Amino acid dipepetide frequency for Capybara microvirus Cap1_SP_90

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.603AlaAla: 4.603 ± 3.182
1.151AlaCys: 1.151 ± 0.439
3.452AlaAsp: 3.452 ± 1.568
4.028AlaGlu: 4.028 ± 1.82
2.301AlaPhe: 2.301 ± 0.701
7.48AlaGly: 7.48 ± 2.835
2.877AlaHis: 2.877 ± 1.305
2.301AlaIle: 2.301 ± 0.988
2.877AlaLys: 2.877 ± 0.896
5.178AlaLeu: 5.178 ± 2.079
1.726AlaMet: 1.726 ± 1.681
4.028AlaAsn: 4.028 ± 2.48
1.726AlaPro: 1.726 ± 1.225
4.028AlaGln: 4.028 ± 0.999
1.151AlaArg: 1.151 ± 0.494
5.178AlaSer: 5.178 ± 2.076
3.452AlaThr: 3.452 ± 0.885
3.452AlaVal: 3.452 ± 0.958
0.0AlaTrp: 0.0 ± 0.0
2.877AlaTyr: 2.877 ± 1.157
0.0AlaXaa: 0.0 ± 0.0
Cys
0.575CysAla: 0.575 ± 0.542
0.0CysCys: 0.0 ± 0.0
0.575CysAsp: 0.575 ± 0.542
1.726CysGlu: 1.726 ± 0.898
2.301CysPhe: 2.301 ± 2.169
1.151CysGly: 1.151 ± 0.439
0.0CysHis: 0.0 ± 0.0
1.151CysIle: 1.151 ± 0.439
1.151CysLys: 1.151 ± 0.439
0.575CysLeu: 0.575 ± 0.542
0.0CysMet: 0.0 ± 0.0
0.575CysAsn: 0.575 ± 0.408
1.151CysPro: 1.151 ± 0.857
0.0CysGln: 0.0 ± 0.0
1.151CysArg: 1.151 ± 0.439
1.726CysSer: 1.726 ± 1.212
1.726CysThr: 1.726 ± 1.225
0.0CysVal: 0.0 ± 0.0
0.575CysTrp: 0.575 ± 0.542
1.151CysTyr: 1.151 ± 1.085
0.0CysXaa: 0.0 ± 0.0
Asp
6.329AspAla: 6.329 ± 1.875
0.575AspCys: 0.575 ± 0.542
4.603AspAsp: 4.603 ± 2.048
1.726AspGlu: 1.726 ± 0.975
1.726AspPhe: 1.726 ± 1.048
1.726AspGly: 1.726 ± 0.978
0.0AspHis: 0.0 ± 0.0
5.178AspIle: 5.178 ± 1.578
1.726AspLys: 1.726 ± 0.271
8.631AspLeu: 8.631 ± 1.407
1.726AspMet: 1.726 ± 0.912
2.877AspAsn: 2.877 ± 1.182
2.877AspPro: 2.877 ± 1.427
2.877AspGln: 2.877 ± 1.311
4.028AspArg: 4.028 ± 1.66
2.877AspSer: 2.877 ± 0.876
4.603AspThr: 4.603 ± 2.103
4.028AspVal: 4.028 ± 1.448
1.151AspTrp: 1.151 ± 0.642
2.877AspTyr: 2.877 ± 0.467
0.0AspXaa: 0.0 ± 0.0
Glu
3.452GluAla: 3.452 ± 1.677
2.301GluCys: 2.301 ± 1.417
2.301GluAsp: 2.301 ± 0.701
3.452GluGlu: 3.452 ± 0.885
1.726GluPhe: 1.726 ± 1.048
1.151GluGly: 1.151 ± 0.439
1.151GluHis: 1.151 ± 0.439
2.877GluIle: 2.877 ± 1.44
5.178GluLys: 5.178 ± 3.158
4.603GluLeu: 4.603 ± 0.992
2.301GluMet: 2.301 ± 0.995
1.726GluAsn: 1.726 ± 0.898
1.151GluPro: 1.151 ± 0.817
0.575GluGln: 0.575 ± 0.542
2.301GluArg: 2.301 ± 0.717
4.603GluSer: 4.603 ± 1.52
1.151GluThr: 1.151 ± 0.817
3.452GluVal: 3.452 ± 0.737
0.575GluTrp: 0.575 ± 0.56
4.028GluTyr: 4.028 ± 0.344
0.0GluXaa: 0.0 ± 0.0
Phe
4.028PheAla: 4.028 ± 0.999
0.0PheCys: 0.0 ± 0.0
4.028PheAsp: 4.028 ± 1.048
1.726PheGlu: 1.726 ± 0.271
1.726PhePhe: 1.726 ± 0.898
2.877PheGly: 2.877 ± 1.033
0.575PheHis: 0.575 ± 0.408
1.726PheIle: 1.726 ± 0.652
2.877PheLys: 2.877 ± 1.949
2.877PheLeu: 2.877 ± 0.631
0.0PheMet: 0.0 ± 0.0
3.452PheAsn: 3.452 ± 1.767
3.452PhePro: 3.452 ± 0.958
1.726PheGln: 1.726 ± 0.696
5.754PheArg: 5.754 ± 0.71
2.877PheSer: 2.877 ± 0.896
3.452PheThr: 3.452 ± 1.796
1.726PheVal: 1.726 ± 0.652
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.028GlyAla: 4.028 ± 1.048
0.575GlyCys: 0.575 ± 0.766
4.603GlyAsp: 4.603 ± 1.135
2.877GlyGlu: 2.877 ± 1.375
4.603GlyPhe: 4.603 ± 1.755
1.151GlyGly: 1.151 ± 0.439
0.575GlyHis: 0.575 ± 0.542
4.028GlyIle: 4.028 ± 0.526
2.877GlyLys: 2.877 ± 1.305
5.754GlyLeu: 5.754 ± 1.746
0.575GlyMet: 0.575 ± 0.408
1.151GlyAsn: 1.151 ± 0.817
0.0GlyPro: 0.0 ± 0.0
1.151GlyGln: 1.151 ± 0.494
1.726GlyArg: 1.726 ± 0.652
8.055GlySer: 8.055 ± 2.096
2.877GlyThr: 2.877 ± 1.632
5.754GlyVal: 5.754 ± 1.262
0.0GlyTrp: 0.0 ± 0.0
5.754GlyTyr: 5.754 ± 0.71
0.0GlyXaa: 0.0 ± 0.0
His
0.575HisAla: 0.575 ± 0.542
0.575HisCys: 0.575 ± 0.542
1.726HisAsp: 1.726 ± 0.898
0.575HisGlu: 0.575 ± 0.408
1.151HisPhe: 1.151 ± 1.085
0.575HisGly: 0.575 ± 0.408
0.0HisHis: 0.0 ± 0.0
0.575HisIle: 0.575 ± 0.408
1.726HisLys: 1.726 ± 0.898
2.301HisLeu: 2.301 ± 1.417
0.0HisMet: 0.0 ± 0.0
0.575HisAsn: 0.575 ± 0.408
0.0HisPro: 0.0 ± 0.0
1.726HisGln: 1.726 ± 0.652
0.575HisArg: 0.575 ± 0.542
2.301HisSer: 2.301 ± 0.878
1.726HisThr: 1.726 ± 0.652
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.151HisTyr: 1.151 ± 1.085
0.0HisXaa: 0.0 ± 0.0
Ile
2.877IleAla: 2.877 ± 1.949
2.301IleCys: 2.301 ± 0.878
5.178IleAsp: 5.178 ± 2.137
2.877IleGlu: 2.877 ± 1.72
2.301IlePhe: 2.301 ± 1.051
1.726IleGly: 1.726 ± 0.713
0.0IleHis: 0.0 ± 0.0
2.301IleIle: 2.301 ± 1.282
5.178IleLys: 5.178 ± 3.48
4.028IleLeu: 4.028 ± 0.927
1.151IleMet: 1.151 ± 0.494
3.452IleAsn: 3.452 ± 1.677
4.028IlePro: 4.028 ± 1.434
2.301IleGln: 2.301 ± 0.263
1.726IleArg: 1.726 ± 1.076
5.754IleSer: 5.754 ± 2.146
2.301IleThr: 2.301 ± 1.417
2.877IleVal: 2.877 ± 0.896
0.0IleTrp: 0.0 ± 0.0
2.301IleTyr: 2.301 ± 0.878
0.0IleXaa: 0.0 ± 0.0
Lys
4.028LysAla: 4.028 ± 0.344
1.726LysCys: 1.726 ± 1.627
4.028LysAsp: 4.028 ± 1.605
4.603LysGlu: 4.603 ± 2.836
4.028LysPhe: 4.028 ± 0.526
2.301LysGly: 2.301 ± 0.878
1.151LysHis: 1.151 ± 1.085
1.726LysIle: 1.726 ± 0.652
5.754LysLys: 5.754 ± 2.447
4.028LysLeu: 4.028 ± 1.535
2.877LysMet: 2.877 ± 1.069
2.877LysAsn: 2.877 ± 1.65
2.301LysPro: 2.301 ± 0.878
2.877LysGln: 2.877 ± 1.157
1.151LysArg: 1.151 ± 0.494
5.754LysSer: 5.754 ± 1.105
2.301LysThr: 2.301 ± 1.377
3.452LysVal: 3.452 ± 1.27
0.575LysTrp: 0.575 ± 0.408
4.028LysTyr: 4.028 ± 2.165
0.0LysXaa: 0.0 ± 0.0
Leu
5.754LeuAla: 5.754 ± 1.669
1.726LeuCys: 1.726 ± 0.652
4.028LeuAsp: 4.028 ± 0.865
4.603LeuGlu: 4.603 ± 1.951
2.301LeuPhe: 2.301 ± 0.263
7.48LeuGly: 7.48 ± 2.05
2.301LeuHis: 2.301 ± 0.878
4.028LeuIle: 4.028 ± 2.09
5.754LeuLys: 5.754 ± 0.365
5.754LeuLeu: 5.754 ± 0.873
1.726LeuMet: 1.726 ± 0.652
4.028LeuAsn: 4.028 ± 2.091
6.329LeuPro: 6.329 ± 1.543
3.452LeuGln: 3.452 ± 0.528
2.301LeuArg: 2.301 ± 0.988
6.329LeuSer: 6.329 ± 1.81
8.055LeuThr: 8.055 ± 2.308
4.028LeuVal: 4.028 ± 1.82
0.575LeuTrp: 0.575 ± 0.408
2.877LeuTyr: 2.877 ± 0.584
0.0LeuXaa: 0.0 ± 0.0
Met
2.301MetAla: 2.301 ± 0.988
0.575MetCys: 0.575 ± 0.542
0.575MetAsp: 0.575 ± 0.408
0.575MetGlu: 0.575 ± 0.56
1.726MetPhe: 1.726 ± 0.978
0.575MetGly: 0.575 ± 0.408
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.151MetLys: 1.151 ± 0.494
1.726MetLeu: 1.726 ± 0.652
1.151MetMet: 1.151 ± 0.642
1.726MetAsn: 1.726 ± 0.652
2.301MetPro: 2.301 ± 1.511
0.0MetGln: 0.0 ± 0.0
2.301MetArg: 2.301 ± 0.763
4.028MetSer: 4.028 ± 1.664
0.575MetThr: 0.575 ± 0.766
0.575MetVal: 0.575 ± 0.542
0.0MetTrp: 0.0 ± 0.0
1.726MetTyr: 1.726 ± 1.225
0.0MetXaa: 0.0 ± 0.0
Asn
4.028AsnAla: 4.028 ± 3.171
0.0AsnCys: 0.0 ± 0.0
3.452AsnAsp: 3.452 ± 1.27
2.877AsnGlu: 2.877 ± 0.601
1.726AsnPhe: 1.726 ± 1.225
2.877AsnGly: 2.877 ± 1.033
1.726AsnHis: 1.726 ± 0.898
2.877AsnIle: 2.877 ± 1.375
4.028AsnLys: 4.028 ± 0.977
4.028AsnLeu: 4.028 ± 1.712
1.726AsnMet: 1.726 ± 0.975
5.754AsnAsn: 5.754 ± 1.948
5.754AsnPro: 5.754 ± 0.934
0.0AsnGln: 0.0 ± 0.0
1.151AsnArg: 1.151 ± 0.439
5.754AsnSer: 5.754 ± 4.121
5.178AsnThr: 5.178 ± 1.258
4.603AsnVal: 4.603 ± 1.857
1.151AsnTrp: 1.151 ± 0.494
1.726AsnTyr: 1.726 ± 1.225
0.0AsnXaa: 0.0 ± 0.0
Pro
0.575ProAla: 0.575 ± 0.408
0.575ProCys: 0.575 ± 0.542
2.877ProAsp: 2.877 ± 1.033
1.726ProGlu: 1.726 ± 0.975
0.575ProPhe: 0.575 ± 0.542
2.301ProGly: 2.301 ± 0.988
1.151ProHis: 1.151 ± 1.085
4.603ProIle: 4.603 ± 2.179
0.575ProLys: 0.575 ± 0.542
2.877ProLeu: 2.877 ± 1.375
0.0ProMet: 0.0 ± 0.0
2.301ProAsn: 2.301 ± 0.988
0.0ProPro: 0.0 ± 0.0
2.877ProGln: 2.877 ± 1.305
2.877ProArg: 2.877 ± 1.949
5.178ProSer: 5.178 ± 0.712
6.329ProThr: 6.329 ± 1.239
3.452ProVal: 3.452 ± 0.885
0.575ProTrp: 0.575 ± 0.408
3.452ProTyr: 3.452 ± 1.767
0.0ProXaa: 0.0 ± 0.0
Gln
1.151GlnAla: 1.151 ± 1.121
1.726GlnCys: 1.726 ± 0.696
2.877GlnAsp: 2.877 ± 0.631
1.726GlnGlu: 1.726 ± 1.681
4.028GlnPhe: 4.028 ± 1.048
1.726GlnGly: 1.726 ± 1.048
0.0GlnHis: 0.0 ± 0.0
1.726GlnIle: 1.726 ± 0.898
1.726GlnLys: 1.726 ± 0.898
3.452GlnLeu: 3.452 ± 1.817
1.726GlnMet: 1.726 ± 1.242
1.726GlnAsn: 1.726 ± 0.713
1.726GlnPro: 1.726 ± 1.225
3.452GlnGln: 3.452 ± 2.676
1.151GlnArg: 1.151 ± 0.439
3.452GlnSer: 3.452 ± 0.528
0.575GlnThr: 0.575 ± 0.56
2.301GlnVal: 2.301 ± 1.965
0.0GlnTrp: 0.0 ± 0.0
2.877GlnTyr: 2.877 ± 1.033
0.0GlnXaa: 0.0 ± 0.0
Arg
3.452ArgAla: 3.452 ± 1.677
0.575ArgCys: 0.575 ± 0.542
3.452ArgAsp: 3.452 ± 1.114
1.726ArgGlu: 1.726 ± 0.912
4.028ArgPhe: 4.028 ± 1.448
2.877ArgGly: 2.877 ± 0.601
1.151ArgHis: 1.151 ± 0.439
1.151ArgIle: 1.151 ± 0.817
1.726ArgLys: 1.726 ± 0.271
2.301ArgLeu: 2.301 ± 1.634
2.301ArgMet: 2.301 ± 0.774
5.178ArgAsn: 5.178 ± 2.176
1.726ArgPro: 1.726 ± 0.898
2.301ArgGln: 2.301 ± 0.763
1.151ArgArg: 1.151 ± 0.439
2.301ArgSer: 2.301 ± 0.263
1.726ArgThr: 1.726 ± 0.696
2.301ArgVal: 2.301 ± 0.976
0.0ArgTrp: 0.0 ± 0.0
2.877ArgTyr: 2.877 ± 1.033
0.0ArgXaa: 0.0 ± 0.0
Ser
4.603SerAla: 4.603 ± 0.526
0.575SerCys: 0.575 ± 0.542
4.603SerAsp: 4.603 ± 2.179
2.301SerGlu: 2.301 ± 0.263
2.877SerPhe: 2.877 ± 1.427
6.904SerGly: 6.904 ± 2.05
1.726SerHis: 1.726 ± 0.652
4.603SerIle: 4.603 ± 2.804
4.028SerLys: 4.028 ± 1.529
10.932SerLeu: 10.932 ± 2.556
2.301SerMet: 2.301 ± 1.634
5.178SerAsn: 5.178 ± 0.712
3.452SerPro: 3.452 ± 1.321
2.877SerGln: 2.877 ± 2.129
5.178SerArg: 5.178 ± 1.524
6.329SerSer: 6.329 ± 0.549
9.206SerThr: 9.206 ± 1.29
4.028SerVal: 4.028 ± 2.166
1.726SerTrp: 1.726 ± 1.225
2.877SerTyr: 2.877 ± 0.896
0.0SerXaa: 0.0 ± 0.0
Thr
3.452ThrAla: 3.452 ± 1.426
1.151ThrCys: 1.151 ± 0.439
1.726ThrAsp: 1.726 ± 0.652
3.452ThrGlu: 3.452 ± 0.604
2.301ThrPhe: 2.301 ± 1.051
6.904ThrGly: 6.904 ± 2.066
1.151ThrHis: 1.151 ± 0.439
5.754ThrIle: 5.754 ± 1.633
4.028ThrLys: 4.028 ± 0.865
3.452ThrLeu: 3.452 ± 0.737
0.575ThrMet: 0.575 ± 0.408
4.603ThrAsn: 4.603 ± 1.273
1.151ThrPro: 1.151 ± 0.642
3.452ThrGln: 3.452 ± 0.737
1.726ThrArg: 1.726 ± 0.652
5.178ThrSer: 5.178 ± 1.051
4.603ThrThr: 4.603 ± 1.874
5.178ThrVal: 5.178 ± 2.198
0.0ThrTrp: 0.0 ± 0.0
6.904ThrTyr: 6.904 ± 1.302
0.0ThrXaa: 0.0 ± 0.0
Val
5.178ValAla: 5.178 ± 1.531
0.575ValCys: 0.575 ± 0.542
2.877ValAsp: 2.877 ± 0.601
4.603ValGlu: 4.603 ± 1.492
1.726ValPhe: 1.726 ± 0.652
1.726ValGly: 1.726 ± 0.975
1.151ValHis: 1.151 ± 0.817
2.877ValIle: 2.877 ± 0.876
4.028ValLys: 4.028 ± 0.914
5.178ValLeu: 5.178 ± 1.749
0.575ValMet: 0.575 ± 0.56
4.603ValAsn: 4.603 ± 1.003
4.603ValPro: 4.603 ± 0.724
0.575ValGln: 0.575 ± 0.542
2.301ValArg: 2.301 ± 0.701
5.178ValSer: 5.178 ± 0.876
4.028ValThr: 4.028 ± 0.821
2.301ValVal: 2.301 ± 0.263
0.0ValTrp: 0.0 ± 0.0
2.877ValTyr: 2.877 ± 1.417
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.575TrpCys: 0.575 ± 0.408
1.151TrpAsp: 1.151 ± 0.817
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.575TrpGly: 0.575 ± 0.408
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.151TrpLys: 1.151 ± 0.817
0.575TrpLeu: 0.575 ± 0.56
0.0TrpMet: 0.0 ± 0.0
0.575TrpAsn: 0.575 ± 0.542
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.726TrpArg: 1.726 ± 0.713
0.575TrpSer: 0.575 ± 0.56
0.575TrpThr: 0.575 ± 0.542
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.575TrpTyr: 0.575 ± 0.408
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.877TyrAla: 2.877 ± 1.083
0.0TyrCys: 0.0 ± 0.0
4.028TyrAsp: 4.028 ± 0.927
2.877TyrGlu: 2.877 ± 1.033
1.726TyrPhe: 1.726 ± 0.271
4.028TyrGly: 4.028 ± 1.448
1.151TyrHis: 1.151 ± 1.085
5.178TyrIle: 5.178 ± 1.918
4.028TyrLys: 4.028 ± 0.914
5.178TyrLeu: 5.178 ± 0.529
0.575TyrMet: 0.575 ± 0.56
4.028TyrAsn: 4.028 ± 2.31
1.151TyrPro: 1.151 ± 0.439
3.452TyrGln: 3.452 ± 1.817
2.877TyrArg: 2.877 ± 1.65
2.877TyrSer: 2.877 ± 2.042
2.301TyrThr: 2.301 ± 1.051
3.452TyrVal: 3.452 ± 1.247
1.151TyrTrp: 1.151 ± 0.817
2.877TyrTyr: 2.877 ± 1.375
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1739 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski