Amino acid dipepetide frequency for Loveridges garter snake virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.277AlaAla: 6.277 ± 1.492
0.991AlaCys: 0.991 ± 0.439
2.643AlaAsp: 2.643 ± 0.831
2.313AlaGlu: 2.313 ± 1.005
3.304AlaPhe: 3.304 ± 1.146
3.304AlaGly: 3.304 ± 1.72
0.991AlaHis: 0.991 ± 0.541
4.625AlaIle: 4.625 ± 1.484
2.313AlaLys: 2.313 ± 0.947
10.241AlaLeu: 10.241 ± 2.694
1.321AlaMet: 1.321 ± 0.766
0.661AlaAsn: 0.661 ± 0.419
3.634AlaPro: 3.634 ± 1.008
1.652AlaGln: 1.652 ± 1.292
2.643AlaArg: 2.643 ± 1.445
4.625AlaSer: 4.625 ± 1.67
4.955AlaThr: 4.955 ± 2.078
3.634AlaVal: 3.634 ± 0.923
0.991AlaTrp: 0.991 ± 0.785
0.991AlaTyr: 0.991 ± 0.574
0.0AlaXaa: 0.0 ± 0.0
Cys
0.33CysAla: 0.33 ± 0.191
0.991CysCys: 0.991 ± 0.432
0.661CysAsp: 0.661 ± 0.365
0.991CysGlu: 0.991 ± 0.785
0.661CysPhe: 0.661 ± 0.419
0.33CysGly: 0.33 ± 0.191
0.991CysHis: 0.991 ± 0.382
1.321CysIle: 1.321 ± 0.729
0.33CysLys: 0.33 ± 0.191
3.304CysLeu: 3.304 ± 1.54
0.661CysMet: 0.661 ± 0.419
1.321CysAsn: 1.321 ± 1.219
1.652CysPro: 1.652 ± 0.55
0.0CysGln: 0.0 ± 0.0
0.661CysArg: 0.661 ± 0.365
2.313CysSer: 2.313 ± 2.025
0.991CysThr: 0.991 ± 0.785
0.661CysVal: 0.661 ± 0.383
0.661CysTrp: 0.661 ± 0.383
0.661CysTyr: 0.661 ± 0.365
0.0CysXaa: 0.0 ± 0.0
Asp
3.634AspAla: 3.634 ± 0.96
0.991AspCys: 0.991 ± 0.785
1.321AspAsp: 1.321 ± 0.652
1.321AspGlu: 1.321 ± 1.165
2.643AspPhe: 2.643 ± 1.844
2.313AspGly: 2.313 ± 0.92
0.33AspHis: 0.33 ± 0.48
5.616AspIle: 5.616 ± 0.39
4.295AspLys: 4.295 ± 2.11
3.964AspLeu: 3.964 ± 0.995
1.982AspMet: 1.982 ± 0.829
1.982AspAsn: 1.982 ± 0.915
4.625AspPro: 4.625 ± 1.568
1.321AspGln: 1.321 ± 0.566
1.652AspArg: 1.652 ± 0.639
4.295AspSer: 4.295 ± 1.358
2.313AspThr: 2.313 ± 0.848
2.313AspVal: 2.313 ± 0.91
0.661AspTrp: 0.661 ± 0.419
2.643AspTyr: 2.643 ± 0.88
0.0AspXaa: 0.0 ± 0.0
Glu
3.964GluAla: 3.964 ± 0.835
0.33GluCys: 0.33 ± 0.191
2.643GluAsp: 2.643 ± 0.5
6.938GluGlu: 6.938 ± 2.778
2.643GluPhe: 2.643 ± 1.052
0.991GluGly: 0.991 ± 0.574
0.991GluHis: 0.991 ± 0.574
5.946GluIle: 5.946 ± 0.539
2.313GluLys: 2.313 ± 1.112
6.277GluLeu: 6.277 ± 0.951
1.321GluMet: 1.321 ± 0.729
1.321GluAsn: 1.321 ± 1.104
2.313GluPro: 2.313 ± 0.524
2.643GluGln: 2.643 ± 1.223
2.973GluArg: 2.973 ± 0.839
5.286GluSer: 5.286 ± 1.504
3.634GluThr: 3.634 ± 1.606
3.634GluVal: 3.634 ± 0.935
0.33GluTrp: 0.33 ± 0.191
0.991GluTyr: 0.991 ± 0.791
0.0GluXaa: 0.0 ± 0.0
Phe
0.991PheAla: 0.991 ± 0.439
0.661PheCys: 0.661 ± 0.383
2.313PheAsp: 2.313 ± 0.722
1.982PheGlu: 1.982 ± 0.653
1.982PhePhe: 1.982 ± 0.79
1.982PheGly: 1.982 ± 1.047
0.991PheHis: 0.991 ± 0.574
1.652PheIle: 1.652 ± 0.957
0.991PheLys: 0.991 ± 0.88
5.946PheLeu: 5.946 ± 0.915
0.33PheMet: 0.33 ± 0.674
2.643PheAsn: 2.643 ± 0.565
1.982PhePro: 1.982 ± 0.996
1.321PheGln: 1.321 ± 0.533
3.634PheArg: 3.634 ± 1.041
1.982PheSer: 1.982 ± 0.66
1.652PheThr: 1.652 ± 0.626
2.643PheVal: 2.643 ± 1.246
0.33PheTrp: 0.33 ± 0.191
0.991PheTyr: 0.991 ± 0.88
0.0PheXaa: 0.0 ± 0.0
Gly
2.973GlyAla: 2.973 ± 1.365
1.652GlyCys: 1.652 ± 0.957
3.964GlyAsp: 3.964 ± 1.126
2.313GlyGlu: 2.313 ± 0.998
1.321GlyPhe: 1.321 ± 0.482
3.304GlyGly: 3.304 ± 0.772
1.321GlyHis: 1.321 ± 0.593
2.973GlyIle: 2.973 ± 1.506
2.973GlyLys: 2.973 ± 0.972
6.938GlyLeu: 6.938 ± 1.514
1.652GlyMet: 1.652 ± 0.722
1.321GlyAsn: 1.321 ± 0.639
3.964GlyPro: 3.964 ± 1.676
1.982GlyGln: 1.982 ± 1.257
2.973GlyArg: 2.973 ± 1.368
6.607GlySer: 6.607 ± 3.157
2.313GlyThr: 2.313 ± 0.596
2.973GlyVal: 2.973 ± 0.722
1.321GlyTrp: 1.321 ± 0.965
1.982GlyTyr: 1.982 ± 0.798
0.0GlyXaa: 0.0 ± 0.0
His
1.321HisAla: 1.321 ± 0.593
0.661HisCys: 0.661 ± 0.419
0.661HisAsp: 0.661 ± 0.365
0.661HisGlu: 0.661 ± 0.792
1.652HisPhe: 1.652 ± 0.67
1.321HisGly: 1.321 ± 0.796
0.661HisHis: 0.661 ± 0.383
0.661HisIle: 0.661 ± 0.365
1.982HisLys: 1.982 ± 0.764
3.304HisLeu: 3.304 ± 0.989
0.991HisMet: 0.991 ± 0.791
0.33HisAsn: 0.33 ± 0.191
0.33HisPro: 0.33 ± 0.48
0.661HisGln: 0.661 ± 0.961
1.982HisArg: 1.982 ± 0.653
1.321HisSer: 1.321 ± 0.728
0.991HisThr: 0.991 ± 0.382
0.33HisVal: 0.33 ± 0.191
0.661HisTrp: 0.661 ± 0.383
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.313IleAla: 2.313 ± 0.999
1.982IleCys: 1.982 ± 1.094
5.946IleAsp: 5.946 ± 1.282
2.313IleGlu: 2.313 ± 0.757
1.652IlePhe: 1.652 ± 0.626
3.964IleGly: 3.964 ± 1.728
0.661IleHis: 0.661 ± 0.383
5.946IleIle: 5.946 ± 1.801
4.295IleLys: 4.295 ± 1.695
5.946IleLeu: 5.946 ± 1.858
1.982IleMet: 1.982 ± 0.864
4.955IleAsn: 4.955 ± 1.495
3.304IlePro: 3.304 ± 0.62
2.313IleGln: 2.313 ± 0.767
4.955IleArg: 4.955 ± 0.978
5.946IleSer: 5.946 ± 1.725
3.304IleThr: 3.304 ± 1.251
4.295IleVal: 4.295 ± 1.022
0.661IleTrp: 0.661 ± 0.365
2.973IleTyr: 2.973 ± 1.201
0.0IleXaa: 0.0 ± 0.0
Lys
2.973LysAla: 2.973 ± 1.127
0.33LysCys: 0.33 ± 0.191
2.313LysAsp: 2.313 ± 1.891
3.964LysGlu: 3.964 ± 1.705
1.652LysPhe: 1.652 ± 0.483
2.643LysGly: 2.643 ± 0.92
1.652LysHis: 1.652 ± 1.32
3.304LysIle: 3.304 ± 0.844
2.313LysLys: 2.313 ± 0.767
6.607LysLeu: 6.607 ± 1.604
2.973LysMet: 2.973 ± 0.867
0.991LysAsn: 0.991 ± 0.439
2.643LysPro: 2.643 ± 0.565
1.652LysGln: 1.652 ± 0.733
5.286LysArg: 5.286 ± 1.931
4.625LysSer: 4.625 ± 1.217
2.973LysThr: 2.973 ± 0.494
2.313LysVal: 2.313 ± 0.864
1.321LysTrp: 1.321 ± 0.729
0.991LysTyr: 0.991 ± 0.432
0.0LysXaa: 0.0 ± 0.0
Leu
8.92LeuAla: 8.92 ± 2.009
1.652LeuCys: 1.652 ± 1.171
7.598LeuAsp: 7.598 ± 2.367
6.938LeuGlu: 6.938 ± 1.599
2.313LeuPhe: 2.313 ± 0.699
6.938LeuGly: 6.938 ± 1.45
0.991LeuHis: 0.991 ± 0.914
8.589LeuIle: 8.589 ± 1.224
5.286LeuLys: 5.286 ± 0.957
8.92LeuLeu: 8.92 ± 1.384
2.313LeuMet: 2.313 ± 1.135
4.955LeuAsn: 4.955 ± 1.469
5.946LeuPro: 5.946 ± 0.959
2.973LeuGln: 2.973 ± 0.617
5.616LeuArg: 5.616 ± 0.968
6.938LeuSer: 6.938 ± 1.14
7.268LeuThr: 7.268 ± 1.618
8.92LeuVal: 8.92 ± 1.217
0.33LeuTrp: 0.33 ± 0.191
4.295LeuTyr: 4.295 ± 0.909
0.0LeuXaa: 0.0 ± 0.0
Met
2.313MetAla: 2.313 ± 1.884
0.991MetCys: 0.991 ± 0.382
1.982MetAsp: 1.982 ± 1.189
0.991MetGlu: 0.991 ± 0.439
0.33MetPhe: 0.33 ± 0.48
1.652MetGly: 1.652 ± 0.763
0.0MetHis: 0.0 ± 0.0
1.982MetIle: 1.982 ± 0.915
1.321MetLys: 1.321 ± 1.016
1.982MetLeu: 1.982 ± 0.78
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.652MetPro: 1.652 ± 0.67
0.661MetGln: 0.661 ± 0.365
0.991MetArg: 0.991 ± 0.439
3.304MetSer: 3.304 ± 0.972
2.643MetThr: 2.643 ± 0.763
0.661MetVal: 0.661 ± 0.383
0.0MetTrp: 0.0 ± 0.0
1.982MetTyr: 1.982 ± 0.78
0.0MetXaa: 0.0 ± 0.0
Asn
2.973AsnAla: 2.973 ± 0.8
0.661AsnCys: 0.661 ± 0.365
1.652AsnAsp: 1.652 ± 0.722
1.652AsnGlu: 1.652 ± 0.626
0.661AsnPhe: 0.661 ± 0.6
0.661AsnGly: 0.661 ± 0.365
1.652AsnHis: 1.652 ± 0.722
2.313AsnIle: 2.313 ± 0.746
1.652AsnLys: 1.652 ± 0.612
4.625AsnLeu: 4.625 ± 0.711
0.33AsnMet: 0.33 ± 0.545
1.652AsnAsn: 1.652 ± 1.656
2.643AsnPro: 2.643 ± 0.5
3.304AsnGln: 3.304 ± 1.204
2.313AsnArg: 2.313 ± 0.822
2.643AsnSer: 2.643 ± 0.615
1.321AsnThr: 1.321 ± 0.729
2.313AsnVal: 2.313 ± 1.132
0.991AsnTrp: 0.991 ± 0.382
0.661AsnTyr: 0.661 ± 0.6
0.0AsnXaa: 0.0 ± 0.0
Pro
3.304ProAla: 3.304 ± 0.784
0.991ProCys: 0.991 ± 0.574
2.643ProAsp: 2.643 ± 1.304
4.625ProGlu: 4.625 ± 0.707
1.982ProPhe: 1.982 ± 0.829
4.295ProGly: 4.295 ± 1.464
0.661ProHis: 0.661 ± 0.961
3.304ProIle: 3.304 ± 0.748
2.313ProLys: 2.313 ± 0.643
5.946ProLeu: 5.946 ± 1.618
1.652ProMet: 1.652 ± 0.696
1.321ProAsn: 1.321 ± 0.723
3.634ProPro: 3.634 ± 0.756
0.991ProGln: 0.991 ± 1.036
2.313ProArg: 2.313 ± 0.826
3.964ProSer: 3.964 ± 0.797
2.643ProThr: 2.643 ± 1.179
2.973ProVal: 2.973 ± 0.901
0.991ProTrp: 0.991 ± 0.574
1.652ProTyr: 1.652 ± 1.142
0.0ProXaa: 0.0 ± 0.0
Gln
1.321GlnAla: 1.321 ± 0.328
0.991GlnCys: 0.991 ± 0.432
0.991GlnAsp: 0.991 ± 0.718
1.982GlnGlu: 1.982 ± 1.165
1.321GlnPhe: 1.321 ± 0.593
1.982GlnGly: 1.982 ± 1.149
0.661GlnHis: 0.661 ± 0.6
1.321GlnIle: 1.321 ± 0.723
1.982GlnLys: 1.982 ± 0.829
5.616GlnLeu: 5.616 ± 2.119
1.652GlnMet: 1.652 ± 0.899
0.661GlnAsn: 0.661 ± 0.365
1.982GlnPro: 1.982 ± 0.653
0.33GlnGln: 0.33 ± 0.191
0.661GlnArg: 0.661 ± 0.592
5.286GlnSer: 5.286 ± 0.603
2.643GlnThr: 2.643 ± 0.615
1.652GlnVal: 1.652 ± 0.483
0.0GlnTrp: 0.0 ± 0.0
0.661GlnTyr: 0.661 ± 0.961
0.0GlnXaa: 0.0 ± 0.0
Arg
4.295ArgAla: 4.295 ± 1.397
0.991ArgCys: 0.991 ± 0.785
3.304ArgAsp: 3.304 ± 0.51
4.295ArgGlu: 4.295 ± 1.464
2.643ArgPhe: 2.643 ± 1.176
2.313ArgGly: 2.313 ± 0.726
0.661ArgHis: 0.661 ± 0.419
2.313ArgIle: 2.313 ± 0.999
5.286ArgLys: 5.286 ± 1.911
6.938ArgLeu: 6.938 ± 2.337
0.33ArgMet: 0.33 ± 0.191
1.321ArgAsn: 1.321 ± 1.199
2.643ArgPro: 2.643 ± 0.724
2.643ArgGln: 2.643 ± 1.279
5.286ArgArg: 5.286 ± 2.481
3.964ArgSer: 3.964 ± 1.374
1.982ArgThr: 1.982 ± 0.983
2.973ArgVal: 2.973 ± 0.986
0.661ArgTrp: 0.661 ± 0.365
1.982ArgTyr: 1.982 ± 0.411
0.0ArgXaa: 0.0 ± 0.0
Ser
4.955SerAla: 4.955 ± 1.646
1.982SerCys: 1.982 ± 0.768
2.643SerAsp: 2.643 ± 0.549
3.964SerGlu: 3.964 ± 1.098
3.304SerPhe: 3.304 ± 1.278
5.286SerGly: 5.286 ± 2.853
2.313SerHis: 2.313 ± 0.854
5.286SerIle: 5.286 ± 0.779
4.625SerLys: 4.625 ± 1.123
7.598SerLeu: 7.598 ± 1.264
2.313SerMet: 2.313 ± 0.826
3.634SerAsn: 3.634 ± 1.076
2.973SerPro: 2.973 ± 0.95
1.982SerGln: 1.982 ± 1.31
5.286SerArg: 5.286 ± 1.855
8.589SerSer: 8.589 ± 1.973
6.938SerThr: 6.938 ± 2.103
7.268SerVal: 7.268 ± 2.276
1.982SerTrp: 1.982 ± 0.553
5.286SerTyr: 5.286 ± 2.981
0.0SerXaa: 0.0 ± 0.0
Thr
4.625ThrAla: 4.625 ± 2.551
0.991ThrCys: 0.991 ± 0.785
2.643ThrAsp: 2.643 ± 0.565
3.634ThrGlu: 3.634 ± 0.854
1.321ThrPhe: 1.321 ± 0.729
5.286ThrGly: 5.286 ± 0.687
1.652ThrHis: 1.652 ± 0.626
5.286ThrIle: 5.286 ± 1.265
1.982ThrLys: 1.982 ± 0.411
4.955ThrLeu: 4.955 ± 1.517
1.982ThrMet: 1.982 ± 0.829
2.643ThrAsn: 2.643 ± 1.15
1.982ThrPro: 1.982 ± 0.553
2.313ThrGln: 2.313 ± 0.38
2.973ThrArg: 2.973 ± 1.072
3.964ThrSer: 3.964 ± 1.06
3.634ThrThr: 3.634 ± 1.142
4.625ThrVal: 4.625 ± 1.793
0.991ThrTrp: 0.991 ± 0.574
2.643ThrTyr: 2.643 ± 0.565
0.0ThrXaa: 0.0 ± 0.0
Val
2.643ValAla: 2.643 ± 1.067
0.33ValCys: 0.33 ± 0.191
2.973ValAsp: 2.973 ± 1.185
4.625ValGlu: 4.625 ± 1.285
2.313ValPhe: 2.313 ± 0.767
5.286ValGly: 5.286 ± 1.619
1.321ValHis: 1.321 ± 0.965
4.955ValIle: 4.955 ± 1.326
3.964ValLys: 3.964 ± 1.069
2.643ValLeu: 2.643 ± 0.59
0.33ValMet: 0.33 ± 0.191
2.973ValAsn: 2.973 ± 1.546
1.321ValPro: 1.321 ± 0.728
3.634ValGln: 3.634 ± 1.303
3.304ValArg: 3.304 ± 1.134
7.598ValSer: 7.598 ± 2.578
5.286ValThr: 5.286 ± 1.246
6.277ValVal: 6.277 ± 2.188
0.0ValTrp: 0.0 ± 0.0
1.652ValTyr: 1.652 ± 0.713
0.0ValXaa: 0.0 ± 0.0
Trp
0.33TrpAla: 0.33 ± 0.44
0.33TrpCys: 0.33 ± 0.191
0.0TrpAsp: 0.0 ± 0.0
0.661TrpGlu: 0.661 ± 0.365
0.991TrpPhe: 0.991 ± 0.439
0.991TrpGly: 0.991 ± 0.382
0.661TrpHis: 0.661 ± 0.383
0.991TrpIle: 0.991 ± 0.382
0.661TrpLys: 0.661 ± 0.792
1.982TrpLeu: 1.982 ± 0.79
0.0TrpMet: 0.0 ± 0.0
0.661TrpAsn: 0.661 ± 0.365
0.661TrpPro: 0.661 ± 0.383
0.33TrpGln: 0.33 ± 0.44
0.33TrpArg: 0.33 ± 0.191
1.652TrpSer: 1.652 ± 0.319
0.33TrpThr: 0.33 ± 0.191
1.652TrpVal: 1.652 ± 0.639
0.0TrpTrp: 0.0 ± 0.0
0.661TrpTyr: 0.661 ± 0.365
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.652TyrAla: 1.652 ± 0.728
0.991TyrCys: 0.991 ± 0.785
1.321TyrAsp: 1.321 ± 0.54
1.321TyrGlu: 1.321 ± 0.533
2.643TyrPhe: 2.643 ± 1.075
1.982TyrGly: 1.982 ± 0.653
1.321TyrHis: 1.321 ± 0.328
1.321TyrIle: 1.321 ± 0.593
2.643TyrLys: 2.643 ± 1.021
3.964TyrLeu: 3.964 ± 1.506
0.991TyrMet: 0.991 ± 0.785
1.321TyrAsn: 1.321 ± 0.328
2.313TyrPro: 2.313 ± 0.38
0.991TyrGln: 0.991 ± 0.382
0.991TyrArg: 0.991 ± 0.672
3.304TyrSer: 3.304 ± 1.099
2.313TyrThr: 2.313 ± 0.525
1.321TyrVal: 1.321 ± 0.593
0.991TyrTrp: 0.991 ± 0.432
1.321TyrTyr: 1.321 ± 0.482
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3028 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski