Amino acid dipepetide frequency for Duck adenovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.465AlaAla: 4.465 ± 0.983
1.135AlaCys: 1.135 ± 0.294
3.405AlaAsp: 3.405 ± 0.582
3.481AlaGlu: 3.481 ± 0.748
2.951AlaPhe: 2.951 ± 0.541
3.178AlaGly: 3.178 ± 0.435
1.589AlaHis: 1.589 ± 0.348
3.784AlaIle: 3.784 ± 0.635
3.405AlaLys: 3.405 ± 0.63
5.373AlaLeu: 5.373 ± 0.677
2.194AlaMet: 2.194 ± 0.509
2.724AlaAsn: 2.724 ± 0.425
3.33AlaPro: 3.33 ± 0.561
2.346AlaGln: 2.346 ± 0.4
2.724AlaArg: 2.724 ± 0.449
3.784AlaSer: 3.784 ± 0.314
3.708AlaThr: 3.708 ± 0.463
4.843AlaVal: 4.843 ± 0.83
0.454AlaTrp: 0.454 ± 0.151
2.27AlaTyr: 2.27 ± 0.407
0.0AlaXaa: 0.0 ± 0.0
Cys
0.681CysAla: 0.681 ± 0.217
0.151CysCys: 0.151 ± 0.097
0.984CysAsp: 0.984 ± 0.305
0.832CysGlu: 0.832 ± 0.246
0.605CysPhe: 0.605 ± 0.215
1.438CysGly: 1.438 ± 0.396
0.53CysHis: 0.53 ± 0.192
1.059CysIle: 1.059 ± 0.311
0.908CysLys: 0.908 ± 0.235
1.059CysLeu: 1.059 ± 0.317
0.53CysMet: 0.53 ± 0.173
1.362CysAsn: 1.362 ± 0.354
1.135CysPro: 1.135 ± 0.252
0.605CysGln: 0.605 ± 0.177
0.908CysArg: 0.908 ± 0.294
1.816CysSer: 1.816 ± 0.448
1.665CysThr: 1.665 ± 0.352
1.211CysVal: 1.211 ± 0.258
0.378CysTrp: 0.378 ± 0.179
1.211CysTyr: 1.211 ± 0.295
0.0CysXaa: 0.0 ± 0.0
Asp
2.8AspAla: 2.8 ± 0.407
1.135AspCys: 1.135 ± 0.406
3.632AspAsp: 3.632 ± 0.54
4.692AspGlu: 4.692 ± 0.697
2.8AspPhe: 2.8 ± 0.47
2.951AspGly: 2.951 ± 0.628
1.362AspHis: 1.362 ± 0.328
3.784AspIle: 3.784 ± 0.471
1.589AspLys: 1.589 ± 0.302
4.767AspLeu: 4.767 ± 0.595
1.589AspMet: 1.589 ± 0.319
2.951AspAsn: 2.951 ± 0.567
4.616AspPro: 4.616 ± 0.841
1.74AspGln: 1.74 ± 0.351
2.876AspArg: 2.876 ± 0.405
4.313AspSer: 4.313 ± 0.581
2.724AspThr: 2.724 ± 0.695
2.951AspVal: 2.951 ± 0.443
0.832AspTrp: 0.832 ± 0.293
2.497AspTyr: 2.497 ± 0.429
0.0AspXaa: 0.0 ± 0.0
Glu
2.951GluAla: 2.951 ± 0.793
0.984GluCys: 0.984 ± 0.282
4.086GluAsp: 4.086 ± 0.692
6.356GluGlu: 6.356 ± 1.521
1.816GluPhe: 1.816 ± 0.408
3.33GluGly: 3.33 ± 0.726
0.984GluHis: 0.984 ± 0.383
3.027GluIle: 3.027 ± 0.41
3.103GluLys: 3.103 ± 0.555
4.843GluLeu: 4.843 ± 0.647
1.513GluMet: 1.513 ± 0.355
2.8GluAsn: 2.8 ± 0.399
1.892GluPro: 1.892 ± 0.423
1.74GluGln: 1.74 ± 0.439
2.724GluArg: 2.724 ± 0.473
4.692GluSer: 4.692 ± 0.677
2.573GluThr: 2.573 ± 0.487
3.708GluVal: 3.708 ± 0.639
0.681GluTrp: 0.681 ± 0.283
1.816GluTyr: 1.816 ± 0.372
0.0GluXaa: 0.0 ± 0.0
Phe
2.27PheAla: 2.27 ± 0.372
0.681PheCys: 0.681 ± 0.216
2.724PheAsp: 2.724 ± 0.507
2.573PheGlu: 2.573 ± 0.389
2.043PhePhe: 2.043 ± 0.39
2.119PheGly: 2.119 ± 0.303
1.438PheHis: 1.438 ± 0.346
2.724PheIle: 2.724 ± 0.388
3.103PheLys: 3.103 ± 0.504
4.086PheLeu: 4.086 ± 0.751
1.438PheMet: 1.438 ± 0.328
2.421PheAsn: 2.421 ± 0.34
1.513PhePro: 1.513 ± 0.379
0.832PheGln: 0.832 ± 0.184
2.573PheArg: 2.573 ± 0.32
3.481PheSer: 3.481 ± 0.579
2.876PheThr: 2.876 ± 0.442
2.497PheVal: 2.497 ± 0.315
0.454PheTrp: 0.454 ± 0.193
2.194PheTyr: 2.194 ± 0.369
0.0PheXaa: 0.0 ± 0.0
Gly
4.162GlyAla: 4.162 ± 0.592
0.908GlyCys: 0.908 ± 0.31
3.103GlyAsp: 3.103 ± 0.296
2.346GlyGlu: 2.346 ± 0.341
2.649GlyPhe: 2.649 ± 0.411
4.767GlyGly: 4.767 ± 0.479
1.362GlyHis: 1.362 ± 0.273
3.33GlyIle: 3.33 ± 0.612
2.951GlyLys: 2.951 ± 0.456
4.389GlyLeu: 4.389 ± 1.017
1.286GlyMet: 1.286 ± 0.226
3.178GlyAsn: 3.178 ± 0.563
2.951GlyPro: 2.951 ± 0.472
0.908GlyGln: 0.908 ± 0.269
3.935GlyArg: 3.935 ± 0.657
4.767GlySer: 4.767 ± 0.724
2.951GlyThr: 2.951 ± 0.512
4.465GlyVal: 4.465 ± 0.568
1.286GlyTrp: 1.286 ± 0.283
1.816GlyTyr: 1.816 ± 0.29
0.0GlyXaa: 0.0 ± 0.0
His
1.665HisAla: 1.665 ± 0.251
0.378HisCys: 0.378 ± 0.152
1.362HisAsp: 1.362 ± 0.316
1.211HisGlu: 1.211 ± 0.267
0.53HisPhe: 0.53 ± 0.217
1.438HisGly: 1.438 ± 0.276
0.984HisHis: 0.984 ± 0.264
1.362HisIle: 1.362 ± 0.355
1.135HisLys: 1.135 ± 0.26
2.346HisLeu: 2.346 ± 0.431
0.303HisMet: 0.303 ± 0.151
1.362HisAsn: 1.362 ± 0.246
1.816HisPro: 1.816 ± 0.445
0.832HisGln: 0.832 ± 0.269
1.589HisArg: 1.589 ± 0.293
2.27HisSer: 2.27 ± 0.38
1.135HisThr: 1.135 ± 0.327
1.892HisVal: 1.892 ± 0.366
0.378HisTrp: 0.378 ± 0.202
0.681HisTyr: 0.681 ± 0.205
0.0HisXaa: 0.0 ± 0.0
Ile
2.951IleAla: 2.951 ± 0.57
1.438IleCys: 1.438 ± 0.413
3.481IleAsp: 3.481 ± 0.571
2.724IleGlu: 2.724 ± 0.435
2.421IlePhe: 2.421 ± 0.458
3.784IleGly: 3.784 ± 0.546
1.438IleHis: 1.438 ± 0.376
3.103IleIle: 3.103 ± 0.62
3.027IleLys: 3.027 ± 0.451
4.086IleLeu: 4.086 ± 0.592
1.362IleMet: 1.362 ± 0.286
3.557IleAsn: 3.557 ± 0.603
4.465IlePro: 4.465 ± 0.618
2.421IleGln: 2.421 ± 0.379
3.103IleArg: 3.103 ± 0.41
4.011IleSer: 4.011 ± 0.49
2.573IleThr: 2.573 ± 0.392
3.632IleVal: 3.632 ± 0.664
0.378IleTrp: 0.378 ± 0.15
2.119IleTyr: 2.119 ± 0.386
0.0IleXaa: 0.0 ± 0.0
Lys
3.254LysAla: 3.254 ± 0.617
1.286LysCys: 1.286 ± 0.324
2.649LysAsp: 2.649 ± 0.591
2.649LysGlu: 2.649 ± 0.622
2.724LysPhe: 2.724 ± 0.3
2.119LysGly: 2.119 ± 0.301
1.059LysHis: 1.059 ± 0.292
2.043LysIle: 2.043 ± 0.401
2.27LysLys: 2.27 ± 0.664
5.221LysLeu: 5.221 ± 0.79
1.74LysMet: 1.74 ± 0.325
2.27LysAsn: 2.27 ± 0.429
2.194LysPro: 2.194 ± 0.523
2.119LysGln: 2.119 ± 0.521
3.708LysArg: 3.708 ± 0.658
2.649LysSer: 2.649 ± 0.415
2.724LysThr: 2.724 ± 0.454
3.103LysVal: 3.103 ± 0.497
0.681LysTrp: 0.681 ± 0.203
2.724LysTyr: 2.724 ± 0.549
0.0LysXaa: 0.0 ± 0.0
Leu
4.919LeuAla: 4.919 ± 0.536
2.043LeuCys: 2.043 ± 0.403
3.935LeuAsp: 3.935 ± 0.586
4.011LeuGlu: 4.011 ± 0.657
3.557LeuPhe: 3.557 ± 0.523
4.011LeuGly: 4.011 ± 0.493
2.573LeuHis: 2.573 ± 0.555
4.994LeuIle: 4.994 ± 0.516
4.692LeuLys: 4.692 ± 0.567
6.356LeuLeu: 6.356 ± 0.861
2.876LeuMet: 2.876 ± 0.55
4.086LeuAsn: 4.086 ± 0.667
4.238LeuPro: 4.238 ± 0.528
3.178LeuGln: 3.178 ± 0.492
4.313LeuArg: 4.313 ± 0.731
5.221LeuSer: 5.221 ± 0.647
5.751LeuThr: 5.751 ± 0.789
5.146LeuVal: 5.146 ± 0.544
1.438LeuTrp: 1.438 ± 0.343
3.405LeuTyr: 3.405 ± 0.602
0.0LeuXaa: 0.0 ± 0.0
Met
2.876MetAla: 2.876 ± 0.426
0.53MetCys: 0.53 ± 0.205
2.346MetAsp: 2.346 ± 0.46
1.135MetGlu: 1.135 ± 0.315
0.984MetPhe: 0.984 ± 0.272
1.286MetGly: 1.286 ± 0.423
0.757MetHis: 0.757 ± 0.323
1.513MetIle: 1.513 ± 0.402
1.362MetLys: 1.362 ± 0.346
1.892MetLeu: 1.892 ± 0.391
1.286MetMet: 1.286 ± 0.376
2.194MetAsn: 2.194 ± 0.367
1.135MetPro: 1.135 ± 0.274
1.135MetGln: 1.135 ± 0.347
1.589MetArg: 1.589 ± 0.382
3.254MetSer: 3.254 ± 0.52
1.589MetThr: 1.589 ± 0.33
1.892MetVal: 1.892 ± 0.36
0.454MetTrp: 0.454 ± 0.191
1.362MetTyr: 1.362 ± 0.277
0.0MetXaa: 0.0 ± 0.0
Asn
2.497AsnAla: 2.497 ± 0.373
0.681AsnCys: 0.681 ± 0.228
2.876AsnAsp: 2.876 ± 0.494
3.103AsnGlu: 3.103 ± 0.455
2.27AsnPhe: 2.27 ± 0.54
4.011AsnGly: 4.011 ± 0.977
1.513AsnHis: 1.513 ± 0.273
2.951AsnIle: 2.951 ± 0.633
1.816AsnLys: 1.816 ± 0.392
4.313AsnLeu: 4.313 ± 0.586
2.8AsnMet: 2.8 ± 0.564
2.724AsnAsn: 2.724 ± 0.574
3.405AsnPro: 3.405 ± 0.544
1.665AsnGln: 1.665 ± 0.35
2.27AsnArg: 2.27 ± 0.472
4.313AsnSer: 4.313 ± 0.697
3.103AsnThr: 3.103 ± 0.643
3.103AsnVal: 3.103 ± 0.546
0.681AsnTrp: 0.681 ± 0.225
2.649AsnTyr: 2.649 ± 0.426
0.0AsnXaa: 0.0 ± 0.0
Pro
4.238ProAla: 4.238 ± 0.571
0.53ProCys: 0.53 ± 0.218
3.027ProAsp: 3.027 ± 0.449
2.573ProGlu: 2.573 ± 0.564
3.027ProPhe: 3.027 ± 0.59
2.119ProGly: 2.119 ± 0.363
1.74ProHis: 1.74 ± 0.314
3.405ProIle: 3.405 ± 0.673
2.951ProLys: 2.951 ± 0.663
4.616ProLeu: 4.616 ± 0.815
1.589ProMet: 1.589 ± 0.373
2.497ProAsn: 2.497 ± 0.509
7.037ProPro: 7.037 ± 2.094
2.573ProGln: 2.573 ± 0.466
3.481ProArg: 3.481 ± 0.563
4.994ProSer: 4.994 ± 0.451
3.784ProThr: 3.784 ± 0.58
3.254ProVal: 3.254 ± 0.391
0.076ProTrp: 0.076 ± 0.069
2.346ProTyr: 2.346 ± 0.409
0.0ProXaa: 0.0 ± 0.0
Gln
1.892GlnAla: 1.892 ± 0.401
0.757GlnCys: 0.757 ± 0.234
1.816GlnAsp: 1.816 ± 0.309
1.513GlnGlu: 1.513 ± 0.369
1.513GlnPhe: 1.513 ± 0.336
1.135GlnGly: 1.135 ± 0.32
0.605GlnHis: 0.605 ± 0.188
1.665GlnIle: 1.665 ± 0.375
1.967GlnLys: 1.967 ± 0.46
4.162GlnLeu: 4.162 ± 0.696
1.135GlnMet: 1.135 ± 0.34
2.043GlnAsn: 2.043 ± 0.405
1.967GlnPro: 1.967 ± 0.372
1.589GlnGln: 1.589 ± 0.373
1.665GlnArg: 1.665 ± 0.482
2.876GlnSer: 2.876 ± 0.422
1.513GlnThr: 1.513 ± 0.428
1.665GlnVal: 1.665 ± 0.283
0.378GlnTrp: 0.378 ± 0.148
1.665GlnTyr: 1.665 ± 0.387
0.0GlnXaa: 0.0 ± 0.0
Arg
3.481ArgAla: 3.481 ± 0.622
1.059ArgCys: 1.059 ± 0.273
2.649ArgAsp: 2.649 ± 0.497
3.103ArgGlu: 3.103 ± 0.558
2.27ArgPhe: 2.27 ± 0.36
3.935ArgGly: 3.935 ± 0.686
1.74ArgHis: 1.74 ± 0.406
2.573ArgIle: 2.573 ± 0.564
2.497ArgLys: 2.497 ± 0.478
4.616ArgLeu: 4.616 ± 0.698
1.513ArgMet: 1.513 ± 0.324
2.573ArgAsn: 2.573 ± 0.634
2.649ArgPro: 2.649 ± 0.582
2.043ArgGln: 2.043 ± 0.471
5.07ArgArg: 5.07 ± 1.399
4.238ArgSer: 4.238 ± 0.716
2.497ArgThr: 2.497 ± 0.513
3.708ArgVal: 3.708 ± 0.717
0.832ArgTrp: 0.832 ± 0.218
2.194ArgTyr: 2.194 ± 0.375
0.0ArgXaa: 0.0 ± 0.0
Ser
5.07SerAla: 5.07 ± 0.678
2.043SerCys: 2.043 ± 0.479
4.994SerAsp: 4.994 ± 0.534
4.692SerGlu: 4.692 ± 0.538
2.724SerPhe: 2.724 ± 0.504
5.978SerGly: 5.978 ± 0.764
1.438SerHis: 1.438 ± 0.323
5.448SerIle: 5.448 ± 0.746
3.254SerLys: 3.254 ± 0.688
5.07SerLeu: 5.07 ± 0.748
1.74SerMet: 1.74 ± 0.425
3.784SerAsn: 3.784 ± 0.641
4.238SerPro: 4.238 ± 0.52
2.043SerGln: 2.043 ± 0.4
4.389SerArg: 4.389 ± 0.697
8.021SerSer: 8.021 ± 1.189
4.54SerThr: 4.54 ± 0.629
7.189SerVal: 7.189 ± 1.23
0.984SerTrp: 0.984 ± 0.288
2.951SerTyr: 2.951 ± 0.546
0.0SerXaa: 0.0 ± 0.0
Thr
3.859ThrAla: 3.859 ± 0.428
0.984ThrCys: 0.984 ± 0.227
2.8ThrAsp: 2.8 ± 0.312
3.33ThrGlu: 3.33 ± 0.539
2.27ThrPhe: 2.27 ± 0.283
3.103ThrGly: 3.103 ± 0.585
0.832ThrHis: 0.832 ± 0.234
3.178ThrIle: 3.178 ± 0.521
2.649ThrLys: 2.649 ± 0.417
4.389ThrLeu: 4.389 ± 0.924
1.211ThrMet: 1.211 ± 0.244
3.859ThrAsn: 3.859 ± 0.534
3.859ThrPro: 3.859 ± 0.619
1.967ThrGln: 1.967 ± 0.312
3.254ThrArg: 3.254 ± 0.428
4.389ThrSer: 4.389 ± 0.575
6.432ThrThr: 6.432 ± 2.666
4.465ThrVal: 4.465 ± 0.573
0.605ThrTrp: 0.605 ± 0.203
2.649ThrTyr: 2.649 ± 0.439
0.0ThrXaa: 0.0 ± 0.0
Val
3.027ValAla: 3.027 ± 0.477
1.513ValCys: 1.513 ± 0.407
3.784ValAsp: 3.784 ± 0.537
2.573ValGlu: 2.573 ± 0.481
3.784ValPhe: 3.784 ± 0.509
3.859ValGly: 3.859 ± 0.509
1.665ValHis: 1.665 ± 0.358
3.178ValIle: 3.178 ± 0.59
4.162ValLys: 4.162 ± 0.5
5.448ValLeu: 5.448 ± 0.544
1.74ValMet: 1.74 ± 0.251
3.632ValAsn: 3.632 ± 0.38
4.389ValPro: 4.389 ± 0.591
2.194ValGln: 2.194 ± 0.473
2.421ValArg: 2.421 ± 0.386
6.508ValSer: 6.508 ± 1.085
4.994ValThr: 4.994 ± 0.603
5.373ValVal: 5.373 ± 0.691
0.832ValTrp: 0.832 ± 0.236
2.724ValTyr: 2.724 ± 0.48
0.0ValXaa: 0.0 ± 0.0
Trp
0.908TrpAla: 0.908 ± 0.247
0.303TrpCys: 0.303 ± 0.147
0.454TrpAsp: 0.454 ± 0.182
0.605TrpGlu: 0.605 ± 0.212
0.53TrpPhe: 0.53 ± 0.185
0.681TrpGly: 0.681 ± 0.255
0.227TrpHis: 0.227 ± 0.135
0.53TrpIle: 0.53 ± 0.27
0.53TrpLys: 0.53 ± 0.239
0.832TrpLeu: 0.832 ± 0.242
0.681TrpMet: 0.681 ± 0.234
0.681TrpAsn: 0.681 ± 0.192
0.454TrpPro: 0.454 ± 0.249
0.454TrpGln: 0.454 ± 0.211
0.757TrpArg: 0.757 ± 0.271
1.513TrpSer: 1.513 ± 0.306
0.984TrpThr: 0.984 ± 0.245
0.757TrpVal: 0.757 ± 0.195
0.0TrpTrp: 0.0 ± 0.0
0.832TrpTyr: 0.832 ± 0.223
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.178TyrAla: 3.178 ± 0.503
0.53TyrCys: 0.53 ± 0.19
2.497TyrAsp: 2.497 ± 0.38
2.119TyrGlu: 2.119 ± 0.401
2.573TyrPhe: 2.573 ± 0.441
2.27TyrGly: 2.27 ± 0.468
0.832TyrHis: 0.832 ± 0.238
2.421TyrIle: 2.421 ± 0.426
1.816TyrLys: 1.816 ± 0.376
2.876TyrLeu: 2.876 ± 0.56
1.967TyrMet: 1.967 ± 0.452
2.119TyrAsn: 2.119 ± 0.355
2.573TyrPro: 2.573 ± 0.424
1.135TyrGln: 1.135 ± 0.243
1.892TyrArg: 1.892 ± 0.389
3.481TyrSer: 3.481 ± 0.486
1.967TyrThr: 1.967 ± 0.535
2.951TyrVal: 2.951 ± 0.477
0.908TyrTrp: 0.908 ± 0.226
2.119TyrTyr: 2.119 ± 0.527
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (13216 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski