Amino acid dipepetide frequency for Squash leaf curl China virus - [B]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.833AlaAla: 2.833 ± 1.011
0.567AlaCys: 0.567 ± 0.543
1.7AlaAsp: 1.7 ± 0.884
3.966AlaGlu: 3.966 ± 1.178
1.133AlaPhe: 1.133 ± 0.653
1.7AlaGly: 1.7 ± 0.832
0.567AlaHis: 0.567 ± 0.532
5.099AlaIle: 5.099 ± 1.208
3.966AlaLys: 3.966 ± 1.069
4.533AlaLeu: 4.533 ± 1.569
1.133AlaMet: 1.133 ± 0.653
0.567AlaAsn: 0.567 ± 0.487
3.966AlaPro: 3.966 ± 1.299
1.133AlaGln: 1.133 ± 0.586
3.399AlaArg: 3.399 ± 1.794
5.666AlaSer: 5.666 ± 1.802
3.966AlaThr: 3.966 ± 1.558
2.833AlaVal: 2.833 ± 0.982
1.7AlaTrp: 1.7 ± 0.893
1.7AlaTyr: 1.7 ± 0.914
0.0AlaXaa: 0.0 ± 0.0
Cys
1.133CysAla: 1.133 ± 0.765
0.567CysCys: 0.567 ± 0.487
1.133CysAsp: 1.133 ± 0.686
1.7CysGlu: 1.7 ± 0.788
0.567CysPhe: 0.567 ± 0.586
1.7CysGly: 1.7 ± 1.151
0.567CysHis: 0.567 ± 0.551
1.133CysIle: 1.133 ± 0.649
1.7CysLys: 1.7 ± 0.594
0.567CysLeu: 0.567 ± 0.65
1.7CysMet: 1.7 ± 1.115
2.833CysAsn: 2.833 ± 0.882
1.7CysPro: 1.7 ± 1.308
0.0CysGln: 0.0 ± 0.0
1.7CysArg: 1.7 ± 0.726
2.833CysSer: 2.833 ± 0.896
1.133CysThr: 1.133 ± 0.734
0.567CysVal: 0.567 ± 0.543
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.399AspAla: 3.399 ± 1.531
0.0AspCys: 0.0 ± 0.0
1.133AspAsp: 1.133 ± 0.765
3.399AspGlu: 3.399 ± 0.865
1.7AspPhe: 1.7 ± 0.872
2.833AspGly: 2.833 ± 1.401
1.133AspHis: 1.133 ± 0.747
3.399AspIle: 3.399 ± 1.641
2.266AspLys: 2.266 ± 0.668
3.966AspLeu: 3.966 ± 1.487
1.133AspMet: 1.133 ± 0.614
2.266AspAsn: 2.266 ± 0.848
2.266AspPro: 2.266 ± 0.668
0.567AspGln: 0.567 ± 0.432
3.399AspArg: 3.399 ± 1.444
2.266AspSer: 2.266 ± 1.024
1.133AspThr: 1.133 ± 0.715
7.932AspVal: 7.932 ± 1.678
1.7AspTrp: 1.7 ± 1.061
0.567AspTyr: 0.567 ± 0.487
0.0AspXaa: 0.0 ± 0.0
Glu
1.7GluAla: 1.7 ± 0.723
0.0GluCys: 0.0 ± 0.0
1.133GluAsp: 1.133 ± 0.975
6.232GluGlu: 6.232 ± 3.356
2.833GluPhe: 2.833 ± 1.471
2.833GluGly: 2.833 ± 0.828
1.7GluHis: 1.7 ± 0.914
2.833GluIle: 2.833 ± 2.082
1.7GluLys: 1.7 ± 0.859
2.266GluLeu: 2.266 ± 1.443
0.0GluMet: 0.0 ± 0.0
2.266GluAsn: 2.266 ± 1.663
1.133GluPro: 1.133 ± 0.555
2.266GluGln: 2.266 ± 1.17
1.7GluArg: 1.7 ± 0.919
6.232GluSer: 6.232 ± 1.291
1.7GluThr: 1.7 ± 0.726
3.966GluVal: 3.966 ± 0.943
1.133GluTrp: 1.133 ± 0.691
3.399GluTyr: 3.399 ± 1.5
0.0GluXaa: 0.0 ± 0.0
Phe
0.567PheAla: 0.567 ± 0.532
1.133PheCys: 1.133 ± 0.72
2.266PheAsp: 2.266 ± 1.111
1.7PheGlu: 1.7 ± 0.594
1.133PhePhe: 1.133 ± 0.555
2.266PheGly: 2.266 ± 1.338
1.7PheHis: 1.7 ± 1.059
2.833PheIle: 2.833 ± 1.122
3.399PheLys: 3.399 ± 1.539
2.833PheLeu: 2.833 ± 1.007
0.567PheMet: 0.567 ± 0.487
1.7PheAsn: 1.7 ± 0.872
3.399PhePro: 3.399 ± 1.179
2.266PheGln: 2.266 ± 1.156
0.567PheArg: 0.567 ± 0.531
2.833PheSer: 2.833 ± 0.976
3.399PheThr: 3.399 ± 1.302
2.833PheVal: 2.833 ± 1.379
0.567PheTrp: 0.567 ± 0.531
1.7PheTyr: 1.7 ± 0.806
0.0PheXaa: 0.0 ± 0.0
Gly
2.833GlyAla: 2.833 ± 1.544
1.7GlyCys: 1.7 ± 0.717
3.399GlyAsp: 3.399 ± 1.138
1.133GlyGlu: 1.133 ± 0.764
1.7GlyPhe: 1.7 ± 0.78
2.266GlyGly: 2.266 ± 0.814
1.7GlyHis: 1.7 ± 1.004
2.833GlyIle: 2.833 ± 1.482
5.666GlyLys: 5.666 ± 2.312
7.365GlyLeu: 7.365 ± 1.939
0.0GlyMet: 0.0 ± 0.406
1.7GlyAsn: 1.7 ± 1.122
3.966GlyPro: 3.966 ± 1.264
0.567GlyGln: 0.567 ± 0.487
2.266GlyArg: 2.266 ± 1.051
5.666GlySer: 5.666 ± 2.106
5.099GlyThr: 5.099 ± 1.96
3.966GlyVal: 3.966 ± 1.529
0.567GlyTrp: 0.567 ± 0.432
1.133GlyTyr: 1.133 ± 0.715
0.0GlyXaa: 0.0 ± 0.0
His
1.133HisAla: 1.133 ± 1.087
1.7HisCys: 1.7 ± 0.832
2.833HisAsp: 2.833 ± 1.416
1.133HisGlu: 1.133 ± 0.71
2.833HisPhe: 2.833 ± 1.371
2.266HisGly: 2.266 ± 1.26
1.7HisHis: 1.7 ± 1.098
2.266HisIle: 2.266 ± 1.119
1.133HisLys: 1.133 ± 0.808
2.833HisLeu: 2.833 ± 1.489
0.0HisMet: 0.0 ± 0.0
2.833HisAsn: 2.833 ± 1.157
1.7HisPro: 1.7 ± 1.122
1.7HisGln: 1.7 ± 0.818
3.399HisArg: 3.399 ± 1.46
2.266HisSer: 2.266 ± 1.172
1.7HisThr: 1.7 ± 1.177
2.833HisVal: 2.833 ± 1.101
0.0HisTrp: 0.0 ± 0.0
1.133HisTyr: 1.133 ± 0.583
0.0HisXaa: 0.0 ± 0.0
Ile
1.7IleAla: 1.7 ± 0.595
1.7IleCys: 1.7 ± 0.741
4.533IleAsp: 4.533 ± 1.773
2.833IleGlu: 2.833 ± 1.4
3.966IlePhe: 3.966 ± 1.377
2.833IleGly: 2.833 ± 0.637
2.266IleHis: 2.266 ± 0.76
3.966IleIle: 3.966 ± 1.563
4.533IleLys: 4.533 ± 1.181
3.399IleLeu: 3.399 ± 1.714
0.0IleMet: 0.0 ± 0.0
2.266IleAsn: 2.266 ± 0.749
2.266IlePro: 2.266 ± 0.749
1.7IleGln: 1.7 ± 0.935
4.533IleArg: 4.533 ± 1.357
5.099IleSer: 5.099 ± 1.131
5.666IleThr: 5.666 ± 2.313
2.266IleVal: 2.266 ± 0.981
2.266IleTrp: 2.266 ± 1.416
2.833IleTyr: 2.833 ± 1.413
0.0IleXaa: 0.0 ± 0.0
Lys
2.266LysAla: 2.266 ± 0.946
1.7LysCys: 1.7 ± 0.813
2.266LysAsp: 2.266 ± 0.899
3.966LysGlu: 3.966 ± 2.239
2.833LysPhe: 2.833 ± 0.915
3.966LysGly: 3.966 ± 1.071
2.266LysHis: 2.266 ± 1.058
5.099LysIle: 5.099 ± 0.854
3.399LysLys: 3.399 ± 1.644
2.266LysLeu: 2.266 ± 1.189
1.7LysMet: 1.7 ± 0.744
6.799LysAsn: 6.799 ± 1.446
1.7LysPro: 1.7 ± 0.594
2.266LysGln: 2.266 ± 0.974
1.7LysArg: 1.7 ± 1.177
3.966LysSer: 3.966 ± 0.785
5.099LysThr: 5.099 ± 1.249
3.399LysVal: 3.399 ± 1.415
0.567LysTrp: 0.567 ± 0.543
3.399LysTyr: 3.399 ± 0.844
0.0LysXaa: 0.0 ± 0.0
Leu
1.7LeuAla: 1.7 ± 0.702
1.7LeuCys: 1.7 ± 1.059
5.666LeuAsp: 5.666 ± 1.483
3.966LeuGlu: 3.966 ± 1.74
2.266LeuPhe: 2.266 ± 1.088
3.966LeuGly: 3.966 ± 0.982
2.833LeuHis: 2.833 ± 0.898
3.966LeuIle: 3.966 ± 1.635
5.666LeuLys: 5.666 ± 1.929
1.133LeuLeu: 1.133 ± 0.614
2.833LeuMet: 2.833 ± 0.893
4.533LeuAsn: 4.533 ± 1.644
2.833LeuPro: 2.833 ± 1.592
2.266LeuGln: 2.266 ± 0.835
6.232LeuArg: 6.232 ± 2.246
4.533LeuSer: 4.533 ± 1.273
5.666LeuThr: 5.666 ± 1.732
4.533LeuVal: 4.533 ± 1.346
0.567LeuTrp: 0.567 ± 0.532
2.833LeuTyr: 2.833 ± 0.901
0.0LeuXaa: 0.0 ± 0.0
Met
1.7MetAla: 1.7 ± 0.595
1.7MetCys: 1.7 ± 0.832
0.567MetAsp: 0.567 ± 0.543
0.0MetGlu: 0.0 ± 0.0
1.133MetPhe: 1.133 ± 0.72
2.266MetGly: 2.266 ± 0.948
1.7MetHis: 1.7 ± 0.925
1.133MetIle: 1.133 ± 0.765
2.833MetLys: 2.833 ± 1.225
2.266MetLeu: 2.266 ± 0.817
0.0MetMet: 0.0 ± 0.0
1.7MetAsn: 1.7 ± 0.723
0.567MetPro: 0.567 ± 0.532
0.567MetGln: 0.567 ± 0.551
1.133MetArg: 1.133 ± 0.72
2.266MetSer: 2.266 ± 0.889
1.133MetThr: 1.133 ± 0.863
0.0MetVal: 0.0 ± 0.0
0.567MetTrp: 0.567 ± 0.586
1.7MetTyr: 1.7 ± 1.116
0.0MetXaa: 0.0 ± 0.0
Asn
5.099AsnAla: 5.099 ± 1.105
2.266AsnCys: 2.266 ± 0.776
2.833AsnAsp: 2.833 ± 1.554
1.133AsnGlu: 1.133 ± 0.72
2.266AsnPhe: 2.266 ± 0.877
1.7AsnGly: 1.7 ± 0.807
2.266AsnHis: 2.266 ± 1.228
3.399AsnIle: 3.399 ± 1.192
2.266AsnLys: 2.266 ± 1.114
3.399AsnLeu: 3.399 ± 1.104
3.966AsnMet: 3.966 ± 1.393
3.399AsnAsn: 3.399 ± 1.108
1.7AsnPro: 1.7 ± 0.883
2.266AsnGln: 2.266 ± 0.877
5.666AsnArg: 5.666 ± 1.096
2.833AsnSer: 2.833 ± 0.915
3.399AsnThr: 3.399 ± 1.015
3.966AsnVal: 3.966 ± 1.072
0.0AsnTrp: 0.0 ± 0.0
2.833AsnTyr: 2.833 ± 0.915
0.0AsnXaa: 0.0 ± 0.0
Pro
2.266ProAla: 2.266 ± 1.215
2.266ProCys: 2.266 ± 0.946
1.133ProAsp: 1.133 ± 0.766
0.567ProGlu: 0.567 ± 0.586
1.7ProPhe: 1.7 ± 0.726
1.7ProGly: 1.7 ± 0.67
3.966ProHis: 3.966 ± 1.516
3.399ProIle: 3.399 ± 0.865
3.399ProLys: 3.399 ± 1.295
4.533ProLeu: 4.533 ± 1.353
1.133ProMet: 1.133 ± 0.766
4.533ProAsn: 4.533 ± 1.328
1.7ProPro: 1.7 ± 1.106
2.833ProGln: 2.833 ± 0.658
3.966ProArg: 3.966 ± 1.188
3.399ProSer: 3.399 ± 1.03
3.399ProThr: 3.399 ± 0.881
2.833ProVal: 2.833 ± 1.106
1.133ProTrp: 1.133 ± 0.63
2.266ProTyr: 2.266 ± 0.765
0.0ProXaa: 0.0 ± 0.0
Gln
1.7GlnAla: 1.7 ± 0.834
1.133GlnCys: 1.133 ± 0.583
2.266GlnAsp: 2.266 ± 1.532
1.7GlnGlu: 1.7 ± 0.723
1.133GlnPhe: 1.133 ± 0.975
1.7GlnGly: 1.7 ± 0.76
0.0GlnHis: 0.0 ± 0.0
1.133GlnIle: 1.133 ± 0.765
1.7GlnLys: 1.7 ± 0.807
2.266GlnLeu: 2.266 ± 0.668
0.567GlnMet: 0.567 ± 0.551
1.7GlnAsn: 1.7 ± 0.78
3.966GlnPro: 3.966 ± 1.844
1.7GlnGln: 1.7 ± 0.595
0.567GlnArg: 0.567 ± 0.487
2.833GlnSer: 2.833 ± 1.147
2.833GlnThr: 2.833 ± 0.974
3.399GlnVal: 3.399 ± 1.565
0.567GlnTrp: 0.567 ± 0.487
1.133GlnTyr: 1.133 ± 0.586
0.0GlnXaa: 0.0 ± 0.0
Arg
5.099ArgAla: 5.099 ± 1.438
2.266ArgCys: 2.266 ± 0.801
2.833ArgAsp: 2.833 ± 0.587
2.833ArgGlu: 2.833 ± 0.947
3.399ArgPhe: 3.399 ± 1.577
3.966ArgGly: 3.966 ± 1.329
3.399ArgHis: 3.399 ± 1.437
2.833ArgIle: 2.833 ± 0.746
3.966ArgLys: 3.966 ± 1.883
5.099ArgLeu: 5.099 ± 1.737
0.567ArgMet: 0.567 ± 0.543
2.833ArgAsn: 2.833 ± 1.503
5.099ArgPro: 5.099 ± 1.26
1.133ArgGln: 1.133 ± 0.684
5.099ArgArg: 5.099 ± 2.147
4.533ArgSer: 4.533 ± 1.457
3.966ArgThr: 3.966 ± 1.491
7.365ArgVal: 7.365 ± 1.734
0.0ArgTrp: 0.0 ± 0.0
2.266ArgTyr: 2.266 ± 1.042
0.0ArgXaa: 0.0 ± 0.0
Ser
6.232SerAla: 6.232 ± 1.819
2.266SerCys: 2.266 ± 1.252
2.266SerAsp: 2.266 ± 0.878
1.7SerGlu: 1.7 ± 1.064
1.133SerPhe: 1.133 ± 0.555
3.399SerGly: 3.399 ± 0.941
0.567SerHis: 0.567 ± 0.543
6.232SerIle: 6.232 ± 1.527
4.533SerLys: 4.533 ± 1.457
3.966SerLeu: 3.966 ± 1.543
1.133SerMet: 1.133 ± 0.596
3.966SerAsn: 3.966 ± 1.185
4.533SerPro: 4.533 ± 1.306
5.099SerGln: 5.099 ± 1.996
10.765SerArg: 10.765 ± 2.032
7.365SerSer: 7.365 ± 2.58
5.099SerThr: 5.099 ± 1.699
5.666SerVal: 5.666 ± 1.781
0.567SerTrp: 0.567 ± 0.531
2.833SerTyr: 2.833 ± 0.971
0.0SerXaa: 0.0 ± 0.0
Thr
4.533ThrAla: 4.533 ± 1.481
0.0ThrCys: 0.0 ± 0.0
2.266ThrAsp: 2.266 ± 1.033
1.7ThrGlu: 1.7 ± 1.143
2.266ThrPhe: 2.266 ± 1.033
6.799ThrGly: 6.799 ± 2.066
2.833ThrHis: 2.833 ± 1.083
2.266ThrIle: 2.266 ± 1.058
3.966ThrLys: 3.966 ± 1.505
3.966ThrLeu: 3.966 ± 0.838
1.7ThrMet: 1.7 ± 0.724
5.099ThrAsn: 5.099 ± 1.87
3.966ThrPro: 3.966 ± 1.42
1.7ThrGln: 1.7 ± 0.831
4.533ThrArg: 4.533 ± 1.472
5.099ThrSer: 5.099 ± 1.628
1.7ThrThr: 1.7 ± 0.925
3.966ThrVal: 3.966 ± 1.408
1.133ThrTrp: 1.133 ± 0.684
3.399ThrTyr: 3.399 ± 0.888
0.0ThrXaa: 0.0 ± 0.0
Val
1.133ValAla: 1.133 ± 0.696
0.567ValCys: 0.567 ± 0.532
2.833ValAsp: 2.833 ± 0.983
6.232ValGlu: 6.232 ± 2.737
2.833ValPhe: 2.833 ± 1.347
5.666ValGly: 5.666 ± 2.354
3.399ValHis: 3.399 ± 1.577
3.399ValIle: 3.399 ± 1.162
2.833ValLys: 2.833 ± 1.047
8.499ValLeu: 8.499 ± 2.219
3.399ValMet: 3.399 ± 0.925
3.399ValAsn: 3.399 ± 1.485
4.533ValPro: 4.533 ± 1.017
2.833ValGln: 2.833 ± 1.249
3.966ValArg: 3.966 ± 1.946
3.966ValSer: 3.966 ± 1.155
3.966ValThr: 3.966 ± 2.269
4.533ValVal: 4.533 ± 1.393
1.133ValTrp: 1.133 ± 0.723
3.966ValTyr: 3.966 ± 1.464
0.0ValXaa: 0.0 ± 0.0
Trp
2.833TrpAla: 2.833 ± 0.876
0.0TrpCys: 0.0 ± 0.0
1.133TrpAsp: 1.133 ± 0.757
0.567TrpGlu: 0.567 ± 0.65
0.0TrpPhe: 0.0 ± 0.0
1.133TrpGly: 1.133 ± 0.71
1.133TrpHis: 1.133 ± 0.734
0.0TrpIle: 0.0 ± 0.0
0.567TrpLys: 0.567 ± 0.432
0.567TrpLeu: 0.567 ± 0.432
0.567TrpMet: 0.567 ± 0.543
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.567TrpGln: 0.567 ± 0.487
1.133TrpArg: 1.133 ± 0.747
1.133TrpSer: 1.133 ± 0.63
1.7TrpThr: 1.7 ± 1.31
0.567TrpVal: 0.567 ± 0.487
0.0TrpTrp: 0.0 ± 0.0
0.567TrpTyr: 0.567 ± 0.487
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.266TyrAla: 2.266 ± 0.978
0.0TyrCys: 0.0 ± 0.0
2.266TyrAsp: 2.266 ± 1.026
0.567TyrGlu: 0.567 ± 0.543
2.833TyrPhe: 2.833 ± 0.762
1.133TyrGly: 1.133 ± 0.586
1.7TyrHis: 1.7 ± 0.831
3.399TyrIle: 3.399 ± 1.373
1.133TyrLys: 1.133 ± 0.583
3.966TyrLeu: 3.966 ± 1.536
2.266TyrMet: 2.266 ± 0.875
2.266TyrAsn: 2.266 ± 0.967
1.133TyrPro: 1.133 ± 0.586
0.567TyrGln: 0.567 ± 0.543
2.833TyrArg: 2.833 ± 1.4
4.533TyrSer: 4.533 ± 1.996
1.133TyrThr: 1.133 ± 0.863
5.666TyrVal: 5.666 ± 1.814
0.0TyrTrp: 0.0 ± 0.0
2.266TyrTyr: 2.266 ± 0.861
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1766 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski