Amino acid dipepetide frequency for Corynebacterium uterequi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.357AlaAla: 18.357 ± 0.25	0.999AlaCys: 0.999 ± 0.037	7.856AlaAsp: 7.856 ± 0.11	8.458AlaGlu: 8.458 ± 0.12	3.706AlaPhe: 3.706 ± 0.075	11.221AlaGly: 11.221 ± 0.146	2.674AlaHis: 2.674 ± 0.068	5.537AlaIle: 5.537 ± 0.093	3.258AlaLys: 3.258 ± 0.086	12.421AlaLeu: 12.421 ± 0.156	2.788AlaMet: 2.788 ± 0.063	2.632AlaAsn: 2.632 ± 0.072	5.887AlaPro: 5.887 ± 0.134	3.954AlaGln: 3.954 ± 0.083	7.947AlaArg: 7.947 ± 0.15	6.666AlaSer: 6.666 ± 0.116	7.755AlaThr: 7.755 ± 0.116	10.891AlaVal: 10.891 ± 0.146	1.665AlaTrp: 1.665 ± 0.047	2.582AlaTyr: 2.582 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	0.88CysAla: 0.88 ± 0.04	0.071CysCys: 0.071 ± 0.013	0.427CysAsp: 0.427 ± 0.026	0.409CysGlu: 0.409 ± 0.028	0.228CysPhe: 0.228 ± 0.019	0.757CysGly: 0.757 ± 0.033	0.178CysHis: 0.178 ± 0.016	0.269CysIle: 0.269 ± 0.02	0.103CysLys: 0.103 ± 0.012	0.598CysLeu: 0.598 ± 0.031	0.106CysMet: 0.106 ± 0.012	0.139CysAsn: 0.139 ± 0.013	0.416CysPro: 0.416 ± 0.029	0.23CysGln: 0.23 ± 0.019	0.433CysArg: 0.433 ± 0.029	0.438CysSer: 0.438 ± 0.027	0.416CysThr: 0.416 ± 0.029	0.603CysVal: 0.603 ± 0.029	0.095CysTrp: 0.095 ± 0.011	0.177CysTyr: 0.177 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.815AspAla: 8.815 ± 0.139	0.335AspCys: 0.335 ± 0.022	4.153AspAsp: 4.153 ± 0.095	4.036AspGlu: 4.036 ± 0.082	1.88AspPhe: 1.88 ± 0.057	5.686AspGly: 5.686 ± 0.095	1.377AspHis: 1.377 ± 0.042	2.912AspIle: 2.912 ± 0.066	1.425AspLys: 1.425 ± 0.04	5.462AspLeu: 5.462 ± 0.101	1.113AspMet: 1.113 ± 0.038	1.58AspAsn: 1.58 ± 0.052	3.84AspPro: 3.84 ± 0.086	1.652AspGln: 1.652 ± 0.047	3.624AspArg: 3.624 ± 0.076	2.88AspSer: 2.88 ± 0.064	3.36AspThr: 3.36 ± 0.066	5.25AspVal: 5.25 ± 0.104	0.71AspTrp: 0.71 ± 0.032	1.652AspTyr: 1.652 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	6.915GluAla: 6.915 ± 0.126	0.322GluCys: 0.322 ± 0.021	3.424GluAsp: 3.424 ± 0.071	3.779GluGlu: 3.779 ± 0.098	1.982GluPhe: 1.982 ± 0.057	3.911GluGly: 3.911 ± 0.086	1.58GluHis: 1.58 ± 0.051	3.062GluIle: 3.062 ± 0.076	1.854GluLys: 1.854 ± 0.061	6.956GluLeu: 6.956 ± 0.103	1.2GluMet: 1.2 ± 0.043	1.347GluAsn: 1.347 ± 0.043	2.956GluPro: 2.956 ± 0.091	2.468GluGln: 2.468 ± 0.055	4.27GluArg: 4.27 ± 0.088	2.818GluSer: 2.818 ± 0.072	2.835GluThr: 2.835 ± 0.07	4.955GluVal: 4.955 ± 0.099	0.711GluTrp: 0.711 ± 0.035	1.26GluTyr: 1.26 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.988PheAla: 3.988 ± 0.069	0.22PheCys: 0.22 ± 0.02	2.37PheAsp: 2.37 ± 0.068	1.617PheGlu: 1.617 ± 0.047	1.236PhePhe: 1.236 ± 0.047	3.441PheGly: 3.441 ± 0.078	0.686PheHis: 0.686 ± 0.035	1.474PheIle: 1.474 ± 0.052	0.644PheLys: 0.644 ± 0.03	2.839PheLeu: 2.839 ± 0.074	0.592PheMet: 0.592 ± 0.034	0.891PheAsn: 0.891 ± 0.035	1.397PhePro: 1.397 ± 0.044	0.732PheGln: 0.732 ± 0.029	1.644PheArg: 1.644 ± 0.043	2.033PheSer: 2.033 ± 0.055	1.965PheThr: 1.965 ± 0.053	2.654PheVal: 2.654 ± 0.069	0.413PheTrp: 0.413 ± 0.029	0.804PheTyr: 0.804 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.388GlyAla: 9.388 ± 0.144	0.774GlyCys: 0.774 ± 0.036	4.723GlyAsp: 4.723 ± 0.082	5.243GlyGlu: 5.243 ± 0.112	3.129GlyPhe: 3.129 ± 0.072	6.844GlyGly: 6.844 ± 0.117	1.94GlyHis: 1.94 ± 0.056	4.333GlyIle: 4.333 ± 0.088	2.42GlyLys: 2.42 ± 0.063	8.45GlyLeu: 8.45 ± 0.137	2.131GlyMet: 2.131 ± 0.054	1.928GlyAsn: 1.928 ± 0.055	3.453GlyPro: 3.453 ± 0.073	2.731GlyGln: 2.731 ± 0.061	5.649GlyArg: 5.649 ± 0.107	4.979GlySer: 4.979 ± 0.095	5.186GlyThr: 5.186 ± 0.091	7.91GlyVal: 7.91 ± 0.109	1.409GlyTrp: 1.409 ± 0.042	2.319GlyTyr: 2.319 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	2.383HisAla: 2.383 ± 0.07	0.16HisCys: 0.16 ± 0.015	1.39HisAsp: 1.39 ± 0.042	1.229HisGlu: 1.229 ± 0.042	0.651HisPhe: 0.651 ± 0.028	1.988HisGly: 1.988 ± 0.06	0.65HisHis: 0.65 ± 0.03	0.951HisIle: 0.951 ± 0.042	0.362HisLys: 0.362 ± 0.024	2.162HisLeu: 2.162 ± 0.058	0.391HisMet: 0.391 ± 0.022	0.594HisAsn: 0.594 ± 0.029	1.634HisPro: 1.634 ± 0.055	0.689HisGln: 0.689 ± 0.031	1.758HisArg: 1.758 ± 0.047	1.182HisSer: 1.182 ± 0.035	1.269HisThr: 1.269 ± 0.045	1.701HisVal: 1.701 ± 0.052	0.251HisTrp: 0.251 ± 0.02	0.594HisTyr: 0.594 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.389IleAla: 6.389 ± 0.098	0.324IleCys: 0.324 ± 0.018	3.719IleAsp: 3.719 ± 0.074	2.731IleGlu: 2.731 ± 0.068	1.35IlePhe: 1.35 ± 0.046	4.274IleGly: 4.274 ± 0.087	0.99IleHis: 0.99 ± 0.038	2.599IleIle: 2.599 ± 0.062	1.164IleLys: 1.164 ± 0.048	3.876IleLeu: 3.876 ± 0.079	0.902IleMet: 0.902 ± 0.041	1.378IleAsn: 1.378 ± 0.048	2.526IlePro: 2.526 ± 0.063	0.967IleGln: 0.967 ± 0.034	2.508IleArg: 2.508 ± 0.063	2.583IleSer: 2.583 ± 0.065	3.214IleThr: 3.214 ± 0.067	4.526IleVal: 4.526 ± 0.102	0.409IleTrp: 0.409 ± 0.023	0.951IleTyr: 0.951 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	3.123LysAla: 3.123 ± 0.088	0.096LysCys: 0.096 ± 0.01	1.602LysAsp: 1.602 ± 0.059	1.513LysGlu: 1.513 ± 0.057	0.697LysPhe: 0.697 ± 0.034	1.736LysGly: 1.736 ± 0.061	0.533LysHis: 0.533 ± 0.027	1.287LysIle: 1.287 ± 0.048	1.322LysLys: 1.322 ± 0.056	2.427LysLeu: 2.427 ± 0.06	0.582LysMet: 0.582 ± 0.03	0.838LysAsn: 0.838 ± 0.042	1.449LysPro: 1.449 ± 0.068	0.855LysGln: 0.855 ± 0.038	1.751LysArg: 1.751 ± 0.053	1.372LysSer: 1.372 ± 0.048	1.413LysThr: 1.413 ± 0.057	2.182LysVal: 2.182 ± 0.058	0.273LysTrp: 0.273 ± 0.02	0.575LysTyr: 0.575 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.484LeuAla: 13.484 ± 0.174	0.69LeuCys: 0.69 ± 0.032	6.365LeuAsp: 6.365 ± 0.1	4.295LeuGlu: 4.295 ± 0.086	2.798LeuPhe: 2.798 ± 0.065	8.81LeuGly: 8.81 ± 0.131	1.962LeuHis: 1.962 ± 0.054	4.66LeuIle: 4.66 ± 0.102	2.448LeuLys: 2.448 ± 0.073	9.51LeuLeu: 9.51 ± 0.149	1.971LeuMet: 1.971 ± 0.051	2.397LeuAsn: 2.397 ± 0.065	5.452LeuPro: 5.452 ± 0.096	2.242LeuGln: 2.242 ± 0.057	6.756LeuArg: 6.756 ± 0.124	6.329LeuSer: 6.329 ± 0.085	6.383LeuThr: 6.383 ± 0.09	8.195LeuVal: 8.195 ± 0.123	1.166LeuTrp: 1.166 ± 0.046	1.848LeuTyr: 1.848 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.658MetAla: 2.658 ± 0.068	0.145MetCys: 0.145 ± 0.014	0.972MetAsp: 0.972 ± 0.038	0.855MetGlu: 0.855 ± 0.041	0.688MetPhe: 0.688 ± 0.028	1.592MetGly: 1.592 ± 0.052	0.372MetHis: 0.372 ± 0.023	1.134MetIle: 1.134 ± 0.039	0.639MetLys: 0.639 ± 0.029	2.056MetLeu: 2.056 ± 0.06	0.445MetMet: 0.445 ± 0.024	0.622MetAsn: 0.622 ± 0.03	1.148MetPro: 1.148 ± 0.046	0.536MetGln: 0.536 ± 0.026	1.257MetArg: 1.257 ± 0.046	1.66MetSer: 1.66 ± 0.046	1.809MetThr: 1.809 ± 0.054	1.765MetVal: 1.765 ± 0.051	0.259MetTrp: 0.259 ± 0.02	0.395MetTyr: 0.395 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.863AsnAla: 2.863 ± 0.064	0.164AsnCys: 0.164 ± 0.016	1.351AsnAsp: 1.351 ± 0.047	1.293AsnGlu: 1.293 ± 0.047	0.749AsnPhe: 0.749 ± 0.032	1.957AsnGly: 1.957 ± 0.069	0.561AsnHis: 0.561 ± 0.029	1.218AsnIle: 1.218 ± 0.043	0.74AsnLys: 0.74 ± 0.036	2.354AsnLeu: 2.354 ± 0.067	0.484AsnMet: 0.484 ± 0.028	0.736AsnAsn: 0.736 ± 0.032	1.979AsnPro: 1.979 ± 0.062	0.806AsnGln: 0.806 ± 0.034	1.532AsnArg: 1.532 ± 0.051	1.357AsnSer: 1.357 ± 0.046	1.415AsnThr: 1.415 ± 0.043	1.848AsnVal: 1.848 ± 0.059	0.373AsnTrp: 0.373 ± 0.023	0.745AsnTyr: 0.745 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	6.949ProAla: 6.949 ± 0.147	0.251ProCys: 0.251 ± 0.022	3.346ProAsp: 3.346 ± 0.083	4.253ProGlu: 4.253 ± 0.088	1.495ProPhe: 1.495 ± 0.045	4.942ProGly: 4.942 ± 0.094	1.14ProHis: 1.14 ± 0.044	1.992ProIle: 1.992 ± 0.056	1.395ProLys: 1.395 ± 0.055	4.437ProLeu: 4.437 ± 0.08	1.01ProMet: 1.01 ± 0.038	1.418ProAsn: 1.418 ± 0.064	1.985ProPro: 1.985 ± 0.075	1.659ProGln: 1.659 ± 0.047	3.173ProArg: 3.173 ± 0.079	2.972ProSer: 2.972 ± 0.068	3.595ProThr: 3.595 ± 0.072	4.624ProVal: 4.624 ± 0.097	0.731ProTrp: 0.731 ± 0.036	1.031ProTyr: 1.031 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.748GlnAla: 3.748 ± 0.078	0.153GlnCys: 0.153 ± 0.013	1.406GlnAsp: 1.406 ± 0.045	1.523GlnGlu: 1.523 ± 0.051	0.884GlnPhe: 0.884 ± 0.036	2.04GlnGly: 2.04 ± 0.051	0.683GlnHis: 0.683 ± 0.029	1.345GlnIle: 1.345 ± 0.048	0.708GlnLys: 0.708 ± 0.035	3.615GlnLeu: 3.615 ± 0.079	0.657GlnMet: 0.657 ± 0.033	0.582GlnAsn: 0.582 ± 0.031	1.808GlnPro: 1.808 ± 0.056	1.364GlnGln: 1.364 ± 0.048	2.799GlnArg: 2.799 ± 0.064	1.363GlnSer: 1.363 ± 0.044	1.363GlnThr: 1.363 ± 0.048	2.473GlnVal: 2.473 ± 0.064	0.578GlnTrp: 0.578 ± 0.029	0.592GlnTyr: 0.592 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	7.402ArgAla: 7.402 ± 0.134	0.472ArgCys: 0.472 ± 0.029	3.886ArgAsp: 3.886 ± 0.086	4.074ArgGlu: 4.074 ± 0.091	2.198ArgPhe: 2.198 ± 0.052	4.998ArgGly: 4.998 ± 0.098	1.601ArgHis: 1.601 ± 0.046	3.388ArgIle: 3.388 ± 0.07	1.741ArgLys: 1.741 ± 0.053	6.677ArgLeu: 6.677 ± 0.129	1.656ArgMet: 1.656 ± 0.047	1.56ArgAsn: 1.56 ± 0.046	3.386ArgPro: 3.386 ± 0.081	2.174ArgGln: 2.174 ± 0.056	6.429ArgArg: 6.429 ± 0.153	3.635ArgSer: 3.635 ± 0.081	3.702ArgThr: 3.702 ± 0.082	5.231ArgVal: 5.231 ± 0.099	1.016ArgTrp: 1.016 ± 0.044	1.681ArgTyr: 1.681 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.988SerAla: 6.988 ± 0.108	0.372SerCys: 0.372 ± 0.025	3.011SerAsp: 3.011 ± 0.063	2.94SerGlu: 2.94 ± 0.06	2.043SerPhe: 2.043 ± 0.053	5.279SerGly: 5.279 ± 0.082	1.197SerHis: 1.197 ± 0.044	2.415SerIle: 2.415 ± 0.066	1.322SerLys: 1.322 ± 0.047	5.448SerLeu: 5.448 ± 0.088	1.445SerMet: 1.445 ± 0.048	1.314SerAsn: 1.314 ± 0.041	3.024SerPro: 3.024 ± 0.067	1.786SerGln: 1.786 ± 0.059	3.706SerArg: 3.706 ± 0.072	3.634SerSer: 3.634 ± 0.093	3.88SerThr: 3.88 ± 0.069	4.672SerVal: 4.672 ± 0.081	0.874SerTrp: 0.874 ± 0.037	1.417SerTyr: 1.417 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	7.368ThrAla: 7.368 ± 0.118	0.457ThrCys: 0.457 ± 0.026	3.478ThrAsp: 3.478 ± 0.076	3.279ThrGlu: 3.279 ± 0.072	1.904ThrPhe: 1.904 ± 0.056	5.36ThrGly: 5.36 ± 0.083	1.345ThrHis: 1.345 ± 0.047	3.073ThrIle: 3.073 ± 0.071	1.507ThrLys: 1.507 ± 0.053	5.917ThrLeu: 5.917 ± 0.097	1.225ThrMet: 1.225 ± 0.044	1.514ThrAsn: 1.514 ± 0.053	4.003ThrPro: 4.003 ± 0.085	1.662ThrGln: 1.662 ± 0.043	3.744ThrArg: 3.744 ± 0.077	3.609ThrSer: 3.609 ± 0.079	4.263ThrThr: 4.263 ± 0.088	5.81ThrVal: 5.81 ± 0.099	0.909ThrTrp: 0.909 ± 0.037	1.432ThrTyr: 1.432 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	11.491ValAla: 11.491 ± 0.169	0.669ValCys: 0.669 ± 0.031	6.171ValAsp: 6.171 ± 0.103	5.147ValGlu: 5.147 ± 0.089	2.681ValPhe: 2.681 ± 0.073	7.104ValGly: 7.104 ± 0.123	1.652ValHis: 1.652 ± 0.052	4.334ValIle: 4.334 ± 0.095	1.837ValLys: 1.837 ± 0.053	8.365ValLeu: 8.365 ± 0.118	1.699ValMet: 1.699 ± 0.052	2.089ValAsn: 2.089 ± 0.042	4.177ValPro: 4.177 ± 0.085	1.773ValGln: 1.773 ± 0.052	5.155ValArg: 5.155 ± 0.106	5.091ValSer: 5.091 ± 0.09	5.989ValThr: 5.989 ± 0.092	8.621ValVal: 8.621 ± 0.163	1.055ValTrp: 1.055 ± 0.042	1.687ValTyr: 1.687 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	1.583TrpAla: 1.583 ± 0.055	0.106TrpCys: 0.106 ± 0.014	0.639TrpAsp: 0.639 ± 0.028	0.681TrpGlu: 0.681 ± 0.032	0.512TrpPhe: 0.512 ± 0.035	0.926TrpGly: 0.926 ± 0.035	0.338TrpHis: 0.338 ± 0.022	0.603TrpIle: 0.603 ± 0.027	0.306TrpLys: 0.306 ± 0.02	1.706TrpLeu: 1.706 ± 0.051	0.298TrpMet: 0.298 ± 0.021	0.386TrpAsn: 0.386 ± 0.026	0.644TrpPro: 0.644 ± 0.032	0.562TrpGln: 0.562 ± 0.028	1.016TrpArg: 1.016 ± 0.042	0.742TrpSer: 0.742 ± 0.033	0.736TrpThr: 0.736 ± 0.03	1.139TrpVal: 1.139 ± 0.047	0.328TrpTrp: 0.328 ± 0.025	0.296TrpTyr: 0.296 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.483TyrAla: 2.483 ± 0.062	0.193TyrCys: 0.193 ± 0.015	1.453TyrAsp: 1.453 ± 0.049	1.25TyrGlu: 1.25 ± 0.045	0.831TyrPhe: 0.831 ± 0.037	2.071TyrGly: 2.071 ± 0.052	0.53TyrHis: 0.53 ± 0.028	0.796TyrIle: 0.796 ± 0.035	0.429TyrLys: 0.429 ± 0.024	2.487TyrLeu: 2.487 ± 0.066	0.31TyrMet: 0.31 ± 0.021	0.582TyrAsn: 0.582 ± 0.032	1.232TyrPro: 1.232 ± 0.035	0.841TyrGln: 0.841 ± 0.034	1.755TyrArg: 1.755 ± 0.057	1.424TyrSer: 1.424 ± 0.045	1.308TyrThr: 1.308 ± 0.047	1.74TyrVal: 1.74 ± 0.045	0.323TyrTrp: 0.323 ± 0.025	0.568TyrTyr: 0.568 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2149 proteins (718476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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