Amino acid dipepetide frequency for Aquimarina atlantica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.719AlaAla: 3.719 ± 0.057	0.517AlaCys: 0.517 ± 0.019	2.913AlaAsp: 2.913 ± 0.051	3.47AlaGlu: 3.47 ± 0.055	2.983AlaPhe: 2.983 ± 0.048	3.76AlaGly: 3.76 ± 0.065	1.031AlaHis: 1.031 ± 0.024	5.542AlaIle: 5.542 ± 0.062	4.526AlaLys: 4.526 ± 0.062	5.736AlaLeu: 5.736 ± 0.071	1.334AlaMet: 1.334 ± 0.028	3.309AlaAsn: 3.309 ± 0.055	1.742AlaPro: 1.742 ± 0.044	2.164AlaGln: 2.164 ± 0.04	1.816AlaArg: 1.816 ± 0.037	4.045AlaSer: 4.045 ± 0.06	3.608AlaThr: 3.608 ± 0.077	3.504AlaVal: 3.504 ± 0.05	0.555AlaTrp: 0.555 ± 0.021	2.473AlaTyr: 2.473 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.431CysAla: 0.431 ± 0.02	0.111CysCys: 0.111 ± 0.009	0.426CysAsp: 0.426 ± 0.018	0.443CysGlu: 0.443 ± 0.02	0.42CysPhe: 0.42 ± 0.018	0.571CysGly: 0.571 ± 0.021	0.17CysHis: 0.17 ± 0.01	0.721CysIle: 0.721 ± 0.023	0.526CysLys: 0.526 ± 0.018	0.618CysLeu: 0.618 ± 0.022	0.152CysMet: 0.152 ± 0.009	0.457CysAsn: 0.457 ± 0.019	0.313CysPro: 0.313 ± 0.022	0.209CysGln: 0.209 ± 0.01	0.202CysArg: 0.202 ± 0.01	0.622CysSer: 0.622 ± 0.021	0.493CysThr: 0.493 ± 0.03	0.41CysVal: 0.41 ± 0.018	0.073CysTrp: 0.073 ± 0.007	0.326CysTyr: 0.326 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.341AspAla: 3.341 ± 0.061	0.42AspCys: 0.42 ± 0.02	2.965AspAsp: 2.965 ± 0.051	3.367AspGlu: 3.367 ± 0.047	3.545AspPhe: 3.545 ± 0.049	3.521AspGly: 3.521 ± 0.075	1.136AspHis: 1.136 ± 0.026	5.036AspIle: 5.036 ± 0.06	4.11AspLys: 4.11 ± 0.064	5.019AspLeu: 5.019 ± 0.067	1.075AspMet: 1.075 ± 0.026	3.257AspAsn: 3.257 ± 0.055	1.963AspPro: 1.963 ± 0.045	2.022AspGln: 2.022 ± 0.043	1.888AspArg: 1.888 ± 0.035	3.246AspSer: 3.246 ± 0.053	3.177AspThr: 3.177 ± 0.05	3.33AspVal: 3.33 ± 0.051	0.756AspTrp: 0.756 ± 0.024	2.694AspTyr: 2.694 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	3.975GluAla: 3.975 ± 0.061	0.364GluCys: 0.364 ± 0.018	3.517GluAsp: 3.517 ± 0.051	5.242GluGlu: 5.242 ± 0.098	2.868GluPhe: 2.868 ± 0.048	3.638GluGly: 3.638 ± 0.048	1.154GluHis: 1.154 ± 0.029	5.848GluIle: 5.848 ± 0.064	6.058GluLys: 6.058 ± 0.078	6.187GluLeu: 6.187 ± 0.093	1.415GluMet: 1.415 ± 0.033	4.527GluAsn: 4.527 ± 0.054	1.487GluPro: 1.487 ± 0.031	2.289GluGln: 2.289 ± 0.041	2.362GluArg: 2.362 ± 0.049	3.381GluSer: 3.381 ± 0.047	3.518GluThr: 3.518 ± 0.052	4.106GluVal: 4.106 ± 0.05	0.59GluTrp: 0.59 ± 0.019	2.735GluTyr: 2.735 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.746PheAla: 2.746 ± 0.053	0.441PheCys: 0.441 ± 0.017	3.271PheAsp: 3.271 ± 0.052	3.317PheGlu: 3.317 ± 0.047	2.844PhePhe: 2.844 ± 0.053	3.393PheGly: 3.393 ± 0.055	0.812PheHis: 0.812 ± 0.024	4.118PheIle: 4.118 ± 0.059	3.713PheLys: 3.713 ± 0.057	4.798PheLeu: 4.798 ± 0.068	1.099PheMet: 1.099 ± 0.025	3.152PheAsn: 3.152 ± 0.046	1.668PhePro: 1.668 ± 0.034	1.404PheGln: 1.404 ± 0.03	1.683PheArg: 1.683 ± 0.034	4.104PheSer: 4.104 ± 0.058	3.132PheThr: 3.132 ± 0.052	2.9PheVal: 2.9 ± 0.051	0.615PheTrp: 0.615 ± 0.02	2.332PheTyr: 2.332 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	3.9GlyAla: 3.9 ± 0.064	0.587GlyCys: 0.587 ± 0.023	3.342GlyAsp: 3.342 ± 0.059	3.539GlyGlu: 3.539 ± 0.049	3.607GlyPhe: 3.607 ± 0.059	4.421GlyGly: 4.421 ± 0.086	1.046GlyHis: 1.046 ± 0.027	5.531GlyIle: 5.531 ± 0.057	4.754GlyLys: 4.754 ± 0.058	5.394GlyLeu: 5.394 ± 0.06	1.455GlyMet: 1.455 ± 0.03	3.844GlyAsn: 3.844 ± 0.065	1.321GlyPro: 1.321 ± 0.036	1.732GlyGln: 1.732 ± 0.033	1.968GlyArg: 1.968 ± 0.037	3.974GlySer: 3.974 ± 0.068	3.946GlyThr: 3.946 ± 0.078	4.419GlyVal: 4.419 ± 0.058	0.782GlyTrp: 0.782 ± 0.023	3.093GlyTyr: 3.093 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	0.858HisAla: 0.858 ± 0.023	0.194HisCys: 0.194 ± 0.011	0.831HisAsp: 0.831 ± 0.025	0.937HisGlu: 0.937 ± 0.026	1.114HisPhe: 1.114 ± 0.031	1.03HisGly: 1.03 ± 0.028	0.525HisHis: 0.525 ± 0.018	1.665HisIle: 1.665 ± 0.037	1.397HisLys: 1.397 ± 0.032	1.76HisLeu: 1.76 ± 0.035	0.359HisMet: 0.359 ± 0.015	1.076HisAsn: 1.076 ± 0.026	0.859HisPro: 0.859 ± 0.027	0.799HisGln: 0.799 ± 0.02	0.696HisArg: 0.696 ± 0.024	1.091HisSer: 1.091 ± 0.028	1.106HisThr: 1.106 ± 0.027	0.868HisVal: 0.868 ± 0.025	0.216HisTrp: 0.216 ± 0.013	0.901HisTyr: 0.901 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.738IleAla: 5.738 ± 0.063	0.653IleCys: 0.653 ± 0.022	5.312IleAsp: 5.312 ± 0.056	6.085IleGlu: 6.085 ± 0.07	3.733IlePhe: 3.733 ± 0.055	5.429IleGly: 5.429 ± 0.073	1.595IleHis: 1.595 ± 0.03	6.677IleIle: 6.677 ± 0.093	6.463IleLys: 6.463 ± 0.076	7.642IleLeu: 7.642 ± 0.099	1.374IleMet: 1.374 ± 0.029	5.067IleAsn: 5.067 ± 0.055	3.409IlePro: 3.409 ± 0.051	2.768IleGln: 2.768 ± 0.042	2.805IleArg: 2.805 ± 0.043	6.226IleSer: 6.226 ± 0.076	5.616IleThr: 5.616 ± 0.075	4.978IleVal: 4.978 ± 0.061	0.759IleTrp: 0.759 ± 0.021	3.0IleTyr: 3.0 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.742LysAla: 4.742 ± 0.067	0.345LysCys: 0.345 ± 0.016	4.493LysAsp: 4.493 ± 0.063	6.856LysGlu: 6.856 ± 0.085	2.771LysPhe: 2.771 ± 0.046	4.514LysGly: 4.514 ± 0.058	1.46LysHis: 1.46 ± 0.032	6.783LysIle: 6.783 ± 0.088	7.582LysLys: 7.582 ± 0.103	6.613LysLeu: 6.613 ± 0.075	1.855LysMet: 1.855 ± 0.038	5.701LysAsn: 5.701 ± 0.084	2.291LysPro: 2.291 ± 0.039	2.744LysGln: 2.744 ± 0.051	3.003LysArg: 3.003 ± 0.049	4.698LysSer: 4.698 ± 0.06	4.85LysThr: 4.85 ± 0.062	4.523LysVal: 4.523 ± 0.058	0.8LysTrp: 0.8 ± 0.022	3.131LysTyr: 3.131 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	5.162LeuAla: 5.162 ± 0.059	0.722LeuCys: 0.722 ± 0.026	5.134LeuAsp: 5.134 ± 0.059	5.914LeuGlu: 5.914 ± 0.075	5.027LeuPhe: 5.027 ± 0.071	5.698LeuGly: 5.698 ± 0.069	1.659LeuHis: 1.659 ± 0.038	7.383LeuIle: 7.383 ± 0.088	7.549LeuLys: 7.549 ± 0.095	8.652LeuLeu: 8.652 ± 0.102	1.843LeuMet: 1.843 ± 0.038	5.234LeuAsn: 5.234 ± 0.069	3.442LeuPro: 3.442 ± 0.05	3.365LeuGln: 3.365 ± 0.058	3.083LeuArg: 3.083 ± 0.051	7.004LeuSer: 7.004 ± 0.091	5.077LeuThr: 5.077 ± 0.061	5.167LeuVal: 5.167 ± 0.06	0.881LeuTrp: 0.881 ± 0.022	3.425LeuTyr: 3.425 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.337MetAla: 1.337 ± 0.029	0.144MetCys: 0.144 ± 0.01	1.039MetAsp: 1.039 ± 0.029	1.07MetGlu: 1.07 ± 0.028	0.816MetPhe: 0.816 ± 0.023	1.255MetGly: 1.255 ± 0.028	0.394MetHis: 0.394 ± 0.016	1.728MetIle: 1.728 ± 0.031	2.106MetLys: 2.106 ± 0.036	1.748MetLeu: 1.748 ± 0.035	0.508MetMet: 0.508 ± 0.018	1.331MetAsn: 1.331 ± 0.028	0.705MetPro: 0.705 ± 0.021	0.743MetGln: 0.743 ± 0.022	0.8MetArg: 0.8 ± 0.026	1.304MetSer: 1.304 ± 0.029	1.049MetThr: 1.049 ± 0.024	1.264MetVal: 1.264 ± 0.029	0.148MetTrp: 0.148 ± 0.01	0.758MetTyr: 0.758 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.647AsnAla: 3.647 ± 0.059	0.497AsnCys: 0.497 ± 0.024	3.42AsnAsp: 3.42 ± 0.048	3.646AsnGlu: 3.646 ± 0.049	2.973AsnPhe: 2.973 ± 0.051	4.062AsnGly: 4.062 ± 0.063	1.125AsnHis: 1.125 ± 0.03	5.079AsnIle: 5.079 ± 0.056	4.436AsnLys: 4.436 ± 0.066	5.234AsnLeu: 5.234 ± 0.064	1.202AsnMet: 1.202 ± 0.031	3.89AsnAsn: 3.89 ± 0.065	2.632AsnPro: 2.632 ± 0.048	2.349AsnGln: 2.349 ± 0.042	2.284AsnArg: 2.284 ± 0.042	3.961AsnSer: 3.961 ± 0.055	4.403AsnThr: 4.403 ± 0.06	3.432AsnVal: 3.432 ± 0.056	0.764AsnTrp: 0.764 ± 0.023	2.74AsnTyr: 2.74 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	1.752ProAla: 1.752 ± 0.049	0.228ProCys: 0.228 ± 0.013	2.18ProAsp: 2.18 ± 0.039	2.683ProGlu: 2.683 ± 0.041	1.82ProPhe: 1.82 ± 0.039	2.022ProGly: 2.022 ± 0.045	0.591ProHis: 0.591 ± 0.02	2.757ProIle: 2.757 ± 0.046	2.673ProLys: 2.673 ± 0.045	2.829ProLeu: 2.829 ± 0.05	0.61ProMet: 0.61 ± 0.018	2.202ProAsn: 2.202 ± 0.044	0.854ProPro: 0.854 ± 0.032	1.064ProGln: 1.064 ± 0.024	0.884ProArg: 0.884 ± 0.023	2.093ProSer: 2.093 ± 0.037	1.898ProThr: 1.898 ± 0.048	2.293ProVal: 2.293 ± 0.053	0.34ProTrp: 0.34 ± 0.015	1.367ProTyr: 1.367 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	1.805GlnAla: 1.805 ± 0.04	0.203GlnCys: 0.203 ± 0.012	1.681GlnAsp: 1.681 ± 0.034	2.537GlnGlu: 2.537 ± 0.048	1.623GlnPhe: 1.623 ± 0.034	1.874GlnGly: 1.874 ± 0.036	0.643GlnHis: 0.643 ± 0.018	2.722GlnIle: 2.722 ± 0.038	3.123GlnLys: 3.123 ± 0.054	3.445GlnLeu: 3.445 ± 0.053	0.705GlnMet: 0.705 ± 0.021	2.307GlnAsn: 2.307 ± 0.042	1.1GlnPro: 1.1 ± 0.029	1.502GlnGln: 1.502 ± 0.033	1.254GlnArg: 1.254 ± 0.029	1.983GlnSer: 1.983 ± 0.044	1.812GlnThr: 1.812 ± 0.039	1.896GlnVal: 1.896 ± 0.038	0.396GlnTrp: 0.396 ± 0.016	1.492GlnTyr: 1.492 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	1.857ArgAla: 1.857 ± 0.04	0.206ArgCys: 0.206 ± 0.013	1.785ArgAsp: 1.785 ± 0.032	2.116ArgGlu: 2.116 ± 0.039	1.924ArgPhe: 1.924 ± 0.035	1.875ArgGly: 1.875 ± 0.038	0.6ArgHis: 0.6 ± 0.017	3.132ArgIle: 3.132 ± 0.051	2.942ArgLys: 2.942 ± 0.049	3.278ArgLeu: 3.278 ± 0.051	0.823ArgMet: 0.823 ± 0.025	2.109ArgAsn: 2.109 ± 0.035	1.025ArgPro: 1.025 ± 0.022	1.058ArgGln: 1.058 ± 0.028	1.246ArgArg: 1.246 ± 0.035	2.009ArgSer: 2.009 ± 0.037	1.855ArgThr: 1.855 ± 0.035	2.016ArgVal: 2.016 ± 0.035	0.395ArgTrp: 0.395 ± 0.017	1.737ArgTyr: 1.737 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.439SerAla: 3.439 ± 0.055	0.742SerCys: 0.742 ± 0.024	3.705SerAsp: 3.705 ± 0.053	4.01SerGlu: 4.01 ± 0.059	4.045SerPhe: 4.045 ± 0.051	4.744SerGly: 4.744 ± 0.078	1.105SerHis: 1.105 ± 0.031	5.903SerIle: 5.903 ± 0.077	5.242SerLys: 5.242 ± 0.066	6.085SerLeu: 6.085 ± 0.073	1.241SerMet: 1.241 ± 0.029	3.973SerAsn: 3.973 ± 0.053	2.034SerPro: 2.034 ± 0.038	2.086SerGln: 2.086 ± 0.036	2.122SerArg: 2.122 ± 0.041	4.652SerSer: 4.652 ± 0.064	3.796SerThr: 3.796 ± 0.056	3.775SerVal: 3.775 ± 0.048	0.793SerTrp: 0.793 ± 0.026	3.068SerTyr: 3.068 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	3.627ThrAla: 3.627 ± 0.066	0.382ThrCys: 0.382 ± 0.022	3.292ThrAsp: 3.292 ± 0.061	3.264ThrGlu: 3.264 ± 0.044	3.004ThrPhe: 3.004 ± 0.047	4.034ThrGly: 4.034 ± 0.08	1.096ThrHis: 1.096 ± 0.027	5.76ThrIle: 5.76 ± 0.078	4.222ThrLys: 4.222 ± 0.054	5.6ThrLeu: 5.6 ± 0.072	0.966ThrMet: 0.966 ± 0.027	3.558ThrAsn: 3.558 ± 0.051	2.589ThrPro: 2.589 ± 0.06	1.986ThrGln: 1.986 ± 0.033	1.773ThrArg: 1.773 ± 0.034	4.236ThrSer: 4.236 ± 0.058	4.132ThrThr: 4.132 ± 0.083	3.82ThrVal: 3.82 ± 0.091	0.596ThrTrp: 0.596 ± 0.025	2.664ThrTyr: 2.664 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	3.677ValAla: 3.677 ± 0.059	0.474ValCys: 0.474 ± 0.018	3.414ValAsp: 3.414 ± 0.051	3.622ValGlu: 3.622 ± 0.049	3.405ValPhe: 3.405 ± 0.054	3.509ValGly: 3.509 ± 0.058	1.005ValHis: 1.005 ± 0.025	4.967ValIle: 4.967 ± 0.061	4.156ValLys: 4.156 ± 0.054	5.939ValLeu: 5.939 ± 0.076	1.218ValMet: 1.218 ± 0.029	3.415ValAsn: 3.415 ± 0.055	1.998ValPro: 1.998 ± 0.043	1.775ValGln: 1.775 ± 0.036	1.872ValArg: 1.872 ± 0.037	4.403ValSer: 4.403 ± 0.06	3.783ValThr: 3.783 ± 0.095	3.922ValVal: 3.922 ± 0.062	0.597ValTrp: 0.597 ± 0.022	2.396ValTyr: 2.396 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.568TrpAla: 0.568 ± 0.02	0.102TrpCys: 0.102 ± 0.008	0.64TrpAsp: 0.64 ± 0.02	0.691TrpGlu: 0.691 ± 0.022	0.543TrpPhe: 0.543 ± 0.021	0.698TrpGly: 0.698 ± 0.024	0.202TrpHis: 0.202 ± 0.01	0.849TrpIle: 0.849 ± 0.026	0.884TrpLys: 0.884 ± 0.025	0.957TrpLeu: 0.957 ± 0.027	0.287TrpMet: 0.287 ± 0.013	0.709TrpAsn: 0.709 ± 0.021	0.223TrpPro: 0.223 ± 0.013	0.401TrpGln: 0.401 ± 0.016	0.402TrpArg: 0.402 ± 0.017	0.701TrpSer: 0.701 ± 0.021	0.547TrpThr: 0.547 ± 0.026	0.649TrpVal: 0.649 ± 0.023	0.149TrpTrp: 0.149 ± 0.01	0.482TrpTyr: 0.482 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.426TyrAla: 2.426 ± 0.039	0.365TyrCys: 0.365 ± 0.016	2.503TyrAsp: 2.503 ± 0.04	2.455TyrGlu: 2.455 ± 0.04	2.478TyrPhe: 2.478 ± 0.041	2.609TyrGly: 2.609 ± 0.045	0.934TyrHis: 0.934 ± 0.022	3.127TyrIle: 3.127 ± 0.045	3.294TyrLys: 3.294 ± 0.056	3.886TyrLeu: 3.886 ± 0.054	0.723TyrMet: 0.723 ± 0.02	2.656TyrAsn: 2.656 ± 0.043	1.488TyrPro: 1.488 ± 0.033	1.645TyrGln: 1.645 ± 0.035	1.843TyrArg: 1.843 ± 0.036	2.825TyrSer: 2.825 ± 0.044	2.803TyrThr: 2.803 ± 0.056	2.275TyrVal: 2.275 ± 0.04	0.48TyrTrp: 0.48 ± 0.017	1.992TyrTyr: 1.992 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4786 proteins (1642244 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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