Amino acid dipepetide frequency for Oat golden stripe virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.93AlaAla: 5.93 ± 2.288
0.439AlaCys: 0.439 ± 0.557
3.514AlaAsp: 3.514 ± 1.972
5.711AlaGlu: 5.711 ± 2.189
1.977AlaPhe: 1.977 ± 0.66
2.636AlaGly: 2.636 ± 0.538
1.318AlaHis: 1.318 ± 0.249
2.855AlaIle: 2.855 ± 0.463
5.711AlaLys: 5.711 ± 0.813
7.687AlaLeu: 7.687 ± 0.871
3.295AlaMet: 3.295 ± 0.399
2.196AlaAsn: 2.196 ± 0.599
3.514AlaPro: 3.514 ± 0.528
1.977AlaGln: 1.977 ± 0.543
3.075AlaArg: 3.075 ± 0.454
5.271AlaSer: 5.271 ± 1.053
3.295AlaThr: 3.295 ± 1.025
5.491AlaVal: 5.491 ± 1.267
0.22AlaTrp: 0.22 ± 0.461
2.196AlaTyr: 2.196 ± 0.243
0.22AlaXaa: 0.22 ± 0.248
Cys
1.098CysAla: 1.098 ± 0.88
0.879CysCys: 0.879 ± 0.337
1.098CysAsp: 1.098 ± 0.545
2.196CysGlu: 2.196 ± 0.843
0.659CysPhe: 0.659 ± 0.343
1.977CysGly: 1.977 ± 0.742
0.439CysHis: 0.439 ± 0.169
0.439CysIle: 0.439 ± 0.169
1.098CysLys: 1.098 ± 0.421
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.439CysAsn: 0.439 ± 0.169
0.879CysPro: 0.879 ± 0.337
1.098CysGln: 1.098 ± 0.421
0.659CysArg: 0.659 ± 0.891
0.439CysSer: 0.439 ± 0.239
0.439CysThr: 0.439 ± 0.312
2.636CysVal: 2.636 ± 0.705
0.0CysTrp: 0.0 ± 0.0
1.318CysTyr: 1.318 ± 0.732
0.0CysXaa: 0.0 ± 0.0
Asp
5.052AspAla: 5.052 ± 1.251
1.318AspCys: 1.318 ± 0.538
7.907AspAsp: 7.907 ± 1.854
4.393AspGlu: 4.393 ± 0.879
1.977AspPhe: 1.977 ± 0.71
3.953AspGly: 3.953 ± 0.749
0.879AspHis: 0.879 ± 0.337
3.295AspIle: 3.295 ± 0.519
3.734AspLys: 3.734 ± 0.761
7.468AspLeu: 7.468 ± 0.908
1.098AspMet: 1.098 ± 0.421
1.318AspAsn: 1.318 ± 0.381
0.879AspPro: 0.879 ± 0.624
1.098AspGln: 1.098 ± 0.965
4.832AspArg: 4.832 ± 0.916
5.271AspSer: 5.271 ± 0.773
2.196AspThr: 2.196 ± 0.687
6.589AspVal: 6.589 ± 0.892
0.659AspTrp: 0.659 ± 0.269
1.977AspTyr: 1.977 ± 0.572
0.0AspXaa: 0.0 ± 0.0
Glu
4.612GluAla: 4.612 ± 0.748
0.659GluCys: 0.659 ± 0.639
4.173GluAsp: 4.173 ± 1.081
3.953GluGlu: 3.953 ± 0.538
2.636GluPhe: 2.636 ± 0.564
3.075GluGly: 3.075 ± 2.142
1.757GluHis: 1.757 ± 0.467
3.295GluIle: 3.295 ± 0.676
6.589GluLys: 6.589 ± 1.215
8.785GluLeu: 8.785 ± 0.989
2.636GluMet: 2.636 ± 0.548
4.173GluAsn: 4.173 ± 0.687
1.318GluPro: 1.318 ± 0.249
1.318GluGln: 1.318 ± 0.28
4.173GluArg: 4.173 ± 0.731
4.393GluSer: 4.393 ± 0.827
3.295GluThr: 3.295 ± 1.194
9.444GluVal: 9.444 ± 1.527
0.879GluTrp: 0.879 ± 0.415
1.977GluTyr: 1.977 ± 0.746
0.0GluXaa: 0.0 ± 0.0
Phe
2.636PheAla: 2.636 ± 0.656
1.318PheCys: 1.318 ± 0.562
3.075PheAsp: 3.075 ± 1.08
2.196PheGlu: 2.196 ± 0.553
1.537PhePhe: 1.537 ± 0.443
2.636PheGly: 2.636 ± 0.807
1.098PheHis: 1.098 ± 0.27
2.196PheIle: 2.196 ± 0.878
1.537PheLys: 1.537 ± 0.582
3.295PheLeu: 3.295 ± 1.047
1.098PheMet: 1.098 ± 0.372
1.537PheAsn: 1.537 ± 0.455
1.537PhePro: 1.537 ± 0.437
0.659PheGln: 0.659 ± 0.589
1.977PheArg: 1.977 ± 0.558
3.734PheSer: 3.734 ± 0.719
1.977PheThr: 1.977 ± 0.812
3.295PheVal: 3.295 ± 0.519
0.22PheTrp: 0.22 ± 0.248
1.757PheTyr: 1.757 ± 0.686
0.0PheXaa: 0.0 ± 0.0
Gly
1.318GlyAla: 1.318 ± 0.81
0.439GlyCys: 0.439 ± 0.169
3.514GlyAsp: 3.514 ± 0.899
5.93GlyGlu: 5.93 ± 1.412
2.416GlyPhe: 2.416 ± 0.699
3.953GlyGly: 3.953 ± 1.079
0.659GlyHis: 0.659 ± 0.385
1.318GlyIle: 1.318 ± 0.451
5.271GlyLys: 5.271 ± 1.991
3.075GlyLeu: 3.075 ± 0.464
1.757GlyMet: 1.757 ± 0.87
3.295GlyAsn: 3.295 ± 0.55
1.098GlyPro: 1.098 ± 0.392
1.977GlyGln: 1.977 ± 1.401
2.416GlyArg: 2.416 ± 0.649
4.832GlySer: 4.832 ± 0.78
3.514GlyThr: 3.514 ± 1.488
3.734GlyVal: 3.734 ± 0.932
0.659GlyTrp: 0.659 ± 0.639
2.196GlyTyr: 2.196 ± 1.363
0.0GlyXaa: 0.0 ± 0.0
His
2.416HisAla: 2.416 ± 0.943
0.879HisCys: 0.879 ± 0.337
0.439HisAsp: 0.439 ± 0.169
1.757HisGlu: 1.757 ± 0.467
0.879HisPhe: 0.879 ± 0.337
1.537HisGly: 1.537 ± 0.405
0.0HisHis: 0.0 ± 0.0
1.318HisIle: 1.318 ± 0.381
1.537HisLys: 1.537 ± 0.582
1.318HisLeu: 1.318 ± 0.28
0.22HisMet: 0.22 ± 0.4
0.879HisAsn: 0.879 ± 0.337
0.439HisPro: 0.439 ± 0.557
0.22HisGln: 0.22 ± 0.461
1.537HisArg: 1.537 ± 0.435
1.318HisSer: 1.318 ± 0.368
1.318HisThr: 1.318 ± 0.451
1.098HisVal: 1.098 ± 0.252
0.0HisTrp: 0.0 ± 0.0
0.439HisTyr: 0.439 ± 0.169
0.0HisXaa: 0.0 ± 0.0
Ile
2.416IleAla: 2.416 ± 1.039
1.098IleCys: 1.098 ± 0.343
4.612IleAsp: 4.612 ± 1.297
2.636IleGlu: 2.636 ± 0.649
1.977IlePhe: 1.977 ± 0.644
2.636IleGly: 2.636 ± 0.641
0.879IleHis: 0.879 ± 0.39
2.636IleIle: 2.636 ± 0.324
1.318IleLys: 1.318 ± 0.328
4.393IleLeu: 4.393 ± 0.447
0.879IleMet: 0.879 ± 0.339
1.757IleAsn: 1.757 ± 0.553
1.977IlePro: 1.977 ± 1.03
1.098IleGln: 1.098 ± 0.421
2.416IleArg: 2.416 ± 0.77
3.514IleSer: 3.514 ± 0.75
3.953IleThr: 3.953 ± 0.601
2.636IleVal: 2.636 ± 0.594
0.879IleTrp: 0.879 ± 0.337
0.879IleTyr: 0.879 ± 0.337
0.0IleXaa: 0.0 ± 0.0
Lys
5.271LysAla: 5.271 ± 1.186
1.757LysCys: 1.757 ± 0.74
5.491LysAsp: 5.491 ± 1.114
4.832LysGlu: 4.832 ± 0.897
3.514LysPhe: 3.514 ± 1.212
3.514LysGly: 3.514 ± 0.655
1.318LysHis: 1.318 ± 0.492
3.953LysIle: 3.953 ± 0.745
3.953LysLys: 3.953 ± 1.293
6.15LysLeu: 6.15 ± 1.074
0.659LysMet: 0.659 ± 0.322
3.295LysAsn: 3.295 ± 0.738
3.295LysPro: 3.295 ± 1.025
1.757LysGln: 1.757 ± 0.467
5.052LysArg: 5.052 ± 1.04
4.832LysSer: 4.832 ± 0.991
4.393LysThr: 4.393 ± 0.465
4.393LysVal: 4.393 ± 0.827
1.318LysTrp: 1.318 ± 0.451
3.295LysTyr: 3.295 ± 0.43
0.22LysXaa: 0.22 ± 0.156
Leu
4.612LeuAla: 4.612 ± 1.035
0.879LeuCys: 0.879 ± 0.337
5.271LeuAsp: 5.271 ± 0.7
5.491LeuGlu: 5.491 ± 1.425
3.075LeuPhe: 3.075 ± 1.08
5.052LeuGly: 5.052 ± 2.332
1.098LeuHis: 1.098 ± 0.421
5.491LeuIle: 5.491 ± 0.757
8.127LeuLys: 8.127 ± 0.939
8.346LeuLeu: 8.346 ± 1.379
5.271LeuMet: 5.271 ± 0.907
4.832LeuAsn: 4.832 ± 1.023
2.196LeuPro: 2.196 ± 0.505
3.953LeuGln: 3.953 ± 0.757
7.248LeuArg: 7.248 ± 1.635
5.711LeuSer: 5.711 ± 1.507
4.612LeuThr: 4.612 ± 0.798
5.491LeuVal: 5.491 ± 0.748
1.318LeuTrp: 1.318 ± 0.278
2.196LeuTyr: 2.196 ± 0.588
0.0LeuXaa: 0.0 ± 0.0
Met
2.416MetAla: 2.416 ± 0.816
0.22MetCys: 0.22 ± 0.4
0.879MetAsp: 0.879 ± 0.948
2.855MetGlu: 2.855 ± 0.367
0.659MetPhe: 0.659 ± 0.269
1.098MetGly: 1.098 ± 0.364
0.879MetHis: 0.879 ± 0.337
1.098MetIle: 1.098 ± 0.78
2.636MetLys: 2.636 ± 0.656
3.295MetLeu: 3.295 ± 0.313
0.439MetMet: 0.439 ± 0.439
3.075MetAsn: 3.075 ± 1.043
1.977MetPro: 1.977 ± 0.45
0.879MetGln: 0.879 ± 0.337
1.537MetArg: 1.537 ± 0.663
1.757MetSer: 1.757 ± 1.173
1.537MetThr: 1.537 ± 0.451
0.879MetVal: 0.879 ± 0.337
0.659MetTrp: 0.659 ± 0.197
0.659MetTyr: 0.659 ± 0.744
0.0MetXaa: 0.0 ± 0.0
Asn
5.052AsnAla: 5.052 ± 0.624
2.196AsnCys: 2.196 ± 0.459
1.098AsnAsp: 1.098 ± 0.252
3.075AsnGlu: 3.075 ± 0.559
3.075AsnPhe: 3.075 ± 0.532
2.636AsnGly: 2.636 ± 0.573
1.537AsnHis: 1.537 ± 0.405
0.659AsnIle: 0.659 ± 0.802
2.416AsnLys: 2.416 ± 1.309
3.734AsnLeu: 3.734 ± 1.167
1.318AsnMet: 1.318 ± 0.495
1.537AsnAsn: 1.537 ± 0.405
1.098AsnPro: 1.098 ± 0.364
1.757AsnGln: 1.757 ± 0.315
1.098AsnArg: 1.098 ± 0.252
3.295AsnSer: 3.295 ± 0.522
2.416AsnThr: 2.416 ± 0.451
4.173AsnVal: 4.173 ± 1.615
0.439AsnTrp: 0.439 ± 0.169
1.537AsnTyr: 1.537 ± 0.814
0.0AsnXaa: 0.0 ± 0.0
Pro
3.514ProAla: 3.514 ± 1.181
1.098ProCys: 1.098 ± 0.252
2.416ProAsp: 2.416 ± 1.505
3.295ProGlu: 3.295 ± 0.262
1.098ProPhe: 1.098 ± 0.27
2.636ProGly: 2.636 ± 0.451
0.439ProHis: 0.439 ± 0.312
2.416ProIle: 2.416 ± 0.719
3.075ProLys: 3.075 ± 0.927
3.075ProLeu: 3.075 ± 0.454
0.879ProMet: 0.879 ± 0.232
0.879ProAsn: 0.879 ± 0.337
0.439ProPro: 0.439 ± 0.456
0.439ProGln: 0.439 ± 0.367
1.098ProArg: 1.098 ± 0.655
1.977ProSer: 1.977 ± 0.543
2.196ProThr: 2.196 ± 0.619
2.416ProVal: 2.416 ± 0.411
0.439ProTrp: 0.439 ± 0.169
1.098ProTyr: 1.098 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
2.196GlnAla: 2.196 ± 0.399
0.22GlnCys: 0.22 ± 0.156
2.416GlnAsp: 2.416 ± 0.847
2.196GlnGlu: 2.196 ± 0.687
1.098GlnPhe: 1.098 ± 0.27
1.537GlnGly: 1.537 ± 0.42
0.879GlnHis: 0.879 ± 0.415
2.416GlnIle: 2.416 ± 1.155
3.514GlnLys: 3.514 ± 0.797
3.075GlnLeu: 3.075 ± 0.403
0.659GlnMet: 0.659 ± 0.343
0.22GlnAsn: 0.22 ± 0.156
1.318GlnPro: 1.318 ± 0.451
2.196GlnGln: 2.196 ± 0.841
1.318GlnArg: 1.318 ± 0.249
1.757GlnSer: 1.757 ± 0.899
1.318GlnThr: 1.318 ± 0.793
1.537GlnVal: 1.537 ± 1.489
0.0GlnTrp: 0.0 ± 0.0
1.318GlnTyr: 1.318 ± 0.506
0.0GlnXaa: 0.0 ± 0.0
Arg
4.393ArgAla: 4.393 ± 0.771
0.439ArgCys: 0.439 ± 0.169
1.977ArgAsp: 1.977 ± 0.566
2.416ArgGlu: 2.416 ± 0.58
1.098ArgPhe: 1.098 ± 0.713
5.052ArgGly: 5.052 ± 0.459
1.977ArgHis: 1.977 ± 0.447
1.977ArgIle: 1.977 ± 0.566
5.271ArgLys: 5.271 ± 0.94
3.075ArgLeu: 3.075 ± 0.407
2.196ArgMet: 2.196 ± 0.734
3.734ArgAsn: 3.734 ± 1.546
0.879ArgPro: 0.879 ± 0.415
1.537ArgGln: 1.537 ± 0.598
3.953ArgArg: 3.953 ± 0.75
5.271ArgSer: 5.271 ± 0.842
6.809ArgThr: 6.809 ± 1.718
4.173ArgVal: 4.173 ± 0.855
1.098ArgTrp: 1.098 ± 0.421
0.659ArgTyr: 0.659 ± 0.318
0.0ArgXaa: 0.0 ± 0.0
Ser
4.612SerAla: 4.612 ± 0.757
1.318SerCys: 1.318 ± 0.492
6.369SerAsp: 6.369 ± 0.913
4.393SerGlu: 4.393 ± 1.041
3.075SerPhe: 3.075 ± 0.533
2.416SerGly: 2.416 ± 0.575
0.659SerHis: 0.659 ± 0.396
3.295SerIle: 3.295 ± 0.55
5.271SerLys: 5.271 ± 0.986
6.369SerLeu: 6.369 ± 2.015
2.416SerMet: 2.416 ± 0.443
2.416SerAsn: 2.416 ± 0.696
1.318SerPro: 1.318 ± 1.334
1.757SerGln: 1.757 ± 1.022
3.514SerArg: 3.514 ± 0.59
4.173SerSer: 4.173 ± 0.771
3.514SerThr: 3.514 ± 0.733
7.907SerVal: 7.907 ± 1.003
0.0SerTrp: 0.0 ± 0.0
2.196SerTyr: 2.196 ± 0.697
0.0SerXaa: 0.0 ± 0.0
Thr
4.612ThrAla: 4.612 ± 0.583
0.0ThrCys: 0.0 ± 0.0
3.514ThrAsp: 3.514 ± 0.855
5.711ThrGlu: 5.711 ± 0.888
3.295ThrPhe: 3.295 ± 0.81
1.757ThrGly: 1.757 ± 0.501
1.757ThrHis: 1.757 ± 0.678
1.318ThrIle: 1.318 ± 0.538
3.734ThrLys: 3.734 ± 0.831
3.734ThrLeu: 3.734 ± 0.749
1.098ThrMet: 1.098 ± 0.448
2.196ThrAsn: 2.196 ± 0.727
2.855ThrPro: 2.855 ± 0.389
3.514ThrGln: 3.514 ± 1.214
3.734ThrArg: 3.734 ± 0.746
3.295ThrSer: 3.295 ± 0.785
3.953ThrThr: 3.953 ± 1.28
7.248ThrVal: 7.248 ± 1.023
0.659ThrTrp: 0.659 ± 0.269
1.537ThrTyr: 1.537 ± 0.455
0.0ThrXaa: 0.0 ± 0.0
Val
3.734ValAla: 3.734 ± 0.489
0.879ValCys: 0.879 ± 0.39
5.491ValAsp: 5.491 ± 1.655
7.687ValGlu: 7.687 ± 0.878
4.173ValPhe: 4.173 ± 1.35
3.295ValGly: 3.295 ± 0.662
1.537ValHis: 1.537 ± 0.435
3.295ValIle: 3.295 ± 0.739
4.832ValLys: 4.832 ± 0.668
7.687ValLeu: 7.687 ± 0.943
2.636ValMet: 2.636 ± 0.861
3.514ValAsn: 3.514 ± 0.792
5.93ValPro: 5.93 ± 1.226
2.196ValGln: 2.196 ± 0.698
5.491ValArg: 5.491 ± 0.724
5.052ValSer: 5.052 ± 1.531
4.612ValThr: 4.612 ± 0.488
8.785ValVal: 8.785 ± 1.137
1.098ValTrp: 1.098 ± 0.421
4.173ValTyr: 4.173 ± 0.749
0.0ValXaa: 0.0 ± 0.0
Trp
0.439TrpAla: 0.439 ± 0.169
0.439TrpCys: 0.439 ± 0.169
0.439TrpAsp: 0.439 ± 0.169
1.537TrpGlu: 1.537 ± 0.438
0.0TrpPhe: 0.0 ± 0.0
0.439TrpGly: 0.439 ± 0.169
0.22TrpHis: 0.22 ± 0.4
0.879TrpIle: 0.879 ± 0.337
0.879TrpLys: 0.879 ± 0.232
1.537TrpLeu: 1.537 ± 1.145
0.22TrpMet: 0.22 ± 0.141
0.22TrpAsn: 0.22 ± 0.156
0.0TrpPro: 0.0 ± 0.0
0.659TrpGln: 0.659 ± 0.396
0.659TrpArg: 0.659 ± 0.385
0.22TrpSer: 0.22 ± 0.156
0.659TrpThr: 0.659 ± 0.343
0.439TrpVal: 0.439 ± 0.169
0.22TrpTrp: 0.22 ± 0.156
0.879TrpTyr: 0.879 ± 0.337
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.196TyrAla: 2.196 ± 0.505
1.318TyrCys: 1.318 ± 0.506
2.196TyrAsp: 2.196 ± 0.619
0.879TyrGlu: 0.879 ± 0.406
1.098TyrPhe: 1.098 ± 0.398
1.537TyrGly: 1.537 ± 0.582
0.22TyrHis: 0.22 ± 0.248
0.439TyrIle: 0.439 ± 0.169
1.977TyrLys: 1.977 ± 0.657
4.173TyrLeu: 4.173 ± 1.17
0.439TyrMet: 0.439 ± 0.169
2.636TyrAsn: 2.636 ± 1.306
1.977TyrPro: 1.977 ± 0.549
1.098TyrGln: 1.098 ± 0.421
1.757TyrArg: 1.757 ± 0.622
0.879TyrSer: 0.879 ± 0.727
3.514TyrThr: 3.514 ± 0.871
3.734TyrVal: 3.734 ± 0.694
0.22TyrTrp: 0.22 ± 0.4
1.318TyrTyr: 1.318 ± 0.506
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.439XaaArg: 0.439 ± 0.239
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4554 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski