Amino acid dipepetide frequency for Bovine foamy virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.997AlaAla: 2.997 ± 1.002
0.599AlaCys: 0.599 ± 0.874
2.697AlaAsp: 2.697 ± 1.302
3.896AlaGlu: 3.896 ± 0.801
1.798AlaPhe: 1.798 ± 0.756
3.296AlaGly: 3.296 ± 0.789
2.098AlaHis: 2.098 ± 0.657
2.697AlaIle: 2.697 ± 0.618
3.596AlaLys: 3.596 ± 1.494
8.091AlaLeu: 8.091 ± 3.007
0.899AlaMet: 0.899 ± 0.461
1.798AlaAsn: 1.798 ± 0.939
4.795AlaPro: 4.795 ± 3.282
3.296AlaGln: 3.296 ± 0.858
2.997AlaArg: 2.997 ± 1.163
3.596AlaSer: 3.596 ± 0.858
5.993AlaThr: 5.993 ± 0.866
4.795AlaVal: 4.795 ± 1.991
0.599AlaTrp: 0.599 ± 0.508
1.498AlaTyr: 1.498 ± 0.638
0.0AlaXaa: 0.0 ± 0.0
Cys
0.899CysAla: 0.899 ± 0.421
0.599CysCys: 0.599 ± 0.402
0.0CysAsp: 0.0 ± 0.0
1.498CysGlu: 1.498 ± 0.41
0.0CysPhe: 0.0 ± 0.0
2.098CysGly: 2.098 ± 0.274
0.599CysHis: 0.599 ± 0.252
0.899CysIle: 0.899 ± 0.395
1.199CysLys: 1.199 ± 0.566
1.199CysLeu: 1.199 ± 0.67
0.0CysMet: 0.0 ± 0.0
0.599CysAsn: 0.599 ± 0.404
2.098CysPro: 2.098 ± 0.274
1.199CysGln: 1.199 ± 0.808
1.498CysArg: 1.498 ± 0.744
1.199CysSer: 1.199 ± 0.753
0.899CysThr: 0.899 ± 0.479
0.899CysVal: 0.899 ± 0.257
1.199CysTrp: 1.199 ± 0.735
2.098CysTyr: 2.098 ± 0.968
0.0CysXaa: 0.0 ± 0.0
Asp
2.697AspAla: 2.697 ± 0.961
1.798AspCys: 1.798 ± 1.191
2.997AspAsp: 2.997 ± 2.045
2.098AspGlu: 2.098 ± 0.946
2.397AspPhe: 2.397 ± 0.797
2.397AspGly: 2.397 ± 0.814
1.798AspHis: 1.798 ± 0.493
2.098AspIle: 2.098 ± 0.895
1.498AspLys: 1.498 ± 0.555
5.694AspLeu: 5.694 ± 1.231
0.899AspMet: 0.899 ± 0.975
2.098AspAsn: 2.098 ± 0.997
4.195AspPro: 4.195 ± 2.733
1.798AspGln: 1.798 ± 0.718
2.098AspArg: 2.098 ± 0.563
4.495AspSer: 4.495 ± 1.273
2.397AspThr: 2.397 ± 1.104
3.296AspVal: 3.296 ± 1.01
1.199AspTrp: 1.199 ± 0.433
3.596AspTyr: 3.596 ± 0.665
0.0AspXaa: 0.0 ± 0.0
Glu
2.397GluAla: 2.397 ± 1.391
2.397GluCys: 2.397 ± 0.457
3.896GluAsp: 3.896 ± 1.91
5.993GluGlu: 5.993 ± 1.369
0.599GluPhe: 0.599 ± 0.433
1.798GluGly: 1.798 ± 0.583
0.899GluHis: 0.899 ± 0.65
5.694GluIle: 5.694 ± 0.5
2.098GluLys: 2.098 ± 0.837
4.795GluLeu: 4.795 ± 0.784
1.798GluMet: 1.798 ± 0.517
2.098GluAsn: 2.098 ± 0.341
3.596GluPro: 3.596 ± 0.673
2.997GluGln: 2.997 ± 0.792
3.296GluArg: 3.296 ± 0.579
2.397GluSer: 2.397 ± 0.787
2.098GluThr: 2.098 ± 0.704
2.997GluVal: 2.997 ± 0.538
1.199GluTrp: 1.199 ± 1.006
0.599GluTyr: 0.599 ± 0.252
0.0GluXaa: 0.0 ± 0.0
Phe
1.498PheAla: 1.498 ± 0.498
0.899PheCys: 0.899 ± 0.467
1.199PheAsp: 1.199 ± 0.67
1.498PheGlu: 1.498 ± 0.789
0.0PhePhe: 0.0 ± 0.0
1.498PheGly: 1.498 ± 0.676
0.599PheHis: 0.599 ± 0.376
0.599PheIle: 0.599 ± 0.402
1.199PheLys: 1.199 ± 0.433
2.697PheLeu: 2.697 ± 0.643
0.3PheMet: 0.3 ± 0.437
0.599PheAsn: 0.599 ± 0.368
0.599PhePro: 0.599 ± 0.252
1.199PheGln: 1.199 ± 0.535
1.498PheArg: 1.498 ± 0.909
2.997PheSer: 2.997 ± 0.708
2.697PheThr: 2.697 ± 1.015
0.3PheVal: 0.3 ± 0.217
0.899PheTrp: 0.899 ± 0.572
0.599PheTyr: 0.599 ± 0.433
0.0PheXaa: 0.0 ± 0.0
Gly
1.798GlyAla: 1.798 ± 0.601
0.899GlyCys: 0.899 ± 0.548
3.596GlyAsp: 3.596 ± 1.364
1.498GlyGlu: 1.498 ± 0.565
2.397GlyPhe: 2.397 ± 1.04
3.296GlyGly: 3.296 ± 2.217
2.697GlyHis: 2.697 ± 0.815
3.896GlyIle: 3.896 ± 0.706
2.997GlyLys: 2.997 ± 1.027
4.495GlyLeu: 4.495 ± 0.7
0.3GlyMet: 0.3 ± 0.217
4.795GlyAsn: 4.795 ± 1.551
6.892GlyPro: 6.892 ± 3.201
4.795GlyGln: 4.795 ± 2.516
3.896GlyArg: 3.896 ± 0.925
2.697GlySer: 2.697 ± 0.618
3.596GlyThr: 3.596 ± 0.827
2.098GlyVal: 2.098 ± 0.839
0.599GlyTrp: 0.599 ± 0.78
2.697GlyTyr: 2.697 ± 0.977
0.0GlyXaa: 0.0 ± 0.0
His
1.798HisAla: 1.798 ± 0.627
0.899HisCys: 0.899 ± 0.667
2.098HisAsp: 2.098 ± 0.881
1.498HisGlu: 1.498 ± 0.612
0.3HisPhe: 0.3 ± 0.254
0.599HisGly: 0.599 ± 0.376
0.599HisHis: 0.599 ± 0.252
2.397HisIle: 2.397 ± 0.832
0.599HisLys: 0.599 ± 0.433
5.694HisLeu: 5.694 ± 1.113
0.3HisMet: 0.3 ± 0.254
0.3HisAsn: 0.3 ± 0.38
2.697HisPro: 2.697 ± 0.671
1.199HisGln: 1.199 ± 0.866
1.798HisArg: 1.798 ± 0.629
1.498HisSer: 1.498 ± 0.834
2.697HisThr: 2.697 ± 1.401
1.498HisVal: 1.498 ± 0.626
0.3HisTrp: 0.3 ± 0.39
0.899HisTyr: 0.899 ± 0.457
0.0HisXaa: 0.0 ± 0.0
Ile
4.195IleAla: 4.195 ± 0.643
1.798IleCys: 1.798 ± 0.583
1.798IleAsp: 1.798 ± 1.3
1.798IleGlu: 1.798 ± 0.499
1.199IlePhe: 1.199 ± 0.354
2.997IleGly: 2.997 ± 0.996
3.296IleHis: 3.296 ± 0.637
5.394IleIle: 5.394 ± 0.636
3.296IleLys: 3.296 ± 0.907
5.094IleLeu: 5.094 ± 1.172
1.199IleMet: 1.199 ± 0.545
1.498IleAsn: 1.498 ± 0.638
4.795IlePro: 4.795 ± 1.581
2.397IleGln: 2.397 ± 1.008
4.195IleArg: 4.195 ± 0.971
2.697IleSer: 2.697 ± 0.516
3.896IleThr: 3.896 ± 0.726
2.997IleVal: 2.997 ± 0.991
0.599IleTrp: 0.599 ± 0.508
2.397IleTyr: 2.397 ± 1.133
0.0IleXaa: 0.0 ± 0.0
Lys
3.596LysAla: 3.596 ± 1.597
0.3LysCys: 0.3 ± 0.254
1.798LysAsp: 1.798 ± 0.622
2.997LysGlu: 2.997 ± 1.11
1.199LysPhe: 1.199 ± 0.619
2.697LysGly: 2.697 ± 0.849
1.199LysHis: 1.199 ± 0.808
2.098LysIle: 2.098 ± 0.975
2.098LysLys: 2.098 ± 0.902
5.993LysLeu: 5.993 ± 1.535
0.599LysMet: 0.599 ± 0.252
2.098LysAsn: 2.098 ± 0.8
5.094LysPro: 5.094 ± 1.777
2.098LysGln: 2.098 ± 0.937
2.397LysArg: 2.397 ± 0.865
1.798LysSer: 1.798 ± 0.493
2.697LysThr: 2.697 ± 1.015
3.296LysVal: 3.296 ± 1.787
1.798LysTrp: 1.798 ± 0.682
2.397LysTyr: 2.397 ± 0.698
0.0LysXaa: 0.0 ± 0.0
Leu
6.293LeuAla: 6.293 ± 1.024
1.498LeuCys: 1.498 ± 0.786
5.094LeuAsp: 5.094 ± 1.764
6.593LeuGlu: 6.593 ± 1.073
3.296LeuPhe: 3.296 ± 1.081
7.791LeuGly: 7.791 ± 1.263
3.596LeuHis: 3.596 ± 1.277
5.094LeuIle: 5.094 ± 1.451
7.192LeuLys: 7.192 ± 2.35
7.791LeuLeu: 7.791 ± 2.42
2.098LeuMet: 2.098 ± 0.539
4.795LeuAsn: 4.795 ± 1.141
8.391LeuPro: 8.391 ± 1.77
6.593LeuGln: 6.593 ± 1.166
4.795LeuArg: 4.795 ± 0.287
4.495LeuSer: 4.495 ± 1.497
6.892LeuThr: 6.892 ± 1.624
4.195LeuVal: 4.195 ± 1.121
2.098LeuTrp: 2.098 ± 0.622
1.199LeuTyr: 1.199 ± 0.354
0.0LeuXaa: 0.0 ± 0.0
Met
3.296MetAla: 3.296 ± 0.937
0.3MetCys: 0.3 ± 0.39
1.498MetAsp: 1.498 ± 0.653
0.599MetGlu: 0.599 ± 0.508
0.0MetPhe: 0.0 ± 0.0
0.3MetGly: 0.3 ± 0.217
0.3MetHis: 0.3 ± 0.217
1.498MetIle: 1.498 ± 1.177
0.899MetLys: 0.899 ± 0.395
0.599MetLeu: 0.599 ± 0.874
0.3MetMet: 0.3 ± 0.39
1.199MetAsn: 1.199 ± 0.695
0.899MetPro: 0.899 ± 0.502
0.899MetGln: 0.899 ± 0.88
1.498MetArg: 1.498 ± 0.94
0.0MetSer: 0.0 ± 0.0
0.899MetThr: 0.899 ± 0.311
0.599MetVal: 0.599 ± 0.252
0.0MetTrp: 0.0 ± 0.0
0.3MetTyr: 0.3 ± 0.217
0.0MetXaa: 0.0 ± 0.0
Asn
2.098AsnAla: 2.098 ± 0.839
0.899AsnCys: 0.899 ± 0.65
1.798AsnAsp: 1.798 ± 0.797
1.498AsnGlu: 1.498 ± 0.496
2.397AsnPhe: 2.397 ± 0.443
2.997AsnGly: 2.997 ± 0.655
0.599AsnHis: 0.599 ± 0.433
1.199AsnIle: 1.199 ± 0.684
2.098AsnLys: 2.098 ± 0.717
5.094AsnLeu: 5.094 ± 1.313
0.0AsnMet: 0.0 ± 0.0
3.596AsnAsn: 3.596 ± 1.379
4.495AsnPro: 4.495 ± 1.459
3.596AsnGln: 3.596 ± 1.566
2.397AsnArg: 2.397 ± 1.764
4.495AsnSer: 4.495 ± 0.849
2.697AsnThr: 2.697 ± 0.955
1.798AsnVal: 1.798 ± 0.914
0.899AsnTrp: 0.899 ± 0.467
1.798AsnTyr: 1.798 ± 0.769
0.0AsnXaa: 0.0 ± 0.0
Pro
7.791ProAla: 7.791 ± 4.841
0.599ProCys: 0.599 ± 0.252
3.296ProAsp: 3.296 ± 0.684
3.596ProGlu: 3.596 ± 2.149
1.199ProPhe: 1.199 ± 0.574
6.293ProGly: 6.293 ± 1.904
2.997ProHis: 2.997 ± 0.538
4.195ProIle: 4.195 ± 1.464
3.896ProLys: 3.896 ± 1.123
8.391ProLeu: 8.391 ± 1.656
1.498ProMet: 1.498 ± 1.161
3.596ProAsn: 3.596 ± 1.639
8.69ProPro: 8.69 ± 4.317
5.993ProGln: 5.993 ± 2.182
4.495ProArg: 4.495 ± 2.443
3.296ProSer: 3.296 ± 0.915
3.896ProThr: 3.896 ± 0.694
5.094ProVal: 5.094 ± 1.434
1.199ProTrp: 1.199 ± 0.474
2.997ProTyr: 2.997 ± 0.268
0.0ProXaa: 0.0 ± 0.0
Gln
2.997GlnAla: 2.997 ± 0.792
2.397GlnCys: 2.397 ± 0.817
4.495GlnAsp: 4.495 ± 1.528
3.896GlnGlu: 3.896 ± 1.16
0.0GlnPhe: 0.0 ± 0.0
5.094GlnGly: 5.094 ± 2.054
2.098GlnHis: 2.098 ± 0.877
2.098GlnIle: 2.098 ± 0.704
3.596GlnLys: 3.596 ± 1.632
4.495GlnLeu: 4.495 ± 1.346
1.199GlnMet: 1.199 ± 0.892
3.896GlnAsn: 3.896 ± 1.051
5.694GlnPro: 5.694 ± 3.25
2.997GlnGln: 2.997 ± 1.406
2.098GlnArg: 2.098 ± 1.678
2.397GlnSer: 2.397 ± 0.491
2.997GlnThr: 2.997 ± 0.991
2.697GlnVal: 2.697 ± 0.838
1.199GlnTrp: 1.199 ± 0.67
1.798GlnTyr: 1.798 ± 0.416
0.0GlnXaa: 0.0 ± 0.0
Arg
2.397ArgAla: 2.397 ± 0.832
1.199ArgCys: 1.199 ± 0.443
2.098ArgAsp: 2.098 ± 0.782
2.397ArgGlu: 2.397 ± 0.457
1.798ArgPhe: 1.798 ± 1.295
4.495ArgGly: 4.495 ± 1.905
0.599ArgHis: 0.599 ± 0.534
2.098ArgIle: 2.098 ± 0.471
2.697ArgLys: 2.697 ± 0.838
5.094ArgLeu: 5.094 ± 1.194
0.599ArgMet: 0.599 ± 0.252
2.997ArgAsn: 2.997 ± 1.443
3.896ArgPro: 3.896 ± 1.471
3.596ArgGln: 3.596 ± 1.489
6.892ArgArg: 6.892 ± 1.624
2.997ArgSer: 2.997 ± 0.776
3.596ArgThr: 3.596 ± 1.329
3.596ArgVal: 3.596 ± 1.954
1.798ArgTrp: 1.798 ± 0.493
2.098ArgTyr: 2.098 ± 1.337
0.0ArgXaa: 0.0 ± 0.0
Ser
5.094SerAla: 5.094 ± 1.841
0.899SerCys: 0.899 ± 0.421
3.896SerAsp: 3.896 ± 1.203
2.397SerGlu: 2.397 ± 1.083
0.899SerPhe: 0.899 ± 0.572
3.296SerGly: 3.296 ± 1.354
0.899SerHis: 0.899 ± 0.467
4.495SerIle: 4.495 ± 2.079
2.697SerLys: 2.697 ± 0.966
6.293SerLeu: 6.293 ± 2.776
0.899SerMet: 0.899 ± 0.246
2.397SerAsn: 2.397 ± 0.814
3.296SerPro: 3.296 ± 0.958
3.296SerGln: 3.296 ± 1.162
3.896SerArg: 3.896 ± 1.561
5.694SerSer: 5.694 ± 2.37
3.896SerThr: 3.896 ± 1.082
1.798SerVal: 1.798 ± 0.877
1.498SerTrp: 1.498 ± 0.549
1.798SerTyr: 1.798 ± 0.791
0.0SerXaa: 0.0 ± 0.0
Thr
5.094ThrAla: 5.094 ± 1.387
0.899ThrCys: 0.899 ± 0.461
3.296ThrAsp: 3.296 ± 0.99
2.397ThrGlu: 2.397 ± 1.099
1.199ThrPhe: 1.199 ± 0.67
3.596ThrGly: 3.596 ± 0.243
2.098ThrHis: 2.098 ± 0.471
3.596ThrIle: 3.596 ± 0.785
1.798ThrLys: 1.798 ± 0.996
7.492ThrLeu: 7.492 ± 0.762
0.3ThrMet: 0.3 ± 0.217
1.498ThrAsn: 1.498 ± 0.316
5.993ThrPro: 5.993 ± 1.857
3.296ThrGln: 3.296 ± 0.816
2.997ThrArg: 2.997 ± 0.869
4.495ThrSer: 4.495 ± 1.052
3.296ThrThr: 3.296 ± 0.862
3.896ThrVal: 3.896 ± 0.822
2.397ThrTrp: 2.397 ± 0.613
2.098ThrTyr: 2.098 ± 1.149
0.0ThrXaa: 0.0 ± 0.0
Val
2.997ValAla: 2.997 ± 0.644
1.498ValCys: 1.498 ± 0.345
2.997ValAsp: 2.997 ± 1.069
2.697ValGlu: 2.697 ± 1.373
2.098ValPhe: 2.098 ± 1.235
2.098ValGly: 2.098 ± 0.36
1.498ValHis: 1.498 ± 0.338
3.896ValIle: 3.896 ± 0.713
0.899ValLys: 0.899 ± 0.457
5.993ValLeu: 5.993 ± 1.55
1.798ValMet: 1.798 ± 1.055
3.596ValAsn: 3.596 ± 0.416
2.397ValPro: 2.397 ± 1.478
2.997ValGln: 2.997 ± 0.41
1.498ValArg: 1.498 ± 0.969
3.296ValSer: 3.296 ± 0.42
2.997ValThr: 2.997 ± 0.869
2.697ValVal: 2.697 ± 1.194
1.498ValTrp: 1.498 ± 0.345
2.697ValTyr: 2.697 ± 0.814
0.0ValXaa: 0.0 ± 0.0
Trp
0.599TrpAla: 0.599 ± 0.433
0.0TrpCys: 0.0 ± 0.0
1.498TrpAsp: 1.498 ± 0.426
2.397TrpGlu: 2.397 ± 0.561
0.3TrpPhe: 0.3 ± 0.254
0.899TrpGly: 0.899 ± 0.725
0.3TrpHis: 0.3 ± 0.254
2.098TrpIle: 2.098 ± 1.149
1.798TrpLys: 1.798 ± 0.988
1.798TrpLeu: 1.798 ± 0.496
0.0TrpMet: 0.0 ± 0.0
0.599TrpAsn: 0.599 ± 0.508
1.498TrpPro: 1.498 ± 0.685
1.798TrpGln: 1.798 ± 0.603
1.498TrpArg: 1.498 ± 0.693
1.798TrpSer: 1.798 ± 0.622
1.798TrpThr: 1.798 ± 0.958
0.899TrpVal: 0.899 ± 1.033
1.199TrpTrp: 1.199 ± 0.535
1.199TrpTyr: 1.199 ± 0.866
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.498TyrAla: 1.498 ± 0.345
0.3TyrCys: 0.3 ± 0.217
1.498TyrAsp: 1.498 ± 0.942
2.397TyrGlu: 2.397 ± 1.162
0.3TyrPhe: 0.3 ± 0.217
2.397TyrGly: 2.397 ± 1.138
0.899TyrHis: 0.899 ± 0.65
1.498TyrIle: 1.498 ± 0.626
2.098TyrLys: 2.098 ± 0.902
2.997TyrLeu: 2.997 ± 1.808
0.599TyrMet: 0.599 ± 0.404
2.397TyrAsn: 2.397 ± 0.71
3.296TyrPro: 3.296 ± 1.25
2.098TyrGln: 2.098 ± 0.621
1.199TyrArg: 1.199 ± 0.33
2.997TyrSer: 2.997 ± 1.11
1.798TyrThr: 1.798 ± 0.53
2.697TyrVal: 2.697 ± 1.373
1.798TyrTrp: 1.798 ± 0.791
1.199TyrTyr: 1.199 ± 0.695
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3338 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski