Amino acid dipepetide frequency for Phytohabitans flavus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
22.981AlaAla: 22.981 ± 0.167
1.045AlaCys: 1.045 ± 0.02
8.077AlaAsp: 8.077 ± 0.059
8.082AlaGlu: 8.082 ± 0.071
3.591AlaPhe: 3.591 ± 0.037
14.011AlaGly: 14.011 ± 0.101
2.554AlaHis: 2.554 ± 0.037
4.621AlaIle: 4.621 ± 0.044
2.489AlaLys: 2.489 ± 0.038
14.162AlaLeu: 14.162 ± 0.098
2.608AlaMet: 2.608 ± 0.03
2.38AlaAsn: 2.38 ± 0.035
6.881AlaPro: 6.881 ± 0.059
3.708AlaGln: 3.708 ± 0.052
10.252AlaArg: 10.252 ± 0.069
6.452AlaSer: 6.452 ± 0.05
8.26AlaThr: 8.26 ± 0.061
12.506AlaVal: 12.506 ± 0.081
2.01AlaTrp: 2.01 ± 0.029
2.8AlaTyr: 2.8 ± 0.032
0.0AlaXaa: 0.0 ± 0.0
Cys
1.013CysAla: 1.013 ± 0.02
0.144CysCys: 0.144 ± 0.008
0.469CysAsp: 0.469 ± 0.013
0.328CysGlu: 0.328 ± 0.01
0.2CysPhe: 0.2 ± 0.008
0.936CysGly: 0.936 ± 0.019
0.193CysHis: 0.193 ± 0.007
0.143CysIle: 0.143 ± 0.007
0.102CysLys: 0.102 ± 0.005
0.672CysLeu: 0.672 ± 0.017
0.135CysMet: 0.135 ± 0.007
0.125CysAsn: 0.125 ± 0.007
0.501CysPro: 0.501 ± 0.015
0.199CysGln: 0.199 ± 0.008
0.684CysArg: 0.684 ± 0.017
0.47CysSer: 0.47 ± 0.013
0.483CysThr: 0.483 ± 0.015
0.604CysVal: 0.604 ± 0.015
0.166CysTrp: 0.166 ± 0.008
0.16CysTyr: 0.16 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
7.429AspAla: 7.429 ± 0.062
0.349AspCys: 0.349 ± 0.012
3.523AspAsp: 3.523 ± 0.043
3.818AspGlu: 3.818 ± 0.04
1.576AspPhe: 1.576 ± 0.027
6.433AspGly: 6.433 ± 0.064
1.251AspHis: 1.251 ± 0.019
1.842AspIle: 1.842 ± 0.026
1.02AspLys: 1.02 ± 0.023
6.714AspLeu: 6.714 ± 0.048
0.786AspMet: 0.786 ± 0.016
1.071AspAsn: 1.071 ± 0.023
4.699AspPro: 4.699 ± 0.048
1.704AspGln: 1.704 ± 0.03
5.023AspArg: 5.023 ± 0.045
2.354AspSer: 2.354 ± 0.029
2.839AspThr: 2.839 ± 0.032
4.944AspVal: 4.944 ± 0.041
0.957AspTrp: 0.957 ± 0.021
1.179AspTyr: 1.179 ± 0.023
0.0AspXaa: 0.0 ± 0.0
Glu
6.907GluAla: 6.907 ± 0.065
0.353GluCys: 0.353 ± 0.014
2.293GluAsp: 2.293 ± 0.032
2.713GluGlu: 2.713 ± 0.035
1.467GluPhe: 1.467 ± 0.027
3.583GluGly: 3.583 ± 0.035
1.289GluHis: 1.289 ± 0.023
2.135GluIle: 2.135 ± 0.03
1.025GluLys: 1.025 ± 0.024
5.973GluLeu: 5.973 ± 0.055
0.863GluMet: 0.863 ± 0.019
0.759GluAsn: 0.759 ± 0.019
3.393GluPro: 3.393 ± 0.046
2.016GluGln: 2.016 ± 0.03
5.247GluArg: 5.247 ± 0.049
2.352GluSer: 2.352 ± 0.031
2.504GluThr: 2.504 ± 0.03
4.705GluVal: 4.705 ± 0.045
0.812GluTrp: 0.812 ± 0.016
1.159GluTyr: 1.159 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
3.905PheAla: 3.905 ± 0.046
0.223PheCys: 0.223 ± 0.009
2.089PheAsp: 2.089 ± 0.03
1.391PheGlu: 1.391 ± 0.023
0.876PhePhe: 0.876 ± 0.021
3.059PheGly: 3.059 ± 0.037
0.547PheHis: 0.547 ± 0.014
0.734PheIle: 0.734 ± 0.018
0.429PheLys: 0.429 ± 0.014
2.494PheLeu: 2.494 ± 0.034
0.384PheMet: 0.384 ± 0.013
0.616PheAsn: 0.616 ± 0.017
1.374PhePro: 1.374 ± 0.022
0.739PheGln: 0.739 ± 0.017
1.858PheArg: 1.858 ± 0.023
1.375PheSer: 1.375 ± 0.025
1.906PheThr: 1.906 ± 0.025
2.505PheVal: 2.505 ± 0.031
0.452PheTrp: 0.452 ± 0.014
0.608PheTyr: 0.608 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
10.886GlyAla: 10.886 ± 0.066
0.824GlyCys: 0.824 ± 0.019
5.277GlyAsp: 5.277 ± 0.053
4.683GlyGlu: 4.683 ± 0.045
2.827GlyPhe: 2.827 ± 0.034
8.886GlyGly: 8.886 ± 0.084
2.101GlyHis: 2.101 ± 0.029
3.417GlyIle: 3.417 ± 0.036
1.982GlyLys: 1.982 ± 0.031
9.231GlyLeu: 9.231 ± 0.065
1.929GlyMet: 1.929 ± 0.027
1.88GlyAsn: 1.88 ± 0.04
5.177GlyPro: 5.177 ± 0.045
2.933GlyGln: 2.933 ± 0.035
7.608GlyArg: 7.608 ± 0.053
5.052GlySer: 5.052 ± 0.048
5.926GlyThr: 5.926 ± 0.05
7.873GlyVal: 7.873 ± 0.073
1.903GlyTrp: 1.903 ± 0.031
2.415GlyTyr: 2.415 ± 0.032
0.0GlyXaa: 0.0 ± 0.0
His
2.447HisAla: 2.447 ± 0.033
0.179HisCys: 0.179 ± 0.008
1.284HisAsp: 1.284 ± 0.023
1.049HisGlu: 1.049 ± 0.019
0.55HisPhe: 0.55 ± 0.016
2.017HisGly: 2.017 ± 0.029
0.618HisHis: 0.618 ± 0.018
0.631HisIle: 0.631 ± 0.015
0.3HisLys: 0.3 ± 0.01
2.403HisLeu: 2.403 ± 0.037
0.304HisMet: 0.304 ± 0.011
0.399HisAsn: 0.399 ± 0.012
1.66HisPro: 1.66 ± 0.025
0.599HisGln: 0.599 ± 0.016
1.988HisArg: 1.988 ± 0.031
0.927HisSer: 0.927 ± 0.018
1.111HisThr: 1.111 ± 0.021
1.658HisVal: 1.658 ± 0.026
0.344HisTrp: 0.344 ± 0.011
0.433HisTyr: 0.433 ± 0.013
0.0HisXaa: 0.0 ± 0.0
Ile
5.137IleAla: 5.137 ± 0.046
0.295IleCys: 0.295 ± 0.011
2.435IleAsp: 2.435 ± 0.029
2.034IleGlu: 2.034 ± 0.028
0.878IlePhe: 0.878 ± 0.019
3.62IleGly: 3.62 ± 0.044
0.626IleHis: 0.626 ± 0.015
0.969IleIle: 0.969 ± 0.02
0.675IleLys: 0.675 ± 0.015
2.595IleLeu: 2.595 ± 0.035
0.474IleMet: 0.474 ± 0.014
0.776IleAsn: 0.776 ± 0.016
1.819IlePro: 1.819 ± 0.026
0.821IleGln: 0.821 ± 0.017
2.53IleArg: 2.53 ± 0.03
1.842IleSer: 1.842 ± 0.028
2.155IleThr: 2.155 ± 0.035
3.08IleVal: 3.08 ± 0.036
0.463IleTrp: 0.463 ± 0.014
0.654IleTyr: 0.654 ± 0.013
0.0IleXaa: 0.0 ± 0.0
Lys
2.335LysAla: 2.335 ± 0.039
0.113LysCys: 0.113 ± 0.009
0.86LysAsp: 0.86 ± 0.021
0.825LysGlu: 0.825 ± 0.021
0.415LysPhe: 0.415 ± 0.014
1.315LysGly: 1.315 ± 0.025
0.374LysHis: 0.374 ± 0.012
0.754LysIle: 0.754 ± 0.019
0.442LysLys: 0.442 ± 0.018
1.817LysLeu: 1.817 ± 0.027
0.332LysMet: 0.332 ± 0.011
0.344LysAsn: 0.344 ± 0.014
1.212LysPro: 1.212 ± 0.022
0.575LysGln: 0.575 ± 0.016
1.339LysArg: 1.339 ± 0.026
0.932LysSer: 0.932 ± 0.018
1.079LysThr: 1.079 ± 0.021
1.677LysVal: 1.677 ± 0.031
0.264LysTrp: 0.264 ± 0.01
0.382LysTyr: 0.382 ± 0.012
0.0LysXaa: 0.0 ± 0.0
Leu
16.223LeuAla: 16.223 ± 0.114
0.731LeuCys: 0.731 ± 0.017
6.924LeuAsp: 6.924 ± 0.059
4.126LeuGlu: 4.126 ± 0.042
2.601LeuPhe: 2.601 ± 0.039
8.998LeuGly: 8.998 ± 0.065
2.105LeuHis: 2.105 ± 0.033
3.248LeuIle: 3.248 ± 0.039
1.454LeuLys: 1.454 ± 0.025
10.841LeuLeu: 10.841 ± 0.086
1.512LeuMet: 1.512 ± 0.025
1.683LeuAsn: 1.683 ± 0.027
6.352LeuPro: 6.352 ± 0.054
2.007LeuGln: 2.007 ± 0.027
8.814LeuArg: 8.814 ± 0.072
5.307LeuSer: 5.307 ± 0.042
6.363LeuThr: 6.363 ± 0.047
9.5LeuVal: 9.5 ± 0.071
1.302LeuTrp: 1.302 ± 0.025
1.808LeuTyr: 1.808 ± 0.025
0.0LeuXaa: 0.0 ± 0.0
Met
2.265MetAla: 2.265 ± 0.028
0.127MetCys: 0.127 ± 0.007
0.829MetAsp: 0.829 ± 0.02
0.662MetGlu: 0.662 ± 0.014
0.505MetPhe: 0.505 ± 0.015
1.235MetGly: 1.235 ± 0.021
0.326MetHis: 0.326 ± 0.011
0.674MetIle: 0.674 ± 0.016
0.315MetLys: 0.315 ± 0.012
1.859MetLeu: 1.859 ± 0.026
0.296MetMet: 0.296 ± 0.011
0.352MetAsn: 0.352 ± 0.011
1.138MetPro: 1.138 ± 0.02
0.418MetGln: 0.418 ± 0.013
1.581MetArg: 1.581 ± 0.026
1.235MetSer: 1.235 ± 0.02
1.424MetThr: 1.424 ± 0.024
1.435MetVal: 1.435 ± 0.023
0.261MetTrp: 0.261 ± 0.012
0.331MetTyr: 0.331 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
2.379AsnAla: 2.379 ± 0.031
0.161AsnCys: 0.161 ± 0.008
1.01AsnAsp: 1.01 ± 0.021
0.833AsnGlu: 0.833 ± 0.017
0.549AsnPhe: 0.549 ± 0.014
2.063AsnGly: 2.063 ± 0.04
0.367AsnHis: 0.367 ± 0.011
0.651AsnIle: 0.651 ± 0.017
0.351AsnLys: 0.351 ± 0.012
1.797AsnLeu: 1.797 ± 0.031
0.266AsnMet: 0.266 ± 0.01
0.538AsnAsn: 0.538 ± 0.02
1.507AsnPro: 1.507 ± 0.025
0.6AsnGln: 0.6 ± 0.016
1.299AsnArg: 1.299 ± 0.022
0.927AsnSer: 0.927 ± 0.019
1.133AsnThr: 1.133 ± 0.028
1.528AsnVal: 1.528 ± 0.029
0.315AsnTrp: 0.315 ± 0.012
0.45AsnTyr: 0.45 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
9.457ProAla: 9.457 ± 0.071
0.342ProCys: 0.342 ± 0.012
4.767ProAsp: 4.767 ± 0.041
3.751ProGlu: 3.751 ± 0.037
1.574ProPhe: 1.574 ± 0.023
6.187ProGly: 6.187 ± 0.054
1.15ProHis: 1.15 ± 0.02
1.825ProIle: 1.825 ± 0.026
1.004ProLys: 1.004 ± 0.023
5.139ProLeu: 5.139 ± 0.043
1.084ProMet: 1.084 ± 0.02
1.107ProAsn: 1.107 ± 0.019
4.546ProPro: 4.546 ± 0.069
1.583ProGln: 1.583 ± 0.028
4.155ProArg: 4.155 ± 0.05
3.484ProSer: 3.484 ± 0.042
3.83ProThr: 3.83 ± 0.042
5.411ProVal: 5.411 ± 0.047
0.997ProTrp: 0.997 ± 0.02
1.288ProTyr: 1.288 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
3.84GlnAla: 3.84 ± 0.043
0.171GlnCys: 0.171 ± 0.008
1.178GlnAsp: 1.178 ± 0.02
1.205GlnGlu: 1.205 ± 0.02
0.762GlnPhe: 0.762 ± 0.018
1.93GlnGly: 1.93 ± 0.031
0.621GlnHis: 0.621 ± 0.014
1.221GlnIle: 1.221 ± 0.023
0.45GlnLys: 0.45 ± 0.017
3.132GlnLeu: 3.132 ± 0.038
0.52GlnMet: 0.52 ± 0.015
0.468GlnAsn: 0.468 ± 0.014
1.96GlnPro: 1.96 ± 0.032
1.161GlnGln: 1.161 ± 0.029
2.661GlnArg: 2.661 ± 0.034
1.237GlnSer: 1.237 ± 0.023
1.46GlnThr: 1.46 ± 0.025
2.715GlnVal: 2.715 ± 0.034
0.513GlnTrp: 0.513 ± 0.015
0.588GlnTyr: 0.588 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
10.044ArgAla: 10.044 ± 0.075
0.744ArgCys: 0.744 ± 0.017
4.529ArgAsp: 4.529 ± 0.04
4.368ArgGlu: 4.368 ± 0.042
2.424ArgPhe: 2.424 ± 0.032
5.892ArgGly: 5.892 ± 0.047
2.087ArgHis: 2.087 ± 0.027
3.092ArgIle: 3.092 ± 0.039
1.382ArgLys: 1.382 ± 0.027
9.138ArgLeu: 9.138 ± 0.071
1.825ArgMet: 1.825 ± 0.024
1.374ArgAsn: 1.374 ± 0.025
5.297ArgPro: 5.297 ± 0.05
2.626ArgGln: 2.626 ± 0.031
8.561ArgArg: 8.561 ± 0.086
4.317ArgSer: 4.317 ± 0.039
4.752ArgThr: 4.752 ± 0.049
6.381ArgVal: 6.381 ± 0.049
1.679ArgTrp: 1.679 ± 0.025
2.059ArgTyr: 2.059 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
6.685SerAla: 6.685 ± 0.045
0.44SerCys: 0.44 ± 0.015
2.572SerAsp: 2.572 ± 0.031
2.091SerGlu: 2.091 ± 0.029
1.513SerPhe: 1.513 ± 0.026
5.894SerGly: 5.894 ± 0.057
0.939SerHis: 0.939 ± 0.02
1.714SerIle: 1.714 ± 0.024
0.825SerLys: 0.825 ± 0.021
4.59SerLeu: 4.59 ± 0.043
1.071SerMet: 1.071 ± 0.021
0.985SerAsn: 0.985 ± 0.026
3.475SerPro: 3.475 ± 0.044
1.305SerGln: 1.305 ± 0.025
4.12SerArg: 4.12 ± 0.041
2.988SerSer: 2.988 ± 0.045
3.483SerThr: 3.483 ± 0.042
4.192SerVal: 4.192 ± 0.038
1.021SerTrp: 1.021 ± 0.019
1.223SerTyr: 1.223 ± 0.022
0.0SerXaa: 0.0 ± 0.0
Thr
8.407ThrAla: 8.407 ± 0.057
0.469ThrCys: 0.469 ± 0.015
3.332ThrAsp: 3.332 ± 0.037
2.769ThrGlu: 2.769 ± 0.032
1.762ThrPhe: 1.762 ± 0.025
6.362ThrGly: 6.362 ± 0.058
1.091ThrHis: 1.091 ± 0.02
2.151ThrIle: 2.151 ± 0.035
1.046ThrLys: 1.046 ± 0.02
5.795ThrLeu: 5.795 ± 0.048
1.033ThrMet: 1.033 ± 0.021
1.224ThrAsn: 1.224 ± 0.024
4.189ThrPro: 4.189 ± 0.044
1.438ThrGln: 1.438 ± 0.025
4.152ThrArg: 4.152 ± 0.041
3.322ThrSer: 3.322 ± 0.042
3.968ThrThr: 3.968 ± 0.051
6.081ThrVal: 6.081 ± 0.056
1.009ThrTrp: 1.009 ± 0.022
1.356ThrTyr: 1.356 ± 0.024
0.0ThrXaa: 0.0 ± 0.0
Val
12.678ValAla: 12.678 ± 0.087
0.65ValCys: 0.65 ± 0.016
5.844ValAsp: 5.844 ± 0.05
4.946ValGlu: 4.946 ± 0.048
2.347ValPhe: 2.347 ± 0.03
7.13ValGly: 7.13 ± 0.055
1.801ValHis: 1.801 ± 0.028
2.957ValIle: 2.957 ± 0.039
1.468ValLys: 1.468 ± 0.027
9.314ValLeu: 9.314 ± 0.072
1.286ValMet: 1.286 ± 0.022
1.795ValAsn: 1.795 ± 0.028
5.248ValPro: 5.248 ± 0.049
2.043ValGln: 2.043 ± 0.027
7.084ValArg: 7.084 ± 0.052
4.468ValSer: 4.468 ± 0.047
5.872ValThr: 5.872 ± 0.054
8.68ValVal: 8.68 ± 0.07
1.154ValTrp: 1.154 ± 0.024
1.634ValTyr: 1.634 ± 0.024
0.0ValXaa: 0.0 ± 0.0
Trp
1.703TrpAla: 1.703 ± 0.022
0.182TrpCys: 0.182 ± 0.008
0.815TrpAsp: 0.815 ± 0.018
0.718TrpGlu: 0.718 ± 0.018
0.504TrpPhe: 0.504 ± 0.016
1.081TrpGly: 1.081 ± 0.019
0.406TrpHis: 0.406 ± 0.011
0.573TrpIle: 0.573 ± 0.015
0.263TrpLys: 0.263 ± 0.009
1.962TrpLeu: 1.962 ± 0.027
0.317TrpMet: 0.317 ± 0.011
0.386TrpAsn: 0.386 ± 0.015
1.024TrpPro: 1.024 ± 0.021
0.636TrpGln: 0.636 ± 0.016
1.691TrpArg: 1.691 ± 0.026
1.1TrpSer: 1.1 ± 0.023
1.101TrpThr: 1.101 ± 0.021
1.155TrpVal: 1.155 ± 0.022
0.396TrpTrp: 0.396 ± 0.013
0.388TrpTyr: 0.388 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.749TyrAla: 2.749 ± 0.031
0.185TyrCys: 0.185 ± 0.007
1.404TyrAsp: 1.404 ± 0.032
1.156TyrGlu: 1.156 ± 0.021
0.643TyrPhe: 0.643 ± 0.017
2.176TyrGly: 2.176 ± 0.032
0.454TyrHis: 0.454 ± 0.013
0.523TyrIle: 0.523 ± 0.015
0.363TyrLys: 0.363 ± 0.012
2.27TyrLeu: 2.27 ± 0.031
0.245TyrMet: 0.245 ± 0.009
0.463TyrAsn: 0.463 ± 0.014
1.227TyrPro: 1.227 ± 0.023
0.682TyrGln: 0.682 ± 0.018
1.925TyrArg: 1.925 ± 0.029
0.986TyrSer: 0.986 ± 0.02
1.308TyrThr: 1.308 ± 0.024
1.772TyrVal: 1.772 ± 0.025
0.384TyrTrp: 0.384 ± 0.011
0.473TyrTyr: 0.473 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9064 proteins (2839989 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski