Amino acid dipepetide frequency for Magnetospirillum moscoviense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.538AlaAla: 18.538 ± 0.232	1.371AlaCys: 1.371 ± 0.039	7.819AlaAsp: 7.819 ± 0.098	8.247AlaGlu: 8.247 ± 0.114	4.226AlaPhe: 4.226 ± 0.062	11.065AlaGly: 11.065 ± 0.149	2.489AlaHis: 2.489 ± 0.055	6.245AlaIle: 6.245 ± 0.085	4.729AlaLys: 4.729 ± 0.071	13.511AlaLeu: 13.511 ± 0.127	3.476AlaMet: 3.476 ± 0.058	3.055AlaAsn: 3.055 ± 0.089	5.479AlaPro: 5.479 ± 0.095	4.282AlaGln: 4.282 ± 0.073	8.902AlaArg: 8.902 ± 0.128	5.662AlaSer: 5.662 ± 0.092	5.935AlaThr: 5.935 ± 0.153	9.385AlaVal: 9.385 ± 0.108	1.735AlaTrp: 1.735 ± 0.039	2.265AlaTyr: 2.265 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.045CysAla: 1.045 ± 0.031	0.125CysCys: 0.125 ± 0.01	0.653CysAsp: 0.653 ± 0.023	0.468CysGlu: 0.468 ± 0.018	0.334CysPhe: 0.334 ± 0.017	0.994CysGly: 0.994 ± 0.033	0.325CysHis: 0.325 ± 0.018	0.386CysIle: 0.386 ± 0.022	0.272CysLys: 0.272 ± 0.017	0.947CysLeu: 0.947 ± 0.031	0.171CysMet: 0.171 ± 0.011	0.219CysAsn: 0.219 ± 0.016	0.632CysPro: 0.632 ± 0.028	0.302CysGln: 0.302 ± 0.014	0.819CysArg: 0.819 ± 0.027	0.49CysSer: 0.49 ± 0.022	0.47CysThr: 0.47 ± 0.022	0.642CysVal: 0.642 ± 0.027	0.125CysTrp: 0.125 ± 0.011	0.21CysTyr: 0.21 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.267AspAla: 6.267 ± 0.104	0.59AspCys: 0.59 ± 0.023	3.49AspAsp: 3.49 ± 0.084	3.475AspGlu: 3.475 ± 0.059	2.174AspPhe: 2.174 ± 0.05	6.156AspGly: 6.156 ± 0.133	1.514AspHis: 1.514 ± 0.04	3.293AspIle: 3.293 ± 0.055	1.997AspLys: 1.997 ± 0.048	6.376AspLeu: 6.376 ± 0.085	1.439AspMet: 1.439 ± 0.035	1.361AspAsn: 1.361 ± 0.047	3.354AspPro: 3.354 ± 0.06	2.225AspGln: 2.225 ± 0.039	4.414AspArg: 4.414 ± 0.082	2.952AspSer: 2.952 ± 0.07	2.647AspThr: 2.647 ± 0.088	3.946AspVal: 3.946 ± 0.061	1.013AspTrp: 1.013 ± 0.032	1.325AspTyr: 1.325 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.558GluAla: 7.558 ± 0.101	0.469GluCys: 0.469 ± 0.02	2.752GluAsp: 2.752 ± 0.054	2.852GluGlu: 2.852 ± 0.062	1.739GluPhe: 1.739 ± 0.042	4.078GluGly: 4.078 ± 0.064	1.067GluHis: 1.067 ± 0.034	3.098GluIle: 3.098 ± 0.065	2.097GluLys: 2.097 ± 0.052	5.563GluLeu: 5.563 ± 0.085	1.755GluMet: 1.755 ± 0.041	1.235GluAsn: 1.235 ± 0.035	2.515GluPro: 2.515 ± 0.064	2.121GluGln: 2.121 ± 0.043	4.703GluArg: 4.703 ± 0.081	2.509GluSer: 2.509 ± 0.055	3.114GluThr: 3.114 ± 0.051	4.15GluVal: 4.15 ± 0.069	0.715GluTrp: 0.715 ± 0.025	0.983GluTyr: 0.983 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.47PheAla: 4.47 ± 0.065	0.423PheCys: 0.423 ± 0.02	2.454PheAsp: 2.454 ± 0.049	1.901PheGlu: 1.901 ± 0.045	1.234PhePhe: 1.234 ± 0.034	3.236PheGly: 3.236 ± 0.052	0.778PheHis: 0.778 ± 0.028	1.428PheIle: 1.428 ± 0.039	1.112PheLys: 1.112 ± 0.032	3.429PheLeu: 3.429 ± 0.068	0.735PheMet: 0.735 ± 0.026	0.974PheAsn: 0.974 ± 0.029	1.511PhePro: 1.511 ± 0.037	1.082PheGln: 1.082 ± 0.028	2.097PheArg: 2.097 ± 0.049	1.965PheSer: 1.965 ± 0.048	2.057PheThr: 2.057 ± 0.055	2.621PheVal: 2.621 ± 0.05	0.463PheTrp: 0.463 ± 0.022	0.755PheTyr: 0.755 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.123GlyAla: 9.123 ± 0.113	1.01GlyCys: 1.01 ± 0.036	4.821GlyAsp: 4.821 ± 0.085	4.44GlyGlu: 4.44 ± 0.072	3.302GlyPhe: 3.302 ± 0.056	7.533GlyGly: 7.533 ± 0.176	2.048GlyHis: 2.048 ± 0.045	4.728GlyIle: 4.728 ± 0.063	3.42GlyLys: 3.42 ± 0.061	9.542GlyLeu: 9.542 ± 0.099	2.405GlyMet: 2.405 ± 0.057	2.105GlyAsn: 2.105 ± 0.07	3.49GlyPro: 3.49 ± 0.065	3.385GlyGln: 3.385 ± 0.052	6.517GlyArg: 6.517 ± 0.102	4.344GlySer: 4.344 ± 0.121	4.916GlyThr: 4.916 ± 0.223	5.53GlyVal: 5.53 ± 0.076	1.498GlyTrp: 1.498 ± 0.04	1.954GlyTyr: 1.954 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.371HisAla: 2.371 ± 0.045	0.265HisCys: 0.265 ± 0.015	1.31HisAsp: 1.31 ± 0.038	1.055HisGlu: 1.055 ± 0.035	0.889HisPhe: 0.889 ± 0.027	2.024HisGly: 2.024 ± 0.04	0.78HisHis: 0.78 ± 0.033	0.898HisIle: 0.898 ± 0.029	0.562HisLys: 0.562 ± 0.022	2.401HisLeu: 2.401 ± 0.054	0.486HisMet: 0.486 ± 0.02	0.465HisAsn: 0.465 ± 0.018	1.544HisPro: 1.544 ± 0.041	0.756HisGln: 0.756 ± 0.03	1.609HisArg: 1.609 ± 0.044	1.001HisSer: 1.001 ± 0.029	0.877HisThr: 0.877 ± 0.026	1.616HisVal: 1.616 ± 0.036	0.377HisTrp: 0.377 ± 0.021	0.562HisTyr: 0.562 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.302IleAla: 6.302 ± 0.075	0.493IleCys: 0.493 ± 0.022	3.862IleAsp: 3.862 ± 0.062	3.392IleGlu: 3.392 ± 0.067	1.342IlePhe: 1.342 ± 0.036	4.706IleGly: 4.706 ± 0.063	1.032IleHis: 1.032 ± 0.033	2.024IleIle: 2.024 ± 0.051	1.787IleLys: 1.787 ± 0.043	4.398IleLeu: 4.398 ± 0.075	0.925IleMet: 0.925 ± 0.034	1.421IleAsn: 1.421 ± 0.043	2.165IlePro: 2.165 ± 0.046	1.289IleGln: 1.289 ± 0.035	3.176IleArg: 3.176 ± 0.065	2.559IleSer: 2.559 ± 0.049	2.668IleThr: 2.668 ± 0.054	3.51IleVal: 3.51 ± 0.06	0.494IleTrp: 0.494 ± 0.02	0.942IleTyr: 0.942 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.797LysAla: 4.797 ± 0.073	0.215LysCys: 0.215 ± 0.014	2.13LysAsp: 2.13 ± 0.047	1.667LysGlu: 1.667 ± 0.042	0.898LysPhe: 0.898 ± 0.029	3.218LysGly: 3.218 ± 0.053	0.609LysHis: 0.609 ± 0.025	1.617LysIle: 1.617 ± 0.042	1.49LysLys: 1.49 ± 0.049	3.273LysLeu: 3.273 ± 0.058	0.905LysMet: 0.905 ± 0.03	0.885LysAsn: 0.885 ± 0.028	2.17LysPro: 2.17 ± 0.046	0.997LysGln: 0.997 ± 0.031	2.332LysArg: 2.332 ± 0.061	1.878LysSer: 1.878 ± 0.033	1.845LysThr: 1.845 ± 0.04	2.978LysVal: 2.978 ± 0.055	0.335LysTrp: 0.335 ± 0.018	0.651LysTyr: 0.651 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	16.026LeuAla: 16.026 ± 0.184	0.867LeuCys: 0.867 ± 0.033	6.478LeuAsp: 6.478 ± 0.076	5.3LeuGlu: 5.3 ± 0.079	3.539LeuPhe: 3.539 ± 0.069	8.506LeuGly: 8.506 ± 0.099	2.01LeuHis: 2.01 ± 0.044	4.634LeuIle: 4.634 ± 0.072	4.025LeuLys: 4.025 ± 0.064	9.633LeuLeu: 9.633 ± 0.132	2.527LeuMet: 2.527 ± 0.061	2.379LeuAsn: 2.379 ± 0.047	5.582LeuPro: 5.582 ± 0.086	2.407LeuGln: 2.407 ± 0.048	6.286LeuArg: 6.286 ± 0.091	6.086LeuSer: 6.086 ± 0.079	5.866LeuThr: 5.866 ± 0.117	8.396LeuVal: 8.396 ± 0.106	1.247LeuTrp: 1.247 ± 0.033	1.943LeuTyr: 1.943 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.581MetAla: 3.581 ± 0.064	0.187MetCys: 0.187 ± 0.012	1.356MetAsp: 1.356 ± 0.027	1.229MetGlu: 1.229 ± 0.034	0.731MetPhe: 0.731 ± 0.028	2.03MetGly: 2.03 ± 0.047	0.378MetHis: 0.378 ± 0.02	1.274MetIle: 1.274 ± 0.038	1.005MetLys: 1.005 ± 0.029	2.507MetLeu: 2.507 ± 0.066	0.754MetMet: 0.754 ± 0.029	0.778MetAsn: 0.778 ± 0.024	1.41MetPro: 1.41 ± 0.04	0.661MetGln: 0.661 ± 0.025	1.672MetArg: 1.672 ± 0.045	1.571MetSer: 1.571 ± 0.036	1.716MetThr: 1.716 ± 0.036	2.344MetVal: 2.344 ± 0.049	0.237MetTrp: 0.237 ± 0.016	0.303MetTyr: 0.303 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.018AsnAla: 3.018 ± 0.072	0.237AsnCys: 0.237 ± 0.016	1.435AsnAsp: 1.435 ± 0.078	1.087AsnGlu: 1.087 ± 0.034	0.838AsnPhe: 0.838 ± 0.024	2.197AsnGly: 2.197 ± 0.091	0.522AsnHis: 0.522 ± 0.02	1.196AsnIle: 1.196 ± 0.03	0.698AsnLys: 0.698 ± 0.025	2.738AsnLeu: 2.738 ± 0.05	0.545AsnMet: 0.545 ± 0.022	0.645AsnAsn: 0.645 ± 0.031	1.727AsnPro: 1.727 ± 0.031	0.816AsnGln: 0.816 ± 0.028	1.789AsnArg: 1.789 ± 0.042	1.258AsnSer: 1.258 ± 0.054	1.112AsnThr: 1.112 ± 0.066	1.798AsnVal: 1.798 ± 0.047	0.349AsnTrp: 0.349 ± 0.015	0.539AsnTyr: 0.539 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.644ProAla: 6.644 ± 0.11	0.389ProCys: 0.389 ± 0.019	3.854ProAsp: 3.854 ± 0.068	3.533ProGlu: 3.533 ± 0.065	1.822ProPhe: 1.822 ± 0.046	4.403ProGly: 4.403 ± 0.071	1.092ProHis: 1.092 ± 0.033	2.125ProIle: 2.125 ± 0.054	1.717ProLys: 1.717 ± 0.047	4.839ProLeu: 4.839 ± 0.084	1.301ProMet: 1.301 ± 0.033	1.193ProAsn: 1.193 ± 0.03	3.078ProPro: 3.078 ± 0.099	1.498ProGln: 1.498 ± 0.038	2.713ProArg: 2.713 ± 0.054	2.471ProSer: 2.471 ± 0.051	2.467ProThr: 2.467 ± 0.057	4.414ProVal: 4.414 ± 0.068	0.707ProTrp: 0.707 ± 0.029	1.0ProTyr: 1.0 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.112GlnAla: 5.112 ± 0.088	0.255GlnCys: 0.255 ± 0.016	1.516GlnAsp: 1.516 ± 0.035	1.378GlnGlu: 1.378 ± 0.036	0.982GlnPhe: 0.982 ± 0.026	2.814GlnGly: 2.814 ± 0.052	0.621GlnHis: 0.621 ± 0.025	1.576GlnIle: 1.576 ± 0.036	0.937GlnLys: 0.937 ± 0.031	3.01GlnLeu: 3.01 ± 0.056	0.903GlnMet: 0.903 ± 0.026	0.662GlnAsn: 0.662 ± 0.023	1.873GlnPro: 1.873 ± 0.042	1.015GlnGln: 1.015 ± 0.038	2.133GlnArg: 2.133 ± 0.05	1.692GlnSer: 1.692 ± 0.045	1.795GlnThr: 1.795 ± 0.049	2.87GlnVal: 2.87 ± 0.047	0.445GlnTrp: 0.445 ± 0.018	0.569GlnTyr: 0.569 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	7.889ArgAla: 7.889 ± 0.114	0.571ArgCys: 0.571 ± 0.022	3.835ArgAsp: 3.835 ± 0.064	3.634ArgGlu: 3.634 ± 0.076	2.885ArgPhe: 2.885 ± 0.043	4.048ArgGly: 4.048 ± 0.076	2.0ArgHis: 2.0 ± 0.047	3.703ArgIle: 3.703 ± 0.062	2.236ArgLys: 2.236 ± 0.058	8.854ArgLeu: 8.854 ± 0.139	2.032ArgMet: 2.032 ± 0.048	1.559ArgAsn: 1.559 ± 0.038	3.845ArgPro: 3.845 ± 0.083	2.773ArgGln: 2.773 ± 0.06	5.569ArgArg: 5.569 ± 0.104	3.224ArgSer: 3.224 ± 0.06	3.204ArgThr: 3.204 ± 0.056	5.034ArgVal: 5.034 ± 0.07	1.03ArgTrp: 1.03 ± 0.033	1.528ArgTyr: 1.528 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.89SerAla: 5.89 ± 0.115	0.501SerCys: 0.501 ± 0.021	2.941SerAsp: 2.941 ± 0.08	2.326SerGlu: 2.326 ± 0.051	2.061SerPhe: 2.061 ± 0.044	5.238SerGly: 5.238 ± 0.127	1.133SerHis: 1.133 ± 0.028	2.247SerIle: 2.247 ± 0.051	1.544SerLys: 1.544 ± 0.035	5.438SerLeu: 5.438 ± 0.068	1.305SerMet: 1.305 ± 0.034	1.219SerAsn: 1.219 ± 0.051	2.65SerPro: 2.65 ± 0.051	1.601SerGln: 1.601 ± 0.037	3.456SerArg: 3.456 ± 0.067	2.698SerSer: 2.698 ± 0.075	2.501SerThr: 2.501 ± 0.075	4.075SerVal: 4.075 ± 0.082	0.742SerTrp: 0.742 ± 0.024	1.139SerTyr: 1.139 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.072ThrAla: 6.072 ± 0.173	0.499ThrCys: 0.499 ± 0.023	2.957ThrAsp: 2.957 ± 0.076	2.766ThrGlu: 2.766 ± 0.056	1.985ThrPhe: 1.985 ± 0.063	4.999ThrGly: 4.999 ± 0.146	1.035ThrHis: 1.035 ± 0.027	3.05ThrIle: 3.05 ± 0.071	1.585ThrLys: 1.585 ± 0.043	5.662ThrLeu: 5.662 ± 0.118	1.255ThrMet: 1.255 ± 0.028	1.41ThrAsn: 1.41 ± 0.085	2.799ThrPro: 2.799 ± 0.05	1.51ThrGln: 1.51 ± 0.039	3.221ThrArg: 3.221 ± 0.061	2.413ThrSer: 2.413 ± 0.078	2.708ThrThr: 2.708 ± 0.117	4.566ThrVal: 4.566 ± 0.127	0.667ThrTrp: 0.667 ± 0.033	1.127ThrTyr: 1.127 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	10.283ValAla: 10.283 ± 0.106	0.754ValCys: 0.754 ± 0.025	4.242ValAsp: 4.242 ± 0.06	4.828ValGlu: 4.828 ± 0.077	2.495ValPhe: 2.495 ± 0.047	5.975ValGly: 5.975 ± 0.086	1.51ValHis: 1.51 ± 0.036	3.641ValIle: 3.641 ± 0.06	2.601ValLys: 2.601 ± 0.057	7.848ValLeu: 7.848 ± 0.094	2.047ValMet: 2.047 ± 0.048	2.022ValAsn: 2.022 ± 0.062	3.813ValPro: 3.813 ± 0.066	2.108ValGln: 2.108 ± 0.05	5.022ValArg: 5.022 ± 0.069	4.06ValSer: 4.06 ± 0.08	4.759ValThr: 4.759 ± 0.125	7.017ValVal: 7.017 ± 0.091	0.937ValTrp: 0.937 ± 0.03	1.358ValTyr: 1.358 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.383TrpAla: 1.383 ± 0.037	0.16TrpCys: 0.16 ± 0.011	0.717TrpAsp: 0.717 ± 0.024	0.584TrpGlu: 0.584 ± 0.022	0.445TrpPhe: 0.445 ± 0.018	0.966TrpGly: 0.966 ± 0.031	0.384TrpHis: 0.384 ± 0.02	0.599TrpIle: 0.599 ± 0.026	0.5TrpLys: 0.5 ± 0.022	1.707TrpLeu: 1.707 ± 0.042	0.359TrpMet: 0.359 ± 0.018	0.423TrpAsn: 0.423 ± 0.02	0.65TrpPro: 0.65 ± 0.025	0.596TrpGln: 0.596 ± 0.024	1.272TrpArg: 1.272 ± 0.036	0.763TrpSer: 0.763 ± 0.025	0.691TrpThr: 0.691 ± 0.023	0.961TrpVal: 0.961 ± 0.031	0.228TrpTrp: 0.228 ± 0.015	0.285TrpTyr: 0.285 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.046TyrAla: 2.046 ± 0.041	0.243TyrCys: 0.243 ± 0.014	1.384TyrAsp: 1.384 ± 0.037	0.913TyrGlu: 0.913 ± 0.028	0.804TyrPhe: 0.804 ± 0.029	1.93TyrGly: 1.93 ± 0.041	0.522TyrHis: 0.522 ± 0.019	0.722TyrIle: 0.722 ± 0.023	0.576TyrLys: 0.576 ± 0.025	2.061TyrLeu: 2.061 ± 0.042	0.399TyrMet: 0.399 ± 0.021	0.533TyrAsn: 0.533 ± 0.026	0.975TyrPro: 0.975 ± 0.03	0.734TyrGln: 0.734 ± 0.024	1.752TyrArg: 1.752 ± 0.044	1.109TyrSer: 1.109 ± 0.04	0.939TyrThr: 0.939 ± 0.037	1.465TyrVal: 1.465 ± 0.037	0.331TyrTrp: 0.331 ± 0.017	0.525TyrTyr: 0.525 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3747 proteins (1212731 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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