Amino acid dipepetide frequency for Hubei sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.407AlaAla: 12.407 ± 4.604
1.654AlaCys: 1.654 ± 0.71
3.309AlaAsp: 3.309 ± 2.301
4.136AlaGlu: 4.136 ± 1.859
4.963AlaPhe: 4.963 ± 1.266
8.271AlaGly: 8.271 ± 2.941
0.0AlaHis: 0.0 ± 0.0
1.654AlaIle: 1.654 ± 0.683
4.136AlaLys: 4.136 ± 1.166
9.926AlaLeu: 9.926 ± 1.441
4.136AlaMet: 4.136 ± 1.671
1.654AlaAsn: 1.654 ± 0.71
4.963AlaPro: 4.963 ± 1.632
3.309AlaGln: 3.309 ± 1.693
5.79AlaArg: 5.79 ± 2.155
13.234AlaSer: 13.234 ± 3.727
7.444AlaThr: 7.444 ± 2.172
5.79AlaVal: 5.79 ± 1.164
2.481AlaTrp: 2.481 ± 1.369
0.827AlaTyr: 0.827 ± 0.763
0.0AlaXaa: 0.0 ± 0.0
Cys
1.654CysAla: 1.654 ± 0.846
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.827CysGlu: 0.827 ± 0.528
0.827CysPhe: 0.827 ± 0.528
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.827CysLys: 0.827 ± 0.528
0.827CysLeu: 0.827 ± 0.763
1.654CysMet: 1.654 ± 0.846
0.0CysAsn: 0.0 ± 0.0
0.827CysPro: 0.827 ± 0.851
0.827CysGln: 0.827 ± 0.851
0.0CysArg: 0.0 ± 0.0
0.827CysSer: 0.827 ± 0.851
0.0CysThr: 0.0 ± 0.0
1.654CysVal: 1.654 ± 1.055
0.0CysTrp: 0.0 ± 0.0
0.827CysTyr: 0.827 ± 0.851
0.0CysXaa: 0.0 ± 0.0
Asp
3.309AspAla: 3.309 ± 2.048
0.0AspCys: 0.0 ± 0.0
6.617AspAsp: 6.617 ± 2.506
3.309AspGlu: 3.309 ± 0.93
1.654AspPhe: 1.654 ± 0.71
4.136AspGly: 4.136 ± 1.859
0.0AspHis: 0.0 ± 0.0
3.309AspIle: 3.309 ± 1.693
1.654AspLys: 1.654 ± 0.683
4.136AspLeu: 4.136 ± 1.996
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
3.309AspPro: 3.309 ± 0.214
2.481AspGln: 2.481 ± 1.348
0.0AspArg: 0.0 ± 0.0
1.654AspSer: 1.654 ± 0.846
0.0AspThr: 0.0 ± 0.0
2.481AspVal: 2.481 ± 0.918
1.654AspTrp: 1.654 ± 0.846
1.654AspTyr: 1.654 ± 0.683
0.0AspXaa: 0.0 ± 0.0
Glu
1.654GluAla: 1.654 ± 1.055
0.0GluCys: 0.0 ± 0.0
1.654GluAsp: 1.654 ± 0.683
4.136GluGlu: 4.136 ± 1.671
0.827GluPhe: 0.827 ± 0.763
4.136GluGly: 4.136 ± 1.671
0.0GluHis: 0.0 ± 0.0
1.654GluIle: 1.654 ± 0.846
2.481GluLys: 2.481 ± 0.952
10.753GluLeu: 10.753 ± 3.549
0.827GluMet: 0.827 ± 0.528
3.309GluAsn: 3.309 ± 0.214
1.654GluPro: 1.654 ± 0.683
3.309GluGln: 3.309 ± 1.365
2.481GluArg: 2.481 ± 1.369
2.481GluSer: 2.481 ± 0.918
4.136GluThr: 4.136 ± 1.57
5.79GluVal: 5.79 ± 1.164
0.0GluTrp: 0.0 ± 0.0
3.309GluTyr: 3.309 ± 1.38
0.0GluXaa: 0.0 ± 0.0
Phe
4.136PheAla: 4.136 ± 1.554
1.654PheCys: 1.654 ± 0.846
2.481PheAsp: 2.481 ± 1.348
3.309PheGlu: 3.309 ± 1.318
0.0PhePhe: 0.0 ± 0.0
2.481PheGly: 2.481 ± 1.475
0.0PheHis: 0.0 ± 0.0
0.827PheIle: 0.827 ± 0.851
0.0PheLys: 0.0 ± 0.0
1.654PheLeu: 1.654 ± 0.71
0.827PheMet: 0.827 ± 0.851
0.827PheAsn: 0.827 ± 0.528
4.136PhePro: 4.136 ± 1.554
1.654PheGln: 1.654 ± 1.055
1.654PheArg: 1.654 ± 1.055
3.309PheSer: 3.309 ± 0.93
0.827PheThr: 0.827 ± 0.851
4.963PheVal: 4.963 ± 1.904
0.0PheTrp: 0.0 ± 0.0
0.827PheTyr: 0.827 ± 0.528
0.0PheXaa: 0.0 ± 0.0
Gly
6.617GlyAla: 6.617 ± 2.178
0.827GlyCys: 0.827 ± 0.528
2.481GlyAsp: 2.481 ± 1.369
0.827GlyGlu: 0.827 ± 0.528
9.098GlyPhe: 9.098 ± 1.502
9.098GlyGly: 9.098 ± 0.963
0.0GlyHis: 0.0 ± 0.0
5.79GlyIle: 5.79 ± 1.473
4.136GlyLys: 4.136 ± 1.785
5.79GlyLeu: 5.79 ± 1.164
1.654GlyMet: 1.654 ± 0.683
1.654GlyAsn: 1.654 ± 1.701
0.827GlyPro: 0.827 ± 0.528
0.827GlyGln: 0.827 ± 0.851
4.136GlyArg: 4.136 ± 1.671
13.234GlySer: 13.234 ± 3.039
5.79GlyThr: 5.79 ± 3.771
5.79GlyVal: 5.79 ± 1.362
0.827GlyTrp: 0.827 ± 0.763
3.309GlyTyr: 3.309 ± 0.93
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.654HisGlu: 1.654 ± 1.526
0.0HisPhe: 0.0 ± 0.0
0.827HisGly: 0.827 ± 0.528
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.827HisLys: 0.827 ± 0.763
0.827HisLeu: 0.827 ± 0.528
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.827HisPro: 0.827 ± 0.528
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.481HisSer: 2.481 ± 1.348
0.827HisThr: 0.827 ± 0.528
3.309HisVal: 3.309 ± 0.214
0.827HisTrp: 0.827 ± 0.763
0.827HisTyr: 0.827 ± 0.528
0.0HisXaa: 0.0 ± 0.0
Ile
4.136IleAla: 4.136 ± 0.739
0.827IleCys: 0.827 ± 0.851
0.827IleAsp: 0.827 ± 0.528
3.309IleGlu: 3.309 ± 0.93
2.481IlePhe: 2.481 ± 1.475
4.136IleGly: 4.136 ± 1.785
1.654IleHis: 1.654 ± 1.055
0.0IleIle: 0.0 ± 0.0
1.654IleLys: 1.654 ± 0.71
4.136IleLeu: 4.136 ± 1.785
2.481IleMet: 2.481 ± 0.405
1.654IleAsn: 1.654 ± 1.701
4.136IlePro: 4.136 ± 0.739
1.654IleGln: 1.654 ± 1.526
4.963IleArg: 4.963 ± 1.817
4.136IleSer: 4.136 ± 2.144
1.654IleThr: 1.654 ± 1.055
2.481IleVal: 2.481 ± 0.952
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
8.271LysAla: 8.271 ± 3.115
0.827LysCys: 0.827 ± 0.528
0.0LysAsp: 0.0 ± 0.0
2.481LysGlu: 2.481 ± 1.348
0.827LysPhe: 0.827 ± 0.528
1.654LysGly: 1.654 ± 0.71
0.827LysHis: 0.827 ± 0.763
2.481LysIle: 2.481 ± 1.475
3.309LysLys: 3.309 ± 1.42
3.309LysLeu: 3.309 ± 0.214
1.654LysMet: 1.654 ± 1.321
0.827LysAsn: 0.827 ± 0.763
4.963LysPro: 4.963 ± 1.904
2.481LysGln: 2.481 ± 0.321
1.654LysArg: 1.654 ± 0.683
1.654LysSer: 1.654 ± 0.683
0.827LysThr: 0.827 ± 0.528
4.963LysVal: 4.963 ± 2.36
1.654LysTrp: 1.654 ± 0.846
1.654LysTyr: 1.654 ± 1.055
0.0LysXaa: 0.0 ± 0.0
Leu
5.79LeuAla: 5.79 ± 0.138
0.0LeuCys: 0.0 ± 0.0
4.963LeuAsp: 4.963 ± 1.395
8.271LeuGlu: 8.271 ± 3.992
3.309LeuPhe: 3.309 ± 0.214
7.444LeuGly: 7.444 ± 0.581
2.481LeuHis: 2.481 ± 1.348
4.136LeuIle: 4.136 ± 0.739
7.444LeuLys: 7.444 ± 2.043
9.926LeuLeu: 9.926 ± 1.441
0.827LeuMet: 0.827 ± 0.851
1.654LeuAsn: 1.654 ± 0.846
3.309LeuPro: 3.309 ± 2.11
2.481LeuGln: 2.481 ± 0.321
7.444LeuArg: 7.444 ± 3.678
5.79LeuSer: 5.79 ± 0.138
4.136LeuThr: 4.136 ± 4.253
4.963LeuVal: 4.963 ± 2.696
0.0LeuTrp: 0.0 ± 0.0
0.827LeuTyr: 0.827 ± 0.528
0.0LeuXaa: 0.0 ± 0.0
Met
4.136MetAla: 4.136 ± 1.859
0.827MetCys: 0.827 ± 0.851
0.0MetAsp: 0.0 ± 0.0
0.827MetGlu: 0.827 ± 0.763
0.0MetPhe: 0.0 ± 0.0
1.654MetGly: 1.654 ± 1.526
0.0MetHis: 0.0 ± 0.0
1.654MetIle: 1.654 ± 1.055
0.0MetLys: 0.0 ± 0.0
1.654MetLeu: 1.654 ± 0.683
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.827MetPro: 0.827 ± 0.851
0.827MetGln: 0.827 ± 0.851
2.481MetArg: 2.481 ± 1.369
2.481MetSer: 2.481 ± 1.369
0.827MetThr: 0.827 ± 0.528
4.963MetVal: 4.963 ± 1.632
0.0MetTrp: 0.0 ± 0.0
1.654MetTyr: 1.654 ± 0.71
0.0MetXaa: 0.0 ± 0.0
Asn
4.136AsnAla: 4.136 ± 1.928
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.654AsnGlu: 1.654 ± 0.683
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.654AsnIle: 1.654 ± 0.71
0.827AsnLys: 0.827 ± 0.763
0.827AsnLeu: 0.827 ± 0.528
0.0AsnMet: 0.0 ± 0.0
0.827AsnAsn: 0.827 ± 0.851
0.827AsnPro: 0.827 ± 0.528
0.827AsnGln: 0.827 ± 0.763
2.481AsnArg: 2.481 ± 1.475
3.309AsnSer: 3.309 ± 1.693
5.79AsnThr: 5.79 ± 4.805
1.654AsnVal: 1.654 ± 0.71
0.0AsnTrp: 0.0 ± 0.0
0.827AsnTyr: 0.827 ± 0.763
0.0AsnXaa: 0.0 ± 0.0
Pro
4.136ProAla: 4.136 ± 1.785
1.654ProCys: 1.654 ± 1.701
0.827ProAsp: 0.827 ± 0.528
1.654ProGlu: 1.654 ± 1.055
0.0ProPhe: 0.0 ± 0.0
5.79ProGly: 5.79 ± 2.586
0.827ProHis: 0.827 ± 0.528
4.963ProIle: 4.963 ± 3.166
3.309ProLys: 3.309 ± 2.11
4.963ProLeu: 4.963 ± 0.797
0.827ProMet: 0.827 ± 0.528
0.827ProAsn: 0.827 ± 0.763
3.309ProPro: 3.309 ± 2.11
2.481ProGln: 2.481 ± 1.369
3.309ProArg: 3.309 ± 1.318
6.617ProSer: 6.617 ± 4.221
5.79ProThr: 5.79 ± 1.473
4.963ProVal: 4.963 ± 0.797
0.827ProTrp: 0.827 ± 0.528
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.654GlnAla: 1.654 ± 0.846
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.827GlnGlu: 0.827 ± 0.763
0.827GlnPhe: 0.827 ± 0.528
4.136GlnGly: 4.136 ± 0.739
2.481GlnHis: 2.481 ± 0.321
1.654GlnIle: 1.654 ± 0.846
0.827GlnLys: 0.827 ± 0.763
3.309GlnLeu: 3.309 ± 3.052
0.0GlnMet: 0.0 ± 0.0
0.827GlnAsn: 0.827 ± 0.763
2.481GlnPro: 2.481 ± 0.918
0.827GlnGln: 0.827 ± 0.528
3.309GlnArg: 3.309 ± 1.42
1.654GlnSer: 1.654 ± 0.846
0.0GlnThr: 0.0 ± 0.0
3.309GlnVal: 3.309 ± 1.089
0.827GlnTrp: 0.827 ± 0.763
0.827GlnTyr: 0.827 ± 0.528
0.0GlnXaa: 0.0 ± 0.0
Arg
9.098ArgAla: 9.098 ± 3.033
0.827ArgCys: 0.827 ± 0.528
4.136ArgAsp: 4.136 ± 1.671
0.0ArgGlu: 0.0 ± 0.0
2.481ArgPhe: 2.481 ± 0.918
2.481ArgGly: 2.481 ± 1.583
0.827ArgHis: 0.827 ± 0.763
4.136ArgIle: 4.136 ± 1.671
3.309ArgLys: 3.309 ± 1.089
4.136ArgLeu: 4.136 ± 1.671
4.136ArgMet: 4.136 ± 0.817
3.309ArgAsn: 3.309 ± 1.42
2.481ArgPro: 2.481 ± 0.321
0.827ArgGln: 0.827 ± 0.528
4.136ArgArg: 4.136 ± 0.739
3.309ArgSer: 3.309 ± 1.42
1.654ArgThr: 1.654 ± 0.846
8.271ArgVal: 8.271 ± 4.44
0.0ArgTrp: 0.0 ± 0.0
0.827ArgTyr: 0.827 ± 0.763
0.0ArgXaa: 0.0 ± 0.0
Ser
7.444SerAla: 7.444 ± 0.795
0.0SerCys: 0.0 ± 0.0
6.617SerAsp: 6.617 ± 0.753
4.136SerGlu: 4.136 ± 0.739
3.309SerPhe: 3.309 ± 1.318
14.061SerGly: 14.061 ± 1.789
0.827SerHis: 0.827 ± 0.528
4.963SerIle: 4.963 ± 1.266
4.136SerLys: 4.136 ± 1.57
4.963SerLeu: 4.963 ± 0.721
0.827SerMet: 0.827 ± 0.528
1.654SerAsn: 1.654 ± 1.701
6.617SerPro: 6.617 ± 4.221
0.827SerGln: 0.827 ± 0.763
8.271SerArg: 8.271 ± 3.141
15.715SerSer: 15.715 ± 6.451
5.79SerThr: 5.79 ± 1.473
7.444SerVal: 7.444 ± 0.962
0.0SerTrp: 0.0 ± 0.0
3.309SerTyr: 3.309 ± 1.089
0.0SerXaa: 0.0 ± 0.0
Thr
3.309ThrAla: 3.309 ± 0.214
0.827ThrCys: 0.827 ± 0.763
1.654ThrAsp: 1.654 ± 0.846
2.481ThrGlu: 2.481 ± 1.475
0.827ThrPhe: 0.827 ± 0.851
4.963ThrGly: 4.963 ± 3.984
0.0ThrHis: 0.0 ± 0.0
4.136ThrIle: 4.136 ± 0.795
0.827ThrLys: 0.827 ± 0.528
2.481ThrLeu: 2.481 ± 1.475
1.654ThrMet: 1.654 ± 0.71
4.963ThrAsn: 4.963 ± 1.817
3.309ThrPro: 3.309 ± 1.42
2.481ThrGln: 2.481 ± 0.918
0.827ThrArg: 0.827 ± 0.528
7.444ThrSer: 7.444 ± 1.688
3.309ThrThr: 3.309 ± 0.93
4.963ThrVal: 4.963 ± 2.13
0.827ThrTrp: 0.827 ± 0.763
2.481ThrTyr: 2.481 ± 0.918
0.0ThrXaa: 0.0 ± 0.0
Val
13.234ValAla: 13.234 ± 2.257
1.654ValCys: 1.654 ± 0.683
3.309ValAsp: 3.309 ± 1.365
5.79ValGlu: 5.79 ± 1.164
2.481ValPhe: 2.481 ± 1.348
4.963ValGly: 4.963 ± 2.774
2.481ValHis: 2.481 ± 1.348
2.481ValIle: 2.481 ± 0.952
4.136ValLys: 4.136 ± 0.643
9.098ValLeu: 9.098 ± 1.502
2.481ValMet: 2.481 ± 0.321
0.827ValAsn: 0.827 ± 0.851
4.136ValPro: 4.136 ± 1.859
0.827ValGln: 0.827 ± 0.851
5.79ValArg: 5.79 ± 2.012
9.926ValSer: 9.926 ± 2.926
2.481ValThr: 2.481 ± 1.583
10.753ValVal: 10.753 ± 1.164
1.654ValTrp: 1.654 ± 0.683
2.481ValTyr: 2.481 ± 0.918
0.0ValXaa: 0.0 ± 0.0
Trp
3.309TrpAla: 3.309 ± 0.93
0.0TrpCys: 0.0 ± 0.0
0.827TrpAsp: 0.827 ± 0.763
0.827TrpGlu: 0.827 ± 0.763
0.827TrpPhe: 0.827 ± 0.851
0.827TrpGly: 0.827 ± 0.763
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.654TrpLeu: 1.654 ± 1.526
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.827TrpGln: 0.827 ± 0.528
0.827TrpArg: 0.827 ± 0.528
1.654TrpSer: 1.654 ± 1.526
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.827TrpTyr: 0.827 ± 0.851
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.654TyrAla: 1.654 ± 0.683
0.0TyrCys: 0.0 ± 0.0
1.654TyrAsp: 1.654 ± 1.055
4.136TyrGlu: 4.136 ± 1.671
0.827TyrPhe: 0.827 ± 0.528
1.654TyrGly: 1.654 ± 0.683
0.827TyrHis: 0.827 ± 0.528
0.827TyrIle: 0.827 ± 0.851
2.481TyrLys: 2.481 ± 0.918
0.827TyrLeu: 0.827 ± 0.528
0.0TyrMet: 0.0 ± 0.0
0.827TyrAsn: 0.827 ± 0.763
4.136TyrPro: 4.136 ± 2.154
0.0TyrGln: 0.0 ± 0.0
1.654TyrArg: 1.654 ± 0.846
0.0TyrSer: 0.0 ± 0.0
2.481TyrThr: 2.481 ± 0.952
2.481TyrVal: 2.481 ± 0.918
0.827TyrTrp: 0.827 ± 0.528
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1210 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski