Amino acid dipepetide frequency for Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.449AlaAla: 7.449 ± 0.134	1.988AlaCys: 1.988 ± 0.062	4.23AlaAsp: 4.23 ± 0.047	4.965AlaGlu: 4.965 ± 0.091	2.631AlaPhe: 2.631 ± 0.035	4.388AlaGly: 4.388 ± 0.07	1.756AlaHis: 1.756 ± 0.025	4.632AlaIle: 4.632 ± 0.045	3.793AlaLys: 3.793 ± 0.045	9.013AlaLeu: 9.013 ± 0.095	1.735AlaMet: 1.735 ± 0.026	3.128AlaAsn: 3.128 ± 0.039	3.541AlaPro: 3.541 ± 0.044	3.212AlaGln: 3.212 ± 0.055	4.144AlaArg: 4.144 ± 0.062	7.105AlaSer: 7.105 ± 0.05	4.709AlaThr: 4.709 ± 0.046	4.756AlaVal: 4.756 ± 0.048	0.437AlaTrp: 0.437 ± 0.013	2.344AlaTyr: 2.344 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	1.975CysAla: 1.975 ± 0.066	0.439CysCys: 0.439 ± 0.015	1.239CysAsp: 1.239 ± 0.036	1.309CysGlu: 1.309 ± 0.052	0.821CysPhe: 0.821 ± 0.02	1.335CysGly: 1.335 ± 0.038	0.446CysHis: 0.446 ± 0.014	1.559CysIle: 1.559 ± 0.033	1.51CysLys: 1.51 ± 0.06	2.244CysLeu: 2.244 ± 0.037	0.51CysMet: 0.51 ± 0.015	1.158CysAsn: 1.158 ± 0.044	1.111CysPro: 1.111 ± 0.033	0.745CysGln: 0.745 ± 0.025	1.102CysArg: 1.102 ± 0.025	2.22CysSer: 2.22 ± 0.049	2.296CysThr: 2.296 ± 0.092	1.791CysVal: 1.791 ± 0.057	0.181CysTrp: 0.181 ± 0.008	0.873CysTyr: 0.873 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	4.555AspAla: 4.555 ± 0.073	1.2AspCys: 1.2 ± 0.033	3.079AspAsp: 3.079 ± 0.041	3.338AspGlu: 3.338 ± 0.052	1.956AspPhe: 1.956 ± 0.029	3.45AspGly: 3.45 ± 0.062	1.074AspHis: 1.074 ± 0.021	3.498AspIle: 3.498 ± 0.037	2.828AspLys: 2.828 ± 0.042	5.434AspLeu: 5.434 ± 0.054	1.258AspMet: 1.258 ± 0.02	2.309AspAsn: 2.309 ± 0.034	2.698AspPro: 2.698 ± 0.042	1.802AspGln: 1.802 ± 0.034	2.517AspArg: 2.517 ± 0.036	4.705AspSer: 4.705 ± 0.044	3.486AspThr: 3.486 ± 0.037	3.322AspVal: 3.322 ± 0.038	0.365AspTrp: 0.365 ± 0.011	1.75AspTyr: 1.75 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.311GluAla: 5.311 ± 0.097	1.491GluCys: 1.491 ± 0.043	3.202GluAsp: 3.202 ± 0.046	4.172GluGlu: 4.172 ± 0.058	1.762GluPhe: 1.762 ± 0.029	2.804GluGly: 2.804 ± 0.052	1.564GluHis: 1.564 ± 0.02	3.292GluIle: 3.292 ± 0.045	3.573GluLys: 3.573 ± 0.051	6.731GluLeu: 6.731 ± 0.074	1.238GluMet: 1.238 ± 0.023	2.374GluAsn: 2.374 ± 0.035	2.166GluPro: 2.166 ± 0.035	2.744GluGln: 2.744 ± 0.043	3.426GluArg: 3.426 ± 0.052	4.406GluSer: 4.406 ± 0.04	3.301GluThr: 3.301 ± 0.039	3.106GluVal: 3.106 ± 0.038	0.341GluTrp: 0.341 ± 0.011	1.97GluTyr: 1.97 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	2.305PheAla: 2.305 ± 0.03	0.869PheCys: 0.869 ± 0.02	1.862PheAsp: 1.862 ± 0.027	1.668PheGlu: 1.668 ± 0.025	1.454PhePhe: 1.454 ± 0.028	1.838PheGly: 1.838 ± 0.028	0.727PheHis: 0.727 ± 0.017	2.172PheIle: 2.172 ± 0.033	1.597PheLys: 1.597 ± 0.023	4.024PheLeu: 4.024 ± 0.049	0.764PheMet: 0.764 ± 0.018	1.553PheAsn: 1.553 ± 0.024	1.476PhePro: 1.476 ± 0.026	1.137PheGln: 1.137 ± 0.021	1.612PheArg: 1.612 ± 0.025	3.623PheSer: 3.623 ± 0.048	2.328PheThr: 2.328 ± 0.032	2.235PheVal: 2.235 ± 0.032	0.237PheTrp: 0.237 ± 0.009	1.403PheTyr: 1.403 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	3.849GlyAla: 3.849 ± 0.05	1.644GlyCys: 1.644 ± 0.071	2.834GlyAsp: 2.834 ± 0.046	2.596GlyGlu: 2.596 ± 0.044	2.018GlyPhe: 2.018 ± 0.035	3.174GlyGly: 3.174 ± 0.06	1.477GlyHis: 1.477 ± 0.028	2.995GlyIle: 2.995 ± 0.037	2.827GlyLys: 2.827 ± 0.04	4.954GlyLeu: 4.954 ± 0.047	1.243GlyMet: 1.243 ± 0.021	2.138GlyAsn: 2.138 ± 0.041	2.077GlyPro: 2.077 ± 0.037	1.841GlyGln: 1.841 ± 0.044	2.691GlyArg: 2.691 ± 0.035	4.902GlySer: 4.902 ± 0.046	3.451GlyThr: 3.451 ± 0.052	3.381GlyVal: 3.381 ± 0.041	0.452GlyTrp: 0.452 ± 0.014	2.165GlyTyr: 2.165 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	1.856HisAla: 1.856 ± 0.026	0.532HisCys: 0.532 ± 0.019	1.151HisAsp: 1.151 ± 0.021	1.394HisGlu: 1.394 ± 0.022	0.815HisPhe: 0.815 ± 0.015	1.384HisGly: 1.384 ± 0.023	0.575HisHis: 0.575 ± 0.015	1.532HisIle: 1.532 ± 0.023	1.156HisLys: 1.156 ± 0.023	2.434HisLeu: 2.434 ± 0.031	0.56HisMet: 0.56 ± 0.014	1.026HisAsn: 1.026 ± 0.018	1.177HisPro: 1.177 ± 0.02	0.879HisGln: 0.879 ± 0.02	1.332HisArg: 1.332 ± 0.024	2.144HisSer: 2.144 ± 0.029	1.533HisThr: 1.533 ± 0.025	1.421HisVal: 1.421 ± 0.021	0.15HisTrp: 0.15 ± 0.007	0.813HisTyr: 0.813 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.373IleAla: 4.373 ± 0.046	1.437IleCys: 1.437 ± 0.028	3.542IleAsp: 3.542 ± 0.036	3.263IleGlu: 3.263 ± 0.039	2.198IlePhe: 2.198 ± 0.034	2.619IleGly: 2.619 ± 0.032	1.351IleHis: 1.351 ± 0.022	3.102IleIle: 3.102 ± 0.043	2.851IleLys: 2.851 ± 0.034	6.053IleLeu: 6.053 ± 0.057	1.09IleMet: 1.09 ± 0.02	2.597IleAsn: 2.597 ± 0.028	2.815IlePro: 2.815 ± 0.032	2.199IleGln: 2.199 ± 0.03	2.902IleArg: 2.902 ± 0.033	5.555IleSer: 5.555 ± 0.053	3.418IleThr: 3.418 ± 0.036	3.493IleVal: 3.493 ± 0.036	0.404IleTrp: 0.404 ± 0.01	2.089IleTyr: 2.089 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.113LysAla: 4.113 ± 0.051	1.314LysCys: 1.314 ± 0.053	3.226LysAsp: 3.226 ± 0.043	3.746LysGlu: 3.746 ± 0.048	1.278LysPhe: 1.278 ± 0.023	2.52LysGly: 2.52 ± 0.036	1.345LysHis: 1.345 ± 0.022	2.61LysIle: 2.61 ± 0.034	3.06LysLys: 3.06 ± 0.05	5.082LysLeu: 5.082 ± 0.056	1.118LysMet: 1.118 ± 0.02	2.026LysAsn: 2.026 ± 0.025	2.083LysPro: 2.083 ± 0.029	2.453LysGln: 2.453 ± 0.035	3.064LysArg: 3.064 ± 0.037	3.792LysSer: 3.792 ± 0.048	3.353LysThr: 3.353 ± 0.047	2.686LysVal: 2.686 ± 0.032	0.284LysTrp: 0.284 ± 0.01	1.801LysTyr: 1.801 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	8.148LeuAla: 8.148 ± 0.076	2.453LeuCys: 2.453 ± 0.034	5.479LeuAsp: 5.479 ± 0.049	6.303LeuGlu: 6.303 ± 0.081	3.892LeuPhe: 3.892 ± 0.056	4.618LeuGly: 4.618 ± 0.044	2.688LeuHis: 2.688 ± 0.036	5.27LeuIle: 5.27 ± 0.051	5.214LeuLys: 5.214 ± 0.047	12.139LeuLeu: 12.139 ± 0.117	2.853LeuMet: 2.853 ± 0.057	3.922LeuAsn: 3.922 ± 0.042	4.88LeuPro: 4.88 ± 0.048	4.818LeuGln: 4.818 ± 0.058	6.017LeuArg: 6.017 ± 0.062	10.304LeuSer: 10.304 ± 0.082	6.265LeuThr: 6.265 ± 0.056	5.906LeuVal: 5.906 ± 0.057	0.642LeuTrp: 0.642 ± 0.014	3.295LeuTyr: 3.295 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	1.698MetAla: 1.698 ± 0.029	0.47MetCys: 0.47 ± 0.015	1.183MetAsp: 1.183 ± 0.019	1.268MetGlu: 1.268 ± 0.022	0.712MetPhe: 0.712 ± 0.015	1.072MetGly: 1.072 ± 0.021	0.719MetHis: 0.719 ± 0.015	1.201MetIle: 1.201 ± 0.021	1.123MetLys: 1.123 ± 0.019	2.49MetLeu: 2.49 ± 0.031	0.495MetMet: 0.495 ± 0.016	0.922MetAsn: 0.922 ± 0.018	0.965MetPro: 0.965 ± 0.018	1.119MetGln: 1.119 ± 0.021	1.29MetArg: 1.29 ± 0.022	1.873MetSer: 1.873 ± 0.024	1.341MetThr: 1.341 ± 0.023	1.189MetVal: 1.189 ± 0.02	0.167MetTrp: 0.167 ± 0.008	0.776MetTyr: 0.776 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.056AsnAla: 3.056 ± 0.038	1.02AsnCys: 1.02 ± 0.035	2.128AsnAsp: 2.128 ± 0.033	2.295AsnGlu: 2.295 ± 0.033	1.284AsnPhe: 1.284 ± 0.026	2.529AsnGly: 2.529 ± 0.057	0.819AsnHis: 0.819 ± 0.016	2.715AsnIle: 2.715 ± 0.036	2.231AsnLys: 2.231 ± 0.036	3.95AsnLeu: 3.95 ± 0.037	0.965AsnMet: 0.965 ± 0.019	1.901AsnAsn: 1.901 ± 0.027	2.12AsnPro: 2.12 ± 0.042	1.425AsnGln: 1.425 ± 0.025	1.954AsnArg: 1.954 ± 0.025	3.494AsnSer: 3.494 ± 0.044	2.846AsnThr: 2.846 ± 0.044	2.425AsnVal: 2.425 ± 0.036	0.254AsnTrp: 0.254 ± 0.011	1.425AsnTyr: 1.425 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	3.5ProAla: 3.5 ± 0.051	0.892ProCys: 0.892 ± 0.024	2.594ProAsp: 2.594 ± 0.039	2.881ProGlu: 2.881 ± 0.036	1.611ProPhe: 1.611 ± 0.029	2.642ProGly: 2.642 ± 0.047	1.105ProHis: 1.105 ± 0.021	2.521ProIle: 2.521 ± 0.032	1.949ProLys: 1.949 ± 0.032	4.57ProLeu: 4.57 ± 0.05	0.798ProMet: 0.798 ± 0.016	1.858ProAsn: 1.858 ± 0.043	2.788ProPro: 2.788 ± 0.042	1.898ProGln: 1.898 ± 0.03	2.226ProArg: 2.226 ± 0.028	4.72ProSer: 4.72 ± 0.056	2.895ProThr: 2.895 ± 0.037	2.98ProVal: 2.98 ± 0.038	0.288ProTrp: 0.288 ± 0.011	1.546ProTyr: 1.546 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.153GlnAla: 3.153 ± 0.044	0.995GlnCys: 0.995 ± 0.044	2.022GlnAsp: 2.022 ± 0.03	2.542GlnGlu: 2.542 ± 0.038	1.181GlnPhe: 1.181 ± 0.023	1.923GlnGly: 1.923 ± 0.03	1.044GlnHis: 1.044 ± 0.021	2.158GlnIle: 2.158 ± 0.026	2.219GlnLys: 2.219 ± 0.039	4.434GlnLeu: 4.434 ± 0.058	0.877GlnMet: 0.877 ± 0.019	1.643GlnAsn: 1.643 ± 0.03	1.803GlnPro: 1.803 ± 0.034	2.197GlnGln: 2.197 ± 0.041	2.463GlnArg: 2.463 ± 0.037	3.406GlnSer: 3.406 ± 0.042	2.6GlnThr: 2.6 ± 0.047	1.999GlnVal: 1.999 ± 0.03	0.239GlnTrp: 0.239 ± 0.009	1.302GlnTyr: 1.302 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	4.18ArgAla: 4.18 ± 0.05	1.245ArgCys: 1.245 ± 0.033	2.861ArgAsp: 2.861 ± 0.039	3.249ArgGlu: 3.249 ± 0.048	1.852ArgPhe: 1.852 ± 0.027	2.621ArgGly: 2.621 ± 0.035	1.325ArgHis: 1.325 ± 0.022	3.09ArgIle: 3.09 ± 0.038	2.71ArgLys: 2.71 ± 0.039	5.64ArgLeu: 5.64 ± 0.055	1.163ArgMet: 1.163 ± 0.023	2.08ArgAsn: 2.08 ± 0.028	2.392ArgPro: 2.392 ± 0.034	2.242ArgGln: 2.242 ± 0.03	3.382ArgArg: 3.382 ± 0.043	4.484ArgSer: 4.484 ± 0.05	3.154ArgThr: 3.154 ± 0.036	2.873ArgVal: 2.873 ± 0.035	0.328ArgTrp: 0.328 ± 0.012	1.873ArgTyr: 1.873 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	7.1SerAla: 7.1 ± 0.056	2.056SerCys: 2.056 ± 0.055	4.66SerAsp: 4.66 ± 0.047	4.557SerGlu: 4.557 ± 0.045	3.453SerPhe: 3.453 ± 0.042	5.067SerGly: 5.067 ± 0.051	2.0SerHis: 2.0 ± 0.027	5.672SerIle: 5.672 ± 0.056	4.376SerLys: 4.376 ± 0.042	9.523SerLeu: 9.523 ± 0.083	2.047SerMet: 2.047 ± 0.027	3.755SerAsn: 3.755 ± 0.043	4.191SerPro: 4.191 ± 0.046	3.441SerGln: 3.441 ± 0.044	4.435SerArg: 4.435 ± 0.048	9.766SerSer: 9.766 ± 0.099	6.469SerThr: 6.469 ± 0.064	5.737SerVal: 5.737 ± 0.056	0.515SerTrp: 0.515 ± 0.011	2.726SerTyr: 2.726 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.853ThrAla: 5.853 ± 0.072	2.078ThrCys: 2.078 ± 0.103	3.674ThrAsp: 3.674 ± 0.04	3.792ThrGlu: 3.792 ± 0.037	2.039ThrPhe: 2.039 ± 0.036	3.739ThrGly: 3.739 ± 0.056	1.456ThrHis: 1.456 ± 0.029	3.739ThrIle: 3.739 ± 0.04	3.077ThrLys: 3.077 ± 0.039	6.125ThrLeu: 6.125 ± 0.05	1.284ThrMet: 1.284 ± 0.021	2.627ThrAsn: 2.627 ± 0.034	3.34ThrPro: 3.34 ± 0.045	2.337ThrGln: 2.337 ± 0.039	3.005ThrArg: 3.005 ± 0.036	5.691ThrSer: 5.691 ± 0.057	4.19ThrThr: 4.19 ± 0.044	3.812ThrVal: 3.812 ± 0.038	0.337ThrTrp: 0.337 ± 0.011	1.862ThrTyr: 1.862 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	4.521ValAla: 4.521 ± 0.039	1.761ValCys: 1.761 ± 0.049	3.515ValAsp: 3.515 ± 0.035	3.442ValGlu: 3.442 ± 0.041	2.274ValPhe: 2.274 ± 0.034	2.908ValGly: 2.908 ± 0.041	1.505ValHis: 1.505 ± 0.023	3.227ValIle: 3.227 ± 0.041	2.744ValLys: 2.744 ± 0.035	6.139ValLeu: 6.139 ± 0.061	1.14ValMet: 1.14 ± 0.021	1.97ValAsn: 1.97 ± 0.025	3.018ValPro: 3.018 ± 0.034	2.373ValGln: 2.373 ± 0.031	3.059ValArg: 3.059 ± 0.037	5.748ValSer: 5.748 ± 0.049	3.643ValThr: 3.643 ± 0.043	3.695ValVal: 3.695 ± 0.04	0.405ValTrp: 0.405 ± 0.01	1.977ValTyr: 1.977 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	0.464TrpAla: 0.464 ± 0.013	0.151TrpCys: 0.151 ± 0.007	0.313TrpAsp: 0.313 ± 0.01	0.298TrpGlu: 0.298 ± 0.009	0.33TrpPhe: 0.33 ± 0.011	0.282TrpGly: 0.282 ± 0.01	0.15TrpHis: 0.15 ± 0.007	0.39TrpIle: 0.39 ± 0.014	0.365TrpLys: 0.365 ± 0.01	0.599TrpLeu: 0.599 ± 0.015	0.157TrpMet: 0.157 ± 0.008	0.287TrpAsn: 0.287 ± 0.009	0.257TrpPro: 0.257 ± 0.009	0.2TrpGln: 0.2 ± 0.009	0.395TrpArg: 0.395 ± 0.011	0.596TrpSer: 0.596 ± 0.014	0.472TrpThr: 0.472 ± 0.016	0.333TrpVal: 0.333 ± 0.011	0.091TrpTrp: 0.091 ± 0.006	0.218TrpTyr: 0.218 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.497TyrAla: 2.497 ± 0.031	0.828TyrCys: 0.828 ± 0.02	1.827TyrAsp: 1.827 ± 0.028	1.898TyrGlu: 1.898 ± 0.027	1.322TyrPhe: 1.322 ± 0.026	1.797TyrGly: 1.797 ± 0.03	0.739TyrHis: 0.739 ± 0.017	1.972TyrIle: 1.972 ± 0.03	1.752TyrLys: 1.752 ± 0.026	3.529TyrLeu: 3.529 ± 0.043	0.78TyrMet: 0.78 ± 0.017	1.562TyrAsn: 1.562 ± 0.025	1.363TyrPro: 1.363 ± 0.019	1.139TyrGln: 1.139 ± 0.022	1.728TyrArg: 1.728 ± 0.028	3.012TyrSer: 3.012 ± 0.038	2.309TyrThr: 2.309 ± 0.034	1.925TyrVal: 1.925 ± 0.029	0.229TyrTrp: 0.229 ± 0.008	1.37TyrTyr: 1.37 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4900 proteins (3121753 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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