Amino acid dipepetide frequency for Leucothrix arctica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.07AlaAla: 8.07 ± 0.115	0.874AlaCys: 0.874 ± 0.027	4.853AlaAsp: 4.853 ± 0.066	5.493AlaGlu: 5.493 ± 0.071	3.325AlaPhe: 3.325 ± 0.064	6.374AlaGly: 6.374 ± 0.095	1.555AlaHis: 1.555 ± 0.038	5.682AlaIle: 5.682 ± 0.082	4.682AlaLys: 4.682 ± 0.073	9.121AlaLeu: 9.121 ± 0.097	2.406AlaMet: 2.406 ± 0.047	3.328AlaAsn: 3.328 ± 0.057	3.01AlaPro: 3.01 ± 0.085	3.233AlaGln: 3.233 ± 0.053	3.555AlaArg: 3.555 ± 0.057	5.832AlaSer: 5.832 ± 0.079	4.895AlaThr: 4.895 ± 0.11	6.045AlaVal: 6.045 ± 0.082	1.073AlaTrp: 1.073 ± 0.03	2.469AlaTyr: 2.469 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.745CysAla: 0.745 ± 0.029	0.132CysCys: 0.132 ± 0.011	0.624CysAsp: 0.624 ± 0.036	0.545CysGlu: 0.545 ± 0.03	0.436CysPhe: 0.436 ± 0.017	0.833CysGly: 0.833 ± 0.027	0.292CysHis: 0.292 ± 0.017	0.608CysIle: 0.608 ± 0.022	0.419CysLys: 0.419 ± 0.019	0.938CysLeu: 0.938 ± 0.03	0.197CysMet: 0.197 ± 0.012	0.37CysAsn: 0.37 ± 0.018	0.465CysPro: 0.465 ± 0.028	0.35CysGln: 0.35 ± 0.018	0.441CysArg: 0.441 ± 0.019	0.701CysSer: 0.701 ± 0.021	0.475CysThr: 0.475 ± 0.019	0.6CysVal: 0.6 ± 0.019	0.122CysTrp: 0.122 ± 0.012	0.31CysTyr: 0.31 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.889AspAla: 4.889 ± 0.079	0.55AspCys: 0.55 ± 0.021	3.6AspAsp: 3.6 ± 0.063	4.067AspGlu: 4.067 ± 0.058	2.569AspPhe: 2.569 ± 0.045	4.215AspGly: 4.215 ± 0.11	1.092AspHis: 1.092 ± 0.029	3.94AspIle: 3.94 ± 0.054	3.216AspLys: 3.216 ± 0.065	5.538AspLeu: 5.538 ± 0.071	1.343AspMet: 1.343 ± 0.032	2.605AspAsn: 2.605 ± 0.06	2.259AspPro: 2.259 ± 0.053	2.156AspGln: 2.156 ± 0.044	2.416AspArg: 2.416 ± 0.043	3.818AspSer: 3.818 ± 0.081	3.412AspThr: 3.412 ± 0.069	4.01AspVal: 4.01 ± 0.061	0.879AspTrp: 0.879 ± 0.027	2.147AspTyr: 2.147 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	5.424GluAla: 5.424 ± 0.073	0.497GluCys: 0.497 ± 0.022	3.103GluAsp: 3.103 ± 0.056	3.592GluGlu: 3.592 ± 0.058	2.188GluPhe: 2.188 ± 0.049	3.771GluGly: 3.771 ± 0.059	1.416GluHis: 1.416 ± 0.041	3.872GluIle: 3.872 ± 0.059	3.789GluLys: 3.789 ± 0.064	6.352GluLeu: 6.352 ± 0.096	1.616GluMet: 1.616 ± 0.035	2.652GluAsn: 2.652 ± 0.046	1.943GluPro: 1.943 ± 0.043	3.095GluGln: 3.095 ± 0.06	3.058GluArg: 3.058 ± 0.055	4.163GluSer: 4.163 ± 0.061	3.426GluThr: 3.426 ± 0.058	4.497GluVal: 4.497 ± 0.066	0.809GluTrp: 0.809 ± 0.026	1.884GluTyr: 1.884 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.358PheAla: 3.358 ± 0.054	0.445PheCys: 0.445 ± 0.021	2.708PheAsp: 2.708 ± 0.053	2.437PheGlu: 2.437 ± 0.045	1.783PhePhe: 1.783 ± 0.043	3.043PheGly: 3.043 ± 0.053	0.758PheHis: 0.758 ± 0.023	2.608PheIle: 2.608 ± 0.05	2.065PheLys: 2.065 ± 0.046	3.614PheLeu: 3.614 ± 0.063	1.035PheMet: 1.035 ± 0.027	1.795PheAsn: 1.795 ± 0.037	1.451PhePro: 1.451 ± 0.034	1.22PheGln: 1.22 ± 0.029	1.562PheArg: 1.562 ± 0.034	3.273PheSer: 3.273 ± 0.045	2.436PheThr: 2.436 ± 0.051	2.724PheVal: 2.724 ± 0.047	0.544PheTrp: 0.544 ± 0.02	1.358PheTyr: 1.358 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.415GlyAla: 5.415 ± 0.075	0.815GlyCys: 0.815 ± 0.043	3.937GlyAsp: 3.937 ± 0.071	4.203GlyGlu: 4.203 ± 0.07	3.176GlyPhe: 3.176 ± 0.051	5.013GlyGly: 5.013 ± 0.068	1.492GlyHis: 1.492 ± 0.031	4.68GlyIle: 4.68 ± 0.067	4.002GlyLys: 4.002 ± 0.061	7.162GlyLeu: 7.162 ± 0.088	2.012GlyMet: 2.012 ± 0.046	2.897GlyAsn: 2.897 ± 0.074	1.666GlyPro: 1.666 ± 0.04	2.516GlyGln: 2.516 ± 0.05	3.073GlyArg: 3.073 ± 0.057	4.643GlySer: 4.643 ± 0.067	3.933GlyThr: 3.933 ± 0.098	5.374GlyVal: 5.374 ± 0.075	0.956GlyTrp: 0.956 ± 0.028	2.404GlyTyr: 2.404 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.586HisAla: 1.586 ± 0.039	0.262HisCys: 0.262 ± 0.014	1.223HisAsp: 1.223 ± 0.033	1.172HisGlu: 1.172 ± 0.03	0.936HisPhe: 0.936 ± 0.027	1.442HisGly: 1.442 ± 0.04	0.588HisHis: 0.588 ± 0.024	1.315HisIle: 1.315 ± 0.033	1.0HisLys: 1.0 ± 0.03	2.073HisLeu: 2.073 ± 0.042	0.511HisMet: 0.511 ± 0.021	0.815HisAsn: 0.815 ± 0.024	1.093HisPro: 1.093 ± 0.031	0.865HisGln: 0.865 ± 0.028	1.016HisArg: 1.016 ± 0.03	1.376HisSer: 1.376 ± 0.037	1.091HisThr: 1.091 ± 0.034	1.243HisVal: 1.243 ± 0.029	0.342HisTrp: 0.342 ± 0.016	0.815HisTyr: 0.815 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.083IleAla: 6.083 ± 0.078	0.643IleCys: 0.643 ± 0.022	4.163IleAsp: 4.163 ± 0.059	4.263IleGlu: 4.263 ± 0.058	2.197IlePhe: 2.197 ± 0.051	4.623IleGly: 4.623 ± 0.07	1.249IleHis: 1.249 ± 0.032	3.832IleIle: 3.832 ± 0.065	3.429IleLys: 3.429 ± 0.054	5.573IleLeu: 5.573 ± 0.074	1.368IleMet: 1.368 ± 0.036	2.941IleAsn: 2.941 ± 0.052	2.934IlePro: 2.934 ± 0.046	2.102IleGln: 2.102 ± 0.04	2.825IleArg: 2.825 ± 0.045	4.714IleSer: 4.714 ± 0.059	4.034IleThr: 4.034 ± 0.075	4.079IleVal: 4.079 ± 0.061	0.661IleTrp: 0.661 ± 0.022	1.713IleTyr: 1.713 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.88LysAla: 4.88 ± 0.074	0.308LysCys: 0.308 ± 0.016	3.015LysAsp: 3.015 ± 0.065	3.203LysGlu: 3.203 ± 0.056	1.516LysPhe: 1.516 ± 0.038	3.475LysGly: 3.475 ± 0.061	1.327LysHis: 1.327 ± 0.032	3.129LysIle: 3.129 ± 0.048	3.334LysLys: 3.334 ± 0.076	5.251LysLeu: 5.251 ± 0.073	1.34LysMet: 1.34 ± 0.034	2.316LysAsn: 2.316 ± 0.048	2.499LysPro: 2.499 ± 0.058	2.794LysGln: 2.794 ± 0.049	2.884LysArg: 2.884 ± 0.052	3.658LysSer: 3.658 ± 0.059	3.276LysThr: 3.276 ± 0.049	3.834LysVal: 3.834 ± 0.056	0.554LysTrp: 0.554 ± 0.019	1.46LysTyr: 1.46 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	9.012LeuAla: 9.012 ± 0.1	0.982LeuCys: 0.982 ± 0.029	5.888LeuAsp: 5.888 ± 0.069	6.032LeuGlu: 6.032 ± 0.073	4.167LeuPhe: 4.167 ± 0.066	6.895LeuGly: 6.895 ± 0.088	1.955LeuHis: 1.955 ± 0.038	6.377LeuIle: 6.377 ± 0.079	5.715LeuLys: 5.715 ± 0.074	10.622LeuLeu: 10.622 ± 0.136	2.577LeuMet: 2.577 ± 0.045	4.391LeuAsn: 4.391 ± 0.062	4.541LeuPro: 4.541 ± 0.069	3.525LeuGln: 3.525 ± 0.064	4.457LeuArg: 4.457 ± 0.069	8.284LeuSer: 8.284 ± 0.091	5.997LeuThr: 5.997 ± 0.077	6.789LeuVal: 6.789 ± 0.077	1.119LeuTrp: 1.119 ± 0.03	2.623LeuTyr: 2.623 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.283MetAla: 2.283 ± 0.047	0.182MetCys: 0.182 ± 0.012	1.317MetAsp: 1.317 ± 0.034	1.217MetGlu: 1.217 ± 0.029	0.845MetPhe: 0.845 ± 0.029	1.715MetGly: 1.715 ± 0.038	0.465MetHis: 0.465 ± 0.018	1.557MetIle: 1.557 ± 0.032	1.626MetLys: 1.626 ± 0.034	2.583MetLeu: 2.583 ± 0.05	0.747MetMet: 0.747 ± 0.022	1.097MetAsn: 1.097 ± 0.027	1.184MetPro: 1.184 ± 0.03	1.033MetGln: 1.033 ± 0.027	1.192MetArg: 1.192 ± 0.032	2.039MetSer: 2.039 ± 0.038	1.655MetThr: 1.655 ± 0.036	1.715MetVal: 1.715 ± 0.04	0.213MetTrp: 0.213 ± 0.012	0.513MetTyr: 0.513 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.394AsnAla: 3.394 ± 0.054	0.421AsnCys: 0.421 ± 0.018	2.645AsnAsp: 2.645 ± 0.064	2.393AsnGlu: 2.393 ± 0.043	1.586AsnPhe: 1.586 ± 0.032	3.028AsnGly: 3.028 ± 0.063	0.928AsnHis: 0.928 ± 0.026	2.948AsnIle: 2.948 ± 0.056	2.343AsnLys: 2.343 ± 0.049	3.858AsnLeu: 3.858 ± 0.06	0.936AsnMet: 0.936 ± 0.027	2.063AsnAsn: 2.063 ± 0.048	2.107AsnPro: 2.107 ± 0.052	1.633AsnGln: 1.633 ± 0.033	1.878AsnArg: 1.878 ± 0.037	2.704AsnSer: 2.704 ± 0.053	2.758AsnThr: 2.758 ± 0.068	2.704AsnVal: 2.704 ± 0.057	0.6AsnTrp: 0.6 ± 0.024	1.413AsnTyr: 1.413 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	3.386ProAla: 3.386 ± 0.089	0.294ProCys: 0.294 ± 0.02	2.548ProAsp: 2.548 ± 0.047	3.361ProGlu: 3.361 ± 0.052	1.685ProPhe: 1.685 ± 0.035	2.101ProGly: 2.101 ± 0.041	0.792ProHis: 0.792 ± 0.026	2.442ProIle: 2.442 ± 0.043	2.053ProLys: 2.053 ± 0.045	3.836ProLeu: 3.836 ± 0.052	1.006ProMet: 1.006 ± 0.027	1.715ProAsn: 1.715 ± 0.038	1.296ProPro: 1.296 ± 0.038	1.363ProGln: 1.363 ± 0.036	1.405ProArg: 1.405 ± 0.039	2.889ProSer: 2.889 ± 0.058	2.398ProThr: 2.398 ± 0.084	3.253ProVal: 3.253 ± 0.057	0.531ProTrp: 0.531 ± 0.023	1.282ProTyr: 1.282 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.819GlnAla: 3.819 ± 0.061	0.369GlnCys: 0.369 ± 0.023	1.821GlnAsp: 1.821 ± 0.046	2.056GlnGlu: 2.056 ± 0.046	1.429GlnPhe: 1.429 ± 0.03	2.558GlnGly: 2.558 ± 0.051	0.953GlnHis: 0.953 ± 0.029	2.17GlnIle: 2.17 ± 0.044	1.999GlnLys: 1.999 ± 0.044	4.467GlnLeu: 4.467 ± 0.078	0.902GlnMet: 0.902 ± 0.027	1.413GlnAsn: 1.413 ± 0.034	1.473GlnPro: 1.473 ± 0.036	2.497GlnGln: 2.497 ± 0.071	2.22GlnArg: 2.22 ± 0.044	2.74GlnSer: 2.74 ± 0.046	2.146GlnThr: 2.146 ± 0.046	2.689GlnVal: 2.689 ± 0.045	0.55GlnTrp: 0.55 ± 0.02	1.241GlnTyr: 1.241 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	3.263ArgAla: 3.263 ± 0.052	0.467ArgCys: 0.467 ± 0.018	2.439ArgAsp: 2.439 ± 0.041	2.89ArgGlu: 2.89 ± 0.058	2.162ArgPhe: 2.162 ± 0.036	2.697ArgGly: 2.697 ± 0.046	0.998ArgHis: 0.998 ± 0.029	2.915ArgIle: 2.915 ± 0.053	2.484ArgLys: 2.484 ± 0.045	4.96ArgLeu: 4.96 ± 0.075	1.267ArgMet: 1.267 ± 0.029	1.891ArgAsn: 1.891 ± 0.04	1.601ArgPro: 1.601 ± 0.033	1.978ArgGln: 1.978 ± 0.034	2.246ArgArg: 2.246 ± 0.05	2.803ArgSer: 2.803 ± 0.047	2.237ArgThr: 2.237 ± 0.049	3.174ArgVal: 3.174 ± 0.048	0.683ArgTrp: 0.683 ± 0.022	1.707ArgTyr: 1.707 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.675SerAla: 5.675 ± 0.074	0.717SerCys: 0.717 ± 0.039	4.352SerAsp: 4.352 ± 0.069	4.049SerGlu: 4.049 ± 0.053	3.154SerPhe: 3.154 ± 0.06	5.548SerGly: 5.548 ± 0.086	1.472SerHis: 1.472 ± 0.037	4.46SerIle: 4.46 ± 0.061	3.661SerLys: 3.661 ± 0.06	7.429SerLeu: 7.429 ± 0.09	1.807SerMet: 1.807 ± 0.045	3.03SerAsn: 3.03 ± 0.062	2.679SerPro: 2.679 ± 0.045	2.559SerGln: 2.559 ± 0.054	3.161SerArg: 3.161 ± 0.057	5.016SerSer: 5.016 ± 0.081	3.977SerThr: 3.977 ± 0.066	5.086SerVal: 5.086 ± 0.074	0.898SerTrp: 0.898 ± 0.029	2.272SerTyr: 2.272 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	5.169ThrAla: 5.169 ± 0.091	0.473ThrCys: 0.473 ± 0.022	3.608ThrAsp: 3.608 ± 0.077	3.437ThrGlu: 3.437 ± 0.055	2.161ThrPhe: 2.161 ± 0.039	4.412ThrGly: 4.412 ± 0.09	1.238ThrHis: 1.238 ± 0.031	3.623ThrIle: 3.623 ± 0.065	2.559ThrLys: 2.559 ± 0.046	6.636ThrLeu: 6.636 ± 0.088	1.223ThrMet: 1.223 ± 0.031	2.34ThrAsn: 2.34 ± 0.071	3.019ThrPro: 3.019 ± 0.089	2.287ThrGln: 2.287 ± 0.06	2.35ThrArg: 2.35 ± 0.045	3.898ThrSer: 3.898 ± 0.069	3.582ThrThr: 3.582 ± 0.093	4.395ThrVal: 4.395 ± 0.096	0.693ThrTrp: 0.693 ± 0.027	1.693ThrTyr: 1.693 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	6.255ValAla: 6.255 ± 0.094	0.692ValCys: 0.692 ± 0.024	4.287ValAsp: 4.287 ± 0.088	4.391ValGlu: 4.391 ± 0.065	2.93ValPhe: 2.93 ± 0.051	4.746ValGly: 4.746 ± 0.07	1.188ValHis: 1.188 ± 0.027	4.9ValIle: 4.9 ± 0.066	3.532ValLys: 3.532 ± 0.055	7.025ValLeu: 7.025 ± 0.076	1.917ValMet: 1.917 ± 0.041	2.975ValAsn: 2.975 ± 0.062	2.645ValPro: 2.645 ± 0.046	2.042ValGln: 2.042 ± 0.038	2.789ValArg: 2.789 ± 0.047	5.354ValSer: 5.354 ± 0.066	4.612ValThr: 4.612 ± 0.1	5.343ValVal: 5.343 ± 0.076	0.764ValTrp: 0.764 ± 0.023	1.919ValTyr: 1.919 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.862TrpAla: 0.862 ± 0.027	0.137TrpCys: 0.137 ± 0.011	0.712TrpAsp: 0.712 ± 0.026	0.647TrpGlu: 0.647 ± 0.025	0.593TrpPhe: 0.593 ± 0.021	0.776TrpGly: 0.776 ± 0.025	0.316TrpHis: 0.316 ± 0.016	0.656TrpIle: 0.656 ± 0.023	0.647TrpLys: 0.647 ± 0.021	1.583TrpLeu: 1.583 ± 0.04	0.379TrpMet: 0.379 ± 0.016	0.488TrpAsn: 0.488 ± 0.019	0.454TrpPro: 0.454 ± 0.019	0.687TrpGln: 0.687 ± 0.026	0.65TrpArg: 0.65 ± 0.022	0.869TrpSer: 0.869 ± 0.028	0.624TrpThr: 0.624 ± 0.028	0.949TrpVal: 0.949 ± 0.029	0.194TrpTrp: 0.194 ± 0.013	0.394TrpTyr: 0.394 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.309TyrAla: 2.309 ± 0.045	0.343TyrCys: 0.343 ± 0.019	1.876TyrAsp: 1.876 ± 0.05	1.698TyrGlu: 1.698 ± 0.039	1.381TyrPhe: 1.381 ± 0.038	2.104TyrGly: 2.104 ± 0.042	0.69TyrHis: 0.69 ± 0.026	1.712TyrIle: 1.712 ± 0.038	1.5TyrLys: 1.5 ± 0.04	3.327TyrLeu: 3.327 ± 0.049	0.592TyrMet: 0.592 ± 0.022	1.211TyrAsn: 1.211 ± 0.033	1.317TyrPro: 1.317 ± 0.031	1.576TyrGln: 1.576 ± 0.041	1.685TyrArg: 1.685 ± 0.031	2.228TyrSer: 2.228 ± 0.05	1.834TyrThr: 1.834 ± 0.046	1.802TyrVal: 1.802 ± 0.044	0.431TyrTrp: 0.431 ± 0.017	1.013TyrTyr: 1.013 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4192 proteins (1404415 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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