Amino acid dipepetide frequency for Zostera marina amalgavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.434AlaAla: 3.434 ± 0.794
0.687AlaCys: 0.687 ± 0.333
7.555AlaAsp: 7.555 ± 3.715
2.747AlaGlu: 2.747 ± 0.103
2.747AlaPhe: 2.747 ± 1.334
3.434AlaGly: 3.434 ± 0.436
0.687AlaHis: 0.687 ± 0.333
6.181AlaIle: 6.181 ± 0.691
4.808AlaLys: 4.808 ± 0.127
8.242AlaLeu: 8.242 ± 0.921
0.687AlaMet: 0.687 ± 0.333
2.747AlaAsn: 2.747 ± 0.103
2.747AlaPro: 2.747 ± 0.103
4.808AlaGln: 4.808 ± 2.588
6.868AlaArg: 6.868 ± 0.357
7.555AlaSer: 7.555 ± 2.485
2.747AlaThr: 2.747 ± 0.103
4.121AlaVal: 4.121 ± 0.77
2.06AlaTrp: 2.06 ± 0.23
0.687AlaTyr: 0.687 ± 0.333
0.0AlaXaa: 0.0 ± 0.0
Cys
2.06CysAla: 2.06 ± 1.0
1.374CysCys: 1.374 ± 0.564
1.374CysAsp: 1.374 ± 0.564
5.495CysGlu: 5.495 ± 1.024
0.687CysPhe: 0.687 ± 0.333
0.687CysGly: 0.687 ± 0.333
0.0CysHis: 0.0 ± 0.0
1.374CysIle: 1.374 ± 0.667
2.06CysLys: 2.06 ± 0.23
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.747CysAsn: 2.747 ± 1.127
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.747CysSer: 2.747 ± 0.103
0.0CysThr: 0.0 ± 0.0
2.06CysVal: 2.06 ± 0.23
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.181AspAla: 6.181 ± 0.691
2.747AspCys: 2.747 ± 1.127
3.434AspAsp: 3.434 ± 0.794
4.121AspGlu: 4.121 ± 1.691
2.06AspPhe: 2.06 ± 0.23
4.121AspGly: 4.121 ± 0.461
0.0AspHis: 0.0 ± 0.0
4.121AspIle: 4.121 ± 0.77
2.06AspLys: 2.06 ± 0.23
4.121AspLeu: 4.121 ± 0.77
0.0AspMet: 0.0 ± 0.0
5.495AspAsn: 5.495 ± 0.206
0.0AspPro: 0.0 ± 0.0
0.687AspGln: 0.687 ± 0.333
4.808AspArg: 4.808 ± 0.127
5.495AspSer: 5.495 ± 1.024
2.06AspThr: 2.06 ± 0.23
6.868AspVal: 6.868 ± 2.818
2.747AspTrp: 2.747 ± 0.103
2.06AspTyr: 2.06 ± 0.23
0.0AspXaa: 0.0 ± 0.0
Glu
2.06GluAla: 2.06 ± 1.0
0.0GluCys: 0.0 ± 0.0
4.121GluAsp: 4.121 ± 0.77
8.929GluGlu: 8.929 ± 0.588
0.687GluPhe: 0.687 ± 0.333
3.434GluGly: 3.434 ± 0.436
2.06GluHis: 2.06 ± 0.23
4.121GluIle: 4.121 ± 0.461
10.989GluLys: 10.989 ± 2.049
3.434GluLeu: 3.434 ± 1.667
1.374GluMet: 1.374 ± 0.667
2.747GluAsn: 2.747 ± 0.103
1.374GluPro: 1.374 ± 0.564
3.434GluGln: 3.434 ± 2.024
5.495GluArg: 5.495 ± 1.024
6.181GluSer: 6.181 ± 0.691
3.434GluThr: 3.434 ± 2.024
4.121GluVal: 4.121 ± 0.461
0.0GluTrp: 0.0 ± 0.0
2.06GluTyr: 2.06 ± 0.23
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
3.434PheCys: 3.434 ± 0.436
3.434PheAsp: 3.434 ± 0.436
1.374PheGlu: 1.374 ± 0.667
1.374PhePhe: 1.374 ± 0.564
0.0PheGly: 0.0 ± 0.0
1.374PheHis: 1.374 ± 0.564
0.687PheIle: 0.687 ± 0.333
2.06PheLys: 2.06 ± 1.461
5.495PheLeu: 5.495 ± 2.667
0.0PheMet: 0.0 ± 0.0
1.374PheAsn: 1.374 ± 0.667
2.06PhePro: 2.06 ± 1.0
0.687PheGln: 0.687 ± 0.333
7.555PheArg: 7.555 ± 0.024
1.374PheSer: 1.374 ± 0.667
0.0PheThr: 0.0 ± 0.0
4.121PheVal: 4.121 ± 0.77
0.687PheTrp: 0.687 ± 0.333
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.687GlyAla: 0.687 ± 0.897
1.374GlyCys: 1.374 ± 0.667
2.747GlyAsp: 2.747 ± 1.127
2.747GlyGlu: 2.747 ± 1.127
2.06GlyPhe: 2.06 ± 0.23
5.495GlyGly: 5.495 ± 0.206
0.687GlyHis: 0.687 ± 0.333
3.434GlyIle: 3.434 ± 0.436
4.121GlyLys: 4.121 ± 1.691
3.434GlyLeu: 3.434 ± 0.436
2.747GlyMet: 2.747 ± 0.103
2.06GlyAsn: 2.06 ± 1.0
1.374GlyPro: 1.374 ± 0.667
1.374GlyGln: 1.374 ± 0.667
4.808GlyArg: 4.808 ± 2.334
4.808GlySer: 4.808 ± 0.127
2.747GlyThr: 2.747 ± 1.334
3.434GlyVal: 3.434 ± 1.667
1.374GlyTrp: 1.374 ± 0.667
2.06GlyTyr: 2.06 ± 0.23
0.0GlyXaa: 0.0 ± 0.0
His
1.374HisAla: 1.374 ± 0.667
0.0HisCys: 0.0 ± 0.0
2.06HisAsp: 2.06 ± 1.0
0.0HisGlu: 0.0 ± 0.0
1.374HisPhe: 1.374 ± 0.667
0.687HisGly: 0.687 ± 0.897
0.0HisHis: 0.0 ± 0.0
0.687HisIle: 0.687 ± 0.333
3.434HisLys: 3.434 ± 0.794
2.747HisLeu: 2.747 ± 0.103
0.0HisMet: 0.0 ± 0.0
0.687HisAsn: 0.687 ± 0.333
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.687HisArg: 0.687 ± 0.333
0.687HisSer: 0.687 ± 0.333
0.0HisThr: 0.0 ± 0.0
0.687HisVal: 0.687 ± 0.333
0.0HisTrp: 0.0 ± 0.0
3.434HisTyr: 3.434 ± 0.794
0.0HisXaa: 0.0 ± 0.0
Ile
3.434IleAla: 3.434 ± 0.794
0.0IleCys: 0.0 ± 0.0
3.434IleAsp: 3.434 ± 0.436
4.808IleGlu: 4.808 ± 0.127
0.687IlePhe: 0.687 ± 0.897
2.747IleGly: 2.747 ± 0.103
1.374IleHis: 1.374 ± 0.667
0.0IleIle: 0.0 ± 0.0
6.868IleLys: 6.868 ± 1.588
10.302IleLeu: 10.302 ± 1.309
0.687IleMet: 0.687 ± 0.333
0.0IleAsn: 0.0 ± 0.0
2.747IlePro: 2.747 ± 1.334
1.374IleGln: 1.374 ± 0.667
3.434IleArg: 3.434 ± 0.436
2.747IleSer: 2.747 ± 0.103
3.434IleThr: 3.434 ± 0.794
3.434IleVal: 3.434 ± 1.667
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
8.242LysAla: 8.242 ± 2.152
2.747LysCys: 2.747 ± 0.103
2.06LysAsp: 2.06 ± 1.0
2.06LysGlu: 2.06 ± 1.461
2.06LysPhe: 2.06 ± 1.0
4.121LysGly: 4.121 ± 1.691
1.374LysHis: 1.374 ± 0.564
8.242LysIle: 8.242 ± 2.152
6.181LysLys: 6.181 ± 4.382
9.615LysLeu: 9.615 ± 1.485
2.06LysMet: 2.06 ± 1.036
0.687LysAsn: 0.687 ± 0.333
4.121LysPro: 4.121 ± 0.461
2.06LysGln: 2.06 ± 0.23
9.615LysArg: 9.615 ± 2.715
2.06LysSer: 2.06 ± 1.461
2.06LysThr: 2.06 ± 0.23
2.06LysVal: 2.06 ± 1.0
1.374LysTrp: 1.374 ± 0.667
5.495LysTyr: 5.495 ± 0.206
0.0LysXaa: 0.0 ± 0.0
Leu
2.747LeuAla: 2.747 ± 1.334
0.687LeuCys: 0.687 ± 0.333
4.808LeuAsp: 4.808 ± 1.103
10.989LeuGlu: 10.989 ± 0.818
4.121LeuPhe: 4.121 ± 0.77
4.121LeuGly: 4.121 ± 0.77
1.374LeuHis: 1.374 ± 0.667
3.434LeuIle: 3.434 ± 1.667
12.363LeuLys: 12.363 ± 1.382
13.049LeuLeu: 13.049 ± 0.182
1.374LeuMet: 1.374 ± 0.667
6.181LeuAsn: 6.181 ± 1.77
6.868LeuPro: 6.868 ± 0.873
4.808LeuGln: 4.808 ± 1.358
7.555LeuArg: 7.555 ± 0.024
8.929LeuSer: 8.929 ± 0.643
2.06LeuThr: 2.06 ± 1.0
3.434LeuVal: 3.434 ± 0.794
1.374LeuTrp: 1.374 ± 0.667
3.434LeuTyr: 3.434 ± 1.667
0.0LeuXaa: 0.0 ± 0.0
Met
2.06MetAla: 2.06 ± 0.23
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.374MetGlu: 1.374 ± 0.667
3.434MetPhe: 3.434 ± 0.794
0.687MetGly: 0.687 ± 0.333
0.0MetHis: 0.0 ± 0.0
0.687MetIle: 0.687 ± 0.333
0.0MetLys: 0.0 ± 0.0
4.121MetLeu: 4.121 ± 2.0
0.687MetMet: 0.687 ± 0.333
1.374MetAsn: 1.374 ± 0.667
1.374MetPro: 1.374 ± 0.564
0.687MetGln: 0.687 ± 0.333
1.374MetArg: 1.374 ± 0.667
0.687MetSer: 0.687 ± 0.333
0.0MetThr: 0.0 ± 0.0
0.687MetVal: 0.687 ± 0.333
0.0MetTrp: 0.0 ± 0.0
0.687MetTyr: 0.687 ± 0.333
0.0MetXaa: 0.0 ± 0.0
Asn
8.929AsnAla: 8.929 ± 0.588
0.687AsnCys: 0.687 ± 0.333
2.06AsnAsp: 2.06 ± 0.23
2.747AsnGlu: 2.747 ± 0.103
2.06AsnPhe: 2.06 ± 1.0
0.687AsnGly: 0.687 ± 0.333
0.687AsnHis: 0.687 ± 0.333
3.434AsnIle: 3.434 ± 0.436
2.747AsnLys: 2.747 ± 1.127
3.434AsnLeu: 3.434 ± 1.667
2.06AsnMet: 2.06 ± 1.0
0.687AsnAsn: 0.687 ± 0.333
2.06AsnPro: 2.06 ± 1.0
1.374AsnGln: 1.374 ± 0.564
2.06AsnArg: 2.06 ± 0.23
0.687AsnSer: 0.687 ± 0.333
0.0AsnThr: 0.0 ± 0.0
1.374AsnVal: 1.374 ± 0.667
0.0AsnTrp: 0.0 ± 0.0
1.374AsnTyr: 1.374 ± 0.667
0.0AsnXaa: 0.0 ± 0.0
Pro
2.747ProAla: 2.747 ± 0.103
0.0ProCys: 0.0 ± 0.0
2.06ProAsp: 2.06 ± 1.0
3.434ProGlu: 3.434 ± 0.794
1.374ProPhe: 1.374 ± 0.667
2.747ProGly: 2.747 ± 0.103
1.374ProHis: 1.374 ± 0.564
2.747ProIle: 2.747 ± 0.103
0.687ProLys: 0.687 ± 0.333
8.929ProLeu: 8.929 ± 0.643
1.374ProMet: 1.374 ± 0.667
0.0ProAsn: 0.0 ± 0.0
4.121ProPro: 4.121 ± 0.461
0.687ProGln: 0.687 ± 0.897
2.747ProArg: 2.747 ± 1.334
3.434ProSer: 3.434 ± 0.436
0.687ProThr: 0.687 ± 0.333
3.434ProVal: 3.434 ± 0.436
2.06ProTrp: 2.06 ± 0.23
0.687ProTyr: 0.687 ± 0.333
0.0ProXaa: 0.0 ± 0.0
Gln
4.121GlnAla: 4.121 ± 0.461
0.0GlnCys: 0.0 ± 0.0
2.06GlnAsp: 2.06 ± 0.23
2.747GlnGlu: 2.747 ± 1.127
2.747GlnPhe: 2.747 ± 1.334
0.687GlnGly: 0.687 ± 0.333
0.687GlnHis: 0.687 ± 0.333
0.687GlnIle: 0.687 ± 0.333
1.374GlnLys: 1.374 ± 0.564
3.434GlnLeu: 3.434 ± 0.794
0.0GlnMet: 0.0 ± 0.0
2.06GlnAsn: 2.06 ± 1.461
0.687GlnPro: 0.687 ± 0.333
0.687GlnGln: 0.687 ± 0.333
2.06GlnArg: 2.06 ± 1.0
1.374GlnSer: 1.374 ± 0.564
0.687GlnThr: 0.687 ± 0.897
2.06GlnVal: 2.06 ± 0.23
0.0GlnTrp: 0.0 ± 0.0
2.06GlnTyr: 2.06 ± 0.23
0.0GlnXaa: 0.0 ± 0.0
Arg
6.181ArgAla: 6.181 ± 0.54
1.374ArgCys: 1.374 ± 0.564
8.929ArgAsp: 8.929 ± 3.049
4.121ArgGlu: 4.121 ± 2.0
2.747ArgPhe: 2.747 ± 0.103
4.808ArgGly: 4.808 ± 2.334
0.687ArgHis: 0.687 ± 0.333
4.808ArgIle: 4.808 ± 1.358
9.615ArgLys: 9.615 ± 3.946
6.868ArgLeu: 6.868 ± 0.357
0.687ArgMet: 0.687 ± 0.333
2.06ArgAsn: 2.06 ± 1.0
4.808ArgPro: 4.808 ± 1.103
3.434ArgGln: 3.434 ± 1.667
5.495ArgArg: 5.495 ± 1.437
8.242ArgSer: 8.242 ± 0.309
2.06ArgThr: 2.06 ± 1.461
4.808ArgVal: 4.808 ± 0.127
0.687ArgTrp: 0.687 ± 0.333
0.687ArgTyr: 0.687 ± 0.333
0.0ArgXaa: 0.0 ± 0.0
Ser
4.808SerAla: 4.808 ± 0.127
1.374SerCys: 1.374 ± 0.667
4.808SerAsp: 4.808 ± 1.358
4.121SerGlu: 4.121 ± 2.921
0.687SerPhe: 0.687 ± 0.333
7.555SerGly: 7.555 ± 0.024
2.747SerHis: 2.747 ± 0.103
2.747SerIle: 2.747 ± 1.334
4.808SerLys: 4.808 ± 1.103
6.181SerLeu: 6.181 ± 1.77
2.06SerMet: 2.06 ± 0.249
1.374SerAsn: 1.374 ± 0.564
2.06SerPro: 2.06 ± 0.23
0.687SerGln: 0.687 ± 0.333
10.302SerArg: 10.302 ± 1.151
7.555SerSer: 7.555 ± 2.485
1.374SerThr: 1.374 ± 0.564
4.808SerVal: 4.808 ± 0.127
0.0SerTrp: 0.0 ± 0.0
2.747SerTyr: 2.747 ± 1.127
0.0SerXaa: 0.0 ± 0.0
Thr
4.808ThrAla: 4.808 ± 0.127
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
0.687ThrGlu: 0.687 ± 0.333
1.374ThrPhe: 1.374 ± 0.564
2.747ThrGly: 2.747 ± 0.103
0.687ThrHis: 0.687 ± 0.333
0.687ThrIle: 0.687 ± 0.333
1.374ThrLys: 1.374 ± 0.667
1.374ThrLeu: 1.374 ± 0.564
1.374ThrMet: 1.374 ± 0.667
0.0ThrAsn: 0.0 ± 0.0
2.747ThrPro: 2.747 ± 1.127
1.374ThrGln: 1.374 ± 0.564
1.374ThrArg: 1.374 ± 1.794
2.747ThrSer: 2.747 ± 0.103
0.687ThrThr: 0.687 ± 0.333
3.434ThrVal: 3.434 ± 0.436
0.687ThrTrp: 0.687 ± 0.333
1.374ThrTyr: 1.374 ± 0.564
0.0ThrXaa: 0.0 ± 0.0
Val
10.302ValAla: 10.302 ± 4.843
1.374ValCys: 1.374 ± 0.564
4.808ValAsp: 4.808 ± 1.358
4.121ValGlu: 4.121 ± 0.77
4.121ValPhe: 4.121 ± 0.77
2.747ValGly: 2.747 ± 1.334
0.687ValHis: 0.687 ± 0.333
2.747ValIle: 2.747 ± 0.103
1.374ValLys: 1.374 ± 0.667
3.434ValLeu: 3.434 ± 1.667
1.374ValMet: 1.374 ± 0.667
3.434ValAsn: 3.434 ± 0.436
4.121ValPro: 4.121 ± 0.77
1.374ValGln: 1.374 ± 0.667
4.808ValArg: 4.808 ± 0.127
3.434ValSer: 3.434 ± 0.436
2.747ValThr: 2.747 ± 1.334
2.747ValVal: 2.747 ± 0.103
1.374ValTrp: 1.374 ± 0.667
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.374TrpAla: 1.374 ± 0.564
0.687TrpCys: 0.687 ± 0.333
0.0TrpAsp: 0.0 ± 0.0
1.374TrpGlu: 1.374 ± 0.667
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.374TrpHis: 1.374 ± 0.564
0.0TrpIle: 0.0 ± 0.0
0.687TrpLys: 0.687 ± 0.333
1.374TrpLeu: 1.374 ± 0.564
0.0TrpMet: 0.0 ± 0.0
2.747TrpAsn: 2.747 ± 1.334
0.0TrpPro: 0.0 ± 0.0
0.687TrpGln: 0.687 ± 0.333
1.374TrpArg: 1.374 ± 0.667
1.374TrpSer: 1.374 ± 0.667
1.374TrpThr: 1.374 ± 0.667
0.687TrpVal: 0.687 ± 0.333
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
4.121TyrCys: 4.121 ± 1.691
3.434TyrAsp: 3.434 ± 0.794
2.06TyrGlu: 2.06 ± 1.0
0.687TyrPhe: 0.687 ± 0.333
2.06TyrGly: 2.06 ± 1.0
0.687TyrHis: 0.687 ± 0.333
0.687TyrIle: 0.687 ± 0.333
0.687TyrLys: 0.687 ± 0.333
4.121TyrLeu: 4.121 ± 0.461
0.687TyrMet: 0.687 ± 0.333
0.687TyrAsn: 0.687 ± 0.333
2.06TyrPro: 2.06 ± 0.23
0.0TyrGln: 0.0 ± 0.0
0.687TyrArg: 0.687 ± 0.333
1.374TyrSer: 1.374 ± 0.564
1.374TyrThr: 1.374 ± 0.564
2.747TyrVal: 2.747 ± 0.103
0.687TyrTrp: 0.687 ± 0.333
0.687TyrTyr: 0.687 ± 0.897
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1457 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski