Amino acid dipepetide frequency for Aquimarina amphilecti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.492AlaAla: 3.492 ± 0.067	0.472AlaCys: 0.472 ± 0.02	2.93AlaAsp: 2.93 ± 0.051	3.363AlaGlu: 3.363 ± 0.065	2.893AlaPhe: 2.893 ± 0.046	3.767AlaGly: 3.767 ± 0.064	0.894AlaHis: 0.894 ± 0.026	5.162AlaIle: 5.162 ± 0.067	4.194AlaLys: 4.194 ± 0.068	5.26AlaLeu: 5.26 ± 0.075	1.243AlaMet: 1.243 ± 0.029	3.182AlaAsn: 3.182 ± 0.046	1.713AlaPro: 1.713 ± 0.037	2.023AlaGln: 2.023 ± 0.041	1.773AlaArg: 1.773 ± 0.04	4.026AlaSer: 4.026 ± 0.05	3.425AlaThr: 3.425 ± 0.061	3.448AlaVal: 3.448 ± 0.056	0.537AlaTrp: 0.537 ± 0.02	2.229AlaTyr: 2.229 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.395CysAla: 0.395 ± 0.015	0.109CysCys: 0.109 ± 0.009	0.448CysAsp: 0.448 ± 0.02	0.446CysGlu: 0.446 ± 0.017	0.406CysPhe: 0.406 ± 0.018	0.592CysGly: 0.592 ± 0.02	0.156CysHis: 0.156 ± 0.012	0.633CysIle: 0.633 ± 0.02	0.493CysLys: 0.493 ± 0.018	0.625CysLeu: 0.625 ± 0.02	0.142CysMet: 0.142 ± 0.01	0.485CysAsn: 0.485 ± 0.019	0.307CysPro: 0.307 ± 0.018	0.195CysGln: 0.195 ± 0.012	0.202CysArg: 0.202 ± 0.012	0.612CysSer: 0.612 ± 0.022	0.456CysThr: 0.456 ± 0.019	0.422CysVal: 0.422 ± 0.019	0.076CysTrp: 0.076 ± 0.006	0.314CysTyr: 0.314 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.326AspAla: 3.326 ± 0.055	0.452AspCys: 0.452 ± 0.021	3.253AspAsp: 3.253 ± 0.057	3.523AspGlu: 3.523 ± 0.056	3.681AspPhe: 3.681 ± 0.063	3.961AspGly: 3.961 ± 0.084	0.988AspHis: 0.988 ± 0.023	4.971AspIle: 4.971 ± 0.075	4.17AspLys: 4.17 ± 0.052	5.202AspLeu: 5.202 ± 0.061	1.001AspMet: 1.001 ± 0.026	3.654AspAsn: 3.654 ± 0.057	1.997AspPro: 1.997 ± 0.04	2.092AspGln: 2.092 ± 0.04	1.91AspArg: 1.91 ± 0.034	3.486AspSer: 3.486 ± 0.055	3.189AspThr: 3.189 ± 0.05	3.579AspVal: 3.579 ± 0.059	0.812AspTrp: 0.812 ± 0.021	2.743AspTyr: 2.743 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	3.758GluAla: 3.758 ± 0.07	0.345GluCys: 0.345 ± 0.015	3.737GluAsp: 3.737 ± 0.05	5.253GluGlu: 5.253 ± 0.081	2.917GluPhe: 2.917 ± 0.044	3.729GluGly: 3.729 ± 0.053	1.042GluHis: 1.042 ± 0.027	5.916GluIle: 5.916 ± 0.072	5.859GluLys: 5.859 ± 0.083	6.18GluLeu: 6.18 ± 0.071	1.378GluMet: 1.378 ± 0.033	4.671GluAsn: 4.671 ± 0.057	1.501GluPro: 1.501 ± 0.029	2.179GluGln: 2.179 ± 0.04	2.314GluArg: 2.314 ± 0.048	3.58GluSer: 3.58 ± 0.049	3.635GluThr: 3.635 ± 0.051	4.274GluVal: 4.274 ± 0.057	0.559GluTrp: 0.559 ± 0.022	2.696GluTyr: 2.696 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	2.685PheAla: 2.685 ± 0.047	0.447PheCys: 0.447 ± 0.019	3.477PheAsp: 3.477 ± 0.054	3.251PheGlu: 3.251 ± 0.046	2.872PhePhe: 2.872 ± 0.05	3.612PheGly: 3.612 ± 0.053	0.783PheHis: 0.783 ± 0.026	4.206PheIle: 4.206 ± 0.052	3.619PheLys: 3.619 ± 0.052	4.877PheLeu: 4.877 ± 0.07	1.07PheMet: 1.07 ± 0.028	3.286PheAsn: 3.286 ± 0.049	1.636PhePro: 1.636 ± 0.036	1.468PheGln: 1.468 ± 0.031	1.788PheArg: 1.788 ± 0.031	4.245PheSer: 4.245 ± 0.059	3.189PheThr: 3.189 ± 0.051	2.929PheVal: 2.929 ± 0.05	0.616PheTrp: 0.616 ± 0.02	2.325PheTyr: 2.325 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	3.874GlyAla: 3.874 ± 0.054	0.588GlyCys: 0.588 ± 0.027	3.703GlyAsp: 3.703 ± 0.067	3.525GlyGlu: 3.525 ± 0.057	3.721GlyPhe: 3.721 ± 0.053	4.591GlyGly: 4.591 ± 0.075	1.016GlyHis: 1.016 ± 0.027	5.627GlyIle: 5.627 ± 0.065	4.626GlyLys: 4.626 ± 0.061	5.523GlyLeu: 5.523 ± 0.062	1.443GlyMet: 1.443 ± 0.031	4.131GlyAsn: 4.131 ± 0.069	1.334GlyPro: 1.334 ± 0.036	1.801GlyGln: 1.801 ± 0.038	2.029GlyArg: 2.029 ± 0.033	4.274GlySer: 4.274 ± 0.061	4.254GlyThr: 4.254 ± 0.089	4.361GlyVal: 4.361 ± 0.055	0.771GlyTrp: 0.771 ± 0.023	2.872GlyTyr: 2.872 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	0.766HisAla: 0.766 ± 0.026	0.162HisCys: 0.162 ± 0.01	0.757HisAsp: 0.757 ± 0.024	0.852HisGlu: 0.852 ± 0.028	1.062HisPhe: 1.062 ± 0.03	0.948HisGly: 0.948 ± 0.028	0.447HisHis: 0.447 ± 0.018	1.454HisIle: 1.454 ± 0.036	1.255HisLys: 1.255 ± 0.026	1.621HisLeu: 1.621 ± 0.036	0.33HisMet: 0.33 ± 0.015	1.04HisAsn: 1.04 ± 0.03	0.757HisPro: 0.757 ± 0.024	0.7HisGln: 0.7 ± 0.024	0.624HisArg: 0.624 ± 0.021	1.026HisSer: 1.026 ± 0.024	0.972HisThr: 0.972 ± 0.024	0.788HisVal: 0.788 ± 0.026	0.196HisTrp: 0.196 ± 0.011	0.766HisTyr: 0.766 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.381IleAla: 5.381 ± 0.073	0.664IleCys: 0.664 ± 0.021	5.483IleAsp: 5.483 ± 0.066	5.809IleGlu: 5.809 ± 0.066	3.782IlePhe: 3.782 ± 0.064	5.408IleGly: 5.408 ± 0.056	1.467IleHis: 1.467 ± 0.036	6.929IleIle: 6.929 ± 0.083	6.391IleLys: 6.391 ± 0.086	7.451IleLeu: 7.451 ± 0.089	1.367IleMet: 1.367 ± 0.032	5.365IleAsn: 5.365 ± 0.069	3.412IlePro: 3.412 ± 0.051	2.683IleGln: 2.683 ± 0.043	2.665IleArg: 2.665 ± 0.044	6.591IleSer: 6.591 ± 0.078	5.567IleThr: 5.567 ± 0.066	5.005IleVal: 5.005 ± 0.063	0.777IleTrp: 0.777 ± 0.024	3.026IleTyr: 3.026 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.3LysAla: 4.3 ± 0.064	0.321LysCys: 0.321 ± 0.015	4.521LysAsp: 4.521 ± 0.07	6.798LysGlu: 6.798 ± 0.085	2.862LysPhe: 2.862 ± 0.038	4.478LysGly: 4.478 ± 0.064	1.317LysHis: 1.317 ± 0.035	6.517LysIle: 6.517 ± 0.072	7.645LysLys: 7.645 ± 0.094	6.437LysLeu: 6.437 ± 0.069	1.81LysMet: 1.81 ± 0.039	5.539LysAsn: 5.539 ± 0.076	2.23LysPro: 2.23 ± 0.042	2.626LysGln: 2.626 ± 0.045	2.93LysArg: 2.93 ± 0.041	4.766LysSer: 4.766 ± 0.069	4.668LysThr: 4.668 ± 0.06	4.628LysVal: 4.628 ± 0.058	0.784LysTrp: 0.784 ± 0.025	3.067LysTyr: 3.067 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	4.874LeuAla: 4.874 ± 0.067	0.689LeuCys: 0.689 ± 0.023	5.16LeuAsp: 5.16 ± 0.056	6.055LeuGlu: 6.055 ± 0.079	4.911LeuPhe: 4.911 ± 0.065	5.676LeuGly: 5.676 ± 0.061	1.456LeuHis: 1.456 ± 0.033	7.498LeuIle: 7.498 ± 0.091	7.492LeuLys: 7.492 ± 0.08	8.833LeuLeu: 8.833 ± 0.11	1.915LeuMet: 1.915 ± 0.042	5.449LeuAsn: 5.449 ± 0.071	3.21LeuPro: 3.21 ± 0.046	3.094LeuGln: 3.094 ± 0.054	3.11LeuArg: 3.11 ± 0.046	6.939LeuSer: 6.939 ± 0.075	5.024LeuThr: 5.024 ± 0.068	5.163LeuVal: 5.163 ± 0.057	0.872LeuTrp: 0.872 ± 0.026	3.335LeuTyr: 3.335 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.224MetAla: 1.224 ± 0.029	0.132MetCys: 0.132 ± 0.009	1.096MetAsp: 1.096 ± 0.027	1.225MetGlu: 1.225 ± 0.026	0.812MetPhe: 0.812 ± 0.032	1.225MetGly: 1.225 ± 0.03	0.345MetHis: 0.345 ± 0.017	1.726MetIle: 1.726 ± 0.039	2.133MetLys: 2.133 ± 0.037	1.727MetLeu: 1.727 ± 0.035	0.522MetMet: 0.522 ± 0.02	1.366MetAsn: 1.366 ± 0.028	0.719MetPro: 0.719 ± 0.023	0.682MetGln: 0.682 ± 0.021	0.781MetArg: 0.781 ± 0.023	1.347MetSer: 1.347 ± 0.028	1.05MetThr: 1.05 ± 0.027	1.159MetVal: 1.159 ± 0.032	0.163MetTrp: 0.163 ± 0.011	0.687MetTyr: 0.687 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.549AsnAla: 3.549 ± 0.046	0.517AsnCys: 0.517 ± 0.023	3.734AsnAsp: 3.734 ± 0.064	3.828AsnGlu: 3.828 ± 0.05	3.225AsnPhe: 3.225 ± 0.049	4.478AsnGly: 4.478 ± 0.071	1.072AsnHis: 1.072 ± 0.026	5.23AsnIle: 5.23 ± 0.07	4.657AsnLys: 4.657 ± 0.063	5.456AsnLeu: 5.456 ± 0.074	1.212AsnMet: 1.212 ± 0.03	4.526AsnAsn: 4.526 ± 0.073	2.77AsnPro: 2.77 ± 0.052	2.413AsnGln: 2.413 ± 0.044	2.311AsnArg: 2.311 ± 0.042	4.314AsnSer: 4.314 ± 0.055	4.216AsnThr: 4.216 ± 0.055	3.614AsnVal: 3.614 ± 0.054	0.846AsnTrp: 0.846 ± 0.026	2.888AsnTyr: 2.888 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	1.658ProAla: 1.658 ± 0.037	0.212ProCys: 0.212 ± 0.012	2.091ProAsp: 2.091 ± 0.038	2.619ProGlu: 2.619 ± 0.037	1.828ProPhe: 1.828 ± 0.033	1.91ProGly: 1.91 ± 0.042	0.532ProHis: 0.532 ± 0.021	2.825ProIle: 2.825 ± 0.047	2.47ProLys: 2.47 ± 0.046	2.744ProLeu: 2.744 ± 0.04	0.622ProMet: 0.622 ± 0.021	2.313ProAsn: 2.313 ± 0.042	0.837ProPro: 0.837 ± 0.029	1.006ProGln: 1.006 ± 0.023	0.906ProArg: 0.906 ± 0.024	2.308ProSer: 2.308 ± 0.036	1.91ProThr: 1.91 ± 0.043	2.147ProVal: 2.147 ± 0.042	0.344ProTrp: 0.344 ± 0.015	1.321ProTyr: 1.321 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	1.715GlnAla: 1.715 ± 0.036	0.18GlnCys: 0.18 ± 0.012	1.77GlnAsp: 1.77 ± 0.034	2.445GlnGlu: 2.445 ± 0.044	1.648GlnPhe: 1.648 ± 0.033	1.857GlnGly: 1.857 ± 0.037	0.513GlnHis: 0.513 ± 0.019	2.634GlnIle: 2.634 ± 0.033	2.932GlnLys: 2.932 ± 0.047	3.301GlnLeu: 3.301 ± 0.044	0.716GlnMet: 0.716 ± 0.022	2.25GlnAsn: 2.25 ± 0.039	0.987GlnPro: 0.987 ± 0.026	1.305GlnGln: 1.305 ± 0.034	1.165GlnArg: 1.165 ± 0.032	2.023GlnSer: 2.023 ± 0.04	1.833GlnThr: 1.833 ± 0.033	1.9GlnVal: 1.9 ± 0.033	0.416GlnTrp: 0.416 ± 0.018	1.379GlnTyr: 1.379 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	1.823ArgAla: 1.823 ± 0.036	0.211ArgCys: 0.211 ± 0.01	1.782ArgAsp: 1.782 ± 0.034	2.097ArgGlu: 2.097 ± 0.042	1.936ArgPhe: 1.936 ± 0.037	1.885ArgGly: 1.885 ± 0.043	0.532ArgHis: 0.532 ± 0.021	3.075ArgIle: 3.075 ± 0.048	2.85ArgLys: 2.85 ± 0.049	3.206ArgLeu: 3.206 ± 0.052	0.826ArgMet: 0.826 ± 0.02	2.233ArgAsn: 2.233 ± 0.044	0.976ArgPro: 0.976 ± 0.025	1.052ArgGln: 1.052 ± 0.029	1.294ArgArg: 1.294 ± 0.032	2.146ArgSer: 2.146 ± 0.039	1.866ArgThr: 1.866 ± 0.039	2.049ArgVal: 2.049 ± 0.035	0.406ArgTrp: 0.406 ± 0.015	1.561ArgTyr: 1.561 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	3.366SerAla: 3.366 ± 0.053	0.738SerCys: 0.738 ± 0.023	3.941SerAsp: 3.941 ± 0.053	4.363SerGlu: 4.363 ± 0.058	4.203SerPhe: 4.203 ± 0.06	4.914SerGly: 4.914 ± 0.079	1.03SerHis: 1.03 ± 0.028	6.054SerIle: 6.054 ± 0.071	5.237SerLys: 5.237 ± 0.07	6.447SerLeu: 6.447 ± 0.072	1.3SerMet: 1.3 ± 0.032	4.412SerAsn: 4.412 ± 0.066	2.053SerPro: 2.053 ± 0.042	2.12SerGln: 2.12 ± 0.036	2.225SerArg: 2.225 ± 0.04	4.928SerSer: 4.928 ± 0.074	3.753SerThr: 3.753 ± 0.051	3.92SerVal: 3.92 ± 0.057	0.825SerTrp: 0.825 ± 0.027	3.221SerTyr: 3.221 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.425ThrAla: 3.425 ± 0.06	0.352ThrCys: 0.352 ± 0.019	3.376ThrAsp: 3.376 ± 0.06	3.545ThrGlu: 3.545 ± 0.049	3.05ThrPhe: 3.05 ± 0.048	4.097ThrGly: 4.097 ± 0.075	0.951ThrHis: 0.951 ± 0.024	5.669ThrIle: 5.669 ± 0.072	4.161ThrLys: 4.161 ± 0.061	5.275ThrLeu: 5.275 ± 0.063	0.974ThrMet: 0.974 ± 0.027	3.802ThrAsn: 3.802 ± 0.062	2.536ThrPro: 2.536 ± 0.047	1.754ThrGln: 1.754 ± 0.03	1.684ThrArg: 1.684 ± 0.035	4.297ThrSer: 4.297 ± 0.056	3.791ThrThr: 3.791 ± 0.068	3.778ThrVal: 3.778 ± 0.061	0.607ThrTrp: 0.607 ± 0.025	2.585ThrTyr: 2.585 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	3.557ValAla: 3.557 ± 0.055	0.47ValCys: 0.47 ± 0.016	3.551ValAsp: 3.551 ± 0.058	3.441ValGlu: 3.441 ± 0.051	3.494ValPhe: 3.494 ± 0.055	3.665ValGly: 3.665 ± 0.058	0.956ValHis: 0.956 ± 0.027	5.125ValIle: 5.125 ± 0.067	4.025ValLys: 4.025 ± 0.051	5.764ValLeu: 5.764 ± 0.074	1.255ValMet: 1.255 ± 0.026	3.596ValAsn: 3.596 ± 0.051	1.976ValPro: 1.976 ± 0.035	1.753ValGln: 1.753 ± 0.034	1.964ValArg: 1.964 ± 0.035	4.698ValSer: 4.698 ± 0.064	3.779ValThr: 3.779 ± 0.075	3.949ValVal: 3.949 ± 0.059	0.575ValTrp: 0.575 ± 0.022	2.348ValTyr: 2.348 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	0.537TrpAla: 0.537 ± 0.019	0.112TrpCys: 0.112 ± 0.008	0.671TrpAsp: 0.671 ± 0.021	0.671TrpGlu: 0.671 ± 0.021	0.574TrpPhe: 0.574 ± 0.021	0.656TrpGly: 0.656 ± 0.024	0.2TrpHis: 0.2 ± 0.013	0.871TrpIle: 0.871 ± 0.027	0.857TrpLys: 0.857 ± 0.025	0.95TrpLeu: 0.95 ± 0.027	0.307TrpMet: 0.307 ± 0.014	0.799TrpAsn: 0.799 ± 0.027	0.246TrpPro: 0.246 ± 0.013	0.394TrpGln: 0.394 ± 0.017	0.427TrpArg: 0.427 ± 0.02	0.709TrpSer: 0.709 ± 0.024	0.585TrpThr: 0.585 ± 0.026	0.593TrpVal: 0.593 ± 0.023	0.173TrpTrp: 0.173 ± 0.012	0.513TrpTyr: 0.513 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.319TyrAla: 2.319 ± 0.041	0.341TyrCys: 0.341 ± 0.014	2.51TyrAsp: 2.51 ± 0.046	2.414TyrGlu: 2.414 ± 0.036	2.507TyrPhe: 2.507 ± 0.04	2.617TyrGly: 2.617 ± 0.04	0.823TyrHis: 0.823 ± 0.022	3.1TyrIle: 3.1 ± 0.049	3.179TyrLys: 3.179 ± 0.047	3.874TyrLeu: 3.874 ± 0.056	0.689TyrMet: 0.689 ± 0.022	2.755TyrAsn: 2.755 ± 0.047	1.404TyrPro: 1.404 ± 0.029	1.629TyrGln: 1.629 ± 0.032	1.705TyrArg: 1.705 ± 0.032	2.736TyrSer: 2.736 ± 0.045	2.547TyrThr: 2.547 ± 0.048	2.235TyrVal: 2.235 ± 0.039	0.488TyrTrp: 0.488 ± 0.017	1.98TyrTyr: 1.98 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4646 proteins (1587142 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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