Amino acid dipepetide frequency for Human associated gemykibivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.208AlaAla: 1.208 ± 0.916
0.0AlaCys: 0.0 ± 0.0
1.208AlaAsp: 1.208 ± 0.88
3.623AlaGlu: 3.623 ± 1.51
4.831AlaPhe: 4.831 ± 0.652
4.831AlaGly: 4.831 ± 0.652
1.208AlaHis: 1.208 ± 0.916
4.831AlaIle: 4.831 ± 2.422
1.208AlaLys: 1.208 ± 0.916
2.415AlaLeu: 2.415 ± 1.177
0.0AlaMet: 0.0 ± 0.0
2.415AlaAsn: 2.415 ± 1.177
4.831AlaPro: 4.831 ± 1.783
2.415AlaGln: 2.415 ± 1.759
8.454AlaArg: 8.454 ± 1.215
4.831AlaSer: 4.831 ± 4.158
2.415AlaThr: 2.415 ± 0.891
2.415AlaVal: 2.415 ± 1.759
1.208AlaTrp: 1.208 ± 0.916
2.415AlaTyr: 2.415 ± 1.831
0.0AlaXaa: 0.0 ± 0.0
Cys
1.208CysAla: 1.208 ± 1.472
0.0CysCys: 0.0 ± 0.0
1.208CysAsp: 1.208 ± 0.916
1.208CysGlu: 1.208 ± 0.916
0.0CysPhe: 0.0 ± 0.0
1.208CysGly: 1.208 ± 1.472
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.415CysLeu: 2.415 ± 0.891
0.0CysMet: 0.0 ± 0.0
1.208CysAsn: 1.208 ± 0.916
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.415CysArg: 2.415 ± 0.891
3.623CysSer: 3.623 ± 2.503
1.208CysThr: 1.208 ± 1.472
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.415AspAla: 2.415 ± 0.891
0.0AspCys: 0.0 ± 0.0
3.623AspAsp: 3.623 ± 1.516
4.831AspGlu: 4.831 ± 2.422
4.831AspPhe: 4.831 ± 3.663
3.623AspGly: 3.623 ± 2.747
0.0AspHis: 0.0 ± 0.0
2.415AspIle: 2.415 ± 1.759
2.415AspLys: 2.415 ± 0.891
4.831AspLeu: 4.831 ± 0.926
1.208AspMet: 1.208 ± 0.88
2.415AspAsn: 2.415 ± 0.891
1.208AspPro: 1.208 ± 0.916
2.415AspGln: 2.415 ± 1.759
1.208AspArg: 1.208 ± 0.88
4.831AspSer: 4.831 ± 2.058
6.039AspThr: 6.039 ± 2.326
6.039AspVal: 6.039 ± 2.326
1.208AspTrp: 1.208 ± 0.88
1.208AspTyr: 1.208 ± 0.916
0.0AspXaa: 0.0 ± 0.0
Glu
1.208GluAla: 1.208 ± 1.472
2.415GluCys: 2.415 ± 1.177
3.623GluAsp: 3.623 ± 1.516
3.623GluGlu: 3.623 ± 1.809
1.208GluPhe: 1.208 ± 0.916
4.831GluGly: 4.831 ± 1.783
1.208GluHis: 1.208 ± 1.472
1.208GluIle: 1.208 ± 0.916
1.208GluLys: 1.208 ± 0.88
7.246GluLeu: 7.246 ± 2.369
0.0GluMet: 0.0 ± 0.0
1.208GluAsn: 1.208 ± 0.916
2.415GluPro: 2.415 ± 1.177
0.0GluGln: 0.0 ± 0.0
4.831GluArg: 4.831 ± 2.422
7.246GluSer: 7.246 ± 1.179
4.831GluThr: 4.831 ± 2.354
2.415GluVal: 2.415 ± 2.944
2.415GluTrp: 2.415 ± 1.177
1.208GluTyr: 1.208 ± 0.916
0.0GluXaa: 0.0 ± 0.0
Phe
1.208PheAla: 1.208 ± 0.88
0.0PheCys: 0.0 ± 0.0
6.039PheAsp: 6.039 ± 3.304
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
4.831PheGly: 4.831 ± 2.203
1.208PheHis: 1.208 ± 0.916
1.208PheIle: 1.208 ± 1.472
1.208PheLys: 1.208 ± 0.916
1.208PheLeu: 1.208 ± 0.916
3.623PheMet: 3.623 ± 2.639
0.0PheAsn: 0.0 ± 0.0
1.208PhePro: 1.208 ± 0.916
1.208PheGln: 1.208 ± 1.472
2.415PheArg: 2.415 ± 1.759
6.039PheSer: 6.039 ± 3.154
2.415PheThr: 2.415 ± 0.891
3.623PheVal: 3.623 ± 1.579
3.623PheTrp: 3.623 ± 1.579
2.415PheTyr: 2.415 ± 0.891
0.0PheXaa: 0.0 ± 0.0
Gly
4.831GlyAla: 4.831 ± 2.058
3.623GlyCys: 3.623 ± 2.73
6.039GlyAsp: 6.039 ± 1.707
0.0GlyGlu: 0.0 ± 0.0
2.415GlyPhe: 2.415 ± 1.831
10.87GlyGly: 10.87 ± 4.122
1.208GlyHis: 1.208 ± 0.916
1.208GlyIle: 1.208 ± 0.916
2.415GlyLys: 2.415 ± 1.831
7.246GlyLeu: 7.246 ± 1.682
0.0GlyMet: 0.0 ± 0.0
4.831GlyAsn: 4.831 ± 0.926
4.831GlyPro: 4.831 ± 0.926
1.208GlyGln: 1.208 ± 0.88
4.831GlyArg: 4.831 ± 0.926
3.623GlySer: 3.623 ± 0.59
3.623GlyThr: 3.623 ± 1.579
7.246GlyVal: 7.246 ± 3.157
1.208GlyTrp: 1.208 ± 1.472
2.415GlyTyr: 2.415 ± 1.395
0.0GlyXaa: 0.0 ± 0.0
His
3.623HisAla: 3.623 ± 1.51
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.208HisGlu: 1.208 ± 0.88
0.0HisPhe: 0.0 ± 0.0
1.208HisGly: 1.208 ± 0.916
1.208HisHis: 1.208 ± 1.472
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.415HisLeu: 2.415 ± 1.177
0.0HisMet: 0.0 ± 0.0
1.208HisAsn: 1.208 ± 0.916
2.415HisPro: 2.415 ± 0.891
2.415HisGln: 2.415 ± 1.177
0.0HisArg: 0.0 ± 0.0
1.208HisSer: 1.208 ± 1.472
0.0HisThr: 0.0 ± 0.0
2.415HisVal: 2.415 ± 2.944
3.623HisTrp: 3.623 ± 2.503
2.415HisTyr: 2.415 ± 1.177
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.208IleCys: 1.208 ± 1.472
3.623IleAsp: 3.623 ± 1.579
0.0IleGlu: 0.0 ± 0.0
2.415IlePhe: 2.415 ± 0.891
2.415IleGly: 2.415 ± 1.395
1.208IleHis: 1.208 ± 0.916
2.415IleIle: 2.415 ± 1.831
2.415IleLys: 2.415 ± 1.831
4.831IleLeu: 4.831 ± 0.652
3.623IleMet: 3.623 ± 2.342
1.208IleAsn: 1.208 ± 0.916
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
3.623IleArg: 3.623 ± 1.516
1.208IleSer: 1.208 ± 0.88
4.831IleThr: 4.831 ± 0.926
3.623IleVal: 3.623 ± 1.516
2.415IleTrp: 2.415 ± 1.831
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.208LysAla: 1.208 ± 0.88
0.0LysCys: 0.0 ± 0.0
3.623LysAsp: 3.623 ± 1.51
1.208LysGlu: 1.208 ± 0.88
3.623LysPhe: 3.623 ± 2.747
1.208LysGly: 1.208 ± 0.88
1.208LysHis: 1.208 ± 0.916
1.208LysIle: 1.208 ± 1.472
1.208LysLys: 1.208 ± 0.88
2.415LysLeu: 2.415 ± 2.944
3.623LysMet: 3.623 ± 2.73
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
1.208LysGln: 1.208 ± 0.916
1.208LysArg: 1.208 ± 0.916
2.415LysSer: 2.415 ± 1.831
1.208LysThr: 1.208 ± 0.916
2.415LysVal: 2.415 ± 1.759
0.0LysTrp: 0.0 ± 0.0
4.831LysTyr: 4.831 ± 1.783
0.0LysXaa: 0.0 ± 0.0
Leu
1.208LeuAla: 1.208 ± 0.916
3.623LeuCys: 3.623 ± 1.579
4.831LeuAsp: 4.831 ± 2.422
7.246LeuGlu: 7.246 ± 3.048
4.831LeuPhe: 4.831 ± 1.783
8.454LeuGly: 8.454 ± 2.154
3.623LeuHis: 3.623 ± 1.51
1.208LeuIle: 1.208 ± 1.472
2.415LeuLys: 2.415 ± 1.395
8.454LeuLeu: 8.454 ± 2.645
0.0LeuMet: 0.0 ± 0.0
4.831LeuAsn: 4.831 ± 0.652
3.623LeuPro: 3.623 ± 0.59
4.831LeuGln: 4.831 ± 2.058
9.662LeuArg: 9.662 ± 2.167
4.831LeuSer: 4.831 ± 2.354
2.415LeuThr: 2.415 ± 1.395
6.039LeuVal: 6.039 ± 2.548
0.0LeuTrp: 0.0 ± 0.0
1.208LeuTyr: 1.208 ± 0.88
0.0LeuXaa: 0.0 ± 0.0
Met
1.208MetAla: 1.208 ± 0.88
1.208MetCys: 1.208 ± 0.916
2.415MetAsp: 2.415 ± 1.759
1.208MetGlu: 1.208 ± 1.472
0.0MetPhe: 0.0 ± 0.0
4.831MetGly: 4.831 ± 0.652
1.208MetHis: 1.208 ± 1.472
0.0MetIle: 0.0 ± 0.0
1.208MetLys: 1.208 ± 1.472
3.623MetLeu: 3.623 ± 1.809
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
3.623MetGln: 3.623 ± 4.416
1.208MetArg: 1.208 ± 0.88
2.415MetSer: 2.415 ± 1.395
1.208MetThr: 1.208 ± 0.88
0.0MetVal: 0.0 ± 0.0
1.208MetTrp: 1.208 ± 0.88
2.415MetTyr: 2.415 ± 1.395
0.0MetXaa: 0.0 ± 0.0
Asn
7.246AsnAla: 7.246 ± 3.157
1.208AsnCys: 1.208 ± 0.916
2.415AsnAsp: 2.415 ± 1.395
1.208AsnGlu: 1.208 ± 0.916
1.208AsnPhe: 1.208 ± 1.472
0.0AsnGly: 0.0 ± 0.0
2.415AsnHis: 2.415 ± 1.177
3.623AsnIle: 3.623 ± 1.51
1.208AsnLys: 1.208 ± 1.472
2.415AsnLeu: 2.415 ± 0.891
1.208AsnMet: 1.208 ± 0.88
1.208AsnAsn: 1.208 ± 0.916
1.208AsnPro: 1.208 ± 0.88
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
6.039AsnSer: 6.039 ± 1.937
0.0AsnThr: 0.0 ± 0.0
4.831AsnVal: 4.831 ± 1.783
1.208AsnTrp: 1.208 ± 0.916
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.831ProAla: 4.831 ± 1.783
2.415ProCys: 2.415 ± 1.177
1.208ProAsp: 1.208 ± 0.88
6.039ProGlu: 6.039 ± 1.477
2.415ProPhe: 2.415 ± 1.759
2.415ProGly: 2.415 ± 1.395
0.0ProHis: 0.0 ± 0.0
7.246ProIle: 7.246 ± 3.032
0.0ProLys: 0.0 ± 0.0
2.415ProLeu: 2.415 ± 1.759
1.208ProMet: 1.208 ± 0.88
3.623ProAsn: 3.623 ± 0.59
0.0ProPro: 0.0 ± 0.0
1.208ProGln: 1.208 ± 0.88
4.831ProArg: 4.831 ± 2.203
6.039ProSer: 6.039 ± 3.304
1.208ProThr: 1.208 ± 1.472
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.208ProTyr: 1.208 ± 0.916
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.623GlnGlu: 3.623 ± 1.809
2.415GlnPhe: 2.415 ± 0.891
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.208GlnIle: 1.208 ± 1.472
3.623GlnLys: 3.623 ± 0.59
3.623GlnLeu: 3.623 ± 0.59
1.208GlnMet: 1.208 ± 0.916
1.208GlnAsn: 1.208 ± 0.916
0.0GlnPro: 0.0 ± 0.0
2.415GlnGln: 2.415 ± 1.177
1.208GlnArg: 1.208 ± 1.472
3.623GlnSer: 3.623 ± 4.416
2.415GlnThr: 2.415 ± 1.759
0.0GlnVal: 0.0 ± 0.0
1.208GlnTrp: 1.208 ± 0.916
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.039ArgAla: 6.039 ± 1.477
0.0ArgCys: 0.0 ± 0.0
3.623ArgAsp: 3.623 ± 1.579
3.623ArgGlu: 3.623 ± 2.503
4.831ArgPhe: 4.831 ± 3.518
6.039ArgGly: 6.039 ± 2.326
1.208ArgHis: 1.208 ± 1.472
3.623ArgIle: 3.623 ± 1.516
3.623ArgLys: 3.623 ± 1.516
7.246ArgLeu: 7.246 ± 1.179
4.831ArgMet: 4.831 ± 3.645
2.415ArgAsn: 2.415 ± 0.891
7.246ArgPro: 7.246 ± 1.165
0.0ArgGln: 0.0 ± 0.0
25.362ArgArg: 25.362 ± 12.264
10.87ArgSer: 10.87 ± 1.769
4.831ArgThr: 4.831 ± 2.313
6.039ArgVal: 6.039 ± 3.154
1.208ArgTrp: 1.208 ± 1.472
3.623ArgTyr: 3.623 ± 2.503
0.0ArgXaa: 0.0 ± 0.0
Ser
4.831SerAla: 4.831 ± 2.354
0.0SerCys: 0.0 ± 0.0
3.623SerAsp: 3.623 ± 1.516
4.831SerGlu: 4.831 ± 2.354
3.623SerPhe: 3.623 ± 0.59
3.623SerGly: 3.623 ± 2.73
1.208SerHis: 1.208 ± 1.472
4.831SerIle: 4.831 ± 2.203
1.208SerLys: 1.208 ± 1.472
8.454SerLeu: 8.454 ± 4.757
3.623SerMet: 3.623 ± 2.652
4.831SerAsn: 4.831 ± 2.058
9.662SerPro: 9.662 ± 0.37
1.208SerGln: 1.208 ± 1.472
13.285SerArg: 13.285 ± 3.073
6.039SerSer: 6.039 ± 1.707
6.039SerThr: 6.039 ± 4.078
3.623SerVal: 3.623 ± 2.639
1.208SerTrp: 1.208 ± 0.916
3.623SerTyr: 3.623 ± 1.516
0.0SerXaa: 0.0 ± 0.0
Thr
3.623ThrAla: 3.623 ± 2.639
0.0ThrCys: 0.0 ± 0.0
1.208ThrAsp: 1.208 ± 0.916
3.623ThrGlu: 3.623 ± 1.579
1.208ThrPhe: 1.208 ± 0.88
3.623ThrGly: 3.623 ± 0.59
0.0ThrHis: 0.0 ± 0.0
2.415ThrIle: 2.415 ± 0.891
0.0ThrLys: 0.0 ± 0.0
4.831ThrLeu: 4.831 ± 5.888
0.0ThrMet: 0.0 ± 0.0
3.623ThrAsn: 3.623 ± 2.639
6.039ThrPro: 6.039 ± 2.395
2.415ThrGln: 2.415 ± 1.831
9.662ThrArg: 9.662 ± 3.403
8.454ThrSer: 8.454 ± 0.842
1.208ThrThr: 1.208 ± 0.88
2.415ThrVal: 2.415 ± 1.759
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.415ValAla: 2.415 ± 0.891
0.0ValCys: 0.0 ± 0.0
7.246ValAsp: 7.246 ± 2.674
4.831ValGlu: 4.831 ± 2.203
2.415ValPhe: 2.415 ± 1.759
7.246ValGly: 7.246 ± 4.067
3.623ValHis: 3.623 ± 2.503
2.415ValIle: 2.415 ± 1.759
3.623ValLys: 3.623 ± 0.59
0.0ValLeu: 0.0 ± 0.0
2.415ValMet: 2.415 ± 1.759
1.208ValAsn: 1.208 ± 0.916
2.415ValPro: 2.415 ± 1.759
1.208ValGln: 1.208 ± 0.916
4.831ValArg: 4.831 ± 2.48
2.415ValSer: 2.415 ± 1.831
7.246ValThr: 7.246 ± 3.032
7.246ValVal: 7.246 ± 2.674
1.208ValTrp: 1.208 ± 0.916
2.415ValTyr: 2.415 ± 1.831
0.0ValXaa: 0.0 ± 0.0
Trp
3.623TrpAla: 3.623 ± 1.579
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.208TrpGly: 1.208 ± 1.472
2.415TrpHis: 2.415 ± 1.759
0.0TrpIle: 0.0 ± 0.0
1.208TrpLys: 1.208 ± 0.916
6.039TrpLeu: 6.039 ± 2.548
1.208TrpMet: 1.208 ± 1.472
0.0TrpAsn: 0.0 ± 0.0
1.208TrpPro: 1.208 ± 0.916
0.0TrpGln: 0.0 ± 0.0
1.208TrpArg: 1.208 ± 0.88
3.623TrpSer: 3.623 ± 1.51
0.0TrpThr: 0.0 ± 0.0
2.415TrpVal: 2.415 ± 1.831
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.831TyrAla: 4.831 ± 2.203
0.0TyrCys: 0.0 ± 0.0
1.208TyrAsp: 1.208 ± 0.88
2.415TyrGlu: 2.415 ± 0.891
1.208TyrPhe: 1.208 ± 0.916
1.208TyrGly: 1.208 ± 0.916
1.208TyrHis: 1.208 ± 1.472
0.0TyrIle: 0.0 ± 0.0
3.623TyrLys: 3.623 ± 1.579
1.208TyrLeu: 1.208 ± 0.916
0.0TyrMet: 0.0 ± 0.0
1.208TyrAsn: 1.208 ± 1.472
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
7.246TyrArg: 7.246 ± 1.179
0.0TyrSer: 0.0 ± 0.0
1.208TyrThr: 1.208 ± 0.916
3.623TyrVal: 3.623 ± 1.516
1.208TyrTrp: 1.208 ± 0.88
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (829 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski