Amino acid dipepetide frequency for Hubei permutotetra-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.706AlaAla: 3.706 ± 1.047
0.618AlaCys: 0.618 ± 0.949
3.088AlaAsp: 3.088 ± 1.365
4.941AlaGlu: 4.941 ± 0.861
3.706AlaPhe: 3.706 ± 1.047
3.706AlaGly: 3.706 ± 1.078
0.618AlaHis: 0.618 ± 0.313
1.235AlaIle: 1.235 ± 0.625
4.324AlaLys: 4.324 ± 1.31
4.941AlaLeu: 4.941 ± 1.624
0.618AlaMet: 0.618 ± 1.715
3.088AlaAsn: 3.088 ± 1.368
4.324AlaPro: 4.324 ± 2.189
1.235AlaGln: 1.235 ± 0.625
6.794AlaArg: 6.794 ± 0.754
3.706AlaSer: 3.706 ± 1.355
4.324AlaThr: 4.324 ± 2.117
6.794AlaVal: 6.794 ± 2.513
2.471AlaTrp: 2.471 ± 1.251
3.088AlaTyr: 3.088 ± 0.848
0.0AlaXaa: 0.0 ± 0.0
Cys
0.618CysAla: 0.618 ± 0.313
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.235CysGlu: 1.235 ± 0.75
0.0CysPhe: 0.0 ± 0.0
1.235CysGly: 1.235 ± 0.757
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.618CysLeu: 0.618 ± 0.313
0.0CysMet: 0.0 ± 0.0
0.618CysAsn: 0.618 ± 0.965
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.618CysArg: 0.618 ± 0.313
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.235CysVal: 1.235 ± 0.757
0.0CysTrp: 0.0 ± 0.0
0.618CysTyr: 0.618 ± 0.965
0.0CysXaa: 0.0 ± 0.0
Asp
4.324AspAla: 4.324 ± 2.288
0.0AspCys: 0.0 ± 0.0
4.941AspAsp: 4.941 ± 1.624
3.706AspGlu: 3.706 ± 1.047
2.471AspPhe: 2.471 ± 0.687
3.706AspGly: 3.706 ± 0.176
1.235AspHis: 1.235 ± 1.427
2.471AspIle: 2.471 ± 1.251
1.853AspLys: 1.853 ± 1.707
8.647AspLeu: 8.647 ± 0.992
0.618AspMet: 0.618 ± 0.965
0.618AspAsn: 0.618 ± 0.313
3.706AspPro: 3.706 ± 1.078
1.235AspGln: 1.235 ± 0.757
3.706AspArg: 3.706 ± 1.876
4.324AspSer: 4.324 ± 1.343
1.235AspThr: 1.235 ± 0.75
3.088AspVal: 3.088 ± 0.848
1.235AspTrp: 1.235 ± 0.75
0.618AspTyr: 0.618 ± 0.313
0.0AspXaa: 0.0 ± 0.0
Glu
6.177GluAla: 6.177 ± 2.212
1.235GluCys: 1.235 ± 0.625
1.853GluAsp: 1.853 ± 0.647
4.941GluGlu: 4.941 ± 1.373
3.706GluPhe: 3.706 ± 0.176
3.088GluGly: 3.088 ± 0.489
0.618GluHis: 0.618 ± 0.313
1.853GluIle: 1.853 ± 0.641
4.324GluLys: 4.324 ± 1.098
5.559GluLeu: 5.559 ± 0.762
1.853GluMet: 1.853 ± 0.704
4.324GluAsn: 4.324 ± 1.343
6.177GluPro: 6.177 ± 1.696
2.471GluGln: 2.471 ± 1.251
3.706GluArg: 3.706 ± 1.078
4.324GluSer: 4.324 ± 1.27
2.471GluThr: 2.471 ± 1.251
4.324GluVal: 4.324 ± 1.343
3.088GluTrp: 3.088 ± 0.848
1.853GluTyr: 1.853 ± 0.647
0.0GluXaa: 0.0 ± 0.0
Phe
3.088PheAla: 3.088 ± 1.365
0.618PheCys: 0.618 ± 0.965
3.706PheAsp: 3.706 ± 1.355
1.853PheGlu: 1.853 ± 0.647
1.853PhePhe: 1.853 ± 0.938
1.235PheGly: 1.235 ± 0.75
1.235PheHis: 1.235 ± 0.625
0.0PheIle: 0.0 ± 0.0
1.853PheLys: 1.853 ± 0.938
4.941PheLeu: 4.941 ± 1.591
0.618PheMet: 0.618 ± 0.313
1.235PheAsn: 1.235 ± 1.427
0.618PhePro: 0.618 ± 0.313
1.853PheGln: 1.853 ± 0.647
2.471PheArg: 2.471 ± 0.667
4.941PheSer: 4.941 ± 1.591
3.706PheThr: 3.706 ± 3.363
4.324PheVal: 4.324 ± 2.106
1.853PheTrp: 1.853 ± 1.114
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.941GlyAla: 4.941 ± 0.861
0.0GlyCys: 0.0 ± 0.0
3.706GlyAsp: 3.706 ± 1.282
4.941GlyGlu: 4.941 ± 0.45
4.941GlyPhe: 4.941 ± 1.373
9.265GlyGly: 9.265 ± 5.137
0.618GlyHis: 0.618 ± 0.313
1.853GlyIle: 1.853 ± 1.707
3.706GlyLys: 3.706 ± 1.047
5.559GlyLeu: 5.559 ± 1.883
1.235GlyMet: 1.235 ± 0.757
2.471GlyAsn: 2.471 ± 3.146
4.941GlyPro: 4.941 ± 1.603
1.853GlyGln: 1.853 ± 0.938
7.412GlyArg: 7.412 ± 2.365
3.706GlySer: 3.706 ± 1.282
4.324GlyThr: 4.324 ± 1.27
4.941GlyVal: 4.941 ± 0.859
1.235GlyTrp: 1.235 ± 0.75
1.853GlyTyr: 1.853 ± 1.682
0.0GlyXaa: 0.0 ± 0.0
His
1.235HisAla: 1.235 ± 0.625
0.0HisCys: 0.0 ± 0.0
1.235HisAsp: 1.235 ± 0.757
0.618HisGlu: 0.618 ± 0.313
0.618HisPhe: 0.618 ± 0.949
2.471HisGly: 2.471 ± 1.251
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.853HisLeu: 1.853 ± 0.647
0.618HisMet: 0.618 ± 0.313
0.0HisAsn: 0.0 ± 0.0
2.471HisPro: 2.471 ± 0.802
1.235HisGln: 1.235 ± 0.75
0.0HisArg: 0.0 ± 0.0
3.706HisSer: 3.706 ± 1.078
0.618HisThr: 0.618 ± 0.949
1.853HisVal: 1.853 ± 0.647
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.853IleAla: 1.853 ± 0.641
0.0IleCys: 0.0 ± 0.0
1.853IleAsp: 1.853 ± 0.938
2.471IleGlu: 2.471 ± 1.251
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
1.853IleHis: 1.853 ± 0.938
2.471IleIle: 2.471 ± 0.667
1.853IleLys: 1.853 ± 0.641
2.471IleLeu: 2.471 ± 0.687
0.618IleMet: 0.618 ± 0.313
0.0IleAsn: 0.0 ± 0.0
3.088IlePro: 3.088 ± 2.825
0.618IleGln: 0.618 ± 0.313
1.853IleArg: 1.853 ± 1.114
7.412IleSer: 7.412 ± 3.483
0.618IleThr: 0.618 ± 0.313
2.471IleVal: 2.471 ± 0.802
0.0IleTrp: 0.0 ± 0.0
1.235IleTyr: 1.235 ± 0.625
0.0IleXaa: 0.0 ± 0.0
Lys
3.088LysAla: 3.088 ± 1.564
0.0LysCys: 0.0 ± 0.0
2.471LysAsp: 2.471 ± 0.667
1.235LysGlu: 1.235 ± 0.625
3.088LysPhe: 3.088 ± 0.489
1.235LysGly: 1.235 ± 0.757
0.618LysHis: 0.618 ± 0.313
3.088LysIle: 3.088 ± 1.564
2.471LysLys: 2.471 ± 0.687
3.088LysLeu: 3.088 ± 0.82
1.853LysMet: 1.853 ± 0.938
1.853LysAsn: 1.853 ± 0.641
4.941LysPro: 4.941 ± 2.502
3.706LysGln: 3.706 ± 1.876
4.324LysArg: 4.324 ± 1.091
2.471LysSer: 2.471 ± 1.515
3.088LysThr: 3.088 ± 0.848
4.324LysVal: 4.324 ± 1.091
0.0LysTrp: 0.0 ± 0.0
0.618LysTyr: 0.618 ± 0.949
0.0LysXaa: 0.0 ± 0.0
Leu
7.412LeuAla: 7.412 ± 1.7
0.618LeuCys: 0.618 ± 0.313
6.794LeuAsp: 6.794 ± 3.598
7.412LeuGlu: 7.412 ± 2.157
4.941LeuPhe: 4.941 ± 0.861
4.324LeuGly: 4.324 ± 2.189
2.471LeuHis: 2.471 ± 0.687
3.088LeuIle: 3.088 ± 1.564
2.471LeuLys: 2.471 ± 0.802
4.941LeuLeu: 4.941 ± 3.23
1.853LeuMet: 1.853 ± 0.641
1.853LeuAsn: 1.853 ± 1.114
4.941LeuPro: 4.941 ± 1.624
3.706LeuGln: 3.706 ± 2.551
5.559LeuArg: 5.559 ± 1.915
5.559LeuSer: 5.559 ± 0.699
6.177LeuThr: 6.177 ± 2.11
8.03LeuVal: 8.03 ± 2.191
2.471LeuTrp: 2.471 ± 0.687
2.471LeuTyr: 2.471 ± 1.251
0.0LeuXaa: 0.0 ± 0.0
Met
1.235MetAla: 1.235 ± 0.625
0.0MetCys: 0.0 ± 0.0
1.235MetAsp: 1.235 ± 0.625
0.618MetGlu: 0.618 ± 0.965
0.0MetPhe: 0.0 ± 0.0
1.235MetGly: 1.235 ± 1.931
0.0MetHis: 0.0 ± 0.0
0.618MetIle: 0.618 ± 0.313
1.235MetLys: 1.235 ± 0.625
3.088MetLeu: 3.088 ± 0.82
2.471MetMet: 2.471 ± 1.251
1.235MetAsn: 1.235 ± 0.75
1.235MetPro: 1.235 ± 0.757
0.0MetGln: 0.0 ± 0.0
1.235MetArg: 1.235 ± 0.625
2.471MetSer: 2.471 ± 0.802
2.471MetThr: 2.471 ± 0.667
2.471MetVal: 2.471 ± 1.499
0.0MetTrp: 0.0 ± 0.0
0.618MetTyr: 0.618 ± 0.313
0.0MetXaa: 0.0 ± 0.0
Asn
0.618AsnAla: 0.618 ± 0.313
0.0AsnCys: 0.0 ± 0.0
0.618AsnAsp: 0.618 ± 0.965
2.471AsnGlu: 2.471 ± 0.667
0.618AsnPhe: 0.618 ± 0.313
3.706AsnGly: 3.706 ± 4.595
0.0AsnHis: 0.0 ± 0.0
1.853AsnIle: 1.853 ± 1.682
2.471AsnLys: 2.471 ± 0.687
4.324AsnLeu: 4.324 ± 3.485
0.618AsnMet: 0.618 ± 0.313
0.0AsnAsn: 0.0 ± 0.0
4.324AsnPro: 4.324 ± 1.098
1.853AsnGln: 1.853 ± 0.938
0.618AsnArg: 0.618 ± 0.313
2.471AsnSer: 2.471 ± 1.926
0.0AsnThr: 0.0 ± 0.0
3.088AsnVal: 3.088 ± 0.82
0.0AsnTrp: 0.0 ± 0.0
0.618AsnTyr: 0.618 ± 0.313
0.0AsnXaa: 0.0 ± 0.0
Pro
4.324ProAla: 4.324 ± 1.916
1.235ProCys: 1.235 ± 0.757
3.706ProAsp: 3.706 ± 1.047
6.177ProGlu: 6.177 ± 3.127
4.324ProPhe: 4.324 ± 1.31
3.088ProGly: 3.088 ± 1.368
1.853ProHis: 1.853 ± 1.682
1.235ProIle: 1.235 ± 0.625
7.412ProLys: 7.412 ± 2.157
4.941ProLeu: 4.941 ± 1.603
1.853ProMet: 1.853 ± 0.938
0.618ProAsn: 0.618 ± 0.949
3.706ProPro: 3.706 ± 1.078
1.235ProGln: 1.235 ± 0.625
4.324ProArg: 4.324 ± 1.27
4.941ProSer: 4.941 ± 4.735
4.324ProThr: 4.324 ± 2.106
6.794ProVal: 6.794 ± 0.754
1.853ProTrp: 1.853 ± 0.647
2.471ProTyr: 2.471 ± 1.251
0.0ProXaa: 0.0 ± 0.0
Gln
2.471GlnAla: 2.471 ± 1.251
0.0GlnCys: 0.0 ± 0.0
0.618GlnAsp: 0.618 ± 0.313
1.853GlnGlu: 1.853 ± 0.938
1.235GlnPhe: 1.235 ± 1.427
1.853GlnGly: 1.853 ± 0.647
1.235GlnHis: 1.235 ± 0.75
1.853GlnIle: 1.853 ± 0.938
2.471GlnLys: 2.471 ± 1.251
3.706GlnLeu: 3.706 ± 1.876
0.618GlnMet: 0.618 ± 0.313
1.235GlnAsn: 1.235 ± 0.75
3.088GlnPro: 3.088 ± 1.365
1.853GlnGln: 1.853 ± 0.938
3.706GlnArg: 3.706 ± 1.282
1.235GlnSer: 1.235 ± 0.757
0.0GlnThr: 0.0 ± 0.0
1.853GlnVal: 1.853 ± 0.647
0.618GlnTrp: 0.618 ± 0.313
1.853GlnTyr: 1.853 ± 0.647
0.0GlnXaa: 0.0 ± 0.0
Arg
5.559ArgAla: 5.559 ± 1.462
0.0ArgCys: 0.0 ± 0.0
3.706ArgAsp: 3.706 ± 1.282
6.794ArgGlu: 6.794 ± 1.388
0.0ArgPhe: 0.0 ± 0.0
10.5ArgGly: 10.5 ± 1.52
1.235ArgHis: 1.235 ± 0.75
3.706ArgIle: 3.706 ± 1.368
1.235ArgLys: 1.235 ± 0.625
7.412ArgLeu: 7.412 ± 0.906
1.853ArgMet: 1.853 ± 0.647
1.853ArgAsn: 1.853 ± 0.938
6.177ArgPro: 6.177 ± 0.978
2.471ArgGln: 2.471 ± 0.687
12.353ArgArg: 12.353 ± 5.473
4.324ArgSer: 4.324 ± 0.137
4.324ArgThr: 4.324 ± 1.31
5.559ArgVal: 5.559 ± 1.883
3.088ArgTrp: 3.088 ± 1.368
2.471ArgTyr: 2.471 ± 0.687
0.0ArgXaa: 0.0 ± 0.0
Ser
5.559SerAla: 5.559 ± 1.915
1.235SerCys: 1.235 ± 1.931
1.853SerAsp: 1.853 ± 0.647
5.559SerGlu: 5.559 ± 0.682
1.235SerPhe: 1.235 ± 0.75
7.412SerGly: 7.412 ± 1.7
1.235SerHis: 1.235 ± 0.75
2.471SerIle: 2.471 ± 1.945
3.088SerLys: 3.088 ± 0.82
7.412SerLeu: 7.412 ± 3.487
1.853SerMet: 1.853 ± 1.358
2.471SerAsn: 2.471 ± 1.515
3.706SerPro: 3.706 ± 1.368
3.706SerGln: 3.706 ± 1.078
8.03SerArg: 8.03 ± 2.191
4.941SerSer: 4.941 ± 3.275
3.706SerThr: 3.706 ± 1.368
4.324SerVal: 4.324 ± 1.098
1.235SerTrp: 1.235 ± 0.757
1.853SerTyr: 1.853 ± 1.707
0.0SerXaa: 0.0 ± 0.0
Thr
3.088ThrAla: 3.088 ± 0.82
0.0ThrCys: 0.0 ± 0.0
1.853ThrAsp: 1.853 ± 0.641
1.853ThrGlu: 1.853 ± 0.938
3.706ThrPhe: 3.706 ± 3.363
5.559ThrGly: 5.559 ± 1.822
1.235ThrHis: 1.235 ± 0.757
0.618ThrIle: 0.618 ± 0.965
2.471ThrLys: 2.471 ± 1.499
3.088ThrLeu: 3.088 ± 1.365
0.0ThrMet: 0.0 ± 0.0
1.853ThrAsn: 1.853 ± 0.641
5.559ThrPro: 5.559 ± 1.29
1.235ThrGln: 1.235 ± 0.625
5.559ThrArg: 5.559 ± 1.462
4.941ThrSer: 4.941 ± 1.603
3.706ThrThr: 3.706 ± 1.047
4.941ThrVal: 4.941 ± 1.333
1.853ThrTrp: 1.853 ± 0.938
0.618ThrTyr: 0.618 ± 0.313
0.0ThrXaa: 0.0 ± 0.0
Val
5.559ValAla: 5.559 ± 1.924
0.0ValCys: 0.0 ± 0.0
8.03ValAsp: 8.03 ± 2.415
6.794ValGlu: 6.794 ± 1.443
2.471ValPhe: 2.471 ± 1.926
5.559ValGly: 5.559 ± 2.395
1.853ValHis: 1.853 ± 0.938
1.853ValIle: 1.853 ± 0.641
2.471ValLys: 2.471 ± 1.251
6.794ValLeu: 6.794 ± 0.754
1.853ValMet: 1.853 ± 0.641
4.324ValAsn: 4.324 ± 1.297
4.941ValPro: 4.941 ± 1.333
1.853ValGln: 1.853 ± 0.647
6.794ValArg: 6.794 ± 0.754
5.559ValSer: 5.559 ± 1.942
5.559ValThr: 5.559 ± 1.924
9.265ValVal: 9.265 ± 2.653
0.618ValTrp: 0.618 ± 0.965
2.471ValTyr: 2.471 ± 1.251
0.0ValXaa: 0.0 ± 0.0
Trp
1.853TrpAla: 1.853 ± 0.938
0.618TrpCys: 0.618 ± 0.313
0.0TrpAsp: 0.0 ± 0.0
1.853TrpGlu: 1.853 ± 0.647
0.618TrpPhe: 0.618 ± 0.313
1.235TrpGly: 1.235 ± 0.75
0.618TrpHis: 0.618 ± 0.313
1.235TrpIle: 1.235 ± 0.757
1.853TrpLys: 1.853 ± 0.938
0.618TrpLeu: 0.618 ± 0.313
0.618TrpMet: 0.618 ± 0.949
0.618TrpAsn: 0.618 ± 0.949
0.618TrpPro: 0.618 ± 0.313
0.618TrpGln: 0.618 ± 0.965
3.088TrpArg: 3.088 ± 0.489
0.0TrpSer: 0.0 ± 0.0
1.853TrpThr: 1.853 ± 0.938
3.088TrpVal: 3.088 ± 0.489
0.0TrpTrp: 0.0 ± 0.0
1.235TrpTyr: 1.235 ± 0.757
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.235TyrAla: 1.235 ± 0.75
0.618TyrCys: 0.618 ± 0.313
2.471TyrAsp: 2.471 ± 0.687
0.618TyrGlu: 0.618 ± 0.313
2.471TyrPhe: 2.471 ± 1.251
3.088TyrGly: 3.088 ± 0.82
0.0TyrHis: 0.0 ± 0.0
1.235TyrIle: 1.235 ± 1.898
0.0TyrLys: 0.0 ± 0.0
3.088TyrLeu: 3.088 ± 0.848
1.235TyrMet: 1.235 ± 0.625
0.0TyrAsn: 0.0 ± 0.0
1.853TyrPro: 1.853 ± 0.641
0.618TyrGln: 0.618 ± 0.965
2.471TyrArg: 2.471 ± 1.251
1.853TyrSer: 1.853 ± 0.647
1.235TyrThr: 1.235 ± 0.757
1.853TyrVal: 1.853 ± 0.647
0.618TyrTrp: 0.618 ± 0.313
0.618TyrTyr: 0.618 ± 0.313
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1620 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski