Amino acid dipepetide frequency for Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.936AlaAla: 4.936 ± 0.102
0.572AlaCys: 0.572 ± 0.03
2.782AlaAsp: 2.782 ± 0.061
4.61AlaGlu: 4.61 ± 0.083
3.032AlaPhe: 3.032 ± 0.076
4.483AlaGly: 4.483 ± 0.089
1.048AlaHis: 1.048 ± 0.039
6.191AlaIle: 6.191 ± 0.086
5.322AlaLys: 5.322 ± 0.084
7.123AlaLeu: 7.123 ± 0.099
1.791AlaMet: 1.791 ± 0.056
2.396AlaAsn: 2.396 ± 0.057
1.666AlaPro: 1.666 ± 0.051
1.745AlaGln: 1.745 ± 0.046
2.844AlaArg: 2.844 ± 0.067
3.501AlaSer: 3.501 ± 0.07
2.862AlaThr: 2.862 ± 0.063
5.303AlaVal: 5.303 ± 0.095
0.471AlaTrp: 0.471 ± 0.031
2.602AlaTyr: 2.602 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.441CysAla: 0.441 ± 0.025
0.06CysCys: 0.06 ± 0.009
0.478CysAsp: 0.478 ± 0.027
0.527CysGlu: 0.527 ± 0.029
0.287CysPhe: 0.287 ± 0.018
0.832CysGly: 0.832 ± 0.044
0.136CysHis: 0.136 ± 0.014
0.567CysIle: 0.567 ± 0.03
0.56CysLys: 0.56 ± 0.027
0.572CysLeu: 0.572 ± 0.029
0.178CysMet: 0.178 ± 0.013
0.337CysAsn: 0.337 ± 0.021
0.495CysPro: 0.495 ± 0.034
0.178CysGln: 0.178 ± 0.016
0.362CysArg: 0.362 ± 0.026
0.432CysSer: 0.432 ± 0.025
0.357CysThr: 0.357 ± 0.023
0.451CysVal: 0.451 ± 0.022
0.059CysTrp: 0.059 ± 0.008
0.295CysTyr: 0.295 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
2.753AspAla: 2.753 ± 0.062
0.356AspCys: 0.356 ± 0.019
1.88AspAsp: 1.88 ± 0.054
4.155AspGlu: 4.155 ± 0.077
2.654AspPhe: 2.654 ± 0.057
3.145AspGly: 3.145 ± 0.076
0.583AspHis: 0.583 ± 0.027
5.244AspIle: 5.244 ± 0.087
4.428AspLys: 4.428 ± 0.085
4.998AspLeu: 4.998 ± 0.095
1.33AspMet: 1.33 ± 0.042
1.931AspAsn: 1.931 ± 0.059
1.952AspPro: 1.952 ± 0.06
0.698AspGln: 0.698 ± 0.033
2.191AspArg: 2.191 ± 0.049
2.228AspSer: 2.228 ± 0.053
2.099AspThr: 2.099 ± 0.055
4.188AspVal: 4.188 ± 0.076
0.453AspTrp: 0.453 ± 0.026
2.213AspTyr: 2.213 ± 0.051
0.0AspXaa: 0.0 ± 0.0
Glu
5.273GluAla: 5.273 ± 0.091
0.455GluCys: 0.455 ± 0.026
4.197GluAsp: 4.197 ± 0.084
9.952GluGlu: 9.952 ± 0.186
2.989GluPhe: 2.989 ± 0.073
5.496GluGly: 5.496 ± 0.09
0.976GluHis: 0.976 ± 0.039
8.209GluIle: 8.209 ± 0.121
9.566GluLys: 9.566 ± 0.146
6.997GluLeu: 6.997 ± 0.113
2.158GluMet: 2.158 ± 0.053
3.964GluAsn: 3.964 ± 0.069
1.717GluPro: 1.717 ± 0.047
1.721GluGln: 1.721 ± 0.055
4.006GluArg: 4.006 ± 0.084
2.909GluSer: 2.909 ± 0.069
2.779GluThr: 2.779 ± 0.06
6.817GluVal: 6.817 ± 0.102
0.531GluTrp: 0.531 ± 0.028
3.001GluTyr: 3.001 ± 0.067
0.0GluXaa: 0.0 ± 0.0
Phe
2.89PheAla: 2.89 ± 0.07
0.391PheCys: 0.391 ± 0.023
2.461PheAsp: 2.461 ± 0.059
3.274PheGlu: 3.274 ± 0.072
2.078PhePhe: 2.078 ± 0.066
3.071PheGly: 3.071 ± 0.062
0.596PheHis: 0.596 ± 0.025
3.733PheIle: 3.733 ± 0.075
3.266PheLys: 3.266 ± 0.069
4.774PheLeu: 4.774 ± 0.107
1.159PheMet: 1.159 ± 0.038
1.899PheAsn: 1.899 ± 0.058
1.439PhePro: 1.439 ± 0.051
0.846PheGln: 0.846 ± 0.03
1.51PheArg: 1.51 ± 0.043
2.884PheSer: 2.884 ± 0.069
2.215PheThr: 2.215 ± 0.056
3.271PheVal: 3.271 ± 0.073
0.348PheTrp: 0.348 ± 0.023
1.906PheTyr: 1.906 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
4.407GlyAla: 4.407 ± 0.095
0.722GlyCys: 0.722 ± 0.036
3.36GlyAsp: 3.36 ± 0.072
4.963GlyGlu: 4.963 ± 0.093
3.19GlyPhe: 3.19 ± 0.072
4.767GlyGly: 4.767 ± 0.101
1.161GlyHis: 1.161 ± 0.043
7.134GlyIle: 7.134 ± 0.108
5.962GlyLys: 5.962 ± 0.096
6.03GlyLeu: 6.03 ± 0.091
1.95GlyMet: 1.95 ± 0.054
2.721GlyAsn: 2.721 ± 0.064
1.782GlyPro: 1.782 ± 0.058
1.497GlyGln: 1.497 ± 0.05
3.104GlyArg: 3.104 ± 0.08
3.204GlySer: 3.204 ± 0.064
3.629GlyThr: 3.629 ± 0.067
5.361GlyVal: 5.361 ± 0.1
0.619GlyTrp: 0.619 ± 0.034
3.154GlyTyr: 3.154 ± 0.069
0.0GlyXaa: 0.0 ± 0.0
His
0.838HisAla: 0.838 ± 0.035
0.144HisCys: 0.144 ± 0.014
0.6HisAsp: 0.6 ± 0.029
0.954HisGlu: 0.954 ± 0.034
0.711HisPhe: 0.711 ± 0.035
1.092HisGly: 1.092 ± 0.04
0.304HisHis: 0.304 ± 0.023
1.261HisIle: 1.261 ± 0.037
0.964HisLys: 0.964 ± 0.039
1.475HisLeu: 1.475 ± 0.042
0.325HisMet: 0.325 ± 0.02
0.576HisAsn: 0.576 ± 0.027
0.883HisPro: 0.883 ± 0.036
0.366HisGln: 0.366 ± 0.022
0.634HisArg: 0.634 ± 0.027
0.762HisSer: 0.762 ± 0.033
0.719HisThr: 0.719 ± 0.033
0.935HisVal: 0.935 ± 0.035
0.151HisTrp: 0.151 ± 0.014
0.604HisTyr: 0.604 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
6.849IleAla: 6.849 ± 0.107
0.648IleCys: 0.648 ± 0.032
5.0IleAsp: 5.0 ± 0.092
7.475IleGlu: 7.475 ± 0.111
3.975IlePhe: 3.975 ± 0.087
5.999IleGly: 5.999 ± 0.107
1.172IleHis: 1.172 ± 0.043
6.967IleIle: 6.967 ± 0.131
7.931IleLys: 7.931 ± 0.127
8.631IleLeu: 8.631 ± 0.137
1.905IleMet: 1.905 ± 0.054
3.727IleAsn: 3.727 ± 0.07
3.932IlePro: 3.932 ± 0.069
1.812IleGln: 1.812 ± 0.05
3.418IleArg: 3.418 ± 0.068
5.5IleSer: 5.5 ± 0.091
4.398IleThr: 4.398 ± 0.08
6.64IleVal: 6.64 ± 0.094
0.575IleTrp: 0.575 ± 0.03
3.052IleTyr: 3.052 ± 0.073
0.0IleXaa: 0.0 ± 0.0
Lys
5.766LysAla: 5.766 ± 0.097
0.518LysCys: 0.518 ± 0.031
4.957LysAsp: 4.957 ± 0.089
9.868LysGlu: 9.868 ± 0.156
2.881LysPhe: 2.881 ± 0.061
5.997LysGly: 5.997 ± 0.097
1.078LysHis: 1.078 ± 0.04
7.72LysIle: 7.72 ± 0.101
8.106LysLys: 8.106 ± 0.138
7.259LysLeu: 7.259 ± 0.112
2.303LysMet: 2.303 ± 0.057
4.565LysAsn: 4.565 ± 0.08
2.586LysPro: 2.586 ± 0.061
1.826LysGln: 1.826 ± 0.054
4.2LysArg: 4.2 ± 0.088
3.873LysSer: 3.873 ± 0.065
3.672LysThr: 3.672 ± 0.073
6.481LysVal: 6.481 ± 0.097
0.653LysTrp: 0.653 ± 0.034
3.529LysTyr: 3.529 ± 0.072
0.0LysXaa: 0.0 ± 0.0
Leu
6.181LeuAla: 6.181 ± 0.114
0.605LeuCys: 0.605 ± 0.03
4.483LeuAsp: 4.483 ± 0.074
7.486LeuGlu: 7.486 ± 0.121
3.978LeuPhe: 3.978 ± 0.095
6.348LeuGly: 6.348 ± 0.096
1.195LeuHis: 1.195 ± 0.04
7.978LeuIle: 7.978 ± 0.13
9.836LeuLys: 9.836 ± 0.145
9.052LeuLeu: 9.052 ± 0.147
2.417LeuMet: 2.417 ± 0.054
4.626LeuAsn: 4.626 ± 0.069
3.724LeuPro: 3.724 ± 0.08
2.409LeuGln: 2.409 ± 0.058
4.17LeuArg: 4.17 ± 0.068
6.186LeuSer: 6.186 ± 0.113
4.541LeuThr: 4.541 ± 0.074
6.104LeuVal: 6.104 ± 0.093
0.731LeuTrp: 0.731 ± 0.035
3.439LeuTyr: 3.439 ± 0.073
0.0LeuXaa: 0.0 ± 0.0
Met
2.102MetAla: 2.102 ± 0.054
0.185MetCys: 0.185 ± 0.014
1.274MetAsp: 1.274 ± 0.039
1.976MetGlu: 1.976 ± 0.053
0.89MetPhe: 0.89 ± 0.038
1.845MetGly: 1.845 ± 0.056
0.324MetHis: 0.324 ± 0.02
1.881MetIle: 1.881 ± 0.047
2.303MetLys: 2.303 ± 0.053
2.304MetLeu: 2.304 ± 0.051
0.711MetMet: 0.711 ± 0.027
1.019MetAsn: 1.019 ± 0.035
1.064MetPro: 1.064 ± 0.04
0.638MetGln: 0.638 ± 0.028
1.388MetArg: 1.388 ± 0.046
1.338MetSer: 1.338 ± 0.04
1.291MetThr: 1.291 ± 0.035
1.847MetVal: 1.847 ± 0.05
0.213MetTrp: 0.213 ± 0.018
0.844MetTyr: 0.844 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
2.631AsnAla: 2.631 ± 0.067
0.42AsnCys: 0.42 ± 0.023
1.704AsnAsp: 1.704 ± 0.048
2.742AsnGlu: 2.742 ± 0.058
2.16AsnPhe: 2.16 ± 0.06
2.787AsnGly: 2.787 ± 0.064
0.522AsnHis: 0.522 ± 0.024
4.349AsnIle: 4.349 ± 0.09
3.38AsnLys: 3.38 ± 0.06
4.744AsnLeu: 4.744 ± 0.092
1.156AsnMet: 1.156 ± 0.039
1.849AsnAsn: 1.849 ± 0.053
2.295AsnPro: 2.295 ± 0.059
0.979AsnGln: 0.979 ± 0.039
1.717AsnArg: 1.717 ± 0.044
2.253AsnSer: 2.253 ± 0.065
2.068AsnThr: 2.068 ± 0.054
3.342AsnVal: 3.342 ± 0.07
0.434AsnTrp: 0.434 ± 0.029
1.969AsnTyr: 1.969 ± 0.058
0.0AsnXaa: 0.0 ± 0.0
Pro
2.061ProAla: 2.061 ± 0.061
0.27ProCys: 0.27 ± 0.019
1.985ProAsp: 1.985 ± 0.047
3.246ProGlu: 3.246 ± 0.063
1.758ProPhe: 1.758 ± 0.053
2.356ProGly: 2.356 ± 0.059
0.703ProHis: 0.703 ± 0.033
2.665ProIle: 2.665 ± 0.061
2.321ProLys: 2.321 ± 0.059
3.469ProLeu: 3.469 ± 0.077
0.757ProMet: 0.757 ± 0.03
1.372ProAsn: 1.372 ± 0.048
1.37ProPro: 1.37 ± 0.05
1.176ProGln: 1.176 ± 0.039
1.156ProArg: 1.156 ± 0.042
2.152ProSer: 2.152 ± 0.054
1.741ProThr: 1.741 ± 0.049
3.12ProVal: 3.12 ± 0.071
0.357ProTrp: 0.357 ± 0.024
1.737ProTyr: 1.737 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
1.637GlnAla: 1.637 ± 0.049
0.134GlnCys: 0.134 ± 0.014
0.988GlnAsp: 0.988 ± 0.038
2.002GlnGlu: 2.002 ± 0.05
0.858GlnPhe: 0.858 ± 0.031
1.417GlnGly: 1.417 ± 0.045
0.337GlnHis: 0.337 ± 0.023
2.211GlnIle: 2.211 ± 0.054
2.387GlnLys: 2.387 ± 0.059
2.018GlnLeu: 2.018 ± 0.048
0.676GlnMet: 0.676 ± 0.033
1.263GlnAsn: 1.263 ± 0.041
0.727GlnPro: 0.727 ± 0.039
0.807GlnGln: 0.807 ± 0.038
1.103GlnArg: 1.103 ± 0.035
1.118GlnSer: 1.118 ± 0.042
0.968GlnThr: 0.968 ± 0.036
1.585GlnVal: 1.585 ± 0.05
0.165GlnTrp: 0.165 ± 0.015
0.956GlnTyr: 0.956 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
2.457ArgAla: 2.457 ± 0.062
0.363ArgCys: 0.363 ± 0.021
2.16ArgAsp: 2.16 ± 0.055
4.305ArgGlu: 4.305 ± 0.083
1.833ArgPhe: 1.833 ± 0.047
3.083ArgGly: 3.083 ± 0.071
0.64ArgHis: 0.64 ± 0.029
3.881ArgIle: 3.881 ± 0.07
3.684ArgLys: 3.684 ± 0.073
4.002ArgLeu: 4.002 ± 0.068
1.228ArgMet: 1.228 ± 0.044
1.896ArgAsn: 1.896 ± 0.049
1.347ArgPro: 1.347 ± 0.043
1.174ArgGln: 1.174 ± 0.038
2.286ArgArg: 2.286 ± 0.07
1.735ArgSer: 1.735 ± 0.044
1.778ArgThr: 1.778 ± 0.05
3.103ArgVal: 3.103 ± 0.072
0.394ArgTrp: 0.394 ± 0.025
1.85ArgTyr: 1.85 ± 0.052
0.0ArgXaa: 0.0 ± 0.0
Ser
3.024SerAla: 3.024 ± 0.065
0.405SerCys: 0.405 ± 0.02
2.406SerAsp: 2.406 ± 0.053
3.649SerGlu: 3.649 ± 0.074
2.876SerPhe: 2.876 ± 0.065
3.751SerGly: 3.751 ± 0.071
0.934SerHis: 0.934 ± 0.041
4.725SerIle: 4.725 ± 0.086
4.141SerLys: 4.141 ± 0.083
5.482SerLeu: 5.482 ± 0.09
1.35SerMet: 1.35 ± 0.041
2.086SerAsn: 2.086 ± 0.057
2.047SerPro: 2.047 ± 0.051
1.569SerGln: 1.569 ± 0.048
2.305SerArg: 2.305 ± 0.055
3.121SerSer: 3.121 ± 0.076
2.623SerThr: 2.623 ± 0.064
3.613SerVal: 3.613 ± 0.068
0.461SerTrp: 0.461 ± 0.025
2.161SerTyr: 2.161 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
3.251ThrAla: 3.251 ± 0.065
0.318ThrCys: 0.318 ± 0.022
2.061ThrAsp: 2.061 ± 0.05
2.854ThrGlu: 2.854 ± 0.059
2.156ThrPhe: 2.156 ± 0.055
3.886ThrGly: 3.886 ± 0.068
0.802ThrHis: 0.802 ± 0.032
3.92ThrIle: 3.92 ± 0.085
3.281ThrLys: 3.281 ± 0.062
4.633ThrLeu: 4.633 ± 0.079
0.992ThrMet: 0.992 ± 0.035
1.767ThrAsn: 1.767 ± 0.045
2.248ThrPro: 2.248 ± 0.06
1.127ThrGln: 1.127 ± 0.036
1.69ThrArg: 1.69 ± 0.046
2.825ThrSer: 2.825 ± 0.059
2.334ThrThr: 2.334 ± 0.065
3.881ThrVal: 3.881 ± 0.073
0.35ThrTrp: 0.35 ± 0.021
1.82ThrTyr: 1.82 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
4.933ValAla: 4.933 ± 0.094
0.607ValCys: 0.607 ± 0.03
4.103ValAsp: 4.103 ± 0.073
6.152ValGlu: 6.152 ± 0.1
3.35ValPhe: 3.35 ± 0.081
4.851ValGly: 4.851 ± 0.083
0.955ValHis: 0.955 ± 0.031
6.924ValIle: 6.924 ± 0.101
6.712ValLys: 6.712 ± 0.099
7.27ValLeu: 7.27 ± 0.1
1.918ValMet: 1.918 ± 0.05
3.262ValAsn: 3.262 ± 0.068
2.775ValPro: 2.775 ± 0.067
1.459ValGln: 1.459 ± 0.049
2.93ValArg: 2.93 ± 0.068
4.145ValSer: 4.145 ± 0.082
3.755ValThr: 3.755 ± 0.086
6.151ValVal: 6.151 ± 0.108
0.487ValTrp: 0.487 ± 0.028
2.926ValTyr: 2.926 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.52TrpAla: 0.52 ± 0.031
0.063TrpCys: 0.063 ± 0.009
0.422TrpAsp: 0.422 ± 0.027
0.647TrpGlu: 0.647 ± 0.031
0.396TrpPhe: 0.396 ± 0.023
0.627TrpGly: 0.627 ± 0.031
0.146TrpHis: 0.146 ± 0.015
0.605TrpIle: 0.605 ± 0.034
0.509TrpLys: 0.509 ± 0.026
0.787TrpLeu: 0.787 ± 0.037
0.226TrpMet: 0.226 ± 0.015
0.353TrpAsn: 0.353 ± 0.024
0.235TrpPro: 0.235 ± 0.018
0.308TrpGln: 0.308 ± 0.024
0.382TrpArg: 0.382 ± 0.025
0.369TrpSer: 0.369 ± 0.023
0.342TrpThr: 0.342 ± 0.019
0.516TrpVal: 0.516 ± 0.027
0.114TrpTrp: 0.114 ± 0.013
0.316TrpTyr: 0.316 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.329TyrAla: 2.329 ± 0.064
0.369TyrCys: 0.369 ± 0.023
2.178TyrAsp: 2.178 ± 0.06
2.877TyrGlu: 2.877 ± 0.067
1.959TyrPhe: 1.959 ± 0.05
2.884TyrGly: 2.884 ± 0.062
0.685TyrHis: 0.685 ± 0.027
3.44TyrIle: 3.44 ± 0.071
3.183TyrLys: 3.183 ± 0.066
3.869TyrLeu: 3.869 ± 0.079
0.905TyrMet: 0.905 ± 0.034
1.891TyrAsn: 1.891 ± 0.049
1.489TyrPro: 1.489 ± 0.048
1.022TyrGln: 1.022 ± 0.037
1.803TyrArg: 1.803 ± 0.048
2.196TyrSer: 2.196 ± 0.05
2.024TyrThr: 2.024 ± 0.062
2.953TyrVal: 2.953 ± 0.062
0.318TyrTrp: 0.318 ± 0.022
1.847TyrTyr: 1.847 ± 0.059
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2545 proteins (762176 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski