Amino acid dipepetide frequency for Arrabida virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.303AlaAla: 6.303 ± 2.864
0.525AlaCys: 0.525 ± 0.278
2.626AlaAsp: 2.626 ± 1.668
5.777AlaGlu: 5.777 ± 2.12
2.626AlaPhe: 2.626 ± 1.488
2.101AlaGly: 2.101 ± 1.915
1.05AlaHis: 1.05 ± 0.808
5.777AlaIle: 5.777 ± 1.689
3.151AlaLys: 3.151 ± 1.405
5.252AlaLeu: 5.252 ± 2.846
2.101AlaMet: 2.101 ± 1.615
1.576AlaAsn: 1.576 ± 0.835
2.626AlaPro: 2.626 ± 0.753
1.576AlaGln: 1.576 ± 0.559
4.202AlaArg: 4.202 ± 1.204
5.777AlaSer: 5.777 ± 2.278
5.252AlaThr: 5.252 ± 0.927
2.101AlaVal: 2.101 ± 1.113
1.576AlaTrp: 1.576 ± 0.703
0.525AlaTyr: 0.525 ± 0.983
0.0AlaXaa: 0.0 ± 0.0
Cys
1.576CysAla: 1.576 ± 0.703
0.525CysCys: 0.525 ± 0.278
2.626CysAsp: 2.626 ± 0.753
0.0CysGlu: 0.0 ± 0.0
1.576CysPhe: 1.576 ± 0.835
0.525CysGly: 0.525 ± 0.278
1.576CysHis: 1.576 ± 0.835
1.576CysIle: 1.576 ± 0.559
2.626CysLys: 2.626 ± 1.391
4.202CysLeu: 4.202 ± 2.226
1.05CysMet: 1.05 ± 0.808
1.05CysAsn: 1.05 ± 0.557
1.576CysPro: 1.576 ± 0.835
1.05CysGln: 1.05 ± 0.557
0.525CysArg: 0.525 ± 0.278
2.626CysSer: 2.626 ± 1.391
3.151CysThr: 3.151 ± 1.67
2.626CysVal: 2.626 ± 1.391
0.0CysTrp: 0.0 ± 0.0
1.576CysTyr: 1.576 ± 0.559
0.0CysXaa: 0.0 ± 0.0
Asp
1.05AspAla: 1.05 ± 0.808
3.676AspCys: 3.676 ± 1.948
2.626AspAsp: 2.626 ± 0.801
2.626AspGlu: 2.626 ± 1.488
2.626AspPhe: 2.626 ± 1.176
0.525AspGly: 0.525 ± 0.278
0.0AspHis: 0.0 ± 0.0
3.151AspIle: 3.151 ± 1.939
2.101AspLys: 2.101 ± 0.7
4.202AspLeu: 4.202 ± 1.026
1.05AspMet: 1.05 ± 0.557
2.101AspAsn: 2.101 ± 0.7
1.576AspPro: 1.576 ± 0.703
1.576AspGln: 1.576 ± 0.559
1.576AspArg: 1.576 ± 0.559
7.878AspSer: 7.878 ± 0.53
3.676AspThr: 3.676 ± 1.187
4.202AspVal: 4.202 ± 0.675
1.576AspTrp: 1.576 ± 1.038
1.576AspTyr: 1.576 ± 1.454
0.0AspXaa: 0.0 ± 0.0
Glu
3.151GluAla: 3.151 ± 1.118
2.101GluCys: 2.101 ± 1.113
4.727GluAsp: 4.727 ± 1.253
3.676GluGlu: 3.676 ± 1.2
3.151GluPhe: 3.151 ± 2.959
3.676GluGly: 3.676 ± 0.155
0.525GluHis: 0.525 ± 0.278
2.626GluIle: 2.626 ± 0.801
6.828GluLys: 6.828 ± 2.494
4.202GluLeu: 4.202 ± 0.384
3.676GluMet: 3.676 ± 1.128
1.05GluAsn: 1.05 ± 0.557
1.576GluPro: 1.576 ± 0.835
1.05GluGln: 1.05 ± 0.557
5.777GluArg: 5.777 ± 2.191
5.252GluSer: 5.252 ± 2.148
1.576GluThr: 1.576 ± 0.559
4.202GluVal: 4.202 ± 1.453
0.0GluTrp: 0.0 ± 0.0
2.101GluTyr: 2.101 ± 1.113
0.0GluXaa: 0.0 ± 0.0
Phe
2.101PheAla: 2.101 ± 1.615
2.101PheCys: 2.101 ± 1.113
2.101PheAsp: 2.101 ± 0.763
2.626PheGlu: 2.626 ± 0.491
3.151PhePhe: 3.151 ± 0.235
1.576PheGly: 1.576 ± 1.454
0.0PheHis: 0.0 ± 0.0
4.202PheIle: 4.202 ± 1.204
1.576PheLys: 1.576 ± 0.835
4.202PheLeu: 4.202 ± 0.675
2.626PheMet: 2.626 ± 0.491
1.576PheAsn: 1.576 ± 0.559
0.525PhePro: 0.525 ± 0.823
0.525PheGln: 0.525 ± 0.278
1.05PheArg: 1.05 ± 0.646
3.151PheSer: 3.151 ± 0.235
3.151PheThr: 3.151 ± 0.235
2.626PheVal: 2.626 ± 0.491
1.576PheTrp: 1.576 ± 0.559
1.576PheTyr: 1.576 ± 0.559
0.0PheXaa: 0.0 ± 0.0
Gly
4.202GlyAla: 4.202 ± 1.026
1.05GlyCys: 1.05 ± 0.557
3.676GlyAsp: 3.676 ± 1.2
3.676GlyGlu: 3.676 ± 1.128
2.101GlyPhe: 2.101 ± 0.7
4.202GlyGly: 4.202 ± 1.453
0.525GlyHis: 0.525 ± 0.278
2.626GlyIle: 2.626 ± 0.801
2.626GlyLys: 2.626 ± 0.801
4.727GlyLeu: 4.727 ± 0.653
0.525GlyMet: 0.525 ± 0.823
2.626GlyAsn: 2.626 ± 1.488
3.151GlyPro: 3.151 ± 0.963
1.05GlyGln: 1.05 ± 0.557
3.151GlyArg: 3.151 ± 2.629
6.303GlySer: 6.303 ± 2.517
3.151GlyThr: 3.151 ± 2.423
4.202GlyVal: 4.202 ± 0.384
1.05GlyTrp: 1.05 ± 0.557
1.05GlyTyr: 1.05 ± 0.557
0.0GlyXaa: 0.0 ± 0.0
His
0.525HisAla: 0.525 ± 0.823
1.576HisCys: 1.576 ± 0.835
1.05HisAsp: 1.05 ± 0.557
1.05HisGlu: 1.05 ± 0.557
1.576HisPhe: 1.576 ± 0.835
2.101HisGly: 2.101 ± 0.7
0.0HisHis: 0.0 ± 0.0
0.525HisIle: 0.525 ± 0.278
1.576HisLys: 1.576 ± 0.835
1.576HisLeu: 1.576 ± 0.559
0.525HisMet: 0.525 ± 0.278
0.0HisAsn: 0.0 ± 0.0
1.05HisPro: 1.05 ± 0.808
1.05HisGln: 1.05 ± 0.646
0.525HisArg: 0.525 ± 0.278
3.151HisSer: 3.151 ± 0.963
1.05HisThr: 1.05 ± 0.557
0.525HisVal: 0.525 ± 0.278
0.0HisTrp: 0.0 ± 0.0
0.525HisTyr: 0.525 ± 0.823
0.0HisXaa: 0.0 ± 0.0
Ile
4.202IleAla: 4.202 ± 3.23
1.576IleCys: 1.576 ± 0.559
1.576IleAsp: 1.576 ± 1.038
3.676IleGlu: 3.676 ± 0.155
1.576IlePhe: 1.576 ± 0.559
5.252IleGly: 5.252 ± 1.929
1.05IleHis: 1.05 ± 0.646
6.303IleIle: 6.303 ± 1.026
6.303IleLys: 6.303 ± 1.806
5.777IleLeu: 5.777 ± 1.706
1.05IleMet: 1.05 ± 0.646
2.626IleAsn: 2.626 ± 1.668
0.525IlePro: 0.525 ± 0.278
1.576IleGln: 1.576 ± 0.559
3.676IleArg: 3.676 ± 1.2
3.151IleSer: 3.151 ± 0.974
5.252IleThr: 5.252 ± 1.929
4.727IleVal: 4.727 ± 2.108
0.525IleTrp: 0.525 ± 0.278
2.101IleTyr: 2.101 ± 1.292
0.0IleXaa: 0.0 ± 0.0
Lys
4.202LysAla: 4.202 ± 0.384
2.626LysCys: 2.626 ± 0.801
1.576LysAsp: 1.576 ± 0.703
4.727LysGlu: 4.727 ± 1.479
2.626LysPhe: 2.626 ± 0.753
3.676LysGly: 3.676 ± 1.214
2.101LysHis: 2.101 ± 1.292
3.151LysIle: 3.151 ± 1.118
7.353LysLys: 7.353 ± 2.428
6.303LysLeu: 6.303 ± 1.026
3.151LysMet: 3.151 ± 2.481
3.151LysAsn: 3.151 ± 1.118
4.727LysPro: 4.727 ± 1.479
3.676LysGln: 3.676 ± 0.155
4.727LysArg: 4.727 ± 1.497
5.252LysSer: 5.252 ± 1.506
3.676LysThr: 3.676 ± 1.214
4.202LysVal: 4.202 ± 1.4
1.05LysTrp: 1.05 ± 0.557
3.676LysTyr: 3.676 ± 1.187
0.0LysXaa: 0.0 ± 0.0
Leu
7.353LeuAla: 7.353 ± 1.815
1.576LeuCys: 1.576 ± 0.835
3.151LeuAsp: 3.151 ± 1.405
5.252LeuGlu: 5.252 ± 0.982
1.05LeuPhe: 1.05 ± 1.315
4.202LeuGly: 4.202 ± 2.226
1.05LeuHis: 1.05 ± 0.557
4.727LeuIle: 4.727 ± 0.886
6.828LeuLys: 6.828 ± 1.125
9.454LeuLeu: 9.454 ± 1.616
3.676LeuMet: 3.676 ± 1.065
3.151LeuAsn: 3.151 ± 1.161
3.676LeuPro: 3.676 ± 1.801
1.05LeuGln: 1.05 ± 0.646
4.727LeuArg: 4.727 ± 1.497
8.929LeuSer: 8.929 ± 2.172
5.252LeuThr: 5.252 ± 1.978
5.252LeuVal: 5.252 ± 2.148
0.525LeuTrp: 0.525 ± 0.278
2.101LeuTyr: 2.101 ± 1.292
0.0LeuXaa: 0.0 ± 0.0
Met
4.727MetAla: 4.727 ± 0.491
0.525MetCys: 0.525 ± 0.278
1.576MetAsp: 1.576 ± 0.703
0.525MetGlu: 0.525 ± 0.278
2.101MetPhe: 2.101 ± 1.113
1.05MetGly: 1.05 ± 0.557
1.05MetHis: 1.05 ± 0.808
2.101MetIle: 2.101 ± 1.691
3.151MetLys: 3.151 ± 1.432
1.576MetLeu: 1.576 ± 2.17
2.626MetMet: 2.626 ± 2.58
1.05MetAsn: 1.05 ± 0.646
0.525MetPro: 0.525 ± 0.278
1.05MetGln: 1.05 ± 0.557
1.05MetArg: 1.05 ± 0.646
3.676MetSer: 3.676 ± 1.214
2.101MetThr: 2.101 ± 0.7
1.576MetVal: 1.576 ± 0.835
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.101AsnAla: 2.101 ± 0.7
1.05AsnCys: 1.05 ± 0.646
1.576AsnAsp: 1.576 ± 0.559
2.626AsnGlu: 2.626 ± 2.353
1.05AsnPhe: 1.05 ± 0.557
0.525AsnGly: 0.525 ± 0.278
2.101AsnHis: 2.101 ± 0.602
3.151AsnIle: 3.151 ± 1.67
2.101AsnLys: 2.101 ± 0.763
1.05AsnLeu: 1.05 ± 1.315
2.101AsnMet: 2.101 ± 0.7
1.576AsnAsn: 1.576 ± 0.703
3.676AsnPro: 3.676 ± 2.407
1.576AsnGln: 1.576 ± 0.835
2.101AsnArg: 2.101 ± 0.602
4.202AsnSer: 4.202 ± 1.453
1.05AsnThr: 1.05 ± 0.808
1.576AsnVal: 1.576 ± 0.835
0.525AsnTrp: 0.525 ± 0.278
2.626AsnTyr: 2.626 ± 0.491
0.0AsnXaa: 0.0 ± 0.0
Pro
2.101ProAla: 2.101 ± 0.763
0.525ProCys: 0.525 ± 0.278
2.626ProAsp: 2.626 ± 0.753
1.576ProGlu: 1.576 ± 0.703
3.151ProPhe: 3.151 ± 1.118
2.101ProGly: 2.101 ± 0.7
1.05ProHis: 1.05 ± 0.557
3.151ProIle: 3.151 ± 0.963
3.676ProLys: 3.676 ± 0.908
1.576ProLeu: 1.576 ± 0.559
1.05ProMet: 1.05 ± 0.557
2.626ProAsn: 2.626 ± 4.058
1.576ProPro: 1.576 ± 0.559
1.05ProGln: 1.05 ± 0.557
2.101ProArg: 2.101 ± 0.7
5.252ProSer: 5.252 ± 0.982
3.151ProThr: 3.151 ± 1.939
2.626ProVal: 2.626 ± 0.491
0.525ProTrp: 0.525 ± 0.983
0.525ProTyr: 0.525 ± 0.278
0.0ProXaa: 0.0 ± 0.0
Gln
2.101GlnAla: 2.101 ± 0.7
1.576GlnCys: 1.576 ± 0.835
2.101GlnAsp: 2.101 ± 1.113
2.101GlnGlu: 2.101 ± 0.602
1.05GlnPhe: 1.05 ± 0.557
1.576GlnGly: 1.576 ± 0.703
0.0GlnHis: 0.0 ± 0.0
2.101GlnIle: 2.101 ± 1.292
4.202GlnLys: 4.202 ± 2.585
2.101GlnLeu: 2.101 ± 2.756
0.0GlnMet: 0.0 ± 0.0
1.576GlnAsn: 1.576 ± 0.835
1.05GlnPro: 1.05 ± 0.808
0.0GlnGln: 0.0 ± 0.0
1.576GlnArg: 1.576 ± 0.835
3.676GlnSer: 3.676 ± 1.813
0.525GlnThr: 0.525 ± 0.278
1.05GlnVal: 1.05 ± 0.557
0.525GlnTrp: 0.525 ± 0.278
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.676ArgAla: 3.676 ± 1.948
3.151ArgCys: 3.151 ± 0.974
6.303ArgAsp: 6.303 ± 3.144
3.151ArgGlu: 3.151 ± 0.963
1.05ArgPhe: 1.05 ± 1.315
2.626ArgGly: 2.626 ± 1.488
0.0ArgHis: 0.0 ± 0.0
1.576ArgIle: 1.576 ± 0.703
4.202ArgLys: 4.202 ± 1.724
2.626ArgLeu: 2.626 ± 1.176
2.626ArgMet: 2.626 ± 0.753
1.05ArgAsn: 1.05 ± 0.557
2.101ArgPro: 2.101 ± 0.602
3.151ArgGln: 3.151 ± 0.963
2.101ArgArg: 2.101 ± 1.292
2.626ArgSer: 2.626 ± 1.176
3.676ArgThr: 3.676 ± 1.214
4.202ArgVal: 4.202 ± 1.717
0.525ArgTrp: 0.525 ± 0.823
2.626ArgTyr: 2.626 ± 1.391
0.0ArgXaa: 0.0 ± 0.0
Ser
5.777SerAla: 5.777 ± 2.582
5.252SerCys: 5.252 ± 1.978
2.626SerAsp: 2.626 ± 0.753
7.878SerGlu: 7.878 ± 2.403
4.727SerPhe: 4.727 ± 0.491
6.828SerGly: 6.828 ± 1.929
2.101SerHis: 2.101 ± 1.113
6.828SerIle: 6.828 ± 1.758
6.828SerLys: 6.828 ± 1.758
8.403SerLeu: 8.403 ± 1.349
0.525SerMet: 0.525 ± 0.983
4.202SerAsn: 4.202 ± 1.453
4.202SerPro: 4.202 ± 2.585
0.0SerGln: 0.0 ± 0.0
5.252SerArg: 5.252 ± 2.32
6.828SerSer: 6.828 ± 2.789
6.303SerThr: 6.303 ± 1.308
6.303SerVal: 6.303 ± 1.925
0.525SerTrp: 0.525 ± 0.278
1.576SerTyr: 1.576 ± 0.559
0.0SerXaa: 0.0 ± 0.0
Thr
3.151ThrAla: 3.151 ± 0.235
1.576ThrCys: 1.576 ± 0.835
2.626ThrAsp: 2.626 ± 0.753
4.202ThrGlu: 4.202 ± 1.453
3.151ThrPhe: 3.151 ± 0.235
6.828ThrGly: 6.828 ± 1.447
2.101ThrHis: 2.101 ± 1.113
6.303ThrIle: 6.303 ± 2.811
1.576ThrLys: 1.576 ± 0.703
6.303ThrLeu: 6.303 ± 0.47
1.576ThrMet: 1.576 ± 1.038
3.151ThrAsn: 3.151 ± 0.963
1.576ThrPro: 1.576 ± 0.835
1.576ThrGln: 1.576 ± 1.038
1.576ThrArg: 1.576 ± 1.038
5.777ThrSer: 5.777 ± 3.061
6.303ThrThr: 6.303 ± 1.582
4.727ThrVal: 4.727 ± 0.491
0.0ThrTrp: 0.0 ± 0.0
1.576ThrTyr: 1.576 ± 1.777
0.0ThrXaa: 0.0 ± 0.0
Val
2.626ValAla: 2.626 ± 1.176
0.525ValCys: 0.525 ± 0.278
2.626ValAsp: 2.626 ± 0.753
3.151ValGlu: 3.151 ± 0.963
2.101ValPhe: 2.101 ± 0.602
3.676ValGly: 3.676 ± 1.187
2.101ValHis: 2.101 ± 1.113
1.576ValIle: 1.576 ± 0.835
4.727ValLys: 4.727 ± 0.886
5.777ValLeu: 5.777 ± 1.761
1.05ValMet: 1.05 ± 0.559
3.151ValAsn: 3.151 ± 0.974
2.626ValPro: 2.626 ± 1.668
2.626ValGln: 2.626 ± 1.488
5.777ValArg: 5.777 ± 1.203
6.828ValSer: 6.828 ± 1.784
4.202ValThr: 4.202 ± 1.026
6.828ValVal: 6.828 ± 1.929
0.525ValTrp: 0.525 ± 0.278
2.101ValTyr: 2.101 ± 1.292
0.0ValXaa: 0.0 ± 0.0
Trp
0.525TrpAla: 0.525 ± 0.278
0.0TrpCys: 0.0 ± 0.0
0.525TrpAsp: 0.525 ± 0.278
1.05TrpGlu: 1.05 ± 0.557
0.0TrpPhe: 0.0 ± 0.0
0.525TrpGly: 0.525 ± 0.278
0.0TrpHis: 0.0 ± 0.0
0.525TrpIle: 0.525 ± 0.278
1.05TrpLys: 1.05 ± 0.808
1.576TrpLeu: 1.576 ± 0.835
0.0TrpMet: 0.0 ± 0.0
0.525TrpAsn: 0.525 ± 0.278
1.05TrpPro: 1.05 ± 1.646
0.525TrpGln: 0.525 ± 0.278
0.0TrpArg: 0.0 ± 0.0
0.525TrpSer: 0.525 ± 0.278
1.576TrpThr: 1.576 ± 1.038
1.05TrpVal: 1.05 ± 0.808
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.05TyrAla: 1.05 ± 0.646
0.525TyrCys: 0.525 ± 0.278
1.05TyrAsp: 1.05 ± 0.557
1.576TyrGlu: 1.576 ± 0.835
1.576TyrPhe: 1.576 ± 1.454
2.101TyrGly: 2.101 ± 1.113
1.576TyrHis: 1.576 ± 0.559
0.525TyrIle: 0.525 ± 0.278
3.151TyrLys: 3.151 ± 0.235
2.101TyrLeu: 2.101 ± 2.272
0.525TyrMet: 0.525 ± 0.278
0.525TyrAsn: 0.525 ± 0.823
2.626TyrPro: 2.626 ± 0.491
3.151TyrGln: 3.151 ± 2.076
1.576TyrArg: 1.576 ± 1.038
2.101TyrSer: 2.101 ± 1.113
1.576TyrThr: 1.576 ± 0.835
0.525TyrVal: 0.525 ± 0.278
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1905 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski