Amino acid dipepetide frequency for Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.921AlaAla: 11.921 ± 0.112	1.199AlaCys: 1.199 ± 0.028	5.862AlaAsp: 5.862 ± 0.055	6.271AlaGlu: 6.271 ± 0.076	3.7AlaPhe: 3.7 ± 0.052	8.482AlaGly: 8.482 ± 0.098	2.215AlaHis: 2.215 ± 0.041	5.302AlaIle: 5.302 ± 0.066	3.649AlaLys: 3.649 ± 0.061	13.019AlaLeu: 13.019 ± 0.125	2.772AlaMet: 2.772 ± 0.046	3.121AlaAsn: 3.121 ± 0.056	4.54AlaPro: 4.54 ± 0.065	5.21AlaGln: 5.21 ± 0.066	6.726AlaArg: 6.726 ± 0.058	6.461AlaSer: 6.461 ± 0.067	4.957AlaThr: 4.957 ± 0.066	7.234AlaVal: 7.234 ± 0.058	1.453AlaTrp: 1.453 ± 0.033	2.561AlaTyr: 2.561 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	1.062CysAla: 1.062 ± 0.023	0.133CysCys: 0.133 ± 0.009	0.548CysAsp: 0.548 ± 0.019	0.533CysGlu: 0.533 ± 0.018	0.346CysPhe: 0.346 ± 0.013	0.889CysGly: 0.889 ± 0.019	0.246CysHis: 0.246 ± 0.011	0.464CysIle: 0.464 ± 0.016	0.315CysLys: 0.315 ± 0.013	1.09CysLeu: 1.09 ± 0.025	0.23CysMet: 0.23 ± 0.012	0.277CysAsn: 0.277 ± 0.011	0.47CysPro: 0.47 ± 0.017	0.38CysGln: 0.38 ± 0.015	0.597CysArg: 0.597 ± 0.019	0.654CysSer: 0.654 ± 0.018	0.464CysThr: 0.464 ± 0.017	0.702CysVal: 0.702 ± 0.02	0.147CysTrp: 0.147 ± 0.009	0.26CysTyr: 0.26 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	5.749AspAla: 5.749 ± 0.062	0.534AspCys: 0.534 ± 0.017	2.983AspAsp: 2.983 ± 0.049	3.524AspGlu: 3.524 ± 0.046	2.138AspPhe: 2.138 ± 0.033	4.33AspGly: 4.33 ± 0.054	1.172AspHis: 1.172 ± 0.029	2.843AspIle: 2.843 ± 0.041	2.088AspLys: 2.088 ± 0.043	5.919AspLeu: 5.919 ± 0.062	1.26AspMet: 1.26 ± 0.028	1.727AspAsn: 1.727 ± 0.041	2.815AspPro: 2.815 ± 0.042	2.304AspGln: 2.304 ± 0.039	3.175AspArg: 3.175 ± 0.046	3.147AspSer: 3.147 ± 0.037	2.601AspThr: 2.601 ± 0.038	3.793AspVal: 3.793 ± 0.047	0.94AspTrp: 0.94 ± 0.025	1.758AspTyr: 1.758 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	5.761GluAla: 5.761 ± 0.058	0.42GluCys: 0.42 ± 0.017	2.538GluAsp: 2.538 ± 0.04	2.953GluGlu: 2.953 ± 0.053	1.851GluPhe: 1.851 ± 0.031	3.76GluGly: 3.76 ± 0.058	1.684GluHis: 1.684 ± 0.031	2.799GluIle: 2.799 ± 0.048	2.369GluLys: 2.369 ± 0.041	6.597GluLeu: 6.597 ± 0.074	1.331GluMet: 1.331 ± 0.03	1.779GluAsn: 1.779 ± 0.037	2.486GluPro: 2.486 ± 0.046	3.609GluGln: 3.609 ± 0.05	4.508GluArg: 4.508 ± 0.067	2.961GluSer: 2.961 ± 0.045	2.722GluThr: 2.722 ± 0.041	4.014GluVal: 4.014 ± 0.05	0.732GluTrp: 0.732 ± 0.021	1.25GluTyr: 1.25 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.885PheAla: 3.885 ± 0.049	0.471PheCys: 0.471 ± 0.015	2.502PheAsp: 2.502 ± 0.04	2.103PheGlu: 2.103 ± 0.034	1.478PhePhe: 1.478 ± 0.032	3.058PheGly: 3.058 ± 0.044	0.728PheHis: 0.728 ± 0.021	1.918PheIle: 1.918 ± 0.031	1.432PheLys: 1.432 ± 0.029	3.157PheLeu: 3.157 ± 0.047	0.875PheMet: 0.875 ± 0.022	1.444PheAsn: 1.444 ± 0.03	1.374PhePro: 1.374 ± 0.026	1.278PheGln: 1.278 ± 0.026	1.805PheArg: 1.805 ± 0.032	2.706PheSer: 2.706 ± 0.042	1.999PheThr: 1.999 ± 0.037	2.505PheVal: 2.505 ± 0.042	0.525PheTrp: 0.525 ± 0.016	1.044PheTyr: 1.044 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	6.934GlyAla: 6.934 ± 0.083	0.907GlyCys: 0.907 ± 0.021	3.902GlyAsp: 3.902 ± 0.051	4.397GlyGlu: 4.397 ± 0.052	3.287GlyPhe: 3.287 ± 0.049	5.72GlyGly: 5.72 ± 0.082	1.806GlyHis: 1.806 ± 0.032	4.131GlyIle: 4.131 ± 0.051	3.591GlyLys: 3.591 ± 0.055	8.785GlyLeu: 8.785 ± 0.083	2.184GlyMet: 2.184 ± 0.04	2.507GlyAsn: 2.507 ± 0.048	2.522GlyPro: 2.522 ± 0.04	3.526GlyGln: 3.526 ± 0.057	4.651GlyArg: 4.651 ± 0.051	4.773GlySer: 4.773 ± 0.066	3.886GlyThr: 3.886 ± 0.063	5.832GlyVal: 5.832 ± 0.062	1.285GlyTrp: 1.285 ± 0.028	2.42GlyTyr: 2.42 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.27HisAla: 2.27 ± 0.038	0.326HisCys: 0.326 ± 0.014	1.29HisAsp: 1.29 ± 0.029	1.258HisGlu: 1.258 ± 0.027	0.984HisPhe: 0.984 ± 0.025	1.813HisGly: 1.813 ± 0.035	0.616HisHis: 0.616 ± 0.02	1.064HisIle: 1.064 ± 0.026	0.651HisLys: 0.651 ± 0.02	2.55HisLeu: 2.55 ± 0.041	0.545HisMet: 0.545 ± 0.018	0.647HisAsn: 0.647 ± 0.019	1.357HisPro: 1.357 ± 0.029	0.963HisGln: 0.963 ± 0.025	1.382HisArg: 1.382 ± 0.029	1.373HisSer: 1.373 ± 0.028	1.061HisThr: 1.061 ± 0.022	1.437HisVal: 1.437 ± 0.028	0.433HisTrp: 0.433 ± 0.018	0.764HisTyr: 0.764 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.941IleAla: 5.941 ± 0.063	0.54IleCys: 0.54 ± 0.018	3.487IleAsp: 3.487 ± 0.043	3.52IleGlu: 3.52 ± 0.051	1.546IlePhe: 1.546 ± 0.032	4.526IleGly: 4.526 ± 0.058	1.024IleHis: 1.024 ± 0.027	2.215IleIle: 2.215 ± 0.042	1.948IleLys: 1.948 ± 0.037	4.166IleLeu: 4.166 ± 0.061	0.906IleMet: 0.906 ± 0.023	1.976IleAsn: 1.976 ± 0.038	2.23IlePro: 2.23 ± 0.037	1.719IleGln: 1.719 ± 0.032	2.933IleArg: 2.933 ± 0.038	3.272IleSer: 3.272 ± 0.044	2.778IleThr: 2.778 ± 0.04	3.376IleVal: 3.376 ± 0.055	0.555IleTrp: 0.555 ± 0.02	1.183IleTyr: 1.183 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.361LysAla: 4.361 ± 0.062	0.201LysCys: 0.201 ± 0.01	1.875LysAsp: 1.875 ± 0.037	1.772LysGlu: 1.772 ± 0.039	0.924LysPhe: 0.924 ± 0.024	2.833LysGly: 2.833 ± 0.05	0.834LysHis: 0.834 ± 0.023	1.78LysIle: 1.78 ± 0.039	1.575LysLys: 1.575 ± 0.046	3.943LysLeu: 3.943 ± 0.06	0.834LysMet: 0.834 ± 0.026	1.176LysAsn: 1.176 ± 0.027	2.257LysPro: 2.257 ± 0.043	1.616LysGln: 1.616 ± 0.032	2.491LysArg: 2.491 ± 0.044	2.153LysSer: 2.153 ± 0.042	2.192LysThr: 2.192 ± 0.039	2.952LysVal: 2.952 ± 0.05	0.376LysTrp: 0.376 ± 0.015	0.733LysTyr: 0.733 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.942LeuAla: 12.942 ± 0.106	1.169LeuCys: 1.169 ± 0.028	6.578LeuAsp: 6.578 ± 0.071	6.153LeuGlu: 6.153 ± 0.065	3.917LeuPhe: 3.917 ± 0.057	8.65LeuGly: 8.65 ± 0.083	2.433LeuHis: 2.433 ± 0.043	5.863LeuIle: 5.863 ± 0.06	4.597LeuLys: 4.597 ± 0.059	12.55LeuLeu: 12.55 ± 0.137	2.642LeuMet: 2.642 ± 0.042	3.958LeuAsn: 3.958 ± 0.061	6.039LeuPro: 6.039 ± 0.078	4.561LeuGln: 4.561 ± 0.061	7.03LeuArg: 7.03 ± 0.084	7.612LeuSer: 7.612 ± 0.072	6.063LeuThr: 6.063 ± 0.074	7.297LeuVal: 7.297 ± 0.076	1.308LeuTrp: 1.308 ± 0.027	2.505LeuTyr: 2.505 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.631MetAla: 2.631 ± 0.046	0.186MetCys: 0.186 ± 0.009	1.105MetAsp: 1.105 ± 0.024	0.959MetGlu: 0.959 ± 0.024	0.747MetPhe: 0.747 ± 0.023	1.722MetGly: 1.722 ± 0.034	0.511MetHis: 0.511 ± 0.016	1.265MetIle: 1.265 ± 0.028	0.964MetLys: 0.964 ± 0.023	2.757MetLeu: 2.757 ± 0.042	0.537MetMet: 0.537 ± 0.023	0.937MetAsn: 0.937 ± 0.023	1.383MetPro: 1.383 ± 0.027	1.1MetGln: 1.1 ± 0.023	1.57MetArg: 1.57 ± 0.03	1.846MetSer: 1.846 ± 0.033	1.567MetThr: 1.567 ± 0.028	1.561MetVal: 1.561 ± 0.032	0.191MetTrp: 0.191 ± 0.01	0.405MetTyr: 0.405 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.424AsnAla: 3.424 ± 0.056	0.304AsnCys: 0.304 ± 0.013	1.825AsnAsp: 1.825 ± 0.034	1.609AsnGlu: 1.609 ± 0.032	1.1AsnPhe: 1.1 ± 0.029	2.751AsnGly: 2.751 ± 0.052	0.686AsnHis: 0.686 ± 0.021	1.543AsnIle: 1.543 ± 0.032	1.047AsnLys: 1.047 ± 0.027	3.549AsnLeu: 3.549 ± 0.045	0.69AsnMet: 0.69 ± 0.021	1.077AsnAsn: 1.077 ± 0.039	2.011AsnPro: 2.011 ± 0.035	1.328AsnGln: 1.328 ± 0.04	1.986AsnArg: 1.986 ± 0.03	1.877AsnSer: 1.877 ± 0.045	1.761AsnThr: 1.761 ± 0.043	2.192AsnVal: 2.192 ± 0.037	0.502AsnTrp: 0.502 ± 0.018	0.858AsnTyr: 0.858 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.406ProAla: 5.406 ± 0.07	0.349ProCys: 0.349 ± 0.014	3.082ProAsp: 3.082 ± 0.046	3.258ProGlu: 3.258 ± 0.047	1.85ProPhe: 1.85 ± 0.032	3.818ProGly: 3.818 ± 0.053	1.071ProHis: 1.071 ± 0.029	2.099ProIle: 2.099 ± 0.037	1.658ProLys: 1.658 ± 0.036	5.372ProLeu: 5.372 ± 0.07	1.17ProMet: 1.17 ± 0.028	1.343ProAsn: 1.343 ± 0.028	1.953ProPro: 1.953 ± 0.047	2.173ProGln: 2.173 ± 0.043	2.414ProArg: 2.414 ± 0.043	2.567ProSer: 2.567 ± 0.046	2.352ProThr: 2.352 ± 0.043	3.998ProVal: 3.998 ± 0.054	0.709ProTrp: 0.709 ± 0.024	1.176ProTyr: 1.176 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	5.689GlnAla: 5.689 ± 0.077	0.33GlnCys: 0.33 ± 0.013	1.883GlnAsp: 1.883 ± 0.031	1.979GlnGlu: 1.979 ± 0.032	1.349GlnPhe: 1.349 ± 0.029	3.284GlnGly: 3.284 ± 0.049	1.146GlnHis: 1.146 ± 0.024	2.184GlnIle: 2.184 ± 0.037	1.454GlnLys: 1.454 ± 0.032	5.315GlnLeu: 5.315 ± 0.073	1.104GlnMet: 1.104 ± 0.025	1.281GlnAsn: 1.281 ± 0.028	2.358GlnPro: 2.358 ± 0.044	2.689GlnGln: 2.689 ± 0.065	3.535GlnArg: 3.535 ± 0.064	2.519GlnSer: 2.519 ± 0.047	2.233GlnThr: 2.233 ± 0.04	3.455GlnVal: 3.455 ± 0.051	0.711GlnTrp: 0.711 ± 0.021	1.026GlnTyr: 1.026 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	5.631ArgAla: 5.631 ± 0.063	0.565ArgCys: 0.565 ± 0.017	3.44ArgAsp: 3.44 ± 0.051	3.97ArgGlu: 3.97 ± 0.055	2.694ArgPhe: 2.694 ± 0.04	3.781ArgGly: 3.781 ± 0.045	1.675ArgHis: 1.675 ± 0.034	3.481ArgIle: 3.481 ± 0.046	2.233ArgLys: 2.233 ± 0.036	7.989ArgLeu: 7.989 ± 0.092	1.673ArgMet: 1.673 ± 0.03	2.072ArgAsn: 2.072 ± 0.041	2.718ArgPro: 2.718 ± 0.044	3.299ArgGln: 3.299 ± 0.051	3.984ArgArg: 3.984 ± 0.058	3.69ArgSer: 3.69 ± 0.049	2.873ArgThr: 2.873 ± 0.041	4.256ArgVal: 4.256 ± 0.058	1.003ArgTrp: 1.003 ± 0.024	1.984ArgTyr: 1.984 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.548SerAla: 6.548 ± 0.075	0.522SerCys: 0.522 ± 0.017	3.168SerAsp: 3.168 ± 0.048	3.234SerGlu: 3.234 ± 0.047	2.321SerPhe: 2.321 ± 0.034	5.527SerGly: 5.527 ± 0.059	1.418SerHis: 1.418 ± 0.028	3.07SerIle: 3.07 ± 0.043	2.045SerLys: 2.045 ± 0.042	7.123SerLeu: 7.123 ± 0.085	1.547SerMet: 1.547 ± 0.03	1.941SerAsn: 1.941 ± 0.035	2.844SerPro: 2.844 ± 0.037	2.585SerGln: 2.585 ± 0.041	3.848SerArg: 3.848 ± 0.051	4.025SerSer: 4.025 ± 0.058	3.303SerThr: 3.303 ± 0.055	4.471SerVal: 4.471 ± 0.05	0.835SerTrp: 0.835 ± 0.021	1.575SerTyr: 1.575 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.351ThrAla: 5.351 ± 0.072	0.481ThrCys: 0.481 ± 0.015	2.738ThrAsp: 2.738 ± 0.044	2.561ThrGlu: 2.561 ± 0.04	1.913ThrPhe: 1.913 ± 0.037	4.291ThrGly: 4.291 ± 0.062	1.18ThrHis: 1.18 ± 0.022	2.118ThrIle: 2.118 ± 0.041	1.334ThrLys: 1.334 ± 0.032	6.951ThrLeu: 6.951 ± 0.078	0.883ThrMet: 0.883 ± 0.023	1.301ThrAsn: 1.301 ± 0.034	3.26ThrPro: 3.26 ± 0.048	2.216ThrGln: 2.216 ± 0.034	3.23ThrArg: 3.23 ± 0.04	3.059ThrSer: 3.059 ± 0.054	2.67ThrThr: 2.67 ± 0.044	3.739ThrVal: 3.739 ± 0.051	0.681ThrTrp: 0.681 ± 0.02	1.308ThrTyr: 1.308 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	7.483ValAla: 7.483 ± 0.066	0.733ValCys: 0.733 ± 0.021	3.976ValAsp: 3.976 ± 0.049	4.239ValGlu: 4.239 ± 0.049	2.638ValPhe: 2.638 ± 0.044	4.963ValGly: 4.963 ± 0.063	1.401ValHis: 1.401 ± 0.029	3.983ValIle: 3.983 ± 0.047	2.548ValLys: 2.548 ± 0.042	7.926ValLeu: 7.926 ± 0.082	1.854ValMet: 1.854 ± 0.033	2.313ValAsn: 2.313 ± 0.039	3.261ValPro: 3.261 ± 0.053	2.863ValGln: 2.863 ± 0.04	4.188ValArg: 4.188 ± 0.046	4.754ValSer: 4.754 ± 0.061	3.863ValThr: 3.863 ± 0.051	5.394ValVal: 5.394 ± 0.059	0.902ValTrp: 0.902 ± 0.023	1.604ValTyr: 1.604 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.165TrpAla: 1.165 ± 0.034	0.156TrpCys: 0.156 ± 0.009	0.613TrpAsp: 0.613 ± 0.02	0.578TrpGlu: 0.578 ± 0.015	0.502TrpPhe: 0.502 ± 0.017	0.871TrpGly: 0.871 ± 0.022	0.375TrpHis: 0.375 ± 0.014	0.686TrpIle: 0.686 ± 0.023	0.524TrpLys: 0.524 ± 0.019	2.107TrpLeu: 2.107 ± 0.038	0.386TrpMet: 0.386 ± 0.014	0.453TrpAsn: 0.453 ± 0.014	0.645TrpPro: 0.645 ± 0.02	0.855TrpGln: 0.855 ± 0.025	1.01TrpArg: 1.01 ± 0.027	0.857TrpSer: 0.857 ± 0.026	0.65TrpThr: 0.65 ± 0.02	0.951TrpVal: 0.951 ± 0.021	0.237TrpTrp: 0.237 ± 0.013	0.329TrpTyr: 0.329 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.501TyrAla: 2.501 ± 0.037	0.279TyrCys: 0.279 ± 0.012	1.403TyrAsp: 1.403 ± 0.033	1.25TyrGlu: 1.25 ± 0.028	1.002TyrPhe: 1.002 ± 0.023	1.978TyrGly: 1.978 ± 0.031	0.567TyrHis: 0.567 ± 0.019	1.036TyrIle: 1.036 ± 0.027	0.856TyrLys: 0.856 ± 0.024	3.003TyrLeu: 3.003 ± 0.038	0.521TyrMet: 0.521 ± 0.018	0.789TyrAsn: 0.789 ± 0.023	1.292TyrPro: 1.292 ± 0.03	1.253TyrGln: 1.253 ± 0.024	1.947TyrArg: 1.947 ± 0.036	1.644TyrSer: 1.644 ± 0.03	1.268TyrThr: 1.268 ± 0.027	1.727TyrVal: 1.727 ± 0.032	0.426TyrTrp: 0.426 ± 0.015	0.698TyrTyr: 0.698 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5431 proteins (1794801 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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