Amino acid dipepetide frequency for Hubei narna-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.415AlaAla: 6.415 ± 4.193
0.713AlaCys: 0.713 ± 0.358
2.851AlaAsp: 2.851 ± 2.276
2.851AlaGlu: 2.851 ± 1.433
1.426AlaPhe: 1.426 ± 1.756
0.713AlaGly: 0.713 ± 0.358
0.713AlaHis: 0.713 ± 0.358
5.702AlaIle: 5.702 ± 3.315
4.277AlaLys: 4.277 ± 0.913
3.564AlaLeu: 3.564 ± 1.918
2.851AlaMet: 2.851 ± 1.04
2.851AlaAsn: 2.851 ± 1.04
0.713AlaPro: 0.713 ± 0.878
2.851AlaGln: 2.851 ± 1.04
1.426AlaArg: 1.426 ± 0.52
3.564AlaSer: 3.564 ± 0.681
4.989AlaThr: 4.989 ± 0.035
2.138AlaVal: 2.138 ± 1.398
0.0AlaTrp: 0.0 ± 0.0
2.138AlaTyr: 2.138 ± 1.074
0.0AlaXaa: 0.0 ± 0.0
Cys
1.426CysAla: 1.426 ± 0.716
0.0CysCys: 0.0 ± 0.0
0.713CysAsp: 0.713 ± 0.358
2.138CysGlu: 2.138 ± 1.074
0.713CysPhe: 0.713 ± 0.358
0.713CysGly: 0.713 ± 0.878
0.0CysHis: 0.0 ± 0.0
0.713CysIle: 0.713 ± 0.878
0.0CysLys: 0.0 ± 0.0
2.851CysLeu: 2.851 ± 1.433
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.426CysPro: 1.426 ± 0.52
0.0CysGln: 0.0 ± 0.0
2.138CysArg: 2.138 ± 0.162
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.713CysTrp: 0.713 ± 0.358
0.713CysTyr: 0.713 ± 0.358
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
4.277AspAsp: 4.277 ± 0.913
4.277AspGlu: 4.277 ± 2.149
5.702AspPhe: 5.702 ± 2.079
2.138AspGly: 2.138 ± 1.074
0.0AspHis: 0.0 ± 0.0
2.138AspIle: 2.138 ± 1.398
2.851AspLys: 2.851 ± 1.433
2.851AspLeu: 2.851 ± 0.196
1.426AspMet: 1.426 ± 0.52
0.713AspAsn: 0.713 ± 0.358
4.277AspPro: 4.277 ± 1.559
1.426AspGln: 1.426 ± 0.716
1.426AspArg: 1.426 ± 0.52
4.989AspSer: 4.989 ± 2.507
2.851AspThr: 2.851 ± 0.196
6.415AspVal: 6.415 ± 0.751
0.713AspTrp: 0.713 ± 0.358
2.138AspTyr: 2.138 ± 0.162
0.0AspXaa: 0.0 ± 0.0
Glu
2.851GluAla: 2.851 ± 1.433
0.713GluCys: 0.713 ± 0.878
0.0GluAsp: 0.0 ± 0.0
1.426GluGlu: 1.426 ± 0.716
2.138GluPhe: 2.138 ± 1.074
2.851GluGly: 2.851 ± 1.04
2.851GluHis: 2.851 ± 1.433
3.564GluIle: 3.564 ± 1.791
4.989GluLys: 4.989 ± 2.507
5.702GluLeu: 5.702 ± 0.393
0.0GluMet: 0.0 ± 0.0
3.564GluAsn: 3.564 ± 0.681
4.277GluPro: 4.277 ± 2.149
4.277GluGln: 4.277 ± 0.323
1.426GluArg: 1.426 ± 0.716
3.564GluSer: 3.564 ± 0.555
1.426GluThr: 1.426 ± 0.52
6.415GluVal: 6.415 ± 3.223
0.713GluTrp: 0.713 ± 0.358
2.851GluTyr: 2.851 ± 1.433
0.0GluXaa: 0.0 ± 0.0
Phe
2.851PheAla: 2.851 ± 0.196
0.713PheCys: 0.713 ± 0.358
2.138PheAsp: 2.138 ± 0.162
6.415PheGlu: 6.415 ± 1.987
2.138PhePhe: 2.138 ± 0.162
2.138PheGly: 2.138 ± 0.162
2.138PheHis: 2.138 ± 1.074
2.138PheIle: 2.138 ± 1.074
3.564PheLys: 3.564 ± 0.555
6.415PheLeu: 6.415 ± 2.957
0.713PheMet: 0.713 ± 0.581
2.851PheAsn: 2.851 ± 1.433
2.851PhePro: 2.851 ± 0.196
2.851PheGln: 2.851 ± 1.04
4.989PheArg: 4.989 ± 2.507
2.851PheSer: 2.851 ± 0.196
4.277PheThr: 4.277 ± 1.559
4.989PheVal: 4.989 ± 2.507
1.426PheTrp: 1.426 ± 0.52
2.138PheTyr: 2.138 ± 0.162
0.0PheXaa: 0.0 ± 0.0
Gly
4.989GlyAla: 4.989 ± 2.437
1.426GlyCys: 1.426 ± 0.716
5.702GlyAsp: 5.702 ± 0.843
2.138GlyGlu: 2.138 ± 1.074
4.989GlyPhe: 4.989 ± 1.271
4.277GlyGly: 4.277 ± 1.559
0.713GlyHis: 0.713 ± 0.358
4.989GlyIle: 4.989 ± 1.201
1.426GlyLys: 1.426 ± 0.52
2.851GlyLeu: 2.851 ± 0.196
2.138GlyMet: 2.138 ± 1.398
4.989GlyAsn: 4.989 ± 0.035
0.713GlyPro: 0.713 ± 0.878
1.426GlyGln: 1.426 ± 0.716
1.426GlyArg: 1.426 ± 0.52
7.128GlySer: 7.128 ± 2.599
3.564GlyThr: 3.564 ± 1.918
2.138GlyVal: 2.138 ± 0.162
0.713GlyTrp: 0.713 ± 0.358
2.138GlyTyr: 2.138 ± 1.398
0.0GlyXaa: 0.0 ± 0.0
His
0.713HisAla: 0.713 ± 0.358
0.0HisCys: 0.0 ± 0.0
0.713HisAsp: 0.713 ± 0.358
0.713HisGlu: 0.713 ± 0.358
0.713HisPhe: 0.713 ± 0.358
1.426HisGly: 1.426 ± 0.52
0.0HisHis: 0.0 ± 0.0
2.138HisIle: 2.138 ± 1.074
2.851HisLys: 2.851 ± 1.433
2.851HisLeu: 2.851 ± 0.196
0.713HisMet: 0.713 ± 0.358
2.138HisAsn: 2.138 ± 1.074
0.0HisPro: 0.0 ± 0.0
0.713HisGln: 0.713 ± 0.878
0.713HisArg: 0.713 ± 0.878
2.138HisSer: 2.138 ± 0.162
0.713HisThr: 0.713 ± 0.358
2.138HisVal: 2.138 ± 0.162
0.0HisTrp: 0.0 ± 0.0
1.426HisTyr: 1.426 ± 0.716
0.0HisXaa: 0.0 ± 0.0
Ile
3.564IleAla: 3.564 ± 0.681
0.713IleCys: 0.713 ± 0.358
4.989IleAsp: 4.989 ± 1.201
3.564IleGlu: 3.564 ± 0.555
5.702IlePhe: 5.702 ± 0.393
4.989IleGly: 4.989 ± 1.201
1.426IleHis: 1.426 ± 0.716
2.138IleIle: 2.138 ± 0.162
5.702IleLys: 5.702 ± 0.393
8.553IleLeu: 8.553 ± 1.826
0.713IleMet: 0.713 ± 0.878
4.989IleAsn: 4.989 ± 1.271
5.702IlePro: 5.702 ± 0.393
0.713IleGln: 0.713 ± 0.878
2.138IleArg: 2.138 ± 1.074
5.702IleSer: 5.702 ± 0.843
6.415IleThr: 6.415 ± 0.485
0.713IleVal: 0.713 ± 0.878
1.426IleTrp: 1.426 ± 0.716
2.138IleTyr: 2.138 ± 1.398
0.0IleXaa: 0.0 ± 0.0
Lys
4.277LysAla: 4.277 ± 0.323
1.426LysCys: 1.426 ± 0.716
3.564LysAsp: 3.564 ± 0.555
3.564LysGlu: 3.564 ± 1.791
3.564LysPhe: 3.564 ± 1.791
2.138LysGly: 2.138 ± 1.074
2.138LysHis: 2.138 ± 0.162
7.128LysIle: 7.128 ± 1.109
4.989LysLys: 4.989 ± 1.271
10.691LysLeu: 10.691 ± 4.136
0.0LysMet: 0.0 ± 0.0
5.702LysAsn: 5.702 ± 0.393
2.138LysPro: 2.138 ± 1.074
1.426LysGln: 1.426 ± 0.52
3.564LysArg: 3.564 ± 1.791
3.564LysSer: 3.564 ± 0.681
4.989LysThr: 4.989 ± 0.035
7.128LysVal: 7.128 ± 0.127
0.713LysTrp: 0.713 ± 0.358
2.851LysTyr: 2.851 ± 1.433
0.0LysXaa: 0.0 ± 0.0
Leu
2.851LeuAla: 2.851 ± 0.196
3.564LeuCys: 3.564 ± 1.791
2.138LeuAsp: 2.138 ± 1.074
6.415LeuGlu: 6.415 ± 1.721
3.564LeuPhe: 3.564 ± 1.791
8.553LeuGly: 8.553 ± 0.647
2.851LeuHis: 2.851 ± 0.196
6.415LeuIle: 6.415 ± 0.751
9.266LeuLys: 9.266 ± 4.656
2.138LeuLeu: 2.138 ± 1.074
2.138LeuMet: 2.138 ± 0.978
8.553LeuAsn: 8.553 ± 0.647
7.128LeuPro: 7.128 ± 1.109
3.564LeuGln: 3.564 ± 1.791
1.426LeuArg: 1.426 ± 0.716
5.702LeuSer: 5.702 ± 0.393
5.702LeuThr: 5.702 ± 0.843
2.138LeuVal: 2.138 ± 0.162
0.0LeuTrp: 0.0 ± 0.0
3.564LeuTyr: 3.564 ± 1.791
0.0LeuXaa: 0.0 ± 0.0
Met
2.138MetAla: 2.138 ± 1.398
0.0MetCys: 0.0 ± 0.0
0.713MetAsp: 0.713 ± 0.358
0.713MetGlu: 0.713 ± 0.358
0.713MetPhe: 0.713 ± 0.878
1.426MetGly: 1.426 ± 0.716
0.0MetHis: 0.0 ± 0.0
0.713MetIle: 0.713 ± 0.358
2.138MetLys: 2.138 ± 0.162
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.138MetPro: 2.138 ± 2.634
0.713MetGln: 0.713 ± 0.878
0.713MetArg: 0.713 ± 0.358
0.713MetSer: 0.713 ± 0.358
1.426MetThr: 1.426 ± 0.52
0.713MetVal: 0.713 ± 0.358
0.0MetTrp: 0.0 ± 0.0
0.713MetTyr: 0.713 ± 0.878
0.0MetXaa: 0.0 ± 0.0
Asn
3.564AsnAla: 3.564 ± 3.154
0.713AsnCys: 0.713 ± 0.358
1.426AsnAsp: 1.426 ± 0.716
0.713AsnGlu: 0.713 ± 0.878
4.277AsnPhe: 4.277 ± 0.323
2.851AsnGly: 2.851 ± 1.433
1.426AsnHis: 1.426 ± 0.52
6.415AsnIle: 6.415 ± 0.751
7.84AsnLys: 7.84 ± 2.241
5.702AsnLeu: 5.702 ± 0.393
0.0AsnMet: 0.0 ± 0.0
2.851AsnAsn: 2.851 ± 3.512
2.138AsnPro: 2.138 ± 0.162
2.138AsnGln: 2.138 ± 2.634
2.851AsnArg: 2.851 ± 1.433
3.564AsnSer: 3.564 ± 0.555
1.426AsnThr: 1.426 ± 0.52
5.702AsnVal: 5.702 ± 4.552
0.713AsnTrp: 0.713 ± 0.358
3.564AsnTyr: 3.564 ± 0.555
0.0AsnXaa: 0.0 ± 0.0
Pro
2.138ProAla: 2.138 ± 1.074
0.0ProCys: 0.0 ± 0.0
3.564ProAsp: 3.564 ± 0.555
4.989ProGlu: 4.989 ± 1.271
2.851ProPhe: 2.851 ± 2.276
2.851ProGly: 2.851 ± 0.196
0.0ProHis: 0.0 ± 0.0
1.426ProIle: 1.426 ± 0.716
2.138ProLys: 2.138 ± 1.074
7.128ProLeu: 7.128 ± 1.109
0.713ProMet: 0.713 ± 0.358
2.851ProAsn: 2.851 ± 3.512
1.426ProPro: 1.426 ± 0.716
3.564ProGln: 3.564 ± 0.681
1.426ProArg: 1.426 ± 0.716
4.989ProSer: 4.989 ± 0.035
4.277ProThr: 4.277 ± 4.032
4.989ProVal: 4.989 ± 1.201
0.0ProTrp: 0.0 ± 0.0
2.138ProTyr: 2.138 ± 0.162
0.0ProXaa: 0.0 ± 0.0
Gln
3.564GlnAla: 3.564 ± 0.681
0.713GlnCys: 0.713 ± 0.358
2.138GlnAsp: 2.138 ± 0.162
0.713GlnGlu: 0.713 ± 0.358
1.426GlnPhe: 1.426 ± 0.716
1.426GlnGly: 1.426 ± 0.716
0.0GlnHis: 0.0 ± 0.0
2.851GlnIle: 2.851 ± 1.04
3.564GlnLys: 3.564 ± 0.681
3.564GlnLeu: 3.564 ± 0.555
0.713GlnMet: 0.713 ± 0.878
3.564GlnAsn: 3.564 ± 4.39
0.713GlnPro: 0.713 ± 0.878
0.713GlnGln: 0.713 ± 0.878
1.426GlnArg: 1.426 ± 0.52
2.138GlnSer: 2.138 ± 0.162
2.851GlnThr: 2.851 ± 0.196
4.277GlnVal: 4.277 ± 2.796
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.713ArgCys: 0.713 ± 0.878
3.564ArgAsp: 3.564 ± 0.555
4.277ArgGlu: 4.277 ± 2.149
4.277ArgPhe: 4.277 ± 2.149
4.277ArgGly: 4.277 ± 1.559
0.0ArgHis: 0.0 ± 0.0
2.138ArgIle: 2.138 ± 1.074
1.426ArgLys: 1.426 ± 0.52
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.0
1.426ArgAsn: 1.426 ± 0.716
2.138ArgPro: 2.138 ± 0.162
0.0ArgGln: 0.0 ± 0.0
2.138ArgArg: 2.138 ± 0.162
4.277ArgSer: 4.277 ± 2.149
1.426ArgThr: 1.426 ± 0.716
3.564ArgVal: 3.564 ± 0.681
0.0ArgTrp: 0.0 ± 0.0
2.851ArgTyr: 2.851 ± 0.196
0.0ArgXaa: 0.0 ± 0.0
Ser
3.564SerAla: 3.564 ± 1.918
0.713SerCys: 0.713 ± 0.878
2.851SerAsp: 2.851 ± 0.196
1.426SerGlu: 1.426 ± 0.716
4.989SerPhe: 4.989 ± 2.507
4.989SerGly: 4.989 ± 1.201
2.851SerHis: 2.851 ± 1.433
6.415SerIle: 6.415 ± 0.751
6.415SerLys: 6.415 ± 1.987
2.851SerLeu: 2.851 ± 0.196
0.713SerMet: 0.713 ± 0.358
6.415SerAsn: 6.415 ± 4.193
2.138SerPro: 2.138 ± 0.162
4.277SerGln: 4.277 ± 0.323
2.138SerArg: 2.138 ± 1.074
3.564SerSer: 3.564 ± 1.918
3.564SerThr: 3.564 ± 0.681
2.138SerVal: 2.138 ± 1.074
0.713SerTrp: 0.713 ± 0.878
3.564SerTyr: 3.564 ± 0.555
0.0SerXaa: 0.0 ± 0.0
Thr
3.564ThrAla: 3.564 ± 3.154
1.426ThrCys: 1.426 ± 0.52
4.989ThrAsp: 4.989 ± 2.507
2.138ThrGlu: 2.138 ± 1.074
2.138ThrPhe: 2.138 ± 1.074
4.277ThrGly: 4.277 ± 2.796
0.0ThrHis: 0.0 ± 0.0
4.989ThrIle: 4.989 ± 2.437
4.277ThrLys: 4.277 ± 0.913
4.277ThrLeu: 4.277 ± 0.323
0.713ThrMet: 0.713 ± 0.358
1.426ThrAsn: 1.426 ± 0.52
4.989ThrPro: 4.989 ± 2.437
2.851ThrGln: 2.851 ± 2.276
4.277ThrArg: 4.277 ± 1.559
1.426ThrSer: 1.426 ± 0.52
5.702ThrThr: 5.702 ± 2.079
2.138ThrVal: 2.138 ± 0.162
2.138ThrTrp: 2.138 ± 0.162
2.851ThrTyr: 2.851 ± 1.433
0.0ThrXaa: 0.0 ± 0.0
Val
2.138ValAla: 2.138 ± 1.398
0.713ValCys: 0.713 ± 0.358
2.138ValAsp: 2.138 ± 1.074
3.564ValGlu: 3.564 ± 1.918
3.564ValPhe: 3.564 ± 1.918
4.989ValGly: 4.989 ± 2.437
3.564ValHis: 3.564 ± 0.555
6.415ValIle: 6.415 ± 0.485
3.564ValLys: 3.564 ± 1.791
8.553ValLeu: 8.553 ± 1.826
0.713ValMet: 0.713 ± 0.878
1.426ValAsn: 1.426 ± 0.52
4.989ValPro: 4.989 ± 1.271
0.713ValGln: 0.713 ± 0.878
1.426ValArg: 1.426 ± 0.716
4.277ValSer: 4.277 ± 0.323
3.564ValThr: 3.564 ± 0.681
3.564ValVal: 3.564 ± 0.555
0.713ValTrp: 0.713 ± 0.358
3.564ValTyr: 3.564 ± 0.555
0.0ValXaa: 0.0 ± 0.0
Trp
0.713TrpAla: 0.713 ± 0.358
0.0TrpCys: 0.0 ± 0.0
1.426TrpAsp: 1.426 ± 0.52
0.713TrpGlu: 0.713 ± 0.358
2.138TrpPhe: 2.138 ± 1.074
1.426TrpGly: 1.426 ± 0.52
0.0TrpHis: 0.0 ± 0.0
0.713TrpIle: 0.713 ± 0.878
0.713TrpLys: 0.713 ± 0.358
0.713TrpLeu: 0.713 ± 0.358
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.713TrpThr: 0.713 ± 0.358
0.713TrpVal: 0.713 ± 0.358
0.0TrpTrp: 0.0 ± 0.0
0.713TrpTyr: 0.713 ± 0.358
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.426TyrAla: 1.426 ± 0.52
0.0TyrCys: 0.0 ± 0.0
0.713TyrAsp: 0.713 ± 0.358
2.851TyrGlu: 2.851 ± 1.433
4.277TyrPhe: 4.277 ± 0.913
1.426TyrGly: 1.426 ± 1.756
2.138TyrHis: 2.138 ± 1.398
2.851TyrIle: 2.851 ± 1.433
3.564TyrLys: 3.564 ± 0.555
6.415TyrLeu: 6.415 ± 3.223
0.713TyrMet: 0.713 ± 0.358
3.564TyrAsn: 3.564 ± 1.791
3.564TyrPro: 3.564 ± 0.681
2.138TyrGln: 2.138 ± 0.162
1.426TyrArg: 1.426 ± 0.52
2.138TyrSer: 2.138 ± 0.162
0.713TyrThr: 0.713 ± 0.358
2.138TyrVal: 2.138 ± 1.074
0.0TyrTrp: 0.0 ± 0.0
0.713TyrTyr: 0.713 ± 0.358
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1404 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski