Amino acid dipepetide frequency for Fragaria chiloensis cryptic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.973AlaAla: 5.973 ± 0.157
1.706AlaCys: 1.706 ± 0.906
3.413AlaAsp: 3.413 ± 1.334
7.679AlaGlu: 7.679 ± 1.46
6.826AlaPhe: 6.826 ± 1.614
1.706AlaGly: 1.706 ± 1.312
2.56AlaHis: 2.56 ± 1.031
7.679AlaIle: 7.679 ± 2.023
4.266AlaLys: 4.266 ± 1.155
4.266AlaLeu: 4.266 ± 1.155
2.56AlaMet: 2.56 ± 1.184
1.706AlaAsn: 1.706 ± 0.906
3.413AlaPro: 3.413 ± 0.92
5.119AlaGln: 5.119 ± 2.717
5.973AlaArg: 5.973 ± 1.368
2.56AlaSer: 2.56 ± 1.318
6.826AlaThr: 6.826 ± 2.654
5.119AlaVal: 5.119 ± 0.499
3.413AlaTrp: 3.413 ± 0.407
0.853AlaTyr: 0.853 ± 0.764
0.0AlaXaa: 0.0 ± 0.0
Cys
1.706CysAla: 1.706 ± 0.707
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.853CysPhe: 0.853 ± 0.656
0.0CysGly: 0.0 ± 0.0
1.706CysHis: 1.706 ± 0.707
0.853CysIle: 0.853 ± 0.764
0.853CysLys: 0.853 ± 0.764
2.56CysLeu: 2.56 ± 0.25
0.853CysMet: 0.853 ± 0.764
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.853CysGln: 0.853 ± 0.656
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.853CysThr: 0.853 ± 0.764
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.679AspAla: 7.679 ± 0.786
0.0AspCys: 0.0 ± 0.0
3.413AspAsp: 3.413 ± 0.92
4.266AspGlu: 4.266 ± 1.823
2.56AspPhe: 2.56 ± 1.561
1.706AspGly: 1.706 ± 0.667
0.853AspHis: 0.853 ± 0.764
3.413AspIle: 3.413 ± 0.92
1.706AspLys: 1.706 ± 0.707
4.266AspLeu: 4.266 ± 2.301
0.0AspMet: 0.0 ± 0.0
3.413AspAsn: 3.413 ± 1.594
2.56AspPro: 2.56 ± 1.969
0.853AspGln: 0.853 ± 0.656
4.266AspArg: 4.266 ± 0.657
5.973AspSer: 5.973 ± 1.482
0.0AspThr: 0.0 ± 0.0
0.853AspVal: 0.853 ± 0.764
0.853AspTrp: 0.853 ± 0.656
4.266AspTyr: 4.266 ± 0.657
0.0AspXaa: 0.0 ± 0.0
Glu
4.266GluAla: 4.266 ± 1.972
0.853GluCys: 0.853 ± 0.764
3.413GluAsp: 3.413 ± 0.407
4.266GluGlu: 4.266 ± 0.657
1.706GluPhe: 1.706 ± 0.906
3.413GluGly: 3.413 ± 0.407
2.56GluHis: 2.56 ± 1.969
6.826GluIle: 6.826 ± 1.839
2.56GluLys: 2.56 ± 1.031
6.826GluLeu: 6.826 ± 1.614
0.0GluMet: 0.0 ± 0.531
0.853GluAsn: 0.853 ± 0.656
3.413GluPro: 3.413 ± 1.002
2.56GluGln: 2.56 ± 1.356
3.413GluArg: 3.413 ± 1.002
5.973GluSer: 5.973 ± 0.157
0.853GluThr: 0.853 ± 0.83
2.56GluVal: 2.56 ± 2.491
2.56GluTrp: 2.56 ± 1.318
2.56GluTyr: 2.56 ± 1.13
0.0GluXaa: 0.0 ± 0.0
Phe
5.973PheAla: 5.973 ± 2.235
0.0PheCys: 0.0 ± 0.0
2.56PheAsp: 2.56 ± 1.031
3.413PheGlu: 3.413 ± 2.147
0.853PhePhe: 0.853 ± 0.656
1.706PheGly: 1.706 ± 1.661
1.706PheHis: 1.706 ± 0.667
5.119PheIle: 5.119 ± 1.719
0.853PheLys: 0.853 ± 0.83
4.266PheLeu: 4.266 ± 1.155
0.0PheMet: 0.0 ± 0.0
3.413PheAsn: 3.413 ± 1.811
2.56PhePro: 2.56 ± 1.031
0.853PheGln: 0.853 ± 0.83
4.266PheArg: 4.266 ± 1.768
0.853PheSer: 0.853 ± 0.656
5.119PheThr: 5.119 ± 1.719
0.853PheVal: 0.853 ± 0.656
0.0PheTrp: 0.0 ± 0.0
1.706PheTyr: 1.706 ± 0.707
0.0PheXaa: 0.0 ± 0.0
Gly
4.266GlyAla: 4.266 ± 1.823
0.0GlyCys: 0.0 ± 0.0
1.706GlyAsp: 1.706 ± 0.707
1.706GlyGlu: 1.706 ± 1.312
1.706GlyPhe: 1.706 ± 0.707
0.0GlyGly: 0.0 ± 0.0
2.56GlyHis: 2.56 ± 1.561
5.973GlyIle: 5.973 ± 1.301
1.706GlyLys: 1.706 ± 1.312
4.266GlyLeu: 4.266 ± 0.657
0.853GlyMet: 0.853 ± 0.83
0.853GlyAsn: 0.853 ± 0.83
1.706GlyPro: 1.706 ± 0.707
0.0GlyGln: 0.0 ± 0.0
1.706GlyArg: 1.706 ± 0.707
3.413GlySer: 3.413 ± 1.334
4.266GlyThr: 4.266 ± 2.865
1.706GlyVal: 1.706 ± 1.312
0.853GlyTrp: 0.853 ± 0.656
3.413GlyTyr: 3.413 ± 1.334
0.0GlyXaa: 0.0 ± 0.0
His
2.56HisAla: 2.56 ± 0.25
0.853HisCys: 0.853 ± 0.656
1.706HisAsp: 1.706 ± 0.707
0.853HisGlu: 0.853 ± 0.656
3.413HisPhe: 3.413 ± 1.334
3.413HisGly: 3.413 ± 2.034
0.0HisHis: 0.0 ± 0.0
2.56HisIle: 2.56 ± 1.13
0.0HisLys: 0.0 ± 0.0
2.56HisLeu: 2.56 ± 2.491
0.853HisMet: 0.853 ± 0.83
2.56HisAsn: 2.56 ± 0.25
0.0HisPro: 0.0 ± 0.0
0.853HisGln: 0.853 ± 0.656
2.56HisArg: 2.56 ± 1.13
0.853HisSer: 0.853 ± 0.656
0.853HisThr: 0.853 ± 0.83
1.706HisVal: 1.706 ± 0.707
0.0HisTrp: 0.0 ± 0.0
0.853HisTyr: 0.853 ± 0.656
0.0HisXaa: 0.0 ± 0.0
Ile
7.679IleAla: 7.679 ± 0.71
0.853IleCys: 0.853 ± 0.656
4.266IleAsp: 4.266 ± 1.063
6.826IleGlu: 6.826 ± 1.974
2.56IlePhe: 2.56 ± 1.356
4.266IleGly: 4.266 ± 0.657
4.266IleHis: 4.266 ± 1.672
3.413IleIle: 3.413 ± 1.708
0.853IleLys: 0.853 ± 0.656
3.413IleLeu: 3.413 ± 1.414
1.706IleMet: 1.706 ± 0.667
5.973IleAsn: 5.973 ± 1.11
6.826IlePro: 6.826 ± 0.703
4.266IleGln: 4.266 ± 0.657
3.413IleArg: 3.413 ± 1.708
1.706IleSer: 1.706 ± 0.906
1.706IleThr: 1.706 ± 0.906
3.413IleVal: 3.413 ± 0.407
0.853IleTrp: 0.853 ± 0.656
2.56IleTyr: 2.56 ± 1.031
0.0IleXaa: 0.0 ± 0.0
Lys
2.56LysAla: 2.56 ± 1.031
0.0LysCys: 0.0 ± 0.0
1.706LysAsp: 1.706 ± 1.527
1.706LysGlu: 1.706 ± 0.906
1.706LysPhe: 1.706 ± 0.667
1.706LysGly: 1.706 ± 0.906
0.0LysHis: 0.0 ± 0.0
3.413LysIle: 3.413 ± 1.708
2.56LysLys: 2.56 ± 1.455
4.266LysLeu: 4.266 ± 0.657
0.0LysMet: 0.0 ± 0.0
0.853LysAsn: 0.853 ± 0.764
0.0LysPro: 0.0 ± 0.0
0.853LysGln: 0.853 ± 0.83
2.56LysArg: 2.56 ± 0.25
4.266LysSer: 4.266 ± 1.063
4.266LysThr: 4.266 ± 1.969
5.973LysVal: 5.973 ± 1.482
0.853LysTrp: 0.853 ± 0.656
0.853LysTyr: 0.853 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
8.532LeuAla: 8.532 ± 3.344
2.56LeuCys: 2.56 ± 1.13
3.413LeuAsp: 3.413 ± 0.407
5.973LeuGlu: 5.973 ± 2.821
5.119LeuPhe: 5.119 ± 0.849
5.119LeuGly: 5.119 ± 1.683
1.706LeuHis: 1.706 ± 0.667
2.56LeuIle: 2.56 ± 1.031
5.119LeuLys: 5.119 ± 1.368
7.679LeuLeu: 7.679 ± 1.47
0.0LeuMet: 0.0 ± 0.0
3.413LeuAsn: 3.413 ± 1.334
9.386LeuPro: 9.386 ± 3.531
4.266LeuGln: 4.266 ± 1.969
10.239LeuArg: 10.239 ± 0.643
5.119LeuSer: 5.119 ± 1.719
5.119LeuThr: 5.119 ± 2.65
2.56LeuVal: 2.56 ± 1.13
0.0LeuTrp: 0.0 ± 0.0
2.56LeuTyr: 2.56 ± 0.25
0.0LeuXaa: 0.0 ± 0.0
Met
3.413MetAla: 3.413 ± 1.811
0.853MetCys: 0.853 ± 0.764
2.56MetAsp: 2.56 ± 1.13
0.853MetGlu: 0.853 ± 0.656
1.706MetPhe: 1.706 ± 0.667
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.853MetIle: 0.853 ± 0.764
0.853MetLys: 0.853 ± 0.83
1.706MetLeu: 1.706 ± 0.707
0.853MetMet: 0.853 ± 0.764
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.853MetGln: 0.853 ± 0.656
0.853MetArg: 0.853 ± 0.83
0.853MetSer: 0.853 ± 0.656
1.706MetThr: 1.706 ± 1.527
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.853MetTyr: 0.853 ± 0.83
0.0MetXaa: 0.0 ± 0.0
Asn
3.413AsnAla: 3.413 ± 1.002
0.0AsnCys: 0.0 ± 0.0
3.413AsnAsp: 3.413 ± 1.002
0.0AsnGlu: 0.0 ± 0.0
2.56AsnPhe: 2.56 ± 1.031
1.706AsnGly: 1.706 ± 0.707
0.853AsnHis: 0.853 ± 0.656
4.266AsnIle: 4.266 ± 0.657
1.706AsnLys: 1.706 ± 0.707
3.413AsnLeu: 3.413 ± 1.002
0.853AsnMet: 0.853 ± 0.764
1.706AsnAsn: 1.706 ± 0.667
2.56AsnPro: 2.56 ± 1.561
0.853AsnGln: 0.853 ± 0.656
1.706AsnArg: 1.706 ± 1.527
2.56AsnSer: 2.56 ± 0.25
3.413AsnThr: 3.413 ± 0.92
5.119AsnVal: 5.119 ± 1.789
2.56AsnTrp: 2.56 ± 1.031
4.266AsnTyr: 4.266 ± 1.768
0.0AsnXaa: 0.0 ± 0.0
Pro
3.413ProAla: 3.413 ± 1.811
0.853ProCys: 0.853 ± 0.764
2.56ProAsp: 2.56 ± 1.356
4.266ProGlu: 4.266 ± 1.155
1.706ProPhe: 1.706 ± 0.906
0.0ProGly: 0.0 ± 0.0
0.853ProHis: 0.853 ± 0.83
2.56ProIle: 2.56 ± 1.13
1.706ProLys: 1.706 ± 0.667
9.386ProLeu: 9.386 ± 1.487
0.0ProMet: 0.0 ± 0.0
2.56ProAsn: 2.56 ± 0.25
3.413ProPro: 3.413 ± 2.14
1.706ProGln: 1.706 ± 0.707
4.266ProArg: 4.266 ± 0.66
2.56ProSer: 2.56 ± 1.031
8.532ProThr: 8.532 ± 2.31
5.119ProVal: 5.119 ± 3.122
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.706GlnAla: 1.706 ± 0.667
0.0GlnCys: 0.0 ± 0.0
4.266GlnAsp: 4.266 ± 1.972
0.853GlnGlu: 0.853 ± 0.656
0.853GlnPhe: 0.853 ± 0.656
1.706GlnGly: 1.706 ± 0.906
2.56GlnHis: 2.56 ± 1.031
0.853GlnIle: 0.853 ± 0.656
0.0GlnLys: 0.0 ± 0.0
5.973GlnLeu: 5.973 ± 2.258
1.706GlnMet: 1.706 ± 0.707
2.56GlnAsn: 2.56 ± 1.13
1.706GlnPro: 1.706 ± 0.667
1.706GlnGln: 1.706 ± 0.667
0.853GlnArg: 0.853 ± 0.83
5.973GlnSer: 5.973 ± 4.763
1.706GlnThr: 1.706 ± 0.667
1.706GlnVal: 1.706 ± 0.707
0.0GlnTrp: 0.0 ± 0.0
3.413GlnTyr: 3.413 ± 1.708
0.0GlnXaa: 0.0 ± 0.0
Arg
5.973ArgAla: 5.973 ± 1.11
0.853ArgCys: 0.853 ± 0.764
4.266ArgAsp: 4.266 ± 0.657
4.266ArgGlu: 4.266 ± 0.66
1.706ArgPhe: 1.706 ± 1.312
1.706ArgGly: 1.706 ± 1.312
0.0ArgHis: 0.0 ± 0.0
3.413ArgIle: 3.413 ± 0.407
5.973ArgLys: 5.973 ± 2.375
3.413ArgLeu: 3.413 ± 1.708
3.413ArgMet: 3.413 ± 1.414
3.413ArgAsn: 3.413 ± 1.414
2.56ArgPro: 2.56 ± 1.356
1.706ArgGln: 1.706 ± 1.661
4.266ArgArg: 4.266 ± 1.155
3.413ArgSer: 3.413 ± 1.414
5.973ArgThr: 5.973 ± 1.11
2.56ArgVal: 2.56 ± 1.13
0.0ArgTrp: 0.0 ± 0.0
5.119ArgTyr: 5.119 ± 0.499
0.0ArgXaa: 0.0 ± 0.0
Ser
3.413SerAla: 3.413 ± 0.407
0.853SerCys: 0.853 ± 0.656
3.413SerAsp: 3.413 ± 0.92
1.706SerGlu: 1.706 ± 0.667
2.56SerPhe: 2.56 ± 1.969
2.56SerGly: 2.56 ± 1.969
1.706SerHis: 1.706 ± 0.707
6.826SerIle: 6.826 ± 2.091
3.413SerLys: 3.413 ± 1.002
7.679SerLeu: 7.679 ± 1.96
2.56SerMet: 2.56 ± 1.561
3.413SerAsn: 3.413 ± 2.14
3.413SerPro: 3.413 ± 2.14
1.706SerGln: 1.706 ± 1.661
4.266SerArg: 4.266 ± 0.66
4.266SerSer: 4.266 ± 1.607
3.413SerThr: 3.413 ± 1.594
4.266SerVal: 4.266 ± 0.657
0.0SerTrp: 0.0 ± 0.0
3.413SerTyr: 3.413 ± 1.708
0.0SerXaa: 0.0 ± 0.0
Thr
4.266ThrAla: 4.266 ± 1.672
0.0ThrCys: 0.0 ± 0.0
2.56ThrAsp: 2.56 ± 1.561
6.826ThrGlu: 6.826 ± 3.962
3.413ThrPhe: 3.413 ± 2.33
1.706ThrGly: 1.706 ± 1.661
3.413ThrHis: 3.413 ± 0.92
5.119ThrIle: 5.119 ± 1.441
2.56ThrLys: 2.56 ± 2.491
6.826ThrLeu: 6.826 ± 0.813
0.0ThrMet: 0.0 ± 0.0
3.413ThrAsn: 3.413 ± 1.708
4.266ThrPro: 4.266 ± 1.823
6.826ThrGln: 6.826 ± 2.882
2.56ThrArg: 2.56 ± 1.13
2.56ThrSer: 2.56 ± 1.561
5.119ThrThr: 5.119 ± 2.121
1.706ThrVal: 1.706 ± 0.707
0.0ThrTrp: 0.0 ± 0.0
2.56ThrTyr: 2.56 ± 1.455
0.0ThrXaa: 0.0 ± 0.0
Val
3.413ValAla: 3.413 ± 2.14
0.853ValCys: 0.853 ± 0.764
1.706ValAsp: 1.706 ± 1.661
3.413ValGlu: 3.413 ± 1.708
1.706ValPhe: 1.706 ± 0.667
4.266ValGly: 4.266 ± 1.969
0.853ValHis: 0.853 ± 0.656
1.706ValIle: 1.706 ± 0.906
1.706ValLys: 1.706 ± 1.312
2.56ValLeu: 2.56 ± 0.25
0.853ValMet: 0.853 ± 0.648
3.413ValAsn: 3.413 ± 2.147
5.119ValPro: 5.119 ± 1.368
3.413ValGln: 3.413 ± 1.708
5.119ValArg: 5.119 ± 2.261
6.826ValSer: 6.826 ± 0.813
3.413ValThr: 3.413 ± 1.002
4.266ValVal: 4.266 ± 0.657
0.853ValTrp: 0.853 ± 0.656
2.56ValTyr: 2.56 ± 1.13
0.0ValXaa: 0.0 ± 0.0
Trp
0.853TrpAla: 0.853 ± 0.656
0.0TrpCys: 0.0 ± 0.0
0.853TrpAsp: 0.853 ± 0.656
0.853TrpGlu: 0.853 ± 0.656
0.0TrpPhe: 0.0 ± 0.0
0.853TrpGly: 0.853 ± 0.656
0.853TrpHis: 0.853 ± 0.656
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.853TrpLeu: 0.853 ± 0.83
0.0TrpMet: 0.0 ± 0.0
1.706TrpAsn: 1.706 ± 0.667
0.853TrpPro: 0.853 ± 0.764
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
3.413TrpSer: 3.413 ± 1.414
0.853TrpThr: 0.853 ± 0.656
0.853TrpVal: 0.853 ± 0.656
1.706TrpTrp: 1.706 ± 0.906
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.56TyrAla: 2.56 ± 1.561
0.0TyrCys: 0.0 ± 0.0
1.706TyrAsp: 1.706 ± 0.707
2.56TyrGlu: 2.56 ± 1.13
2.56TyrPhe: 2.56 ± 1.031
5.119TyrGly: 5.119 ± 0.849
0.0TyrHis: 0.0 ± 0.0
3.413TyrIle: 3.413 ± 0.92
1.706TyrLys: 1.706 ± 0.707
4.266TyrLeu: 4.266 ± 3.281
0.853TyrMet: 0.853 ± 0.656
1.706TyrAsn: 1.706 ± 0.906
1.706TyrPro: 1.706 ± 1.527
0.853TyrGln: 0.853 ± 0.764
1.706TyrArg: 1.706 ± 0.707
1.706TyrSer: 1.706 ± 0.707
1.706TyrThr: 1.706 ± 0.667
7.679TyrVal: 7.679 ± 2.599
0.0TyrTrp: 0.0 ± 0.0
1.706TyrTyr: 1.706 ± 0.707
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1173 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski