 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	4.755ThrAla: 4.755 ± 0.032	0.966ThrCys: 0.966 ± 0.015	2.791ThrAsp: 2.791 ± 0.023	2.707ThrGlu: 2.707 ± 0.024	2.405ThrPhe: 2.405 ± 0.021	3.774ThrGly: 3.774 ± 0.032	1.71ThrHis: 1.71 ± 0.017	3.313ThrIle: 3.313 ± 0.027	2.423ThrLys: 2.423 ± 0.02	5.862ThrLeu: 5.862 ± 0.036	1.285ThrMet: 1.285 ± 0.014	2.087ThrAsn: 2.087 ± 0.021	4.398ThrPro: 4.398 ± 0.033	2.228ThrGln: 2.228 ± 0.024	3.62ThrArg: 3.62 ± 0.027	6.043ThrSer: 6.043 ± 0.044	4.208ThrThr: 4.208 ± 0.032	3.77ThrVal: 3.77 ± 0.027	0.901ThrTrp: 0.901 ± 0.014	1.625ThrTyr: 1.625 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.092ValAla: 5.092 ± 0.03	1.005ValCys: 1.005 ± 0.015	3.69ValAsp: 3.69 ± 0.026	3.581ValGlu: 3.581 ± 0.026	2.529ValPhe: 2.529 ± 0.024	3.623ValGly: 3.623 ± 0.027	1.774ValHis: 1.774 ± 0.017	3.411ValIle: 3.411 ± 0.026	2.798ValLys: 2.798 ± 0.025	6.18ValLeu: 6.18 ± 0.039	1.472ValMet: 1.472 ± 0.016	2.203ValAsn: 2.203 ± 0.022	3.816ValPro: 3.816 ± 0.031	2.439ValGln: 2.439 ± 0.022	3.699ValArg: 3.699 ± 0.025	5.166ValSer: 5.166 ± 0.038	3.622ValThr: 3.622 ± 0.028	4.512ValVal: 4.512 ± 0.037	1.053ValTrp: 1.053 ± 0.014	1.694ValTyr: 1.694 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.092TrpAla: 1.092 ± 0.013	0.275TrpCys: 0.275 ± 0.006	1.074TrpAsp: 1.074 ± 0.017	0.852TrpGlu: 0.852 ± 0.011	0.538TrpPhe: 0.538 ± 0.01	0.8TrpGly: 0.8 ± 0.013	0.419TrpHis: 0.419 ± 0.009	0.777TrpIle: 0.777 ± 0.012	0.805TrpLys: 0.805 ± 0.012	1.379TrpLeu: 1.379 ± 0.027	0.399TrpMet: 0.399 ± 0.008	0.72TrpAsn: 0.72 ± 0.013	0.613TrpPro: 0.613 ± 0.011	0.577TrpGln: 0.577 ± 0.009	1.02TrpArg: 1.02 ± 0.014	1.216TrpSer: 1.216 ± 0.016	0.997TrpThr: 0.997 ± 0.015	0.929TrpVal: 0.929 ± 0.014	0.305TrpTrp: 0.305 ± 0.008	0.432TrpTyr: 0.432 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.078TyrAla: 2.078 ± 0.02	0.453TyrCys: 0.453 ± 0.009	1.616TyrAsp: 1.616 ± 0.017	1.32TyrGlu: 1.32 ± 0.014	1.182TyrPhe: 1.182 ± 0.016	1.69TyrGly: 1.69 ± 0.018	0.831TyrHis: 0.831 ± 0.011	1.463TyrIle: 1.463 ± 0.016	1.048TyrLys: 1.048 ± 0.014	2.573TyrLeu: 2.573 ± 0.023	0.585TyrMet: 0.585 ± 0.01	1.009TyrAsn: 1.009 ± 0.014	1.506TyrPro: 1.506 ± 0.018	1.0TyrGln: 1.0 ± 0.013	1.573TyrArg: 1.573 ± 0.018	2.143TyrSer: 2.143 ± 0.019	1.602TyrThr: 1.602 ± 0.02	1.645TyrVal: 1.645 ± 0.018	0.401TyrTrp: 0.401 ± 0.009	0.842TyrTyr: 0.842 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 18277 proteins (5969091 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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