Amino acid dipepetide frequency for Wuhan Louse Fly Virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.943AlaAla: 1.943 ± 1.174
0.0AlaCys: 0.0 ± 0.0
3.053AlaAsp: 3.053 ± 0.716
1.943AlaGlu: 1.943 ± 0.793
1.11AlaPhe: 1.11 ± 0.365
1.388AlaGly: 1.388 ± 0.904
1.11AlaHis: 1.11 ± 0.765
2.775AlaIle: 2.775 ± 0.361
2.498AlaLys: 2.498 ± 0.97
4.718AlaLeu: 4.718 ± 1.651
0.0AlaMet: 0.0 ± 0.0
3.331AlaAsn: 3.331 ± 1.461
1.943AlaPro: 1.943 ± 0.353
1.11AlaGln: 1.11 ± 0.504
1.388AlaArg: 1.388 ± 0.326
3.608AlaSer: 3.608 ± 0.809
1.388AlaThr: 1.388 ± 0.507
2.498AlaVal: 2.498 ± 0.37
0.0AlaTrp: 0.0 ± 0.0
0.555AlaTyr: 0.555 ± 0.328
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.833CysAsp: 0.833 ± 0.367
1.388CysGlu: 1.388 ± 0.979
0.278CysPhe: 0.278 ± 0.164
0.833CysGly: 0.833 ± 0.328
1.11CysHis: 1.11 ± 0.62
0.278CysIle: 0.278 ± 0.459
0.833CysLys: 0.833 ± 1.116
2.775CysLeu: 2.775 ± 0.816
0.278CysMet: 0.278 ± 0.459
0.833CysAsn: 0.833 ± 0.455
0.833CysPro: 0.833 ± 0.517
0.555CysGln: 0.555 ± 0.328
0.278CysArg: 0.278 ± 0.164
2.22CysSer: 2.22 ± 0.319
0.555CysThr: 0.555 ± 0.382
1.11CysVal: 1.11 ± 0.656
0.833CysTrp: 0.833 ± 0.492
0.278CysTyr: 0.278 ± 0.164
0.0CysXaa: 0.0 ± 0.0
Asp
1.11AspAla: 1.11 ± 0.415
0.278AspCys: 0.278 ± 0.164
2.22AspAsp: 2.22 ± 0.319
2.775AspGlu: 2.775 ± 1.087
3.331AspPhe: 3.331 ± 1.399
2.22AspGly: 2.22 ± 0.692
1.943AspHis: 1.943 ± 0.73
3.053AspIle: 3.053 ± 0.799
3.608AspLys: 3.608 ± 0.836
6.106AspLeu: 6.106 ± 1.348
1.11AspMet: 1.11 ± 0.781
2.775AspAsn: 2.775 ± 1.64
6.106AspPro: 6.106 ± 1.697
1.388AspGln: 1.388 ± 0.82
1.388AspArg: 1.388 ± 0.524
3.608AspSer: 3.608 ± 1.343
3.053AspThr: 3.053 ± 0.836
1.943AspVal: 1.943 ± 0.764
1.11AspTrp: 1.11 ± 0.825
2.498AspTyr: 2.498 ± 1.051
0.0AspXaa: 0.0 ± 0.0
Glu
2.775GluAla: 2.775 ± 0.706
0.833GluCys: 0.833 ± 0.328
2.22GluAsp: 2.22 ± 0.796
3.886GluGlu: 3.886 ± 1.277
2.22GluPhe: 2.22 ± 0.68
3.886GluGly: 3.886 ± 1.795
0.0GluHis: 0.0 ± 0.0
4.996GluIle: 4.996 ± 1.232
4.441GluLys: 4.441 ± 1.4
4.441GluLeu: 4.441 ± 1.125
1.11GluMet: 1.11 ± 0.819
2.22GluAsn: 2.22 ± 1.507
1.943GluPro: 1.943 ± 1.134
1.388GluGln: 1.388 ± 0.671
2.775GluArg: 2.775 ± 1.032
3.608GluSer: 3.608 ± 0.412
2.775GluThr: 2.775 ± 0.892
5.273GluVal: 5.273 ± 1.181
1.665GluTrp: 1.665 ± 1.761
2.498GluTyr: 2.498 ± 1.005
0.0GluXaa: 0.0 ± 0.0
Phe
2.22PheAla: 2.22 ± 0.843
0.278PheCys: 0.278 ± 0.459
1.665PheAsp: 1.665 ± 0.635
1.388PheGlu: 1.388 ± 0.524
0.833PhePhe: 0.833 ± 0.462
2.498PheGly: 2.498 ± 0.808
0.555PheHis: 0.555 ± 0.328
2.498PheIle: 2.498 ± 1.116
4.163PheLys: 4.163 ± 0.629
5.828PheLeu: 5.828 ± 1.131
1.665PheMet: 1.665 ± 0.641
2.498PheAsn: 2.498 ± 0.65
3.331PhePro: 3.331 ± 1.092
2.22PheGln: 2.22 ± 1.312
1.665PheArg: 1.665 ± 0.366
3.608PheSer: 3.608 ± 0.817
2.22PheThr: 2.22 ± 0.459
2.498PheVal: 2.498 ± 0.39
0.555PheTrp: 0.555 ± 0.478
1.943PheTyr: 1.943 ± 0.743
0.0PheXaa: 0.0 ± 0.0
Gly
2.498GlyAla: 2.498 ± 1.07
0.555GlyCys: 0.555 ± 0.382
2.775GlyAsp: 2.775 ± 0.726
2.498GlyGlu: 2.498 ± 1.104
2.775GlyPhe: 2.775 ± 0.82
2.775GlyGly: 2.775 ± 1.29
1.665GlyHis: 1.665 ± 0.681
3.886GlyIle: 3.886 ± 1.063
1.943GlyLys: 1.943 ± 0.573
6.106GlyLeu: 6.106 ± 1.271
1.11GlyMet: 1.11 ± 0.422
3.608GlyAsn: 3.608 ± 0.738
2.22GlyPro: 2.22 ± 0.692
1.665GlyGln: 1.665 ± 0.984
2.22GlyArg: 2.22 ± 0.937
6.661GlySer: 6.661 ± 1.375
2.22GlyThr: 2.22 ± 1.372
3.053GlyVal: 3.053 ± 0.802
0.555GlyTrp: 0.555 ± 0.328
1.943GlyTyr: 1.943 ± 0.463
0.0GlyXaa: 0.0 ± 0.0
His
1.11HisAla: 1.11 ± 0.422
0.0HisCys: 0.0 ± 0.0
0.833HisAsp: 0.833 ± 0.492
0.555HisGlu: 0.555 ± 0.382
1.11HisPhe: 1.11 ± 0.656
1.388HisGly: 1.388 ± 0.54
0.278HisHis: 0.278 ± 0.372
2.498HisIle: 2.498 ± 0.791
1.665HisLys: 1.665 ± 0.721
3.331HisLeu: 3.331 ± 0.488
0.278HisMet: 0.278 ± 0.459
0.833HisAsn: 0.833 ± 0.665
2.498HisPro: 2.498 ± 0.747
1.665HisGln: 1.665 ± 0.446
1.665HisArg: 1.665 ± 0.984
1.665HisSer: 1.665 ± 0.366
0.833HisThr: 0.833 ± 0.665
1.943HisVal: 1.943 ± 0.73
0.833HisTrp: 0.833 ± 0.492
0.833HisTyr: 0.833 ± 0.328
0.0HisXaa: 0.0 ± 0.0
Ile
0.833IleAla: 0.833 ± 0.492
1.11IleCys: 1.11 ± 0.365
5.273IleAsp: 5.273 ± 1.171
5.551IleGlu: 5.551 ± 1.088
3.608IlePhe: 3.608 ± 0.871
5.828IleGly: 5.828 ± 1.106
1.665IleHis: 1.665 ± 0.98
5.551IleIle: 5.551 ± 1.723
6.106IleLys: 6.106 ± 1.718
7.494IleLeu: 7.494 ± 1.371
0.555IleMet: 0.555 ± 0.328
2.498IleAsn: 2.498 ± 0.891
3.608IlePro: 3.608 ± 0.458
3.608IleGln: 3.608 ± 1.516
5.273IleArg: 5.273 ± 1.283
5.551IleSer: 5.551 ± 1.258
5.551IleThr: 5.551 ± 1.789
4.163IleVal: 4.163 ± 0.972
1.11IleTrp: 1.11 ± 0.656
2.22IleTyr: 2.22 ± 0.827
0.0IleXaa: 0.0 ± 0.0
Lys
1.665LysAla: 1.665 ± 0.778
0.555LysCys: 0.555 ± 0.328
3.886LysAsp: 3.886 ± 0.797
4.996LysGlu: 4.996 ± 1.279
1.943LysPhe: 1.943 ± 1.038
4.441LysGly: 4.441 ± 1.244
2.498LysHis: 2.498 ± 0.943
4.441LysIle: 4.441 ± 1.617
3.886LysLys: 3.886 ± 1.166
7.771LysLeu: 7.771 ± 3.212
0.833LysMet: 0.833 ± 0.367
3.331LysAsn: 3.331 ± 1.636
3.053LysPro: 3.053 ± 1.208
2.498LysGln: 2.498 ± 0.585
3.053LysArg: 3.053 ± 0.84
3.331LysSer: 3.331 ± 0.855
4.163LysThr: 4.163 ± 0.552
3.886LysVal: 3.886 ± 0.73
1.11LysTrp: 1.11 ± 0.656
1.11LysTyr: 1.11 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
4.441LeuAla: 4.441 ± 1.076
2.498LeuCys: 2.498 ± 0.637
6.106LeuAsp: 6.106 ± 1.086
5.828LeuGlu: 5.828 ± 1.819
4.441LeuPhe: 4.441 ± 1.548
4.996LeuGly: 4.996 ± 1.243
1.943LeuHis: 1.943 ± 0.566
11.657LeuIle: 11.657 ± 2.956
6.106LeuLys: 6.106 ± 1.848
13.6LeuLeu: 13.6 ± 2.7
1.665LeuMet: 1.665 ± 0.406
6.939LeuAsn: 6.939 ± 1.927
3.053LeuPro: 3.053 ± 1.618
4.163LeuGln: 4.163 ± 1.095
4.996LeuArg: 4.996 ± 1.827
11.102LeuSer: 11.102 ± 1.665
6.384LeuThr: 6.384 ± 1.829
5.828LeuVal: 5.828 ± 2.81
0.0LeuTrp: 0.0 ± 0.0
4.718LeuTyr: 4.718 ± 0.698
0.0LeuXaa: 0.0 ± 0.0
Met
1.388MetAla: 1.388 ± 0.732
0.555MetCys: 0.555 ± 0.382
0.278MetAsp: 0.278 ± 0.164
1.943MetGlu: 1.943 ± 0.582
0.833MetPhe: 0.833 ± 0.829
1.11MetGly: 1.11 ± 0.656
0.278MetHis: 0.278 ± 0.525
1.388MetIle: 1.388 ± 0.54
1.665MetLys: 1.665 ± 0.778
1.943MetLeu: 1.943 ± 1.481
0.833MetMet: 0.833 ± 0.829
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.278MetGln: 0.278 ± 0.525
1.11MetArg: 1.11 ± 0.556
1.388MetSer: 1.388 ± 1.207
1.388MetThr: 1.388 ± 0.905
0.833MetVal: 0.833 ± 0.367
0.278MetTrp: 0.278 ± 0.164
0.833MetTyr: 0.833 ± 0.462
0.0MetXaa: 0.0 ± 0.0
Asn
1.665AsnAla: 1.665 ± 0.894
1.388AsnCys: 1.388 ± 0.656
3.331AsnAsp: 3.331 ± 0.761
1.11AsnGlu: 1.11 ± 0.776
1.943AsnPhe: 1.943 ± 0.52
1.11AsnGly: 1.11 ± 0.62
1.388AsnHis: 1.388 ± 0.326
4.996AsnIle: 4.996 ± 1.921
2.775AsnLys: 2.775 ± 1.066
6.939AsnLeu: 6.939 ± 0.894
0.278AsnMet: 0.278 ± 0.164
4.163AsnAsn: 4.163 ± 0.926
3.331AsnPro: 3.331 ± 1.194
2.498AsnGln: 2.498 ± 0.624
1.665AsnArg: 1.665 ± 0.406
5.551AsnSer: 5.551 ± 0.824
3.886AsnThr: 3.886 ± 0.637
2.775AsnVal: 2.775 ± 0.788
1.665AsnTrp: 1.665 ± 0.681
4.718AsnTyr: 4.718 ± 0.698
0.0AsnXaa: 0.0 ± 0.0
Pro
1.943ProAla: 1.943 ± 0.533
0.278ProCys: 0.278 ± 0.372
3.331ProAsp: 3.331 ± 1.669
1.665ProGlu: 1.665 ± 0.826
1.943ProPhe: 1.943 ± 1.069
1.388ProGly: 1.388 ± 0.968
1.665ProHis: 1.665 ± 0.68
3.886ProIle: 3.886 ± 1.203
3.331ProLys: 3.331 ± 0.886
4.996ProLeu: 4.996 ± 1.0
1.11ProMet: 1.11 ± 0.422
3.331ProAsn: 3.331 ± 0.772
3.886ProPro: 3.886 ± 4.99
1.388ProGln: 1.388 ± 1.39
2.775ProArg: 2.775 ± 0.828
7.494ProSer: 7.494 ± 2.441
2.775ProThr: 2.775 ± 1.027
3.331ProVal: 3.331 ± 1.603
0.833ProTrp: 0.833 ± 0.873
1.665ProTyr: 1.665 ± 0.366
0.0ProXaa: 0.0 ± 0.0
Gln
1.11GlnAla: 1.11 ± 0.556
0.278GlnCys: 0.278 ± 0.372
2.775GlnAsp: 2.775 ± 1.236
2.22GlnGlu: 2.22 ± 0.664
1.943GlnPhe: 1.943 ± 0.577
3.608GlnGly: 3.608 ± 1.21
0.833GlnHis: 0.833 ± 0.492
1.943GlnIle: 1.943 ± 0.774
1.943GlnLys: 1.943 ± 0.77
3.886GlnLeu: 3.886 ± 0.506
0.833GlnMet: 0.833 ± 0.499
2.22GlnAsn: 2.22 ± 0.985
1.11GlnPro: 1.11 ± 0.637
1.943GlnGln: 1.943 ± 2.026
2.22GlnArg: 2.22 ± 0.68
2.498GlnSer: 2.498 ± 0.65
4.441GlnThr: 4.441 ± 2.417
1.665GlnVal: 1.665 ± 0.412
0.0GlnTrp: 0.0 ± 0.0
1.11GlnTyr: 1.11 ± 0.868
0.0GlnXaa: 0.0 ± 0.0
Arg
1.943ArgAla: 1.943 ± 0.899
0.278ArgCys: 0.278 ± 0.525
1.665ArgAsp: 1.665 ± 0.681
3.608ArgGlu: 3.608 ± 1.109
3.886ArgPhe: 3.886 ± 0.983
3.331ArgGly: 3.331 ± 0.855
1.388ArgHis: 1.388 ± 0.54
2.22ArgIle: 2.22 ± 0.854
2.498ArgLys: 2.498 ± 1.014
4.163ArgLeu: 4.163 ± 1.346
1.388ArgMet: 1.388 ± 0.656
3.053ArgAsn: 3.053 ± 0.823
1.388ArgPro: 1.388 ± 0.595
2.22ArgGln: 2.22 ± 0.989
1.388ArgArg: 1.388 ± 1.504
3.608ArgSer: 3.608 ± 1.278
1.665ArgThr: 1.665 ± 0.713
3.053ArgVal: 3.053 ± 0.799
1.11ArgTrp: 1.11 ± 0.955
1.665ArgTyr: 1.665 ± 0.366
0.0ArgXaa: 0.0 ± 0.0
Ser
3.331SerAla: 3.331 ± 0.814
2.775SerCys: 2.775 ± 0.572
3.608SerAsp: 3.608 ± 1.766
3.608SerGlu: 3.608 ± 1.053
3.331SerPhe: 3.331 ± 0.836
3.331SerGly: 3.331 ± 1.949
2.498SerHis: 2.498 ± 0.637
8.881SerIle: 8.881 ± 1.73
5.273SerLys: 5.273 ± 2.187
9.992SerLeu: 9.992 ± 2.315
0.278SerMet: 0.278 ± 0.459
5.551SerAsn: 5.551 ± 2.585
4.718SerPro: 4.718 ± 1.335
2.498SerGln: 2.498 ± 0.528
2.22SerArg: 2.22 ± 0.372
5.551SerSer: 5.551 ± 0.605
6.939SerThr: 6.939 ± 1.312
5.551SerVal: 5.551 ± 1.025
3.053SerTrp: 3.053 ± 1.142
2.498SerTyr: 2.498 ± 1.488
0.0SerXaa: 0.0 ± 0.0
Thr
1.388ThrAla: 1.388 ± 0.513
1.388ThrCys: 1.388 ± 0.54
2.775ThrAsp: 2.775 ± 0.944
2.775ThrGlu: 2.775 ± 1.301
1.665ThrPhe: 1.665 ± 0.655
3.053ThrGly: 3.053 ± 1.171
1.11ThrHis: 1.11 ± 0.422
4.441ThrIle: 4.441 ± 1.275
3.053ThrLys: 3.053 ± 1.461
6.384ThrLeu: 6.384 ± 2.207
2.22ThrMet: 2.22 ± 1.106
3.886ThrAsn: 3.886 ± 1.133
3.886ThrPro: 3.886 ± 1.911
2.775ThrGln: 2.775 ± 1.916
3.608ThrArg: 3.608 ± 0.696
4.163ThrSer: 4.163 ± 1.145
3.886ThrThr: 3.886 ± 0.962
3.331ThrVal: 3.331 ± 1.922
0.555ThrTrp: 0.555 ± 0.328
3.331ThrTyr: 3.331 ± 0.968
0.0ThrXaa: 0.0 ± 0.0
Val
2.498ValAla: 2.498 ± 0.747
1.943ValCys: 1.943 ± 0.943
2.22ValAsp: 2.22 ± 0.985
3.886ValGlu: 3.886 ± 2.704
2.498ValPhe: 2.498 ± 0.714
2.498ValGly: 2.498 ± 0.774
2.22ValHis: 2.22 ± 0.683
4.718ValIle: 4.718 ± 2.007
4.163ValLys: 4.163 ± 1.733
3.608ValLeu: 3.608 ± 0.71
1.11ValMet: 1.11 ± 0.656
3.331ValAsn: 3.331 ± 1.203
3.053ValPro: 3.053 ± 1.21
2.22ValGln: 2.22 ± 1.946
2.498ValArg: 2.498 ± 0.478
6.384ValSer: 6.384 ± 1.523
3.331ValThr: 3.331 ± 1.911
2.498ValVal: 2.498 ± 0.747
0.278ValTrp: 0.278 ± 0.372
1.665ValTyr: 1.665 ± 0.655
0.0ValXaa: 0.0 ± 0.0
Trp
0.555TrpAla: 0.555 ± 0.919
0.278TrpCys: 0.278 ± 0.518
0.833TrpAsp: 0.833 ± 0.328
1.11TrpGlu: 1.11 ± 0.656
1.665TrpPhe: 1.665 ± 0.735
1.388TrpGly: 1.388 ± 0.656
0.278TrpHis: 0.278 ± 0.164
1.388TrpIle: 1.388 ± 0.955
1.11TrpLys: 1.11 ± 0.62
1.665TrpLeu: 1.665 ± 1.33
0.278TrpMet: 0.278 ± 0.164
1.11TrpAsn: 1.11 ± 0.487
0.833TrpPro: 0.833 ± 0.492
0.555TrpGln: 0.555 ± 0.328
0.555TrpArg: 0.555 ± 0.328
1.943TrpSer: 1.943 ± 0.533
0.0TrpThr: 0.0 ± 0.0
0.833TrpVal: 0.833 ± 0.779
0.555TrpTrp: 0.555 ± 0.31
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.943TyrAla: 1.943 ± 1.237
0.833TyrCys: 0.833 ± 0.665
1.943TyrAsp: 1.943 ± 0.69
2.498TyrGlu: 2.498 ± 0.771
2.775TyrPhe: 2.775 ± 0.916
1.665TyrGly: 1.665 ± 0.984
1.388TyrHis: 1.388 ± 0.616
1.665TyrIle: 1.665 ± 0.735
1.388TyrLys: 1.388 ± 0.54
4.718TyrLeu: 4.718 ± 0.732
1.11TyrMet: 1.11 ± 0.637
1.665TyrAsn: 1.665 ± 0.911
2.22TyrPro: 2.22 ± 0.591
1.943TyrGln: 1.943 ± 0.573
2.775TyrArg: 2.775 ± 0.774
1.943TyrSer: 1.943 ± 1.148
2.22TyrThr: 2.22 ± 0.908
0.555TyrVal: 0.555 ± 0.31
0.833TyrTrp: 0.833 ± 0.566
0.833TyrTyr: 0.833 ± 0.328
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3604 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski