Amino acid dipepetide frequency for Torque teno virus (isolate Chimpanzee/Japan/Pt-TTV6/2000) (TTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.901AlaAla: 7.901 ± 11.502
1.129AlaCys: 1.129 ± 0.517
5.643AlaAsp: 5.643 ± 0.439
2.257AlaGlu: 2.257 ± 1.99
2.257AlaPhe: 2.257 ± 1.99
5.643AlaGly: 5.643 ± 6.488
0.0AlaHis: 0.0 ± 0.0
3.386AlaIle: 3.386 ± 1.551
0.0AlaLys: 0.0 ± 0.0
3.386AlaLeu: 3.386 ± 7.522
1.129AlaMet: 1.129 ± 0.485
3.386AlaAsn: 3.386 ± 1.473
7.901AlaPro: 7.901 ± 8.478
1.129AlaGln: 1.129 ± 0.517
1.129AlaArg: 1.129 ± 0.517
4.515AlaSer: 4.515 ± 2.069
2.257AlaThr: 2.257 ± 1.034
4.515AlaVal: 4.515 ± 0.956
1.129AlaTrp: 1.129 ± 0.517
2.257AlaTyr: 2.257 ± 1.034
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
3.386CysAsp: 3.386 ± 1.551
0.0CysGlu: 0.0 ± 0.0
1.129CysPhe: 1.129 ± 0.517
3.386CysGly: 3.386 ± 4.497
0.0CysHis: 0.0 ± 0.0
1.129CysIle: 1.129 ± 0.517
1.129CysLys: 1.129 ± 0.517
1.129CysLeu: 1.129 ± 2.507
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.129CysPro: 1.129 ± 2.507
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.129CysThr: 1.129 ± 0.517
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.386AspAla: 3.386 ± 4.497
0.0AspCys: 0.0 ± 0.0
1.129AspAsp: 1.129 ± 0.517
4.515AspGlu: 4.515 ± 3.98
3.386AspPhe: 3.386 ± 1.473
4.515AspGly: 4.515 ± 3.98
1.129AspHis: 1.129 ± 0.517
4.515AspIle: 4.515 ± 2.069
2.257AspLys: 2.257 ± 1.034
4.515AspLeu: 4.515 ± 0.956
1.129AspMet: 1.129 ± 0.517
0.0AspAsn: 0.0 ± 0.0
3.386AspPro: 3.386 ± 1.551
1.129AspGln: 1.129 ± 0.517
2.257AspArg: 2.257 ± 1.99
2.257AspSer: 2.257 ± 1.034
2.257AspThr: 2.257 ± 1.034
1.129AspVal: 1.129 ± 0.517
0.0AspTrp: 0.0 ± 0.0
1.129AspTyr: 1.129 ± 0.517
0.0AspXaa: 0.0 ± 0.0
Glu
3.386GluAla: 3.386 ± 1.551
0.0GluCys: 0.0 ± 0.0
4.515GluAsp: 4.515 ± 3.98
2.257GluGlu: 2.257 ± 1.034
1.129GluPhe: 1.129 ± 0.517
1.129GluGly: 1.129 ± 0.517
0.0GluHis: 0.0 ± 0.0
3.386GluIle: 3.386 ± 1.551
2.257GluLys: 2.257 ± 1.034
2.257GluLeu: 2.257 ± 1.034
0.0GluMet: 0.0 ± 1.331
3.386GluAsn: 3.386 ± 1.551
1.129GluPro: 1.129 ± 2.507
4.515GluGln: 4.515 ± 2.069
1.129GluArg: 1.129 ± 2.507
3.386GluSer: 3.386 ± 1.473
1.129GluThr: 1.129 ± 0.517
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.129GluTyr: 1.129 ± 0.517
0.0GluXaa: 0.0 ± 0.0
Phe
1.129PheAla: 1.129 ± 2.507
1.129PheCys: 1.129 ± 2.507
0.0PheAsp: 0.0 ± 0.0
2.257PheGlu: 2.257 ± 1.034
1.129PhePhe: 1.129 ± 0.517
5.643PheGly: 5.643 ± 2.586
2.257PheHis: 2.257 ± 1.034
4.515PheIle: 4.515 ± 2.069
2.257PheLys: 2.257 ± 1.034
3.386PheLeu: 3.386 ± 1.551
0.0PheMet: 0.0 ± 0.0
1.129PheAsn: 1.129 ± 0.517
1.129PhePro: 1.129 ± 2.507
2.257PheGln: 2.257 ± 1.034
0.0PheArg: 0.0 ± 0.0
2.257PheSer: 2.257 ± 1.99
3.386PheThr: 3.386 ± 1.551
3.386PheVal: 3.386 ± 1.473
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.772GlyAla: 6.772 ± 8.995
1.129GlyCys: 1.129 ± 2.507
5.643GlyAsp: 5.643 ± 9.512
1.129GlyGlu: 1.129 ± 0.517
3.386GlyPhe: 3.386 ± 1.551
11.287GlyGly: 11.287 ± 6.926
0.0GlyHis: 0.0 ± 0.0
1.129GlyIle: 1.129 ± 0.517
4.515GlyLys: 4.515 ± 0.956
5.643GlyLeu: 5.643 ± 0.439
3.386GlyMet: 3.386 ± 1.551
3.386GlyAsn: 3.386 ± 1.551
5.643GlyPro: 5.643 ± 0.439
0.0GlyGln: 0.0 ± 0.0
6.772GlyArg: 6.772 ± 2.946
3.386GlySer: 3.386 ± 1.551
3.386GlyThr: 3.386 ± 1.473
0.0GlyVal: 0.0 ± 0.0
3.386GlyTrp: 3.386 ± 1.473
3.386GlyTyr: 3.386 ± 1.551
0.0GlyXaa: 0.0 ± 0.0
His
3.386HisAla: 3.386 ± 1.473
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.129HisPhe: 1.129 ± 2.507
1.129HisGly: 1.129 ± 0.517
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.257HisLys: 2.257 ± 1.034
3.386HisLeu: 3.386 ± 1.473
1.129HisMet: 1.129 ± 0.517
2.257HisAsn: 2.257 ± 1.99
3.386HisPro: 3.386 ± 1.551
2.257HisGln: 2.257 ± 1.034
2.257HisArg: 2.257 ± 1.99
1.129HisSer: 1.129 ± 0.517
2.257HisThr: 2.257 ± 1.034
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.129HisTyr: 1.129 ± 0.517
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
2.257IleCys: 2.257 ± 1.034
1.129IleAsp: 1.129 ± 0.517
1.129IleGlu: 1.129 ± 0.517
0.0IlePhe: 0.0 ± 0.0
3.386IleGly: 3.386 ± 1.551
1.129IleHis: 1.129 ± 0.517
4.515IleIle: 4.515 ± 2.069
4.515IleLys: 4.515 ± 2.069
3.386IleLeu: 3.386 ± 1.551
0.0IleMet: 0.0 ± 0.0
1.129IleAsn: 1.129 ± 0.517
0.0IlePro: 0.0 ± 0.0
1.129IleGln: 1.129 ± 0.517
2.257IleArg: 2.257 ± 1.034
4.515IleSer: 4.515 ± 2.069
4.515IleThr: 4.515 ± 2.069
1.129IleVal: 1.129 ± 0.517
2.257IleTrp: 2.257 ± 1.034
2.257IleTyr: 2.257 ± 1.034
0.0IleXaa: 0.0 ± 0.0
Lys
3.386LysAla: 3.386 ± 1.551
0.0LysCys: 0.0 ± 0.0
2.257LysAsp: 2.257 ± 1.034
1.129LysGlu: 1.129 ± 0.517
2.257LysPhe: 2.257 ± 1.034
7.901LysGly: 7.901 ± 0.596
0.0LysHis: 0.0 ± 0.0
4.515LysIle: 4.515 ± 2.069
5.643LysLys: 5.643 ± 0.439
3.386LysLeu: 3.386 ± 1.473
1.129LysMet: 1.129 ± 0.517
1.129LysAsn: 1.129 ± 0.517
2.257LysPro: 2.257 ± 1.034
1.129LysGln: 1.129 ± 0.517
2.257LysArg: 2.257 ± 1.034
2.257LysSer: 2.257 ± 1.034
2.257LysThr: 2.257 ± 1.034
2.257LysVal: 2.257 ± 1.99
1.129LysTrp: 1.129 ± 0.517
3.386LysTyr: 3.386 ± 1.551
0.0LysXaa: 0.0 ± 0.0
Leu
4.515LeuAla: 4.515 ± 0.956
0.0LeuCys: 0.0 ± 0.0
3.386LeuAsp: 3.386 ± 1.473
3.386LeuGlu: 3.386 ± 1.473
3.386LeuPhe: 3.386 ± 1.473
4.515LeuGly: 4.515 ± 0.956
1.129LeuHis: 1.129 ± 0.517
5.643LeuIle: 5.643 ± 2.586
1.129LeuLys: 1.129 ± 0.517
4.515LeuLeu: 4.515 ± 2.069
2.257LeuMet: 2.257 ± 1.034
5.643LeuAsn: 5.643 ± 0.439
7.901LeuPro: 7.901 ± 11.502
3.386LeuGln: 3.386 ± 1.551
11.287LeuArg: 11.287 ± 2.147
2.257LeuSer: 2.257 ± 1.99
11.287LeuThr: 11.287 ± 5.172
1.129LeuVal: 1.129 ± 0.517
1.129LeuTrp: 1.129 ± 0.517
4.515LeuTyr: 4.515 ± 2.069
0.0LeuXaa: 0.0 ± 0.0
Met
2.257MetAla: 2.257 ± 1.034
0.0MetCys: 0.0 ± 0.0
1.129MetAsp: 1.129 ± 0.517
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
1.129MetHis: 1.129 ± 2.507
0.0MetIle: 0.0 ± 0.0
1.129MetLys: 1.129 ± 0.517
3.386MetLeu: 3.386 ± 1.551
1.129MetMet: 1.129 ± 0.517
0.0MetAsn: 0.0 ± 0.0
2.257MetPro: 2.257 ± 1.034
1.129MetGln: 1.129 ± 0.517
1.129MetArg: 1.129 ± 0.517
3.386MetSer: 3.386 ± 1.473
1.129MetThr: 1.129 ± 0.517
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.129MetTyr: 1.129 ± 0.517
0.0MetXaa: 0.0 ± 0.0
Asn
1.129AsnAla: 1.129 ± 0.517
0.0AsnCys: 0.0 ± 0.0
1.129AsnAsp: 1.129 ± 0.517
1.129AsnGlu: 1.129 ± 0.517
1.129AsnPhe: 1.129 ± 0.517
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.129AsnIle: 1.129 ± 0.517
2.257AsnLys: 2.257 ± 1.034
5.643AsnLeu: 5.643 ± 0.439
0.0AsnMet: 0.0 ± 0.0
4.515AsnAsn: 4.515 ± 0.956
10.158AsnPro: 10.158 ± 1.63
3.386AsnGln: 3.386 ± 1.551
1.129AsnArg: 1.129 ± 2.507
3.386AsnSer: 3.386 ± 1.551
5.643AsnThr: 5.643 ± 2.586
2.257AsnVal: 2.257 ± 1.99
2.257AsnTrp: 2.257 ± 1.99
4.515AsnTyr: 4.515 ± 2.069
0.0AsnXaa: 0.0 ± 0.0
Pro
4.515ProAla: 4.515 ± 10.029
1.129ProCys: 1.129 ± 0.517
0.0ProAsp: 0.0 ± 0.0
5.643ProGlu: 5.643 ± 0.439
5.643ProPhe: 5.643 ± 2.586
9.029ProGly: 9.029 ± 14.01
1.129ProHis: 1.129 ± 2.507
0.0ProIle: 0.0 ± 0.0
4.515ProLys: 4.515 ± 2.069
9.029ProLeu: 9.029 ± 4.936
2.257ProMet: 2.257 ± 1.034
5.643ProAsn: 5.643 ± 0.439
12.415ProPro: 12.415 ± 15.483
2.257ProGln: 2.257 ± 1.99
7.901ProArg: 7.901 ± 2.429
2.257ProSer: 2.257 ± 1.034
4.515ProThr: 4.515 ± 0.956
3.386ProVal: 3.386 ± 1.473
2.257ProTrp: 2.257 ± 1.034
4.515ProTyr: 4.515 ± 2.069
0.0ProXaa: 0.0 ± 0.0
Gln
1.129GlnAla: 1.129 ± 0.517
0.0GlnCys: 0.0 ± 0.0
3.386GlnAsp: 3.386 ± 1.551
3.386GlnGlu: 3.386 ± 1.551
3.386GlnPhe: 3.386 ± 1.551
1.129GlnGly: 1.129 ± 0.517
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.129GlnLys: 1.129 ± 0.517
4.515GlnLeu: 4.515 ± 2.069
0.0GlnMet: 0.0 ± 0.0
1.129GlnAsn: 1.129 ± 0.517
4.515GlnPro: 4.515 ± 0.956
9.029GlnGln: 9.029 ± 4.137
0.0GlnArg: 0.0 ± 0.0
1.129GlnSer: 1.129 ± 0.517
4.515GlnThr: 4.515 ± 2.069
6.772GlnVal: 6.772 ± 3.103
2.257GlnTrp: 2.257 ± 1.034
1.129GlnTyr: 1.129 ± 0.517
0.0GlnXaa: 0.0 ± 0.0
Arg
4.515ArgAla: 4.515 ± 0.956
1.129ArgCys: 1.129 ± 0.517
1.129ArgAsp: 1.129 ± 2.507
0.0ArgGlu: 0.0 ± 0.0
3.386ArgPhe: 3.386 ± 1.473
4.515ArgGly: 4.515 ± 2.069
3.386ArgHis: 3.386 ± 1.551
3.386ArgIle: 3.386 ± 1.551
3.386ArgLys: 3.386 ± 1.473
4.515ArgLeu: 4.515 ± 0.956
2.257ArgMet: 2.257 ± 1.99
5.643ArgAsn: 5.643 ± 0.439
7.901ArgPro: 7.901 ± 5.453
1.129ArgGln: 1.129 ± 0.517
32.731ArgArg: 32.731 ± 11.973
5.643ArgSer: 5.643 ± 0.439
3.386ArgThr: 3.386 ± 1.551
3.386ArgVal: 3.386 ± 1.551
4.515ArgTrp: 4.515 ± 2.069
3.386ArgTyr: 3.386 ± 1.551
0.0ArgXaa: 0.0 ± 0.0
Ser
7.901SerAla: 7.901 ± 3.62
1.129SerCys: 1.129 ± 2.507
2.257SerAsp: 2.257 ± 1.034
1.129SerGlu: 1.129 ± 0.517
2.257SerPhe: 2.257 ± 1.034
4.515SerGly: 4.515 ± 0.956
5.643SerHis: 5.643 ± 3.463
0.0SerIle: 0.0 ± 0.0
4.515SerLys: 4.515 ± 0.956
6.772SerLeu: 6.772 ± 3.103
0.0SerMet: 0.0 ± 0.0
2.257SerAsn: 2.257 ± 1.034
5.643SerPro: 5.643 ± 2.586
2.257SerGln: 2.257 ± 1.034
4.515SerArg: 4.515 ± 0.956
2.257SerSer: 2.257 ± 1.034
0.0SerThr: 0.0 ± 0.0
1.129SerVal: 1.129 ± 0.517
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.257ThrAla: 2.257 ± 1.99
0.0ThrCys: 0.0 ± 0.0
4.515ThrAsp: 4.515 ± 2.069
5.643ThrGlu: 5.643 ± 2.586
0.0ThrPhe: 0.0 ± 0.0
3.386ThrGly: 3.386 ± 1.551
5.643ThrHis: 5.643 ± 2.586
1.129ThrIle: 1.129 ± 0.517
3.386ThrLys: 3.386 ± 1.551
3.386ThrLeu: 3.386 ± 1.551
1.129ThrMet: 1.129 ± 0.517
1.129ThrAsn: 1.129 ± 0.517
1.129ThrPro: 1.129 ± 0.517
5.643ThrGln: 5.643 ± 2.586
2.257ThrArg: 2.257 ± 1.034
4.515ThrSer: 4.515 ± 2.069
6.772ThrThr: 6.772 ± 3.103
6.772ThrVal: 6.772 ± 3.103
4.515ThrTrp: 4.515 ± 0.956
3.386ThrTyr: 3.386 ± 1.551
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
1.129ValAsp: 1.129 ± 0.517
1.129ValGlu: 1.129 ± 0.517
0.0ValPhe: 0.0 ± 0.0
0.0ValGly: 0.0 ± 0.0
1.129ValHis: 1.129 ± 2.507
2.257ValIle: 2.257 ± 1.034
1.129ValLys: 1.129 ± 0.517
5.643ValLeu: 5.643 ± 2.586
0.0ValMet: 0.0 ± 0.0
2.257ValAsn: 2.257 ± 1.034
5.643ValPro: 5.643 ± 3.463
4.515ValGln: 4.515 ± 2.069
6.772ValArg: 6.772 ± 0.079
2.257ValSer: 2.257 ± 1.99
2.257ValThr: 2.257 ± 1.034
1.129ValVal: 1.129 ± 0.517
1.129ValTrp: 1.129 ± 0.517
1.129ValTyr: 1.129 ± 0.517
0.0ValXaa: 0.0 ± 0.0
Trp
1.129TrpAla: 1.129 ± 0.517
2.257TrpCys: 2.257 ± 1.99
1.129TrpAsp: 1.129 ± 0.517
0.0TrpGlu: 0.0 ± 0.0
1.129TrpPhe: 1.129 ± 0.517
2.257TrpGly: 2.257 ± 1.034
1.129TrpHis: 1.129 ± 0.517
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.129TrpMet: 1.129 ± 0.517
0.0TrpAsn: 0.0 ± 0.0
2.257TrpPro: 2.257 ± 1.99
1.129TrpGln: 1.129 ± 0.517
7.901TrpArg: 7.901 ± 3.62
0.0TrpSer: 0.0 ± 0.0
1.129TrpThr: 1.129 ± 0.517
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
3.386TrpTyr: 3.386 ± 1.473
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.257TyrAla: 2.257 ± 1.034
2.257TyrCys: 2.257 ± 1.034
1.129TyrAsp: 1.129 ± 0.517
1.129TyrGlu: 1.129 ± 2.507
1.129TyrPhe: 1.129 ± 0.517
0.0TyrGly: 0.0 ± 0.0
2.257TyrHis: 2.257 ± 1.034
0.0TyrIle: 0.0 ± 0.0
2.257TyrLys: 2.257 ± 1.034
4.515TyrLeu: 4.515 ± 2.069
1.129TyrMet: 1.129 ± 0.517
6.772TyrAsn: 6.772 ± 3.103
2.257TyrPro: 2.257 ± 1.034
1.129TyrGln: 1.129 ± 0.517
5.643TyrArg: 5.643 ± 2.586
3.386TyrSer: 3.386 ± 1.551
3.386TyrThr: 3.386 ± 1.551
1.129TyrVal: 1.129 ± 0.517
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (887 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski