Amino acid dipepetide frequency for Actinobaculum sp. oral taxon 183 str. F0552

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.25AlaAla: 18.25 ± 0.27	1.285AlaCys: 1.285 ± 0.051	7.821AlaAsp: 7.821 ± 0.121	7.723AlaGlu: 7.723 ± 0.142	3.945AlaPhe: 3.945 ± 0.086	12.925AlaGly: 12.925 ± 0.187	2.341AlaHis: 2.341 ± 0.056	5.142AlaIle: 5.142 ± 0.099	3.531AlaLys: 3.531 ± 0.099	12.004AlaLeu: 12.004 ± 0.158	2.921AlaMet: 2.921 ± 0.071	2.502AlaAsn: 2.502 ± 0.07	5.997AlaPro: 5.997 ± 0.117	3.573AlaGln: 3.573 ± 0.11	9.853AlaArg: 9.853 ± 0.151	8.313AlaSer: 8.313 ± 0.138	6.003AlaThr: 6.003 ± 0.1	11.179AlaVal: 11.179 ± 0.157	1.813AlaTrp: 1.813 ± 0.05	2.724AlaTyr: 2.724 ± 0.073	0.0AlaXaa: 0.0 ± 0.0
Cys	1.127CysAla: 1.127 ± 0.046	0.099CysCys: 0.099 ± 0.013	0.475CysAsp: 0.475 ± 0.03	0.518CysGlu: 0.518 ± 0.029	0.262CysPhe: 0.262 ± 0.017	0.95CysGly: 0.95 ± 0.037	0.168CysHis: 0.168 ± 0.015	0.281CysIle: 0.281 ± 0.022	0.148CysLys: 0.148 ± 0.014	0.885CysLeu: 0.885 ± 0.031	0.144CysMet: 0.144 ± 0.016	0.145CysAsn: 0.145 ± 0.015	0.504CysPro: 0.504 ± 0.028	0.216CysGln: 0.216 ± 0.019	0.63CysArg: 0.63 ± 0.029	0.542CysSer: 0.542 ± 0.028	0.478CysThr: 0.478 ± 0.034	0.682CysVal: 0.682 ± 0.03	0.102CysTrp: 0.102 ± 0.014	0.209CysTyr: 0.209 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.652AspAla: 7.652 ± 0.118	0.419AspCys: 0.419 ± 0.022	3.36AspAsp: 3.36 ± 0.079	3.827AspGlu: 3.827 ± 0.086	1.787AspPhe: 1.787 ± 0.053	6.221AspGly: 6.221 ± 0.098	1.06AspHis: 1.06 ± 0.044	2.338AspIle: 2.338 ± 0.07	1.331AspLys: 1.331 ± 0.055	5.685AspLeu: 5.685 ± 0.107	1.092AspMet: 1.092 ± 0.042	0.932AspAsn: 0.932 ± 0.039	4.044AspPro: 4.044 ± 0.092	1.288AspGln: 1.288 ± 0.052	4.436AspArg: 4.436 ± 0.077	3.306AspSer: 3.306 ± 0.085	2.27AspThr: 2.27 ± 0.062	5.833AspVal: 5.833 ± 0.096	0.804AspTrp: 0.804 ± 0.033	1.419AspTyr: 1.419 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	8.123GluAla: 8.123 ± 0.156	0.455GluCys: 0.455 ± 0.029	3.303GluAsp: 3.303 ± 0.093	4.004GluGlu: 4.004 ± 0.101	1.63GluPhe: 1.63 ± 0.05	5.135GluGly: 5.135 ± 0.098	1.173GluHis: 1.173 ± 0.053	2.742GluIle: 2.742 ± 0.071	1.66GluLys: 1.66 ± 0.061	5.652GluLeu: 5.652 ± 0.11	1.127GluMet: 1.127 ± 0.044	1.345GluAsn: 1.345 ± 0.045	2.916GluPro: 2.916 ± 0.078	1.624GluGln: 1.624 ± 0.055	5.598GluArg: 5.598 ± 0.102	3.293GluSer: 3.293 ± 0.082	2.903GluThr: 2.903 ± 0.064	3.967GluVal: 3.967 ± 0.081	0.806GluTrp: 0.806 ± 0.034	1.288GluTyr: 1.288 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	4.006PheAla: 4.006 ± 0.083	0.25PheCys: 0.25 ± 0.021	2.142PheAsp: 2.142 ± 0.05	1.504PheGlu: 1.504 ± 0.053	1.059PhePhe: 1.059 ± 0.048	3.036PheGly: 3.036 ± 0.08	0.64PheHis: 0.64 ± 0.031	1.161PheIle: 1.161 ± 0.05	0.712PheLys: 0.712 ± 0.035	2.847PheLeu: 2.847 ± 0.071	0.561PheMet: 0.561 ± 0.03	0.679PheAsn: 0.679 ± 0.034	1.532PhePro: 1.532 ± 0.054	0.763PheGln: 0.763 ± 0.033	1.616PheArg: 1.616 ± 0.054	1.987PheSer: 1.987 ± 0.057	1.889PheThr: 1.889 ± 0.053	2.548PheVal: 2.548 ± 0.059	0.373PheTrp: 0.373 ± 0.026	0.695PheTyr: 0.695 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	10.808GlyAla: 10.808 ± 0.163	0.84GlyCys: 0.84 ± 0.037	4.985GlyAsp: 4.985 ± 0.097	5.78GlyGlu: 5.78 ± 0.092	3.121GlyPhe: 3.121 ± 0.071	8.522GlyGly: 8.522 ± 0.153	1.788GlyHis: 1.788 ± 0.051	4.292GlyIle: 4.292 ± 0.084	3.265GlyLys: 3.265 ± 0.083	8.657GlyLeu: 8.657 ± 0.132	2.377GlyMet: 2.377 ± 0.064	1.904GlyAsn: 1.904 ± 0.06	4.303GlyPro: 4.303 ± 0.089	2.845GlyGln: 2.845 ± 0.077	8.266GlyArg: 8.266 ± 0.132	6.013GlySer: 6.013 ± 0.116	5.07GlyThr: 5.07 ± 0.105	7.605GlyVal: 7.605 ± 0.127	1.391GlyTrp: 1.391 ± 0.045	2.256GlyTyr: 2.256 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.191HisAla: 2.191 ± 0.062	0.188HisCys: 0.188 ± 0.016	1.102HisAsp: 1.102 ± 0.043	1.108HisGlu: 1.108 ± 0.046	0.537HisPhe: 0.537 ± 0.032	1.857HisGly: 1.857 ± 0.064	0.403HisHis: 0.403 ± 0.027	0.788HisIle: 0.788 ± 0.037	0.394HisLys: 0.394 ± 0.023	1.637HisLeu: 1.637 ± 0.056	0.381HisMet: 0.381 ± 0.027	0.446HisAsn: 0.446 ± 0.024	1.407HisPro: 1.407 ± 0.047	0.414HisGln: 0.414 ± 0.026	1.626HisArg: 1.626 ± 0.053	1.178HisSer: 1.178 ± 0.044	1.072HisThr: 1.072 ± 0.045	1.622HisVal: 1.622 ± 0.052	0.223HisTrp: 0.223 ± 0.019	0.453HisTyr: 0.453 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.997IleAla: 5.997 ± 0.093	0.348IleCys: 0.348 ± 0.02	3.091IleAsp: 3.091 ± 0.074	2.413IleGlu: 2.413 ± 0.062	1.144IlePhe: 1.144 ± 0.045	4.239IleGly: 4.239 ± 0.082	0.794IleHis: 0.794 ± 0.035	1.41IleIle: 1.41 ± 0.054	0.97IleLys: 0.97 ± 0.043	4.019IleLeu: 4.019 ± 0.081	0.722IleMet: 0.722 ± 0.034	0.843IleAsn: 0.843 ± 0.047	2.547IlePro: 2.547 ± 0.067	1.023IleGln: 1.023 ± 0.04	2.857IleArg: 2.857 ± 0.069	2.329IleSer: 2.329 ± 0.062	2.045IleThr: 2.045 ± 0.06	4.275IleVal: 4.275 ± 0.088	0.377IleTrp: 0.377 ± 0.024	0.711IleTyr: 0.711 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.718LysAla: 3.718 ± 0.087	0.138LysCys: 0.138 ± 0.014	1.609LysAsp: 1.609 ± 0.048	1.508LysGlu: 1.508 ± 0.063	0.629LysPhe: 0.629 ± 0.036	2.41LysGly: 2.41 ± 0.078	0.488LysHis: 0.488 ± 0.028	1.286LysIle: 1.286 ± 0.05	1.322LysLys: 1.322 ± 0.072	2.263LysLeu: 2.263 ± 0.072	0.611LysMet: 0.611 ± 0.032	0.883LysAsn: 0.883 ± 0.05	1.551LysPro: 1.551 ± 0.055	0.705LysGln: 0.705 ± 0.038	2.04LysArg: 2.04 ± 0.066	1.633LysSer: 1.633 ± 0.054	1.64LysThr: 1.64 ± 0.063	2.183LysVal: 2.183 ± 0.07	0.322LysTrp: 0.322 ± 0.029	0.622LysTyr: 0.622 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	13.722LeuAla: 13.722 ± 0.175	0.806LeuCys: 0.806 ± 0.031	5.978LeuAsp: 5.978 ± 0.119	4.934LeuGlu: 4.934 ± 0.097	2.547LeuPhe: 2.547 ± 0.074	8.359LeuGly: 8.359 ± 0.109	1.695LeuHis: 1.695 ± 0.056	3.491LeuIle: 3.491 ± 0.08	2.338LeuLys: 2.338 ± 0.057	8.834LeuLeu: 8.834 ± 0.148	1.797LeuMet: 1.797 ± 0.055	1.947LeuAsn: 1.947 ± 0.058	5.105LeuPro: 5.105 ± 0.1	2.007LeuGln: 2.007 ± 0.061	7.079LeuArg: 7.079 ± 0.133	5.821LeuSer: 5.821 ± 0.1	5.662LeuThr: 5.662 ± 0.103	8.17LeuVal: 8.17 ± 0.143	1.14LeuTrp: 1.14 ± 0.041	1.757LeuTyr: 1.757 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.636MetAla: 2.636 ± 0.061	0.184MetCys: 0.184 ± 0.016	1.158MetAsp: 1.158 ± 0.038	1.01MetGlu: 1.01 ± 0.042	0.567MetPhe: 0.567 ± 0.03	1.777MetGly: 1.777 ± 0.052	0.353MetHis: 0.353 ± 0.025	0.893MetIle: 0.893 ± 0.036	0.627MetLys: 0.627 ± 0.032	1.85MetLeu: 1.85 ± 0.057	0.377MetMet: 0.377 ± 0.024	0.55MetAsn: 0.55 ± 0.029	1.263MetPro: 1.263 ± 0.044	0.486MetGln: 0.486 ± 0.024	1.86MetArg: 1.86 ± 0.054	1.632MetSer: 1.632 ± 0.053	1.472MetThr: 1.472 ± 0.043	1.422MetVal: 1.422 ± 0.053	0.308MetTrp: 0.308 ± 0.021	0.36MetTyr: 0.36 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.64AsnAla: 2.64 ± 0.07	0.151AsnCys: 0.151 ± 0.015	1.121AsnAsp: 1.121 ± 0.048	1.089AsnGlu: 1.089 ± 0.044	0.639AsnPhe: 0.639 ± 0.04	2.068AsnGly: 2.068 ± 0.063	0.426AsnHis: 0.426 ± 0.024	0.816AsnIle: 0.816 ± 0.037	0.599AsnLys: 0.599 ± 0.036	2.059AsnLeu: 2.059 ± 0.056	0.404AsnMet: 0.404 ± 0.025	0.529AsnAsn: 0.529 ± 0.036	1.616AsnPro: 1.616 ± 0.058	0.574AsnGln: 0.574 ± 0.032	1.564AsnArg: 1.564 ± 0.051	1.319AsnSer: 1.319 ± 0.051	1.016AsnThr: 1.016 ± 0.04	1.902AsnVal: 1.902 ± 0.054	0.295AsnTrp: 0.295 ± 0.02	0.557AsnTyr: 0.557 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	7.151ProAla: 7.151 ± 0.138	0.374ProCys: 0.374 ± 0.024	3.718ProAsp: 3.718 ± 0.093	4.004ProGlu: 4.004 ± 0.087	1.544ProPhe: 1.544 ± 0.05	5.872ProGly: 5.872 ± 0.108	1.091ProHis: 1.091 ± 0.043	1.925ProIle: 1.925 ± 0.053	1.36ProLys: 1.36 ± 0.045	4.347ProLeu: 4.347 ± 0.088	0.977ProMet: 0.977 ± 0.038	1.081ProAsn: 1.081 ± 0.046	2.472ProPro: 2.472 ± 0.081	1.501ProGln: 1.501 ± 0.05	3.886ProArg: 3.886 ± 0.075	3.823ProSer: 3.823 ± 0.096	2.727ProThr: 2.727 ± 0.07	4.368ProVal: 4.368 ± 0.095	0.776ProTrp: 0.776 ± 0.035	1.121ProTyr: 1.121 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	4.173GlnAla: 4.173 ± 0.106	0.194GlnCys: 0.194 ± 0.017	1.23GlnAsp: 1.23 ± 0.039	1.35GlnGlu: 1.35 ± 0.048	0.696GlnPhe: 0.696 ± 0.033	1.945GlnGly: 1.945 ± 0.06	0.452GlnHis: 0.452 ± 0.024	1.447GlnIle: 1.447 ± 0.057	0.738GlnLys: 0.738 ± 0.036	2.36GlnLeu: 2.36 ± 0.074	0.568GlnMet: 0.568 ± 0.028	0.593GlnAsn: 0.593 ± 0.033	1.285GlnPro: 1.285 ± 0.053	0.832GlnGln: 0.832 ± 0.052	2.304GlnArg: 2.304 ± 0.058	1.538GlnSer: 1.538 ± 0.047	1.567GlnThr: 1.567 ± 0.045	1.997GlnVal: 1.997 ± 0.06	0.387GlnTrp: 0.387 ± 0.022	0.567GlnTyr: 0.567 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	9.051ArgAla: 9.051 ± 0.147	0.617ArgCys: 0.617 ± 0.03	4.26ArgAsp: 4.26 ± 0.084	5.198ArgGlu: 5.198 ± 0.112	2.351ArgPhe: 2.351 ± 0.063	6.442ArgGly: 6.442 ± 0.12	1.666ArgHis: 1.666 ± 0.058	4.338ArgIle: 4.338 ± 0.092	2.137ArgLys: 2.137 ± 0.06	7.939ArgLeu: 7.939 ± 0.124	1.952ArgMet: 1.952 ± 0.052	1.609ArgAsn: 1.609 ± 0.05	4.208ArgPro: 4.208 ± 0.086	2.299ArgGln: 2.299 ± 0.056	8.287ArgArg: 8.287 ± 0.152	4.725ArgSer: 4.725 ± 0.087	4.378ArgThr: 4.378 ± 0.076	5.551ArgVal: 5.551 ± 0.107	1.175ArgTrp: 1.175 ± 0.038	1.692ArgTyr: 1.692 ± 0.055	0.0ArgXaa: 0.0 ± 0.0
Ser	7.567SerAla: 7.567 ± 0.13	0.522SerCys: 0.522 ± 0.025	3.291SerAsp: 3.291 ± 0.069	3.016SerGlu: 3.016 ± 0.068	2.027SerPhe: 2.027 ± 0.055	6.696SerGly: 6.696 ± 0.103	1.262SerHis: 1.262 ± 0.043	2.693SerIle: 2.693 ± 0.062	1.773SerLys: 1.773 ± 0.065	5.801SerLeu: 5.801 ± 0.112	1.367SerMet: 1.367 ± 0.046	1.319SerAsn: 1.319 ± 0.054	3.833SerPro: 3.833 ± 0.098	1.916SerGln: 1.916 ± 0.056	4.893SerArg: 4.893 ± 0.096	4.417SerSer: 4.417 ± 0.121	3.567SerThr: 3.567 ± 0.085	4.547SerVal: 4.547 ± 0.089	0.878SerTrp: 0.878 ± 0.036	1.327SerTyr: 1.327 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	6.797ThrAla: 6.797 ± 0.109	0.463ThrCys: 0.463 ± 0.024	2.842ThrAsp: 2.842 ± 0.07	2.468ThrGlu: 2.468 ± 0.068	1.568ThrPhe: 1.568 ± 0.048	5.519ThrGly: 5.519 ± 0.089	1.033ThrHis: 1.033 ± 0.039	2.414ThrIle: 2.414 ± 0.068	1.347ThrLys: 1.347 ± 0.052	5.067ThrLeu: 5.067 ± 0.094	1.148ThrMet: 1.148 ± 0.038	1.108ThrAsn: 1.108 ± 0.045	3.492ThrPro: 3.492 ± 0.08	1.296ThrGln: 1.296 ± 0.047	3.567ThrArg: 3.567 ± 0.077	3.437ThrSer: 3.437 ± 0.083	3.029ThrThr: 3.029 ± 0.086	5.206ThrVal: 5.206 ± 0.109	0.814ThrTrp: 0.814 ± 0.033	1.121ThrTyr: 1.121 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	10.272ValAla: 10.272 ± 0.151	0.886ValCys: 0.886 ± 0.036	5.544ValAsp: 5.544 ± 0.103	5.237ValGlu: 5.237 ± 0.112	2.755ValPhe: 2.755 ± 0.061	7.033ValGly: 7.033 ± 0.115	1.532ValHis: 1.532 ± 0.051	3.234ValIle: 3.234 ± 0.072	2.342ValLys: 2.342 ± 0.068	7.771ValLeu: 7.771 ± 0.107	1.501ValMet: 1.501 ± 0.049	1.935ValAsn: 1.935 ± 0.063	4.293ValPro: 4.293 ± 0.073	1.869ValGln: 1.869 ± 0.056	6.48ValArg: 6.48 ± 0.106	5.292ValSer: 5.292 ± 0.087	4.903ValThr: 4.903 ± 0.092	8.05ValVal: 8.05 ± 0.141	1.042ValTrp: 1.042 ± 0.04	1.787ValTyr: 1.787 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	1.434TrpAla: 1.434 ± 0.046	0.154TrpCys: 0.154 ± 0.014	0.764TrpAsp: 0.764 ± 0.036	0.709TrpGlu: 0.709 ± 0.034	0.478TrpPhe: 0.478 ± 0.026	0.991TrpGly: 0.991 ± 0.043	0.278TrpHis: 0.278 ± 0.021	0.676TrpIle: 0.676 ± 0.03	0.452TrpLys: 0.452 ± 0.026	1.399TrpLeu: 1.399 ± 0.049	0.342TrpMet: 0.342 ± 0.026	0.46TrpAsn: 0.46 ± 0.028	0.647TrpPro: 0.647 ± 0.028	0.45TrpGln: 0.45 ± 0.025	1.281TrpArg: 1.281 ± 0.043	0.788TrpSer: 0.788 ± 0.038	0.862TrpThr: 0.862 ± 0.037	0.902TrpVal: 0.902 ± 0.037	0.285TrpTrp: 0.285 ± 0.021	0.299TrpTyr: 0.299 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.531TyrAla: 2.531 ± 0.061	0.188TyrCys: 0.188 ± 0.02	1.311TyrAsp: 1.311 ± 0.045	1.348TyrGlu: 1.348 ± 0.044	0.715TyrPhe: 0.715 ± 0.038	2.092TyrGly: 2.092 ± 0.055	0.387TyrHis: 0.387 ± 0.023	0.783TyrIle: 0.783 ± 0.041	0.517TyrLys: 0.517 ± 0.033	2.111TyrLeu: 2.111 ± 0.057	0.413TyrMet: 0.413 ± 0.023	0.573TyrAsn: 0.573 ± 0.032	1.098TyrPro: 1.098 ± 0.039	0.541TyrGln: 0.541 ± 0.032	1.754TyrArg: 1.754 ± 0.055	1.322TyrSer: 1.322 ± 0.043	1.184TyrThr: 1.184 ± 0.048	1.752TyrVal: 1.752 ± 0.046	0.342TyrTrp: 0.342 ± 0.02	0.517TyrTyr: 0.517 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2320 proteins (695025 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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