Amino acid dipepetide frequency for Onion yellows phytoplasma (strain OY-M)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.058AlaAla: 2.058 ± 0.115
0.701AlaCys: 0.701 ± 0.061
1.504AlaAsp: 1.504 ± 0.099
1.646AlaGlu: 1.646 ± 0.103
2.812AlaPhe: 2.812 ± 0.135
1.852AlaGly: 1.852 ± 0.118
0.892AlaHis: 0.892 ± 0.069
3.812AlaIle: 3.812 ± 0.161
4.635AlaLys: 4.635 ± 0.195
6.208AlaLeu: 6.208 ± 0.177
0.941AlaMet: 0.941 ± 0.085
2.724AlaAsn: 2.724 ± 0.112
1.308AlaPro: 1.308 ± 0.077
2.724AlaGln: 2.724 ± 0.116
1.352AlaArg: 1.352 ± 0.092
3.043AlaSer: 3.043 ± 0.13
2.665AlaThr: 2.665 ± 0.113
2.244AlaVal: 2.244 ± 0.123
0.211AlaTrp: 0.211 ± 0.032
1.769AlaTyr: 1.769 ± 0.094
0.0AlaXaa: 0.0 ± 0.0
Cys
0.353CysAla: 0.353 ± 0.045
0.348CysCys: 0.348 ± 0.05
0.495CysAsp: 0.495 ± 0.05
0.461CysGlu: 0.461 ± 0.054
0.73CysPhe: 0.73 ± 0.071
0.549CysGly: 0.549 ± 0.06
0.294CysHis: 0.294 ± 0.042
0.583CysIle: 0.583 ± 0.062
0.799CysLys: 0.799 ± 0.064
1.225CysLeu: 1.225 ± 0.08
0.201CysMet: 0.201 ± 0.026
0.686CysAsn: 0.686 ± 0.055
0.456CysPro: 0.456 ± 0.041
0.691CysGln: 0.691 ± 0.055
0.289CysArg: 0.289 ± 0.034
0.5CysSer: 0.5 ± 0.054
0.436CysThr: 0.436 ± 0.043
0.617CysVal: 0.617 ± 0.049
0.122CysTrp: 0.122 ± 0.026
0.529CysTyr: 0.529 ± 0.057
0.0CysXaa: 0.0 ± 0.0
Asp
2.195AspAla: 2.195 ± 0.126
0.358AspCys: 0.358 ± 0.045
2.229AspAsp: 2.229 ± 0.134
2.817AspGlu: 2.817 ± 0.138
3.498AspPhe: 3.498 ± 0.122
1.945AspGly: 1.945 ± 0.106
0.789AspHis: 0.789 ± 0.058
4.165AspIle: 4.165 ± 0.137
5.203AspLys: 5.203 ± 0.171
5.463AspLeu: 5.463 ± 0.175
0.573AspMet: 0.573 ± 0.05
2.876AspAsn: 2.876 ± 0.13
1.583AspPro: 1.583 ± 0.092
1.94AspGln: 1.94 ± 0.114
1.102AspArg: 1.102 ± 0.071
2.313AspSer: 2.313 ± 0.115
2.17AspThr: 2.17 ± 0.106
2.381AspVal: 2.381 ± 0.121
0.269AspTrp: 0.269 ± 0.042
2.097AspTyr: 2.097 ± 0.12
0.0AspXaa: 0.0 ± 0.0
Glu
3.082GluAla: 3.082 ± 0.145
0.416GluCys: 0.416 ± 0.048
2.112GluAsp: 2.112 ± 0.115
4.262GluGlu: 4.262 ± 0.171
2.308GluPhe: 2.308 ± 0.114
2.675GluGly: 2.675 ± 0.124
0.686GluHis: 0.686 ± 0.071
6.56GluIle: 6.56 ± 0.193
7.77GluLys: 7.77 ± 0.213
5.811GluLeu: 5.811 ± 0.204
1.254GluMet: 1.254 ± 0.093
4.537GluAsn: 4.537 ± 0.167
1.387GluPro: 1.387 ± 0.086
3.591GluGln: 3.591 ± 0.175
1.396GluArg: 1.396 ± 0.09
2.675GluSer: 2.675 ± 0.111
4.311GluThr: 4.311 ± 0.141
3.077GluVal: 3.077 ± 0.135
0.323GluTrp: 0.323 ± 0.041
1.906GluTyr: 1.906 ± 0.124
0.0GluXaa: 0.0 ± 0.0
Phe
2.557PheAla: 2.557 ± 0.134
0.755PheCys: 0.755 ± 0.056
3.175PheAsp: 3.175 ± 0.127
3.092PheGlu: 3.092 ± 0.14
3.822PhePhe: 3.822 ± 0.179
2.239PheGly: 2.239 ± 0.106
1.107PheHis: 1.107 ± 0.075
4.801PheIle: 4.801 ± 0.166
4.659PheLys: 4.659 ± 0.167
7.628PheLeu: 7.628 ± 0.256
1.142PheMet: 1.142 ± 0.078
3.63PheAsn: 3.63 ± 0.148
1.583PhePro: 1.583 ± 0.092
2.964PheGln: 2.964 ± 0.141
1.475PheArg: 1.475 ± 0.089
3.836PheSer: 3.836 ± 0.132
2.293PheThr: 2.293 ± 0.105
2.984PheVal: 2.984 ± 0.15
0.519PheTrp: 0.519 ± 0.054
2.631PheTyr: 2.631 ± 0.125
0.005PheXaa: 0.005 ± 0.004
Gly
2.327GlyAla: 2.327 ± 0.109
0.299GlyCys: 0.299 ± 0.038
1.534GlyAsp: 1.534 ± 0.107
1.71GlyGlu: 1.71 ± 0.106
3.033GlyPhe: 3.033 ± 0.132
2.303GlyGly: 2.303 ± 0.136
0.926GlyHis: 0.926 ± 0.07
4.16GlyIle: 4.16 ± 0.138
4.723GlyLys: 4.723 ± 0.166
4.223GlyLeu: 4.223 ± 0.14
0.96GlyMet: 0.96 ± 0.072
2.254GlyAsn: 2.254 ± 0.103
1.009GlyPro: 1.009 ± 0.08
1.494GlyGln: 1.494 ± 0.081
1.323GlyArg: 1.323 ± 0.097
2.469GlySer: 2.469 ± 0.101
2.69GlyThr: 2.69 ± 0.113
2.553GlyVal: 2.553 ± 0.142
0.328GlyTrp: 0.328 ± 0.036
2.107GlyTyr: 2.107 ± 0.111
0.0GlyXaa: 0.0 ± 0.0
His
0.813HisAla: 0.813 ± 0.073
0.191HisCys: 0.191 ± 0.027
0.804HisAsp: 0.804 ± 0.067
1.068HisGlu: 1.068 ± 0.064
1.583HisPhe: 1.583 ± 0.103
0.833HisGly: 0.833 ± 0.075
0.652HisHis: 0.652 ± 0.068
1.45HisIle: 1.45 ± 0.086
1.769HisLys: 1.769 ± 0.118
2.871HisLeu: 2.871 ± 0.109
0.265HisMet: 0.265 ± 0.033
1.083HisAsn: 1.083 ± 0.076
0.97HisPro: 0.97 ± 0.073
1.612HisGln: 1.612 ± 0.091
0.549HisArg: 0.549 ± 0.058
1.088HisSer: 1.088 ± 0.077
1.083HisThr: 1.083 ± 0.07
0.715HisVal: 0.715 ± 0.06
0.098HisTrp: 0.098 ± 0.023
1.068HisTyr: 1.068 ± 0.071
0.0HisXaa: 0.0 ± 0.0
Ile
4.326IleAla: 4.326 ± 0.175
0.877IleCys: 0.877 ± 0.073
4.571IleAsp: 4.571 ± 0.163
5.144IleGlu: 5.144 ± 0.161
4.767IlePhe: 4.767 ± 0.192
3.689IleGly: 3.689 ± 0.138
1.475IleHis: 1.475 ± 0.091
8.78IleIle: 8.78 ± 0.232
10.45IleLys: 10.45 ± 0.252
8.981IleLeu: 8.981 ± 0.254
1.205IleMet: 1.205 ± 0.076
6.653IleAsn: 6.653 ± 0.187
3.136IlePro: 3.136 ± 0.124
3.552IleGln: 3.552 ± 0.15
2.229IleArg: 2.229 ± 0.124
5.13IleSer: 5.13 ± 0.158
5.918IleThr: 5.918 ± 0.177
4.16IleVal: 4.16 ± 0.147
0.446IleTrp: 0.446 ± 0.047
3.332IleTyr: 3.332 ± 0.153
0.0IleXaa: 0.0 ± 0.0
Lys
4.782LysAla: 4.782 ± 0.146
0.774LysCys: 0.774 ± 0.06
6.09LysAsp: 6.09 ± 0.233
9.025LysGlu: 9.025 ± 0.269
2.871LysPhe: 2.871 ± 0.112
4.248LysGly: 4.248 ± 0.177
2.288LysHis: 2.288 ± 0.103
10.695LysIle: 10.695 ± 0.265
12.121LysLys: 12.121 ± 0.281
9.5LysLeu: 9.5 ± 0.221
2.567LysMet: 2.567 ± 0.118
8.53LysAsn: 8.53 ± 0.209
3.165LysPro: 3.165 ± 0.12
5.923LysGln: 5.923 ± 0.211
2.842LysArg: 2.842 ± 0.139
4.321LysSer: 4.321 ± 0.147
8.545LysThr: 8.545 ± 0.237
4.836LysVal: 4.836 ± 0.157
0.534LysTrp: 0.534 ± 0.051
4.218LysTyr: 4.218 ± 0.15
0.005LysXaa: 0.005 ± 0.004
Leu
5.335LeuAla: 5.335 ± 0.186
1.112LeuCys: 1.112 ± 0.072
5.277LeuAsp: 5.277 ± 0.163
7.917LeuGlu: 7.917 ± 0.208
6.261LeuPhe: 6.261 ± 0.197
5.1LeuGly: 5.1 ± 0.161
1.847LeuHis: 1.847 ± 0.104
8.912LeuIle: 8.912 ± 0.225
12.503LeuLys: 12.503 ± 0.268
10.343LeuLeu: 10.343 ± 0.271
2.19LeuMet: 2.19 ± 0.118
7.094LeuAsn: 7.094 ± 0.225
3.165LeuPro: 3.165 ± 0.149
5.865LeuGln: 5.865 ± 0.202
2.675LeuArg: 2.675 ± 0.105
6.898LeuSer: 6.898 ± 0.196
6.31LeuThr: 6.31 ± 0.176
5.404LeuVal: 5.404 ± 0.175
0.681LeuTrp: 0.681 ± 0.061
3.493LeuTyr: 3.493 ± 0.143
0.0LeuXaa: 0.0 ± 0.0
Met
1.083MetAla: 1.083 ± 0.072
0.122MetCys: 0.122 ± 0.025
0.789MetAsp: 0.789 ± 0.064
1.073MetGlu: 1.073 ± 0.064
1.014MetPhe: 1.014 ± 0.069
0.97MetGly: 0.97 ± 0.063
0.328MetHis: 0.328 ± 0.038
1.68MetIle: 1.68 ± 0.106
2.092MetLys: 2.092 ± 0.1
1.774MetLeu: 1.774 ± 0.086
0.451MetMet: 0.451 ± 0.047
1.191MetAsn: 1.191 ± 0.084
0.691MetPro: 0.691 ± 0.058
1.249MetGln: 1.249 ± 0.085
0.421MetArg: 0.421 ± 0.041
1.112MetSer: 1.112 ± 0.079
1.083MetThr: 1.083 ± 0.07
0.784MetVal: 0.784 ± 0.066
0.206MetTrp: 0.206 ± 0.037
0.47MetTyr: 0.47 ± 0.045
0.0MetXaa: 0.0 ± 0.0
Asn
2.704AsnAla: 2.704 ± 0.109
0.715AsnCys: 0.715 ± 0.069
2.881AsnAsp: 2.881 ± 0.116
3.694AsnGlu: 3.694 ± 0.146
4.013AsnPhe: 4.013 ± 0.151
1.994AsnGly: 1.994 ± 0.108
1.872AsnHis: 1.872 ± 0.104
6.487AsnIle: 6.487 ± 0.215
7.354AsnLys: 7.354 ± 0.209
7.8AsnLeu: 7.8 ± 0.211
1.161AsnMet: 1.161 ± 0.079
6.394AsnAsn: 6.394 ± 0.275
3.591AsnPro: 3.591 ± 0.128
5.752AsnGln: 5.752 ± 0.222
1.489AsnArg: 1.489 ± 0.087
3.449AsnSer: 3.449 ± 0.129
2.91AsnThr: 2.91 ± 0.132
2.729AsnVal: 2.729 ± 0.128
0.431AsnTrp: 0.431 ± 0.05
3.361AsnTyr: 3.361 ± 0.154
0.0AsnXaa: 0.0 ± 0.0
Pro
0.931ProAla: 0.931 ± 0.073
0.49ProCys: 0.49 ± 0.053
1.244ProAsp: 1.244 ± 0.07
1.891ProGlu: 1.891 ± 0.094
2.126ProPhe: 2.126 ± 0.096
1.303ProGly: 1.303 ± 0.079
0.99ProHis: 0.99 ± 0.071
2.185ProIle: 2.185 ± 0.106
3.288ProLys: 3.288 ± 0.118
3.562ProLeu: 3.562 ± 0.153
0.563ProMet: 0.563 ± 0.06
2.504ProAsn: 2.504 ± 0.126
1.097ProPro: 1.097 ± 0.083
2.783ProGln: 2.783 ± 0.119
0.745ProArg: 0.745 ± 0.057
2.17ProSer: 2.17 ± 0.105
1.906ProThr: 1.906 ± 0.114
1.274ProVal: 1.274 ± 0.078
0.191ProTrp: 0.191 ± 0.028
1.387ProTyr: 1.387 ± 0.085
0.0ProXaa: 0.0 ± 0.0
Gln
2.749GlnAla: 2.749 ± 0.116
0.265GlnCys: 0.265 ± 0.037
2.264GlnAsp: 2.264 ± 0.103
5.154GlnGlu: 5.154 ± 0.202
1.857GlnPhe: 1.857 ± 0.085
2.273GlnGly: 2.273 ± 0.112
0.706GlnHis: 0.706 ± 0.055
5.732GlnIle: 5.732 ± 0.202
8.015GlnLys: 8.015 ± 0.233
5.61GlnLeu: 5.61 ± 0.189
1.083GlnMet: 1.083 ± 0.065
4.816GlnAsn: 4.816 ± 0.17
1.279GlnPro: 1.279 ± 0.097
3.836GlnGln: 3.836 ± 0.192
1.68GlnArg: 1.68 ± 0.095
2.313GlnSer: 2.313 ± 0.109
4.899GlnThr: 4.899 ± 0.207
2.352GlnVal: 2.352 ± 0.116
0.245GlnTrp: 0.245 ± 0.04
1.529GlnTyr: 1.529 ± 0.087
0.0GlnXaa: 0.0 ± 0.0
Arg
1.181ArgAla: 1.181 ± 0.084
0.25ArgCys: 0.25 ± 0.038
1.313ArgAsp: 1.313 ± 0.078
1.274ArgGlu: 1.274 ± 0.091
1.563ArgPhe: 1.563 ± 0.087
1.117ArgGly: 1.117 ± 0.083
0.696ArgHis: 0.696 ± 0.057
2.557ArgIle: 2.557 ± 0.112
3.062ArgLys: 3.062 ± 0.119
2.396ArgLeu: 2.396 ± 0.115
0.48ArgMet: 0.48 ± 0.054
1.671ArgAsn: 1.671 ± 0.086
0.985ArgPro: 0.985 ± 0.074
1.494ArgGln: 1.494 ± 0.077
0.955ArgArg: 0.955 ± 0.084
1.338ArgSer: 1.338 ± 0.077
1.391ArgThr: 1.391 ± 0.101
1.293ArgVal: 1.293 ± 0.089
0.211ArgTrp: 0.211 ± 0.031
1.191ArgTyr: 1.191 ± 0.077
0.0ArgXaa: 0.0 ± 0.0
Ser
1.832SerAla: 1.832 ± 0.084
0.862SerCys: 0.862 ± 0.071
2.602SerAsp: 2.602 ± 0.099
2.66SerGlu: 2.66 ± 0.143
4.419SerPhe: 4.419 ± 0.188
2.636SerGly: 2.636 ± 0.146
1.347SerHis: 1.347 ± 0.094
3.846SerIle: 3.846 ± 0.134
5.404SerLys: 5.404 ± 0.165
6.663SerLeu: 6.663 ± 0.183
0.926SerMet: 0.926 ± 0.065
3.724SerAsn: 3.724 ± 0.142
1.705SerPro: 1.705 ± 0.092
3.675SerGln: 3.675 ± 0.134
1.607SerArg: 1.607 ± 0.099
3.322SerSer: 3.322 ± 0.153
2.317SerThr: 2.317 ± 0.1
2.234SerVal: 2.234 ± 0.094
0.353SerTrp: 0.353 ± 0.041
2.278SerTyr: 2.278 ± 0.107
0.0SerXaa: 0.0 ± 0.0
Thr
2.278ThrAla: 2.278 ± 0.093
0.524ThrCys: 0.524 ± 0.057
2.112ThrAsp: 2.112 ± 0.108
2.425ThrGlu: 2.425 ± 0.129
3.679ThrPhe: 3.679 ± 0.156
2.366ThrGly: 2.366 ± 0.111
1.494ThrHis: 1.494 ± 0.077
4.983ThrIle: 4.983 ± 0.188
7.006ThrLys: 7.006 ± 0.214
6.742ThrLeu: 6.742 ± 0.16
0.794ThrMet: 0.794 ± 0.064
4.684ThrAsn: 4.684 ± 0.185
2.925ThrPro: 2.925 ± 0.131
3.782ThrGln: 3.782 ± 0.166
1.436ThrArg: 1.436 ± 0.099
2.959ThrSer: 2.959 ± 0.119
4.013ThrThr: 4.013 ± 0.153
2.043ThrVal: 2.043 ± 0.109
0.328ThrTrp: 0.328 ± 0.048
2.264ThrTyr: 2.264 ± 0.114
0.0ThrXaa: 0.0 ± 0.0
Val
2.641ValAla: 2.641 ± 0.135
0.706ValCys: 0.706 ± 0.063
2.322ValAsp: 2.322 ± 0.128
2.386ValGlu: 2.386 ± 0.112
3.253ValPhe: 3.253 ± 0.154
2.513ValGly: 2.513 ± 0.121
0.637ValHis: 0.637 ± 0.055
4.375ValIle: 4.375 ± 0.161
3.822ValLys: 3.822 ± 0.125
5.556ValLeu: 5.556 ± 0.173
0.946ValMet: 0.946 ± 0.072
2.567ValAsn: 2.567 ± 0.121
1.421ValPro: 1.421 ± 0.091
1.578ValGln: 1.578 ± 0.099
1.323ValArg: 1.323 ± 0.073
3.131ValSer: 3.131 ± 0.131
2.028ValThr: 2.028 ± 0.108
3.219ValVal: 3.219 ± 0.157
0.451ValTrp: 0.451 ± 0.041
1.911ValTyr: 1.911 ± 0.094
0.0ValXaa: 0.0 ± 0.0
Trp
0.299TrpAla: 0.299 ± 0.027
0.064TrpCys: 0.064 ± 0.016
0.309TrpAsp: 0.309 ± 0.047
0.363TrpGlu: 0.363 ± 0.052
0.514TrpPhe: 0.514 ± 0.048
0.309TrpGly: 0.309 ± 0.037
0.206TrpHis: 0.206 ± 0.031
0.397TrpIle: 0.397 ± 0.046
0.505TrpLys: 0.505 ± 0.049
0.794TrpLeu: 0.794 ± 0.065
0.152TrpMet: 0.152 ± 0.028
0.539TrpAsn: 0.539 ± 0.054
0.142TrpPro: 0.142 ± 0.03
0.519TrpGln: 0.519 ± 0.05
0.176TrpArg: 0.176 ± 0.028
0.235TrpSer: 0.235 ± 0.034
0.216TrpThr: 0.216 ± 0.036
0.309TrpVal: 0.309 ± 0.039
0.064TrpTrp: 0.064 ± 0.02
0.294TrpTyr: 0.294 ± 0.038
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.573TyrAla: 1.573 ± 0.087
0.534TyrCys: 0.534 ± 0.054
2.342TyrAsp: 2.342 ± 0.105
2.077TyrGlu: 2.077 ± 0.107
2.773TyrPhe: 2.773 ± 0.122
1.509TyrGly: 1.509 ± 0.084
1.333TyrHis: 1.333 ± 0.098
2.66TyrIle: 2.66 ± 0.121
2.7TyrLys: 2.7 ± 0.115
5.242TyrLeu: 5.242 ± 0.181
0.725TyrMet: 0.725 ± 0.067
2.626TyrAsn: 2.626 ± 0.127
1.034TyrPro: 1.034 ± 0.069
3.63TyrGln: 3.63 ± 0.189
1.352TyrArg: 1.352 ± 0.08
2.112TyrSer: 2.112 ± 0.117
1.641TyrThr: 1.641 ± 0.087
1.578TyrVal: 1.578 ± 0.087
0.392TyrTrp: 0.392 ± 0.043
2.112TyrTyr: 2.112 ± 0.116
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.01XaaThr: 0.01 ± 0.009
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 730 proteins (204107 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski